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Nobuyoshi Shimizu

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Concepts & Ideas

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequence

Procedures

Living Beings

Oryzias
Mice

Physiology

Mutation

Anatomy

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Publications

TOP 3
Omasa Takeshi; Cao Yihua; Park Joon Young; Takagi Yasuhiro; Kimura Shuichi; Yano Hidenori; Honda Kohsuke; Asakawa Shuichi; Shimizu Nobuyoshi; Ohtake Hisao
Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells.
Asakawa Shuichi; Hattori Nobutaka; Shimizu Atsushi; Shimizu Yoshiko; Minoshima Shinsei; Mizuno Yoshikuni; Shimizu Nobuyoshi
Analysis of eighteen deletion breakpoints in the parkin gene.
Iwanami Norimasa; Okada Minoru; Hoa Vu Q; Seo Yasuhito; Mitani Hiroshi; Sasaki Takashi; Shimizu Nobuyoshi; Kondoh Hisato; Furutani-Seiki Makoto; Takahama Yousuke
Ethylnitrosourea-induced thymus-defective mutants identify roles of KIAA1440, TRRAP, and SKIV2L2 in teleost organ development.

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All Publications

2009: Omasa Takeshi; Cao Yihua; Park Joon Young; Takagi Yasuhiro; Kimura Shuichi; Yano Hidenori; Honda Kohsuke; Asakawa Shuichi; Shimizu Nobuyoshi; Ohtake Hisao
Bacterial artificial chromosome library for genome-wide analysis of Chinese hamster ovary cells.
Biotechnology and bioengineering 2009;104(5):986-94.
2009: Asakawa Shuichi; Hattori Nobutaka; Shimizu Atsushi; Shimizu Yoshiko; Minoshima Shinsei; Mizuno Yoshikuni; Shimizu Nobuyoshi
Analysis of eighteen deletion breakpoints in the parkin gene.
Biochemical and biophysical research communications 2009;389(1):181-6.
2009: Iwanami Norimasa; Okada Minoru; Hoa Vu Q; Seo Yasuhito; Mitani Hiroshi; Sasaki Takashi; Shimizu Nobuyoshi; Kondoh Hisato; Furutani-Seiki Makoto; Takahama Yousuke
Ethylnitrosourea-induced thymus-defective mutants identify roles of KIAA1440, TRRAP, and SKIV2L2 in teleost organ development.
European journal of immunology 2009;39(9):2606-16.
2009: Saito Masahiro; Nishida Eisaku; Sasaki Takashi; Yoneda Toshiyuki; Shimizu Nobuyoshi
The KK-Periome database for transcripts of periodontal ligament development.
Journal of experimental zoology. Part B, Molecular and developmental evolution 2009;312B(5):495-502.
2009: Fallon Padraic G; Sasaki Takashi; Sandilands Aileen; Campbell Linda E; Saunders Sean P; Mangan Niamh E; Callanan John J; Kawasaki Hiroshi; Shiohama Aiko; Kubo Akiharu; Sundberg John P; Presland Richard B; Fleckman Philip; Shimizu Nobuyoshi; Kudoh Jun; Irvine Alan D; Amagai Masayuki; McLean W H Irwin
A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming.
Nature genetics 2009;41(5):602-8.
2009: Maruyama Satoshi; Cheng Jun; Shingaki Susumu; Tamura Takashi; Asakawa Shuichi; Minoshima Shinsei; Shimizu Yoshiko; Shimizu Nobuyoshi; Saku Takashi
Establishment and characterization of pleomorphic adenoma cell systems: an in-vitro demonstration of carcinomas arising secondarily from adenomas in the salivary gland.
BMC cancer 2009;9():247.
2009: Hashimoto Hisashi; Miyamoto Rieko; Watanabe Naoki; Shiba Dai; Ozato Kenjiro; Inoue Chikako; Kubo Yuko; Koga Akihiko; Jindo Tomoko; Narita Takanori; Naruse Kiyoshi; Ohishi Kazuko; Nogata Keiko; Shin-I Tadasu; Asakawa Shuichi; Shimizu Nobuyoshi; Miyamoto Tomotsune; Mochizuki Toshio; Yokoyama Takahiko; Hori Hiroshi; Takeda Hiroyuki; Kohara Yuji; Wakamatsu Yuko
Polycystic kidney disease in the medaka (Oryzias latipes) pc mutant caused by a mutation in the Gli-Similar3 (glis3) gene.
PloS one 2009;4(7):e6299.
2009: Shimizu N
Extrachromosomal double minutes and chromosomal homogeneously staining regions as probes for chromosome research.
Cytogenetic and genome research 2009;124(3-4):312-26.
2008: Iwanami Norimasa; Higuchi Tomokazu; Sasano Yumi; Fujiwara Toshinobu; Hoa Vu Q; Okada Minoru; Talukder Sadiqur R; Kunimatsu Sanae; Li Jie; Saito Fumi; Bhattacharya Chitralekha; Matin Angabin; Sasaki Takashi; Shimizu Nobuyoshi; Mitani Hiroshi; Himmelbauer Heinz; Momoi Akihiro; Kondoh Hisato; Furutani-Seiki Makoto; Takahama Yousuke
WDR55 is a nucleolar modulator of ribosomal RNA synthesis, cell cycle progression, and teleost organ development.
PLoS genetics 2008;4(8):e1000171.
2008: Sasaki Takashi; Kudoh Jun; Ebihara Tamotsu; Shiohama Aiko; Asakawa Shuichi; Shimizu Atsushi; Takayanagi Atsushi; Dekio Itaru; Sadahira Chieko; Amagai Masayuki; Shimizu Nobuyoshi
Sequence analysis of filaggrin gene by novel shotgun method in Japanese atopic dermatitis.
Journal of dermatological science 2008;51(2):113-20.
2008: Páez Marco T; Yamamoto Toshiyuki; Hayashi Ken-ichi; Yasuda Toshiyuki; Harada Naoki; Matsumoto Naomichi; Kurosawa Kenji; Furutani Yoshiyuki; Asakawa Shuichi; Shimizu Nobuyoshi; Matsuoka Rumiko
Two patients with atypical interstitial deletions of 8p23.1: mapping of phenotypical traits.
American journal of medical genetics. Part A 2008;146A(9):1158-65.
2008: Asai Satoko; Yamaki Akiko; Kudoh Jun; Shimizu Nobuyoshi; Shimizu Yoshiko
Analysis of the promoter region of human placenta-specific DSCR4 gene.
Biochimica et biophysica acta 2008;1779(1):40-50.
2008: Liang Chun-Shi; Ikeda Daisuke; Kinoshita Shigeharu; Shimizu Atsushi; Sasaki Takashi; Asakawa Shuichi; Shimizu Nobuyoshi; Watabe Shugo
Myocyte enhancer factor 2 regulates expression of medaka Oryzias latipes fast skeletal myosin heavy chain genes in a temperature-dependent manner.
Gene 2008;407(1-2):42-53.
2007: Shiohama Aiko; Sasaki Takashi; Noda Setsuko; Minoshima Shinsei; Shimizu Nobuyoshi
Nucleolar localization of DGCR8 and identification of eleven DGCR8-associated proteins.
Experimental cell research 2007;313(20):4196-207.
2007: Lim Meng K; Kawamura Takeshi; Ohsawa Yosuke; Ohtsubo Masafumi; Asakawa Shuichi; Takayanagi Atsushi; Shimizu Nobuyoshi
Parkin interacts with LIM Kinase 1 and reduces its cofilin-phosphorylation activity via ubiquitination.
Experimental cell research 2007;313(13):2858-74.
2007: Yang Hao; Sasaki Takashi; Minoshima Shinsei; Shimizu Nobuyoshi
Identification of three novel proteins (SGSM1, 2, 3) which modulate small G protein (RAP and RAB)-mediated signaling pathway.
Genomics 2007;90(2):249-60.
2007: Sasaki Takashi; Shimizu Nobuyoshi
Evolutionary conservation of a unique amino acid sequence in human DICER protein essential for binding to Argonaute family proteins.
Gene 2007;396(2):312-20.
2007: Su Feng; Osada Yumi; Ekker Marc; Chevrette Mario; Shimizu Atsushi; Asakawa Shuichi; Shiohama Aiko; Sasaki Takashi; Shimizu Nobuyoshi; Yamanaka Toshiyuki; Sasado Takao; Mitani Hiroshi; Geisler Robert; Kondoh Hisato; Furutani-Seiki Makoto
Radiation hybrid maps of Medaka chromosomes LG 12, 17, and 22.
DNA research : an international journal for rapid publication of reports on genes and genomes 2007;14(3):135-40.
2007: Morinaga Chikako; Saito Daisuke; Nakamura Shuhei; Sasaki Takashi; Asakawa Shuichi; Shimizu Nobuyoshi; Mitani Hiroshi; Furutani-Seiki Makoto; Tanaka Minoru; Kondoh Hisato
The hotei mutation of medaka in the anti-Mullerian hormone receptor causes the dysregulation of germ cell and sexual development.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9691-6.
2007: Imai Shuichiro; Sasaki Takashi; Shimizu Atsushi; Asakawa Shuichi; Hori Hiroshi; Shimizu Nobuyoshi
The genome size evolution of medaka (Oryzias latipes) and fugu (Takifugu rubripes).
Genes & genetic systems 2007;82(2):135-44.
2007: Maegawa Mari; Takeuchi Kenji; Funakoshi Eishi; Kawasaki Katsumi; Nishio Kazuto; Shimizu Nobuyoshi; Ito Fumiaki
Growth stimulation of non-small cell lung cancer cell lines by antibody against epidermal growth factor receptor promoting formation of ErbB2/ErbB3 heterodimers.
Molecular cancer research : MCR 2007;5(4):393-401.
2007: Yokoi Hayato; Shimada Atsuko; Carl Matthias; Takashima Shigeo; Kobayashi Daisuke; Narita Takanori; Jindo Tomoko; Kimura Tetsuaki; Kitagawa Tadao; Kage Takahiro; Sawada Atsushi; Naruse Kiyoshi; Asakawa Shuichi; Shimizu Nobuyoshi; Mitani Hiroshi; Shima Akihiro; Tsutsumi Makiko; Hori Hiroshi; Wittbrodt Joachim; Saga Yumiko; Ishikawa Yuji; Araki Kazuo; Takeda Hiroyuki
Mutant analyses reveal different functions of fgfr1 in medaka and zebrafish despite conserved ligand-receptor relationships.
Developmental biology 2007;304(1):326-37.
2007: Liang Chun-Shi; Kobiyama Atsushi; Shimizu Atsushi; Sasaki Takashi; Asakawa Shuichi; Shimizu Nobuyoshi; Watabe Shugo
Fast skeletal muscle myosin heavy chain gene cluster of medaka Oryzias latipes enrolled in temperature adaptation.
Physiological genomics 2007;29(2):201-14.
2007: Kato Mikio; Haku Takeshi; Hibino Takeshi; Fukada Harumi; Mishima Yumiko; Yamashita Ichiro; Minoshima Shinsei; Nagayama Kuniaki; Shimizu Nobuyoshi
Stable minihairpin structures forming at minisatellite DNA isolated from yellow fin sea bream Acanthopagrus latus.
Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology 2007;146(3):427-37.
2007: Shimizu Nobuyoshi; Ohtsubo Masafumi; Minoshima Shinsei
MutationView/KMcancerDB: a database for cancer gene mutations.
Cancer science 2007;98(3):259-67.
2007: Shinojima Toshiaki; Oya Mototsugu; Takayanagi Atsushi; Mizuno Ryuichi; Shimizu Nobuyoshi; Murai Masaru
Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha.
Carcinogenesis 2007;28(3):529-36.
2007: Sasaki Takashi; Shimizu Atsushi; Ishikawa Sabine K; Imai Shuichiro; Asakawa Shuichi; Murayama Yuji; Khorasani Maryam Zadeh; Mitani Hiroshi; Furutani-Seiki Makoto; Kondoh Hisato; Nanda Indrajit; Schmid Michael; Schartl Manfred; Nonaka Masaru; Takeda Hiroyuki; Hori Hiroshi; Himmelbauer Heinz; Shima Akihiro; Shimizu Nobuyoshi
The DNA sequence of medaka chromosome LG22.
