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Shigeki Shibahara

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Co-Publications
Name
60
Takahashi, Kazuhiro
40
Takeda, Kazuhisa
29
Murakami, Osamu
24
Totsune, Kazuhito
20
Udono, Tetsuo
17
Nakayama, Masaharu
16
Furuyama, Kazumichi
13
Kitamuro, Tomomi
13
Yasumoto, K i
13
Shirato, Kunio
12
Saito, Hideo
10
Sone, Masahiko
10
Tamai, Makoto
9
Yokoyama, Satoru
8
Amae, S

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Publications

TOP 3
Numata Ikuko; Okuyama Ryuhei; Memezawa Ai; Ito Yumiko; Takeda Kazuhisa; Furuyama Kazumichi; Shibahara Shigeki; Aiba Setsuya
Functional expression of heme oxygenase-1 in human differentiated epidermis and its regulation by cytokines.
Han Feng; Takeda Kazuhisa; Ishikawa Kazunobu; Ono Masao; Date Fumiko; Yokoyama Satoru; Furuyama Kazumichi; Shinozawa Yotaro; Urade Yoshihiro; Shibahara Shigeki
Induction of lipocalin-type prostaglandin D synthase in mouse heart under hypoxemia.
Kaneko Kiriko; Furuyama Kazumichi; Aburatani Hiroyuki; Shibahara Shigeki
Hypoxia induces erythroid-specific 5-aminolevulinate synthase expression in human erythroid cells through transforming growth factor-beta signaling.

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All Publications

2009: Numata Ikuko; Okuyama Ryuhei; Memezawa Ai; Ito Yumiko; Takeda Kazuhisa; Furuyama Kazumichi; Shibahara Shigeki; Aiba Setsuya
Functional expression of heme oxygenase-1 in human differentiated epidermis and its regulation by cytokines.
The Journal of investigative dermatology 2009;129(11):2594-603.
2009: Han Feng; Takeda Kazuhisa; Ishikawa Kazunobu; Ono Masao; Date Fumiko; Yokoyama Satoru; Furuyama Kazumichi; Shinozawa Yotaro; Urade Yoshihiro; Shibahara Shigeki
Induction of lipocalin-type prostaglandin D synthase in mouse heart under hypoxemia.
Biochemical and biophysical research communications 2009;385(3):449-53.
2009: Kaneko Kiriko; Furuyama Kazumichi; Aburatani Hiroyuki; Shibahara Shigeki
Hypoxia induces erythroid-specific 5-aminolevulinate synthase expression in human erythroid cells through transforming growth factor-beta signaling.
The FEBS journal 2009;276(5):1370-82.
2009: Tsukiji Nagaharu; Nishihara Daisuke; Yajima Ichiro; Takeda Kazuhisa; Shibahara Shigeki; Yamamoto Hiroaki
Mitf functions as an in ovo regulator for cell differentiation and proliferation during development of the chick RPE.
Developmental biology 2009;326(2):335-46.
2009: Uehara Shigeyuki; Izumi Yoshiko; Kubo Yuko; Wang Chi Chiu; Mineta Katsuhiko; Ikeo Kazuho; Gojobori Takashi; Tachibana Masayoshi; Kikuchi Toshihiko; Kobayashi Toshimitsu; Shibahara Shigeki; Taya Choji; Yonekawa Hiromichi; Shiroishi Toshihiko; Yamamoto Hiroaki
Specific expression of Gsta4 in mouse cochlear melanocytes: a novel role for hearing and melanocyte differentiation.
Pigment cell & melanoma research 2009;22(1):111-9.
2008: Vargas Patrick D; Furuyama Kazumichi; Sassa Shigeru; Shibahara Shigeki
Hypoxia decreases the expression of the two enzymes responsible for producing linear and cyclic tetrapyrroles in the heme biosynthetic pathway.
The FEBS journal 2008;275(23):5947-59.
2008: Satarug Soisungwan; Wisedpanichkij Raewadee; Takeda Kazuhisa; Li Bin; Na-Bangchang Kesara; Moore Michael R; Shibahara Shigeki
Prostaglandin D2 induces heme oxygenase-1 mRNA expression through the DP2 receptor.
Biochemical and biophysical research communications 2008;377(3):878-83.
2008: Satarug Soisungwan; Kikuchi Mihoko; Wisedpanichkij Raewadee; Li Bin; Takeda Kazuhisa; Na-Bangchang Kesara; Moore Michael R; Hirayama Kenji; Shibahara Shigeki
Prevention of cadmium accumulation in retinal pigment epithelium with manganese and zinc.
Experimental eye research 2008;87(6):587-93.
2008: Li Bin; Takeda Kazuhisa; Yokoyama Satoru; Shibahara Shigeki
A prolyl-hydroxylase inhibitor, ethyl-3,4-dihydroxybenzoate, induces haem oxygenase-1 expression in human cells through a mechanism independent of hypoxia-inducible factor-1alpha.
Journal of biochemistry 2008;144(5):643-54.
