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Tatsuhiro Shibata

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Noriyuki Kitagawa; Akiko Kokubu; Tomoo Kosuge; Shinichi Miyagawa; Hidenori Ojima; Hiroko Shimizu; Takuya Shirakihara; Yasushi Totoki; Tomoko Urushidate; Tatsuhiro Shibata
Downregulation of the microRNA biogenesis components and its association with poor prognosis in hepatocellular carcinoma.
Akihiko Yoshida; Koji Tsuta; Susumu Wakai; Yasuhito Arai; Hisao Asamura; Koh Furuta; Takashi Kohno; Tatsuhiro Shibata; Yoko Shimada; Hitoshi Tsuda
ROS1-rearranged lung cancer: a clinicopathologic and molecular study of 15 surgical cases.
Yasuhito Arai; Hisao Asamura; Natsuko Hama; Fumie Hosoda; Takashi Kohno; Michihiro Mutoh; Hiromi Nakamura; Hiroyuki Takahashi; Yasushi Totoki; Hitoshi Tsuda; Koji Tsuta; Akihiko Yoshida; Tatsuhiro Shibata
Mouse model for ROS1-rearranged lung cancer.

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2013: Noriyuki Kitagawa; Akiko Kokubu; Tomoo Kosuge; Shinichi Miyagawa; Hidenori Ojima; Hiroko Shimizu; Takuya Shirakihara; Yasushi Totoki; Tomoko Urushidate; Tatsuhiro Shibata
Downregulation of the microRNA biogenesis components and its association with poor prognosis in hepatocellular carcinoma.
Cancer science 2013;104(5):543-51.
2013: Akihiko Yoshida; Koji Tsuta; Susumu Wakai; Yasuhito Arai; Hisao Asamura; Koh Furuta; Takashi Kohno; Tatsuhiro Shibata; Yoko Shimada; Hitoshi Tsuda
ROS1-rearranged lung cancer: a clinicopathologic and molecular study of 15 surgical cases.
The American journal of surgical pathology 2013;37(4):554-62.
2013: Yasuhito Arai; Hisao Asamura; Natsuko Hama; Fumie Hosoda; Takashi Kohno; Michihiro Mutoh; Hiromi Nakamura; Hiroyuki Takahashi; Yasushi Totoki; Hitoshi Tsuda; Koji Tsuta; Akihiko Yoshida; Tatsuhiro Shibata
Mouse model for ROS1-rearranged lung cancer.
PloS one 2013;8(2):e56010.
2012: Tatsuhiro Shibata
Cancer genomics and pathology: all together now.
Pathology international 2012;62(10):647-59.
2012: Makiko Ono; Tatsuhiro Shibata; Chikako Shimizu; Yuichi Takiguchi; Kenji Tamura; Hideki Tanzawa; Hitoshi Tsuda; Harukaze Yamamoto; Sohei Yamamoto; Kan Yonemori; Masashi Ando; Taizo Hirata; Noriyuki Katsumata; Takayuki Kinoshita; Yasuhiro Fujiwara
Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer.
Breast cancer research and treatment 2012;132(3):793-805.
2012: Takashi Kohno; Takao Nammo; Seishi Ogawa; Hideaki Ogiwara; Takahiro Oike; Hirokazu Okayama; Hiromi Sakamoto; Aaron J Schetter; Ikuo Sekine; Yasuhito Arai; Suenori Chiku; Masato Enari; Koh Furuta; Curtis C Harris; Aage Haugen; Masaki Hiramoto; Hitoshi Ichikawa; Reika Iwakawa; Yoko Shimada; Vidar Skaug; Yasushi Totoki; Hitoshi Tsuda; Koji Tsuta; Shun-Ichi Watanabe; Itaru Yamanaka; Kazuki Yasuda; Jun Yokota; Teruhiko Yoshida; Tatsuhiro Shibata
KIF5B-RET fusions in lung adenocarcinoma.
Nature medicine 2012;18(3):375-7.
2012: Akihiko Yoshida; Hitoshi Tsuda; Tetsuo Ushiku; Yasuo Beppu; Masashi Fukayama; Toru Motoi; Tatsuhiro Shibata
MDM2 and CDK4 immunohistochemical coexpression in high-grade osteosarcoma: correlation with a dedifferentiated subtype.
