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Hwa-Sup Shin

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Eun-Seok Park; Hwa-Sup Shin; Hwan-Soo Yoo; Kyu-Dong Yoo; Jin-Tae Hong; Shin-Il Kang; Bokyung Kim; Mi-Yea Lee; Yeo-Pyo Yun
Camptothecin inhibits platelet-derived growth factor-BB-induced proliferation of rat aortic vascular smooth muscle cells through inhibition of PI3K/Akt signaling pathway.
Eun-Seok Park; Jong Seok Park; Kyu Yang Yi; Hun-Jong Chung; Zhong-Ping Feng; Yong Chang Jang; Do-Hyun Kang; Jun Chul Kang; Bokyung Kim; Hwa-Sup Shin
5-AIQ inhibits H2O2-induced apoptosis through reactive oxygen species scavenging and Akt/GSK-3β signaling pathway in H9c2 cardiomyocytes.
Kwokyin Hui; Hwa-Sup Shin; Hong-Shuo Sun; Michelle Arnot; Zhong-Ping Feng
Differential regulation of low and high voltage-activated calcium channels in neonatal rat myocytes following chronic PKA modulation.

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All Publications

2013: Eun-Seok Park; Hwa-Sup Shin; Hwan-Soo Yoo; Kyu-Dong Yoo; Jin-Tae Hong; Shin-Il Kang; Bokyung Kim; Mi-Yea Lee; Yeo-Pyo Yun
Camptothecin inhibits platelet-derived growth factor-BB-induced proliferation of rat aortic vascular smooth muscle cells through inhibition of PI3K/Akt signaling pathway.
Experimental cell research 2013;319(7):982-91.
2013: Eun-Seok Park; Jong Seok Park; Kyu Yang Yi; Hun-Jong Chung; Zhong-Ping Feng; Yong Chang Jang; Do-Hyun Kang; Jun Chul Kang; Bokyung Kim; Hwa-Sup Shin
5-AIQ inhibits H2O2-induced apoptosis through reactive oxygen species scavenging and Akt/GSK-3β signaling pathway in H9c2 cardiomyocytes.
Toxicology and applied pharmacology 2013;268(1):90-8.
2011: Kwokyin Hui; Hwa-Sup Shin; Hong-Shuo Sun; Michelle Arnot; Zhong-Ping Feng
Differential regulation of low and high voltage-activated calcium channels in neonatal rat myocytes following chronic PKA modulation.
Channels (Austin, Tex.) 2011;5(4):357-66.
2011: Na Young Ko; Se Hwan Mun; Seung Hyun Lee; Jie Wan Kim; Do Kyun Kim; Hyuk Soon Kim; Erk Her; Soo Hyun Kim; Hyung Sik Won; Hwa-Sup Shin; Hyung Sik Kim; Young Mi Kim; Wahn Soo Choi
Interleukin-32α production is regulated by MyD88-dependent and independent pathways in IL-1β-stimulated human alveolar epithelial cells.
Immunobiology 2011;216(1-2):32-40.
2010: In-Sang Jung; Sung-Hun Lee; Min-Kyu Yang; Jung-Woo Park; Kyu Yang Yi; Sung-Eun Yoo; Suk-Hyung Kwon; Hun-Jong Chung; Wahn Soo Choi; Hwa-Sup Shin
Cardioprotective effects of the novel Na+/H+ exchanger-1 inhibitor KR-32560 in a perfused rat heart model of global ischemia and reperfusion: Involvement of the Akt-GSK-3beta cell survival pathway and antioxidant enzyme.
Archives of pharmacal research 2010;33(8):1241-51.
2009: Se Hwan Mun; Hyuk Soon Kim; Jie Wan Kim; Na Young Ko; Do Kyun Kim; Beob-Yi Lee; Bokyung Kim; Hyung Sik Won; Hwa-Sup Shin; Jeung-Whan Han; Hoi Young Lee; Young Mi Kim; Wahn Soo Choi
Oral administration of curcumin suppresses production of matrix metalloproteinase (MMP)-1 and MMP-3 to ameliorate collagen-induced arthritis: inhibition of the PKCdelta/JNK/c-Jun pathway.
Journal of pharmacological sciences 2009;111(1):13-21.
2009: Min-Kyu Yang; Sung-Hun Lee; Ho-Won Seo; Kyu Yang Yi; Sung-Eun Yoo; Byung Ho Lee; Hun-Jong Chung; Hyung-Sik Won; Chang-Soo Lee; Suk-Hyung Kwon; Wahn Soo Choi; Hwa-Sup Shin
KR-31761, a novel K+(ATP)-channel opener, exerts cardioprotective effects by opening both mitochondrial K+(ATP) and Sarcolemmal K+(ATP) channels in rat models of ischemia/reperfusion-induced heart injury.
Journal of pharmacological sciences 2009;109(2):222-32.