2008: Kuesap Jiraporn; Li Bin; Satarug Soisungwan; Takeda Kazuhisa; Numata Ikuko; Na-Bangchang Kesara; Shibahara Shigeki
Prostaglandin D2 induces heme oxygenase-1 in human retinal pigment epithelial cells.
Biochemical and biophysical research communications 2008;367(2):413-9.
2008: Zhang Yan; Li Yin; Shibahara Shigeki; Takahashi Kazuhiro
Synergistic activation of the human adrenomedullin gene promoter by Sp1 and AP-2alpha.
Peptides 2008;29(3):465-72.
2007: Shibahara Shigeki; Han Feng; Li Bin; Takeda Kazuhisa
Hypoxia and heme oxygenases: oxygen sensing and regulation of expression.
Antioxidants & redox signaling 2007;9(12):2209-25.
2007: Takeda Kazuhisa; Takahashi Na-Ho; Shibahara Shigeki
Neuroendocrine functions of melanocytes: beyond the skin-deep melanin maker.
The Tohoku journal of experimental medicine 2007;211(3):201-21.
2007: Takeda Kazuhisa; Adachi Tetsuya; Han Feng; Yokoyama Satoru; Yamamoto Hiroaki; Hida Wataru; Shibahara Shigeki
Augmented chemosensitivity in black-eyed white Mitfmi-bw mice, lacking melanocytes.
Journal of biochemistry 2007;141(3):327-33.
2006: Ding Yuanying; Zhang Yong Z; Furuyama Kazumichi; Ogawa Kazuhiro; Igarashi Kazuhiko; Shibahara Shigeki
Down-regulation of heme oxygenase-2 is associated with the increased expression of heme oxygenase-1 in human cell lines.
The FEBS journal 2006;273(23):5333-46.
2006: Li Yin; Zhang Yan; Shibahara Shigeki; Takahashi Kazuhiro
Adrenomedullin in adipocyte differentiation of human mesenchymal stem cells.
Biochemical and biophysical research communications 2006;350(3):616-22.
2006: Zhang Yan; Li Yin; Totsune Kazuhito; Kikuchi Kumi; Murakami Osamu; Shibahara Shigeki; Takahashi Kazuhiro
Hypoxia increases endothelin-1 mRNA expression but not immunoreactive endothelin in the medium of T98G glioblastoma cells under cytokine treatment.
Peptides 2006;27(11):3003-6.
2006: Yokoyama Satoru; Takeda Kazuhisa; Shibahara Shigeki
Functional difference of the SOX10 mutant proteins responsible for the phenotypic variability in auditory-pigmentary disorders.
Journal of biochemistry 2006;140(4):491-9.
2006: Zhang Yongzhao; Furuyama Kazumichi; Kaneko Kiriko; Ding Yuanying; Ogawa Kazuhiro; Yoshizawa Miki; Kawamura Masaki; Takeda Kazuhisa; Yoshida Tadashi; Shibahara Shigeki
Hypoxia reduces the expression of heme oxygenase-2 in various types of human cell lines. A possible strategy for the maintenance of intracellular heme level.
The FEBS journal 2006;273(14):3136-47.
2006: Adachi Tetsuya; Ogawa Hiromasa; Okabe Shinichi; Kitamuro Tomomi; Kikuchi Yoshihiro; Shibahara Shigeki; Shirato Kunio; Hida Wataru
Mice with blunted hypoxic ventilatory response are susceptible to respiratory disturbance during hypoxia.
The Tohoku journal of experimental medicine 2006;209(2):125-34.
2006: Li Yin; Zhang Yan; Furuyama Kazumichi; Yokoyama Satoru; Takeda Kazuhisa; Shibahara Shigeki; Takahashi Kazuhiro
Identification of adipocyte differentiation-related regulatory element for adrenomedullin gene repression (ADRE-AR) in 3T3-L1 cells.
Peptides 2006;27(6):1405-14.
2006: Yokoyama Satoru; Takeda Kazuhisa; Shibahara Shigeki
SOX10, in combination with Sp1, regulates the endothelin receptor type B gene in human melanocyte lineage cells.
The FEBS journal 2006;273(8):1805-20.
2006: Furuyama Kazumichi; Harigae Hideo; Heller Tom; Hamel Ben C J; Minder Elisabeth I; Shimizu Toru; Kuribara Tadao; Blijlevens Nicole; Shibahara Shigeki; Sassa Shigeru
Arg452 substitution of the erythroid-specific 5-aminolaevulinate synthase, a hot spot mutation in X-linked sideroblastic anaemia, does not itself affect enzyme activity.
European journal of haematology 2006;76(1):33-41.
2006: Takeda Kazuhisa; Yokoyama Satoru; Aburatani Hiroyuki; Masuda Takayuki; Han Feng; Yoshizawa Miki; Yamaki Naomi; Yamamoto Hiroaki; Eguchi Naomi; Urade Yoshihiro; Shibahara Shigeki
Lipocalin-type prostaglandin D synthase as a melanocyte marker regulated by MITF.
Biochemical and biophysical research communications 2006;339(4):1098-106.