Genomics 2007;89(1):124-33.
2007: Kato Mikio; Haku Takeshi; Yamauchi Takeshi; Sugiyama Shigeru; Nagayama Kuniaki; Shimizu Nobuyoshi
Structural characterization of supercoiled DNA containing a minisatellite repeat that has polypurine/polypyrimidine stretch.
Nucleic acids symposium series (2004) 2007;(51):341-2.
2007: Kawano Toshio; Wang Chunxia; Hotta Yoshihiro; Sato Miho; Iwata-Amano Emi; Hikoya Akiko; Fujita Naoya; Koyama Norihisa; Shirai Shoichiro; Azuma Noriyuki; Ohtsubo Masafumi; Shimizu Nobuyoshi; Minoshima Shinsei
Three novel mutations of the PAX6 gene in Japanese aniridia patients.
Journal of human genetics 2007;52(7):571-4.
2006: Funakoshi Eishi; Fukui Masaki; Hamano Ayako; Okamoto Hiroshi; Sugiyama Chie; Nishiyama Norito; Ogita Kiyokazu; Hori Takamitsu; Shimizu Nobuyoshi; Ito Fumiaki
Expression of m-Golsyn/Syntabulin gene during mouse brain development.
Neuroscience letters 2006;403(3):244-9.
2006: Kondo Mariko; Hornung Ute; Nanda Indrajit; Imai Shuichiro; Sasaki Takashi; Shimizu Atsushi; Asakawa Shuichi; Hori Hiroshi; Schmid Michael; Shimizu Nobuyoshi; Schartl Manfred
Genomic organization of the sex-determining and adjacent regions of the sex chromosomes of medaka.
Genome research 2006;16(7):815-26.
2006: Kurosawa Gene; Takamatsu Naofumi; Takahashi Masayoshi; Sumitomo Mariko; Sanaka Emi; Yamada Kouji; Nishii Kazuhiro; Matsuda Masaru; Asakawa Shuichi; Ishiguro Hiroshi; Miura Keiji; Kurosawa Yoshikazu; Shimizu Nobuyoshi; Kohara Yuji; Hori Hiroshi
Organization and structure of hox gene loci in medaka genome and comparison with those of pufferfish and zebrafish genomes.
Gene 2006;370():75-82.
2006: Mitani H; Kamei Y; Fukamachi S; Oda S; Sasaki T; Asakawa S; Todo T; Shimizu N
The medaka genome: why we need multiple fish models in vertebrate functional genomics.
Genome dynamics 2006;2():165-82.
2006: Funakoshi Eishi; Hamano Ayako; Fukui Masaki; Nishiyama Norito; Ogita Kiyokazu; Shimizu Nobuyoshi; Ito Fumiaki
Molecular cloning of the m-Golsyn gene and its expression in the mouse brain.
Gene expression 2006;13(1):27-40.
2005: Okui Michiyo; Yamaki Akiko; Takayanagi Atsushi; Kudoh Jun; Shimizu Nobuyoshi; Shimizu Yoshiko
Transcription factor single-minded 2 (SIM2) is ubiquitinated by the RING-IBR-RING-type E3 ubiquitin ligases.
Experimental cell research 2005;309(1):220-8.
2005: Takase Osamu; Marumo Takeshi; Imai Naohiko; Hirahashi Junichi; Takayanagi Atsushi; Hishikawa Keiichi; Hayashi Matsuhiko; Shimizu Nobuyoshi; Fujita Toshiro; Saruta Takao
NF-kappaB-dependent increase in intrarenal angiotensin II induced by proteinuria.
Kidney international 2005;68(2):464-73.
2005: Tsukamoto Kentaro; Hayashi Shinpei; Matsuo Megumi Y; Nonaka Mayumi I; Kondo Mariko; Shima Akihiro; Asakawa Shiuchi; Shimizu Nobuyoshi; Nonaka Masaru
Unprecedented intraspecific diversity of the MHC class I region of a teleost medaka, Oryzias latipes.
Immunogenetics 2005;57(6):420-31.
2005: Shibuya Kazunori; Kudoh Jun; Okui Michiyo; Shimizu Nobuyoshi
Identification of a novel zinc finger protein gene (ZNF298) in the GAP2 of human chromosome 21q.
Biochemical and biophysical research communications 2005;332(2):557-68.
2005: Henrich Thorsten; Ramialison Mirana; Wittbrodt Beate; Assouline Beatrice; Bourrat Franck; Berger Anja; Himmelbauer Heinz; Sasaki Takashi; Shimizu Nobuyoshi; Westerfield Monte; Kondoh Hisato; Wittbrodt Joachim
MEPD: a resource for medaka gene expression patterns.
Bioinformatics (Oxford, England) 2005;21(14):3195-7.
2005: Elmesiry Gamal E; Okai Sayaka; Hokabe Shingo; Minoshima Shinsei; Sugiyama Shigeru; Yoshino Tomoyuki; Ohtani Toshio; Shimizu Nobuyoshi; Kato Mikio
Isolation and characterization of simple repeat sequences from the yellow fin sea bream Acanthopagrus latus (Sparidae).
Molecular biology reports 2005;32(2):117-26.
2005: Machida Yutaka; Chiba Tomoki; Takayanagi Atsushi; Tanaka Yoshikazu; Asanuma Masato; Ogawa Norio; Koyama Akihiko; Iwatsubo Takeshi; Ito Shosuke; Jansen Poul Hening; Shimizu Nobuyoshi; Tanaka Keiji; Mizuno Yoshikuni; Hattori Nobutaka
Common anti-apoptotic roles of parkin and alpha-synuclein in human dopaminergic cells.
Biochemical and biophysical research communications 2005;332(1):233-40.
2005: Nakaniwa Makiko; Hirayama Makoto; Shimizu Atsushi; Sasaki Takashi; Asakawa Shuichi; Shimizu Nobuyoshi; Watabe Shugo
Genomic sequences encoding two types of medaka hemopexin-like protein Wap65, and their gene expression profiles in embryos.
The Journal of experimental biology 2005;208(Pt 10):1915-25.
2005: Uemura Takuji; Kudoh Jun; Noda Setsuko; Kanba Shigenobu; Shimizu Nobuyoshi
Characterization of human and mouse TRPM2 genes: identification of a novel N-terminal truncated protein specifically expressed in human striatum.
Biochemical and biophysical research communications 2005;328(4):1232-43.
2005: Wang Jun; Kudoh Jun; Takayanagi Atsushi; Shimizu Nobuyoshi
Novel human BTB/POZ domain-containing zinc finger protein ZNF295 is directly associated with ZFP161.
Biochemical and biophysical research communications 2005;327(2):615-27.
2005: Funakoshi Eishi; Nakagawa Kin-Ya; Hamano Ayako; Hori Takamitsu; Shimizu Atsushi; Asakawa Shuichi; Shimizu Nobuyoshi; Ito Fumiaki
Molecular cloning and characterization of gene for Golgi-localized syntaphilin-related protein on human chromosome 8q23.
Gene 2005;344():259-71.
2004: Funayama Tomoyo; Ishikawa Karin; Ohtake Yuichiro; Tanino Tomihiko; Kurosaka Daijiro; Kimura Itaru; Suzuki Kotaro; Ideta Hidenao; Nakamoto Kenji; Yasuda Noriko; Fujimaki Takuro; Murakami Akira; Asaoka Ryo; Hotta Yoshihiro; Tanihara Hidenobu; Kanamoto Takashi; Mishima Hiromu; Fukuchi Takeo; Abe Haruki; Iwata Takeshi; Shimada Naoki; Kudoh Jun; Shimizu Nobuyoshi; Mashima Yukihiko
Variants in optineurin gene and their association with tumor necrosis factor-alpha polymorphisms in Japanese patients with glaucoma.
Investigative ophthalmology & visual science 2004;45(12):4359-67.
2004: Fukamachi Shoji; Asakawa Shuichi; Wakamatsu Yuko; Shimizu Nobuyoshi; Mitani Hiroshi; Shima Akihiro
Conserved function of medaka pink-eyed dilution in melanin synthesis and its divergent transcriptional regulation in gonads among vertebrates.
Genetics 2004;168(3):1519-27.
2004: Tada Motoki N; Senzaki Kouji; Tai Yuumi; Morishita Hirofumi; Tanaka Yusuke Z; Murata Yoji; Ishii Yasuyuki; Asakawa Shuichi; Shimizu Nobuyoshi; Sugino Hidehiko; Yagi Takeshi
Genomic organization and transcripts of the zebrafish Protocadherin genes.
Gene 2004;340(2):197-211.
2004: Hosono Katsuhiro; Sasaki Takashi; Minoshima Shinsei; Shimizu Nobuyoshi
Identification and characterization of a novel gene family YPEL in a wide spectrum of eukaryotic species.
Gene 2004;340(1):31-43.
2004: Hatano Yasuko; Li Yuanzhe; Sato Kenichi; Asakawa Shuichi; Yamamura Yasuhiro; Tomiyama Hiroyuki; Yoshino Hiroyo; Asahina Masato; Kobayashi Susumu; Hassin-Baer Sharon; Lu Chin-Song; Ng Arlene R; Rosales Raymond L; Shimizu Nobuyoshi; Toda Tatsushi; Mizuno Yoshikuni; Hattori Nobutaka
Novel PINK1 mutations in early-onset parkinsonism.
Annals of neurology 2004;56(3):424-7.
2004: Akiyoshi Hiroko; Hatakeyama Shigetsugu; Pitkänen Jukka; Mouri Yasuhiro; Doucas Vassilis; Kudoh Jun; Tsurugaya Kyoko; Uchida Daisuke; Matsushima Akemi; Oshikawa Kiyotaka; Nakayama Keiichi I; Shimizu Nobuyoshi; Peterson Pärt; Matsumoto Mitsuru
Subcellular expression of autoimmune regulator is organized in a spatiotemporal manner.
The Journal of biological chemistry 2004;279(32):33984-91.
2004: Saga Masamichi; Mashima Yukihiko; Kudoh Jun; Oguchi Yoshihisa; Shimizu Nobuyoshi
Gene analysis and evaluation of the single founder effect in Japanese patients with Oguchi disease.
Japanese journal of ophthalmology 2004;48(4):350-2.
2004: Khorasani Maryam Zadeh; Hennig Steffen; Imre Gabriele; Asakawa Shuichi; Palczewski Stefanie; Berger Anja; Hori Hiroshi; Naruse Kiyoshi; Mitani Hiroshi; Shima Akihiro; Lehrach Hans; Wittbrodt Jochen; Kondoh Hisato; Shimizu Nobuyoshi; Himmelbauer Heinz
A first generation physical map of the medaka genome in BACs essential for positional cloning and clone-by-clone based genomic sequencing.
Mechanisms of development 2004;121(7-8):903-13.
2004: Naruse Kiyoshi; Hori Hiroshi; Shimizu Nobuyoshi; Kohara Yuji; Takeda Hiroyuki
Medaka genomics: a bridge between mutant phenotype and gene function.
Mechanisms of development 2004;121(7-8):619-28.
2004: Shibuya Kazunori; Nagamine Kentaro; Okui Michiyo; Ohsawa Yosuke; Asakawa Shuichi; Minoshima Shinsei; Hase Tetsu; Kudoh Jun; Shimizu Nobuyoshi
Initial characterization of an uromodulin-like 1 gene on human chromosome 21q22.3.
Biochemical and biophysical research communications 2004;319(4):1181-9.
2004: Yahagi Shoichi; Shibuya Kazunori; Obayashi Izumi; Masaki Hitoshi; Kurata Yoshiko; Kudoh Jun; Shimizu Nobuyoshi
Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11.
Biochemical and biophysical research communications 2004;318(3):655-64.
2004: Suzuki Masataka; Takayanagi Atsushi; Shimizu Nobuyoshi
Targeted gene delivery using humanized single-chain antibody with negatively charged oligopeptide tail.
