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Sakayu Shimizu

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Genes & Molecular Sequences

Amino Acid Sequences

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Makoto Hibi; Takashi Kawashima; Tomohiro Kodera; Sakayu Shimizu; Sergey V Smirnov; Pavel M Sokolov; Masakazu Sugiyama; Kenzo Yokozeki; Jun Ogawa
L-leucine 5-hydroxylase of Nostoc punctiforme is a novel type of Fe(II)/α-ketoglutarate-dependent dioxygenase that is useful as a biocatalyst.
Dayong Si; Nobuyuki Urano; Sakayu Shimizu; Michihiko Kataoka
LplR, a repressor belonging to the TetR family, regulates expression of the L-pantoyl lactone dehydrogenase gene in Rhodococcus erythropolis.
Feng Hou; Michihiko Kataoka; Takuya Miyakawa; Koji Nagata; Sakayu Shimizu; Daijiro Takeshita; Atsuko Uzura; Masaru Tanokura
Expression, purification, crystallization and X-ray analysis of 3-quinuclidinone reductase from Agrobacterium tumefaciens.

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All Publications

2013: Makoto Hibi; Takashi Kawashima; Tomohiro Kodera; Sakayu Shimizu; Sergey V Smirnov; Pavel M Sokolov; Masakazu Sugiyama; Kenzo Yokozeki; Jun Ogawa
L-leucine 5-hydroxylase of Nostoc punctiforme is a novel type of Fe(II)/α-ketoglutarate-dependent dioxygenase that is useful as a biocatalyst.
Applied microbiology and biotechnology 2013;97(6):2467-72.
2012: Dayong Si; Nobuyuki Urano; Sakayu Shimizu; Michihiko Kataoka
LplR, a repressor belonging to the TetR family, regulates expression of the L-pantoyl lactone dehydrogenase gene in Rhodococcus erythropolis.
Applied and environmental microbiology 2012;78(22):7923-30.
2012: Feng Hou; Michihiko Kataoka; Takuya Miyakawa; Koji Nagata; Sakayu Shimizu; Daijiro Takeshita; Atsuko Uzura; Masaru Tanokura
Expression, purification, crystallization and X-ray analysis of 3-quinuclidinone reductase from Agrobacterium tumefaciens.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 10):1237-9.
2012: Yasutaka Sasaki; Nobuyuki Urano; Junzo Hasegawa; Kimiyasu Isobe; Akira Iwasaki; Michihiko Kataoka; Jun Ogawa; Sakayu Shimizu
Cloning and sequencing of a gene encoding of aldehyde oxidase in Pseudomonas sp. AIU 362.
Journal of bioscience and bioengineering 2012;114(1):28-32.
2012: Akasit Siriphongphaew; Vlada B Urlacher; Alisa S Vangnai; Jirarut Wongkongkatep; Kohsuke Honda; Pranee Inprakhon; Junichi Kato; Jun Ogawa; Hisao Ohtake; Pimpaya Pisnupong; Rolf D Schmid; Sakayu Shimizu; Thunyarat Pongtharangkul
Development of a whole-cell biocatalyst co-expressing P450 monooxygenase and glucose dehydrogenase for synthesis of epoxyhexane.
Applied microbiology and biotechnology 2012;95(2):357-67.
2012: Dayong Si; Nobuyuki Urano; Kohsuke Honda; Shinya Nozaki; Sakayu Shimizu; Michihiko Kataoka
L-pantoyl lactone dehydrogenase from Rhodococcus erythropolis: genetic analyses and application to the stereospecific oxidation of L-pantoyl lactone.
Applied microbiology and biotechnology 2012;95(2):431-40.
2012: Sergey V Smirnov; Pavel M Sokolov; Masakazu Sugiyama; Kenzo Yokozeki; Makoto Hibi; Tomohiro Kodera; Sakayu Shimizu; Jun Ogawa
A novel family of bacterial dioxygenases that catalyse the hydroxylation of free L-amino acids.
FEMS microbiology letters 2012;331(2):97-104.
2012: Yoichi Suwa; Yoshihiko Yasohara; Fabiana Lica Imai; Michihiko Kataoka; Takuya Miyakawa; Jun Ohtsuka; Masahiko Okai; Yoriko Sawano; Sakayu Shimizu; Masaru Tanokura
Expression, purification, crystallization and preliminary X-ray analysis of carbonyl reductase S1 from Candida magnoliae.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 5):540-2.
2012: Akihito Nakanishi; Masato Nakatani; Jun Ogawa; Sakayu Shimizu; Naoki Tokumoto; Jun Gu Bae; Kotaro Fukai; Kouichi Kuroda; Mitsuyoshi Ueda
Effect of pretreatment of hydrothermally processed rice straw with laccase-displaying yeast on ethanol fermentation.
Applied microbiology and biotechnology 2012;94(4):939-48.
2012: Dayong Si; Nobuyuki Urano; Sakayu Shimizu; Michihiko Kataoka
Cloning and overexpression of ketopantoic acid reductase gene from Stenotrophomonas maltophilia and its application to stereospecific production of D-pantoic acid.
Applied microbiology and biotechnology 2012;93(4):1619-25.
2012: Kimiyasu Isobe; Michihiko Kataoka; Jun Ogawa; Junzo Hasegawa; Sakayu Shimizu
Microbial oxidases catalyzing conversion of glycolaldehyde into glyoxal.
New biotechnology 2012;29(2):177-82.
2012: Nobuyuki Horinouchi; Takako Kawano; Seiichiro Matsumoto; Takafumi Sakai; Mie Sasaki; Jun Shima; Sakayu Shimizu; Makoto Hibi; Jun Ogawa
Construction of microbial platform for an energy-requiring bioprocess: practical 2'-deoxyribonucleoside production involving a C-C coupling reaction with high energy substrates.
Microbial cell factories 2012;11():82.
2012: Takashi Mimitsuka; Shinichi Minegishi; Ken Morita; Kyungsu Na; Hideki Sawai; Sakayu Shimizu; Katsushige Yamada; Masahiro Henmi; Tetsu Yonehara
A membrane-integrated fermentation reactor system: its effects in reducing the amount of sub-raw materials for D-lactic acid continuous fermentation by Sporolactobacillus laevolacticus.
Bioscience, biotechnology, and biochemistry 2012;76(1):67-72.
2011: Makoto Hibi; Takashi Kawashima; Tomohiro Kodera; Sakayu Shimizu; Sergey V Smirnov; Pavel M Sokolov; Masakazu Sugiyama; Kenzo Yokozeki; Jun Ogawa
Characterization of Bacillus thuringiensis L-isoleucine dioxygenase for production of useful amino acids.
Applied and environmental microbiology 2011;77(19):6926-30.
2011: Norihiko Misawa; Miho Nodate; Toshihiko Otomatsu; Keiko Shimizu; Chie Kaido; Miho Kikuta; Akira Ideno; Hiroshi Ikenaga; Jun Ogawa; Sakayu Shimizu; Kazutoshi Shindo
Bioconversion of substituted naphthalenes and β-eudesmol with the cytochrome P450 BM3 variant F87V.
Applied microbiology and biotechnology 2011;90(1):147-57.
2011: Nobuyuki Urano; Satoko Fukui; Shoko Kumashiro; Takeru Ishige; Shinji Kita; Keiji Sakamoto; Michihiko Kataoka; Sakayu Shimizu
Directed evolution of an aminoalcohol dehydrogenase for efficient production of double chiral aminoalcohols.
Journal of bioscience and bioengineering 2011;111(3):266-71.
2011: Jun Ogawa; Tomohiro Kodera; Sergey V Smirnov; Makoto Hibi; Natalya N Samsonova; Ryoukichi Koyama; Hiroyuki Yamanaka; Junichi Mano; Takashi Kawashima; Kenzo Yokozeki; Sakayu Shimizu
A novel L-isoleucine metabolism in Bacillus thuringiensis generating (2S,3R,4S)-4-hydroxyisoleucine, a potential insulinotropic and anti-obesity amino acid.
Applied microbiology and biotechnology 2011;89(6):1929-38.
2011: Nobuyuki Urano; Michihiko Kataoka; Takeru Ishige; Shinji Kita; Keiji Sakamoto; Sakayu Shimizu
Genetic analysis around aminoalcohol dehydrogenase gene of Rhodococcus erythropolis MAK154: a putative GntR transcription factor in transcriptional regulation.
Applied microbiology and biotechnology 2011;89(3):739-46.
2011: Shigenobu Kishino; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu
Linoleic acid isomerase in Lactobacillus plantarum AKU1009a proved to be a multi-component enzyme system requiring oxidoreduction cofactors.
Bioscience, biotechnology, and biochemistry 2011;75(2):318-22.
2010: Sergey V Smirnov; Tomohiro Kodera; Natalya N Samsonova; Veronika A Kotlyarova; Natalya Yu Rushkevich; Alexander D Kivero; Pavel M Sokolov; Makoto Hibi; Jun Ogawa; Sakayu Shimizu
Metabolic engineering of Escherichia coli to produce (2S, 3R, 4S)-4-hydroxyisoleucine.
Applied microbiology and biotechnology 2010;88(3):719-26.
2010: Masato Nakatani; Makoto Hibi; Masashi Minoda; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu
Two laccase isoenzymes and a peroxidase of a commercial laccase-producing basidiomycete, Trametes sp. Ha1.
New biotechnology 2010;27(4):317-23.
2010: Yasutaka Sasaki; Michihiko Kataoka; Nobuyuki Urano; Jun Ogawa; Akira Iwasaki; Junzo Hasegawa; Kimiyasu Isobe; Sakayu Shimizu
Cloning, sequencing and expression analysis of a gene encoding alcohol oxidase in Paenibacillus sp. AIU 311.