2008: Jun Ho Lee; Jie Wan Kim; Na Young Ko; Se Hwan Mun; Do Kyun Kim; Ju Dong Kim; Hyung Sik Won; Hwa-Sup Shin; Hyung Sik Kim; Erk Her; Young Mi Kim; Wahn Soo Choi
Mast cell-mediated allergic response is suppressed by Sophorae flos: inhibition of SRC-family kinase.
Experimental biology and medicine (Maywood, N.J.) 2008;233(10):1271-9.
2008: Sung-Hun Lee; Min-Kyu Yang; Jong-Hyun Lim; Ho-Won Seo; Kyu Yang Yi; Sung-Eun Yoo; Byung Ho Lee; Hyung-Sik Won; Chang-Soo Lee; Wahn Soo Choi; Hwa-Sup Shin
KR-31762, a novel KATP channel opener, exerts cardioprotective effects by opening SarcKATP channels in rat models of ischemia/reperfusion-induced heart injury.
Archives of pharmacal research 2008;31(4):482-9.
2008: Jung-Woo Park; Sung-Hun Lee; Min-Kyu Yang; Jung-Jin Lee; Min-Jin Song; Si-Yong Ryu; Hun-Jong Chung; Hyung-Sik Won; Chang-Soo Lee; Suk-Hyung Kwon; Yeo-Pyo Yun; Wahn Soo Choi; Hwa-Sup Shin
15,16-dihydrotanshinone I, a major component from Salvia miltiorrhiza Bunge (Dansham), inhibits rabbit platelet aggregation by suppressing intracellular calcium mobilization.
Archives of pharmacal research 2008;31(1):47-53.
2007: Hwan Myung Lee; Hyo Jin Kim; Hyo-Jun Park; Kyung-Jong Won; Junghwan Kim; Hwa-Sup Shin; Pyo-Jam Park; Hyun-Jun Kim; Kyung-Yung Lee; Seung Hwa Park; Chang-Kwon Lee; Bokyung Kim
Spleen tyrosine kinase participates in Src-mediated migration and proliferation by PDGF-BB in rat aortic smooth muscle cells.
Archives of pharmacal research 2007;30(6):761-9.
2007: Ju-Han Lee; In-Sang Jung; Sung-Hun Lee; Min-Kyu Yang; Ji-Hye Hwang; Hak-Dong Lee; Yu-Sun Cho; Min-Jin Song; Kyu Yang Yi; Sung-Eun Yoo; Suk-Hyung Kwon; Bokyung Kim; Chang-Soo Lee; Hwa-Sup Shin
Cardioprotective effects of BMS-180448, a prototype mitoK(ATP) channel opener, and the role of salvage kinases, in the rat model of global ischemia and reperfusion heart injury.
Archives of pharmacal research 2007;30(5):634-40.
2007: Tack-Joong Kim; Jinseon Jeon; Yongri Jin; Dong Ju Son; Hwan-Soo Yoo; Jin Tae Hong; Chung-Kyu Ryu; Hwa-Sup Shin; Kwang-Ho Lee; Yeo-Pyo Yun
Effects of KTJ740, a novel antithrombotic agent, on platelet-derived growth factor-induced rat aortic smooth muscle cell proliferation and cell cycle progression.
Journal of cardiovascular pharmacology 2007;49(5):280-6.
2007: Jung-Jin Lee; Yongri Jin; Yong Lim; Ji-Yeon Yu; Tack-Joong Kim; Hwan-Soo Yoo; Hwa-Sup Shin; Yeo-Pyo Yun
Oleanolic acid, a pentacyclic triterpenoid, induces rabbit platelet aggregation through a phospholipase C-calcium dependent signaling pathway.
Archives of pharmacal research 2007;30(2):210-4.
2006: Chang-Kwon Lee; Junghwan Kim; Kyung-Jong Won; Hwan Myung Lee; Hyo Jin Kim; Hui Yul Roh; Hyo-Jun Park; Hwa-Sup Shin; Tae-Kyu Park; Bokyung Kim; Sang-Mok Lee
Phorbol ester-induced contraction through p38 mitogen-activated protein kinase is diminished in aortas from DOCA-salt hypertensive rats.
Archives of pharmacal research 2006;29(11):1024-31.
2006: Kyung-Sup Lee; Jung-Woo Park; Yongri Jin; In-Sang Jung; Mi-Ra Cho; Kyu Yang Yi; Sung-Eun Yoo; Hun-Jong Chung; Yeo-Pyo Yun; Tae-Kyu Park; Hwa-Sup Shin
Antiplatelet activity of [5-(2-methoxy-5-chlorophenyl)furan-2-ylcarbonyl]guanidine (KR-32570), a novel sodium/hydrogen exchanger-1 and its mechanism of action.
Archives of pharmacal research 2006;29(5):375-83.
2006: Kyung-Sup Lee; Yongri Jin; Jung-Jin Lee; Yong Lim; Dong Ju Son; Chong-Kil Lee; Kyu Yang Yi; Sung-Eun Yoo; Hwa-Sup Shin; Yeo-Pyo Yun
Anti-platelet activity of KR-32560, a novel sodium/hydrogen exchanger-1 inhibitor.