Cancer science 2004;95(5):424-9.
2004: Maruyama Shinichiro; Misumi Osami; Ishii Yasuyuki; Asakawa Shuichi; Shimizu Atsushi; Sasaki Takashi; Matsuzaki Motomichi; Shin-i Tadasu; Nozaki Hisayoshi; Kohara Yuji; Shimizu Nobuyoshi; Kuroiwa Tsuneyoshi
The minimal eukaryotic ribosomal DNA units in the primitive red alga Cyanidioschyzon merolae.
DNA research : an international journal for rapid publication of reports on genes and genomes 2004;11(2):83-91.
2004: Toramoto Takuya; Ikeda Daisuke; Ochiai Yoshihiro; Minoshima Shinsei; Shimizu Nobuyoshi; Watabe Shugo
Multiple gene organization of pufferfish Fugu rubripes tropomyosin isoforms and tissue distribution of their transcripts.
Gene 2004;331():41-51.
2004: Shibuya Kazunori; Obayashi Izumi; Asakawa Shuichi; Minoshima Shinsei; Kudoh Jun; Shimizu Nobuyoshi
A cluster of 21 keratin-associated protein genes within introns of another gene on human chromosome 21q22.3.
Genomics 2004;83(4):679-93.
2004: Sugino Hidehiko; Yanase Hiroshi; Hamada Shun; Kurokawa Ken; Asakawa Shuichi; Shimizu Nobuyoshi; Yagi Takeshi
Distinct genomic sequence of the CNR/Pcdhalpha genes in chicken.
Biochemical and biophysical research communications 2004;316(2):437-45.
2004: Mashima Yukihiko; Nagano Makoto; Funayama Tomoyo; Zhang Qiang; Egashira Tohru; Kudho Jun; Shimizu Nobuyoshi; Oguchi Yoshihisa
Rapid quantification of the heteroplasmy of mutant mitochondrial DNAs in Leber's hereditary optic neuropathy using the Invader technology.
Clinical biochemistry 2004;37(4):268-76.
2004: Shibuya Kazunori; Kudoh Jun; Obayashi Izumi; Shimizu Atsushi; Sasaki Takashi; Minoshima Shinsei; Shimizu Nobuyoshi
Comparative genomics of the keratin-associated protein (KAP) gene clusters in human, chimpanzee, and baboon.
Mammalian genome : official journal of the International Mammalian Genome Society 2004;15(3):179-92.
2004: Ishii Yasuyuki; Asakawa Shuichi; Taguchi Yusuke; Ishibashi Shoko; Yagi Takeshi; Shimizu Nobuyoshi
Construction of BAC library for the amphibian Xenopus tropicalis.
Genes & genetic systems 2004;79(1):49-51.
2004: Watabe Masahiko; Hishikawa Keiichi; Takayanagi Atsushi; Shimizu Nobuyoshi; Nakaki Toshio
Caffeic acid phenethyl ester induces apoptosis by inhibition of NFkappaB and activation of Fas in human breast cancer MCF-7 cells.
The Journal of biological chemistry 2004;279(7):6017-26.
2004: Uchida Daisuke; Hatakeyama Shigetsugu; Matsushima Akemi; Han Hongwei; Ishido Satoshi; Hotta Hak; Kudoh Jun; Shimizu Nobuyoshi; Doucas Vassilis; Nakayama Keiichi I; Kuroda Noriyuki; Matsumoto Mitsuru
AIRE functions as an E3 ubiquitin ligase.
The Journal of experimental medicine 2004;199(2):167-72.
2004: Yamaki Akiko; Kudoh Jun; Shimizu Nobuyoshi; Shimizu Yoshiko
A novel nuclear localization signal in the human single-minded proteins SIM1 and SIM2.
Biochemical and biophysical research communications 2004;313(3):482-8.
2004: Kato Mikio; Hokabe Shingo; Haku Takeshi; Minoshima Shinsei; Nagayama Kuniaki; Shimizu Nobuyoshi
Single-stranded DNA structure of a minisatellite sequence isolated from Acanthopagrus latus.
Nucleic acids symposium series (2004) 2004;(48):153-4.
2004: Schartl Manfred; Nanda Indrajit; Kondo Mariko; Schmid Michael; Asakawa Shuichi; Sasaki Takashi; Shimizu Nobuyoshi; Henrich Thorsten; Wittbrodt Joachim; Furutani-Seiki Makoto; Kondoh Hisato; Himmelbauer Heinz; Hong Yunhan; Koga Akihiko; Nonaka Masaru; Mitani Hiroshi; Shima Akihiro
Current status of medaka genetics and genomics. The Medaka Genome Initiative (MGI).
Methods in cell biology 2004;77():173-99.
2003: Yagi Hisato; Furutani Yoshiyuki; Hamada Hiromichi; Sasaki Takashi; Asakawa Shuichi; Minoshima Shinsei; Ichida Fukiko; Joo Kunitaka; Kimura Misa; Imamura Shin-ichiro; Kamatani Naoyuki; Momma Kazuo; Takao Atsuyoshi; Nakazawa Makoto; Shimizu Nobuyoshi; Matsuoka Rumiko
Role of TBX1 in human del22q11.2 syndrome.
Lancet 2003;362(9393):1366-73.
2003: Yao Yuko; Yamamoto Takehiro; Tsutsumi Makiko; Matsuda Masaru; Hori Hiroshi; Naruse Kiyoshi; Mitani Hiroshi; Shima Akihiro; Asakawa Shuichi; Shimizu Nobuyoshi; Suzuki Norio
Genomic structure and expression of the soluble guanylyl cyclase alpha2 subunit gene in the medaka fish Oryzias latipes.
Zoological science 2003;20(10):1293-304.
2003: Okubo Kataaki; Ishii Shingo; Ishida Jun; Mitani Hiroshi; Naruse Kiyoshi; Kondo Mariko; Shima Akihiro; Tanaka Minoru; Asakawa Shuichi; Shimizu Nobuyoshi; Aida Katsumi
A novel third gonadotropin-releasing hormone receptor in the medaka Oryzias latipes: evolutionary and functional implications.
Gene 2003;314():121-31.
2003: Funakoshi Eishi; Hori Takamitsu; Haraguchi Tokuko; Hiraoka Yasushi; Kudoh Jun; Shimizu Nobuyoshi; Ito Fumiaki
Overexpression of the human MNB/DYRK1A gene induces formation of multinucleate cells through overduplication of the centrosome.
BMC cell biology 2003;4():12.
2003: Shimizu Atsushi; Asakawa Shuichi; Sasaki Takashi; Yamazaki Satoru; Yamagata Hidehisa; Kudoh Jun; Minoshima Shinsei; Kondo Ikuko; Shimizu Nobuyoshi
A novel giant gene CSMD3 encoding a protein with CUB and sushi multiple domains: a candidate gene for benign adult familial myoclonic epilepsy on human chromosome 8q23.3-q24.1.
Biochemical and biophysical research communications 2003;309(1):143-54.
2003: Sasaki Takashi; Shiohama Aiko; Minoshima Shinsei; Shimizu Nobuyoshi
Identification of eight members of the Argonaute family in the human genome small star, filled.
Genomics 2003;82(3):323-30.
2003: Spiteri Elizabeth; Babcock Melanie; Kashork Catherine D; Wakui Keiko; Gogineni Swarna; Lewis Debbie A; Williams Kisa M; Minoshima Shinsei; Sasaki Takashi; Shimizu Nobuyoshi; Potocki Lorraine; Pulijaal Venkat; Shanske Alan; Shaffer Lisa G; Morrow Bernice E
Frequent translocations occur between low copy repeats on chromosome 22q11.2 (LCR22s) and telomeric bands of partner chromosomes.
Human molecular genetics 2003;12(15):1823-37.
2003: Kato Mikio; Hokabe Shingo; Itakura Shuji; Minoshima Shinsei; Lyubchenko Yuri L; Gurkov Theodor D; Okawara Hiroshi; Nagayama Kuniaki; Shimizu Nobuyoshi
Interarm interaction of DNA cruciform forming at a short inverted repeat sequence.
Biophysical journal 2003;85(1):402-8.
2003: Ikeda Daisuke; Toramoto Takuya; Ochiai Yoshihiro; Suetake Hiroaki; Suzuki Yuzuru; Minoshima Shinsei; Shimizu Nobuyoshi; Watabe Shugo
Identification of novel tropomyosin 1 genes of pufferfish (Fugu rubripes) on genomic sequences and tissue distribution of their transcripts.
Molecular biology reports 2003;30(2):83-90.
2003: Yamasaki Kenshi; Toriu Nobuko; Hanakawa Yasushi; Shirakata Yuji; Sayama Koji; Takayanagi Atsushi; Ohtsubo Masafumi; Gamou Shinobu; Shimizu Nobuyoshi; Fujii Makiko; Miyazono Kohei; Hashimoto Koji
Keratinocyte growth inhibition by high-dose epidermal growth factor is mediated by transforming growth factor beta autoinduction: a negative feedback mechanism for keratinocyte growth.
The Journal of investigative dermatology 2003;120(6):1030-7.
2003: Ohtsubo Masafumi; Shibuya Kazunori; Kudoh Jun; Minoshima Shinsei; Shimizu Nobuyoshi
[Integrated database for mutations in disease genes: MutationView/KMDB]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2003;48(6):762-9.
2003: Suzuki M; Takayanagi A; Shimizu N
Recombinant single-chain antibodies with various oligopeptide tails for targeted gene delivery.
Gene therapy 2003;10(9):781-8.
2003: Ohtsubo Masafumi; Shimizu Nobuyoshi; Minoshima Shinsei
[The integrated database for mutations in disease-causing genes: Mutation View/KMDB]
Seikagaku. The Journal of Japanese Biochemical Society 2003;75(4):311-8.
2003: Shiohama Aiko; Sasaki Takashi; Noda Setsuko; Minoshima Shinsei; Shimizu Nobuyoshi
Molecular cloning and expression analysis of a novel gene DGCR8 located in the DiGeorge syndrome chromosomal region.
Biochemical and biophysical research communications 2003;304(1):184-90.
2003: Oya Mototsugu; Takayanagi Atsushi; Horiguchi Akio; Mizuno Ryuichi; Ohtsubo Masafumi; Marumo Ken; Shimizu Nobuyoshi; Murai Masaru
Increased nuclear factor-kappa B activation is related to the tumor development of renal cell carcinoma.
Carcinogenesis 2003;24(3):377-84.
2003: Kondo Mariko; Nanda Indrajit; Hornung Ute; Asakawa Shuichi; Shimizu Nobuyoshi; Mitani Hiroshi; Schmid Michael; Shima Akihiro; Schartl Manfred
Absence of the candidate male sex-determining gene dmrt1b(Y) of medaka from other fish species.
Current biology : CB 2003;13(5):416-20.
2003: Takase Osamu; Hirahashi Junichi; Takayanagi Atsushi; Chikaraishi Akihiro; Marumo Takeshi; Ozawa Yuri; Hayashi Matsuhiko; Shimizu Nobuyoshi; Saruta Takao
Gene transfer of truncated IkappaBalpha prevents tubulointerstitial injury.
Kidney international 2003;63(2):501-13.
2002: Harada Hirohisa; Wakabayashi Go; Takayanagi Atsushi; Shimazu Motohide; Matsumoto Kenji; Obara Hideaki; Shimizu Nobuyoshi; Kitajima Masaki
Transfer of the interleukin-1 receptor antagonist gene into rat liver abrogates hepatic ischemia-reperfusion injury.
Transplantation 2002;74(10):1434-41.
2002: Guipponi Michel; Vuagniaux Grégoire; Wattenhofer Marie; Shibuya Kazunori; Vazquez Maria; Dougherty Loretta; Scamuffa Nathalie; Guida Elizabeth; Okui Michiyo; Rossier Colette; Hancock Manuela; Buchet Karine; Reymond Alexandre; Hummler Edith; Marzella Phillip L; Kudoh Jun; Shimizu Nobuyoshi; Scott Hamish S; Antonarakis Stylianos E; Rossier Bernard C
The transmembrane serine protease (TMPRSS3) mutated in deafness DFNB8/10 activates the epithelial sodium channel (ENaC) in vitro.