Journal of bioscience and bioengineering 2010;110(2):147-51.
2010: C Ohto; M Muramatsu; S Obata; Eiji Sakuradani; Sakayu Shimizu
Production of geranylgeraniol on overexpression of a prenyl diphosphate synthase fusion gene in Saccharomyces cerevisiae.
Applied microbiology and biotechnology 2010;87(4):1327-34.
2010: Shigenobu Kishino; Jun Ogawa; Akinori Ando; K Yokozeki; Sakayu Shimizu
Microbial production of conjugated gamma-linolenic acid from gamma-linolenic acid by Lactobacillus plantarum AKU 1009a.
Journal of applied microbiology 2010;108(6):2012-8.
2009: Tomohiro Kodera; Sergey V Smirnov; Natalya N Samsonova; Yury I Kozlov; Ryokichi Koyama; Makoto Hibi; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu
A novel l-isoleucine hydroxylating enzyme, l-isoleucine dioxygenase from Bacillus thuringiensis, produces (2S,3R,4S)-4-hydroxyisoleucine.
Biochemical and biophysical research communications 2009;390(3):506-10.
2009: Nobuto Matsushita; Masahiro Miyashita; Yayoi Ichiki; Takehiko Ogura; Eiji Sakuradani; Yoshiaki Nakagawa; Sakayu Shimizu; Hisashi Miyagawa
Purification and cDNA cloning of LaIT2, a novel insecticidal toxin from venom of the scorpion Liocheles australasiae.
Bioscience, biotechnology, and biochemistry 2009;73(12):2769-72.
2009: Akihiro Yamamura; Shintaro Maruoka; Jun Ohtsuka; Takuya Miyakawa; Koji Nagata; Michihiko Kataoka; Nahoko Kitamura; Sakayu Shimizu; Masaru Tanokura
Expression, purification, crystallization and preliminary X-ray analysis of conjugated polyketone reductase C2 (CPR-C2) from Candida parapsilosis IFO 0708.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 11):1145-8.
2009: Eiji Sakuradani; Sakayu Shimizu
Single cell oil production by Mortierella alpina.
Journal of biotechnology 2009;144(1):31-6.
2009: Nobuyuki Horinouchi; Takako Kawano; Takafumi Sakai; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Jun Ogawa; Sakayu Shimizu
Screening and characterization of a phosphopentomutase useful for enzymatic production of 2'-deoxyribonucleoside.
New biotechnology 2009;26(1-2):75-82.
2009: Kenro Tokuhiro; Masayoshi Muramatsu; Chikara Ohto; Toshiya Kawaguchi; Shusei Obata; Nobuhiko Muramoto; Masana Hirai; Haruo Takahashi; Akihiko Kondo; Eiji Sakuradani; Sakayu Shimizu
Overproduction of geranylgeraniol by metabolically engineered Saccharomyces cerevisiae.
Applied and environmental microbiology 2009;75(17):5536-43.
2009: Akinori Ando; Yosuke Sumida; Hiroaki Negoro; Dian Anggraini Suroto; Jun Ogawa; Eiji Sakuradani; Sakayu Shimizu
Establishment of Agrobacterium tumefaciens-mediated transformation of an oleaginous fungus, Mortierella alpina 1S-4, and its application for eicosapentaenoic acid producer breeding.
Applied and environmental microbiology 2009;75(17):5529-35.
2009: Eiji Sakuradani; Masutoshi Nojiri; Haruna Suzuki; Sakayu Shimizu
Identification of a novel fatty acid elongase with a wide substrate specificity from arachidonic acid-producing fungus Mortierella alpina 1S-4.
Applied microbiology and biotechnology 2009;84(4):709-16.
2009: Eiji Sakuradani; Akinori Ando; Jun Ogawa; Sakayu Shimizu
Improved production of various polyunsaturated fatty acids through filamentous fungus Mortierella alpina breeding.
Applied microbiology and biotechnology 2009;84(1):1-10.
2009: Shigenobu Kishino; Jun Ogawa; Kenzo Yokozeki; Sakayu Shimizu
Metabolic diversity in biohydrogenation of polyunsaturated fatty acids by lactic acid bacteria involving conjugated fatty acid production.
Applied microbiology and biotechnology 2009;84(1):87-97.
2009: Masayoshi Muramatsu; Chikara Ohto; Shusei Obata; Eiji Sakuradani; Sakayu Shimizu
Alkaline pH enhances farnesol production by Saccharomyces cerevisiae.
Journal of bioscience and bioengineering 2009;108(1):52-5.
2009: Daijiro Takeshita; Michihiko Kataoka; Takuya Miyakawa; Ken-ichi Miyazono; Atsuko Uzura; Koji Nagata; Sakayu Shimizu; Masaru Tanokura
Crystallization and preliminary X-ray analysis of the NADPH-dependent 3-quinuclidinone reductase from Rhodotorula rubra.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 6):645-7.
2009: Akinori Ando; Eiji Sakuradani; Kota Horinaka; Jun Ogawa; Sakayu Shimizu
Transformation of an oleaginous zygomycete Mortierella alpina 1S-4 with the carboxin resistance gene conferred by mutation of the iron-sulfur subunit of succinate dehydrogenase.
Current genetics 2009;55(3):349-56.
2009: Atsuko Uzura; Fumiki Nomoto; Akiko Sakoda; Yukifumi Nishimoto; Michihiko Kataoka; Sakayu Shimizu
Stereoselective synthesis of (R)-3-quinuclidinol through asymmetric reduction of 3-quinuclidinone with 3-quinuclidinone reductase of Rhodotorula rubra.
Applied microbiology and biotechnology 2009;83(4):617-26.
2009: Eiji Sakuradani; Akinori Ando; Jun Ogawa; Sakayu Shimizu
[Production of functional lipids by microorganisms: arachidonic acid and related polyunsaturated fatty acids].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2009;54(6):725-34.
2009: Akinori Ando; Jun Ogawa; S Sugimoto; Shigenobu Kishino; Eiji Sakuradani; K Yokozeki; Sakayu Shimizu
Selective production of cis-9,trans-11 isomer of conjugated linoleic acid from trans-vaccenic acid methyl ester by Delacroixia coronata.
Journal of applied microbiology 2009;106(5):1697-704.
2009: Chikara Ohto; Masayoshi Muramatsu; Shusei Obata; Eiji Sakuradani; Sakayu Shimizu
Overexpression of the gene encoding HMG-CoA reductase in Saccharomyces cerevisiae for production of prenyl alcohols.
Applied microbiology and biotechnology 2009;82(5):837-45.
2009: Kimiyasu Isobe; Toyofumi Takahashi; Jun Ogawa; Michihiko Kataoka; Sakayu Shimizu
Production and characterization of alcohol oxidase from Penicillium purpurescens AIU 063.
Journal of bioscience and bioengineering 2009;107(2):108-12.
2009: Eiji Sakuradani; Takahiro Abe; Kenji Matsumura; Akiko Tomi; Sakayu Shimizu
Identification of mutation sites on Delta12 desaturase genes from Mortierella alpina 1S-4 mutants.
Journal of bioscience and bioengineering 2009;107(2):99-101.
2009: Eiji Sakuradani; Takahiro Abe; Sakayu Shimizu
Identification of mutation sites on omega3 desaturase genes from Mortierella alpina 1S-4 mutants.
Journal of bioscience and bioengineering 2009;107(1):7-9.
2009: C Ohto; M Muramatsu; S Obata; Eiji Sakuradani; Sakayu Shimizu
Prenyl alcohol production by expression of exogenous isopentenyl diphosphate isomerase and farnesyl diphosphate synthase genes in Escherichia coli.
Bioscience, biotechnology, and biochemistry 2009;73(1):186-8.
2008: Eiji Sakuradani; Shoichi Murata; Hiroyuki Kanamaru; Sakayu Shimizu
Functional analysis of a fatty acid elongase from arachidonic acid-producing Mortierella alpina 1S-4.
Applied microbiology and biotechnology 2008;81(3):497-503.
2008: Kimiyasu Isobe; Kazuna Ishikura; Sakayu Shimizu
Identification and characterization of enzyme catalyzing conversion of N(alpha)-benzyloxycarbonyl-L-aminoadipic-delta-semialdehyde to N(alpha)-benzyloxycarbonyl-L-aminoadipic acid in Aspergillus niger AKU 3302.
Journal of bioscience and bioengineering 2008;106(4):409-11.
2008: Rungruedee Thiwthong; Michihiko Kataoka; Akira Iwasaki; Hiroshi Watanabe; Junzo Hasegawa; Kimiyasu Isobe; Sakayu Shimizu
Aldehyde oxidase carrying an unusual subunit structure from Pseudomonas sp. MX-058.
Microbial biotechnology 2008;1(5):395-402.
2008: Yasutaka Sasaki; Kimiyasu Isobe; Michihiko Kataoka; Jun Ogawa; Akira Iwasaki; Junzo Hasegawa; Sakayu Shimizu
Purification and characterization of a new aldehyde oxidase from pseudomonas sp. AIU 362.
Journal of bioscience and bioengineering 2008;106(3):297-302.
2008: M Muramatsu; C Ohto; S Obata; Eiji Sakuradani; Sakayu Shimizu
Various oils and detergents enhance the microbial production of farnesol and related prenyl alcohols.
Journal of bioscience and bioengineering 2008;106(3):263-7.