2006: Zhang Yongzhao; Furuyama Kazumichi; Adachi Tetsuya; Ishikawa Kazunobu; Matsumoto Hayato; Masuda Takayuki; Ogawa Kazuhiro; Takeda Kazuhisa; Yoshizawa Miki; Ogawa Hiromasa; Maruyama Yukio; Hida Wataru; Shibahara Shigeki
Hypoxemia and attenuated hypoxic ventilatory responses in mice lacking heme oxygenase-2: evidence for a novel role of heme oxygenase-2 as an oxygen sensor.
Advances in experimental medicine and biology 2006;580():161-6; discussion 351-9.
2005: Han Feng; Takeda Kazuhisa; Yokoyama Satoru; Ueda Hideo; Shinozawa Yotaro; Furuyama Kazumichi; Shibahara Shigeki
Dynamic changes in expression of heme oxygenases in mouse heart and liver during hypoxia.
Biochemical and biophysical research communications 2005;338(1):653-9.
2004: Udono-Fujimori Reiko; Totsune Kazuhito; Murakami Osamu; Arihara Zenei; Kikuchi Kumi; Tamai Makoto; Shibahara Shigeki; Takahashi Kazuhiro
Suppression of cytokine-induced expression of endothelin-1 by dexamethasone in human retinal pigment epithelial cells.
Journal of cardiovascular pharmacology 2004;44 Suppl 1():S471-3.
2004: Takahashi Kazuhiro; Totsune Kazuhito; Murakami Osamu; Shibahara Shigeki
Urocortins as cardiovascular peptides.
Peptides 2004;25(10):1723-31.
2004: Udono-Fujimori Reiko; Takahashi Kazuhiro; Takeda Kazuhisa; Furuyama Kazumichi; Kaneko Kiriko; Takahashi Shigeru; Tamai Makoto; Shibahara Shigeki
Expression of heme oxygenase-1 is repressed by interferon-gamma and induced by hypoxia in human retinal pigment epithelial cells.
European journal of biochemistry / FEBS 2004;271(14):3076-84.
2004: Adachi Tetsuya; Ishikawa Kazunobu; Hida Wataru; Matsumoto Hayato; Masuda Takayuki; Date Fumiko; Ogawa Kazuhiro; Takeda Kazuhisa; Furuyama Kazumichi; Zhang Yongzhao; Kitamuro Tomomi; Ogawa Hiromasa; Maruyama Yukio; Shibahara Shigeki
Hypoxemia and blunted hypoxic ventilatory responses in mice lacking heme oxygenase-2.
Biochemical and biophysical research communications 2004;320(2):514-22.
2004: Takahashi Kazuhiro; Totsune Kazuhito; Murakami Osamu; Saruta Masayuki; Nakabayashi Masao; Suzuki Takashi; Sasano Hironobu; Shibahara Shigeki
Expression of urocortin III/stresscopin in human heart and kidney.
The Journal of clinical endocrinology and metabolism 2004;89(4):1897-903.
2003: Li Yin; Totsune Kazuhito; Takeda Kazuhisa; Furuyama Kazumichi; Shibahara Shigeki; Takahashi Kazuhiro
Differential expression of adrenomedullin and resistin in 3T3-L1 adipocytes treated with tumor necrosis factor-alpha.
European journal of endocrinology / European Federation of Endocrine Societies 2003;149(3):231-8.
2003: Shibahara Shigeki
The heme oxygenase dilemma in cellular homeostasis: new insights for the feedback regulation of heme catabolism.
The Tohoku journal of experimental medicine 2003;200(4):167-86.
2003: Takahashi Kazuhiro; Udono-Fujimori Reiko; Totsune Kazuhito; Murakami Osamu; Shibahara Shigeki
Suppression of cytokine-induced expression of adrenomedullin and endothelin-1 by dexamethasone in T98G human glioblastoma cells.
Peptides 2003;24(7):1053-62.
2003: Saito Hideo; Takeda Kazuhisa; Yasumoto Ken-ichi; Ohtani Haruo; Watanabe Ken-ichi; Takahashi Kazuhiro; Fukuzaki Atsushi; Arai Yoichi; Yamamoto Hiroaki; Shibahara Shigeki
Germ cell-specific expression of microphthalmia-associated transcription factor mRNA in mouse testis.
Journal of biochemistry 2003;134(1):143-50.
2003: Saito Hideo; Yasumoto Ken-Ichi; Takeda Kazuhisa; Takahashi Kazuhiro; Yamamoto Hiroaki; Shibahara Shigeki
Microphthalmia-associated transcription factor in the Wnt signaling pathway.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2003;16(3):261-5.
2003: Furuyama Kazumichi; Harigae Hideo; Kinoshita Chiharu; Shimada Toshihiko; Miyaoka Kazuko; Kanda Chiaki; Maruyama Yoshifumi; Shibahara Shigeki; Sassa Shigeru
Late-onset X-linked sideroblastic anemia following hemodialysis.
Blood 2003;101(11):4623-4.