Human molecular genetics 2002;11(23):2829-36.
2002: Nanda Indrajit; Kondo Mariko; Hornung Ute; Asakawa Shuichi; Winkler Christoph; Shimizu Atsushi; Shan Zhihong; Haaf Thomas; Shimizu Nobuyoshi; Shima Akihiro; Schmid Michael; Schartl Manfred
A duplicated copy of DMRT1 in the sex-determining region of the Y chromosome of the medaka, Oryzias latipes.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11778-83.
2002: Froschauer Alexander; Körting Cornelia; Katagiri Takayuki; Aoki Takashi; Asakawa Shuichi; Shimizu Nobuyoshi; Schartl Manfred; Volff Jean-Nicolas
Construction and initial analysis of bacterial artificial chromosome (BAC) contigs from the sex-determining region of the platyfish Xiphophorus maculatus.
Gene 2002;295(2):247-54.
2002: Kondo Mariko; Froschauer Alexander; Kitano Akiko; Nanda Indrajit; Hornung Ute; Volff Jean-Nicolas; Asakawa Shuichi; Mitani Hiroshi; Naruse Kiyoshi; Tanaka Minoru; Schmid Michael; Shimizu Nobuyoshi; Schartl Manfred; Shima Akihiro
Molecular cloning and characterization of DMRT genes from the medaka Oryzias latipes and the platyfish Xiphophorus maculatus.
Gene 2002;295(2):213-22.
2002: Kato Mikio; McAllister Chad J; Hokabe Shingo; Shimizu Nobuyoshi; Lyubchenko Yuri L
Structural heterogeneity of pyrimidine/purine-biased DNA sequence analyzed by atomic force microscopy.
European journal of biochemistry / FEBS 2002;269(15):3632-6.
2002: Okubo Kataaki; Mitani Hiroshi; Naruse Kiyoshi; Kondo Mariko; Shima Akihiro; Tanaka Minoru; Asakawa Shuichi; Shimizu Nobuyoshi; Yoshiura Yasutoshi; Aida Katsumi
Structural characterization of GnRH loci in the medaka genome.
Gene 2002;293(1-2):181-9.
2002: Yoshihama Maki; Uechi Tamayo; Asakawa Shuichi; Kawasaki Kazuhiko; Kato Seishi; Higa Sayomi; Maeda Noriko; Minoshima Shinsei; Tanaka Tatsuo; Shimizu Nobuyoshi; Kenmochi Naoya
The human ribosomal protein genes: sequencing and comparative analysis of 73 genes.
Genome research 2002;12(3):379-90.
2002: Matsuo Megumi Y; Asakawa Shuichi; Shimizu Nobuyoshi; Kimura Hiroshi; Nonaka Masaru
Nucleotide sequence of the MHC class I genomic region of a teleost, the medaka (Oryzias latipes).
Immunogenetics 2002;53(10-11):930-40.
2002: Shimizu Nobuyoshi
[Drug discovery based on the human genome sciences]
Gan to kagaku ryoho. Cancer & chemotherapy 2002;29(1):1-6.
2002: Hokabe Shingo; Gurkov Theodor D; Okawara Hiroshi; Nagayama Kuniaki; Minoshima Shinsei; Shimizu Nobuyoshi; Kato Mikio
Chemical probing and electron microscopic analysis of alternative DNA structure formed in an inverted repeat sequence.
Nucleic acids research. Supplement (2001) 2002;(2):217-8.
2001: Sasaki T; Minoshima S; Shiohama A; Shintani A; Shimizu A; Asakawa S; Kawasaki K; Shimizu N
Molecular cloning of a member of the facilitative glucose transporter gene family GLUT11 (SLC2A11) and identification of transcription variants.
Biochemical and biophysical research communications 2001;289(5):1218-24.
2001: Asakawa S; Tsunematsu Ki; Takayanagi A; Sasaki T; Shimizu A; Shintani A; Kawasaki K; Mungall A J; Beck S; Minoshima S; Shimizu N
The genomic structure and promoter region of the human parkin gene.
Biochemical and biophysical research communications 2001;286(5):863-8.
2001: Heino M; Peterson P; Kudoh J; Shimizu N; Antonarakis S E; Scott H S; Krohn K
APECED mutations in the autoimmune regulator (AIRE) gene.
Human mutation 2001;18(3):205-11.
2001: Kondo S; Kuwahara Y; Kondo M; Naruse K; Mitani H; Wakamatsu Y; Ozato K; Asakawa S; Shimizu N; Shima A
The medaka rs-3 locus required for scale development encodes ectodysplasin-A receptor.
Current biology : CB 2001;11(15):1202-6.
2001: Shimizu N; Ochi T; Itonaga K
Replication timing of amplified genetic regions relates to intranuclear localization but not to genetic activity or G/R band.
Experimental cell research 2001;268(2):201-10.
2001: Kubo S I; Kitami T; Noda S; Shimura H; Uchiyama Y; Asakawa S; Minoshima S; Shimizu N; Mizuno Y; Hattori N
Parkin is associated with cellular vesicles.
Journal of neurochemistry 2001;78(1):42-54.
2001: Oya M; Ohtsubo M; Takayanagi A; Tachibana M; Shimizu N; Murai M
Constitutive activation of nuclear factor-kappaB prevents TRAIL-induced apoptosis in renal cancer cells.
Oncogene 2001;20(29):3888-96.
2001: Wang M; Suzuki T; Kitada T; Asakawa S; Minoshima S; Shimizu N; Tanaka K; Mizuno Y; Hattori N
Developmental changes in the expression of parkin and UbcR7, a parkin-interacting and ubiquitin-conjugating enzyme, in rat brain.
Journal of neurochemistry 2001;77(6):1561-8.
2001: Yamaki A; Tochigi J; Kudoh J; Minoshima S; Shimizu N; Shimizu Y
Molecular mechanisms of human single-minded 2 (SIM2) gene expression: identification of a promoter site in the SIM2 genomic sequence.
Gene 2001;270(1-2):265-75.
2001: Kawasaki K; Minoshima S; Nakato E; Shibuya K; Shintani A; Asakawa S; Sasaki T; Klobeck H G; Combriato G; Zachau H G; Shimizu N
Evolutionary dynamics of the human immunoglobulin kappa locus and the germline repertoire of the Vkappa genes.
European journal of immunology 2001;31(4):1017-28.
2001: Obata K; Fukuda T; Morishita R; Abe S; Asakawa S; Yamaguchi S; Yoshino M; Ihara K; Murayama K; Shigemoto K; Shimizu N; Kondo I
Human biotin-containing subunit of 3-methylcrotonyl-CoA carboxylase gene (MCCA): cDNA sequence, genomic organization, localization to chromosomal band 3q27, and expression.
Genomics 2001;72(2):145-52.
2001: Wattenhofer M; Shibuya K; Kudoh J; Lyle R; Michaud J; Rossier C; Kawasaki K; Asakawa S; Minoshima S; Berry A; Bonne-Tamir B; Shimizu N; Antonarakis S E; Scott H S
Isolation and characterization of the UBASH3A gene on 21q22.3 encoding a potential nuclear protein with a novel combination of domains.
Human genetics 2001;108(2):140-7.
2001: Yamashita S; Takayanagi A; Shimizu N
Effects of neonatal diethylstilbestrol exposure on c-fos and c-jun protooncogene expression in the mouse uterus.
Histology and histopathology 2001;16(1):131-40.
2001: Scott H S; Kudoh J; Wattenhofer M; Shibuya K; Berry A; Chrast R; Guipponi M; Wang J; Kawasaki K; Asakawa S; Minoshima S; Younus F; Mehdi S Q; Radhakrishna U; Papasavvas M P; Gehrig C; Rossier C; Korostishevsky M; Gal A; Shimizu N; Bonne-Tamir B; Antonarakis S E
Insertion of beta-satellite repeats identifies a transmembrane protease causing both congenital and childhood onset autosomal recessive deafness.
Nature genetics 2001;27(1):59-63.
2001: Minoshima S; Mitsuyama S; Ohtsubo M; Kawamura T; Ito S; Shibamoto S; Ito F; Shimizu N
The KMDB/MutationView: a mutation database for human disease genes.
Nucleic acids research 2001;29(1):327-8.
2001: Kato M; Gurkov T D; Elmesiry G E; Shimizu N; Nagayama K
Electron microscopic imaging of supercoiled DNA containing highly biased sequence.
Nucleic acids research. Supplement (2001) 2001;(1):157-8.
2001: Takahashi T; Kawamura Y; Sakata N; Elmesiry G E; Takemon Y; Tanida K; Minoshima S; Shimizu N; Kato M
Nucleotide sequence of BamHI family satellite DNA and its unit length polymorphism in bluegill sunfish Lepomis macrochirus.
Molecular biology reports 2001;28(2):119-22.
2001: Mizuno Y; Hattori N; Kitada T; Matsumine H; Mori H; Shimura H; Kubo S; Kobayashi H; Asakawa S; Minoshima S; Shimizu N
Familial Parkinson's disease. Alpha-synuclein and parkin.
Advances in neurology 2001;86():13-21.
2000: Bartoloni L; Wattenhofer M; Kudoh J; Berry A; Shibuya K; Kawasaki K; Wang J; Asakawa S; Talior I; Bonne-Tamir B; Rossier C; Michaud J; McCabe E R; Minoshima S; Shimizu N; Scott H S; Antonarakis S E
Cloning and characterization of a putative human glycerol 3-phosphate permease gene (SLC37A1 or G3PP) on 21q22.3: mutation analysis in two candidate phenotypes, DFNB10 and a glycerol kinase deficiency.
Genomics 2000;70(2):190-200.
2000: Shimizu N
[Frontiers of the human genome project: complete sequencing of the chromosomes 22 and 21]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2000;45(14):2432-40.
2000: Obara H; Takayanagi A; Hirahashi J; Tanaka K; Wakabayashi G; Matsumoto K; Shimazu M; Shimizu N; Kitajima M
Overexpression of truncated IkappaBalpha induces TNF-alpha-dependent apoptosis in human vascular smooth muscle cells.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(10):2198-204.
2000: Hattori N; Shimura H; Kubo S; Kitada T; Wang M; Asakawa S; Minashima S; Shimizu N; Suzuki T; Tanaka K; Mizuno Y
Autosomal recessive juvenile parkinsonism: a key to understanding nigral degeneration in sporadic Parkinson's disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20 Suppl():S85-90.
2000: Mashima Y; Saga M; Hiida Y; Imamura Y; Kudoh J; Shimizu N
Novel mutation in RP2 gene in two brothers with X-linked retinitis pigmentosa and mtDNA mutation of leber hereditary optic neuropathy who showed marked differences in clinical severity.
American journal of ophthalmology 2000;130(3):357-9.
2000: Kubota R; Mashima Y; Ohtake Y; Tanino T; Kimura T; Hotta Y; Kanai A; Tokuoka S; Azuma I; Tanihara H; Inatani M; Inoue Y; Kudoh J; Oguchi Y; Shimizu N
Novel mutations in the myocilin gene in Japanese glaucoma patients.
Human mutation 2000;16(3):270.
2000: Michaud J; Kudoh J; Berry A; Bonne-Tamir B; Lalioti M D; Rossier C; Shibuya K; Kawasaki K; Asakawa S; Minoshima S; Shimizu N; Antonarakis S E; Scott H S
Isolation and characterization of a human chromosome 21q22.3 gene (WDR4) and its mouse homologue that code for a WD-repeat protein.
Genomics 2000;68(1):71-9.
2000: Guipponi M; Brunschwig K; Chamoun Z; Scott H S; Shibuya K; Kudoh J; Delezoide A L; El Samadi S; Chettouh Z; Rossier C; Shimizu N; Mueller F; Delabar J M; Antonarakis S E
C21orf5, a novel human chromosome 21 gene, has a Caenorhabditis elegans ortholog (pad-1) required for embryonic patterning.