The American journal of surgical pathology 2012;36(3):423-31.
2012: Linghua Wang; Shogo Yamamoto; Hiroki Yamaue; Seiko Hirono; Takayuki Isagawa; Minoru Isomura; Yae Kanai; Atsushi Kaneda; Tokuichi Kawaguchi; Yoshio Miki; Satsuki Murayama-Hosokawa; Genta Nagae; Koichi Nagasaki; Tetsuo Noda; Akio Saiura; Hiromi Sakamoto; Fei Sang; Tatsuhiro Shibata; Kohtaro Sonoda; Minoru Sugawara; Kenji Tatsuno; Y Totoki; Shuichi Tsutsumi; Hiroki Ueda; Hiroyuki Aburatani
Whole-exome sequencing of human pancreatic cancers and characterization of genomic instability caused by MLH1 haploinsufficiency and complete deficiency.
Genome research 2012;22(2):208-19.
2012: Hirokazu Okayama; Hiromi Sakamoto; Akinori Sarai; Tatsuhiro Shibata; Yoko Shimada; Kouya Shiraishi; Seiichi Takenoshita; Koji Tsuta; Shun-ichi Watanabe; Rui Yamaguchi; Seiichiro Yamamoto; Koh Furuta; Noriko Gotoh; Yuko Ishii; Reika Iwakawa; Shuichi Kawano; Takashi Kohno; Kensuke Kumamoto; Satoru Miyano; Hideaki Mizuno; Jun Yokota
Identification of genes upregulated in ALK-positive and EGFR/KRAS/ALK-negative lung adenocarcinomas.
Cancer research 2012;72(1):100-11.
2011: Takahiro Hasebe; Takashi Hojo; Motoki Iwasaki; Takayuki Kinoshita; Yuko Sasajima; Tatsuhiro Shibata; Sadako Akashi-Tanaka; Hitoshi Tsuda
Prognostic significance of mitotic figures in metastatic mammary ductal carcinoma to the lymph nodes.
Human pathology 2011;42(12):1823-32.
2011: Akihiko Yoshida; Koji Tsuta; Hisao Asamura; Masashi Fukayama; Koh Furuta; Thomas M Grogan; Yutaka Hatanaka; Takashi Kohno; Hiroaki Nitta; Ikuo Sekine; Tatsuhiro Shibata; Hitoshi Tsuda
Bright-field dual-color chromogenic in situ hybridization for diagnosing echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase-positive lung adenocarcinomas.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2011;6(10):1677-86.
2011: Takahiro Hasebe; Takashi Hojo; Motoki Iwasaki; Takayuki Kinoshita; Tatsuhiro Shibata; Sadako Akashi-Tanaka; Hitoshi Tsuda
Important histologic outcome predictors for patients with invasive ductal carcinoma of the breast.
The American journal of surgical pathology 2011;35(10):1484-97.
2011: Tatsuhiro Shibata; Yuji Tachimori; Yuki Yoshimatsu; Kazuhiko Aoyagi; Tohru Kiyono; Akiko Kokubu; Ryoji Kushima; Mako Narisawa-Saito; Shigeru Saito; Hiroki Sasaki; Masayuki Yamamoto
NRF2 mutation confers malignant potential and resistance to chemoradiation therapy in advanced esophageal squamous cancer.
Neoplasia (New York, N.Y.) 2011;13(9):864-73.
2011: T Hasebe; T Hojo; Motoki Iwasaki; T Kinoshita; Y Sasajima; Tatsuhiro Shibata; S Akashi-Tanaka; Hitoshi Tsuda
Modified primary tumour/vessel tumour/nodal tumour classification for patients with invasive ductal carcinoma of the breast.
British journal of cancer 2011;105(5):698-708.
2011: Takahiro Hasebe; Takashi Hojo; Motoki Iwasaki; Takayuki Kinoshita; Yuko Sasajima; Tatsuhiro Shibata; Chikako Shimizu; Sadako Akashi-Tanaka; Masashi Andoh; Yasuhiro Fujiwara; Hitoshi Tsuda
Atypical tumor-stromal fibroblasts in invasive ductal carcinomas of the breast treated with neoadjuvant therapy.
