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Nobuyoshi Shimizu

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Atsushi Shimizu; Nobuyoshi Shimizu
Dual promoter expression system with insulator ensures a stringent tissue-specific regulation of two reporter genes in the transgenic fish.
Susumu Mitsuyama; Nobuyoshi Shimizu
CancerProView: a graphical image database of cancer-related genes and proteins.
Shigeshi Ono; Michiie Sakamoto; Nobuyoshi Shimizu; Masahiro Shinoda; Atsushi Takayanagi; Minoru Tanabe; Arno W Tilles; Martin L Yarmush; Sadakazu Aiso; Tomohiro Chiba; Wenlin Du; Taizo Hibi; Osamu Itano; Shigeyuki Kawachi; Minoru Kitago; Kenji Matsumoto; Hideaki Obara; Yuko Kitagawa
Suppressive effects of interleukin-18 on liver function in rat liver allografts.

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All Publications

2013: Atsushi Shimizu; Nobuyoshi Shimizu
Dual promoter expression system with insulator ensures a stringent tissue-specific regulation of two reporter genes in the transgenic fish.
Transgenic research 2013;22(2):435-44.
2012: Susumu Mitsuyama; Nobuyoshi Shimizu
CancerProView: a graphical image database of cancer-related genes and proteins.
Genomics 2012;100(2):81-92.
2012: Shigeshi Ono; Michiie Sakamoto; Nobuyoshi Shimizu; Masahiro Shinoda; Atsushi Takayanagi; Minoru Tanabe; Arno W Tilles; Martin L Yarmush; Sadakazu Aiso; Tomohiro Chiba; Wenlin Du; Taizo Hibi; Osamu Itano; Shigeyuki Kawachi; Minoru Kitago; Kenji Matsumoto; Hideaki Obara; Yuko Kitagawa
Suppressive effects of interleukin-18 on liver function in rat liver allografts.
The Journal of surgical research 2012;176(1):293-300.
2011: Naoko Wada; Koji Nishifuji; Taketo Yamada; Jun Kudoh; Nobuyoshi Shimizu; Mitsuru Matsumoto; Leena Peltonen; Seiho Nagafuchi; Masayuki Amagai
Aire-dependent thymic expression of desmoglein 3, the autoantigen in pemphigus vulgaris, and its role in T-cell tolerance.
The Journal of investigative dermatology 2011;131(2):410-7.
2010: Shinsei Minoshima; Masafumi Ohtsubo; Nobuyoshi Shimizu
[Databases for mutations in human diseases].
Nihon rinsho. Japanese journal of clinical medicine 2010;68 Suppl 8():150-8.
2010: Katsuhiro Hosono; Setsuko Noda; Atsushi Shimizu; Nobuo Nakanishi; Masafumi Ohtsubo; Nobuyoshi Shimizu; Shinsei Minoshima
YPEL5 protein of the YPEL gene family is involved in the cell cycle progression by interacting with two distinct proteins RanBPM and RanBP10.
Genomics 2010;96(2):102-11.
2010: Tomotaka Sato; Atsushi Takayanagi; Keisuke Nagao; Nobuhiro Tomatsu; Toshifumi Fukui; Masahiro Kawaguchi; Jun Kudoh; Masayuki Amagai; Nobuko Yamamoto; Nobuyoshi Shimizu
Simple PCR-based DNA microarray system to identify human pathogenic fungi in skin.
Journal of clinical microbiology 2010;48(7):2357-64.
2010: Takashi Kawamura; Masafumi Ohtsubo; S Mitsuyama; Saho Ohno-Nakamura; Nobuyoshi Shimizu; Shinsei Minoshima
KMeyeDB: a graphical database of mutations in genes that cause eye diseases.
Human mutation 2010;31(6):667-74.
2010: Joon Young Park; Yasuhiro Takagi; Miyuki Yamatani; Kohsuke Honda; Shuichi Asakawa; Nobuyoshi Shimizu; Takeshi Omasa; Hisao Ohtake
Identification and analysis of specific chromosomal region adjacent to exogenous Dhfr-amplified region in Chinese hamster ovary cell genome.
Journal of bioscience and bioengineering 2010;109(5):504-11.
2010: Sachiko Tsuda; Tadao Kitagawa; Shigeo Takashima; Shuichi Asakawa; Nobuyoshi Shimizu; Hiroshi Mitani; Akihiro Shima; Makiko Tsutsumi; Hiroshi Hori; Kiyoshi Naruse; Yuji Ishikawa; Hiroyuki Takeda
FAK-mediated extracellular signals are essential for interkinetic nuclear migration and planar divisions in the neuroepithelium.
Journal of cell science 2010;123(Pt 3):484-96.
2010: Takashi Koyama; Shuichi Asakawa; Takayuki Katagiri; Atsushi Shimizu; Fernand F Fagutao; Rapeepat Mavichak; Mudjekeewis D Santos; Kanako Fuji; Takashi Sakamoto; Toshihide Kitakado; Hidehiro Kondo; Nobuyoshi Shimizu; Takashi Aoki; Ikuo Hirono
Hyper-expansion of large DNA segments in the genome of kuruma shrimp, Marsupenaeus japonicus.
BMC genomics 2010;11():141.
2009: Takeshi Omasa; Yihua Cao; Joon Young Park; Yasuhiro Takagi; Shuichi Kimura; Hidenori Yano; Kohsuke Honda; Shuichi Asakawa; Nobuyoshi Shimizu; Hisao Ohtake
Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells.
Biotechnology and bioengineering 2009;104(5):986-94.
2009: Shuichi Asakawa; Nobutaka Hattori; Atsushi Shimizu; Yoshiko Shimizu; Shinsei Minoshima; Yoshikuni Mizuno; Nobuyoshi Shimizu
Analysis of eighteen deletion breakpoints in the parkin gene.
Biochemical and biophysical research communications 2009;389(1):181-6.
2009: Norimasa Iwanami; Minoru Okada; Vu Q Hoa; Yasuhito Seo; Hiroshi Mitani; Takashi Sasaki; Nobuyoshi Shimizu; Hisato Kondoh; Makoto Furutani-Seiki; Yousuke Takahama
Ethylnitrosourea-induced thymus-defective mutants identify roles of KIAA1440, TRRAP, and SKIV2L2 in teleost organ development.
European journal of immunology 2009;39(9):2606-16.
2009: Masahiro Saito; Eisaku Nishida; Takashi Sasaki; Toshiyuki Yoneda; Nobuyoshi Shimizu
The KK-Periome database for transcripts of periodontal ligament development.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2009;312B(5):495-502.
2009: Padraic G Fallon; Takashi Sasaki; Aileen Sandilands; Linda E Campbell; Sean P Saunders; Niamh E Mangan; John J Callanan; Hiroshi Kawasaki; Aiko Shiohama; Akiharu Kubo; John P Sundberg; Richard B Presland; Philip Fleckman; Nobuyoshi Shimizu; Jun Kudoh; Alan D Irvine; Masayuki Amagai; W H Irwin McLean
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming.
Nature genetics 2009;41(5):602-8.
2009: Satoshi Maruyama; Jun Cheng; Susumu Shingaki; Takashi Tamura; Shuichi Asakawa; Shinsei Minoshima; Yoshiko Shimizu; Nobuyoshi Shimizu; Takashi Saku
Establishment and characterization of pleomorphic adenoma cell systems: an in-vitro demonstration of carcinomas arising secondarily from adenomas in the salivary gland.
BMC cancer 2009;9():247.
2009: Hisashi Hashimoto; Rieko Miyamoto; Naoki Watanabe; Dai Shiba; Kenjiro Ozato; Chikako Inoue; Yuko Kubo; Akihiko Koga; Tomoko Jindo; Takanori Narita; Kiyoshi Naruse; Kazuko Ohishi; Keiko Nogata; Tadasu Shin-i; Shuichi Asakawa; Nobuyoshi Shimizu; Tomotsune Miyamoto; Toshio Mochizuki; Takahiko Yokoyama; Hiroshi Hori; Hiroyuki Takeda; Yuji Kohara; Yuko Wakamatsu
Polycystic kidney disease in the medaka (Oryzias latipes) pc mutant caused by a mutation in the Gli-Similar3 (glis3) gene.
PloS one 2009;4(7):e6299.
2009: Nobuyoshi Shimizu
Extrachromosomal double minutes and chromosomal homogeneously staining regions as probes for chromosome research.
Cytogenetic and genome research 2009;124(3-4):312-26.
2008: Norimasa Iwanami; Tomokazu Higuchi; Yumi Sasano; Toshinobu Fujiwara; Vu Q Hoa; Minoru Okada; Sadiqur R Talukder; Sanae Kunimatsu; Jie Li; Fumi Saito; Chitralekha Bhattacharya; Angabin Matin; Takashi Sasaki; Nobuyoshi Shimizu; Hiroshi Mitani; Heinz Himmelbauer; Akihiro Momoi; Hisato Kondoh; Makoto Furutani-Seiki; Yousuke Takahama
WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ development.
PLoS genetics 2008;4(8):e1000171.
2008: Takashi Sasaki; Jun Kudoh; Tamotsu Ebihara; Aiko Shiohama; Shuichi Asakawa; Atsushi Shimizu; Atsushi Takayanagi; Itaru Dekio; Chieko Sadahira; Masayuki Amagai; Nobuyoshi Shimizu
Sequence analysis of filaggrin gene by novel shotgun method in Japanese atopic dermatitis.
Journal of dermatological science 2008;51(2):113-20.
2008: Marco T Páez; Toshiyuki Yamamoto; Ken-ichi Hayashi; Toshiyuki Yasuda; Naoki Harada; Naomichi Matsumoto; Kenji Kurosawa; Yoshiyuki Furutani; Shuichi Asakawa; Nobuyoshi Shimizu; Rumiko Matsuoka
Two patients with atypical interstitial deletions of 8p23.1: mapping of phenotypical traits.
American journal of medical genetics. Part A 2008;146A(9):1158-65.
2008: Chun-Shi Liang; Daisuke Ikeda; Shigeharu Kinoshita; Atsushi Shimizu; Takashi Sasaki; Shuichi Asakawa; Nobuyoshi Shimizu; Shugo Watabe
Myocyte enhancer factor 2 regulates expression of medaka Oryzias latipes fast skeletal myosin heavy chain genes in a temperature-dependent manner.
Gene 2008;407(1-2):42-53.
2008: Satoko Asai; Akiko Yamaki; Jun Kudoh; Nobuyoshi Shimizu; Yoshiko Shimizu
Analysis of the promoter region of human placenta-specific DSCR4 gene.
Biochimica et biophysica acta 2008;1779(1):40-50.
2007: Aiko Shiohama; Takashi Sasaki; Setsuko Noda; Shinsei Minoshima; Nobuyoshi Shimizu
Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.
Experimental cell research 2007;313(20):4196-207.
2007: Meng K Lim; Takeshi Kawamura; Yosuke Ohsawa; Masafumi Ohtsubo; Shuichi Asakawa; Atsushi Takayanagi; Nobuyoshi Shimizu
Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination.
Experimental cell research 2007;313(13):2858-74.
2007: Hao Yang; Takashi Sasaki; Shinsei Minoshima; Nobuyoshi Shimizu
Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.
Genomics 2007;90(2):249-60.
2007: Takashi Sasaki; Nobuyoshi Shimizu
Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins.
Gene 2007;396(2):312-20.
2007: Feng Su; Yumi Osada; Marc Ekker; Mario Chevrette; Atsushi Shimizu; Shuichi Asakawa; Aiko Shiohama; Takashi Sasaki; Nobuyoshi Shimizu; Toshiyuki Yamanaka; Takao Sasado; Hiroshi Mitani; Robert Geisler; Hisato Kondoh; Makoto Furutani-Seiki
Radiation hybrid maps of Medaka chromosomes LG 12, 17, and 22.
DNA research : an international journal for rapid publication of reports on genes and genomes 2007;14(3):135-40.
2007: Chikako Morinaga; Daisuke Saito; Shuhei Nakamura; Takashi Sasaki; Shuichi Asakawa; Nobuyoshi Shimizu; Hiroshi Mitani; Makoto Furutani-Seiki; Minoru Tanaka; Hisato Kondoh
The hotei mutation of medaka in the anti-Mullerian hormone receptor causes the dysregulation of germ cell and sexual development.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9691-6.
2007: Chun-Shi Liang; Atsushi Kobiyama; Atsushi Shimizu; Takashi Sasaki; Shuichi Asakawa; Nobuyoshi Shimizu; Shugo Watabe
Fast skeletal muscle myosin heavy chain gene cluster of medaka Oryzias latipes enrolled in temperature adaptation.
Physiological genomics 2007;29(2):201-14.
2007: Shuichiro Imai; Takashi Sasaki; Atsushi Shimizu; Shuichi Asakawa; Hiroshi Hori; Nobuyoshi Shimizu
The genome size evolution of medaka (Oryzias latipes) and fugu (Takifugu rubripes).
Genes & genetic systems 2007;82(2):135-44.