Genomics 2000;68(1):30-40.
2000: Berry A; Scott H S; Kudoh J; Talior I; Korostishevsky M; Wattenhofer M; Guipponi M; Barras C; Rossier C; Shibuya K; Wang J; Kawasaki K; Asakawa S; Minoshima S; Shimizu N; Antonarakis S; Bonné-Tamir B
Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region.
Genomics 2000;68(1):22-9.
2000: Kawasaki K; Minoshima S; Shimizu N
Propagation and maintenance of the 119 human immunoglobulin Vlambda genes and pseudogenes during evolution.
The Journal of experimental zoology 2000;288(2):120-34.
2000: Heino M; Peterson P; Sillanpää N; Guérin S; Wu L; Anderson G; Scott H S; Antonarakis S E; Kudoh J; Shimizu N; Jenkinson E J; Naquet P; Krohn K J
RNA and protein expression of the murine autoimmune regulator gene (Aire) in normal, RelB-deficient and in NOD mouse.
European journal of immunology 2000;30(7):1884-93.
2000: Shimura H; Hattori N; Kubo S i; Mizuno Y; Asakawa S; Minoshima S; Shimizu N; Iwai K; Chiba T; Tanaka K; Suzuki T
Familial Parkinson disease gene product, parkin, is a ubiquitin-protein ligase.
Nature genetics 2000;25(3):302-5.
2000: Ohtsubo M; Takayanagi A; Gamou S; Shimizu N
Interruption of NFkappaB-STAT1 signaling mediates EGF-induced cell-cycle arrest.
Journal of cellular physiology 2000;184(1):131-7.
2000: Shimizu N; Minoshima S
[Computer databases on cancer-related genes]
Nippon rinsho. Japanese journal of clinical medicine 2000;58(6):1211-8.
2000: Kitada T; Asakawa S; Minoshima S; Mizuno Y; Shimizu N
Molecular cloning, gene expression, and identification of a splicing variant of the mouse parkin gene.
Mammalian genome : official journal of the International Mammalian Genome Society 2000;11(6):417-21.
2000: Pitkänen J; Doucas V; Sternsdorf T; Nakajima T; Aratani S; Jensen K; Will H; Vähämurto P; Ollila J; Vihinen M; Scott H S; Antonarakis S E; Kudoh J; Shimizu N; Krohn K; Peterson P
The autoimmune regulator protein has transcriptional transactivating properties and interacts with the common coactivator CREB-binding protein.
The Journal of biological chemistry 2000;275(22):16802-9.
2000: Aapola U; Kawasaki K; Scott H S; Ollila J; Vihinen M; Heino M; Shintani A; Kawasaki K; Minoshima S; Krohn K; Antonarakis S E; Shimizu N; Kudoh J; Peterson P
Isolation and initial characterization of a novel zinc finger gene, DNMT3L, on 21q22.3, related to the cytosine-5-methyltransferase 3 gene family.
Genomics 2000;65(3):293-8.
2000: Shibuya K; Kudoh J; Minoshima S; Kawasaki K; Asakawa S; Shimizu N
Isolation of two novel genes, DSCR5 and DSCR6, from Down syndrome critical region on human chromosome 21q22.2.
Biochemical and biophysical research communications 2000;271(3):693-8.
2000: Kitada T; Asakawa S; Matsumine H; Hattori N; Shimura H; Minoshima S; Shimizu N; Mizuno Y
Progress in the clinical and molecular genetics of familial parkinsonism.
Neurogenetics 2000;2(4):207-18.
2000: Shimizu N; Shimura T; Tanaka T
Selective elimination of acentric double minutes from cancer cells through the extrusion of micronuclei.
Mutation research 2000;448(1):81-90.
2000: Hirahashi J; Takayanagi A; Hishikawa K; Takase O; Chikaraishi A; Hayashi M; Shimizu N; Saruta T
Overexpression of truncated I kappa B alpha potentiates TNF-alpha-induced apoptosis in mesangial cells.
Kidney international 2000;57(3):959-68.
2000: Proby C M; Ota T; Suzuki H; Koyasu S; Gamou S; Shimizu N; Wahl J K; Wheelock M J; Nishikawa T; Amagai M
Development of chimeric molecules for recognition and targeting of antigen-specific B cells in pemphigus vulgaris.
The British journal of dermatology 2000;142(2):321-30.
2000: Tanaka T; Shimizu N
Induced detachment of acentric chromatin from mitotic chromosomes leads to their cytoplasmic localization at G(1) and the micronucleation by lamin reorganization at S phase.
Journal of cell science 2000;113 ( Pt 4)():697-707.
2000: Takahashi H; Noda S; Mashima Y; Kubota R; Ohtake Y; Tanino T; Kudoh J; Minoshima S; Oguchi Y; Shimizu N
The myocilin (MYOC) gene expression in the human trabecular meshwork.
Current eye research 2000;20(2):81-4.
2000: Minoshima S; Mitsuyama S; Ohno S; Kawamura T; Shimizu N
Keio Mutation Database (KMDB) for human disease gene mutations.
Nucleic acids research 2000;28(1):364-8.
2000: Okui M; Ito F; Ogita K; Kuramoto N; Kudoh J; Shimizu N; Ide T
Expression of APG-2 protein, a member of the heat shock protein 110 family, in developing rat brain.
Neurochemistry international 2000;36(1):35-43.
2000: Hattori N; Shimura H; Kubo S; Wang M; Shimizu N; Tanaka K; Mizuno Y
Importance of familial Parkinson's disease and parkinsonism to the understanding of nigral degeneration in sporadic Parkinson's disease.
Journal of neural transmission. Supplementum 2000;(60):101-16.
2000: Shimizu N; Asakawa S; Minoshima S; Kitada T; Hattori N; Matsumine H; Yokochi M; Yamamura Y; Mizuno Y
PARKIN as a pathogenic gene for autosomal recessive juvenile parkinsonism.
Journal of neural transmission. Supplementum 2000;(58):19-30.
2000: Minoshima S; Mitsuyama S; Ohno S; Kawamura T; Shimizu N
Eye disorder database "KMeyeDB".
Human mutation 2000;15(1):95-8.
1999: Kitada T; Asakawa S; Matsumine H; Hattori N; Minoshima S; Shimizu N; Mizuno Y
Positional cloning of the autosomal recessive juvenile parkinsonism (AR-JP) gene and its diversity in deletion mutations.
Parkinsonism & related disorders 1999;5(4):163-8.
1999: Okui M; Ide T; Morita K; Funakoshi E; Ito F; Ogita K; Yoneda Y; Kudoh J; Shimizu N
High-level expression of the Mnb/Dyrk1A gene in brain and heart during rat early development.
Genomics 1999;62(2):165-71.
1999: Kato M; Kato A; Shimizu N
A method for evaluating phylogenetic relationship of alpha-satellite DNA suprachromosomal family by nucleotide frequency calculation.
Molecular phylogenetics and evolution 1999;13(2):329-35.
1999: Nagasawa A; Kudoh J; Noda S; Mashima Y; Wright A; Oguchi Y; Shimizu N
Human and mouse ISLR (immunoglobulin superfamily containing leucine-rich repeat) genes: genomic structure and tissue expression.
Genomics 1999;61(1):37-43.
1999: Sumitomo M; Tachibana M; Murai M; Hayakawa M; Nakamura H; Takayanagi A; Shimizu N
Overexpression of IL-1ra gene up-regulates interleukin-1beta converting enzyme (ICE) gene expression: possible mechanism underlying IL-1beta-resistance of cancer cells.
British journal of cancer 1999;81(2):277-86.
1999: Shimizu N; Minoshima S; Asakawa S
[Cloning of Parkin gene and its function]
No to shinkei = Brain and nerve 1999;51(6):487-91.
1999: Shimura H; Hattori N; Kubo S; Yoshikawa M; Kitada T; Matsumine H; Asakawa S; Minoshima S; Yamamura Y; Shimizu N; Mizuno Y
Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients.
Annals of neurology 1999;45(5):668-72.
1999: Wang M; Hattori N; Matsumine H; Kobayashi T; Yoshino H; Morioka A; Kitada T; Asakawa S; Minoshima S; Shimizu N; Mizuno Y
Polymorphism in the parkin gene in sporadic Parkinson's disease.
Annals of neurology 1999;45(5):655-8.
1999: Ohtake Y; Chen J; Gamou S; Takayanagi A; Mashima Y; Oguchi Y; Shimizu N
Ex vivo delivery of suicide genes into melanoma cells using epidermal growth factor receptor-specific Fab immunogene.
Japanese journal of cancer research : Gann 1999;90(4):460-8.
1999: Heino M; Peterson P; Kudoh J; Nagamine K; Lagerstedt A; Ovod V; Ranki A; Rantala I; Nieminen M; Tuukkanen J; Scott H S; Antonarakis S E; Shimizu N; Krohn K
Autoimmune regulator is expressed in the cells regulating immune tolerance in thymus medulla.
Biochemical and biophysical research communications 1999;257(3):821-5.
1999: Mittaz L; Rossier C; Heino M; Peterson P; Krohn K J; Gos A; Morris M A; Kudoh J; Shimizu N; Antonarakis S E; Scott H S
Isolation and characterization of the mouse Aire gene.
Biochemical and biophysical research communications 1999;255(2):483-90.
1999: Sumitomo M; Tachibana M; Ozu C; Asakura H; Murai M; Hayakawa M; Nakamura H; Takayanagi A; Shimizu N
Induction of apoptosis of cytokine-producing bladder cancer cells by adenovirus-mediated IkappaBalpha overexpression.
Human gene therapy 1999;10(1):37-47.
1999: Mashima Y; Nakamura Y; Noda K; Konishi M; Yamada M; Kudoh J; Shimizu N
A novel mutation at codon 124 (R124L) in the BIGH3 gene is associated with a superficial variant of granular corneal dystrophy.
Archives of ophthalmology 1999;117(1):90-3.
1999: Minoshima S; Mitsuyama S; Ohno S; Kawamura T; Shimizu N
Keio Mutation Database for eye disease genes (KMeyeDB).
Nucleic acids research 1999;27(1):358-61.
1999: Mashima Y; Shinoda K; Ishida S; Ozawa Y; Kudoh J; Iwata T; Oguchi Y; Shimizu N
Identification of four novel mutations of the XLRS1 gene in Japanese patients with X-linked juvenile retinoschisis. Mutation in brief no. 234. Online.
Human mutation 1999;13(4):338.
1999: Heino M; Scott H S; Chen Q; Peterson P; Mäebpää U; Papasavvas M P; Mittaz L; Barras C; Rossier C; Chrousos G P; Stratakis C A; Nagamine K; Kudoh J; Shimizu N; Maclaren N; Antonarakis S E; Krohn K
Mutation analyses of North American APS-1 patients.
Human mutation 1999;13(1):69-74.
1998: Chen J; Gamou S; Takayanagi A; Ohtake Y; Ohtsubo M; Shimizu N
Targeted in vivo delivery of therapeutic gene into experimental squamous cell carcinomas using anti-epidermal growth factor receptor antibody: immunogene approach.
Human gene therapy 1998;9(18):2673-81.
1998: Hattori N; Kitada T; Matsumine H; Asakawa S; Yamamura Y; Yoshino H; Kobayashi T; Yokochi M; Wang M; Yoritaka A; Kondo T; Kuzuhara S; Nakamura S; Shimizu N; Mizuno Y
Molecular genetic analysis of a novel Parkin gene in Japanese families with autosomal recessive juvenile parkinsonism: evidence for variable homozygous deletions in the Parkin gene in affected individuals.
Annals of neurology 1998;44(6):935-41.
1998: Mashima Y; Konishi M; Nakamura Y; Imamura Y; Yamada M; Ogata T; Kudoh J; Shimizu N
Severe form of juvenile corneal stromal dystrophy with homozygous R124H mutation in the keratoepithelin gene in five Japanese patients.
The British journal of ophthalmology 1998;82(11):1280-4.