2008: Masayoshi Muramatsu; Chikara Ohto; Shusei Obata; Eiji Sakuradani; Sakayu Shimizu
Accumulation of prenyl alcohols by terpenoid biosynthesis inhibitors in various microorganisms.
Applied microbiology and biotechnology 2008;80(4):589-95.
2008: Michihiko Kataoka; Takeru Ishige; N Urano; Y Nakamura; Eiji Sakuradani; S Fukui; S Kita; Kimitoshi Sakamoto; Sakayu Shimizu
Cloning and expression of the L-1-amino-2-propanol dehydrogenase gene from Rhodococcus erythropolis, and its application to double chiral compound production.
Applied microbiology and biotechnology 2008;80(4):597-604.
2008: Kimiyasu Isobe; Ayako Kato; Yasutaka Sasaki; Michihiko Kataoka; Jun Ogawa; Akira Iwasaki; Junzo Hasegawa; Sakayu Shimizu
Superoxide dismutases exhibit oxidase activity on aldehyde alcohols similar to alcohol oxidase from Paenibacillus sp. AIU 311.
Journal of bioscience and bioengineering 2008;105(6):666-70.
2008: Masaru Wada; Kae Okabe; Michihiko Kataoka; Sakayu Shimizu; Atsushi Yokota; Hiroshi Takagi
Distribution of L-azetidine-2-carboxylate N-acetyltransferase in yeast.
Bioscience, biotechnology, and biochemistry 2008;72(2):582-6.
2008: Harald von Canstein; Jun Ogawa; Sakayu Shimizu; Jonathan R Lloyd
Secretion of flavins by Shewanella species and their role in extracellular electron transfer.
Applied and environmental microbiology 2008;74(3):615-23.
2007: Hiroki Ukitsu; Takashi Kuromori; Kiminori Toyooka; Yumi Goto; Ken Matsuoka; Eiji Sakuradani; Sakayu Shimizu; Asako Kamiya; Yuko Imura; Masahiro Yuguchi; Takuji Wada; Takashi Hirayama; Kazuo Shinozaki
Cytological and biochemical analysis of COF1, an Arabidopsis mutant of an ABC transporter gene.
Plant & cell physiology 2007;48(11):1524-33.
2007: Kimiyasu Isobe; Ayako Kato; Yasutaka Sasaki; Shuuya Suzuki; Michihiko Kataoka; Jun Ogawa; Akira Iwasaki; Junzo Hasegawa; Sakayu Shimizu
Purification and characterization of a novel alcohol oxidase from Paenibacillus sp. AIU 311.
Journal of bioscience and bioengineering 2007;104(2):124-8.
2007: Sergey V Smirnov; Natalya N Samsonova; Anna E Novikova; Nikolay G Matrosov; Natalya Y Rushkevich; Tomohiro Kodera; Jun Ogawa; Hiroyuki Yamanaka; Sakayu Shimizu
A novel strategy for enzymatic synthesis of 4-hydroxyisoleucine: identification of an enzyme possessing HMKP (4-hydroxy-3-methyl-2-keto-pentanoate) aldolase activity.
FEMS microbiology letters 2007;273(1):70-7.
2007: Jun Ogawa; Hiroyuki Yamanaka; Junichi Mano; Yuko Doi; Nobuyuki Horinouchi; Tomohiro Kodera; Noriki Nio; Sergey V Smirnov; Natalya N Samsonova; Yury I Kozlov; Sakayu Shimizu
Synthesis of 4-hydroxyisoleucine by the aldolase-transaminase coupling reaction and basic characterization of the aldolase from Arthrobacter simplex AKU 626.
Bioscience, biotechnology, and biochemistry 2007;71(7):1607-15.
2007: Kimiyasu Isobe; Ayako Kato; Jun Ogawa; Michihiko Kataoka; Akira Iwasaki; Junzo Hasegawa; Sakayu Shimizu
Characterization of alcohol oxidase from Aspergillus ochraceus AIU 031.
The Journal of general and applied microbiology 2007;53(3):177-83.
2007: Naoki Shibata; Yusuke Tomimoto; Toru Hanamura; Ryo Yamamoto; Mai Ueda; Yasufumi Ueda; Nobuhiro Mizuno; Hideaki Ogata; Hirofumi Komori; Yasuhito Shomura; Michihiko Kataoka; Sakayu Shimizu; Jun Kondo; Hideki Yamamoto; Akira Kikuchi; Yoshiki Higuchi
Crystallization and preliminary X-ray crystallographic studies of the axin DIX domain.
Acta crystallographica. Section F, Structural biology and crystallization communications 2007;63(Pt 6):529-31.
2007: Michihiko Kataoka; Kohsuke Honda; Keiji Sakamoto; Sakayu Shimizu
Microbial enzymes involved in lactone compound metabolism and their biotechnological applications.
Applied microbiology and biotechnology 2007;75(2):257-66.
2007: Masahiko Yamamoto; Changjin Zhu; Lui Yi; Zheng Rong; Yoshie Miura; Minoru Izumi; Shuhei Nakajima; Kenichi Tanamoto; Sakayu Shimizu; Naomichi Baba
Synthesis of lipid derivatives of pyrrole polyamide and their biological activity.
Bioscience, biotechnology, and biochemistry 2007;71(4):1078-82.
2007: Shuo Zhang; Eiji Sakuradani; Sakayu Shimizu
Identification of a sterol Delta7 reductase gene involved in desmosterol biosynthesis in Mortierella alpina 1S-4.
Applied and environmental microbiology 2007;73(6):1736-41.
2007: Shuo Zhang; Eiji Sakuradani; Kuni Ito; Sakayu Shimizu
Identification of a novel bifunctional delta12/delta15 fatty acid desaturase from a basidiomycete, Coprinus cinereus TD#822-2.
FEBS letters 2007;581(2):315-9.
2006: M Kataoka; Y Nakamura; N Urano; Takeru Ishige; G Shi; S Kita; K Sakamoto; Sakayu Shimizu
A novel NADP+-dependent L-1-amino-2-propanol dehydrogenase from Rhodococcus erythropolis MAK154: a promising enzyme for the production of double chiral aminoalcohols.
Letters in applied microbiology 2006;43(4):430-5.
2006: Yuzo Kojima; Eiji Sakuradani; Sakayu Shimizu
Acidolysis and glyceride synthesis reactions using fatty acids with two Pseudomonas lipases having different substrate specificities.
Journal of bioscience and bioengineering 2006;102(3):179-83.
2006: Junichi Mano; Jun Ogawa; Sakayu Shimizu
Microbial production of optically active beta-phenylalanine through stereoselective degradation of racemic beta-phenylalanine.
Bioscience, biotechnology, and biochemistry 2006;70(8):1941-6.
2006: Nobuyuki Horinouchi; Jun Ogawa; Takako Kawano; Takafumi Sakai; Kyota Saito; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Sakayu Shimizu
Biochemical retrosynthesis of 2'-deoxyribonucleosides from glucose, acetaldehyde, and a nucleobase.
Applied microbiology and biotechnology 2006;71(5):615-21.
2006: Shuo Zhang; Eiji Sakuradani; Sakayu Shimizu
Identification and production of n-8 odd-numbered polyunsaturated fatty acids by a delta12 desaturation-defective mutant of Mortierella alpina 1S-4.
Lipids 2006;41(6):623-6.
2006: Yuzo Kojima; Eiji Sakuradani; Sakayu Shimizu
Different specificity of two types of Pseudomonas lipases for C20 fatty acids with a Delta5 unsaturated double bond and their application for selective concentration of fatty acids.
Journal of bioscience and bioengineering 2006;101(6):496-500.
2006: Nobuyuki Horinouchi; Jun Ogawa; Takako Kawano; Takafumi Sakai; Kyota Saito; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Sakayu Shimizu
Efficient production of 2-deoxyribose 5-phosphate from glucose and acetaldehyde by coupling of the alcoholic fermentation system of Baker's yeast and deoxyriboaldolase-expressing Escherichia coli.
Bioscience, biotechnology, and biochemistry 2006;70(6):1371-8.
2006: Nobuyuki Horinouchi; Jun Ogawa; Takako Kawano; Takafumi Sakai; Kyota Saito; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Sakayu Shimizu
One-pot microbial synthesis of 2'-deoxyribonucleoside from glucose, acetaldehyde, and a nucleobase.
Biotechnology letters 2006;28(12):877-81.
2006: Jun Ogawa; Junichi Mano; Sakayu Shimizu
Microbial production of optically active beta-phenylalanine ethyl ester through stereoselective hydrolysis of racemic beta-phenylalanine ethyl ester.
Applied microbiology and biotechnology 2006;70(6):663-9.
2006: Takahiro Abe; Eiji Sakuradani; Takahiro Asano; Hiroyuki Kanamaru; Sakayu Shimizu
Functional characterization of Delta9 and omega9 desaturase genes in Mortierella alpina 1S-4 and its derivative mutants.
Applied microbiology and biotechnology 2006;70(6):711-9.
2006: Jun Ogawa; Chee-Leong Soong; Shigenobu Kishino; Qing-Shan Li; Nobuyuki Horinouchi; Sakayu Shimizu
Screening and industrial application of unique microbial reactions involved in nucleic acid and lipid metabolisms.
Bioscience, biotechnology, and biochemistry 2006;70(3):574-82.
2006: Ken-ichi Hashimoto; Hisashi Kawasaki; Kouki Akazawa; Jun Nakamura; Youko Asakura; Takuji Kudo; Eiji Sakuradani; Sakayu Shimizu; Tsuyoshi Nakamatsu
Changes in composition and content of mycolic acids in glutamate-overproducing Corynebacterium glutamicum.