2007: Mari Maegawa; Kenji Takeuchi; Eishi Funakoshi; Katsumi Kawasaki; Kazuto Nishio; Nobuyoshi Shimizu; Fumiaki Ito
Growth stimulation of non-small cell lung cancer cell lines by antibody against epidermal growth factor receptor promoting formation of ErbB2/ErbB3 heterodimers.
Molecular cancer research : MCR 2007;5(4):393-401.
2007: Hayato Yokoi; Atsuko Shimada; Matthias Carl; Shigeo Takashima; Daisuke Kobayashi; Takanori Narita; Tomoko Jindo; Tetsuaki Kimura; Tadao Kitagawa; Takahiro Kage; Atsushi Sawada; Kiyoshi Naruse; Shuichi Asakawa; Nobuyoshi Shimizu; Hiroshi Mitani; Akihiro Shima; Makiko Tsutsumi; Hiroshi Hori; Joachim Wittbrodt; Yumiko Saga; Yuji Ishikawa; Kazuo Araki; Hiroyuki Takeda
Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships.
Developmental biology 2007;304(1):326-37.
2007: Mikio Kato; Takeshi Haku; Takeshi Hibino; Harumi Fukada; Yumiko Mishima; Ichiro Yamashita; Shinsei Minoshima; Kuniaki Nagayama; Nobuyoshi Shimizu
Stable minihairpin structures forming at minisatellite DNA isolated from yellow fin sea bream Acanthopagrus latus.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2007;146(3):427-37.
2007: Nobuyoshi Shimizu; Masafumi Ohtsubo; Shinsei Minoshima
MutationView/KMcancerDB: a database for cancer gene mutations.
Cancer science 2007;98(3):259-67.
2007: Toshiaki Shinojima; Mototsugu Oya; Atsushi Takayanagi; Ryuichi Mizuno; Nobuyoshi Shimizu; Masaru Murai
Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha.
Carcinogenesis 2007;28(3):529-36.
2007: Mikio Kato; Takeshi Haku; Takeshi Yamauchi; Shigeru Sugiyama; Kuniaki Nagayama; Nobuyoshi Shimizu
Structural characterization of supercoiled DNA containing a minisatellite repeat that has polypurine/polypyrimidine stretch.
Nucleic acids symposium series (2004) 2007;(51):341-2.
2007: Toshio Kawano; Chunxia Wang; Yoshihiro Hotta; Miho Sato; Emi Iwata-Amano; Akiko Hikoya; Naoya Fujita; Norihisa Koyama; Shoichiro Shirai; Noriyuki Azuma; Masafumi Ohtsubo; Nobuyoshi Shimizu; Shinsei Minoshima
Three novel mutations of the PAX6 gene in Japanese aniridia patients.
Journal of human genetics 2007;52(7):571-4.
2007: Takashi Sasaki; Atsushi Shimizu; Sabine K Ishikawa; Shuichiro Imai; Shuichi Asakawa; Yuji Murayama; Maryam Zadeh Khorasani; Hiroshi Mitani; Makoto Furutani-Seiki; Hisato Kondoh; Indrajit Nanda; Michael Schmid; Manfred Schartl; Masaru Nonaka; Hiroyuki Takeda; Hiroshi Hori; Heinz Himmelbauer; Akihiro Shima; Nobuyoshi Shimizu
The DNA sequence of medaka chromosome LG22.
Genomics 2007;89(1):124-33.
2006: Eishi Funakoshi; Masaki Fukui; Ayako Hamano; Hiroshi Okamoto; Chie Sugiyama; Norito Nishiyama; Kiyokazu Ogita; Takamitsu Hori; Nobuyoshi Shimizu; Fumiaki Ito
Expression of m-Golsyn/Syntabulin gene during mouse brain development.
Neuroscience letters 2006;403(3):244-9.
2006: Mariko Kondo; Ute Hornung; Indrajit Nanda; Shuichiro Imai; Takashi Sasaki; Atsushi Shimizu; Shuichi Asakawa; Hiroshi Hori; Michael Schmid; Nobuyoshi Shimizu; Manfred Schartl
Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka.
Genome research 2006;16(7):815-26.
2006: Gene Kurosawa; Naofumi Takamatsu; Masayoshi Takahashi; Mariko Sumitomo; Emi Sanaka; Kouji Yamada; Kazuhiro Nishii; Masaru Matsuda; Shuichi Asakawa; Hiroshi Ishiguro; Keiji Miura; Yoshikazu Kurosawa; Nobuyoshi Shimizu; Yuji Kohara; Hiroshi Hori
Organization and structure of hox gene loci in medaka genome and comparison with those of pufferfish and zebrafish genomes.
Gene 2006;370():75-82.
2006: Nobuyoshi Shimizu; Takashi Sasaki; Shuichi Asakawa; Atsushi Shimizu; Sabine K Ishikawa; Shuichiro Imai; Yuji Murayama; Heinz Himmelbauer; Hiroshi Mitani; Makoto Furutani-Seiki; Hisato Kondoh; Manfred Schartl; Masaru Nonaka; Hiroyuki Takeda; Hiroshi Hori; Akihiro Shima
Comparative genomics of medaka and fugu.
Comparative biochemistry and physiology. Part D, Genomics & proteomics 2006;1(1):6-12.
2006: Hiroshi Mitani; Y Kamei; Shoji Fukamachi; Shoji Oda; T Sasaki; Shuichi Asakawa; Takeshi Todo; Nobuyoshi Shimizu
The medaka genome: why we need multiple fish models in vertebrate functional genomics.
Genome dynamics 2006;2():165-82.
2006: Eishi Funakoshi; Ayako Hamano; Masaki Fukui; Norito Nishiyama; Kiyokazu Ogita; Nobuyoshi Shimizu; Fumiaki Ito
Molecular cloning of the m-Golsyn gene and its expression in the mouse brain.
Gene expression 2006;13(1):27-40.
2005: Michiyo Okui; Akiko Yamaki; Atsushi Takayanagi; Jun Kudoh; Nobuyoshi Shimizu; Yoshiko Shimizu
Transcription factor single-minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases.
Experimental cell research 2005;309(1):220-8.
2005: Osamu Takase; Takeshi Marumo; Naohiko Imai; Junichi Hirahashi; Atsushi Takayanagi; Keiichi Hishikawa; Matsuhiko Hayashi; Nobuyoshi Shimizu; Toshiro Fujita; Takao Saruta
NF-kappaB-dependent increase in intrarenal angiotensin II induced by proteinuria.
Kidney international 2005;68(2):464-73.
2005: Thorsten Henrich; Mirana Ramialison; Beate Wittbrodt; Beatrice Assouline; Franck Bourrat; Anja Berger; Heinz Himmelbauer; Takashi Sasaki; Nobuyoshi Shimizu; Monte Westerfield; Hisato Kondoh; Joachim Wittbrodt
MEPD: a resource for medaka gene expression patterns.
Bioinformatics (Oxford, England) 2005;21(14):3195-7.
2005: Kentaro Tsukamoto; Shinpei Hayashi; Megumi Y Matsuo; Masaru Nonaka; Mariko Kondo; Akihiro Shima; Shuichi Asakawa; Nobuyoshi Shimizu; Masaru Nonaka
Unprecedented intraspecific diversity of the MHC class I region of a teleost medaka, Oryzias latipes.
Immunogenetics 2005;57(6):420-31.
2005: Kazunori Shibuya; Jun Kudoh; Michiyo Okui; Nobuyoshi Shimizu
Identification of a novel zinc finger protein gene (ZNF298) in the GAP2 of human chromosome 21q.
Biochemical and biophysical research communications 2005;332(2):557-68.
2005: Yutaka Machida; Tomoki Chiba; Atsushi Takayanagi; Yoshikazu Tanaka; Masato Asanuma; Norio Ogawa; Akihiko Koyama; Takeshi Iwatsubo; Shosuke Ito; Poul Hening Jansen; Nobuyoshi Shimizu; Keiji Tanaka; Yoshikuni Mizuno; Nobutaka Hattori
Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells.
Biochemical and biophysical research communications 2005;332(1):233-40.
2005: Gamal E Elmesiry; Sayaka Okai; Shingo Hokabe; Shinsei Minoshima; Shigeru Sugiyama; Tomoyuki Yoshino; Toshio Ohtani; Nobuyoshi Shimizu; Mikio Kato
Isolation and characterization of simple repeat sequences from the yellow fin sea bream Acanthopagrus latus (Sparidae).
Molecular biology reports 2005;32(2):117-26.
2005: Makiko Nakaniwa; Makoto Hirayama; Atsushi Shimizu; Takashi Sasaki; Shuichi Asakawa; Nobuyoshi Shimizu; Shugo Watabe
Genomic sequences encoding two types of medaka hemopexin-like protein Wap65, and their gene expression profiles in embryos.
The Journal of experimental biology 2005;208(Pt 10):1915-25.
2005: Takuji Uemura; Jun Kudoh; Setsuko Noda; Shigenobu Kanba; Nobuyoshi Shimizu
Characterization of human and mouse TRPM2 genes: identification of a novel N-terminal truncated protein specifically expressed in human striatum.
Biochemical and biophysical research communications 2005;328(4):1232-43.
2005: Jun Wang; Jun Kudoh; Atsushi Takayanagi; Nobuyoshi Shimizu
Novel human BTB/POZ domain-containing zinc finger protein ZNF295 is directly associated with ZFP161.
Biochemical and biophysical research communications 2005;327(2):615-27.
2005: Eishi Funakoshi; Kin-Ya Nakagawa; Ayako Hamano; Takamitsu Hori; Atsushi Shimizu; Shuichi Asakawa; Nobuyoshi Shimizu; Fumiaki Ito
Molecular cloning and characterization of gene for Golgi-localized syntaphilin-related protein on human chromosome 8q23.
Gene 2005;344():259-71.
2004: Tomoyo Funayama; Karin Ishikawa; Yuichiro Ohtake; Tomihiko Tanino; Daijiro Kurosaka; Itaru Kimura; Kotaro Suzuki; Hidenao Ideta; Kenji Nakamoto; Noriko Yasuda; Takuro Fujimaki; Akira Murakami; Ryo Asaoka; Yoshihiro Hotta; Hidenobu Tanihara; Takashi Kanamoto; Hiromu Mishima; Takeo Fukuchi; Haruki Abe; Takeshi Iwata; Naoki Shimada; Jun Kudoh; Nobuyoshi Shimizu; Yukihiko Mashima
Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma.
Investigative ophthalmology & visual science 2004;45(12):4359-67.
2004: Shoji Fukamachi; Shuichi Asakawa; Yuko Wakamatsu; Nobuyoshi Shimizu; Hiroshi Mitani; Akihiro Shima
Conserved function of medaka pink-eyed dilution in melanin synthesis and its divergent transcriptional regulation in gonads among vertebrates.
Genetics 2004;168(3):1519-27.
2004: Motoki N Tada; Kouji Senzaki; Yuumi Tai; Hirofumi Morishita; Yusuke Z Tanaka; Yoji Murata; Yasuyuki Ishii; Shuichi Asakawa; Nobuyoshi Shimizu; Hidehiko Sugino; Takeshi Yagi
Genomic organization and transcripts of the zebrafish Protocadherin genes.
Gene 2004;340(2):197-211.
2004: Katsuhiro Hosono; Takashi Sasaki; Shinsei Minoshima; Nobuyoshi Shimizu
Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.
Gene 2004;340(1):31-43.
2004: Yasuko Hatano; Yuanzhe Li; Kenichi Sato; Shuichi Asakawa; Yasuhiro Yamamura; Hiroyuki Tomiyama; Hiroyo Yoshino; Masato Asahina; Susumu Kobayashi; Sharon Hassin-Baer; Chin-Song Lu; Arlene R Ng; Raymond L Rosales; Nobuyoshi Shimizu; Tatsushi Toda; Yoshikuni Mizuno; Nobutaka Hattori
Novel PINK1 mutations in early-onset parkinsonism.
Annals of neurology 2004;56(3):424-7.
2004: Hiroko Akiyoshi; Shigetsugu Hatakeyama; Jukka Pitkänen; Yasuhiro Mouri; Vassilis Doucas; Jun Kudoh; Kyoko Tsurugaya; Daisuke Uchida; Akemi Matsushima; Kiyotaka Oshikawa; Keiichi I Nakayama; Nobuyoshi Shimizu; Pärt Peterson; Mitsuru Matsumoto
Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner.
The Journal of biological chemistry 2004;279(32):33984-91.
2004: Kazunori Shibuya; Kentaro Nagamine; Michiyo Okui; Yosuke Ohsawa; Shuichi Asakawa; Shinsei Minoshima; Tetsu Hase; Jun Kudoh; Nobuyoshi Shimizu
Initial characterization of an uromodulin-like 1 gene on human chromosome 21q22.3.
Biochemical and biophysical research communications 2004;319(4):1181-9.
2004: Masamichi Saga; Yukihiko Mashima; Jun Kudoh; Yoshihisa Oguchi; Nobuyoshi Shimizu
Gene analysis and evaluation of the single founder effect in Japanese patients with Oguchi disease.
Japanese journal of ophthalmology 2004;48(4):350-2.