1998: Chen J; Gamou S; Takayanagi A; Ohtake Y; Ohtsubo M; Shimizu N
Receptor-mediated gene delivery using the Fab fragments of anti-epidermal growth factor receptor antibodies: improved immunogene approach.
Cancer gene therapy 1998;5(6):357-64.
1998: Nagamine K; Kudoh J; Minoshima S; Kawasaki K; Asakawa S; Ito F; Shimizu N
Molecular cloning of a novel putative Ca2+ channel protein (TRPC7) highly expressed in brain.
Genomics 1998;54(1):124-31.
1998: Itoh N; Shimizu N
DNA replication-dependent intranuclear relocation of double minute chromatin.
Journal of cell science 1998;111 ( Pt 22)():3275-85.
1998: Rosatelli M C; Meloni A; Meloni A; Devoto M; Cao A; Scott H S; Peterson P; Heino M; Krohn K J; Nagamine K; Kudoh J; Shimizu N; Antonarakis S E
A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients.
Human genetics 1998;103(4):428-34.
1998: Guipponi M; Scott H S; Kudoh J; Kawasaki K; Shibuya K; Shintani A; Asakawa S; Chen H; Lalioti M D; Rossier C; Minoshima S; Shimizu N; Antonarakis S E
Identification and characterization of a novel cyclic nucleotide phosphodiesterase gene (PDE9A) that maps to 21q22.3: alternative splicing of mRNA transcripts, genomic structure and sequence.
Human genetics 1998;103(4):386-92.
1998: Wang J; Kudoh J; Shintani A; Minoshima S; Shimizu N
Identification of two novel 5' noncoding exons in human MNB/DYRK gene and alternatively spliced transcripts.
Biochemical and biophysical research communications 1998;250(3):704-10.
1998: Peterson P; Nagamine K; Scott H; Heino M; Kudoh J; Shimizu N; Antonarakis S E; Krohn K J
APECED: a monogenic autoimmune disease providing new clues to self-tolerance.
Immunology today 1998;19(9):384-6.
1998: Konishi M; Mashima Y; Yamada M; Kudoh J; Shimizu N
The classic form of granular corneal dystrophy associated with R555W mutation in the BIGH3 gene is rare in Japanese patients.
American journal of ophthalmology 1998;126(3):450-2.
1998: Hattori N; Matsumine H; Asakawa S; Kitada T; Yoshino H; Elibol B; Brookes A J; Yamamura Y; Kobayashi T; Wang M; Yoritaka A; Minoshima S; Shimizu N; Mizuno Y
Point mutations (Thr240Arg and Gln311Stop) [correction of Thr240Arg and Ala311Stop] in the Parkin gene.
Biochemical and biophysical research communications 1998;249(3):754-8.
1998: Scott H S; Heino M; Peterson P; Mittaz L; Lalioti M D; Betterle C; Cohen A; Seri M; Lerone M; Romeo G; Collin P; Salo M; Metcalfe R; Weetman A; Papasavvas M P; Rossier C; Nagamine K; Kudoh J; Shimizu N; Krohn K J; Antonarakis S E
Common mutations in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients of different origins.
Molecular endocrinology (Baltimore, Md.) 1998;12(8):1112-9.
1998: Matsuoka R; Kimura M; Scambler P J; Morrow B E; Imamura S; Minoshima S; Shimizu N; Yamagishi H; Joh-o K; Watanabe S; Oyama K; Saji T; Ando M; Takao A; Momma K
Molecular and clinical study of 183 patients with conotruncal anomaly face syndrome.
Human genetics 1998;103(1):70-80.
1998: Imamura Y; Noda S; Mashima Y; Kudoh J; Oguchi Y; Shimizu N
Human retina-specific amine oxidase: genomic structure of the gene (AOC2), alternatively spliced variant, and mRNA expression in retina.
Genomics 1998;51(2):293-8.
1998: Takahashi H; Noda S; Imamura Y; Nagasawa A; Kubota R; Mashima Y; Kudoh J; Oguchi Y; Shimizu N
Mouse myocilin (Myoc) gene expression in ocular tissues.
Biochemical and biophysical research communications 1998;248(1):104-9.
1998: Nakamura H; Oda T; Hamada K; Hirano T; Shimizu N; Utiyama H
Survival by Mac-1-mediated adherence and anoikis in phorbol ester-treated HL-60 cells.
The Journal of biological chemistry 1998;273(25):15345-51.
1998: Kato M; Matsunaga K; Shimizu N
A novel unusual DNA structure formed in an inverted repeat sequence.
Biochemical and biophysical research communications 1998;246(2):532-4.
1998: Asakawa S; Shimizu N
High-fidelity digital hybridization screening.
Genomics 1998;49(2):209-17.
1998: Mashima Y; Yamada K; Wakakura M; Kigasawa K; Kudoh J; Shimizu N; Oguchi Y
Spectrum of pathogenic mitochondrial DNA mutations and clinical features in Japanese families with Leber's hereditary optic neuropathy.
Current eye research 1998;17(4):403-8.
1998: Kitada T; Asakawa S; Hattori N; Matsumine H; Yamamura Y; Minoshima S; Yokochi M; Mizuno Y; Shimizu N
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism.
Nature 1998;392(6676):605-8.
1998: Takayanagi A; Chen J; Gamou S; Shimizu N
[Targeting delivery of therapeutic genes using monoclonal antibody; immunogene approach]
Nippon rinsho. Japanese journal of clinical medicine 1998;56(3):731-6.
1998: Saga M; Mashima Y; Akeo K; Kudoh J; Oguchi Y; Shimizu N
A novel homozygous Ile535Asn mutation in the rod cGMP phosphodiesterase beta-subunit gene in two brothers of a Japanese family with autosomal recessive retinitis pigmentosa.
Current eye research 1998;17(3):332-5.
1998: Hamada K; Nakamura H; Oda T; Hirano T; Shimizu N; Utiyama H
Involvement of Mac-1-mediated adherence and sphingosine 1-phosphate in survival of phorbol ester-treated U937 cells.
Biochemical and biophysical research communications 1998;244(3):745-50.
1998: Shimizu N; Itoh N; Utiyama H; Wahl G M
Selective entrapment of extrachromosomally amplified DNA by nuclear budding and micronucleation during S phase.
The Journal of cell biology 1998;140(6):1307-20.
1998: Ohtsubo M; Gamou S; Shimizu N
Antisense oligonucleotide of WAF1 gene prevents EGF-induced cell-cycle arrest in A431 cells.
Oncogene 1998;16(6):797-802.
1998: Kubota R; Kudoh J; Mashima Y; Asakawa S; Minoshima S; Hejtmancik J F; Oguchi Y; Shimizu N
Genomic organization of the human myocilin gene (MYOC) responsible for primary open angle glaucoma (GLC1A).
Biochemical and biophysical research communications 1998;242(2):396-400.
1998: Nakayama T; Matsuoka R; Kimura M; Hirota H; Mikoshiba K; Shimizu Y; Shimizu N; Akagawa K
Hemizygous deletion of the HPC-1/syntaxin 1A gene (STX1A) in patients with Williams syndrome.
Cytogenetics and cell genetics 1998;82(1-2):49-51.
1997: Minoshima S; Shimizu N
[Genome information database]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(17 Suppl):3038-45.
1997: Shimizu N; Kudoh J; Minoshima S; Kawasaki K; Asakawa S
[Physical mapping of disease-associated regions and functional analysis of pathogenic genes: gene hunting by genomic DNA sequencing and cDNA screening]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1997;42(17 Suppl):2729-36.
1997: Nagamine K; Peterson P; Scott H S; Kudoh J; Minoshima S; Heino M; Krohn K J; Lalioti M D; Mullis P E; Antonarakis S E; Kawasaki K; Asakawa S; Ito F; Shimizu N
Positional cloning of the APECED gene.
Nature genetics 1997;17(4):393-8.
1997: Nagasawa A; Kubota R; Imamura Y; Nagamine K; Wang Y; Asakawa S; Kudoh J; Minoshima S; Mashima Y; Oguchi Y; Shimizu N
Cloning of the cDNA for a new member of the immunoglobulin superfamily (ISLR) containing leucine-rich repeat (LRR).
Genomics 1997;44(3):273-9.
1997: Ishii K; Amagai M; Hall R P; Hashimoto T; Takayanagi A; Gamou S; Shimizu N; Nishikawa T
Characterization of autoantibodies in pemphigus using antigen-specific enzyme-linked immunosorbent assays with baculovirus-expressed recombinant desmogleins.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):2010-7.
1997: Nagamine K; Kudoh J; Minoshima S; Kawasaki K; Asakawa S; Ito F; Shimizu N
Genomic organization and complete nucleotide sequence of the human PWP2 gene on chromosome 21.
Genomics 1997;42(3):528-31.
1997: Chrast R; Scott H S; Chen H; Kudoh J; Rossier C; Minoshima S; Wang Y; Shimizu N; Antonarakis S E
Cloning of two human homologs of the Drosophila single-minded gene SIM1 on chromosome 6q and SIM2 on 21q within the Down syndrome chromosomal region.
Genome research 1997;7(6):615-24.
1997: Nagamine K; Kudoh J; Kawasaki K; Minoshima S; Asakawa S; Ito F; Shimizu N
Genomic organization and complete nucleotide sequence of the TMEM1 gene on human chromosome 21q22.3.
Biochemical and biophysical research communications 1997;235(1):185-90.
1997: Asakawa S; Abe I; Kudoh Y; Kishi N; Wang Y; Kubota R; Kudoh J; Kawasaki K; Minoshima S; Shimizu N
Human BAC library: construction and rapid screening.
Gene 1997;191(1):69-79.
1997: Kubota R; Noda S; Wang Y; Minoshima S; Asakawa S; Kudoh J; Mashima Y; Oguchi Y; Shimizu N
A novel myosin-like protein (myocilin) expressed in the connecting cilium of the photoreceptor: molecular cloning, tissue expression, and chromosomal mapping.
Genomics 1997;41(3):360-9.
1997: Imamura Y; Kubota R; Wang Y; Asakawa S; Kudoh J; Mashima Y; Oguchi Y; Shimizu N
Human retina-specific amine oxidase (RAO): cDNA cloning, tissue expression, and chromosomal mapping.
Genomics 1997;40(2):277-83.
1997: Kawasaki K; Minoshima S; Nakato E; Shibuya K; Shintani A; Schmeits J L; Wang J; Shimizu N
One-megabase sequence analysis of the human immunoglobulin lambda gene locus.
Genome research 1997;7(3):250-61.
1997: Kudoh J; Nagamine K; Asakawa S; Abe I; Kawasaki K; Maeda H; Tsujimoto S; Minoshima S; Ito F; Shimizu N
Localization of 16 exons to a 450-kb region involved in the autoimmune polyglandular disease type I (APECED) on human chromosome 21q22.3.
DNA research : an international journal for rapid publication of reports on genes and genomes 1997;4(1):45-52.
1996: Shimizu N
[Prospects of the human chromosome research]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2510-1.
1996: Shimizu N
[Gene therapy: current status and prospects]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2491-3.
1996: Minoshima S; Shimizu N
[Genetic information database]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2464-77.
1996: Kawasaki K; Shimizu N
[Shotgun sequencing]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2458-63.
1996: Kudoh J; Shimizu N
[Physical mapping of human chromosome]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2414-23.
1996: Minoshima S; Shimizu N
[Analysis of disease-associated marker chromosomes using chromosome sorter]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1996;41(15 Suppl):2174-81.
1996: Wang Y; Kudoh J; Kubota R; Asakawa S; Minoshima S; Shimizu N
Chromosomal mapping of a family of human glutamine synthetase genes: functional gene (GLUL) on 1q25, pseudogene (GLULP) on 9p13, and three related genes (GLULL1, GLULL2, GLULL3) on 5q33, 11p15, and 11q24.
Genomics 1996;37(2):195-9.
1996: Amagai M; Ishii K; Takayanagi A; Nishikawa T; Shimizu N
Transport to endoplasmic reticulum by signal peptide, but not proteolytic processing, is required for formation of conformational epitopes of pemphigus vulgaris antigen (Dsg3).