Human pathology 2011;42(7):998-1006.
2011: Akihiko Yoshida; Koji Tsuta; Shun-ichi Watanabe; Ikuo Sekine; Masashi Fukayama; Hitoshi Tsuda; Koh Furuta; Tatsuhiro Shibata
Frequent ALK rearrangement and TTF-1/p63 co-expression in lung adenocarcinoma with signet-ring cell component.
Lung cancer (Amsterdam, Netherlands) 2011;72(3):309-15.
2011: Naotaka Nishiyama; Eri Arai; Ryo Nagashio; Hiroyuki Fujimoto; Fumie Hosoda; Tatsuhiro Shibata; Taiji Tsukamoto; Sana Yokoi; Issei Imoto; Johji Inazawa; Yae Kanai
Copy number alterations in urothelial carcinomas: their clinicopathological significance and correlation with DNA methylation alterations.
Carcinogenesis 2011;32(4):462-9.
2011: Takuya Shirakihara; Kana Horiguchi; Keiji Miyazawa; Shogo Ehata; Tatsuhiro Shibata; Ikuo Morita; Kohei Miyazono; Masao Saitoh
TGF-β regulates isoform switching of FGF receptors and epithelial-mesenchymal transition.
The EMBO journal 2011;30(4):783-95.
2011: Eri Arai; Saori Wakai-Ushijima; Hiroyuki Fujimoto; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Sana Yokoi; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Yae Kanai
Genome-wide DNA methylation profiles in renal tumors of various histological subtypes and non-tumorous renal tissues.
Pathobiology : journal of immunopathology, molecular and cellular biology 2011;78(1):1-9.
2011: Masahiro Gotoh; Eri Arai; Saori Wakai-Ushijima; Nobuyoshi Hiraoka; Tomoo Kosuge; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Sana Yokoi; Issei Imoto; Johji Inazawa; Yae Kanai
Diagnosis and prognostication of ductal adenocarcinomas of the pancreas based on genome-wide DNA methylation profiling by bacterial artificial chromosome array-based methylated CpG island amplification.
Journal of biomedicine & biotechnology 2011;2011():780836.
2010: Izumi Nakahara; Mamiko Miyamoto; Tatsuhiro Shibata; Sadako Akashi-Tanaka; Takayuki Kinoshita; Kaoru Mogushi; Kohtaro Oda; Masaya Ueno; Nobuyuki Takakura; Hiroshi Mizushima; Hiroshi Tanaka; Tsutomu Ohta
Up-regulation of PSF1 promotes the growth of breast cancer cells.
Genes to cells : devoted to molecular & cellular mechanisms 2010;15(10):1015-24.
2010: Akihiko Yoshida; Tetsuo Ushiku; Toru Motoi; Tatsuhiro Shibata; Yasuo Beppu; Masashi Fukayama; Hitoshi Tsuda
Immunohistochemical analysis of MDM2 and CDK4 distinguishes low-grade osteosarcoma from benign mimics.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(9):1279-88.
2010: Nao Okada; Takahiro Hasebe; Motoki Iwasaki; Nobuko Tamura; Sadako Akashi-Tanaka; Takashi Hojo; Tatsuhiro Shibata; Yuko Sasajima; Yae Kanai; Takayuki Kinoshita
Metaplastic carcinoma of the breast.
Human pathology 2010;41(7):960-70.
2010: Takahiro Hasebe; Motoki Iwasaki; Sadako Akashi-Tanaka; Takashi Hojo; Tatsuhiro Shibata; Yuko Sasajima; Takayuki Kinoshita; Hitoshi Tsuda
p53 expression in tumor-stromal fibroblasts forming and not forming fibrotic foci in invasive ductal carcinoma of the breast.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(5):662-72.
2010: Takahiro Hasebe; Nao Okada; Motoki Iwasaki; Sadako Akashi-Tanaka; Takashi Hojo; Tatsuhiro Shibata; Yuko Sasajima; H Tsuda; Takayuki Kinoshita
Grading system for lymph vessel tumor emboli: significant outcome predictor for invasive ductal carcinoma of the breast.