2004: Maryam Zadeh Khorasani; Steffen Hennig; Gabriele Imre; Shuichi Asakawa; Stefanie Palczewski; Anja Berger; Hiroshi Hori; Kiyoshi Naruse; Hiroshi Mitani; Akihiro Shima; Hans Lehrach; Joachim Wittbrodt; Hisato Kondoh; Nobuyoshi Shimizu; Heinz Himmelbauer
A first generation physical map of the medaka genome in BACs essential for positional cloning and clone-by-clone based genomic sequencing.
Mechanisms of development 2004;121(7-8):903-13.
2004: Kiyoshi Naruse; Hiroshi Hori; Nobuyoshi Shimizu; Yuji Kohara; Hiroyuki Takeda
Medaka genomics: a bridge between mutant phenotype and gene function.
Mechanisms of development 2004;121(7-8):619-28.
2004: Shoichi Yahagi; Kazunori Shibuya; Izumi Obayashi; Hitoshi Masaki; Yoshiko Kurata; Jun Kudoh; Nobuyoshi Shimizu
Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11.
Biochemical and biophysical research communications 2004;318(3):655-64.
2004: Masataka Suzuki; Atsushi Takayanagi; Nobuyoshi Shimizu
Targeted gene delivery using humanized single-chain antibody with negatively charged oligopeptide tail.
Cancer science 2004;95(5):424-9.
2004: Shinichiro Maruyama; Osami Misumi; Yasuyuki Ishii; Shuichi Asakawa; Atsushi Shimizu; Takashi Sasaki; Motomichi Matsuzaki; Tadasu Shin-i; Hisayoshi Nozaki; Yuji Kohara; Nobuyoshi Shimizu; Tsuneyoshi Kuroiwa
The minimal eukaryotic ribosomal DNA units in the primitive red alga Cyanidioschyzon merolae.
DNA research : an international journal for rapid publication of reports on genes and genomes 2004;11(2):83-91.
2004: Takuya Toramoto; Daisuke Ikeda; Yoshihiro Ochiai; Shinsei Minoshima; Nobuyoshi Shimizu; Shugo Watabe
Multiple gene organization of pufferfish Fugu rubripes tropomyosin isoforms and tissue distribution of their transcripts.
Gene 2004;331():41-51.
2004: Hidehiko Sugino; Hiroshi Yanase; Shun Hamada; Ken Kurokawa; Shuichi Asakawa; Nobuyoshi Shimizu; Takeshi Yagi
Distinct genomic sequence of the CNR/Pcdhalpha genes in chicken.
Biochemical and biophysical research communications 2004;316(2):437-45.
2004: Kazunori Shibuya; Izumi Obayashi; Shuichi Asakawa; Shinsei Minoshima; Jun Kudoh; Nobuyoshi Shimizu
A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.
Genomics 2004;83(4):679-93.
2004: Yukihiko Mashima; Makoto Nagano; Tomoyo Funayama; Qiang Zhang; Tohru Egashira; Jun Kudho; Nobuyoshi Shimizu; Yoshihisa Oguchi
Rapid quantification of the heteroplasmy of mutant mitochondrial DNAs in Leber's hereditary optic neuropathy using the Invader technology.
Clinical biochemistry 2004;37(4):268-76.
2004: Kazunori Shibuya; Jun Kudoh; Izumi Obayashi; Atsushi Shimizu; Takashi Sasaki; Shinsei Minoshima; Nobuyoshi Shimizu
Comparative genomics of the keratin-associated protein (KAP) gene clusters in human, chimpanzee, and baboon.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(3):179-92.
2004: Masahiko Watabe; Keiichi Hishikawa; Atsushi Takayanagi; Nobuyoshi Shimizu; Toshio Nakaki
Caffeic acid phenethyl ester induces apoptosis by inhibition of NFkappaB and activation of Fas in human breast cancer MCF-7 cells.
The Journal of biological chemistry 2004;279(7):6017-26.
2004: Yasuyuki Ishii; Shuichi Asakawa; Yusuke Taguchi; Shoko Ishibashi; Takeshi Yagi; Nobuyoshi Shimizu
Construction of BAC library for the amphibian Xenopus tropicalis.
Genes & genetic systems 2004;79(1):49-51.
2004: Daisuke Uchida; Shigetsugu Hatakeyama; Akemi Matsushima; Hongwei Han; Satoshi Ishido; Hak Hotta; Jun Kudoh; Nobuyoshi Shimizu; Vassilis Doucas; Keiichi I Nakayama; Noriyuki Kuroda; Mitsuru Matsumoto
AIRE functions as an E3 ubiquitin ligase.
The Journal of experimental medicine 2004;199(2):167-72.
2004: Akiko Yamaki; Jun Kudoh; Nobuyoshi Shimizu; Yoshiko Shimizu
A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM2.
Biochemical and biophysical research communications 2004;313(3):482-8.
2004: Mikio Kato; Shingo Hokabe; Takeshi Haku; Shinsei Minoshima; Kuniaki Nagayama; Nobuyoshi Shimizu
Single-stranded DNA structure of a minisatellite sequence isolated from Acanthopagrus latus.
Nucleic acids symposium series (2004) 2004;(48):153-4.
2004: Manfred Schartl; Indrajit Nanda; Mariko Kondo; Michael Schmid; Shuichi Asakawa; Takashi Sasaki; Nobuyoshi Shimizu; Thorsten Henrich; Joachim Wittbrodt; Makoto Furutani-Seiki; Hisato Kondoh; Heinz Himmelbauer; Yunhan Hong; Akihiko Koga; Masaru Nonaka; Hiroshi Mitani; Akihiro Shima
Current status of medaka genetics and genomics. The Medaka Genome Initiative (MGI).
Methods in cell biology 2004;77():173-99.
2003: Hisato Yagi; Yoshiyuki Furutani; Hiromichi Hamada; Takashi Sasaki; Shuichi Asakawa; Shinsei Minoshima; Fukiko Ichida; Kunitaka Joo; Misa Kimura; Shinichiro Imamura; Naoyuki Kamatani; Kazuo Momma; Atsuyoshi Takao; Makoto Nakazawa; Nobuyoshi Shimizu; Rumiko Matsuoka
Role of TBX1 in human del22q11.2 syndrome.
Lancet 2003;362(9393):1366-73.
2003: Yuko Yao; Takehiro Yamamoto; Makiko Tsutsumi; Masaru Matsuda; Hiroshi Hori; Kiyoshi Naruse; Hiroshi Mitani; Akihiro Shima; Shuichi Asakawa; Nobuyoshi Shimizu; Norio Suzuki
Genomic structure and expression of the soluble guanylyl cyclase alpha2 subunit gene in the medaka fish Oryzias latipes.
Zoological science 2003;20(10):1293-304.
2003: Kataaki Okubo; Shingo Ishii; Jun Ishida; Hiroshi Mitani; Kiyoshi Naruse; Mariko Kondo; Akihiro Shima; Minoru Tanaka; Shuichi Asakawa; Nobuyoshi Shimizu; Katsumi Aida
A novel third gonadotropin-releasing hormone receptor in the medaka Oryzias latipes: evolutionary and functional implications.
Gene 2003;314():121-31.
2003: Atsushi Shimizu; Shuichi Asakawa; Takashi Sasaki; Satoru Yamazaki; Hidehisa Yamagata; Jun Kudoh; Shinsei Minoshima; Ikuko Kondo; Nobuyoshi Shimizu
A novel giant gene CSMD3 encoding a protein with CUB and sushi multiple domains: a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1.
Biochemical and biophysical research communications 2003;309(1):143-54.
2003: Eishi Funakoshi; Takamitsu Hori; Tokuko Haraguchi; Yasushi Hiraoka; Jun Kudoh; Nobuyoshi Shimizu; Fumiaki Ito
Overexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosome.
BMC cell biology 2003;4():12.
2003: Takashi Sasaki; Aiko Shiohama; Shinsei Minoshima; Nobuyoshi Shimizu
Identification of eight members of the Argonaute family in the human genome small star, filled.
Genomics 2003;82(3):323-30.
2003: Elizabeth Spiteri; Melanie Babcock; Catherine D Kashork; Keiko Wakui; Swarna Gogineni; Debbie A Lewis; Kisa M Williams; Shinsei Minoshima; Takashi Sasaki; Nobuyoshi Shimizu; Lorraine Potocki; Venkat Pulijaal; Alan L Shanske; Lisa Shaffer; Bernice E Morrow
Frequent translocations occur between low copy repeats on chromosome 22q11.2 (LCR22s) and telomeric bands of partner chromosomes.
Human molecular genetics 2003;12(15):1823-37.
2003: Mikio Kato; Shingo Hokabe; Shuji Itakura; Shinsei Minoshima; Yuri L Lyubchenko; Theodor D Gurkov; Hiroshi Okawara; Kuniaki Nagayama; Nobuyoshi Shimizu
Interarm interaction of DNA cruciform forming at a short inverted repeat sequence.
Biophysical journal 2003;85(1):402-8.
2003: Daisuke Ikeda; Takuya Toramoto; Yoshihiro Ochiai; Hiroaki Suetake; Yuzuru Suzuki; Shinsei Minoshima; Nobuyoshi Shimizu; Shugo Watabe
Identification of novel tropomyosin 1 genes of pufferfish (Fugu rubripes) on genomic sequences and tissue distribution of their transcripts.
Molecular biology reports 2003;30(2):83-90.
2003: Kenshi Yamasaki; Nobuko Toriu; Yasushi Hanakawa; Yuji Shirakata; Koji Sayama; Atsushi Takayanagi; Masafumi Ohtsubo; Shinobu Gamou; Nobuyoshi Shimizu; Makiko Fujii; Kohei Miyazono; Koji Hashimoto
Keratinocyte growth inhibition by high-dose epidermal growth factor is mediated by transforming growth factor beta autoinduction: a negative feedback mechanism for keratinocyte growth.
The Journal of investigative dermatology 2003;120(6):1030-7.
2003: Masafumi Ohtsubo; Kazunori Shibuya; Jun Kudoh; Shinsei Minoshima; Nobuyoshi Shimizu
[Integrated database for mutations in disease genes: MutationView/KMDB].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2003;48(6):762-9.
2003: M Suzuki; Atsushi Takayanagi; Nobuyoshi Shimizu
Recombinant single-chain antibodies with various oligopeptide tails for targeted gene delivery.
Gene therapy 2003;10(9):781-8.
2003: Aiko Shiohama; Takashi Sasaki; Setsuko Noda; Shinsei Minoshima; Nobuyoshi Shimizu
Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region.
Biochemical and biophysical research communications 2003;304(1):184-90.
2003: Masafumi Ohtsubo; Nobuyoshi Shimizu; Shinsei Minoshima
[The integrated database for mutations in disease-causing genes: Mutation View/KMDB].
Seikagaku. The Journal of Japanese Biochemical Society 2003;75(4):311-8.
2003: Mariko Kondo; Indrajit Nanda; Ute Hornung; Shuichi Asakawa; Nobuyoshi Shimizu; Hiroshi Mitani; Michael Schmid; Akihiro Shima; Manfred Schartl
Absence of the candidate male sex-determining gene dmrt1b(Y) of medaka from other fish species.
Current biology : CB 2003;13(5):416-20.
2003: Mototsugu Oya; Atsushi Takayanagi; Akio Horiguchi; Ryuichi Mizuno; Masafumi Ohtsubo; Ken Marumo; Nobuyoshi Shimizu; Masaru Murai
Increased nuclear factor-kappa B activation is related to the tumor development of renal cell carcinoma.
Carcinogenesis 2003;24(3):377-84.
2003: Osamu Takase; Junichi Hirahashi; Atsushi Takayanagi; Akihiro Chikaraishi; Takeshi Marumo; Yuri Ozawa; Matsuhiko Hayashi; Nobuyoshi Shimizu; Takao Saruta
Gene transfer of truncated IkappaBalpha prevents tubulointerstitial injury.
Kidney international 2003;63(2):501-13.
2002: Hirohisa Harada; Go Wakabayashi; Atsushi Takayanagi; Motohide Shimazu; Kenji Matsumoto; Hideaki Obara; Nobuyoshi Shimizu; Masaki Kitajima
Transfer of the interleukin-1 receptor antagonist gene into rat liver abrogates hepatic ischemia-reperfusion injury.
Transplantation 2002;74(10):1434-41.
2002: Michel Guipponi; Grégoire Vuagniaux; Marie Wattenhofer; Kazunori Shibuya; Maria Vazquez; Loretta Dougherty; Nathalie Scamuffa; Elizabeth Guida; Michiyo Okui; Colette Rossier; Manuela Hancock; Karine Buchet; Alexandre Reymond; Edith Hummler; Phillip L Marzella; Jun Kudoh; Nobuyoshi Shimizu; Hamish Scott; Stylianos E Antonarakis; Bernard C Rossier
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro.
Human molecular genetics 2002;11(23):2829-36.
2002: Indrajit Nanda; Mariko Kondo; Ute Hornung; Shuichi Asakawa; Christoph Winkler; Atsushi Shimizu; Zhihong Shan; Thomas Haaf; Nobuyoshi Shimizu; Akihiro Shima; Michael Schmid; Manfred Schartl
A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11778-83.