The Journal of investigative dermatology 1996;107(4):539-42.
1996: Shindoh N; Kudoh J; Maeda H; Yamaki A; Minoshima S; Shimizu Y; Shimizu N
Cloning of a human homolog of the Drosophila minibrain/rat Dyrk gene from "the Down syndrome critical region" of chromosome 21.
Biochemical and biophysical research communications 1996;225(1):92-9.
1996: Nagamine K; Kudoh J; Minoshima S; Kawasaki K; Asakawa S; Ito F; Shimizu N
Isolation of cDNA for a novel human protein KNP-I that is homologous to the E. coli SCRP-27A protein from the autoimmune polyglandular disease type I (APECED) region of chromosome 21q22.3.
Biochemical and biophysical research communications 1996;225(2):608-16.
1996: Yamaki A; Noda S; Kudoh J; Shindoh N; Maeda H; Minoshima S; Kawasaki K; Shimizu Y; Shimizu N
The mammalian single-minded (SIM) gene: mouse cDNA structure and diencephalic expression indicate a candidate gene for Down syndrome.
Genomics 1996;35(1):136-43.
1996: Gamou S; Shimizu N
[Expression of EGF receptor subfamily in tumor]
Nippon rinsho. Japanese journal of clinical medicine 1996;54(6):1521-8.
1996: Shimizu N; Chen J; Gamou S; Takayanagi A
Immunogene approach toward cancer therapy using erythrocyte growth factor receptor-mediated gene delivery.
Cancer gene therapy 1996;3(2):113-20.
1995: Gamou S; Chen J; Takayanagi A; Shimizu N
[Gene delivery by immunogene and its application to cancer gene therapy]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1995;40(17):2562-9.
1995: Hattori N; Suzuki H; Wang Y; Minoshima S; Shimizu N; Yoshino H; Kurashima R; Tanaka M; Ozawa T; Mizuno Y
Structural organization and chromosomal localization of the human nuclear gene (NDUFV2) for the 24-kDa iron-sulfur subunit of complex I in mitochondrial respiratory chain.
Biochemical and biophysical research communications 1995;216(3):771-7.
1995: Kawasaki K; Minoshima S; Schooler K; Kudoh J; Asakawa S; de Jong P J; Shimizu N
The organization of the human immunoglobulin lambda gene locus.
Genome research 1995;5(2):125-35.
1995: Wang Y; Minoshima S; Shimizu N
Cot-1 banding of human chromosomes using fluorescence in situ hybridization with Cy3 labeling.
The Japanese journal of human genetics 1995;40(3):243-52.
1995: Amagai M; Ishii K; Hashimoto T; Gamou S; Shimizu N; Nishikawa T
Conformational epitopes of pemphigus antigens (Dsg1 and Dsg3) are calcium dependent and glycosylation independent.
The Journal of investigative dermatology 1995;105(2):243-7.
1995: Mashima Y; Saga M; Hiida Y; Oguchi Y; Wakakura M; Kudoh J; Shimizu N
Quantitative determination of heteroplasmy in Leber's hereditary optic neuropathy by single-strand conformation polymorphism.
Investigative ophthalmology & visual science 1995;36(8):1714-20.
1995: Hiida Y; Mashima Y; Saga M; Shuu M; Akiya S; Kudoh J; Shimizu N; Oguchi Y
[Molecular genetic analysis of Leber's hereditary optic neuropathy with the 3460 mutation in Japanese pedigrees]
Nippon Ganka Gakkai zasshi 1995;99(6):728-34.
1995: Amagai M; Hashimoto T; Green K J; Shimizu N; Nishikawa T
Antigen-specific immunoadsorption of pathogenic autoantibodies in pemphigus foliaceus.
The Journal of investigative dermatology 1995;104(6):895-901.
1995: Hashimoto T; Gamou S; Shimizu N; Kitajima Y; Nishikawa T
Regulation of translocation of the desmoyokin/AHNAK protein to the plasma membrane in keratinocytes by protein kinase C.
Experimental cell research 1995;217(2):258-66.
1995: Sakai K; Ohta T; Minoshima S; Kudoh J; Wang Y; de Jong P J; Shimizu N
Human ribosomal RNA gene cluster: identification of the proximal end containing a novel tandem repeat sequence.
Genomics 1995;26(3):521-6.
1995: Kubota R; Wang Y; Minoshima S; Kudoh J; Mashima Y; Oguchi Y; Shimizu N
Mapping of the human gene for a melanocyte protein Pmel 17 (D12S53E) to chromosome 12q13-q14.
Genomics 1995;26(2):430-1.
1995: Mashima Y; Hiida Y; Saga M; Oguchi Y; Kudoh J; Shimizu N
Risk of false-positive molecular genetic diagnosis of Leber's hereditary optic neuropathy.
American journal of ophthalmology 1995;119(2):245-6.
1995: Gamou S; Shimizu N
Hydrogen peroxide preferentially enhances the tyrosine phosphorylation of epidermal growth factor receptor.
FEBS letters 1995;357(2):161-4.
1995: Amagai M; Wang Y; Minoshima S; Kawamura K; Green K J; Nishikawa T; Shimizu N
Assignment of the human genes for desmocollin 3 (DSC3) and desmocollin 4 (DSC4) to chromosome 18q12.
Genomics 1995;25(1):330-2.
1995: Amagai M; Fujimori T; Masunaga T; Shimizu H; Nishikawa T; Shimizu N; Takeichi M; Hashimoto T
Delayed assembly of desmosomes in keratinocytes with disrupted classic-cadherin-mediated cell adhesion by a dominant negative mutant.
The Journal of investigative dermatology 1995;104(1):27-32.
1995: Minoshima S; Wang Y; Ichida K; Nishino T; Shimizu N
Mapping of the gene for human xanthine dehydrogenase (oxidase) (XDH) to band p23 of chromosome 2.
Cytogenetics and cell genetics 1995;68(1-2):52-3.
1995: Kudoh J; Wang Y; Minoshima S; Hashimoto T; Amagai M; Nishikawa T; Shtivelman E; Bishop J M; Shimizu N
Localization of the human AHNAK/desmoyokin gene (AHNAK) to chromosome band 11q12 by somatic cell hybrid analysis and fluorescence in situ hybridization.
Cytogenetics and cell genetics 1995;70(3-4):218-20.
1994: Fujita N; Tamura S; Shimizu N; Nozawa S
Genetic origin analysis of hydatidiform mole and non-molar abortion using the polymerase chain reaction method.
Acta obstetricia et gynecologica Scandinavica 1994;73(9):719-25.
1994: Dmochowski M; Hashimoto T; Amagai M; Kudoh J; Shimizu N; Koch P J; Franke W W; Nishikawa T
The extracellular aminoterminal domain of bovine desmoglein 1 (Dsg1) is recognized only by certain pemphigus foliaceus sera, whereas its intracellular domain is recognized by both pemphigus vulgaris and pemphigus foliaceus sera.
The Journal of investigative dermatology 1994;103(2):173-7.
1994: Gamou S; Shimizu N
Light-dependent induction of early-response gene expression by calphostin-C.
Cell structure and function 1994;19(4):195-200.
1994: Amagai M; Hashimoto T; Shimizu N; Nishikawa T
Absorption of pathogenic autoantibodies by the extracellular domain of pemphigus vulgaris antigen (Dsg3) produced by baculovirus.
The Journal of clinical investigation 1994;94(1):59-67.
1994: Shimizu N; Nakamura H; Kadota T; Kitajima K; Oda T; Hirano T; Utiyama H
Loss of amplified c-myc genes in the spontaneously differentiated HL-60 cells.
Cancer research 1994;54(13):3561-7.
1994: Shimizu N; Wang Y; Minoshima S; Ishitoya J
Detection of epidermal growth factor receptor gene amplification in human squamous cell carcinomas using fluorescence in situ hybridization.
Japanese journal of cancer research : Gann 1994;85(6):567-71.
1994: Saga M; Mashima Y; Akeo K; Oguchi Y; Kudoh J; Shimizu N
Autosomal dominant retinitis pigmentosa. A mutation in codon 181 (Glu-->Lys) of the rhodopsin gene in a Japanese family.
Ophthalmic genetics 1994;15(2):61-7.
1994: Wang Y; Amagai M; Minoshima S; Sakai K; Green K J; Nishikawa T; Shimizu N
The human genes for desmogleins (DSG1 and DSG3) are located in a small region on chromosome 18q12.
Genomics 1994;20(3):492-5.
1994: Chen J; Gamou S; Takayanagi A; Shimizu N
A novel gene delivery system using EGF receptor-mediated endocytosis.
FEBS letters 1994;338(2):167-9.
1994: Gamou S; Shimizu N
Calphostin-C stimulates epidermal growth factor receptor phosphorylation and internalization via light-dependent mechanism.
Journal of cellular physiology 1994;158(1):151-9.
1993: Mashima Y; Hiida Y; Kubota R; Oguchi Y; Kudoh J; Shimizu N
DNA diagnosis of Leber's hereditary optic neuropathy by using dried blood specimens.
American journal of ophthalmology 1993;116(6):773-4.
1993: Wang Y; Minoshima S; Shimizu N
Precise mapping of the EGF receptor gene on the human chromosome 7p12 using an improved fish technique.
The Japanese journal of human genetics 1993;38(4):399-406.
1993: Shimizu N; Minoshima S; Kudoh J; Kawasaki K; Wang Y; Shimizu Y; Sakai K
Human gene mapping and chromosome sorting by laser technology.
The Keio journal of medicine 1993;42(4):212-6.
1993: Saga M; Mashima Y; Akeo K; Oguchi Y; Kudoh J; Shimizu N
A novel Cys-214-Ser mutation in the peripherin/RDS gene in a Japanese family with autosomal dominant retinitis pigmentosa.
Human genetics 1993;92(5):519-21.
1993: Toda M; Shirao T; Minoshima S; Shimizu N; Toya S; Uyemura K
Molecular cloning of cDNA encoding human drebrin E and chromosomal mapping of its gene.
Biochemical and biophysical research communications 1993;196(1):468-72.
1993: Minoshima S; Shimizu N
[Application of the chromosome sorting technique to the human genome analysis]
Nippon rinsho. Japanese journal of clinical medicine 1993;51(9):2234-9.
1993: Oda T; Kitajima K; Hirano T; Shimizu N; Utiyama H
Interplay between differentiation and cell cycle arrest at G1 in phorbol diester-treated human myelocytic leukemia cells.
International journal of hematology 1993;58(1-2):125-8.
1993: Mashima Y; Hiida Y; Oguchi Y; Kudoh J; Shimizu N
High frequency of mutations at position 11778 in mitochondrial ND4 gene in Japanese families with Leber's hereditary optic neuropathy.
Human genetics 1993;92(1):101-2.
1993: Hashimoto T; Amagai M; Ebihara T; Gamou S; Shimizu N; Tsubata T; Hasegawa A; Miki K; Nishikawa T
Further analyses of epitopes for human monoclonal anti-basement membrane zone antibodies produced by stable human hybridoma cell lines constructed with Epstein-Barr virus transformants.
The Journal of investigative dermatology 1993;100(3):310-5.
1993: Shimizu N; Minoshima S; Kudoh J; Kawasaki K
[Human genome analysis using chromosome sorting]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1993;38(3):268-77.
1993: Ebihara T; Hashimoto T; Kudoh J; Gamou S; Shimizu N; Nishikawa T
Detection of the 170-kDa bullous pemphigoid antigen by immunoprecipitation.
The Journal of investigative dermatology 1993;100(2):176-9.
1992: Shimizu N
[Applications of flow cytometry to molecular biology and molecular genetics]
Nippon rinsho. Japanese journal of clinical medicine 1992;50(10):2319-23.
1992: Sakai K; Hirai M; Kudoh J; Minoshima S; Shimizu N
Molecular cloning and chromosomal mapping of a cDNA encoding human 80K-L protein: major substrate for protein kinase C.
Genomics 1992;14(1):175-8.