Human pathology 2010;41(5):706-15.
2010: Takahiro Hasebe; Nobuko Tamura; Motoki Iwasaki; Nao Okada; Sadako Akashi-Tanaka; Takashi Hojo; Chikako Shimizu; Masashi Adachi; Yasuhiro Fujiwara; Tatsuhiro Shibata; Yuko Sasajima; Histoshi Tsuda; Takayuki Kinoshita
Grading system for lymph vessel tumor emboli: significant outcome predictor for patients with invasive ductal carcinoma of the breast who received neoadjuvant therapy.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2010;23(4):581-92.
2010: Hidenori Ojima; Daitaro Yoshikawa; Yoshihiro Ino; Hiroko Shimizu; Masashi Miyamoto; Akiko Kokubu; Nobuyoshi Hiraoka; Noriaki Morofuji; Tadashi Kondo; Hiroaki Onaya; Takuji Okusaka; Kazuaki Shimada; Yoshihiro Sakamoto; Minoru Esaki; Satoshi Nara; Tomoo Kosuge; Setsuo Hirohashi; Yae Kanai; Tatsuhiro Shibata
Establishment of six new human biliary tract carcinoma cell lines and identification of MAGEH1 as a candidate biomarker for predicting the efficacy of gemcitabine treatment.
Cancer science 2010;101(4):882-8.
2010: Takahiro Hasebe; Nobuko Tamura; Nao Okada; Takashi Hojo; Sadako Akashi-Tanaka; Chikako Shimizu; Histoshi Tsuda; Tatsuhiro Shibata; Yuko Sasajima; Motoki Iwasaki; Takayuki Kinoshita
p53 expression in tumor-stromal fibroblasts is closely associated with the nodal metastasis and outcome of patients with invasive ductal carcinoma who received neoadjuvant therapy.
Human pathology 2010;41(2):262-70.
2010: Naotaka Nishiyama; Eri Arai; Yoshitomo Chihara; Hiroyuki Fujimoto; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Taiji Tsukamoto; Sana Yokoi; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Yae Kanai
Genome-wide DNA methylation profiles in urothelial carcinomas and urothelia at the precancerous stage.
Cancer science 2010;101(1):231-40.
2009: Eri Arai; Saori Ushijima; Masahiro Gotoh; Hidenori Ojima; Tomoo Kosuge; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Sana Yokoi; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Yae Kanai
Genome-wide DNA methylation profiles in liver tissue at the precancerous stage and in hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2009;125(12):2854-62.
2009: Takashi Kubo; Yukie Kuroda; Hiroko Shimizu; Akiko Kokubu; Naoko Okada; Fumie Hosoda; Yasuhito Arai; Yu Nakamura; Hirokazu Taniguchi; Kazuyoshi Yanagihara; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Tatsuhiro Shibata
Resequencing and copy number analysis of the human tyrosine kinase gene family in poorly differentiated gastric cancer.
Carcinogenesis 2009;30(11):1857-64.
2009: Yu Nakamura; Toshiro Migita; Fumie Hosoda; Naoko Okada; Masahiro Gotoh; Yasuhito Arai; Michiyo Fukushima; Misao Ohki; Satoshi Miyata; Kengo Takeuchi; Issei Imoto; Hitoshi Katai; Toshiharu Yamaguchi; Johji Inazawa; Setsuo Hirohashi; Yuichi Ishikawa; Tatsuhiro Shibata
Krüppel-like factor 12 plays a significant role in poorly differentiated gastric cancer progression.
International journal of cancer. Journal international du cancer 2009;125(8):1859-67.
2009: Tatsuhiro Shibata; Akiko Kokubu; Koji Tsuta; Setsuo Hirohashi
Oncogenic mutation of PIK3CA in small cell lung carcinoma: a potential therapeutic target pathway for chemotherapy-resistant lung cancer.
Cancer letters 2009;283(2):203-11.
2009: D Yoshikawa; Hidenori Ojima; Akiko Kokubu; T Ochiya; S Kasai; Setsuo Hirohashi; Tatsuhiro Shibata
Vandetanib (ZD6474), an inhibitor of VEGFR and EGFR signalling, as a novel molecular-targeted therapy against cholangiocarcinoma.