2002: Alexander Froschauer; Cornelia Körting; Takayuki Katagiri; Takashi Aoki; Shuichi Asakawa; Nobuyoshi Shimizu; Manfred Schartl; Jean-Nicolas Volff
Construction and initial analysis of bacterial artificial chromosome (BAC) contigs from the sex-determining region of the platyfish Xiphophorus maculatus.
Gene 2002;295(2):247-54.
2002: Mariko Kondo; Alexander Froschauer; Akiko Kitano; Indrajit Nanda; Ute Hornung; Jean-Nicolas Volff; Shuichi Asakawa; Hiroshi Mitani; Kiyoshi Naruse; Minoru Tanaka; Michael Schmid; Nobuyoshi Shimizu; Manfred Schartl; Akihiro Shima
Molecular cloning and characterization of DMRT genes from the medaka Oryzias latipes and the platyfish Xiphophorus maculatus.
Gene 2002;295(2):213-22.
2002: Mikio Kato; Chad J McAllister; Shingo Hokabe; Nobuyoshi Shimizu; Yuri L Lyubchenko
Structural heterogeneity of pyrimidine/purine-biased DNA sequence analyzed by atomic force microscopy.
European journal of biochemistry / FEBS 2002;269(15):3632-6.
2002: Kataaki Okubo; Hiroshi Mitani; Kiyoshi Naruse; Mariko Kondo; Akihiro Shima; Minoru Tanaka; Shuichi Asakawa; Nobuyoshi Shimizu; Yasutoshi Yoshiura; Katsumi Aida
Structural characterization of GnRH loci in the medaka genome.
Gene 2002;293(1-2):181-9.
2002: Maki Yoshihama; Tamayo Uechi; Shuichi Asakawa; Kazuhiko Kawasaki; Seishi Kato; Sayomi Higa; Noriko Maeda; Shinsei Minoshima; Tatsuo Tanaka; Nobuyoshi Shimizu; Naoya Kenmochi
The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.
Genome research 2002;12(3):379-90.
2002: Megumi Y Matsuo; Shuichi Asakawa; Nobuyoshi Shimizu; Hiroshi Kimura; Masaru Nonaka
Nucleotide sequence of the MHC class I genomic region of a teleost, the medaka (Oryzias latipes).
Immunogenetics 2002;53(10-11):930-40.
2002: Shingo Hokabe; Theodor D Gurkov; Hiroshi Okawara; Kuniaki Nagayama; Shinsei Minoshima; Nobuyoshi Shimizu; Mikio Kato
Chemical probing and electron microscopic analysis of alternative DNA structure formed in an inverted repeat sequence.
Nucleic acids research. Supplement (2001) 2002;(2):217-8.
2002: Nobuyoshi Shimizu
[Drug discovery based on the human genome sciences].
Gan to kagaku ryoho. Cancer & chemotherapy 2002;29(1):1-6.
2001: Takashi Sasaki; Shinsei Minoshima; Aiko Shiohama; A Shintani; Atsushi Shimizu; Shuichi Asakawa; K Kawasaki; Nobuyoshi Shimizu
Molecular cloning of a member of the facilitative glucose transporter gene family GLUT11 (SLC2A11) and identification of transcription variants.
Biochemical and biophysical research communications 2001;289(5):1218-24.
2001: Shuichi Asakawa; Atsushi Takayanagi; Takashi Sasaki; Atsushi Shimizu; A Shintani; K Kawasaki; Andrew Mungall; S Beck; Shinsei Minoshima; Nobuyoshi Shimizu
The genomic structure and promoter region of the human parkin gene.
Biochemical and biophysical research communications 2001;286(5):863-8.
2001: M Heino; Pärt Peterson; Jun Kudoh; Nobuyoshi Shimizu; Stylianos E Antonarakis; Hamish Scott; Kai Krohn
APECED mutations in the autoimmune regulator (AIRE) gene.
Human mutation 2001;18(3):205-11.
2001: Nobuyoshi Shimizu; T Ochi; K Itonaga
Replication timing of amplified genetic regions relates to intranuclear localization but not to genetic activity or G/R band.
Experimental cell research 2001;268(2):201-10.
2001: S Kondo; Yoshikazu Kuwahara; Mariko Kondo; Kiyoshi Naruse; Hiroshi Mitani; Yuko Wakamatsu; Kenjiro Ozato; Shuichi Asakawa; Nobuyoshi Shimizu; Akihiro Shima
The medaka rs-3 locus required for scale development encodes ectodysplasin-A receptor.
Current biology : CB 2001;11(15):1202-6.
2001: S i Kubo; Toshiaki Kitami; S Noda; Hideki Shimura; Yasuo Uchiyama; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno; Nobutaka Hattori
Parkin is associated with cellular vesicles.
Journal of neurochemistry 2001;78(1):42-54.
2001: Mototsugu Oya; Masafumi Ohtsubo; Atsushi Takayanagi; M Tachibana; Nobuyoshi Shimizu; Masaru Murai
Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells.
Oncogene 2001;20(29):3888-96.
2001: M Wang; T Suzuki; Tohru Kitada; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; Keiji Tanaka; Yoshikuni Mizuno; Nobutaka Hattori
Developmental changes in the expression of parkin and UbcR7, a parkin-interacting and ubiquitin-conjugating enzyme, in rat brain.
Journal of neurochemistry 2001;77(6):1561-8.
2001: Akiko Yamaki; J Tochigi; Jun Kudoh; S Minoshima; Nobuyoshi Shimizu; Yoshiko Shimizu
Molecular mechanisms of human single-minded 2 (SIM2) gene expression: identification of a promoter site in the SIM2 genomic sequence.
Gene 2001;270(1-2):265-75.
2001: K Kawasaki; Shinsei Minoshima; E Nakato; K Shibuya; A Shintani; Shuichi Asakawa; Takashi Sasaki; H Gustav Klobeck; Gabriele Combriato; H G Zachau; Nobuyoshi Shimizu
Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes.
European journal of immunology 2001;31(4):1017-28.
2001: K Obata; T Fukuda; R Morishita; Shunnosuke Abe; S Asakawa; S Yamaguchi; M Yoshino; K Ihara; K Murayama; Kazuhiro Shigemoto; Nobuyoshi Shimizu; Ikuko Kondo
Human biotin-containing subunit of 3-methylcrotonyl-CoA carboxylase gene (MCCA): cDNA sequence, genomic organization, localization to chromosomal band 3q27, and expression.
Genomics 2001;72(2):145-52.
2001: Marie Wattenhofer; Kazunori Shibuya; Jun Kudoh; Robert Lyle; Joäelle Michaud; Colette Rossier; K Kawasaki; Shuichi Asakawa; Shinsei Minoshima; A Berry; Batsheva Bonne-Tamir; Nobuyoshi Shimizu; Stylianos E Antonarakis; Hamish Scott
Isolation and characterization of the UBASH3A gene on 21q22.3 encoding a potential nuclear protein with a novel combination of domains.
Human genetics 2001;108(2):140-7.
2001: Mikio Kato; Theodor D Gurkov; Gamal E Elmesiry; Nobuyoshi Shimizu; Kuniaki Nagayama
Electron microscopic imaging of supercoiled DNA containing highly biased sequence.
Nucleic acids research. Supplement (2001) 2001;(1):157-8.
2001: T Takahashi; Y Kawamura; N Sakata; Gamal E Elmesiry; Y Takemon; Kazumi Tanida; Shinsei Minoshima; Nobuyoshi Shimizu; Mikio Kato
Nucleotide sequence of BamHI family satellite DNA and its unit length polymorphism in bluegill sunfish Lepomis macrochirus.
Molecular biology reports 2001;28(2):119-22.
2001: Yoshikuni Mizuno; Nobutaka Hattori; Tohru Kitada; Hiroto Matsumine; Hideo Mori; Hideki Shimura; S i Kubo; Hirokazu Kobayashi; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu
Familial Parkinson's disease. Alpha-synuclein and parkin.
Advances in neurology 2001;86():13-21.
2001: Shuji Yamashita; Atsushi Takayanagi; Nobuyoshi Shimizu
Effects of neonatal diethylstilbestrol exposure on c-fos and c-jun protooncogene expression in the mouse uterus.
Histology and histopathology 2001;16(1):131-40.
2001: Hamish Scott; Jun Kudoh; Marie Wattenhofer; Kazunori Shibuya; A Berry; R Chrast; Michel Guipponi; J Wang; K Kawasaki; Shuichi Asakawa; Shinsei Minoshima; F Younus; S Qasim Mehdi; Uppala Radhakrishna; MP Papasavvas; Corinne Gehrig; Colette Rossier; Michael Korostishevsky; A Gal; Nobuyoshi Shimizu; Batsheva Bonne-Tamir; Stylianos E Antonarakis
Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness.
Nature genetics 2001;27(1):59-63.
2001: Shinsei Minoshima; S Mitsuyama; Masafumi Ohtsubo; Takeshi Kawamura; S Ito; S Shibamoto; F Ito; Nobuyoshi Shimizu
The KMDB/MutationView: a mutation database for human disease genes.
Nucleic acids research 2001;29(1):327-8.
2000: Lucia Bartoloni; Marie Wattenhofer; Jun Kudoh; A Berry; Kazunori Shibuya; K Kawasaki; J Wang; Shuichi Asakawa; Ilana Talior; Batsheva Bonne-Tamir; Colette Rossier; Joäelle Michaud; Edward RB McCabe; Shinsei Minoshima; Nobuyoshi Shimizu; Hamish Scott; Stylianos E Antonarakis
Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency.
Genomics 2000;70(2):190-200.
2000: Nobuyoshi Shimizu
[Frontiers of the human genome project: complete sequencing of the chromosomes 22 and 21].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(14):2432-40.
2000: Hideaki Obara; Atsushi Takayanagi; Junichi Hirahashi; K Tanaka; Go Wakabayashi; K Matsumoto; Motohide Shimazu; Nobuyoshi Shimizu; M Kitajima
Overexpression of truncated IkappaBalpha induces TNF-alpha-dependent apoptosis in human vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(10):2198-204.
2000: Nobutaka Hattori; Hideki Shimura; S i Kubo; Tohru Kitada; M Wang; Shuichi Asakawa; S Minashima; Nobuyoshi Shimizu; T Suzuki; Keiji Tanaka; Yoshikuni Mizuno
Autosomal recessive juvenile parkinsonism: a key to understanding nigral degeneration in sporadic Parkinson's disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20 Suppl():S85-90.
2000: Yukihiko Mashima; Masamichi Saga; Yoshiki Hiida; Yutaka Imamura; Jun Kudoh; Nobuyoshi Shimizu
Novel mutation in RP2 gene in two brothers with X-linked retinitis pigmentosa and mtDNA mutation of leber hereditary optic neuropathy who showed marked differences in clinical severity.
American journal of ophthalmology 2000;130(3):357-9.
2000: Ryo Kubota; Yukihiko Mashima; Yuichiro Ohtake; Tomihiko Tanino; T Kimura; Yoshihiro Hotta; A Kanai; S Tokuoka; I Azuma; Hidenobu Tanihara; M Inatani; Y Inoue; Jun Kudoh; Yoshihisa Oguchi; Nobuyoshi Shimizu
Novel mutations in the myocilin gene in Japanese glaucoma patients.
Human mutation 2000;16(3):270.
2000: Joäelle Michaud; Jun Kudoh; A Berry; Batsheva Bonne-Tamir; Maria D Lalioti; Colette Rossier; Kazunori Shibuya; K Kawasaki; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; Stylianos E Antonarakis; Hamish Scott
Isolation and characterization of a human chromosome 21q22.3 gene (WDR4) and its mouse homologue that code for a WD-repeat protein.
Genomics 2000;68(1):71-9.
2000: Michel Guipponi; K Brunschwig; Z Chamoun; Hamish Scott; K Shibuya; Jun Kudoh; A L Delezoide; S El Samadi; Zoubida Chettouh; Colette Rossier; Nobuyoshi Shimizu; F Mueller; Jean-Maurice Delabar; Stylianos E Antonarakis
C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning.
Genomics 2000;68(1):30-40.
2000: A Berry; Hamish Scott; Jun Kudoh; Ilana Talior; Michael Korostishevsky; Marie Wattenhofer; Michel Guipponi; C Barras; Colette Rossier; Kazunori Shibuya; J Wang; K Kawasaki; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; Stylianos E Antonarakis; B Bonné-Tamir
Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region.
Genomics 2000;68(1):22-9.
2000: K Kawasaki; Shinsei Minoshima; Nobuyoshi Shimizu
Propagation and maintenance of the 119 human immunoglobulin Vlambda genes and pseudogenes during evolution.
The Journal of experimental zoology 2000;288(2):120-34.
2000: M Heino; Pärt Peterson; Niko Sillanpää; S Guérin; L Wu; G Anderson; Hamish Scott; Stylianos E Antonarakis; Jun Kudoh; Nobuyoshi Shimizu; E J Jenkinson; Philippe Naquet; KJ Krohn
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse.