Bioscience, biotechnology, and biochemistry 2006;70(1):22-30.
2005: Seiki Takeno; Eiji Sakuradani; Akiko Tomi; Misa Inohara-Ochiai; Hiroshi Kawashima; Sakayu Shimizu
Transformation of oil-producing fungus, Mortierella alpina 1S-4, using Zeocin, and application to arachidonic acid production.
Journal of bioscience and bioengineering 2005;100(6):617-22.
2005: Naokazu Kumura; Minoru Izumi; Shuhei Nakajima; Sakayu Shimizu; Hye-Sook Kim; Yusuke Wataya; Naomichi Baba
Synthesis and biological activity of fatty acid derivatives of quinine.
Bioscience, biotechnology, and biochemistry 2005;69(11):2250-3.
2005: Jun Ogawa; Shigenobu Kishino; Akinori Ando; Satoshi Sugimoto; Kousuke Mihara; Sakayu Shimizu
Production of conjugated fatty acids by lactic acid bacteria.
Journal of bioscience and bioengineering 2005;100(4):355-64.
2005: Seiki Takeno; Eiji Sakuradani; Akiko Tomi; Misa Inohara-Ochiai; Hiroshi Kawashima; Toshihiko Ashikari; Sakayu Shimizu
Improvement of the fatty acid composition of an oil-producing filamentous fungus, Mortierella alpina 1S-4, through RNA interference with delta12-desaturase gene expression.
Applied and environmental microbiology 2005;71(9):5124-8.
2005: Keiji Sakamoto; Kohsuke Honda; Koichi Wada; Shinji Kita; Kazuya Tsuzaki; Hanae Nose; Michihiko Kataoka; Sakayu Shimizu
Practical resolution system for DL-pantoyl lactone using the lactonase from Fusarium oxysporum.
Journal of biotechnology 2005;118(1):99-106.
2005: Woro Triarsi Sulistyaningdyah; Jun Ogawa; Qing-Shan Li; Chiharu Maeda; Yuki Yano; Rolf D Schmid; Sakayu Shimizu
Hydroxylation activity of P450 BM-3 mutant F87V towards aromatic compounds and its application to the synthesis of hydroquinone derivatives from phenolic compounds.
Applied microbiology and biotechnology 2005;67(4):556-62.
2005: Takahiro Abe; Eiji Sakuradani; Takahiro Asano; Hiroyuki Kanamaru; Yuji Ioka; Sakayu Shimizu
Identification of mutation sites on delta6 desaturase genes from Mortierella alpina 1S-4 mutants.
Bioscience, biotechnology, and biochemistry 2005;69(5):1021-4.
2005: Takeru Ishige; Kohsuke Honda; Sakayu Shimizu
Whole organism biocatalysis.
Current opinion in chemical biology 2005;9(2):174-80.
2005: Takahiro Abe; Eiji Sakuradani; Takuji Ueda; Sakayu Shimizu
Identification of mutation sites on delta5 desaturase genes from Mortierella alpina 1S-4 mutants.
Journal of bioscience and bioengineering 2005;99(3):296-9.
2005: Eiji Sakuradani; Takahiro Abe; Keita Iguchi; Sakayu Shimizu
A novel fungal omega3-desaturase with wide substrate specificity from arachidonic acid-producing Mortierella alpina 1S-4.
Applied microbiology and biotechnology 2005;66(6):648-54.
2005: Qing-Shan Li; Jun Ogawa; Rolf D Schmid; Sakayu Shimizu
Indole hydroxylation by bacterial cytochrome P450 BM-3 and modulation of activity by cumene hydroperoxide.
Bioscience, biotechnology, and biochemistry 2005;69(2):293-300.
2005: Kohsuke Honda; Hirokazu Tsuboi; Toshitaka Minetoki; Hanae Nose; Keiji Sakamoto; Michihiko Kataoka; Sakayu Shimizu
Expression of the Fusarium oxysporum lactonase gene in Aspergillus oryzae: molecular properties of the recombinant enzyme and its application.
Applied microbiology and biotechnology 2005;66(5):520-6.
2005: Seiki Takeno; Eiji Sakuradani; Shoichi Murata; Misa Inohara-Ochiai; Hiroshi Kawashima; Toshihiko Ashikari; Sakayu Shimizu
Molecular evidence that the rate-limiting step for the biosynthesis of arachidonic acid in Mortierella alpina is at the level of an elongase.
Lipids 2005;40(1):25-30.
2004: Woro Triarsi Sulistyaningdyah; Jun Ogawa; Qing-Shan Li; Raku Shinkyo; Toshiyuki Sakaki; Kuniyo Inouye; Rolf D Schmid; Sakayu Shimizu
Metabolism of polychlorinated dibenzo-p-dioxins by cytochrome P450 BM-3 and its mutant.
Biotechnology letters 2004;26(24):1857-60.
2004: Eiji Sakuradani; Yuriko Hirano; Nozomu Kamada; Masutoshi Nojiri; Jun Ogawa; Sakayu Shimizu
Improvement of arachidonic acid production by mutants with lower n-3 desaturation activity derived from Mortierella alpina.
Applied microbiology and biotechnology 2004;66(3):243-8.
2004: Michihiko Kataoka; Atsushi Kotaka; Rungruedee Thiwthong; Masaru Wada; Shigeru Nakamori; Sakayu Shimizu
Cloning and overexpression of the old yellow enzyme gene of Candida macedoniensis, and its application to the production of a chiral compound.
Journal of biotechnology 2004;114(1-2):1-9.
2004: Seiki Takeno; Eiji Sakuradani; Shoichi Murata; Misa Inohara-Ochiai; Hiroshi Kawashima; Toshihiko Ashikari; Sakayu Shimizu
Establishment of an overall transformation system for an oil-producing filamentous fungus, Mortierella alpina 1S-4.
Applied microbiology and biotechnology 2004;65(4):419-25.
2004: Jun Ogawa; Woro Triarsi Sulistyaningdyah; Qing-Shan Li; Hiromi Tanaka; Sheng-Xue Xie; Kenji Kano; Tokuji Ikeda; Sakayu Shimizu
Two extracellular proteins with alkaline peroxidase activity, a novel cytochrome c and a catalase-peroxidase, from Bacillus sp. No.13.
Biochimica et biophysica acta 2004;1699(1-2):65-75.
2004: Michihiko Kataoka; A-R G Delacruz-Hidalgo; Muhammad Ali AKOND; Eiji Sakuradani; K Kita; Sakayu Shimizu
Gene cloning and overexpression of two conjugated polyketone reductases, novel aldo-keto reductase family enzymes, of Candida parapsilosis.
Applied microbiology and biotechnology 2004;64(3):359-66.
2004: Masataka Kajikawa; Katsuyuki T Yamato; Yoshito Kohzu; Masutoshi Nojiri; Eiji Sakuradani; Sakayu Shimizu; Yasuyoshi Sakai; Fukuzawa Hideya; Kanji Ohyama
Isolation and characterization of delta(6)-desaturase, an ELO-like enzyme and delta(5)-desaturase from the liverwort Marchantia polymorpha and production of arachidonic and eicosapentaenoic acids in the methylotrophic yeast Pichia pastoris.
Plant molecular biology 2004;54(3):335-52.
2004: Seiki Takeno; Eiji Sakuradani; Shoichi Murata; Misa Inohara-Ochiai; Hiroshi Kawashima; Toshihiko Ashikari; Sakayu Shimizu
Cloning and sequencing of the ura3 and ura5 genes, and isolation and characterization of uracil auxotrophs of the fungus Mortierella alpina 1S-4.
Bioscience, biotechnology, and biochemistry 2004;68(2):277-85.
2004: Woro Triarsi Sulistyaningdyah; Jun Ogawa; Hiromi Tanaka; Chiharu Maeda; Sakayu Shimizu
Characterization of alkaliphilic laccase activity in the culture supernatant of Myrothecium verrucaria 24G-4 in comparison with bilirubin oxidase.
FEMS microbiology letters 2004;230(2):209-14.
2003: Yuji Shimada; Jun Ogawa; Yomi Watanabe; Toshihiro Nagao; Akiko Kawashima; Takashi Kobayashi; Sakayu Shimizu
Regiospecific analysis by ethanolysis of oil with immobilized Candida antarctica lipase.
Lipids 2003;38(12):1281-6.
2003: Tetsuya Kurata; Chie Kawabata-Awai; Eiji Sakuradani; Sakayu Shimizu; Kiyotaka Okada; Takuji Wada
The YORE-YORE gene regulates multiple aspects of epidermal cell differentiation in Arabidopsis.
The Plant journal : for cell and molecular biology 2003;36(1):55-66.
2003: Michihiko Kataoka; K Kita; Masaru Wada; Yoshihiko Yasohara; Junzo Hasegawa; Sakayu Shimizu
Novel bioreduction system for the production of chiral alcohols.
Applied microbiology and biotechnology 2003;62(5-6):437-45.
2003: Masataka Kajikawa; Katsuyuki T Yamato; Hiroyuki Kanamaru; Eiji Sakuradani; Sakayu Shimizu; Fukuzawa Hideya; Yasuyoshi Sakai; Kanji Ohyama
MpFAE3, a beta-ketoacyl-CoA synthase gene in the liverwort Marchantia polymorpha L., is preferentially involved in elongation of palmitic acid to stearic acid.
Bioscience, biotechnology, and biochemistry 2003;67(8):1667-74.
2003: Nobuyuki Horinouchi; Jun Ogawa; Takafumi Sakai; Takako Kawano; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Sakayu Shimizu
Construction of deoxyriboaldolase-overexpressing Escherichia coli and its application to 2-deoxyribose 5-phosphate synthesis from glucose and acetaldehyde for 2'-deoxyribonucleoside production.