Pharmacological research : the official journal of the Italian Pharmacological Society 2006;53(3):265-70.
2005: Hui Yul Roh; In-Sang Jung; Jung-Woo Park; Yeo-Pyo Yun; Kyu Yang Yi; Sung-Eun Yoo; Suk-Hyung Kwon; Hun-Jong Chung; Hwa-Sup Shin
Cardioprotective effects of [5-(2-methyl-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32568) in an anesthetized rat model of ischemia and reperfusion heart injury.
Pharmacology 2005;75(1):37-44.
2005: Jung-Woo Park; Hui Yul Roh; In-Sang Jung; Yeo-Pyo Yun; Kyu Yang Yi; Sung-Eun Yoo; Suk-Hyung Kwon; Hun-Jong Chung; Hwa-Sup Shin
Effects of [5-(2-methoxy-5-fluorophenyl)furan-2-ylcarbonyl]guanidine (KR-32560), a novel sodium/hydrogen exchanger-1 inhibitor, on myocardial infarct size and ventricular arrhythmias in a rat model of ischemia/reperfusion heart injury.
Journal of pharmacological sciences 2005;98(4):439-49.
2005: Mi-Ra Cho; Jung-Woo Park; In-Sang Jung; Kyu Yang Yi; Sung-Eun Yoo; Hun-Jong Chung; Yeo-Pyo Yun; Suk-Hyung Kwon; Hwa-Sup Shin
BMS-191095, a cardioselective mitochondrial K(ATP) opener, inhibits human platelet aggregation by opening mitochondrial K(ATP) channels.
Archives of pharmacal research 2005;28(1):61-7.
2003: Yang-Su Park; Sung-Eun Yoo; Hwa-Sup Shin; Yongri Jin; Yeo-Pyo Yun
Pharmacological characterization of vasorelaxant effects of BMS-180448, a novel cardioselective ATP-sensitive potassium channel opener, in rat aorta.
Journal of pharmacological sciences 2003;92(3):218-27.
2002: Byung Ho Lee; Sung-Eun Yoo; Hwa-Sup Shin
Effects of SK-1080 on intimal thickening and impaired vascular relaxation after balloon injury in rats.
Pharmacology 2002;66(2):81-8.
1999: Byung Ho Lee; S H Lee; Y S Jung; Ho Won Seo; Sung-Eun Yoo; Hwa-Sup Shin
Pharmacological characterization of KR-30988, a novel non-peptide AT1 receptor antagonist, in rat, rabbit and dog.
The Journal of pharmacy and pharmacology 1999;51(10):1191-200.
1999: Byung Ho Lee; Ho Won Seo; K J Kwon; Sung-Eun Yoo; Hwa-Sup Shin
In vivo pharmacologic profile of SK-1080, an orally active nonpeptide AT1-receptor antagonist.
Journal of cardiovascular pharmacology 1999;33(3):375-82.
1999: S H Lee; Y S Jung; Byung Ho Lee; S I Yun; Sung-Eun Yoo; Hwa-Sup Shin
Characterization of angiotensin II antagonism displayed by SK-1080, a novel nonpeptide AT1-receptor antagonist.
Journal of cardiovascular pharmacology 1999;33(3):367-74.
1998: Y S Jung; TS Cho; C H Moon; Hwa-Sup Shin
Capsaicin-induced desensitization is prevented by capsazepine but not by ruthenium red in guinea pig bronchi.
European journal of pharmacology 1998;362(2-3):193-8.
1998: Hwa-Sup Shin; Ho Won Seo; J H Oh; Byung Ho Lee
Antihypertensive effects of the novel potassium channel activator SKP-450 and its major metabolites in rats.
Arzneimittel-Forschung 1998;48(10):969-78.
1998: Hwa-Sup Shin; Ho Won Seo; Sung-Eun Yoo; Byung Ho Lee
Cardiovascular pharmacology of SKP-450, a new potassium channel activator, and its major metabolites SKP-818 and SKP-310.
Pharmacology 1998;56(3):111-24.
1998: Y S Jung; C H Moon; TS Cho; Sung-Eun Yoo; Hwa-Sup Shin
Cardioprotective effects of KR-30450, a novel K+(ATP) opener, and its major metabolite KR-30818 on isolated rat hearts.
Japanese journal of pharmacology 1998;76(1):65-73.
1998: Byung Ho Lee; Sung-Eun Yoo; Hwa-Sup Shin
Hemodynamic profile of SKP-450, a new potassium-channel activator.
Journal of cardiovascular pharmacology 1998;31(1):85-94.
1997: Byung Ho Lee; Hwa-Sup Shin
Interaction of nitric oxide and renin angiotensin system in pulmonary arterial circulation of RHR.
Archives of pharmacal research 1997;20(5):389-95.
1997: Byung Ho Lee; Hwa-Sup Shin
Interaction of nitric oxide and the renin angiotensin system in renal hypertensive rats.
Japanese journal of pharmacology 1997;74(1):83-90.