European journal of immunology 2000;30(7):1884-93.
2000: Hideki Shimura; Nobutaka Hattori; S i Kubo; Yoshikuni Mizuno; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; K Iwai; Tomoki Chiba; Keiji Tanaka; T Suzuki
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase.
Nature genetics 2000;25(3):302-5.
2000: Masafumi Ohtsubo; Atsushi Takayanagi; Shinobu Gamou; Nobuyoshi Shimizu
Interruption of NFkappaB-STAT1 signaling mediates EGF-induced cell-cycle arrest.
Journal of cellular physiology 2000;184(1):131-7.
2000: Jukka Pitkänen; Vassilis Doucas; Thomas Sternsdorf; T Nakajima; S Aratani; Kirsten Jensen; Hans Will; Perttu Vähämurto; Juha Ollila; Mauno Vihinen; Hamish Scott; Stylianos E Antonarakis; Jun Kudoh; Nobuyoshi Shimizu; Kai Krohn; Pärt Peterson
The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein.
The Journal of biological chemistry 2000;275(22):16802-9.
2000: Nobuyoshi Shimizu; S Minoshima
[Computer databases on cancer-related genes].
Nihon rinsho. Japanese journal of clinical medicine 2000;58(6):1211-8.
2000: Tohru Kitada; Shuichi Asakawa; Shinsei Minoshima; Yoshikuni Mizuno; Nobuyoshi Shimizu
Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(6):417-21.
2000: Kazunori Shibuya; Jun Kudoh; Shinsei Minoshima; K Kawasaki; Shuichi Asakawa; Nobuyoshi Shimizu
Isolation of two novel genes, DSCR5 and DSCR6, from Down syndrome critical region on human chromosome 21q22.2.
Biochemical and biophysical research communications 2000;271(3):693-8.
2000: Ulla Aapola; K Kawasaki; Hamish Scott; Juha Ollila; Mauno Vihinen; M Heino; A Shintani; K Kawasaki; Shinsei Minoshima; Kai Krohn; Stylianos E Antonarakis; Nobuyoshi Shimizu; Jun Kudoh; Pärt Peterson
Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family.
Genomics 2000;65(3):293-8.
2000: Nobuyoshi Shimizu; T Shimura; T Tanaka
Selective elimination of acentric double minutes from cancer cells through the extrusion of micronuclei.
Mutation research 2000;448(1):81-90.
2000: Tohru Kitada; Shuichi Asakawa; Hiroto Matsumine; Nobutaka Hattori; Hideki Shimura; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno
Progress in the clinical and molecular genetics of familial parkinsonism.
Neurogenetics 2000;2(4):207-18.
2000: Junichi Hirahashi; Atsushi Takayanagi; Keiichi Hishikawa; Osamu Takase; Akihiro Chikaraishi; Matsuhiko Hayashi; Nobuyoshi Shimizu; Takao Saruta
Overexpression of truncated I kappa B alpha potentiates TNF-alpha-induced apoptosis in mesangial cells.
Kidney international 2000;57(3):959-68.
2000: C M Proby; Takayuki Ota; Harumi Suzuki; Shigeo Koyasu; Shinobu Gamou; Nobuyoshi Shimizu; James K Wahl; Margaret J Wheelock; Takeji Nishikawa; Masayuki Amagai
Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris.
The British journal of dermatology 2000;142(2):321-30.
2000: T Tanaka; Nobuyoshi Shimizu
Induced detachment of acentric chromatin from mitotic chromosomes leads to their cytoplasmic localization at G(1) and the micronucleation by lamin reorganization at S phase.
Journal of cell science 2000;113 ( Pt 4)():697-707.
2000: H Takahashi; S Noda; Yukihiko Mashima; Ryo Kubota; Yuichiro Ohtake; Tomihiko Tanino; Jun Kudoh; S Minoshima; Yoshihisa Oguchi; Nobuyoshi Shimizu
The myocilin (MYOC) gene expression in the human trabecular meshwork.
Current eye research 2000;20(2):81-4.
2000: Nobutaka Hattori; Hideki Shimura; S i Kubo; M Wang; Nobuyoshi Shimizu; Keiji Tanaka; Yoshikuni Mizuno
Importance of familial Parkinson's disease and parkinsonism to the understanding of nigral degeneration in sporadic Parkinson's disease.
Journal of neural transmission. Supplementum 2000;(60):101-16.
2000: Nobuyoshi Shimizu; Shuichi Asakawa; Shinsei Minoshima; Tohru Kitada; Nobutaka Hattori; Hiroto Matsumine; Masayuki Yokochi; Yasuhiro Yamamura; Yoshikuni Mizuno
PARKIN as a pathogenic gene for autosomal recessive juvenile parkinsonism.
Journal of neural transmission. Supplementum 2000;(58):19-30.
2000: Shinsei Minoshima; S Mitsuyama; S Ohno; Takeshi Kawamura; Nobuyoshi Shimizu
Eye disorder database "KMeyeDB".
Human mutation 2000;15(1):95-8.
2000: Shinsei Minoshima; S Mitsuyama; S Ohno; Takeshi Kawamura; Nobuyoshi Shimizu
Keio Mutation Database (KMDB) for human disease gene mutations.
Nucleic acids research 2000;28(1):364-8.
2000: Michiyo Okui; F Ito; K Ogita; N Kuramoto; Jun Kudoh; Nobuyoshi Shimizu; T Ide
Expression of APG-2 protein, a member of the heat shock protein 110 family, in developing rat brain.
Neurochemistry international 2000;36(1):35-43.
1999: Tohru Kitada; Shuichi Asakawa; Hiroto Matsumine; Nobutaka Hattori; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno
Positional cloning of the autosomal recessive juvenile parkinsonism (AR-JP) gene and its diversity in deletion mutations.
Parkinsonism & related disorders 1999;5(4):163-8.
1999: Michiyo Okui; T Ide; K Morita; Eishi Funakoshi; F Ito; K Ogita; Y Yoneda; Jun Kudoh; Nobuyoshi Shimizu
High-level expression of the Mnb/Dyrk1A gene in brain and heart during rat early development.
Genomics 1999;62(2):165-71.
1999: Mikio Kato; A Kato; Nobuyoshi Shimizu
A method for evaluating phylogenetic relationship of alpha-satellite DNA suprachromosomal family by nucleotide frequency calculation.
Molecular phylogenetics and evolution 1999;13(2):329-35.
1999: A Nagasawa; Jun Kudoh; Setsuko Noda; Y Mashima; A Wright; Y Oguchi; Nobuyoshi Shimizu
Human and mouse ISLR (immunoglobulin superfamily containing leucine-rich repeat) genes: genomic structure and tissue expression.
Genomics 1999;61(1):37-43.
1999: M Sumitomo; Masaaki Tachibana; Masaru Murai; M Hayakawa; H Nakamura; Atsushi Takayanagi; Nobuyoshi Shimizu
Overexpression of IL-1ra gene up-regulates interleukin-1beta converting enzyme (ICE) gene expression: possible mechanism underlying IL-1beta-resistance of cancer cells.
British journal of cancer 1999;81(2):277-86.
1999: Nobuyoshi Shimizu; Shinsei Minoshima; Shuichi Asakawa
[Cloning of Parkin gene and its function].
Nō to shinkei = Brain and nerve 1999;51(6):487-91.
1999: Hideki Shimura; Nobutaka Hattori; S i Kubo; M Yoshikawa; Tohru Kitada; Hiroto Matsumine; Shuichi Asakawa; Shinsei Minoshima; Yasuhiro Yamamura; Nobuyoshi Shimizu; Yoshikuni Mizuno
Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients.
Annals of neurology 1999;45(5):668-72.
1999: M Wang; Nobutaka Hattori; Hiroto Matsumine; Tomonori Kobayashi; Hiroyo Yoshino; A Morioka; Tohru Kitada; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno
Polymorphism in the parkin gene in sporadic Parkinson's disease.
Annals of neurology 1999;45(5):655-8.
1999: M Heino; Pärt Peterson; Jun Kudoh; Kentaro Nagamine; Anssi Lagerstedt; Vladimir Ovod; Annamari Ranki; Immo Rantala; M Nieminen; J Tuukkanen; Hamish Scott; Stylianos E Antonarakis; Nobuyoshi Shimizu; Kai Krohn
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.
Biochemical and biophysical research communications 1999;257(3):821-5.
1999: Y Ohtake; J Chen; Shinobu Gamou; Atsushi Takayanagi; Y Mashima; Y Oguchi; Nobuyoshi Shimizu
Ex vivo delivery of suicide genes into melanoma cells using epidermal growth factor receptor-specific Fab immunogene.
Japanese journal of cancer research : Gann 1999;90(4):460-8.
1999: L Mittaz; Colette Rossier; M Heino; Pärt Peterson; KJ Krohn; A Gos; Michael Morris; Jun Kudoh; Nobuyoshi Shimizu; Stylianos E Antonarakis; Hamish Scott
Isolation and characterization of the mouse Aire gene.
Biochemical and biophysical research communications 1999;255(2):483-90.
1999: Yukihiko Mashima; K Shinoda; S Ishida; Y Ozawa; Jun Kudoh; Takeshi Iwata; Yoshihisa Oguchi; Nobuyoshi Shimizu
Identification of four novel mutations of the XLRS1 gene in Japanese patients with X-linked juvenile retinoschisis. Mutation in brief no. 234. Online.
Human mutation 1999;13(4):338.
1999: M Sumitomo; M Tachibana; C Ozu; H Asakura; Masaru Murai; M Hayakawa; H Nakamura; Atsushi Takayanagi; Nobuyoshi Shimizu
Induction of apoptosis of cytokine-producing bladder cancer cells by adenovirus-mediated IkappaBalpha overexpression.
Human gene therapy 1999;10(1):37-47.
1999: Yukihiko Mashima; Y Nakamura; K Noda; M Konishi; Masakazu Yamada; Jun Kudoh; Nobuyoshi Shimizu
A novel mutation at codon 124 (R124L) in the BIGH3 gene is associated with a superficial variant of granular corneal dystrophy.
Archives of ophthalmology 1999;117(1):90-3.
1999: M Heino; Hamish Scott; Q Chen; Pärt Peterson; U Mäebpää; MP Papasavvas; L Mittaz; C Barras; Colette Rossier; George Chrousos; Constantine Straturis; Kentaro Nagamine; Jun Kudoh; Nobuyoshi Shimizu; N Maclaren; Stylianos E Antonarakis; Kai Krohn
Mutation analyses of North American APS-1 patients.
Human mutation 1999;13(1):69-74.
1999: Shinsei Minoshima; S Mitsuyama; S Ohno; Takeshi Kawamura; Nobuyoshi Shimizu
Keio Mutation Database for eye disease genes (KMeyeDB).
Nucleic acids research 1999;27(1):358-61.
1998: J Chen; Shinobu Gamou; Atsushi Takayanagi; Y Ohtake; Masafumi Ohtsubo; Nobuyoshi Shimizu
Targeted in vivo delivery of therapeutic gene into experimental squamous cell carcinomas using anti-epidermal growth factor receptor antibody: immunogene approach.
Human gene therapy 1998;9(18):2673-81.
1998: Nobutaka Hattori; Tohru Kitada; Hiroto Matsumine; Shuichi Asakawa; Yasuhiro Yamamura; Hiroyo Yoshino; Tomonori Kobayashi; Masayuki Yokochi; M Wang; A Yoritaka; Tomoyoshi Kondo; S Kuzuhara; S Nakamura; Nobuyoshi Shimizu; Yoshikuni Mizuno
Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the Parkin gene in affected individuals.
Annals of neurology 1998;44(6):935-41.
1998: Kentaro Nagamine; Jun Kudoh; Shinsei Minoshima; K Kawasaki; Shuichi Asakawa; F Ito; Nobuyoshi Shimizu
Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain.
Genomics 1998;54(1):124-31.
1998: Yukihiko Mashima; M Konishi; Y Nakamura; Y Imamura; Masakazu Yamada; T Ogata; Jun Kudoh; Nobuyoshi Shimizu
Severe form of juvenile corneal stromal dystrophy with homozygous R124H mutation in the keratoepithelin gene in five Japanese patients.
The British journal of ophthalmology 1998;82(11):1280-4.
1998: J Chen; Shinobu Gamou; Atsushi Takayanagi; Y Ohtake; Masafumi Ohtsubo; Nobuyoshi Shimizu
Receptor-mediated gene delivery using the Fab fragments of anti-epidermal growth factor receptor antibodies: improved immunogene approach.
Cancer gene therapy 1998;5(6):357-64.
1998: N Itoh; Nobuyoshi Shimizu
DNA replication-dependent intranuclear relocation of double minute chromatin.
Journal of cell science 1998;111 ( Pt 22)():3275-85.
1998: Maria Cristina Rosatelli; meloni alessandra; A Meloni; M Devoto; Antonio Cao; Hamish Scott; Pärt Peterson; M Heino; KJ Krohn; Kentaro Nagamine; Jun Kudoh; Nobuyoshi Shimizu; Stylianos E Antonarakis
A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients.
