Preview
Sign-in for full Details 
Sign-in free and Explore the Exciting World of BiomedExperts:
- Over 1.500.000 Profiles
- More than 1.800 Organizations worldwide
- State of the Art Network Visualizations
- Manage your own Profile
- Locate Experts in your Country/Region
- Locate Experts in your 1. and 2. Level Network
- Connect to Experts Worldwide
NetworkView
Kunitada Shimotohno
This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers
together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles
free of charge to researchers worldwide.
Research Profile (preview)
Living Beings
Physiology
Anatomy
Chemicals & Drugs
Genes & Molecular Sequences
Disorders
Sign-in to see full Profile
Network (preview)
41
Hijikata, Makoto
19
Watashi, Koichi
10
Ariumi, Yasuo
10
Chiba, Tsutomu
9
Marusawa, Hiroyuki
9
Ohshima, Takayuki
8
Hishiki, Takayuki
6
Dansako, Hiromichi
6
Kato, Nobuyuki
6
Murata, Takayuki
6
Takaku, Hiroshi
5
Tsuchihara, Katsuya
5
Yamada, Osamu
5
Zhang, Jing
5
Aly, Hussein
Sign-in to see all Coauthors
Publications
Sign-in to see all Publications
Sign in free and see...
Visualized networks:
See your personal network in
sophisticated graphical views
GeoTargeted Searches:
Locate experts around the world
and connect with global collaborators
Research Profiles:
See the visualized research activity
of experts around the globe
Sign-in to see more
Geonetwork of Kunitada Shimotohno (preview)
Cities where this author has publications
Cities where co-authors of this author have publications
Sign-in to see more
All Publications
-
2009: Goto Kaku; Watashi Koichi; Inoue Daisuke; Hijikata Makoto; Shimotohno Kunitada
Identification of cellular and viral factors related to anti-hepatitis C virus activity of cyclophilin inhibitor.
Cancer science 2009;100(10):1943-50.
-
2009: Aly Hussein Hassan; Qi Yue; Atsuzawa Kimie; Usuda Nobuteru; Takada Yasutsugu; Mizokami Masashi; Shimotohno Kunitada; Hijikata Makoto
Strain-dependent viral dynamics and virus-cell interactions in a novel in vitro system supporting the life cycle of blood-borne hepatitis C virus.
Hepatology (Baltimore, Md.) 2009;50(3):689-96.
-
2009: Sugiyama Kazuo; Suzuki Kenji; Nakazawa Takahide; Funami Kenji; Hishiki Takayuki; Ogawa Kazuya; Saito Satoru; Shimotohno Kumiko W; Suzuki Takeshi; Shimizu Yuko; Tobita Reiri; Hijikata Makoto; Takaku Hiroshi; Shimotohno Kunitada
Genetic analysis of hepatitis C virus with defective genome and its infectivity in vitro.
Journal of virology 2009;83(13):6922-8.
-
2009: Murata Takayuki; Sato Yoshitaka; Nakayama Sanae; Kudoh Ayumi; Iwahori Satoko; Isomura Hiroki; Tajima Masako; Hishiki Takayuki; Ohshima Takayuki; Hijikata Makoto; Shimotohno Kunitada; Tsurumi Tatsuya
TORC2, a coactivator of cAMP-response element-binding protein, promotes Epstein-Barr virus reactivation from latency through interaction with viral BZLF1 protein.
The Journal of biological chemistry 2009;284(12):8033-41.
-
2009: Ujino Saneyuki; Yamaguchi Saori; Shimotohno Kunitada; Takaku Hiroshi
Heat-shock protein 90 is essential for stabilization of the hepatitis C virus nonstructural protein NS3.
The Journal of biological chemistry 2009;284(11):6841-6.
-
2009: Murakami Yoshiki; Aly Hussein H; Tajima Atsushi; Inoue Ituro; Shimotohno Kunitada
Regulation of the hepatitis C virus genome replication by miR-199a.
Journal of hepatology 2009;50(3):453-60.
-
2009: Aly Hussein Hassan; Shimotohno Kunitada; Hijikata Makoto
3D cultured immortalized human hepatocytes useful to develop drugs for blood-borne HCV.
Biochemical and biophysical research communications 2009;379(2):330-4.
-
2009: Okamoto Mika; Sakai Masashi; Goto Yukinori; Salim Mohammed Ta; Baba Chiaki; Goto Kaku; Watashi Koichi; Shimotohno Kunitada; Baba Masanori
Anti-bovine viral diarrhoea virus and hepatitis C virus activity of the cyclooxygenase inhibitor SC-560.
Antiviral chemistry & chemotherapy 2009;20(1):47-54.