Applied and environmental microbiology 2003;69(7):3791-7.
2003: Satoshi Sogabe; Ayumi Yoshizumi; Takaaki A Fukami; Yasuhiko Shiratori; Sakayu Shimizu; Hiroshi Takagi; Shigeru Nakamori; Masaru Wada
The crystal structure and stereospecificity of levodione reductase from Corynebacterium aquaticum M-13.
The Journal of biological chemistry 2003;278(21):19387-95.
2003: Norifumi Shirasaka; Shigenori Miyamoto; Tetsuo Murakami; Hajime Yoshizumi; Sakayu Shimizu
Microbial synthesis of trans isomer of eicosapentaenoic acid (EPA) from the chemically synthesized trans isomer of linolenic acid by a delta12 desaturase-defective mutant of Mortierella alpina 1S-4.
Bioscience, biotechnology, and biochemistry 2003;67(5):1164-7.
2003: Jun Ogawa; Kyota Saito; Takafumi Sakai; Nobuyuki Horinouchi; Takako Kawano; Seiichiro Matsumoto; Mie Sasaki; Yoichi Mikami; Sakayu Shimizu
Microbial production of 2-deoxyribose 5-phosphate from acetaldehyde and triosephosphate for the synthesis of 2'-deoxyribonucleosides.
Bioscience, biotechnology, and biochemistry 2003;67(4):933-6.
2003: Eiji Sakuradani; Sakayu Shimizu
Gene cloning and functional analysis of a second delta 6-fatty acid desaturase from an arachidonic acid-producing Mortierella fungus.
Bioscience, biotechnology, and biochemistry 2003;67(4):704-11.
2003: Masataka Kajikawa; Shohei Yamaoka; Katsuyuki T Yamato; Hiroyuki Kanamaru; Eiji Sakuradani; Sakayu Shimizu; Fukuzawa Hideya; Kanji Ohyama
Functional analysis of a beta-ketoacyl-CoA synthase gene, MpFAE2, by gene silencing in the liverwort Marchantia polymorpha L.
Bioscience, biotechnology, and biochemistry 2003;67(3):605-12.
2003: Masaru Wada; Ayumi Yoshizumi; Yumiko Noda; Michihiko Kataoka; Sakayu Shimizu; Hiroshi Takagi; Shigeru Nakamori
Production of a doubly chiral compound, (4R,6R)-4-hydroxy-2,2,6-trimethylcyclohexanone, by two-step enzymatic asymmetric reduction.
Applied and environmental microbiology 2003;69(2):933-7.
2003: Kohsuke Honda; Michihiko Kataoka; Eiji Sakuradani; Sakayu Shimizu
Role of Acinetobacter calcoaceticus 3,4-dihydrocoumarin hydrolase in oxidative stress defence against peroxoacids.
European journal of biochemistry / FEBS 2003;270(3):486-94.
2003: Yuzo Kojima; Michihiko Kobayashi; Sakayu Shimizu
A novel lipase from Pseudomonas fluorescens HU380: gene cloning, overproduction, renaturation-activation, two-step purification, and characterization.
Journal of bioscience and bioengineering 2003;96(3):242-9.
2003: Yuzo Kojima; Sakayu Shimizu
Purification and characterization of the lipase from Pseudomonas fluorescens HU380.
Journal of bioscience and bioengineering 2003;96(3):219-26.
2003: Hironori Omura; Masahiro Ikemoto; Michihiko Kobayashi; Sakayu Shimizu; Toyokazu Yoshida; Toru Nagasawa
Purification, characterization and gene cloning of thermostable O-acetyl-L-homoserine sulfhydrylase forming gamma-cyano-alpha-aminobutyric acid.
Journal of bioscience and bioengineering 2003;96(1):53-8.
2003: Hironori Omura; Masako Kuroda; Michihiko Kobayashi; Sakayu Shimizu; Toyokazu Yoshida; Toru Nagasawa
Purification, characterization and gene cloning of thermostable O-acetyl-L-serine sulfhydrylase forming beta-cyano-L-alanine.
Journal of bioscience and bioengineering 2003;95(5):470-5.
2003: Kohsuke Honda; Keiji Sakamoto; Shinji Kita; Michihiko Kataoka; Sakayu Shimizu
Biocatalytic deprotection of a cetraxate ester by Microbacterium sp. strain 7-1W cells.
Bioscience, biotechnology, and biochemistry 2003;67(1):192-4.
2003: Shigenobu Kishino; Jun Ogawa; Akinori Ando; Takashi Iwashita; Tsuyoshi Fujita; Hiroshi Kawashima; Sakayu Shimizu
Structural analysis of conjugated linoleic acid produced by Lactobacillus plantarum, and factors affecting isomer production.
Bioscience, biotechnology, and biochemistry 2003;67(1):179-82.
2002: Michihiko Kataoka; Atsushi Kotaka; Akiko Hasegawa; Masaru Wada; Ayumi Yoshizumi; Shigeru Nakamori; Sakayu Shimizu
Old Yellow Enzyme from Candida macedoniensis catalyzes the stereospecific reduction of the C=C bond of ketoisophorone.
Bioscience, biotechnology, and biochemistry 2002;66(12):2651-7.
2002: Jun Ogawa; Woro Triarsi Sulistyaningdyah; Hiromi Tanaka; Kenji Kano; Tokuji Ikeda; Sakayu Shimizu
Bilirubin dehydrogenase, an enzyme in Aspergillus ochraceus IB-3 useful for diagnostic measurement of bilirubin.
Bioscience, biotechnology, and biochemistry 2002;66(11):2376-81.
2002: Kohsuke Honda; Michihiko Kataoka; Sakayu Shimizu
Enzymatic preparation of D-beta-acetylthioisobutyric acid and cetraxate hydrochloride using a stereo- and/or regioselective hydrolase, 3,4-dihydrocoumarin hydrolase from Acinetobacter calcoaceticus.
Applied microbiology and biotechnology 2002;60(3):288-92.
2002: Eiji Sakuradani; N Kamada; Yuriko Hirano; M Nishihara; Hiroshi Kawashima; K Akimoto; K Higashiyama; Jun Ogawa; Sakayu Shimizu
Production of 5,8,11-eicosatrienoic acid by a delta5 and delta6 desaturation activity-enhanced mutant derived from a delta12 desaturation activity-defective mutant of Mortierella alpina 1S-4.
Applied microbiology and biotechnology 2002;60(3):281-7.
2002: Shigenobu Kishino; Jun Ogawa; Akinori Ando; Yoriko Omura; Sakayu Shimizu
Ricinoleic acid and castor oil as substrates for conjugated linoleic acid production by washed cells of Lactobacillus plantarum.
Bioscience, biotechnology, and biochemistry 2002;66(10):2283-6.
2002: Jun Ogawa; Sakayu Shimizu
Industrial microbial enzymes: their discovery by screening and use in large-scale production of useful chemicals in Japan.
Current opinion in biotechnology 2002;13(4):367-75.
2002: Yoshiteru Hashimoto; Satoshi Sasaki; Sachio Herai; Ken-Ichi Oinuma; Sakayu Shimizu; Michihiko Kobayashi
Site-directed mutagenesis for cysteine residues of cobalt-containing nitrile hydratase.
Journal of inorganic biochemistry 2002;91(1):70-7.
2002: Chee-Leong Soong; Jun Ogawa; Eiji Sakuradani; Sakayu Shimizu
Barbiturase, a novel zinc-containing amidohydrolase involved in oxidative pyrimidine metabolism.
The Journal of biological chemistry 2002;277(9):7051-8.
2002: Kohsuke Honda; Michihiko Kataoka; Hiroko Ono; Keiji Sakamoto; Shinji Kita; Sakayu Shimizu
Purification and characterization of a novel esterase promising for the production of useful compounds from Microbacterium sp. 7-1W.
FEMS microbiology letters 2002;206(2):221-7.
2001: Sakayu Shimizu; Michihiko Kataoka; Kohsuke Honda; Keiji Sakamoto
Lactone-ring-cleaving enzymes of microorganisms: their diversity and applications.
Journal of biotechnology 2001;92(2):187-94.
2001: A R Hidalgo; Muhammad Ali AKOND; K Kita; Michihiko Kataoka; Sakayu Shimizu
Isolation and primary structural analysis of two conjugated polyketone reductases from Candida parapsilosis.
Bioscience, biotechnology, and biochemistry 2001;65(12):2785-8.
2001: Qing-Shan Li; Jun Ogawa; Rolf D Schmid; Sakayu Shimizu
Engineering cytochrome P450 BM-3 for oxidation of polycyclic aromatic hydrocarbons.
Applied and environmental microbiology 2001;67(12):5735-9.
2001: Qing-Shan Li; Jun Ogawa; Rolf D Schmid; Sakayu Shimizu
Residue size at position 87 of cytochrome P450 BM-3 determines its stereoselectivity in propylbenzene and 3-chlorostyrene oxidation.
FEBS letters 2001;508(2):249-52.
2001: Michihiko Kataoka; Mie Sasaki; A R Hidalgo; M Nakano; Sakayu Shimizu
Glycolic acid production using ethylene glycol-oxidizing microorganisms.
Bioscience, biotechnology, and biochemistry 2001;65(10):2265-70.
2001: Chee-Leong Soong; Jun Ogawa; Sakayu Shimizu
Novel amidohydrolytic reactions in oxidative pyrimidine metabolism: analysis of the barbiturase reaction and discovery of a novel enzyme, ureidomalonase.