Human genetics 1998;103(4):428-34.
1998: Michel Guipponi; Hamish Scott; Jun Kudoh; K Kawasaki; Kazunori Shibuya; A Shintani; Shuichi Asakawa; H Chen; Maria D Lalioti; Colette Rossier; Shinsei Minoshima; Nobuyoshi Shimizu; Stylianos E Antonarakis
Identification and characterization of a novel cyclic nucleotide phosphodiesterase gene (PDE9A) that maps to 21q22.3: alternative splicing of mRNA transcripts, genomic structure and sequence.
Human genetics 1998;103(4):386-92.
1998: Jun Wang; Jun Kudoh; A Shintani; Shinsei Minoshima; Nobuyoshi Shimizu
Identification of two novel 5' noncoding exons in human MNB/DYRK gene and alternatively spliced transcripts.
Biochemical and biophysical research communications 1998;250(3):704-10.
1998: Pärt Peterson; Kentaro Nagamine; H Scott; M Heino; Jun Kudoh; Nobuyoshi Shimizu; Stylianos E Antonarakis; KJ Krohn
APECED: a monogenic autoimmune disease providing new clues to self-tolerance.
Immunology today 1998;19(9):384-6.
1998: M Konishi; Yukihiko Mashima; Masakazu Yamada; Jun Kudoh; Nobuyoshi Shimizu
The classic form of granular corneal dystrophy associated with R555W mutation in the BIGH3 gene is rare in Japanese patients.
American journal of ophthalmology 1998;126(3):450-2.
1998: Nobutaka Hattori; Hiroto Matsumine; Shuichi Asakawa; Tohru Kitada; Hiroyo Yoshino; B Elibol; A J Brookes; Yasuhiro Yamamura; Tomonori Kobayashi; M Wang; A Yoritaka; Shinsei Minoshima; Nobuyoshi Shimizu; Yoshikuni Mizuno
Point mutations (Thr240Arg and Gln311Stop) [correction of Thr240Arg and Ala311Stop] in the Parkin gene.
Biochemical and biophysical research communications 1998;249(3):754-8.
1998: Hamish Scott; M Heino; Pärt Peterson; L Mittaz; Maria D Lalioti; C Betterle; A Cohen; M Seri; M Lerone; Giovanni Romeo; P Collin; M Salo; Russell A Metcalfe; Anthony P Weetman; MP Papasavvas; Colette Rossier; Kentaro Nagamine; Jun Kudoh; Nobuyoshi Shimizu; KJ Krohn; Stylianos E Antonarakis
Common mutations in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients of different origins.
Molecular endocrinology (Baltimore, Md.) 1998;12(8):1112-9.
1998: Y Imamura; Setsuko Noda; Y Mashima; Jun Kudoh; Y Oguchi; Nobuyoshi Shimizu
Human retina-specific amine oxidase: genomic structure of the gene (AOC2), alternatively spliced variant, and mRNA expression in retina.
Genomics 1998;51(2):293-8.
1998: H Takahashi; Setsuko Noda; Y Imamura; A Nagasawa; R Kubota; Y Mashima; Jun Kudoh; Y Oguchi; Nobuyoshi Shimizu
Mouse myocilin (Myoc) gene expression in ocular tissues.
Biochemical and biophysical research communications 1998;248(1):104-9.
1998: Rumiko Matsuoka; Misa Kimura; P J Scambler; Bernice E Morrow; Shinichiro Imamura; Shinsei Minoshima; Nobuyoshi Shimizu; H Yamagishi; Kunitaka Joh-o; S Watanabe; K Oyama; T Saji; Masahiko Ando; Atsuyoshi Takao; Kazuo Momma
Molecular and clinical study of 183 patients with conotruncal anomaly face syndrome.
Human genetics 1998;103(1):70-80.
1998: H Nakamura; T Oda; Koichi Hamada; Tetsuo Hirano; Nobuyoshi Shimizu; Hiroyasu Utiyama
Survival by Mac-1-mediated adherence and anoikis in phorbol ester-treated HL-60 cells.
The Journal of biological chemistry 1998;273(25):15345-51.
1998: Mikio Kato; K Matsunaga; Nobuyoshi Shimizu
A novel unusual DNA structure formed in an inverted repeat sequence.
Biochemical and biophysical research communications 1998;246(2):532-4.
1998: Shuichi Asakawa; Nobuyoshi Shimizu
High-fidelity digital hybridization screening.
Genomics 1998;49(2):209-17.
1998: Tohru Kitada; Shuichi Asakawa; Nobutaka Hattori; Hiroto Matsumine; Yasuhiro Yamamura; Shinsei Minoshima; Masayuki Yokochi; Yoshikuni Mizuno; Nobuyoshi Shimizu
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
Nature 1998;392(6676):605-8.
1998: Yukihiko Mashima; Kyoko Yamada; M Wakakura; K Kigasawa; Jun Kudoh; Nobuyoshi Shimizu; Yoshihisa Oguchi
Spectrum of pathogenic mitochondrial DNA mutations and clinical features in Japanese families with Leber's hereditary optic neuropathy.
Current eye research 1998;17(4):403-8.
1998: Koichi Hamada; H Nakamura; T Oda; Tetsuo Hirano; Nobuyoshi Shimizu; Hiroyasu Utiyama
Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells.
Biochemical and biophysical research communications 1998;244(3):745-50.
1998: Nobuyoshi Shimizu; N Itoh; Hiroyasu Utiyama; G M Wahl
Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase.
The Journal of cell biology 1998;140(6):1307-20.
1998: Atsushi Takayanagi; J Chen; Shinobu Gamou; Nobuyoshi Shimizu
[Targeting delivery of therapeutic genes using monoclonal antibody; immunogene approach].
Nihon rinsho. Japanese journal of clinical medicine 1998;56(3):731-6.
1998: Masamichi Saga; Yukihiko Mashima; Kiyoshi Akeo; Jun Kudoh; Yoshihisa Oguchi; Nobuyoshi Shimizu
A novel homozygous Ile535Asn mutation in the rod cGMP phosphodiesterase beta-subunit gene in two brothers of a Japanese family with autosomal recessive retinitis pigmentosa.
Current eye research 1998;17(3):332-5.
1998: Masafumi Ohtsubo; Shinobu Gamou; Nobuyoshi Shimizu
Antisense oligonucleotide of WAF1 gene prevents EGF-induced cell-cycle arrest in A431 cells.
Oncogene 1998;16(6):797-802.
1998: R Kubota; Jun Kudoh; Y Mashima; Shuichi Asakawa; Shinsei Minoshima; J F Hejtmancik; Y Oguchi; Nobuyoshi Shimizu
Genomic organization of the human myocilin gene (MYOC) responsible for primary open angle glaucoma (GLC1A).
Biochemical and biophysical research communications 1998;242(2):396-400.
1998: Takahiro Nakayama; Rumiko Matsuoka; Misa Kimura; Hamao Hirota; Katsuhiko Mikoshiba; Y Shimizu; Nobuyoshi Shimizu; Kimio Akagawa
Hemizygous deletion of the HPC-1/syntaxin 1A gene (STX1A) in patients with Williams syndrome.
Cytogenetics and cell genetics 1998;82(1-2):49-51.
1997: Shinsei Minoshima; Nobuyoshi Shimizu
[Genome information database].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(17 Suppl):3038-45.
1997: Nobuyoshi Shimizu; J Kudoh; Shinsei Minoshima; K Kawasaki; S Asakawa
[Physical mapping of disease-associated regions and functional analysis of pathogenic genes: gene hunting by genomic DNA sequencing and cDNA screening].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(17 Suppl):2729-36.
1997: Kentaro Nagamine; Pärt Peterson; Hamish Scott; Jun Kudoh; Shinsei Minoshima; M Heino; KJ Krohn; Maria D Lalioti; P E Mullis; Stylianos E Antonarakis; K Kawasaki; Shuichi Asakawa; F Ito; Nobuyoshi Shimizu
Positional cloning of the APECED gene.
Nature genetics 1997;17(4):393-8.
1997: A Nagasawa; R Kubota; Y Imamura; Kentaro Nagamine; Y Wang; Shuichi Asakawa; Jun Kudoh; Shinsei Minoshima; Y Mashima; Y Oguchi; Nobuyoshi Shimizu
Cloning of the cDNA for a new member of the immunoglobulin superfamily (ISLR) containing leucine-rich repeat (LRR).
Genomics 1997;44(3):273-9.
1997: Ken Ishii; Masayuki Amagai; R P Hall; Takashi Hashimoto; Atsushi Takayanagi; Shinobu Gamou; Nobuyoshi Shimizu; Takeji Nishikawa
Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):2010-7.
1997: Kentaro Nagamine; Jun Kudoh; Shinsei Minoshima; K Kawasaki; Shuichi Asakawa; F Ito; Nobuyoshi Shimizu
Genomic organization and complete nucleotide sequence of the human PWP2 gene on chromosome 21.
Genomics 1997;42(3):528-31.
1997: Kentaro Nagamine; Jun Kudoh; K Kawasaki; Shinsei Minoshima; Shuichi Asakawa; F Ito; Nobuyoshi Shimizu
Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3.
Biochemical and biophysical research communications 1997;235(1):185-90.
1997: R Chrast; Hamish Scott; Haiming Chen; Jun Kudoh; Colette Rossier; Shinsei Minoshima; Y Wang; Nobuyoshi Shimizu; Stylianos E Antonarakis
Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.
Genome research 1997;7(6):615-24.
1997: Shuichi Asakawa; I Abe; Y Kudoh; N Kishi; Y Wang; R Kubota; Jun Kudoh; K Kawasaki; Shinsei Minoshima; Nobuyoshi Shimizu
Human BAC library: construction and rapid screening.
Gene 1997;191(1):69-79.
1997: R Kubota; Setsuko Noda; Y Wang; Shinsei Minoshima; Shuichi Asakawa; Jun Kudoh; Y Mashima; Y Oguchi; Nobuyoshi Shimizu
A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping.
Genomics 1997;41(3):360-9.
1997: Y Imamura; R Kubota; Y Wang; Shuichi Asakawa; Jun Kudoh; Y Mashima; Y Oguchi; Nobuyoshi Shimizu
Human retina-specific amine oxidase (RAO): cDNA cloning, tissue expression, and chromosomal mapping.
Genomics 1997;40(2):277-83.
1997: K Kawasaki; Shinsei Minoshima; E Nakato; K Shibuya; A Shintani; James Schmeits; Jun Wang; Nobuyoshi Shimizu
One-megabase sequence analysis of the human immunoglobulin lambda gene locus.
Genome research 1997;7(3):250-61.
1997: Jun Kudoh; Kentaro Nagamine; Shuichi Asakawa; I Abe; K Kawasaki; H Maeda; S Tsujimoto; Shinsei Minoshima; F Ito; Nobuyoshi Shimizu
Localization of 16 exons to a 450-kb region involved in the autoimmune polyglandular disease type I (APECED) on human chromosome 21q22.3.
DNA research : an international journal for rapid publication of reports on genes and genomes 1997;4(1):45-52.
1996: Nobuyoshi Shimizu
[Prospects of the human chromosome research].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2510-1.
1996: Nobuyoshi Shimizu
[Gene therapy: current status and prospects].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2491-3.
1996: Shinsei Minoshima; Nobuyoshi Shimizu
[Genetic information database].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2464-77.
1996: K Kawasaki; Nobuyoshi Shimizu
[Shotgun sequencing].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2458-63.
1996: Jun Kudoh; Nobuyoshi Shimizu
[Physical mapping of human chromosome].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2414-23.
1996: Shinsei Minoshima; Nobuyoshi Shimizu
[Analysis of disease-associated marker chromosomes using chromosome sorter].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2174-81.
1996: Y Wang; Jun Kudoh; R Kubota; Shuichi Asakawa; Shinsei Minoshima; Nobuyoshi Shimizu
Chromosomal mapping of a family of human glutamine synthetase genes: functional gene (GLUL) on 1q25, pseudogene (GLULP) on 9p13, and three related genes (GLULL1, GLULL2, GLULL3) on 5q33, 11p15, and 11q24.
Genomics 1996;37(2):195-9.
1996: Masayuki Amagai; Ken Ishii; Atsushi Takayanagi; Takeji Nishikawa; Nobuyoshi Shimizu
Transport to endoplasmic reticulum by signal peptide, but not proteolytic processing, is required for formation of conformational epitopes of pemphigus vulgaris antigen (Dsg3).
The Journal of investigative dermatology 1996;107(4):539-42.
1996: Kentaro Nagamine; Jun Kudoh; Shinsei Minoshima; K Kawasaki; Shuichi Asakawa; F Ito; Nobuyoshi Shimizu
Isolation of cDNA for a novel human protein KNP-I that is homologous to the E. coli SCRP-27A protein from the autoimmune polyglandular disease type I (APECED) region of chromosome 21q22.3.
Biochemical and biophysical research communications 1996;225(2):608-16.
1996: N Shindoh; Jun Kudoh; H Maeda; A Yamaki; Shinsei Minoshima; Y Shimizu; Nobuyoshi Shimizu
Cloning of a human homolog of the Drosophila minibrain/rat Dyrk gene from "the Down syndrome critical region" of chromosome 21.