2003: Shibahara Shigeki; Nakayama Masaharu; Kitamuro Tomomi; Udono-Fujimori Reiko; Takahashi Kazuhiro
Repression of heme oxygenase-1 expression as a defense strategy in humans.
Experimental biology and medicine (Maywood, N.J.) 2003;228(5):472-3.
2003: Udono-Fujimori Reiko; Udono Tetsuo; Totsune Kazuhito; Tamai Makoto; Shibahara Shigeki; Takahashi Kazuhiro
Adrenomedullin in the eye.
Regulatory peptides 2003;112(1-3):95-101.
2003: Takahashi Kazuhiro; Shibahara Shigeki
[Heme oxygenase-1: for whom is its expression suppressed?]
Seikagaku. The Journal of Japanese Biochemical Society 2003;75(3):213-8.
2003: Morita Masanobu; Ohneda Osamu; Yamashita Toshiharu; Takahashi Satoru; Suzuki Norio; Nakajima Osamu; Kawauchi Shimako; Ema Masatsugu; Shibahara Shigeki; Udono Tetsuo; Tomita Koji; Tamai Makoto; Sogawa Kazuhiro; Yamamoto Masayuki; Fujii-Kuriyama Yoshiaki
HLF/HIF-2alpha is a key factor in retinopathy of prematurity in association with erythropoietin.
The EMBO journal 2003;22(5):1134-46.
2003: Kitamuro Tomomi; Takahashi Kazuhiro; Ogawa Kazuhiro; Udono-Fujimori Reiko; Takeda Kazuhisa; Furuyama Kazumichi; Nakayama Masaharu; Sun Jiying; Fujita Hiroyoshi; Hida Wataru; Hattori Toshio; Shirato Kunio; Igarashi Kazuhiko; Shibahara Shigeki
Bach1 functions as a hypoxia-inducible repressor for the heme oxygenase-1 gene in human cells.
The Journal of biological chemistry 2003;278(11):9125-33.
2003: Takahashi Kazuhiro; Totsune Kazuhito; Murakami Osamu; Arihara Zenei; Noshiro Takao; Hayashi Yutaka; Shibahara Shigeki
Expression of urotensin II and its receptor in adrenal tumors and stimulation of proliferation of cultured tumor cells by urotensin II.
Peptides 2003;24(2):301-6.
2003: Li Yin; Totsune Kazuhito; Takeda Kazuhisa; Furuyama Kazumichi; Shibahara Shigeki; Takahashi Kazuhiro
Decreased expression of adrenomedullin during adipocyte-differentiation of 3T3-L1 cells.
Hypertension research : official journal of the Japanese Society of Hypertension 2003;26 Suppl():S41-4.
2003: Takeda Kazuhisa; Yokoyama Satoru; Yasumoto Ken ichi; Saito Hideo; Udono Tetsuo; Takahashi Kazuhiro; Shibahara Shigeki
OTX2 regulates expression of DOPAchrome tautomerase in human retinal pigment epithelium.
Biochemical and biophysical research communications 2003;300(4):908-14.
2002: Udono Tetsuo; Takahashi Kazuhiro; Abe Toshiaki; Shibahara Shigeki; Tamai Makoto
Elevated immunoreactive-adrenomedullin levels in the aqueous humor of patients with uveitis and vitreoretinal disorders.
Peptides 2002;23(10):1865-8.
2002: Shibahara Shigeki; Kitamuro Tomomi; Takahashi Kazuhiro
Heme degradation and human disease: diversity is the soul of life.
Antioxidants & redox signaling 2002;4(4):593-602.
2002: Takahashi Kazuhiro; Totsune Kazuhito; Kitamuro Tomomi; Sone Masahiko; Murakami Osamu; Shibahara Shigeki
Three vasoactive peptides, endothelin-1, adrenomedullin and urotensin-II, in human tumour cell lines of different origin: expression and effects on proliferation.
Clinical science (London, England : 1979) 2002;103 Suppl 48():35S-38S.
2002: Saito Hideo; Yasumoto Ken-Ichi; Takeda Kazuhisa; Takahashi Kazuhiro; Fukuzaki Atsushi; Orikasa Seiichi; Shibahara Shigeki
Melanocyte-specific microphthalmia-associated transcription factor isoform activates its own gene promoter through physical interaction with lymphoid-enhancing factor 1.
The Journal of biological chemistry 2002;277(32):28787-94.
2002: Takahashi Kazuhiro; Totsune Kazuhito; Murakami Osamu; Sone Masahiko; Noshiro Takao; Hayashi Yutaka; Sasano Hironobu; Shibahara Shigeki
Expression of prolactin-releasing peptide and its receptor in the human adrenal glands and tumor tissues of adrenocortical tumors, pheochromocytomas and neuroblastomas.
Peptides 2002;23(6):1135-40.
2002: Yasumoto Ken-ichi; Takeda Kazuhisa; Saito Hideo; Watanabe Ken-ichi; Takahashi Kazuhiro; Shibahara Shigeki
Microphthalmia-associated transcription factor interacts with LEF-1, a mediator of Wnt signaling.