1992: Gamou S; Shimizu N
[Epidermal growth factor and its receptor: the structure and function]
Nippon rinsho. Japanese journal of clinical medicine 1992;50(8):1885-92.
1992: Fukuyama R; Shimizu N
Detection of variation in the ribosomal RNA gene clusters by a modified fluorescence in situ hybridization method.
The Japanese journal of human genetics 1992;37(2):139-43.
1992: Shimizu N; Ohta M; Fujiwara C; Sagara J; Mochizuki N; Oda T; Utiyama H
A gene coding for a zinc finger protein is induced during 12-O-tetradecanoylphorbol-13-acetate-stimulated HL-60 cell differentiation.
Journal of biochemistry 1992;111(2):272-7.
1992: Oguro K; Sakamoto K; Kitajima K; Oda T; Hirano T; Shimizu N; Utiyama H
Determination of transcriptional activities of typical gene promoters in HL-60 cells.
Journal of biochemistry 1992;111(1):103-8.
1992: Kawasaki K; Minoshima S; Kudoh J; Fukuyama R; Shimizu N
Methylation status of ribosomal RNA gene clusters in the flow-sorted human acrocentric chromosomes.
Mammalian genome : official journal of the International Mammalian Genome Society 1992;3(3):173-8.
1991: Osaku M; Ueda M; Ando N; Shinozawa Y; Hirota N; Shimizu N; Abe O
Targeted killing of squamous carcinoma cells by a monoclonal antibody-peplomycin conjugate which recognizes the EGF receptor.
Anticancer research 1991;11(6):1951-6.
1991: Tanaka M; Hashimoto T; Amagai M; Shimizu N; Ikeguchi N; Tsubata T; Hasegawa A; Miki K; Nishikawa T
Characterization of bullous pemphigoid antibodies by use of recombinant bullous pemphigoid antigen proteins.
The Journal of investigative dermatology 1991;97(4):725-8.
1991: Fukuyama R; Ichijoh Y; Minoshima S; Kitamura N; Shimizu N
Regional localization of the hepatocyte growth factor (HGF) gene to human chromosome 7 band q21.1.
Genomics 1991;11(2):410-5.
1991: Okuyama T; Matsuo N; Kudoh J; Shimizu N
A ScrFI polymorphism in the human ALPL gene.
Nucleic acids research 1991;19(18):5090.
1991: Shimizu N; Ohta M; Fujiwara C; Sagara J; Mochizuki N; Oda T; Utiyama H
Expression of a novel immediate early gene during 12-O-tetradecanoylphorbol-13-acetate-induced macrophagic differentiation of HL-60 cells.
The Journal of biological chemistry 1991;266(19):12157-61.
1991: Fukuyama R; Takata M; Kudoh J; Sakai K; Tamura S; Shimizu N
DNA diagnosis of hydatidiform mole using the polymerase chain reaction.
Human genetics 1991;87(2):216-8.
1991: Fukuyama R; Shimizu N
Expression of epidermal growth factor (EGF) and the EGF receptor in human tissues.
The Journal of experimental zoology 1991;258(3):336-43.
1991: Gamou S; Shimizu N
[The regulatory mechanism of EGF receptor gene expression]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):994-1000.
1991: Shimizu N
[Growth factors: recent advances and perspectives]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):971-7.
1991: Ueda M; Abe O; Shimizu N
[Targeting therapy directed against growth factor receptor]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1436-42.
1991: Fukuyama R; Shimizu N
[Distribution of growth factor receptors in various human tissues]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1282-91.
1991: Hirai M; Shimizu N
[Roles of protein kinase C substrates in signal transduction]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1991;36(7):1049-55.
1991: Fukuyama R; Minoshima S; Ochiai A; Tahara E; Shimizu N
Flow cytometric analysis of the expression of 9A3 antigen, E-cadherin and EGF receptor in TMK-1 stomach cancer cells.
International journal of cancer. Journal international du cancer 1991;48(1):81-4.
1991: Araki K; Matsuo N; Kodoh J; Shimizu N
RFLPs at the PAH (phenylalanine hydroxylase) gene in the Japanese population.
Nucleic acids research 1991;19(8):1960.
1991: Kitagawa Y; Ueda M; Ando N; Shinozawa Y; Shimizu N; Abe O
Significance of int-2/hst-1 coamplification as a prognostic factor in patients with esophageal squamous carcinoma.
Cancer research 1991;51(5):1504-8.
1991: Nanko S; Kobayashi M; Gamou S; Kudoh J; Shimizu N; Takazawa N; Kazamatsuri H; Furusho T
Linkage analysis of affective disorder using DNA markers on chromosomes 11 and X.
The Japanese journal of psychiatry and neurology 1991;45(1):53-6.
1991: Okuyama T; Matsuo N; Kudoh J; Shimizu N
PCR detection of a BclI RFLP in the human ALPL gene.
Nucleic acids research 1991;19(5):1166.
1991: Fukuyama R; Shimizu N
Detection of epidermal growth factor receptors and E-cadherins in the basolateral membrane of A431 cells by laser scanning fluorescence microscopy.
Japanese journal of cancer research : Gann 1991;82(1):8-11.
1991: Hiida Y; Mashima Y; Oguchi Y; Uemura Y; Kudoh J; Sakai K; Shimizu N
Mitochondrial DNA analysis of Leber's hereditary optic neuropathy.
Japanese journal of ophthalmology 1991;35(1):102-6.
1991: Minoshima S; Amagai M; Kudoh J; Fukuyama R; Hashimoto T; Nishikawa T; Shimizu N
Localization of the human gene for 230-kDal bullous pemphigoid autoantigen (BPAG1) to chromosome 6pter----q15.
Cytogenetics and cell genetics 1991;57(1):30-2.
1990: Amagai M; Hashimoto T; Tajima S; Inokuchi Y; Shimizu N; Saito M; Miki K; Nishikawa T
Partial cDNA cloning of the 230-kD mouse bullous pemphigoid antigen by use of a human monoclonal anti-basement membrane zone antibody.
The Journal of investigative dermatology 1990;95(3):252-9.
1990: Gamou S; Shimizu N
[Growth factors and cell transformation]
Nippon rinsho. Japanese journal of clinical medicine 1990;48(8):111-8.
1990: Gamou S; Shimosato Y; Shimizu N
Regulation of the epidermal growth factor receptor gene expression in a morphological variant isolated from an epidermal growth factor receptor-deficient small cell lung carcinoma cell line.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1990;1(8):351-9.
1990: Mashima Y; Oguchi Y; Uemura Y; Kudoh J; Sakai K; Shimizu N
[DNA diagnosis of Leber's hereditary optic neuropathy]
Nippon Ganka Gakkai zasshi 1990;94(7):683-7.
1990: Kikuchi A; Amagai M; Hayakawa K; Ueda M; Hirohashi S; Shimizu N; Nishikawa T
Association of EGF receptor expression with proliferating cells and of ras p21 expression with differentiating cells in various skin tumours.
The British journal of dermatology 1990;123(1):49-58.
1990: Minoshima S; Kawasaki K; Fukuyama R; Maekawa M; Kudoh J; Shimizu N
Isolation of giant DNA fragments from flow-sorted human chromosomes.
Cytometry 1990;11(4):539-46.
1990: Amagai M; Hayakawa K; Amagai N; Kobayashi K; Onodera Y; Shimizu N; Nishikawa T
T cell receptor gene rearrangement analysis in mycosis fungoides and disseminated lymphocytoma cutis.
Dermatologica 1990;181(3):193-6.
1989: Yanagawa T; Maruyama T; Takei I; Asaba Y; Takahashi T; Ishii T; Kataoka K; Saruta T; Minoshima S; Shimizu N
The suppressive effect of cyclophosphamide on low-dose streptozotocin-induced diabetes in mice.
Diabetes research (Edinburgh, Scotland) 1989;12(2):79-83.
1989: Ueda M; Shimizu N; Abe O
[Amplification and expression of oncogenes in human malignant tumors--organ or tissue specificity and prognosis]
Nippon Geka Gakkai zasshi 1989;90(9):1579-81.
1989: Sakai K; Hirai M; Minoshima S; Kudoh J; Fukuyama R; Shimizu N
Isolation of cDNAs encoding a substrate for protein kinase C: nucleotide sequence and chromosomal mapping of the gene for a human 80K protein.
Genomics 1989;5(2):309-15.
1989: Gamou S; Shimagaki M; Minoshima S; Kobayashi S; Shimizu N
Subcellular localization of the EGF receptor maturation process.
Experimental cell research 1989;183(1):197-206.
1989: Gamou S; Kobayashi M; Furusho T; Shimizu N
Unique chromosomal location of amplified EGF receptor genes in EGF receptor-hyperproducing tumor cell line NA.
Somatic cell and molecular genetics 1989;15(2):179-84.
1989: Amagai M; Inokuchi Y; Nishikawa T; Shimizu Y; Shimizu N
Cloning of TPA-inducible early (TIE) genes by differential hybridization using TPA-nonresponsive variant of mouse 3T3-L1 cells.
Somatic cell and molecular genetics 1989;15(2):153-8.
1989: Hirai M; Gamou S; Kobayashi M; Shimizu N
Lung cancer cells often express high levels of protein kinase C activity.
Japanese journal of cancer research : Gann 1989;80(3):204-8.
1989: Ozawa S; Ueda M; Ando N; Abe O; Minoshima S; Shimizu N
Selective killing of squamous carcinoma cells by an immunotoxin that recognizes the EGF receptor.
International journal of cancer. Journal international du cancer 1989;43(1):152-7.
1988: Amagai M; Ozawa S; Ueda M; Nishikawa T; Abe O; Shimizu N
Distribution of EGF receptor expressing and DNA replicating epidermal cells in psoriasis vulgaris and Bowen's disease.
The British journal of dermatology 1988;119(5):661-8.
1988: Ozawa S; Ueda M; Ando N; Abe O; Shimizu N
Epidermal growth factor receptors in cancer tissues of esophagus, lung, pancreas, colorectum, breast and stomach.
Japanese journal of cancer research : Gann 1988;79(11):1201-7.
1988: Kawasaki K; Kudoh J; Omoto K; Shimizu N
Mega base map of the epidermal growth factor (EGF) receptor gene flanking regions and structure of the amplification units in EGF receptor-hyperproducing squamous carcinoma cells.
Japanese journal of cancer research : Gann 1988;79(11):1174-83.
1988: Gamou S; Shimizu N
Glycosylation of the epidermal growth factor receptor and its relationship to membrane transport and ligand binding.
Journal of biochemistry 1988;104(3):388-96.
1988: Gamou S; Shimosato Y; Merlino G T; Shimizu N
Methylation status of epidermal growth factor receptor gene in lung carcinoma cells.
Japanese journal of cancer research : Gann 1988;79(9):989-95.
1988: Hirai M; Gamou S; Minoshima S; Shimizu N
Two independent mechanisms for escaping epidermal growth factor-mediated growth inhibition in epidermal growth factor receptor-hyperproducing human tumor cells.
The Journal of cell biology 1988;107(2):791-9.
1988: Gamou S; Hirai M; Rikimaru K; Enomoto S; Shimizu N
Biosynthesis of the epidermal growth factor receptor in human squamous cell carcinoma lines: secretion of the truncated receptor is not common to epidermal growth factor receptor-hyperproducing cells.
Cell structure and function 1988;13(1):25-38.
1987: Ozawa S; Ueda M; Ando N; Abe O; Hirai M; Shimizu N
Stimulation by EGF of the growth of EGF receptor-hyperproducing tumor cells in athymic mice.
International journal of cancer. Journal international du cancer 1987;40(5):706-10.
1978: Satoh K; Shimizu N; Tohyama M; Maeda T
Localization of the micturition reflex center at dorsolateral pontine tegmentum of the rat.
Neuroscience letters 1978;8(1):27-33.
1978: Satoh K; Tohyama M; Sakumoto T; Yamamoto K; Shimizu N
Descending projection of the nucleus tegmentalis latero-dorsalis to the spinal cord; studied by the horseradish peroxidase method following 6-hydroxy-DOPA administration.
Neuroscience letters 1978;8(1):9-15.

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