Biochemical and biophysical research communications 1996;225(1):92-9.
1996: A Yamaki; Setsuko Noda; Jun Kudoh; N Shindoh; H Maeda; Shinsei Minoshima; K Kawasaki; Y Shimizu; Nobuyoshi Shimizu
The mammalian single-minded (SIM) gene: mouse cDNA structure and diencephalic expression indicate a candidate gene for Down syndrome.
Genomics 1996;35(1):136-43.
1996: Shinobu Gamou; Nobuyoshi Shimizu
[Expression of EGF receptor subfamily in tumor].
Nihon rinsho. Japanese journal of clinical medicine 1996;54(6):1521-8.
1996: Nobuyoshi Shimizu; J Chen; Shinobu Gamou; Atsushi Takayanagi
Immunogene approach toward cancer therapy using erythrocyte growth factor receptor-mediated gene delivery.
Cancer gene therapy 1996;3(2):113-20.
1995: Shinobu Gamou; J Chen; Atsushi Takayanagi; Nobuyoshi Shimizu
[Gene delivery by immunogene and its application to cancer gene therapy].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1995;40(17):2562-9.
1995: Nobutaka Hattori; H Suzuki; Y Wang; Shinsei Minoshima; Nobuyoshi Shimizu; Hiroyo Yoshino; R Kurashima; M Tanaka; T Ozawa; Yoshikuni Mizuno
Structural organization and chromosomal localization of the human nuclear gene (NDUFV2) for the 24-kDa iron-sulfur subunit of complex I in mitochondrial respiratory chain.
Biochemical and biophysical research communications 1995;216(3):771-7.
1995: K Kawasaki; Shinsei Minoshima; K Schooler; Jun Kudoh; Shuichi Asakawa; P J de Jong; Nobuyoshi Shimizu
The organization of the human immunoglobulin lambda gene locus.
Genome research 1995;5(2):125-35.
1995: Y Wang; Shinsei Minoshima; Nobuyoshi Shimizu
Cot-1 banding of human chromosomes using fluorescence in situ hybridization with Cy3 labeling.
The Japanese journal of human genetics 1995;40(3):243-52.
1995: Masayuki Amagai; Ken Ishii; T Hashimoto; Shinobu Gamou; Nobuyoshi Shimizu; Takeji Nishikawa
Conformational epitopes of pemphigus antigens (Dsg1 and Dsg3) are calcium dependent and glycosylation independent.
The Journal of investigative dermatology 1995;105(2):243-7.
1995: Y Mashima; Masamichi Saga; Y Hiida; Y Oguchi; M Wakakura; Jun Kudoh; Nobuyoshi Shimizu
Quantitative determination of heteroplasmy in Leber's hereditary optic neuropathy by single-strand conformation polymorphism.
Investigative ophthalmology & visual science 1995;36(8):1714-20.
1995: Y Hiida; Y Mashima; Masamichi Saga; M Shuu; S Akiya; Jun Kudoh; Nobuyoshi Shimizu; Y Oguchi
[Molecular genetic analysis of Leber's hereditary optic neuropathy with the 3460 mutation in Japanese pedigrees].
Nippon Ganka Gakkai zasshi 1995;99(6):728-34.
1995: Masayuki Amagai; T Hashimoto; K J Green; Nobuyoshi Shimizu; Takeji Nishikawa
Antigen-specific immunoadsorption of pathogenic autoantibodies in pemphigus foliaceus.
The Journal of investigative dermatology 1995;104(6):895-901.
1995: K Sakai; T Ohta; Shinsei Minoshima; Jun Kudoh; Y Wang; P J de Jong; Nobuyoshi Shimizu
Human ribosomal RNA gene cluster: identification of the proximal end containing a novel tandem repeat sequence.
Genomics 1995;26(3):521-6.
1995: T Hashimoto; Shinobu Gamou; Nobuyoshi Shimizu; Y Kitajima; T Nishikawa
Regulation of translocation of the desmoyokin/AHNAK protein to the plasma membrane in keratinocytes by protein kinase C.
Experimental cell research 1995;217(2):258-66.
1995: R Kubota; Y Wang; Shinsei Minoshima; Jun Kudoh; Y Mashima; Y Oguchi; Nobuyoshi Shimizu
Mapping of the human gene for a melanocyte protein Pmel 17 (D12S53E) to chromosome 12q13-q14.
Genomics 1995;26(2):430-1.
1995: Y Mashima; Y Hiida; Masamichi Saga; Y Oguchi; Jun Kudoh; Nobuyoshi Shimizu
Risk of false-positive molecular genetic diagnosis of Leber's hereditary optic neuropathy.
American journal of ophthalmology 1995;119(2):245-6.
1995: Shinobu Gamou; Nobuyoshi Shimizu
Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor.
FEBS letters 1995;357(2):161-4.
1995: Shinsei Minoshima; Y Wang; K Ichida; T Nishino; Nobuyoshi Shimizu
Mapping of the gene for human xanthine dehydrogenase (oxidase) (XDH) to band p23 of chromosome 2.
Cytogenetics and cell genetics 1995;68(1-2):52-3.
1995: Jun Kudoh; Y Wang; Shinsei Minoshima; T Hashimoto; Masayuki Amagai; Takeji Nishikawa; E Shtivelman; John M Bishop; Nobuyoshi Shimizu
Localization of the human AHNAK/desmoyokin gene (AHNAK) to chromosome band 11q12 by somatic cell hybrid analysis and fluorescence in situ hybridization.
Cytogenetics and cell genetics 1995;70(3-4):218-20.
1995: Masayuki Amagai; Y Wang; Shinsei Minoshima; K Kawamura; K J Green; Takeji Nishikawa; Nobuyoshi Shimizu
Assignment of the human genes for desmocollin 3 (DSC3) and desmocollin 4 (DSC4) to chromosome 18q12.
Genomics 1995;25(1):330-2.
1995: Masayuki Amagai; T Fujimori; Takuji Masunaga; Hiroshi Shimizu; Takeji Nishikawa; Nobuyoshi Shimizu; M Takeichi; T Hashimoto
Delayed assembly of desmosomes in keratinocytes with disrupted classic-cadherin-mediated cell adhesion by a dominant negative mutant.
The Journal of investigative dermatology 1995;104(1):27-32.
1994: N Fujita; S Tamura; Nobuyoshi Shimizu; Shiro Nozawa
Genetic origin analysis of hydatidiform mole and non-molar abortion using the polymerase chain reaction method.
Acta obstetricia et gynecologica Scandinavica 1994;73(9):719-25.
1994: M Dmochowski; T Hashimoto; Masayuki Amagai; Jun Kudoh; Nobuyoshi Shimizu; PJ Koch; W W Franke; Takeji Nishikawa
The extracellular aminoterminal domain of bovine desmoglein 1 (Dsg1) is recognized only by certain pemphigus foliaceus sera, whereas its intracellular domain is recognized by both pemphigus vulgaris and pemphigus foliaceus sera.
The Journal of investigative dermatology 1994;103(2):173-7.
1994: Shinobu Gamou; Nobuyoshi Shimizu
Light-dependent induction of early-response gene expression by calphostin-C.
Cell structure and function 1994;19(4):195-200.
1994: Masayuki Amagai; T Hashimoto; Nobuyoshi Shimizu; Takeji Nishikawa
Absorption of pathogenic autoantibodies by the extracellular domain of pemphigus vulgaris antigen (Dsg3) produced by baculovirus.
The Journal of clinical investigation 1994;94(1):59-67.
1994: Nobuyoshi Shimizu; H Nakamura; T Kadota; K Kitajima; T Oda; Tetsuo Hirano; Hiroyasu Utiyama
Loss of amplified c-myc genes in the spontaneously differentiated HL-60 cells.
Cancer research 1994;54(13):3561-7.
1994: Nobuyoshi Shimizu; Y Wang; S Minoshima; J Ishitoya
Detection of epidermal growth factor receptor gene amplification in human squamous cell carcinomas using fluorescence in situ hybridization.
Japanese journal of cancer research : Gann 1994;85(6):567-71.
1994: Masamichi Saga; Y Mashima; Kiyoshi Akeo; Y Oguchi; Jun Kudoh; Nobuyoshi Shimizu
Autosomal dominant retinitis pigmentosa. A mutation in codon 181 (Glu-->Lys) of the rhodopsin gene in a Japanese family.
Ophthalmic genetics 1994;15(2):61-7.
1994: Y Wang; Masayuki Amagai; Shinsei Minoshima; K Sakai; K J Green; Takeji Nishikawa; Nobuyoshi Shimizu
The human genes for desmogleins (DSG1 and DSG3) are located in a small region on chromosome 18q12.
Genomics 1994;20(3):492-5.
1994: J Chen; Shinobu Gamou; Atsushi Takayanagi; Nobuyoshi Shimizu
A novel gene delivery system using EGF receptor-mediated endocytosis.
FEBS letters 1994;338(2):167-9.
1994: Shinobu Gamou; Nobuyoshi Shimizu
Calphostin-C stimulates epidermal growth factor receptor phosphorylation and internalization via light-dependent mechanism.
Journal of cellular physiology 1994;158(1):151-9.
1993: Y Mashima; Y Hiida; R Kubota; Y Oguchi; Jun Kudoh; Nobuyoshi Shimizu
DNA diagnosis of Leber's hereditary optic neuropathy by using dried blood specimens.
American journal of ophthalmology 1993;116(6):773-4.
1993: Y Wang; Shinsei Minoshima; Nobuyoshi Shimizu
Precise mapping of the EGF receptor gene on the human chromosome 7p12 using an improved fish technique.
The Japanese journal of human genetics 1993;38(4):399-406.
1993: Nobuyoshi Shimizu; Shinsei Minoshima; Jun Kudoh; K Kawasaki; Y Wang; Y Shimizu; K Sakai
Human gene mapping and chromosome sorting by laser technology.
The Keio journal of medicine 1993;42(4):212-6.
1993: Masamichi Saga; Y Mashima; Kiyoshi Akeo; Y Oguchi; Jun Kudoh; Nobuyoshi Shimizu
A novel Cys-214-Ser mutation in the peripherin/RDS gene in a Japanese family with autosomal dominant retinitis pigmentosa.
Human genetics 1993;92(5):519-21.
1993: M Toda; T Shirao; Shinsei Minoshima; Nobuyoshi Shimizu; S Toya; Keiichi Uyemura
Molecular cloning of cDNA encoding human drebrin E and chromosomal mapping of its gene.
Biochemical and biophysical research communications 1993;196(1):468-72.
1993: Shinsei Minoshima; Nobuyoshi Shimizu
[Application of the chromosome sorting technique to the human genome analysis].
Nihon rinsho. Japanese journal of clinical medicine 1993;51(9):2234-9.
1993: T Oda; K Kitajima; Tetsuo Hirano; Nobuyoshi Shimizu; Hiroyasu Utiyama
Interplay between differentiation and cell cycle arrest at G1 in phorbol diester-treated human myelocytic leukemia cells.
International journal of hematology 1993;58(1-2):125-8.
1993: Y Mashima; Y Hiida; Y Oguchi; Jun Kudoh; Nobuyoshi Shimizu
High frequency of mutations at position 11778 in mitochondrial ND4 gene in Japanese families with Leber's hereditary optic neuropathy.
Human genetics 1993;92(1):101-2.
1993: T Hashimoto; Masayuki Amagai; T Ebihara; Shinobu Gamou; Nobuyoshi Shimizu; T Tsubata; A Hasegawa; K Miki; Takeji Nishikawa
Further analyses of epitopes for human monoclonal anti-basement membrane zone antibodies produced by stable human hybridoma cell lines constructed with Epstein-Barr virus transformants.
The Journal of investigative dermatology 1993;100(3):310-5.
1993: Nobuyoshi Shimizu; Shinsei Minoshima; Jun Kudoh; K Kawasaki
[Human genome analysis using chromosome sorting].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1993;38(3):268-77.
1993: T Ebihara; T Hashimoto; Jun Kudoh; Shinobu Gamou; Nobuyoshi Shimizu; Takeji Nishikawa
Detection of the 170-kDa bullous pemphigoid antigen by immunoprecipitation.
The Journal of investigative dermatology 1993;100(2):176-9.
1992: Nobuyoshi Shimizu
[Applications of flow cytometry to molecular biology and molecular genetics].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(10):2319-23.
1992: K Sakai; M Hirai; Jun Kudoh; Shinsei Minoshima; Nobuyoshi Shimizu
Molecular cloning and chromosomal mapping of a cDNA encoding human 80K-L protein: major substrate for protein kinase C.
Genomics 1992;14(1):175-8.
1992: Shinobu Gamou; Nobuyoshi Shimizu
[Epidermal growth factor and its receptor: the structure and function].
Nihon rinsho. Japanese journal of clinical medicine 1992;50(8):1885-92.
1992: R Fukuyama; Nobuyoshi Shimizu
Detection of variation in the ribosomal RNA gene clusters by a modified fluorescence in situ hybridization method.