The EMBO journal 2002;21(11):2703-14.
2002: Watanabe Ken-Ichi; Takeda Kazuhisa; Yasumoto Ken-Ichi; Udono Tetsuo; Saito Hideo; Ikeda Katsuhisa; Takasaka Tomonori; Takahashi Kazuhiro; Kobayashi Toshimitsu; Tachibana Masayoshi; Shibahara Shigeki
Identification of a distal enhancer for the melanocyte-specific promoter of the MITF gene.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2002;15(3):201-11.
2002: Takeda Kazuhisa; Yasumoto Ken ichi; Kawaguchi Naoko; Udono Tetsuo; Watanabe Ken ichi; Saito Hideo; Takahashi Kazuhiro; Noda Masaki; Shibahara Shigeki
Mitf-D, a newly identified isoform, expressed in the retinal pigment epithelium and monocyte-lineage cells affected by Mitf mutations.
Biochimica et biophysica acta 2002;1574(1):15-23.
2001: Shibahara S; Takeda K; Yasumoto K; Udono T; Watanabe K; Saito H; Takahashi K
Microphthalmia-associated transcription factor (MITF): multiplicity in structure, function, and regulation.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2001;6(1):99-104.
2001: Kitamuro T; Takahashi K; Totsune K; Nakayama M; Murakami O; Hida W; Shirato K; Shibahara S
Differential expression of adrenomedullin and its receptor component, receptor activity modifying protein (RAMP) 2 during hypoxia in cultured human neuroblastoma cells.
Peptides 2001;22(11):1795-801.
2001: Nakayama M; Takahashi K; Komaru T; Fukuchi M; Shioiri H; Sato Ki; Kitamuro T; Shirato K; Yamaguchi T; Suematsu M; Shibahara S
Increased expression of heme oxygenase-1 and bilirubin accumulation in foam cells of rabbit atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(8):1373-7.
2001: Takahashi K; Totsune K; Murakami O; Shibahara S
Expression of urotensin II and urotensin II receptor mRNAs in various human tumor cell lines and secretion of urotensin II-like immunoreactivity by SW-13 adrenocortical carcinoma cells.
Peptides 2001;22(7):1175-9.
2001: Udono T; Takahashi K; Nakayama M; Yoshinoya A; Totsune K; Murakami O; Durlu Y K; Tamai M; Shibahara S
Induction of adrenomedullin by hypoxia in cultured retinal pigment epithelial cells.
Investigative ophthalmology & visual science 2001;42(5):1080-6.
2001: Udono T; Takahashi K; Yasumoto K; Yoshizawa M; Takeda K; Abe T; Tamai M; Shibahara S
Expression of tyrosinase-related protein 2/DOPAchrome tautomerase in the retinoblastoma.
Experimental eye research 2001;72(3):225-34.
2001: Takahashi K; Totsune K; Murakami O; Sone M; Satoh F; Kitamuro T; Noshiro T; Hayashi Y; Sasano H; Shibahara S
Expression of melanin-concentrating hormone receptor messenger ribonucleic acid in tumor tissues of pheochromocytoma, ganglioneuroblastoma, and neuroblastoma.
The Journal of clinical endocrinology and metabolism 2001;86(1):369-74.
2000: Watanabe K; Takeda K; Katori Y; Ikeda K; Oshima T; Yasumoto K; Saito H; Takasaka T; Shibahara S
Expression of the Sox10 gene during mouse inner ear development.
Brain research. Molecular brain research 2000;84(1-2):141-5.
2000: Takahashi K; Yoshinoya A; Murakami O; Totsune K; Shibahara S
Secretion of endothelin-1 and adrenomedullin by SW-13 human adrenocortical carcinoma cells.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S393-4.
2000: Sone M; Takahashi K; Totsune K; Murakami O; Arihara Z; Satoh F; Mouri T; Shibahara S
Expression of endothelin-1 and endothelin receptors in cultured human glioblastoma cells.
Journal of cardiovascular pharmacology 2000;36(5 Suppl 1):S390-2.
2000: Kitamuro T; Takahashi K; Nakayama M; Murakami O; Hida W; Shirato K; Shibahara S
Induction of adrenomedullin during hypoxia in cultured human glioblastoma cells.
Journal of neurochemistry 2000;75(5):1826-33.
2000: Takahashi K; Yoshinoya A; Arihara Z; Murakami O; Totsune K; Sone M; Sasano H; Shibahara S
Regional distribution of immunoreactive prolactin-releasing peptide in the human brain.
Peptides 2000;21(10):1551-5.
2000: Amae S; Yasumoto K; Takeda K; Udono T; Takahashi K; Shibahara S
Identification of a composite enhancer of the human tyrosinase-related protein 2/DOPAchrome tautomerase gene.
Biochimica et biophysica acta 2000;1492(2-3):505-8.
2000: Nakayama M; Takahashi K; Kitamuro T; Murakami O; Shirato K; Shibahara S
Transcriptional control of adrenomedullin induction by phorbol ester in human monocytic leukemia cells.
European journal of biochemistry / FEBS 2000;267(12):3559-66.
