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Yuexi Shi

Research Profile

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Xiaoyang Ling; Wendy Schober; Yuexi Shi; Erika L Spaeth; Weiguo Zhang; Ye Chen; Numsen Hail; Marina Konopleva; Michael Andreeff
The CXCR4 antagonist AMD3465 regulates oncogenic signaling and invasiveness in vitro and prevents breast cancer growth and metastasis in vivo.
Twee Tsao; Ninaxiang Zhang; Michael Andreeff; Ansu Antony; Kevin R Coombes; Kensuke Kojima; Sergej Konoplev; Steven Kornblau; Hongbo Lu; Yi Hua Qiu; Vivian Ruvolo; Yuexi Shi; Marina Konopleva
Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells.
Bing Z Carter; R Chen; J M Fidler; Xiaoyang Ling; Duncan H Mak; W Plunkett; Yuexi Shi; Michael Andreeff
MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML.

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2013: Xiaoyang Ling; Wendy Schober; Yuexi Shi; Erika L Spaeth; Weiguo Zhang; Ye Chen; Numsen Hail; Marina Konopleva; Michael Andreeff
The CXCR4 antagonist AMD3465 regulates oncogenic signaling and invasiveness in vitro and prevents breast cancer growth and metastasis in vivo.
PloS one 2013;8(3):e58426.
2012: Twee Tsao; Ninaxiang Zhang; Michael Andreeff; Ansu Antony; Kevin R Coombes; Kensuke Kojima; Sergej Konoplev; Steven Kornblau; Hongbo Lu; Yi Hua Qiu; Vivian Ruvolo; Yuexi Shi; Marina Konopleva
Concomitant inhibition of DNA methyltransferase and BCL-2 protein function synergistically induce mitochondrial apoptosis in acute myelogenous leukemia cells.
Annals of hematology 2012;91(12):1861-70.
2012: Bing Z Carter; R Chen; J M Fidler; Xiaoyang Ling; Duncan H Mak; W Plunkett; Yuexi Shi; Michael Andreeff
MRx102, a triptolide derivative, has potent antileukemic activity in vitro and in a murine model of AML.
Leukemia 2012;26(3):443-50.
2011: Juliana Benito; Ingrid Boehm; Gautam Borthakur; Carlos Bueso-Ramos; Dario Campana; Hernan Carol; Wendy Fang; Craig T Jordan; Hagop Kantarjian; Sergej Konoplev; Richard Lock; Hongbo Lu; Yuexi Shi; Elizabeth Shpall; Barbara Szymanska; Deborah A Thomas; William R Wilson; Patrick A Zweidler-McKay; Michael Andreeff; Marina Konopleva
Pronounced hypoxia in models of murine and human leukemia: high efficacy of hypoxia-activated prodrug PR-104.
PloS one 2011;6(8):e23108.
2010: Shannon Kidd; Lisa Caldwell; Martin Dietrich; Ismael Samudio; Erika L Spaeth; Keri Watson; Yuexi Shi; James Abbruzzese; Marina Konopleva; Michael Andreeff; Frank C Marini
Mesenchymal stromal cells alone or expressing interferon-beta suppress pancreatic tumors in vivo, an effect countered by anti-inflammatory treatment.
Cytotherapy 2010;12(5):615-25.
2010: Venkata Lokesh Battula; Kurt William Evans; Brett George Hollier; Yuexi Shi; Frank C Marini; Ayyakkannu Ayyanan; Rui-Yu Wang; Cathrin Brisken; Rudy Guerra; Michael Andreeff; Sendurai A Mani
Epithelial-mesenchymal transition-derived cells exhibit multilineage differentiation potential similar to mesenchymal stem cells.
Stem cells (Dayton, Ohio) 2010;28(8):1435-45.
2010: Xiaoyang Ling; Frank Marini; Marina Konopleva; Wendy Schober; Yuexi Shi; Jared Burks; Karen Clise-Dwyer; Rui-Yu Wang; Weiguo Zhang; Xiaoqing Yuan; Hongbo Lu; Lisa Caldwell; Michael Andreeff
Mesenchymal Stem Cells Overexpressing IFN-β Inhibit Breast Cancer Growth and Metastases through Stat3 Signaling in a Syngeneic Tumor Model.
Cancer microenvironment : official journal of the International Cancer Microenvironment Society 2010;3(1):83-95.
2007: Yoko Tabe; Marina Konopleva; Yutaka Kondo; Rooha Contractor; Twee Tsao; Sergej Konoplev; Yuexi Shi; Xiaoyang Ling; Julie C Watt; Yuko Tsutsumi-Ishii; Akimichi Ohsaka; Isao Nagaoka; Jean-Pierre J Issa; Scott C Kogan; Michael Andreeff
PPARgamma-active triterpenoid CDDO enhances ATRA-induced differentiation in APL.
Cancer biology & therapy 2007;6(12):1967-77.
2006: Bing Z Carter; Duncan H Mak; Yuexi Shi; Wendy D Schober; Rui-Yu Wang; Marina Konopleva; Erich Koller; Nicholas Dean; Michael Andreeff
Regulation and targeting of Eg5, a mitotic motor protein in blast crisis CML: overcoming imatinib resistance.
Cell cycle (Georgetown, Tex.) 2006;5(19):2223-9.
2005: Marina Konopleva; Yuexi Shi; Linda Steelman; John G Shelton; Mark F Munsell; Frank C Marini; Teresa McQueen; Rooha Contractor; James A McCubrey; Michael Andreeff
Development of a conditional in vivo model to evaluate the efficacy of small molecule inhibitors for the treatment of Raf-transformed hematopoietic cells.
Cancer research 2005;65(21):9962-70.
2002: Dimpy Koul; Samar A Jasser; Yiling Lu; Michael A Davies; Ruijun Shen; Yuexi Shi; Gordon B Mills; W K Alfred Yung
Motif analysis of the tumor suppressor gene MMAC/PTEN identifies tyrosines critical for tumor suppression and lipid phosphatase activity.
Oncogene 2002;21(15):2357-64.