-
2009: Ikejiri Masahiro; Ohshima Takayuki; Fukushima Akemi; Shimotohno Kunitada; Maruyama Tokumi
Synthesis and anti-HCV activity of 2',5'-deoxy-5'-phenacyladenosine analogs.
Nucleic acids symposium series (2004) 2009;(53):103-4.
-
2009: Ogawa Kazuya; Hishiki Takayuki; Shimizu Yuko; Funami Kenji; Sugiyama Kazuo; Miyanari Yusuke; Shimotohno Kunitada
Hepatitis C virus utilizes lipid droplet for production of infectious virus.
Proceedings of the Japan Academy. Series B, Physical and biological sciences 2009;85(7):217-28.
-
2008: Isono Osamu; Ohshima Takayuki; Saeki Yasushi; Matsumoto Jun; Hijikata Makoto; Tanaka Keiji; Shimotohno Kunitada
Human T-cell leukemia virus type 1 HBZ protein bypasses the targeting function of ubiquitination.
The Journal of biological chemistry 2008;283(49):34273-82.
-
2008: Zhang Jing; Yamada Osamu; Kawagishi Kenji; Araki Hiromasa; Yamaoka Shoji; Hattori Toshio; Shimotohno Kunitada
Human T-cell leukemia virus type 1 Tax modulates interferon-alpha signal transduction through competitive usage of the coactivator CBP/p300.
Virology 2008;379(2):306-13.
-
2008: Ikejiri Masahiro; Ohshima Takayuki; Fukushima Akemi; Shimotohno Kunitada; Maruyama Tokumi
Synthesis and evaluation of 5'-modified 2'-deoxyadenosine analogues as anti-hepatitis C virus agents.
Bioorganic & medicinal chemistry letters 2008;18(16):4638-41.
-
2008: Arimoto Kei-ichiro; Shimotohno Kunitada
Regulation of viral recognition signaling by ubiquitin modification.
Uirusu. Journal of virology 2008;58(1):47-54.
-
2008: Noguchi Tohru; Otsubaki Tomoko; Ando Izuru; Ogura Naoki; Ikeda Satoru; Shimotohno Kunitada
Isolation and gene analysis of interferon alpha-resistant cell clones of the hepatitis C virus subgenome.
Virology 2008;375(2):424-32.
-
2008: Miyanari Yusuke; Usuda Nobuteru; Shimotohno Kunitada
[Strategy of HCV proliferation]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2008;53(5):666-72.
-
2008: Nakamura Mitsuyasu; Saito Hidetsugu; Ikeda Masanori; Tada Shinichiro; Kumagai Naoki; Kato Nobuyuki; Shimotohno Kunitada; Hibi Toshifumi
Possible molecular mechanism of the relationship between NS5B polymorphisms and early clearance of hepatitis C virus during interferon plus ribavirin treatment.
Journal of medical virology 2008;80(4):632-9.
-
2008: Iwai A; Hijikata M; Hishiki T; Isono O; Chiba T; Shimotohno K
Coiled-coil domain containing 85B suppresses the beta-catenin activity in a p53-dependent manner.
Oncogene 2008;27(11):1520-6.
-
2008: Arimoto Kei-Ichiro; Konishi Hideyuki; Shimotohno Kunitada
UbcH8 regulates ubiquitin and ISG15 conjugation to RIG-I.
Molecular immunology 2008;45(4):1078-84.
-
2007: Zhang Jing; Yamada Osamu; Kawagishi Kenji; Yoshida Hiroshi; Araki Hiromasa; Yamaoka Shoji; Hattori Toshio; Shimotohno Kunitada
Up-regulation of hepatitis C virus replication by human T cell leukemia virus type I-encoded Tax protein.
Virology 2007;369(1):198-205.
-
2007: Ikejiri Masahiro; Ohshima Takayuki; Kato Keizo; Toyama Masaaki; Murata Takayuki; Shimotohno Kunitada; Maruyama Tokumi
5'-O-masked 2'-deoxyadenosine analogues as lead compounds for hepatitis C virus (HCV) therapeutic agents.
Bioorganic & medicinal chemistry 2007;15(22):6882-92.
-
2007: Watashi Koichi; Inoue Daisuke; Hijikata Makoto; Goto Kaku; Aly Hussein H; Shimotohno Kunitada
Anti-hepatitis C virus activity of tamoxifen reveals the functional association of estrogen receptor with viral RNA polymerase NS5B.
The Journal of biological chemistry 2007;282(45):32765-72.
-
2007: Miyanari Yusuke; Atsuzawa Kimie; Usuda Nobuteru; Watashi Koichi; Hishiki Takayuki; Zayas Margarita; Bartenschlager Ralf; Wakita Takaji; Hijikata Makoto; Shimotohno Kunitada
The lipid droplet is an important organelle for hepatitis C virus production.