2000: Udono T; Takahashi K; Nakayama M; Murakami O; Durlu Y K; Tamai M; Shibahara S
Adrenomedullin in cultured human retinal pigment epithelial cells.
Investigative ophthalmology & visual science 2000;41(7):1962-70.
2000: Nakayama M; Takahashi K; Kitamuro T; Yasumoto K; Katayose D; Shirato K; Fujii-Kuriyama Y; Shibahara S
Repression of heme oxygenase-1 by hypoxia in vascular endothelial cells.
Biochemical and biophysical research communications 2000;271(3):665-71.
2000: Takeda K; Yasumoto K; Takada R; Takada S; Watanabe K; Udono T; Saito H; Takahashi K; Shibahara S
Induction of melanocyte-specific microphthalmia-associated transcription factor by Wnt-3a.
The Journal of biological chemistry 2000;275(19):14013-6.
2000: Udono T; Totsune K; Takahashi K; Abe T; Sato M; Shibahara S; Tamai M
Increased expression of adrenomedullin mRNA in the tissues of intraocular and orbital tumors.
American journal of ophthalmology 2000;129(4):555-6.
2000: Udono T; Yasumoto K; Takeda K; Amae S; Watanabe K; Saito H; Fuse N; Tachibana M; Takahashi K; Tamai M; Shibahara S
Structural organization of the human microphthalmia-associated transcription factor gene containing four alternative promoters.
Biochimica et biophysica acta 2000;1491(1-3):205-19.
2000: Takahashi K; Yoshinoya A; Murakami O; Totsune K; Shibahara S
Production and secretion of two vasoactive peptides, adrenomedullin and endothelin-1, by cultured human adrenocortical carcinoma cells.
Peptides 2000;21(2):251-6.
2000: Takahashi K; Nakayama M; Totsune K; Murakami O; Sone M; Kitamuro T; Yoshinoya A; Shibahara S
Increased secretion of adrenomedullin from cultured human astrocytes by cytokines.
Journal of neurochemistry 2000;74(1):99-103.
2000: Shibahara S; Yasumoto K; Amae S; Udono T; Watanabe K; Saito H; Takeda K
Regulation of pigment cell-specific gene expression by MITF.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 2000;13 Suppl 8():98-102.
1999: Udono T; Takahashi K; Takano S; Shibahara S; Tamai M
Elevated adrenomedullin in the vitreous of patients with proliferative vitreoretinopathy.
American journal of ophthalmology 1999;128(6):765-7.
1999: Fuse N; Yasumoto K i; Takeda K; Amae S; Yoshizawa M; Udono T; Takahashi K; Tamai M; Tomita Y; Tachibana M; Shibahara S
Molecular cloning of cDNA encoding a novel microphthalmia-associated transcription factor isoform with a distinct amino-terminus.
Journal of biochemistry 1999;126(6):1043-51.
1999: Shibahara S; Yasumoto K; Amae S; Fuse N; Udono T; Takahashi K
Implications of isoform multiplicity of microphthalmia-associated transcription factor in the pathogenesis of auditory-pigmentary syndromes.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1999;4(2):101-4.
1999: Nakayama M; Takahashi K; Murakami O; Murakami H; Sasano H; Shirato K; Shibahara S
Adrenomedullin in monocytes and macrophages: possible involvement of macrophage-derived adrenomedullin in atherogenesis.
Clinical science (London, England : 1979) 1999;97(2):247-51.
1999: Hara E; Takahashi K; Takeda K; Nakayama M; Yoshizawa M; Fujita H; Shirato K; Shibahara S
Induction of heme oxygenase-1 as a response in sensing the signals evoked by distinct nitric oxide donors.
Biochemical pharmacology 1999;58(2):227-36.
1999: Takahashi K; Nakayama M; Takeda K; Fujia H; Shibahara S
Suppression of heme oxygenase-1 mRNA expression by interferon-gamma in human glioblastoma cells.
Journal of neurochemistry 1999;72(6):2356-61.
1999: Yasumoto K; Shibahara S
[Isoform multiplicity of microphthalmia-associated transcription factor]
Seikagaku. The Journal of Japanese Biochemical Society 1999;71(1):61-4.
1999: Nakayama M; Takahashi K; Murakami O; Yanai M; Sasaki H; Shirato K; Shibahara S
Production and secretion of adrenomedullin in cultured human alveolar macrophages.
Peptides 1999;20(9):1123-5.
1999: Nakayama M; Takahashi K; Murakami O; Shirato K; Shibahara S
Induction of adrenomedullin by hypoxia in cultured human coronary artery endothelial cells.
Peptides 1999;20(6):769-72.
1998: Yasumoto K; Amae S; Udono T; Fuse N; Takeda K; Shibahara S
A big gene linked to small eyes encodes multiple Mitf isoforms: many promoters make light work.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1998;11(6):329-36.
1998: Suzuki H; Takahashi K; Yasumoto K; Amae S; Yoshizawa M; Fuse N; Shibahara S
Role of neurofibromin in modulation of expression of the tyrosinase-related protein 2 gene.