Biochemical and biophysical research communications 2001;286(1):222-6.
2001: Nobuhiro Nakano; Norifumi Shirasaka; K Masuoka; Tetsuo Murakami; T Watanabe; K Kobata; Sakayu Shimizu; Hajime Yoshizumi
Inhibitory effects of capsaicinoids on fatty acid desaturation in a rat liver cell line.
Bioscience, biotechnology, and biochemistry 2001;65(8):1859-63.
2001: Masahiko Goda; Yoshiteru Hashimoto; Sakayu Shimizu; Michihiko Kobayashi
Discovery of a novel enzyme, isonitrile hydratase, involved in nitrogen-carbon triple bond cleavage.
The Journal of biological chemistry 2001;276(26):23480-5.
2001: Noriyuki Kizaki; Yoshihiko Yasohara; Junzo Hasegawa; Masaru Wada; Michihiko Kataoka; Sakayu Shimizu
Synthesis of optically pure ethyl (S)-4-chloro-3-hydroxybutanoate by Escherichia coli transformant cells coexpressing the carbonyl reductase and glucose dehydrogenase genes.
Applied microbiology and biotechnology 2001;55(5):590-5.
2001: A Yoshisumi; Masaru Wada; Hiroshi Takagi; Sakayu Shimizu; Shigeru Nakamori
Cloning, sequence analysis, and expression in Escherichia coli of the gene encoding monovalent cation-activated levodione reductase from Corynebacterium aquaticum M-13.
Bioscience, biotechnology, and biochemistry 2001;65(4):830-6.
2001: Jun Ogawa; S Takeda; Sheng-Xue Xie; H Hatanaka; Toshihiko Ashikari; Teruo Amachi; Sakayu Shimizu
Purification, characterization, and gene cloning of purine nucleosidase from Ochrobactrum anthropi.
Applied and environmental microbiology 2001;67(4):1783-7.
2001: Jun Ogawa; K Matsumura; Shigenobu Kishino; Y Omura; Sakayu Shimizu
Conjugated linoleic acid accumulation via 10-hydroxy-12-octadecaenoic acid during microaerobic transformation of linoleic acid by Lactobacillus acidophilus.
Applied and environmental microbiology 2001;67(3):1246-52.
2001: Qing-Shan Li; Jun Ogawa; Sakayu Shimizu
Critical role of the residue size at position 87 in H2O2- dependent substrate hydroxylation activity and H2O2 inactivation of cytochrome P450BM-3.
Biochemical and biophysical research communications 2001;280(5):1258-61.
2001: H Yamada; Sakayu Shimizu; Masayuki Kobayashi
Hydratases involved in nitrile conversion: screening, characterization and application.
Chemical record (New York, N.Y.) 2001;1(2):152-61.
2000: Jun Ogawa; Chee-Leong Soong; M Ito; T Segawa; T Prana; M S Prana; Sakayu Shimizu
3-carbamoyl-alpha-picolinic acid production by imidase-catalyzed regioselective hydrolysis of 2,3-pyridinedicarboximide in a water-organic solvent, two-phase system.
Applied microbiology and biotechnology 2000;54(3):331-4.
2000: Nobuhiro Nakano; Norifumi Shirasaka; H Koyama; M Hino; Tetsuo Murakami; Sakayu Shimizu; Hajime Yoshizumi
C19 odd-chain polyunsaturated fatty acids (PUfas) are metabolized to C21-PUfas in a rat liver cell line, and curcumin, gallic acid, and their related compounds inhibit their desaturation.
Bioscience, biotechnology, and biochemistry 2000;64(8):1641-50.
2000: M Certik; Sakayu Shimizu
Kinetic analysis of oil biosynthesis by an arachidonic acid-producing fungus, Mortierella alpina 1S-4.
Applied microbiology and biotechnology 2000;54(2):224-30.
2000: Yoshihiko Yasohara; Noriyuki Kizaki; Junzo Hasegawa; Masaru Wada; Michihiko Kataoka; Sakayu Shimizu
Molecular cloning and overexpression of the gene encoding an NADPH-dependent carbonyl reductase from Candida magnoliae, involved in stereoselective reduction of ethyl 4-chloro-3-oxobutanoate.
Bioscience, biotechnology, and biochemistry 2000;64(7):1430-6.
2000: Michihiko Kataoka; J I Nomura; M Shinohara; K Nose; Keiji Sakamoto; Sakayu Shimizu
Purification and characterization of a novel lactonohydrolase from Agrobacterium tumefaciens.
Bioscience, biotechnology, and biochemistry 2000;64(6):1255-62.
2000: Chee-Leong Soong; Jun Ogawa; Sakayu Shimizu
A novel amidase (half-amidase) for half-amide hydrolysis involved in the bacterial metabolism of cyclic imides.
Applied and environmental microbiology 2000;66(5):1947-52.
2000: Masayuki Kobayashi; Sakayu Shimizu
Nitrile hydrolases.
Current opinion in chemical biology 2000;4(1):95-102.
2000: Michihiko Kataoka; Kohsuke Honda; Sakayu Shimizu
3,4-Dihydrocoumarin hydrolase with haloperoxidase activity from Acinetobacter calcoaceticus F46.
European journal of biochemistry / FEBS 2000;267(1):3-10.
1999: S Koga; Jun Ogawa; Y Choi; Sakayu Shimizu
Novel bacterial peroxidase without catalase activity from Flavobacterium meningosepticum: purification and characterization.
Biochimica et biophysica acta 1999;1435(1-2):117-26.
1999: Sheng-Xue Xie; Jun Ogawa; Sakayu Shimizu
NAD(+)-dependent (S)-specific secondary alcohol dehydrogenase involved in stereoinversion of 3-pentyn-2-ol catalyzed by Nocardia fusca AKU 2123.
Bioscience, biotechnology, and biochemistry 1999;63(10):1721-9.
1999: Eiji Sakuradani; Masayuki Kobayashi; Sakayu Shimizu
Delta6-fatty acid desaturase from an arachidonic acid-producing Mortierella fungus. Gene cloning and its heterologous expression in a fungus, Aspergillus.
Gene 1999;238(2):445-53.
1999: Sakayu Shimizu
[Pantothenic acid].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(10):2218-22.
1999: Masayuki Kobayashi; Sakayu Shimizu
[Nicotinic acid and nicotinamide].
Nihon rinsho. Japanese journal of clinical medicine 1999;57(10):2211-7.
1999: Masaru Wada; Ayumi Yoshizumi; Shigeru Nakamori; Sakayu Shimizu
Purification and characterization of monovalent cation-activated levodione reductase from Corynebacterium aquaticum M-13.
Applied and environmental microbiology 1999;65(10):4399-403.
1999: Masaru Wada; T Matsumoto; Shigeru Nakamori; M Sakamoto; Michihiko Kataoka; J Q Liu; N Itoh; H Yamada; Sakayu Shimizu
Purification and characterization of a novel enzyme, L-threo-3-hydroxyaspartate dehydratase, from Pseudomonas sp. T62.
FEMS microbiology letters 1999;179(1):147-51.
1999: Sheng-Xue Xie; Jun Ogawa; Sakayu Shimizu
Production of (R)-3-pentyn-2-ol through stereoinversion of racemic 3-pentyn-2-ol by Nocardia fusca AKU 2123.
Applied microbiology and biotechnology 1999;52(3):327-31.
1999: Eiji Sakuradani; Masayuki Kobayashi; Sakayu Shimizu
Identification of an NADH-cytochrome b(5) reductase gene from an arachidonic acid-producing fungus, Mortierella alpina 1S-4, by sequencing of the encoding cDNA and heterologous expression in a fungus, Aspergillus oryzae.
Applied and environmental microbiology 1999;65(9):3873-9.
1999: Yoshihiko Yasohara; Noriyuki Kizaki; Junzo Hasegawa; S Takahashi; Masaru Wada; Michihiko Kataoka; Sakayu Shimizu
Synthesis of optically active ethyl 4-chloro-3-hydroxybutanoate by microbial reduction.
Applied microbiology and biotechnology 1999;51(6):847-51.
1999: Masayuki Kobayashi; Eiji Sakuradani; Sakayu Shimizu
Genetic analysis of cytochrome b5 from arachidonic acid-producing fungus, Mortierella alpina 1S-4: cloning, RNA editing and expression of the gene in Escherichia coli, and purification and characterization of the gene product.
Journal of biochemistry 1999;125(6):1094-103.
1999: Eiji Sakuradani; Masayuki Kobayashi; Toshihiko Ashikari; Sakayu Shimizu
Identification of Delta12-fatty acid desaturase from arachidonic acid-producing mortierella fungus by heterologous expression in the yeast Saccharomyces cerevisiae and the fungus Aspergillus oryzae.
European journal of biochemistry / FEBS 1999;261(3):812-20.
1999: Chee-Leong Soong; Jun Ogawa; M Honda; Sakayu Shimizu
Cyclic-imide-hydrolyzing activity of D-hydantoinase from Blastobacter sp. strain A17p-4.
Applied and environmental microbiology 1999;65(4):1459-62.
1999: Nobuhiro Nakano; Norifumi Shirasaka; Tetsuo Murakami; Sakayu Shimizu; Hajime Yoshizumi
Formation of 8,11,14-octadecatrienoic acid (18:3 n-4) from naturally occurring unique fatty acid, 9,12-hexadecadienoic acid (16:2 n-4), in animal cell cultures.
Journal of nutritional science and vitaminology 1999;45(2):203-12.