Nature cell biology 2007;9(9):1089-97.
-
2007: Hishiki Takayuki; Ohshima Takayuki; Ego Takeshi; Shimotohno Kunitada
BCL3 acts as a negative regulator of transcription from the human T-cell leukemia virus type 1 long terminal repeat through interactions with TORC3.
The Journal of biological chemistry 2007;282(39):28335-43.
-
2007: Endo Y; Marusawa H; Kinoshita K; Morisawa T; Sakurai T; Okazaki I-M; Watashi K; Shimotohno K; Honjo T; Chiba T
Expression of activation-induced cytidine deaminase in human hepatocytes via NF-kappaB signaling.
Oncogene 2007;26(38):5587-95.
-
2007: Watashi Koichi; Shimotohno Kunitada
Chemical genetics approach to hepatitis C virus replication: cyclophilin as a target for anti-hepatitis C virus strategy.
Reviews in medical virology 2007;17(4):245-52.
-
2007: Arimoto Kei-ichiro; Takahashi Hitoshi; Hishiki Takayuki; Konishi Hideyuki; Fujita Takashi; Shimotohno Kunitada
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7500-5.
-
2007: Takao Yukari; Yamada Akira; Yutani Shigeru; Takedatsu Hiroko; Ono Takeharu; Etoh Kojyu; Wang Yi; Suzuki Susumu; Ide Tatsuya; Shimotohno Kunitada; Sata Michio; Itoh Kyogo
Identification of new immunogenic peptides in conserved regions of hepatitis C virus (HCV) 1b with the potentiality to generate cytotoxic T lymphocytes in HCV1b(+) HLA-A24(+) patients.
Hepatology research : the official journal of the Japan Society of Hepatology 2007;37(3):186-95.
-
2007: Ishida Takeshi; Iwai Akio; Hijikata Makoto; Shimotohno Kunitada
The expression of phosphatidic acid phosphatase 2a, which hydrolyzes lipids to generate diacylglycerol, is regulated by p73, a member of the p53 family.
Biochemical and biophysical research communications 2007;353(1):74-9.
-
2007: Aly Hussein H; Watashi Koichi; Hijikata Makoto; Kaneko Hiroyasu; Takada Yasutugu; Egawa Hiroto; Uemoto Shinji; Shimotohno Kunitada
Serum-derived hepatitis C virus infectivity in interferon regulatory factor-7-suppressed human primary hepatocytes.
Journal of hepatology 2007;46(1):26-36.
-
2007: Zhang Jing; Yamada Osamu; Yoshida Hiroshi; Sakamoto Takashi; Araki Hiromasa; Shimotohno Kunitada
Helper virus-independent trans-replication of hepatitis C virus-derived minigenome.
Biochemical and biophysical research communications 2007;352(1):170-6.
-
2007: Suzuki Hitoshi; Kaneko Hiroyasu; Tamai Nobushige; Shimotohno Kunitada; Miyano-Kurosaki Naoko; Takaku Hiroshi
Suppression of hepatitis C virus core protein by short hairpin RNA expression vectors in the core protein expression Huh-7 cells.
Nucleosides, nucleotides & nucleic acids 2007;26(6-7):815-20.
-
2007: Ikejiri Masahiro; Ohshima Takayuki; Kato Keizo; Toyama Masaaki; Murata Takayuki; Shimotohno Kunitada; Maruyama Tokumi
Suppression of subgenomic hepatitis C virus replication by 5'-O-masked analogues of 6-chloropurine-2'-deoxyriboside.
Nucleic acids symposium series (2004) 2007;(51):439-40.
-
2007: El-Farrash Mohamed A; Aly Hussein H; Watashi Koichi; Hijikata Makoto; Egawa Hiroto; Shimotohno Kunitada
In vitro infection of immortalized primary hepatocytes by HCV genotype 4a and inhibition of virus replication by cyclosporin.
Microbiology and immunology 2007;51(1):127-33.
-
2006: Komohara Yoshihiro; Yano Hirohisa; Shichijo Shigeki; Shimotohno Kunitada; Itoh Kyogo; Yamada Akira
High expression of APOBEC3G in patients infected with hepatitis C virus.
Journal of molecular histology 2006;37(8-9):327-32.
-
2006: Tsumura Akiko; Hayakawa Tomohiro; Kumaki Yuichi; Takebayashi Shin-ichiro; Sakaue Morito; Matsuoka Chisa; Shimotohno Kunitada; Ishikawa Fuyuki; Li En; Ueda Hiroki R; Nakayama Jun-ichi; Okano Masaki
Maintenance of self-renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b.