British journal of cancer 2009;100(8):1257-66.
2009: Eri Arai; Saori Ushijima; Hiroyuki Fujimoto; Fumie Hosoda; Tatsuhiro Shibata; Tadashi Kondo; Sana Yokoi; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Yae Kanai
Genome-wide DNA methylation profiles in both precancerous conditions and clear cell renal cell carcinomas are correlated with malignant potential and patient outcome.
Carcinogenesis 2009;30(2):214-21.
2008: Tatsuhiro Shibata; Akiko Kokubu; Masahiro Gotoh; Hidenori Ojima; Tsutomu Ohta; Masayuki Yamamoto; Setsuo Hirohashi
Genetic alteration of Keap1 confers constitutive Nrf2 activation and resistance to chemotherapy in gallbladder cancer.
Gastroenterology 2008;135(4):1358-1368, 1368.e1-4.
2008: Ayako Suzuki; Tatsuhiro Shibata; Yutaka Shimada; Yoshinori Murakami; Akira Horii; Keiko Shiratori; Setsuo Hirohashi; Johji Inazawa; Issei Imoto
Identification of SMURF1 as a possible target for 7q21.3-22.1 amplification detected in a pancreatic cancer cell line by in-house array-based comparative genomic hybridization.
Cancer science 2008;99(5):986-94.
2008: Tsutomu Ohta; Kumiko Iijima; Mamiko Miyamoto; Izumi Nakahara; Hiroshi Tanaka; Makiko Ohtsuji; Takafumi Suzuki; Akira Kobayashi; Jun Yokota; Tokuki Sakiyama; Tatsuhiro Shibata; Masayuki Yamamoto; Setsuo Hirohashi
Loss of Keap1 function activates Nrf2 and provides advantages for lung cancer cell growth.
Cancer research 2008;68(5):1303-9.
2007: Yukihiro Yoshida; Akiko Kokubu; Kenji Suzuki; Hidehiko Kuribayashi; Koji Tsuta; Yoshihiro Matsuno; Masahiko Kusumoto; Yae Kanai; Hisao Asamura; Setsuo Hirohashi; Tatsuhiro Shibata
Molecular markers and changes of computed tomography appearance in lung adenocarcinoma with ground-glass opacity.
Japanese journal of clinical oncology 2007;37(12):907-12.
2007: Hiroto Katoh; Hidenori Ojima; Akiko Kokubu; Shigeru Saito; Tadashi Kondo; Tomoo Kosuge; Fumie Hosoda; Issei Imoto; Johji Inazawa; Setsuo Hirohashi; Tatsuhiro Shibata
Genetically distinct and clinically relevant classification of hepatocellular carcinoma: putative therapeutic targets.
Gastroenterology 2007;133(5):1475-86.
2007: Panayiotis Loukopoulos; Tatsuhiro Shibata; Hiroto Katoh; Akiko Kokubu; Michiie Sakamoto; Ken Yamazaki; Tomoo Kosuge; Yae Kanai; Fumie Hosoda; Issei Imoto; Misao Ohki; Johji Inazawa; Setsuo Hirohashi
Genome-wide array-based comparative genomic hybridization analysis of pancreatic adenocarcinoma: identification of genetic indicators that predict patient outcome.
Cancer science 2007;98(3):392-400.
2006: Hiroto Katoh; Tatsuhiro Shibata; Akiko Kokubu; Hidenori Ojima; Tomoo Kosuge; Yae Kanai; Setsuo Hirohashi
Genetic inactivation of the APC gene contributes to the malignant progression of sporadic hepatocellular carcinoma: a case report.
Genes, chromosomes & cancer 2006;45(11):1050-7.
2006: Tatsuhiro Shibata; Setsuo Hirohashi
[E-cadherin cell adhesion system in human cancer].
Seikagaku. The Journal of Japanese Biochemical Society 2006;78(7):647-56.
2006: Issei Imoto; Hiroyuki Izumi; Sana Yokoi; Hiroshi Hosoda; Tatsuhiro Shibata; Fumie Hosoda; Misao Ohki; Setsuo Hirohashi; Johji Inazawa
Frequent silencing of the candidate tumor suppressor PCDH20 by epigenetic mechanism in non-small-cell lung cancers.