1999: Michihiko Kataoka; Kenji Yamamoto; Hiroshi Kawabata; Masaru Wada; K Kita; H Yanase; Sakayu Shimizu
Stereoselective reduction of ethyl 4-chloro-3-oxobutanoate by Escherichia coli transformant cells coexpressing the aldehyde reductase and glucose dehydrogenase genes.
Applied microbiology and biotechnology 1999;51(4):486-90.
1999: Masayuki Kobayashi; Sakayu Shimizu
Cobalt proteins.
European journal of biochemistry / FEBS 1999;261(1):1-9.
1999: Masayuki Kobayashi; Makoto Goda; Sakayu Shimizu
Hydrazide synthesis: novel substrate specificity of amidase.
Biochemical and biophysical research communications 1999;256(2):415-8.
1999: Eiji Sakuradani; Masayuki Kobayashi; Sakayu Shimizu
Delta 9-fatty acid desaturase from arachidonic acid-producing fungus. Unique gene sequence and its heterologous expression in a fungus, Aspergillus.
European journal of biochemistry / FEBS 1999;260(1):208-16.
1999: M Certik; Eiji Sakuradani; M Kobayashi; Sakayu Shimizu
Characterization of the second form of NADH-cytochrome b5 reductase gene from arachidonic acid-producing fungus Mortierella alpina 1S-4.
Journal of bioscience and bioengineering 1999;88(6):667-71.
1999: Masaru Wada; Hiroshi Kawabata; Ayumi Yoshizumi; Michihiko Kataoka; Shigeru Nakamori; Yoshihiko Yasohara; Noriyuki Kizaki; J Hasegawa; Sakayu Shimizu
Occurrence of multiple ethyl 4-chloro-3-oxobutanoate-reducing enzymes in Candida magnoliae.
Journal of bioscience and bioengineering 1999;87(2):144-8.
1999: M Certik; Sakayu Shimizu
Biosynthesis and regulation of microbial polyunsaturated fatty acid production.
Journal of bioscience and bioengineering 1999;87(1):1-14.
1999: Jun Ogawa; Sakayu Shimizu
Microbial enzymes: new industrial applications from traditional screening methods.
Trends in biotechnology 1999;17(1):13-21.
1999: Masayuki Kobayashi; Sakayu Shimizu
[Nitrile hydratase and cobalt].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(1):42-50.
1999: Sakayu Shimizu; Michihiko Kataoka
Production of chiral C3- and C4-units by microbial enzymes.
Advances in biochemical engineering/biotechnology 1999;63():109-23.
1998: Masayuki Kobayashi; Makoto Goda; Sakayu Shimizu
Nitrilase catalyzes amide hydrolysis as well as nitrile hydrolysis.
Biochemical and biophysical research communications 1998;253(3):662-6.
1998: Sakayu Shimizu; Michihiko Kataoka; K Kita
Chiral alcohol synthesis with microbial carbonyl reductases in a water-organic solvent two-phase system.
Annals of the New York Academy of Sciences 1998;864():87-95.
1998: Masayuki Kobayashi; Makoto Goda; Sakayu Shimizu
The catalytic mechanism of amidase also involves nitrile hydrolysis.
FEBS letters 1998;439(3):325-8.
1998: Michihiko Kataoka; K Yamamoto; Sakayu Shimizu; M Ohta; Akiko Kita; Yoshiki Higuchi; Kunio Miki
Crystallization and preliminary X-ray diffraction study of lactonohydrolase from Fusarium oxysporum.
Acta crystallographica. Section D, Biological crystallography 1998;54(Pt 6 Pt 2):1432-4.
1998: Masayuki Kobayashi; M Shinohara; C Sakoh; Michihiko Kataoka; Sakayu Shimizu
Lactone-ring-cleaving enzyme: genetic analysis, novel RNA editing, and evolutionary implications.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(22):12787-92.
1998: Masayuki Kobayashi; Sakayu Shimizu
Metalloenzyme nitrile hydratase: structure, regulation, and application to biotechnology.
Nature biotechnology 1998;16(8):733-6.
1998: Takuma Uo; Tohru Yoshimura; Sakayu Shimizu; Nobuyoshi Esaki
Occurrence of pyridoxal 5'-phosphate-dependent serine racemase in silkworm, Bombyx mori.
Biochemical and biophysical research communications 1998;246(1):31-4.
1998: Masaru Wada; Michihiko Kataoka; Hiroshi Kawabata; Yoshihiko Yasohara; Noriyuki Kizaki; Junzo Hasegawa; Sakayu Shimizu
Purification and characterization of NADPH-dependent carbonyl reductase, involved in stereoselective reduction of ethyl 4-chloro-3-oxobutanoate, from Candida magnoliae.
Bioscience, biotechnology, and biochemistry 1998;62(2):280-5.
1998: Michihiko Kataoka; L P Sri Rohani; Masaru Wada; K Kita; H Yanase; I Urabe; Sakayu Shimizu
Escherichia coli transformant expressing the glucose dehydrogenase gene from Bacillus megaterium as a cofactor regenerator in a chiral alcohol production system.
Bioscience, biotechnology, and biochemistry 1998;62(1):167-9.
1998: Chee-Leong Soong; Jun Ogawa; H Sukiman; T Prana; M Sri Prana; Sakayu Shimizu
Distribution of cyclic imide-transforming activity in microorganisms.
FEMS microbiology letters 1998;158(1):51-5.
1997: Michihiko Kataoka; L P Rohani; Kenji Yamamoto; Masaru Wada; Hiroshi Kawabata; K Kita; H Yanase; Sakayu Shimizu
Enzymatic production of ethyl (R)-4-chloro-3-hydroxybutanoate: asymmetric reduction of ethyl 4-chloro-3-oxobutanoate by an Escherichia coli transformant expressing the aldehyde reductase gene from yeast.
Applied microbiology and biotechnology 1997;48(6):699-703.
1997: Masayuki Kobayashi; Y Fujiwara; Makoto Goda; Hidetsugu Komeda; Sakayu Shimizu
Identification of active sites in amidase: evolutionary relationship between amide bond- and peptide bond-cleaving enzymes.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(22):11986-91.
1997: Michihiko Kataoka; M Ikemi; T Morikawa; T Miyoshi; K Nishi; M Wada; H Yamada; Sakayu Shimizu
Isolation and characterization of D-threonine aldolase, a pyridoxal-5'-phosphate-dependent enzyme from Arthrobacter sp. DK-38.
European journal of biochemistry / FEBS 1997;248(2):385-93.
1997: N Shirasaka; K Nishi; Sakayu Shimizu
Biosynthesis of furan fatty acids (F-acids) by a marine bacterium, Shewanella putrefaciens.
Biochimica et biophysica acta 1997;1346(3):253-60.
1997: Michihiko Kataoka; Masaru Wada; K Nishi; H Yamada; Sakayu Shimizu
Purification and characterization of L-allo-threonine aldolase from Aeromonas jandaei DK-39.
FEMS microbiology letters 1997;151(2):245-8.
1997: Jun Ogawa; Chee-Leong Soong; M Honda; Sakayu Shimizu
Imidase, a dihydropyrimidinase-like enzyme involved in the metabolism of cyclic imides.
European journal of biochemistry / FEBS 1997;243(1-2):322-7.
1997: Hidetsugu Komeda; Masayuki Kobayashi; Sakayu Shimizu
A novel transporter involved in cobalt uptake.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(1):36-41.
1997: Sakayu Shimizu; Jun Ogawa; Michihiko Kataoka; Masayuki Kobayashi
Screening of novel microbial enzymes for the production of biologically and chemically useful compounds.
Advances in biochemical engineering/biotechnology 1997;58():45-87.
1996: Sakayu Shimizu; Michihiko Kataoka
Optical resolution of pantolactone by a novel fungal enzyme, lactonohydrolase.
Annals of the New York Academy of Sciences 1996;799():650-8.
1996: H Kawashima; K Akimoto; S Jareonkitmongkol; N Shirasaka; Sakayu Shimizu
Nicardipine and nifedipine inhibit fatty acid desaturases in rat liver microsomes.
Bioscience, biotechnology, and biochemistry 1996;60(10):1672-6.
1996: Hidetsugu Komeda; Y Hori; Masayuki Kobayashi; Sakayu Shimizu
Transcriptional regulation of the Rhodococcus rhodochrous J1 nitA gene encoding a nitrilase.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(20):10572-7.
1996: Hidetsugu Komeda; Masayuki Kobayashi; Sakayu Shimizu
A novel gene cluster including the Rhodococcus rhodochrous J1 nhlBA genes encoding a low molecular mass nitrile hydratase (L-NHase) induced by its reaction product.
The Journal of biological chemistry 1996;271(26):15796-802.
1996: Hidetsugu Komeda; Masayuki Kobayashi; Sakayu Shimizu
Characterization of the gene cluster of high-molecular-mass nitrile hydratase (H-NHase) induced by its reaction product in Rhodococcus rhodochrous J1.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(9):4267-72.
1996: Michihiko Kataoka; K Yamamoto; Sakayu Shimizu; K Kita; T Hashimoto; H Yanase; Akiko Kita; Kunio Miki
Crystallization and preliminary X-ray diffraction study of aldehyde reductase from a red yeast, Sporobolomyces salmonicolor.
Acta crystallographica. Section D, Biological crystallography 1996;52(Pt 2):405-6.
1996: H Kawashima; K Akimoto; N Shirasaka; Sakayu Shimizu
Inhibitory effects of alkyl gallate and its derivatives on fatty acid desaturation.
Biochimica et biophysica acta 1996;1299(1):34-8.