Genes to cells : devoted to molecular & cellular mechanisms 2006;11(7):805-14.
-
2006: Murata Takayuki; Shimotohno Kunitada
Ubiquitination and proteasome-dependent degradation of human eukaryotic translation initiation factor 4E.
The Journal of biological chemistry 2006;281(30):20788-800.
-
2006: Ishii Naoto; Watashi Koichi; Hishiki Takayuki; Goto Kaku; Inoue Daisuke; Hijikata Makoto; Wakita Takaji; Kato Nobuyuki; Shimotohno Kunitada
Diverse effects of cyclosporine on hepatitis C virus strain replication.
Journal of virology 2006;80(9):4510-20.
-
2006: Hamazaki Hiroyuki; Ujino Saneyuki; Miyano-Kurosaki Naoko; Shimotohno Kunitada; Takaku Hiroshi
Inhibition of hepatitis C virus RNA replication by short hairpin RNA synthesized by T7 RNA polymerase in hepatitis C virus subgenomic replicons.
Biochemical and biophysical research communications 2006;343(3):988-94.
-
2006: Goto Kaku; Watashi Koichi; Murata Takayuki; Hishiki Takayuki; Hijikata Makoto; Shimotohno Kunitada
Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811.
Biochemical and biophysical research communications 2006;343(3):879-84.
-
2006: Naka Kazuhito; Abe Ken-ichi; Takemoto Kazunori; Dansako Hiromichi; Ikeda Masanori; Shimotohno Kunitada; Kato Nobuyuki
Epigenetic silencing of interferon-inducible genes is implicated in interferon resistance of hepatitis C virus replicon-harboring cells.
Journal of hepatology 2006;44(5):869-78.
-
2006: Shimakami Tetsuro; Honda Masao; Kusakawa Takashi; Murata Takayuki; Shimotohno Kunitada; Kaneko Shuichi; Murakami Seishi
Effect of hepatitis C virus (HCV) NS5B-nucleolin interaction on HCV replication with HCV subgenomic replicon.
Journal of virology 2006;80(7):3332-40.
-
2006: Murakami Y; Yasuda T; Saigo K; Urashima T; Toyoda H; Okanoue T; Shimotohno K
Comprehensive analysis of microRNA expression patterns in hepatocellular carcinoma and non-tumorous tissues.
Oncogene 2006;25(17):2537-45.
-
2006: Hamazaki Hiroyuki; Takahashi Hitoshi; Shimotohno Kunitada; Miyano-Kurosaki Naoko; Takaku Hiroshi
Inhibition of hcv replication in HCV replicon by shRNAs.
Nucleosides, nucleotides & nucleic acids 2006;25(7):801-5.
-
2005: Zhang Jing; Yamada Osamu; Sakamoto Takashi; Yoshida Hiroshi; Araki Hiromasa; Murata Takayuki; Shimotohno Kunitada
Inhibition of hepatitis C virus replication by pol III-directed overexpression of RNA decoys corresponding to stem-loop structures in the NS5B coding region.
Virology 2005;342(2):276-85.
-
2005: Naka Kazuhito; Takemoto Kazunori; Abe Ken-ichi; Dansako Hiromichi; Ikeda Masanori; Shimotohno Kunitada; Kato Nobuyuki
Interferon resistance of hepatitis C virus replicon-harbouring cells is caused by functional disruption of type I interferon receptors.
The Journal of general virology 2005;86(Pt 10):2787-92.
-
2005: Kaida Atsushi; Ariumi Yasuo; Baba Keiko; Matsubae Masami; Takao Toshifumi; Shimotohno Kunitada
Identification of a novel p300-specific-associating protein, PRS1 (phosphoribosylpyrophosphate synthetase subunit 1).
The Biochemical journal 2005;391(Pt 2):239-47.
-
2005: Murata Takayuki; Hijikata Makoto; Shimotohno Kunitada
Enhancement of internal ribosome entry site-mediated translation and replication of hepatitis C virus by PD98059.
Virology 2005;340(1):105-15.
-
2005: Watashi Koichi; Ishii Naoto; Hijikata Makoto; Inoue Daisuke; Murata Takayuki; Miyanari Yusuke; Shimotohno Kunitada
Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase.
Molecular cell 2005;19(1):111-22.
-
2005: Watashi Koichi; Shimotohno Kunitada
[Current approaches for developing new anti-HCV agents and analyses of HCV replication using anti-HCV agents]
Uirusu. Journal of virology 2005;55(1):105-10.
-
2005: Zhang Jing; Yamada Osamu; Sakamoto Takashi; Yoshida Hiroshi; Araki Hiromasa; Shimotohno Kunitada
Exploiting cis-acting replication elements to direct hepatitis C virus-dependent transgene expression.