Journal of biochemistry 1998;124(5):992-8.
1998: Amae S; Fuse N; Yasumoto K; Sato S; Yajima I; Yamamoto H; Udono T; Durlu Y K; Tamai M; Takahashi K; Shibahara S
Identification of a novel isoform of microphthalmia-associated transcription factor that is enriched in retinal pigment epithelium.
Biochemical and biophysical research communications 1998;247(3):710-5.
1998: Nakayama M; Takahashi K; Murakami O; Shirato K; Shibahara S
Induction of adrenomedullin by hypoxia and cobalt chloride in human colorectal carcinoma cells.
Biochemical and biophysical research communications 1998;243(2):514-7.
1998: Nakayama M; Takahashi K; Hara E; Murakami O; Totsune K; Sone M; Satoh F; Shibahara S
Production and secretion of two vasoactive peptides, endothelin-1 and adrenomedullin, by a colorectal adenocarcinoma cell line, DLD-1.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S534-6.
1998: Takahashi K; Hara E; Murakami O; Totsune K; Sone M; Satoh F; Kumabe T; Tominaga T; Kayama T; Yoshimoto T; Shibahara S
Production and secretion of endothelin-1 by cultured choroid plexus carcinoma cells.
Journal of cardiovascular pharmacology 1998;31 Suppl 1():S367-9.
1997: Yasumoto K; Shibahara S
Molecular cloning of cDNA encoding a human TFEC isoform, a newly identified transcriptional regulator.
Biochimica et biophysica acta 1997;1353(1):23-31.
1997: Takahashi K; Hara E; Ogawa K; Kimura D; Fujita H; Shibahara S
Possible implications of the induction of human heme oxygenase-1 by nitric oxide donors.
Journal of biochemistry 1997;121(6):1162-8.
1997: Takahashi K; Satoh F; Hara E; Murakami O; Kumabe T; Tominaga T; Kayama T; Yoshimoto T; Shibahara S
Production and secretion of adrenomedullin by cultured choroid plexus carcinoma cells.
Journal of neurochemistry 1997;68(2):726-31.
1997: Yasumoto K; Yokoyama K; Takahashi K; Tomita Y; Shibahara S
Functional analysis of microphthalmia-associated transcription factor in pigment cell-specific transcription of the human tyrosinase family genes.
The Journal of biological chemistry 1997;272(1):503-9.
1997: Takahashi K; Satoh F; Hara E; Sone M; Murakami O; Kayama T; Yoshimoto T; Shibahara S
Production and secretion of adrenomedullin from glial cell tumors and its effects on cAMP production.
Peptides 1997;18(8):1117-24.
1997: Takahashi K; Satoh F; Sone M; Murakami O; Sasano H; Mouri T; Shibahara S
Expression of adrenomedullin mRNA in the human brain and pituitary.
Peptides 1997;18(7):1051-3.
1996: Takahashi K; Hara E; Suzuki H; Sasano H; Shibahara S
Expression of heme oxygenase isozyme mRNAs in the human brain and induction of heme oxygenase-1 by nitric oxide donors.
Journal of neurochemistry 1996;67(2):482-9.
1996: Hara E; Takahashi K; Tominaga T; Kumabe T; Kayama T; Suzuki H; Fujita H; Yoshimoto T; Shirato K; Shibahara S
Expression of heme oxygenase and inducible nitric oxide synthase mRNA in human brain tumors.
Biochemical and biophysical research communications 1996;224(1):153-8.
1996: Okinaga S; Takahashi K; Takeda K; Yoshizawa M; Fujita H; Sasaki H; Shibahara S
Regulation of human heme oxygenase-1 gene expression under thermal stress.
Blood 1996;87(12):5074-84.
1996: Muraosa Y; Takahashi K; Yoshizawa M; Shibahara S
cDNA cloning of a novel protein containing two zinc-finger domains that may function as a transcription factor for the human heme-oxygenase-1 gene.
European journal of biochemistry / FEBS 1996;235(3):471-9.
1996: Fuse N; Yasumoto K; Suzuki H; Takahashi K; Shibahara S
Identification of a melanocyte-type promoter of the microphthalmia-associated transcription factor gene.
Biochemical and biophysical research communications 1996;219(3):702-7.
1995: Takahashi K; Suzuki H; Totsune K; Murakami O; Satoh F; Sone M; Sasano H; Mouri T; Shibahara S
Melanin-concentrating hormone in human and rat.
Neuroendocrinology 1995;61(5):493-8.
1995: Takahashi K; Suzuki H; Hatori M; Abe Y; Kokubun S; Sakurai M; Shibahara S
Reduced expression of neurofibromin in the soft tissue tumours obtained from patients with neurofibromatosis type I.
Clinical science (London, England : 1979) 1995;88(5):581-5.
1995: Suzuki H; Takahashi K; Shibahara S
Evidence for the presence of two amino-terminal isoforms of neurofibromin, a gene product responsible for neurofibromatosis type 1.
The Tohoku journal of experimental medicine 1995;175(4):225-33.