1996: H Kawashima; K Akimoto; S Jareonkitmongkol; N Shirasaka; Sakayu Shimizu
Inhibition of rat liver microsomal desaturases by curcumin and related compounds.
Bioscience, biotechnology, and biochemistry 1996;60(1):108-10.
1995: Jun Ogawa; W Nirdnoy; M Tabata; H Yamada; Sakayu Shimizu
A new enzymatic method for the measurement of creatinine involving a novel ATP-dependent enzyme, N-methylhydantoin amidohydrolase.
Bioscience, biotechnology, and biochemistry 1995;59(12):2292-4.
1995: Jun Ogawa; H Miyake; Sakayu Shimizu
Purification and characterization of N-carbamoyl-L-amino acid amidohydrolase with broad substrate specificity from Alcaligenes xylosoxidans.
Applied microbiology and biotechnology 1995;43(6):1039-43.
1995: Jun Ogawa; Sakayu Shimizu
Purification and characterization of dihydroorotase from Pseudomonas putida.
Archives of microbiology 1995;164(5):353-7.
1995: N Shirasaka; K Nishi; Sakayu Shimizu
Occurrence of a furan fatty acid in marine bacteria.
Biochimica et biophysica acta 1995;1258(3):225-7.
1995: N Kouzaki; H Kawashima; M C Chung; Sakayu Shimizu
Purification and characterization of two forms of cytochrome b5 from an arachidonic acid-producing fungus, Mortierella hygrophila.
Biochimica et biophysica acta 1995;1256(3):319-26.
1995: Jun Ogawa; J M Kim; W Nirdnoy; Y Amano; H Yamada; Sakayu Shimizu
Purification and characterization of an ATP-dependent amidohydrolase, N-methylhydantoin amidohydrolase, from Pseudomonas putida 77.
European journal of biochemistry / FEBS 1995;229(1):284-90.
1995: Masayuki Kobayashi; T Suzuki; T Fujita; M Masuda; Sakayu Shimizu
Occurrence of enzymes involved in biosynthesis of indole-3-acetic acid from indole-3-acetonitrile in plant-associated bacteria, Agrobacterium and Rhizobium.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(3):714-8.
1994: Jun Ogawa; M C Chung; S Hida; H Yamada; Sakayu Shimizu
Thermostable N-carbamoyl-D-amino acid amidohydrolase: screening, purification and characterization.
Journal of biotechnology 1994;38(1):11-9.
1994: Jun Ogawa; Sakayu Shimizu
Beta-ureidopropionase with N-carbamoyl-alpha-L-amino acid amidohydrolase activity from an aerobic bacterium, Pseudomonas putida IFO 12996.
European journal of biochemistry / FEBS 1994;223(2):625-30.
1994: Jun Ogawa; Sakayu Shimizu; H Yamada
Enzymatic asymmetric synthesis of alpha-methyl arylalkylamines and alpha-methyl arylalkylalcohols by arylalkyl acylamidases.
Bioorganic & medicinal chemistry 1994;2(6):429-32.
1993: S Jareonkitmongkol; Eiji Sakuradani; Sakayu Shimizu
A Novel Delta5-Desaturase-Defective Mutant of Mortierella alpina 1S-4 and Its Dihomo-gamma-Linolenic Acid Productivity.
Applied and environmental microbiology 1993;59(12):4300-4.
1993: Masayuki Kobayashi; Hidetsugu Komeda; T Nagasawa; Makoto Nishiyama; Sueharu Horinouchi; T Beppu; H Yamada; Sakayu Shimizu
Amidase coupled with low-molecular-mass nitrile hydratase from Rhodococcus rhodochrous J1. Sequencing and expression of the gene and purification and characterization of the gene product.
European journal of biochemistry / FEBS 1993;217(1):327-36.
1993: S Jareonkitmongkol; Sakayu Shimizu; H Yamada
Occurrence of two nonmethylene-interrupted delta 5 polyunsaturated fatty acids in a delta 6-desaturase-defective mutant of the fungus Mortierella alpina 1S-4.
Biochimica et biophysica acta 1993;1167(2):137-41.
1993: Jun Ogawa; Sakayu Shimizu; H Yamada
N-carbamoyl-D-amino acid amidohydrolase from Comamonas sp. E222c purification and characterization.
European journal of biochemistry / FEBS 1993;212(3):685-91.
1992: Sakayu Shimizu; Michihiko Kataoka; Kazuyuki Shimizu; M Hirakata; Kimitoshi Sakamoto; H Yamada
Purification and characterization of a novel lactonohydrolase, catalyzing the hydrolysis of aldonate lactones and aromatic lactones, from Fusarium oxysporum.
European journal of biochemistry / FEBS 1992;209(1):383-90.
1992: Sakayu Shimizu; Jun Ogawa; M C Chung; H Yamada
Purification and characterization of a novel enzyme, arylalkyl acylamidase, from Pseudomonas putida Sc2.
European journal of biochemistry / FEBS 1992;209(1):375-82.
1992: Michihiko Kataoka; H Sakai; T Morikawa; M Katoh; T Miyoshi; Sakayu Shimizu; H Yamada
Characterization of aldehyde reductase of Sporobolomyces salmonicolor.
Biochimica et biophysica acta 1992;1122(1):57-62.
1992: S Jareonkitmongkol; Hiroshi Kawashima; N Shirasaka; Sakayu Shimizu; Hirofumi Yamada
Production of Dihomo-gamma-Linolenic Acid by a Delta5-Desaturase-Defective Mutant of Mortierella alpina 1S-4.
Applied and environmental microbiology 1992;58(7):2196-200.
1992: Sakayu Shimizu; S Jareonkitmongkol; H Kawashima; K Akimoto; H Yamada
Inhibitory effect of curcumin on fatty acid desaturation in Mortierella alpina 1S-4 and rat liver microsomes.
Lipids 1992;27(7):509-12.
1992: Michihiko Kataoka; Y Doi; T S Sim; Sakayu Shimizu; H Yamada
A novel NADPH-dependent carbonyl reductase of Candida macedoniensis: purification and characterization.
Archives of biochemistry and biophysics 1992;294(2):469-74.
1992: Michihiko Kataoka; Sakayu Shimizu; H Yamada
Purification and characterization of a novel FMN-dependent enzyme. Membrane-bound L-(+)-pantoyl lactone dehydrogenase from Nocardia asteroides.
European journal of biochemistry / FEBS 1992;204(2):799-806.
1992: Michihiko Kataoka; Sakayu Shimizu; H Yamada
Distribution and immunological characterization of microbial aldehyde reductases.
Archives of microbiology 1992;157(3):279-83.
1992: H Yamada; Sakayu Shimizu; Y Shinmen; K Akimoto; H Kawashima
Production of polyunsaturated fatty acids by microorganisms.
Journal of nutritional science and vitaminology 1992;Spec No():255-8.
1991: Sakayu Shimizu; K Akimoto; Y Shinmen; H Kawashima; M Sugano; H Yamada
Sesamin is a potent and specific inhibitor of delta 5 desaturase in polyunsaturated fatty acid biosynthesis.
Lipids 1991;26(7):512-6.
1990: Michihiko Kataoka; Sakayu Shimizu; Y Doi; Hirofumi Yamada
Stereospecific reduction of ethyl 2' -ketopantothenate to ethyl d-(+)-pantothenate with microbial cells as a catalyst.
Applied and environmental microbiology 1990;56(11):3595-7.
1989: Sakayu Shimizu; J M Kim; H Yamada
Microbial enzymes for creatinine assay: a review.
Clinica chimica acta; international journal of clinical chemistry 1989;185(3):241-52.
1989: H Hata; Sakayu Shimizu; S Hattori; H Yamada
Ketopantoyl lactone reductase is a conjugated polyketone reductase.
FEMS microbiology letters 1989;49(1):87-90.
1989: H Hata; Sakayu Shimizu; S Hattori; H Yamada
Ketopantoyl-lactone reductase from Candida parapsilosis: purification and characterization as a conjugated polyketone reductase.
Biochimica et biophysica acta 1989;990(2):175-81.
1988: Sakayu Shimizu; Michihiko Kataoka; M C Chung; H Yamada
Ketopantoic acid reductase of Pseudomonas maltophilia 845. Purification, characterization, and role in pantothenate biosynthesis.
The Journal of biological chemistry 1988;263(24):12077-84.
1988: Sakayu Shimizu; S Hattori; H Hata; H Yamada
A novel fungal enzyme, NADPH-dependent carbonyl reductase, showing high specificity to conjugated polyketones. Purification and characterization.
European journal of biochemistry / FEBS 1988;174(1):37-44.
1988: Sakayu Shimizu; Y Shinmen; H Kawashima; K Akimoto; H Yamada
Fungal mycelia as a novel source of eicosapentaenoic acid. Activation of enzyme(s) involved in eicosapentaenoic acid production at low temperature.
Biochemical and biophysical research communications 1988;150(1):335-41.
1988: Sakayu Shimizu; H Yamada
Enzymatic process for the production of pharmacologically useful nucleosides.
Annals of the New York Academy of Sciences 1988;542():423-7.
1987: Sakayu Shimizu; S Hattori; H Hata; Hirofumi Yamada
One-Step Microbial Conversion of a Racemic Mixture of Pantoyl Lactone to Optically Active d-(-)-Pantoyl Lactone.
Applied and environmental microbiology 1987;53(3):519-22.
1984: Sakayu Shimizu; A Esumi; R Komaki; Hirofumi Yamada
Production of Coenzyme A by a Mutant of Brevibacterium ammoniagenes Resistant to Oxypantetheine.
Applied and environmental microbiology 1984;48(6):1118-22.