Cancer research 2006;66(9):4617-26.
2006: Yu Takahashi; Nobuyoshi Hiraoka; Kaoru Onozato; Tatsuhiro Shibata; Tomoo Kosuge; Yuji Nimura; Yae Kanai; Setsuo Hirohashi
Solid-pseudopapillary neoplasms of the pancreas in men and women: do they differ?
Virchows Archiv : an international journal of pathology 2006;448(5):561-9.
2006: Hiroto Katoh; Tatsuhiro Shibata; Akiko Kokubu; Hidenori Ojima; Masashi Fukayama; Yae Kanai; Setsuo Hirohashi
Epigenetic instability and chromosomal instability in hepatocellular carcinoma.
The American journal of pathology 2006;168(4):1375-84.
2005: Hiroto Katoh; Tatsuhiro Shibata; Akiko Kokubu; Hidenori Ojima; Panayiotis Loukopoulos; Yae Kanai; Tomoo Kosuge; Masashi Fukayama; Tadashi Kondo; Michiie Sakamoto; Fumie Hosoda; Misao Ohki; Issei Imoto; Johji Inazawa; Setsuo Hirohashi
Genetic profile of hepatocellular carcinoma revealed by array-based comparative genomic hybridization: identification of genetic indicators to predict patient outcome.
Journal of hepatology 2005;43(5):863-74.
2005: Wei-Xia Peng; Tatsuhiro Shibata; Hiroto Katoh; Akiko Kokubu; Yoshihiro Matsuno; Hisao Asamura; Ryosuke Tsuchiya; Yae Kanai; Fumie Hosoda; Tokuki Sakiyama; Misao Ohki; Issei Imoto; Johji Inazawa; Setsuo Hirohashi
Array-based comparative genomic hybridization analysis of high-grade neuroendocrine tumors of the lung.
Cancer science 2005;96(10):661-7.
2005: Toshimi Takano; Yuichiro Ohe; Hiromi Sakamoto; Koji Tsuta; Yoshihiro Matsuno; Ukihide Tateishi; Seiichiro Yamamoto; Hiroshi Nokihara; Noboru Yamamoto; Ikuo Sekine; Hideo Kunitoh; Tatsuhiro Shibata; Tokuki Sakiyama; Teruhiko Yoshida; Tomohide Tamura
Epidermal growth factor receptor gene mutations and increased copy numbers predict gefitinib sensitivity in patients with recurrent non-small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(28):6829-37.
2005: Yukihiro Yoshida; Tatsuhiro Shibata; Akiko Kokubu; Koji Tsuta; Yoshihiro Matsuno; Yae Kanai; Hisao Asamura; Ryosuke Tsuchiya; Setsuo Hirohashi
Mutations of the epidermal growth factor receptor gene in atypical adenomatous hyperplasia and bronchioloalveolar carcinoma of the lung.
Lung cancer (Amsterdam, Netherlands) 2005;50(1):1-8.
2005: Tatsuhiro Shibata; Satomi Uryu; Akiko Kokubu; Fumie Hosoda; Misao Ohki; Tokuki Sakiyama; Yoshihiro Matsuno; Ryosuke Tsuchiya; Yae Kanai; Tadashi Kondo; Issei Imoto; Johji Inazawa; Setsuo Hirohashi
Genetic classification of lung adenocarcinoma based on array-based comparative genomic hybridization analysis: its association with clinicopathologic features.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(17):6177-85.
2005: Hiroyuki Izumi; Jun-Ichiro Inoue; Sana Yokoi; Hiroshi Hosoda; Tatsuhiro Shibata; Makoto Sunamori; Setsuo Hirohashi; Johji Inazawa; Issei Imoto
Frequent silencing of DBC1 is by genetic or epigenetic mechanisms in non-small cell lung cancers.
Human molecular genetics 2005;14(8):997-1007.
2004: Shigeki Sekine; T Takata; Tatsuhiro Shibata; M Mori; Y Morishita; M Noguchi; T Uchida; Yae Kanai; Setsuo Hirohashi
Expression of enamel proteins and LEF1 in adamantinomatous craniopharyngioma: evidence for its odontogenic epithelial differentiation.