Journal of virology 2005;79(10):5923-32.
-
2005: Obata Yoko; Yamamoto Kazuo; Miyazaki Masanobu; Shimotohno Kunitada; Kohno Shigeru; Matsuyama Toshifumi
Role of cyclophilin B in activation of interferon regulatory factor-3.
The Journal of biological chemistry 2005;280(18):18355-60.
-
2005: Koyanagi Michiyo; Hijikata Makoto; Watashi Koichi; Masui Osamu; Shimotohno Kunitada
Centrosomal P4.1-associated protein is a new member of transcriptional coactivators for nuclear factor-kappaB.
The Journal of biological chemistry 2005;280(13):12430-7.
-
2005: Takahashi Hitoshi; Yamaji Masashi; Hosaka Masahiro; Kishine Hiroe; Hijikata Makoto; Shimotohno Kunitada
Analysis of the 5' end structure of HCV subgenomic RNA replicated in a Huh7 cell line.
Intervirology 2005;48(2-3):104-11.
-
2005: Kato Nobuyuki; Nakamura Takashi; Dansako Hiromichi; Namba Katsuyuki; Abe Ken-ichi; Nozaki Akito; Naka Kazuhito; Ikeda Masanori; Shimotohno Kunitada
Genetic variation and dynamics of hepatitis C virus replicons in long-term cell culture.
The Journal of general virology 2005;86(Pt 3):645-56.
-
2005: Ego Takeshi; Tanaka Yuetsu; Shimotohno Kunitada
Interaction of HTLV-1 Tax and methyl-CpG-binding domain 2 positively regulates the gene expression from the hypermethylated LTR.
Oncogene 2005;24(11):1914-23.
-
2005: Akita Kazumasa; Kawata Sanae; Shimotohno Kunitada
p21WAF1 modulates NF-kappaB signaling and induces anti-apoptotic protein Bcl-2 in Tax-expressing rat fibroblast.
Virology 2005;332(1):249-57.
-
2005: Matsumoto Jun; Ohshima Takayuki; Isono Osamu; Shimotohno Kunitada
HTLV-1 HBZ suppresses AP-1 activity by impairing both the DNA-binding ability and the stability of c-Jun protein.
Oncogene 2005;24(6):1001-10.
-
2005: Murata Takayuki; Ohshima Takayuki; Yamaji Masashi; Hosaka Masahiro; Miyanari Yusuke; Hijikata Makoto; Shimotohno Kunitada
Suppression of hepatitis C virus replicon by TGF-beta.
Virology 2005;331(2):407-17.
-
2005: Abe Ken-ichi; Ikeda Masanori; Dansako Hiromichi; Naka Kazuhito; Shimotohno Kunitada; Kato Nobuyuki
cDNA microarray analysis to compare HCV subgenomic replicon cells with their cured cells.
Virus research 2005;107(1):73-81.
-
2005: Suzuki Hitoshi; Kaneko Hiroyasu; Tamai Nobushige; Miyano-Kurosaki Naoko; Hashimoto Kahoko; Shimotohno Kunitada; Takaku Hiroshi
Suppression of HCV RNA replication by baculovirus-mediated shRNA expression.
Nucleic acids symposium series (2004) 2005;(49):339-40.
-
2005: Sudo Kenji; Yamaji Kayo; Kawamura Kouich; Nishijima Tomoko; Kojima Naoko; Aibe Kazuhiko; Shimotohno Kunitada; Shimizu Yasuaki
High-throughput screening of low molecular weight NS3-NS4A protease inhibitors using a fluorescence resonance energy transfer substrate.
Antiviral chemistry & chemotherapy 2005;16(6):385-92.
-
2004: Kodama Yuzo; Hijikata Makoto; Kageyama Ryoichiro; Shimotohno Kunitada; Chiba Tsutomu
The role of notch signaling in the development of intrahepatic bile ducts.
Gastroenterology 2004;127(6):1775-86.
-
2004: Koga Hiroshi; Ohshima Takayuki; Shimotohno Kunitada
Enhanced activation of tax-dependent transcription of human T-cell leukemia virus type I (HTLV-I) long terminal repeat by TORC3.
The Journal of biological chemistry 2004;279(51):52978-83.
-
2004: Namba Katsuyuki; Naka Kazuhito; Dansako Hiromichi; Nozaki Akito; Ikeda Masanori; Shiratori Yasushi; Shimotohno Kunitada; Kato Nobuyuki
Establishment of hepatitis C virus replicon cell lines possessing interferon-resistant phenotype.
Biochemical and biophysical research communications 2004;323(1):299-309.