The Japanese journal of human genetics 1992;37(2):139-43.
1992: Nobuyoshi Shimizu; M Ohta; C Fujiwara; J Sagara; N Mochizuki; T Oda; Hiroyasu Utiyama
A gene coding for a zinc finger protein is induced during 12-O-tetradecanoylphorbol-13-acetate-stimulated HL-60 cell differentiation.
Journal of biochemistry 1992;111(2):272-7.
1992: K Kawasaki; Shinsei Minoshima; Jun Kudoh; R Fukuyama; Nobuyoshi Shimizu
Methylation status of ribosomal RNA gene clusters in the flow-sorted human acrocentric chromosomes.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;3(3):173-8.
1992: K Oguro; K Sakamoto; K Kitajima; T Oda; Tetsuo Hirano; Nobuyoshi Shimizu; Hiroyasu Utiyama
Determination of transcriptional activities of typical gene promoters in HL-60 cells.
Journal of biochemistry 1992;111(1):103-8.
1991: M Osaku; Masakazu Ueda; Nobutoshi Ando; Yotaro Shinozawa; N Hirota; Nobuyoshi Shimizu; O Abe
Targeted killing of squamous carcinoma cells by a monoclonal antibody-peplomycin conjugate which recognizes the EGF receptor.
Anticancer research 1991;11(6):1951-6.
1991: M Tanaka; T Hashimoto; Masayuki Amagai; Nobuyoshi Shimizu; N Ikeguchi; T Tsubata; A Hasegawa; K Miki; Takeji Nishikawa
Characterization of bullous pemphigoid antibodies by use of recombinant bullous pemphigoid antigen proteins.
The Journal of investigative dermatology 1991;97(4):725-8.
1991: R Fukuyama; Y Ichijoh; Shinsei Minoshima; N Kitamura; Nobuyoshi Shimizu
Regional localization of the hepatocyte growth factor (HGF) gene to human chromosome 7 band q21.1.
Genomics 1991;11(2):410-5.
1991: T Okuyama; N Matsuo; Jun Kudoh; Nobuyoshi Shimizu
A ScrFI polymorphism in the human ALPL gene.
Nucleic acids research 1991;19(18):5090.
1991: Nobuyoshi Shimizu; M Ohta; C Fujiwara; J Sagara; N Mochizuki; T Oda; Hiroyasu Utiyama
Expression of a novel immediate early gene during 12-O-tetradecanoylphorbol-13-acetate-induced macrophagic differentiation of HL-60 cells.
The Journal of biological chemistry 1991;266(19):12157-61.
1991: R Fukuyama; M Takata; Jun Kudoh; K Sakai; S Tamura; Nobuyoshi Shimizu
DNA diagnosis of hydatidiform mole using the polymerase chain reaction.
Human genetics 1991;87(2):216-8.
1991: R Fukuyama; Nobuyoshi Shimizu
Expression of epidermal growth factor (EGF) and the EGF receptor in human tissues.
The Journal of experimental zoology 1991;258(3):336-43.
1991: Shinobu Gamou; Nobuyoshi Shimizu
[The regulatory mechanism of EGF receptor gene expression].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):994-1000.
1991: Nobuyoshi Shimizu
[Growth factors: recent advances and perspectives].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):971-7.
1991: Masakazu Ueda; O Abe; Nobuyoshi Shimizu
[Targeting therapy directed against growth factor receptor].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1436-42.
1991: R Fukuyama; Nobuyoshi Shimizu
[Distribution of growth factor receptors in various human tissues].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1282-91.
1991: M Hirai; Nobuyoshi Shimizu
[Roles of protein kinase C substrates in signal transduction].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1049-55.
1991: K Araki; N Matsuo; J Kodoh; Nobuyoshi Shimizu
RFLPs at the PAH (phenylalanine hydroxylase) gene in the Japanese population.
Nucleic acids research 1991;19(8):1960.
1991: R Fukuyama; Shinsei Minoshima; A Ochiai; E Tahara; Nobuyoshi Shimizu
Flow cytometric analysis of the expression of 9A3 antigen, E-cadherin and EGF receptor in TMK-1 stomach cancer cells.
International journal of cancer. Journal international du cancer 1991;48(1):81-4.
1991: T Okuyama; N Matsuo; Jun Kudoh; Nobuyoshi Shimizu
PCR detection of a BclI RFLP in the human ALPL gene.
Nucleic acids research 1991;19(5):1166.
1991: Y Kitagawa; Masakazu Ueda; Nobutoshi Ando; Yotaro Shinozawa; Nobuyoshi Shimizu; O Abe
Significance of int-2/hst-1 coamplification as a prognostic factor in patients with esophageal squamous carcinoma.
Cancer research 1991;51(5):1504-8.
1991: Shinichiro Nanko; M Kobayashi; Shinobu Gamou; Jun Kudoh; Nobuyoshi Shimizu; N Takazawa; H Kazamatsuri; T Furusho
Linkage analysis of affective disorder using DNA markers on chromosomes 11 and X.
The Japanese journal of psychiatry and neurology 1991;45(1):53-6.
1991: R Fukuyama; Nobuyoshi Shimizu
Detection of epidermal growth factor receptors and E-cadherins in the basolateral membrane of A431 cells by laser scanning fluorescence microscopy.
Japanese journal of cancer research : Gann 1991;82(1):8-11.
1991: Y Hiida; Y Mashima; Y Oguchi; Y Uemura; Jun Kudoh; K Sakai; Nobuyoshi Shimizu
Mitochondrial DNA analysis of Leber's hereditary optic neuropathy.
Japanese journal of ophthalmology 1991;35(1):102-6.
1991: Shinsei Minoshima; Masayuki Amagai; Jun Kudoh; R Fukuyama; T Hashimoto; Takeji Nishikawa; Nobuyoshi Shimizu
Localization of the human gene for 230-kDal bullous pemphigoid autoantigen (BPAG1) to chromosome 6pter----q15.
Cytogenetics and cell genetics 1991;57(1):30-2.
1990: Masayuki Amagai; T Hashimoto; S Tajima; Y Inokuchi; Nobuyoshi Shimizu; M Saito; K Miki; Takeji Nishikawa
Partial cDNA cloning of the 230-kD mouse bullous pemphigoid antigen by use of a human monoclonal anti-basement membrane zone antibody.
The Journal of investigative dermatology 1990;95(3):252-9.
1990: Shinobu Gamou; Nobuyoshi Shimizu
[Growth factors and cell transformation].
Nihon rinsho. Japanese journal of clinical medicine 1990;48(8):111-8.
1990: Shinobu Gamou; Y Shimosato; Nobuyoshi Shimizu
Regulation of the epidermal growth factor receptor gene expression in a morphological variant isolated from an epidermal growth factor receptor-deficient small cell lung carcinoma cell line.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1990;1(8):351-9.
1990: Y Mashima; Y Oguchi; Y Uemura; Jun Kudoh; K Sakai; Nobuyoshi Shimizu
[DNA diagnosis of Leber's hereditary optic neuropathy].
Nippon Ganka Gakkai zasshi 1990;94(7):683-7.
1990: A Kikuchi; M Amagai; K Hayakawa; M Ueda; S Hirohashi; Nobuyoshi Shimizu; Takeji Nishikawa
Association of EGF receptor expression with proliferating cells and of ras p21 expression with differentiating cells in various skin tumours.
The British journal of dermatology 1990;123(1):49-58.
1990: Shinsei Minoshima; K Kawasaki; R Fukuyama; M Maekawa; Jun Kudoh; Nobuyoshi Shimizu
Isolation of giant DNA fragments from flow-sorted human chromosomes.
Cytometry 1990;11(4):539-46.
1990: M Amagai; K Hayakawa; N Amagai; K Kobayashi; Y Onodera; Nobuyoshi Shimizu; Takeji Nishikawa
T cell receptor gene rearrangement analysis in mycosis fungoides and disseminated lymphocytoma cutis.
Dermatologica 1990;181(3):193-6.
1989: T Yanagawa; T Maruyama; Izumi Takei; Y Asaba; T Takahashi; T Ishii; K Kataoka; Takao Saruta; S Minoshima; Nobuyoshi Shimizu
The suppressive effect of cyclophosphamide on low-dose streptozotocin-induced diabetes in mice.
Diabetes research (Edinburgh, Scotland) 1989;12(2):79-83.
1989: M Ueda; Nobuyoshi Shimizu; O Abe
[Amplification and expression of oncogenes in human malignant tumors--organ or tissue specificity and prognosis].
Nihon Geka Gakkai zasshi 1989;90(9):1579-81.
1989: K Sakai; M Hirai; Shinsei Minoshima; Jun Kudoh; R Fukuyama; Nobuyoshi Shimizu
Isolation of cDNAs encoding a substrate for protein kinase C: nucleotide sequence and chromosomal mapping of the gene for a human 80K protein.
Genomics 1989;5(2):309-15.
1989: Shinobu Gamou; M Shimagaki; Shinsei Minoshima; S Kobayashi; Nobuyoshi Shimizu
Subcellular localization of the EGF receptor maturation process.
Experimental cell research 1989;183(1):197-206.
1989: Shinobu Gamou; M Kobayashi; T Furusho; Nobuyoshi Shimizu
Unique chromosomal location of amplified EGF receptor genes in EGF receptor-hyperproducing tumor cell line NA.
Somatic cell and molecular genetics 1989;15(2):179-84.
1989: Masayuki Amagai; Y Inokuchi; Takeji Nishikawa; Y Shimizu; Nobuyoshi Shimizu
Cloning of TPA-inducible early (TIE) genes by differential hybridization using TPA-nonresponsive variant of mouse 3T3-L1 cells.
Somatic cell and molecular genetics 1989;15(2):153-8.
1989: M Hirai; Shinobu Gamou; M Kobayashi; Nobuyoshi Shimizu
Lung cancer cells often express high levels of protein kinase C activity.
Japanese journal of cancer research : Gann 1989;80(3):204-8.
1989: Soji Ozawa; Masakazu Ueda; Nobutoshi Ando; O Abe; Shinsei Minoshima; Nobuyoshi Shimizu
Selective killing of squamous carcinoma cells by an immunotoxin that recognizes the EGF receptor.
International journal of cancer. Journal international du cancer 1989;43(1):152-7.
1988: M Amagai; S Ozawa; M Ueda; Takeji Nishikawa; O Abe; Nobuyoshi Shimizu
Distribution of EGF receptor expressing and DNA replicating epidermal cells in psoriasis vulgaris and Bowen's disease.
The British journal of dermatology 1988;119(5):661-8.
1988: S Ozawa; Masakazu Ueda; N Ando; O Abe; Nobuyoshi Shimizu
Epidermal growth factor receptors in cancer tissues of esophagus, lung, pancreas, colorectum, breast and stomach.
Japanese journal of cancer research : Gann 1988;79(11):1201-7.
1988: K Kawasaki; J Kudoh; K Omoto; Nobuyoshi Shimizu
Mega base map of the epidermal growth factor (EGF) receptor gene flanking regions and structure of the amplification units in EGF receptor-hyperproducing squamous carcinoma cells.
Japanese journal of cancer research : Gann 1988;79(11):1174-83.
1988: Shinobu Gamou; Nobuyoshi Shimizu
Glycosylation of the epidermal growth factor receptor and its relationship to membrane transport and ligand binding.
Journal of biochemistry 1988;104(3):388-96.
1988: Shinobu Gamou; Y Shimosato; G T Merlino; Nobuyoshi Shimizu
Methylation status of epidermal growth factor receptor gene in lung carcinoma cells.
Japanese journal of cancer research : Gann 1988;79(9):989-95.
1988: M Hirai; Shinobu Gamou; S Minoshima; Nobuyoshi Shimizu
Two independent mechanisms for escaping epidermal growth factor-mediated growth inhibition in epidermal growth factor receptor-hyperproducing human tumor cells.
The Journal of cell biology 1988;107(2):791-9.
1988: Shinobu Gamou; M Hirai; K Rikimaru; S Enomoto; Nobuyoshi Shimizu
Biosynthesis of the epidermal growth factor receptor in human squamous cell carcinoma lines: secretion of the truncated receptor is not common to epidermal growth factor receptor-hyperproducing cells.
Cell structure and function 1988;13(1):25-38.
1987: Soji Ozawa; Masakazu Ueda; Nobutoshi Ando; O Abe; M Hirai; Nobuyoshi Shimizu
Stimulation by EGF of the growth of EGF receptor-hyperproducing tumor cells in athymic mice.
International journal of cancer. Journal international du cancer 1987;40(5):706-10.
1978: K Satoh; Nobuyoshi Shimizu; Masaya Tohyama; Takashi Maeda
Localization of the micturition reflex center at dorsolateral pontine tegmentum of the rat.
Neuroscience letters 1978;8(1):27-33.
1978: K Satoh; Masaya Tohyama; T Sakumoto; Koji Yamamoto; Nobuyoshi Shimizu
Descending projection of the nucleus tegmentalis latero-dorsalis to the spinal cord; studied by the horseradish peroxidase method following 6-hydroxy-DOPA administration.
Neuroscience letters 1978;8(1):9-15.