Histopathology 2004;45(6):573-9.
2004: Shigeki Sekine; Tadakazu Shimoda; Satoshi Nimura; Yukihiro Nakanishi; Takayuki Akasu; Hitoshi Katai; Takuji Gotoda; Tatsuhiro Shibata; Michiie Sakamoto; Setsuo Hirohashi
High-grade dysplasia associated with fundic gland polyposis in a familial adenomatous polyposis patient, with special reference to APC mutation profiles.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(11):1421-6.
2004: Panayiotis Loukopoulos; Kengo Kanetaka; Masaaki Takamura; Tatsuhiro Shibata; Michiie Sakamoto; Setsuo Hirohashi
Orthotopic transplantation models of pancreatic adenocarcinoma derived from cell lines and primary tumors and displaying varying metastatic activity.
Pancreas 2004;29(3):193-203.
2004: Itaru Sonoda; Issei Imoto; Jun-Ichiro Inoue; Tatsuhiro Shibata; Yutaka Shimada; Koei Chin; Masayuki Imamura; Teruo Amagasa; Joe Gray; Setsuo Hirohashi; Johji Inazawa
Frequent silencing of low density lipoprotein receptor-related protein 1B (LRP1B) expression by genetic and epigenetic mechanisms in esophageal squamous cell carcinoma.
Cancer research 2004;64(11):3741-7.
2004: Tatsuhiro Shibata; Akiko Kokubu; Shigeki Sekine; Yae Kanai; Setsuo Hirohashi
Cytoplasmic p120ctn regulates the invasive phenotypes of E-cadherin-deficient breast cancer.
The American journal of pathology 2004;164(6):2269-78.
2003: Shigeki Sekine; Sunao Sato; Takashi Takata; Yasuo Fukuda; Takeshi Ishida; Mitsunobu Kishino; Tatsuhiro Shibata; Yae Kanai; Setsuo Hirohashi
Beta-catenin mutations are frequent in calcifying odontogenic cysts, but rare in ameloblastomas.
The American journal of pathology 2003;163(5):1707-12.
2003: Tatsuhiro Shibata; Makoto Chuma; Akiko Kokubu; Michiie Sakamoto; Setsuo Hirohashi
EBP50, a beta-catenin-associating protein, enhances Wnt signaling and is over-expressed in hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2003;38(1):178-86.
2003: Shigeki Sekine; Tatsuhiro Shibata; Yoshihiro Matsuno; Arafumi Maeshima; Genichiro Ishii; Michiie Sakamoto; Setsuo Hirohashi
Beta-catenin mutations in pulmonary blastomas: association with morule formation.
The Journal of pathology 2003;200(2):214-21.
2002: Shigeki Sekine; Tatsuhiro Shibata; Akiko Kokubu; Yukio Morishita; Masayuki Noguchi; Yukihiro Nakanishi; Michiie Sakamoto; Setsuo Hirohashi
Craniopharyngiomas of adamantinomatous type harbor beta-catenin gene mutations.
The American journal of pathology 2002;161(6):1997-2001.
2002: Shigeki Sekine; Tatsuhiro Shibata; Michiie Sakamoto; Setsuo Hirohashi
Target disruption of the mutant beta-catenin gene in colon cancer cell line HCT116: preservation of its malignant phenotype.
Oncogene 2002;21(38):5906-11.
2002: Shigeki Sekine; Tatsuhiro Shibata; Yuko Yamauchi; Yukihiro Nakanishi; Tadakazu Shimoda; Michiie Sakamoto; Setsuo Hirohashi
Beta-catenin mutations in sporadic fundic gland polyps.
Virchows Archiv : an international journal of pathology 2002;440(4):381-6.
1997: Yoshiaki Ito; Kazuhiko Yamasaki; Junji Iwahara; Takaho Terada; Akira Kamiya; Mikako Shirouzu; Yutaka Muto; Gota Kawai; Shigeyuki Yokoyama; E D Laue; M Wälchli; Tatsuhiro Shibata; Susumu Nishimura; T Miyazawa
Regional polysterism in the GTP-bound form of the human c-Ha-Ras protein.
Biochemistry 1997;36(30):9109-19.