-
2004: Iwai Akio; Marusawa Hiroyuki; Matsuzawa Shu-ichi; Fukushima Toru; Hijikata Makoto; Reed John C; Shimotohno Kunitada; Chiba Tsutomu
Siah-1L, a novel transcript variant belonging to the human Siah family of proteins, regulates beta-catenin activity in a p53-dependent manner.
Oncogene 2004;23(45):7593-600.
-
2004: Lin Jye-Yee; Ohshima Takayuki; Shimotohno Kunitada
Association of Ubc9, an E2 ligase for SUMO conjugation, with p53 is regulated by phosphorylation of p53.
FEBS letters 2004;573(1-3):15-8.
-
2004: Hijikata Makoto; Shimotohno Kunitada
[Processing of HCV precursor polyprotein]
Nippon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 7(Pt 1):54-8.
-
2004: Kato Nobuyuki; Shimotohno Kunitada
[Gene organization of hepatitis C virus and its sequence diversity]
Nippon rinsho. Japanese journal of clinical medicine 2004;62 Suppl 7(Pt 1):26-31.
-
2004: Ohshima Takayuki; Koga Hiroshi; Shimotohno Kunitada
Transcriptional activity of peroxisome proliferator-activated receptor gamma is modulated by SUMO-1 modification.
The Journal of biological chemistry 2004;279(28):29551-7.
-
2004: Zhang Jing; Yamada Osamu; Sakamoto Takashi; Yoshida Hiroshi; Iwai Takahiro; Matsushita Yoshihisa; Shimamura Hideo; Araki Hiromasa; Shimotohno Kunitada
Down-regulation of viral replication by adenoviral-mediated expression of siRNA against cellular cofactors for hepatitis C virus.
Virology 2004;320(1):135-43.
-
2004: Shimakami Tetsuro; Hijikata Makoto; Luo Hong; Ma Yuan Yuan; Kaneko Shuichi; Shimotohno Kunitada; Murakami Seishi
Effect of interaction between hepatitis C virus NS5A and NS5B on hepatitis C virus RNA replication with the hepatitis C virus replicon.
Journal of virology 2004;78(6):2738-48.
-
2004: Hamazaki Hiroyuki; Ujino Saneyuki; Abe Emi; Miyano-Kurosaki Naoko; Shimotohno Kunitada; Takaku Hiroshi
RNAi expression mediated inhibition of HCV replication.
Nucleic acids symposium series (2004) 2004;(48):307-8.
-
2003: Ohshima Takayuki; Shimotohno Kunitada
Transforming growth factor-beta-mediated signaling via the p38 MAP kinase pathway activates Smad-dependent transcription through SUMO-1 modification of Smad4.
The Journal of biological chemistry 2003;278(51):50833-42.
-
2003: Miyanari Yusuke; Hijikata Makoto; Yamaji Masashi; Hosaka Masahiro; Takahashi Hitoshi; Shimotohno Kunitada
Hepatitis C virus non-structural proteins in the probable membranous compartment function in viral genome replication.
The Journal of biological chemistry 2003;278(50):50301-8.
-
2003: Watashi Koichi; Shimotohno Kunitada
The roles of hepatitis C virus proteins in modulation of cellular functions: a novel action mechanism of the HCV core protein on gene regulation by nuclear hormone receptors.
Cancer science 2003;94(11):937-43.
-
2003: Watashi Koichi; Hijikata Makoto; Hosaka Masahiro; Yamaji Masashi; Shimotohno Kunitada
Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes.
Hepatology (Baltimore, Md.) 2003;38(5):1282-8.
-
2003: Watashi Koichi; Hijikata Makoto; Tagawa Ayako; Doi Takahiro; Marusawa Hiroyuki; Shimotohno Kunitada
Modulation of retinoid signaling by a cytoplasmic viral protein via sequestration of Sp110b, a potent transcriptional corepressor of retinoic acid receptor, from the nucleus.
Molecular and cellular biology 2003;23(21):7498-509.
-
2003: Youn Hwang-Geum; Matsumoto Jun; Tanaka Yuetsu; Shimotohno Kunitada
SR-related protein TAXREB803/SRL300 is an important cellular factor for the transactivational function of human T-cell lymphotropic virus type 1 Tax.
Journal of virology 2003;77(18):10015-27.
-
2003: Kato Nobuyuki; Sugiyama Kazuo; Namba Katsuyuki; Dansako Hiromichi; Nakamura Takashi; Takami Marika; Naka Kazuhito; Nozaki Akito; Shimotohno Kunitada
Establishment of a hepatitis C virus subgenomic replicon derived from human hepatocytes infected in vitro.
Biochemical and biophysical research communications 2003;306(3):756-66.