1995: Yasumoto K; Yokoyama K; Shibata K; Tomita Y; Shibahara S
Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene.
Molecular and cellular biology 1995;15(3):1833.
1995: Takeda K; Fujita H; Shibahara S
Differential control of the metal-mediated activation of the human heme oxygenase-1 and metallothionein IIA genes.
Biochemical and biophysical research communications 1995;207(1):160-7.
1994: Yasumoto K; Yokoyama K; Shibata K; Tomita Y; Shibahara S
Microphthalmia-associated transcription factor as a regulator for melanocyte-specific transcription of the human tyrosinase gene.
Molecular and cellular biology 1994;14(12):8058-70.
1994: Suzuki H; Takahashi K; Yasumoto K; Shibahara S
Activation of the tyrosinase gene promoter by neurofibromin.
Biochemical and biophysical research communications 1994;205(3):1984-91.
1994: Takahashi K; Suzuki H; Kayama T; Suzuki Y; Yoshimoto T; Sasano H; Shibahara S
Multiple transcripts of the neurofibromatosis type 1 gene in human brain and in brain tumours.
Clinical science (London, England : 1979) 1994;87(5):481-5.
1994: Yokoyama K; Yasumoto K; Suzuki H; Shibahara S
Cloning of the human DOPAchrome tautomerase/tyrosinase-related protein 2 gene and identification of two regulatory regions required for its pigment cell-specific expression.
The Journal of biological chemistry 1994;269(43):27080-7.
1994: Takeda K; Ishizawa S; Sato M; Yoshida T; Shibahara S
Identification of a cis-acting element that is responsible for cadmium-mediated induction of the human heme oxygenase gene.
The Journal of biological chemistry 1994;269(36):22858-67.
1994: Yokoyama K; Suzuki H; Yasumoto K; Tomita Y; Shibahara S
Molecular cloning and functional analysis of a cDNA coding for human DOPAchrome tautomerase/tyrosinase-related protein-2.
Biochimica et biophysica acta 1994;1217(3):317-21.
1993: Muraosa Y; Shibahara S
Identification of a cis-regulatory element and putative trans-acting factors responsible for 12-O-tetradecanoylphorbol-13-acetate (TPA)-mediated induction of heme oxygenase expression in myelomonocytic cell lines.
Molecular and cellular biology 1993;13(12):7881-91.
1993: Shibahara S; Yoshizawa M; Suzuki H; Takeda K; Meguro K; Endo K
Functional analysis of cDNAs for two types of human heme oxygenase and evidence for their separate regulation.
Journal of biochemistry 1993;113(2):214-8.
1993: Okinaga S; Shibahara S
Identification of a nuclear protein that constitutively recognizes the sequence containing a heat-shock element. Its binding properties and possible function modulating heat-shock induction of the rat heme oxygenase gene.
European journal of biochemistry / FEBS 1993;212(1):167-75.
1993: Shibahara S
Functional analysis of the tyrosinase gene and brown-locus protein gene promoters.
The Journal of investigative dermatology 1993;100(2 Suppl):146S-149S.
1992: Shibahara S
Mutations of the tyrosinase gene in oculocutaneous albinism.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1992;5(5 Pt 2):279-83.
1992: Shibata K; Muraosa Y; Tomita Y; Tagami H; Shibahara S
Identification of a cis-acting element that enhances the pigment cell-specific expression of the human tyrosinase gene.
The Journal of biological chemistry 1992;267(29):20584-8.
1992: Suzuki H; Takahashi K; Kubota Y; Shibahara S
Molecular cloning of a cDNA coding for neurofibromatosis type 1 protein isoform lacking the domain related to ras GTPase-activating protein.
Biochemical and biophysical research communications 1992;187(2):984-90.
1992: Shibata K; Takeda K; Tomita Y; Tagami H; Shibahara S
Downstream region of the human tyrosinase-related protein gene enhances its promoter activity.
Biochemical and biophysical research communications 1992;184(2):568-75.
1992: Shibahara S; Tomita Y; Yoshizawa M; Shibata K; Tagami H
Identification of mutations in the pigment cell-specific gene located at the brown locus in mouse.
Pigment cell research / sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society 1992;Suppl 2():90-5.
1991: Suzuki Y; Suzuki H; Kayama T; Yoshimoto T; Shibahara S
Brain tumors predominantly express the neurofibromatosis type 1 gene transcripts containing the 63 base insert in the region coding for GTPase activating protein-related domain.
Biochemical and biophysical research communications 1991;181(3):955-61.
1991: Shibahara S; Taguchi H; Muller R M; Shibata K; Cohen T; Tomita Y; Tagami H
Structural organization of the pigment cell-specific gene located at the brown locus in mouse. Its promoter activity and alternatively spliced transcript.
The Journal of biological chemistry 1991;266(24):15895-901.
1991: Takeda A; Matsunaga J; Tomita Y; Tagami H; Shibahara S
Nucleotide sequence of the putative human tyrosinase pseudogene.
The Tohoku journal of experimental medicine 1991;163(4):295-7.

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