-
2003: Kawata Sanae; Ariumi Yasuo; Shimotohno Kunitada
p21(Waf1/Cip1/Sdi1) prevents apoptosis as well as stimulates growth in cells transformed or immortalized by human T-cell leukemia virus type 1-encoded tax.
Journal of virology 2003;77(13):7291-9.
-
2003: Shimotohno Kunitada
[How can we improve the system to analyze HCV replication system?]
Uirusu. Journal of virology 2003;53(1):87-91.
-
2003: Matsuda Akio; Suzuki Yutaka; Honda Goichi; Muramatsu Shuji; Matsuzaki Osamu; Nagano Yukiko; Doi Takahiro; Shimotohno Kunitada; Harada Takeshi; Nishida Eisuke; Hayashi Hiroshi; Sugano Sumio
Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways.
Oncogene 2003;22(21):3307-18.
-
2003: Ariumi Yasuo; Ego Takeshi; Kaida Atsushi; Matsumoto Mikiko; Pandolfi Pier Paolo; Shimotohno Kunitada
Distinct nuclear body components, PML and SMRT, regulate the trans-acting function of HTLV-1 Tax oncoprotein.
Oncogene 2003;22(11):1611-9.
-
2002: Omori Akira; Ichinose Sachiyo; Kitajima Satoko; Shimotohno Kumiko W; Murashima Yoshiya L; Shimotohno Kunitada; Seto-Ohshima Akiko
Gerbils of a seizure-sensitive strain have a mitochondrial inner membrane protein with different isoelectric points from those of a seizure-resistant strain.
Electrophoresis 2002;23(24):4167-74.
-
2002: Omori Akira; Ichinose Sachiyo; Kitajima Satoko; Shimotohno Kumiko W; Murashima Yoshiya L; Shimotohno Kunitada; Seto-Ohshima Akiko
Gerbils of a seizure-sensitive strain have a mitochondrial inner membrane protein with different isoelectric points from those of a seizure-resistant strain.
Electrophoresis 2002;23(24):4167-74.
-
2002: Ego Takeshi; Ariumi Yasuo; Shimotohno Kunitada
The interaction of HTLV-1 Tax with HDAC1 negatively regulates the viral gene expression.
Oncogene 2002;21(47):7241-6.
-
2002: Ueda Yoshihide; Hijikata Makoto; Takagi Shinji; Takada Ritsuko; Takada Shinji; Chiba Tsutomu; Shimotohno Kunitada
Wnt/beta-catenin signaling suppresses apoptosis in low serum medium and induces morphologic change in rodent fibroblasts.
International journal of cancer. Journal international du cancer 2002;99(5):681-8.
-
2002: Kishine Hiroe; Sugiyama Kazuo; Hijikata Makoto; Kato Nobuyuki; Takahashi Hitoshi; Noshi Takeshi; Nio Yasunori; Hosaka Masahiro; Miyanari Yusuke; Shimotohno Kunitada
Subgenomic replicon derived from a cell line infected with the hepatitis C virus.
Biochemical and biophysical research communications 2002;293(3):993-9.
-
2002: Masui Osamu; Ueda Yoshihide; Tsumura Akiko; Koyanagi Michiyo; Hijikata Makoto; Shimotohno Kunitada
RelA suppresses the Wnt/beta-catenin pathway without exerting trans-acting transcriptional ability.
International journal of molecular medicine 2002;9(5):489-93.
-
2002: Shimotohno Kunitada; Watashi Koichi; Tsuchihara Katsuya; Fukuda Katsuhiko; Marusawa Hiroyuki; Hijikata Makoto
Hepatitis C virus and its roles in cell proliferation.
Journal of gastroenterology 2002;37 Suppl 13():50-4.
-
2001: Takagi S; Ueda Y; Hijikata M; Shimotohno K
Overproduced p73alpha activates a minimal promoter through a mechanism independent of its transcriptional activity.
FEBS letters 2001;509(1):47-52.
-
2001: Ariumi Y; Kaida A; Hatanaka M; Shimotohno K
Functional cross-talk of HIV-1 Tat with p53 through its C-terminal domain.
Biochemical and biophysical research communications 2001;287(2):556-61.
-
2001: Watashi K; Hijikata M; Marusawa H; Doi T; Shimotohno K
Cytoplasmic localization is important for transcription factor nuclear factor-kappa B activation by hepatitis C virus core protein through its amino terminal region.
Virology 2001;286(2):391-402.
-
2001: Ueda Y; Hijikata M; Takagi S; Chiba T; Shimotohno K
Transcriptional activities of p73 splicing variants are regulated by inter-variant association.
The Biochemical journal 2001;356(Pt 3):859-66.
-
2001: Ueda Y; Hijikata M; Takagi S; Takada R; Takada S; Chiba T; Shimotohno K
p73beta, a variant of p73, enhances Wnt/beta-catenin signaling in Saos-2 cells.
Biochemical and biophysical research communications 2001;283(2):327-33.
-
2001: Fukuda K; Tsuchihara K; Hijikata M; Nishiguchi S; Kuroki T; Shimotohno K
Hepatitis C virus core protein enhances the activation of the transcription factor, Elk1, in response to mitogenic stimuli.
Hepatology (Baltimore, Md.) 2001;33(1):159-65.
-
2001: Marusawa H; Hijikata M; Watashi K; Chiba T; Shimotohno K
Regulation of Fas-mediated apoptosis by NF-kappaB activity in human hepatocyte derived cell lines.
Microbiology and immunology 2001;45(6):483-9.
-
2000: Shimotohno K
Hepatitis C virus and its pathogenesis.
Seminars in cancer biology 2000;10(3):233-40.
-
2000: Ariumi Y; Kaida A; Lin J Y; Hirota M; Masui O; Yamaoka S; Taya Y; Shimotohno K
HTLV-1 tax oncoprotein represses the p53-mediated trans-activation function through coactivator CBP sequestration.
Oncogene 2000;19(12):1491-9.
-
2000: Kaida A; Ariumi Y; Ueda Y; Lin J Y; Hijikata M; Ikawa S; Shimotohno K
Functional impairment of p73 and p51, the p53-related proteins, by the human T-cell leukemia virus type 1 Tax oncoprotein.
Oncogene 2000;19(6):827-30.
-
2000: Marusawa H; Uemoto S; Hijikata M; Ueda Y; Tanaka K; Shimotohno K; Chiba T
Latent hepatitis B virus infection in healthy individuals with antibodies to hepatitis B core antigen.
Hepatology (Baltimore, Md.) 2000;31(2):488-95.
-
1999: Ueda Y; Hijikata M; Takagi S; Chiba T; Shimotohno K
New p73 variants with altered C-terminal structures have varied transcriptional activities.
Oncogene 1999;18(35):4993-8.
-
1999: Hijikata M; Tsuchihara K; Marusawa H; Shimotohno K
[Regulation of cell proliferation by hepatitis C virus]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1999;44(11):1543-51.
-
1999: Ariumi Y; Masutani M; Copeland T D; Mimori T; Sugimura T; Shimotohno K; Ueda K; Hatanaka M; Noda M
Suppression of the poly(ADP-ribose) polymerase activity by DNA-dependent protein kinase in vitro.
Oncogene 1999;18(32):4616-25.
-
1999: Marusawa H; Hijikata M; Chiba T; Shimotohno K
Hepatitis C virus core protein inhibits Fas- and tumor necrosis factor alpha-mediated apoptosis via NF-kappaB activation.
Journal of virology 1999;73(6):4713-20.
-
1999: Tsuchihara K; Hijikata M; Fukuda K; Kuroki T; Yamamoto N; Shimotohno K
Hepatitis C virus core protein regulates cell growth and signal transduction pathway transmitting growth stimuli.
Virology 1999;258(1):100-7.
-
1999: Hirota M; Satoh S; Asabe S; Kohara M; Tsukiyama-Kohara K; Kato N; Hijikata M; Shimotohno K
Phosphorylation of nonstructural 5A protein of hepatitis C virus: HCV group-specific hyperphosphorylation.
Virology 1999;257(1):130-7.
-
1998: Ariumi Y; Ueda K; Masutani M; Copeland T D; Noda M; Hatanaka M; Shimotohno K
In vivo phosphorylation of poly(ADP-ribose) polymerase is independent of its activation.
FEBS letters 1998;436(2):288-92.
-
1998: Inoue H; Sakashita H; Shimizu Y; Yamaji K; Yokota T; Sudo K; Shigeta S; Shimotohno K
Expression of a hepatitis C virus NS3 protease-NS4A fusion protein in Escherichia coli.
Biochemical and biophysical research communications 1998;245(2):478-82.
-
1998: Ariumi Y; Shimotohno K; Noda M; Hatanaka M
Characterization of the internal promoter of human T-cell leukemia virus type I.
FEBS letters 1998;423(1):25-30.
-
1997: Tsuchihara K; Tanaka T; Hijikata M; Kuge S; Toyoda H; Nomoto A; Yamamoto N; Shimotohno K
Specific interaction of polypyrimidine tract-binding protein with the extreme 3'-terminal structure of the hepatitis C virus genome, the 3'X.
Journal of virology 1997;71(9):6720-6.
Sign-in to see more
