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Dean Shinabarger

Research Profile

Chemicals & Drugs

Anatomy

Ribosomes

Living Beings

Co-author Network

Publications

TOP 3
Michelle M Butler; Diane M Citron; Sofya Dvoskin; Hanping Feng; Ciarán P Kelly; Dean L Shinabarger; Saul Tzipori; George E Wright; Terry L Bowlin
MBX-500, a hybrid antibiotic with in vitro and in vivo efficacy against toxigenic Clostridium difficile.
Michelle M Butler; John D Williams; Norton P Peet; Donald T Moir; Rekha G Panchal; Sina Bavari; Dean L Shinabarger; Terry L Bowlin
Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates.
Fred C Tenover; Portia P Williams; Sheila Stocker; Angela Thompson; Leigh Ann Clark; Brandi Limbago; Roberta B Carey; Susan M Poppe; Dean L Shinabarger; John E McGowan
Accuracy of six antimicrobial susceptibility methods for testing linezolid against staphylococci and enterococci.

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All Publications

2012: Michelle M Butler; Diane M Citron; Sofya Dvoskin; Hanping Feng; Ciarán P Kelly; Dean L Shinabarger; Saul Tzipori; George E Wright; Terry L Bowlin
MBX-500, a hybrid antibiotic with in vitro and in vivo efficacy against toxigenic Clostridium difficile.
Antimicrobial agents and chemotherapy 2012;56(9):4786-92.
2010: Michelle M Butler; John D Williams; Norton P Peet; Donald T Moir; Rekha G Panchal; Sina Bavari; Dean L Shinabarger; Terry L Bowlin
Comparative in vitro activity profiles of novel bis-indole antibacterials against gram-positive and gram-negative clinical isolates.
Antimicrobial agents and chemotherapy 2010;54(9):3974-7.
2007: Fred C Tenover; Portia P Williams; Sheila Stocker; Angela Thompson; Leigh Ann Clark; Brandi Limbago; Roberta B Carey; Susan M Poppe; Dean L Shinabarger; John E McGowan
Accuracy of six antimicrobial susceptibility methods for testing linezolid against staphylococci and enterococci.
Journal of clinical microbiology 2007;45(9):2917-22.
2007: Karen L Leach; Steven M Swaney; Jerry R Colca; William G McDonald; James R Blinn; Lisa M Thomasco; Robert C Gadwood; Dean L Shinabarger; Liqun Xiong; Alexander S Mankin
The site of action of oxazolidinone antibiotics in living bacteria and in human mitochondria.
Molecular cell 2007;26(3):393-402.
2006: Steven M Swaney; Mark McCroskey; Dean L Shinabarger; Zhigang Wang; Benjamin A Turner; Christian N Parker
Characterization of a high-throughput screening assay for inhibitors of elongation factor p and ribosomal peptidyl transferase activity.
Journal of biomolecular screening 2006;11(7):736-42.
2005: Jianhua Xu; Ashkan Golshani; Hiroyuki Aoki; Jaanus Remme; John Chosay; Dean L Shinabarger; M Clelia Ganoza
Protected nucleotide G2608 in 23S rRNA confers resistance to oxazolidinones in E. coli.
Biochemical and biophysical research communications 2005;328(2):471-6.
2003: Jerry R Colca; William G McDonald; Daniel J Waldon; Lisa M Thomasco; Robert C Gadwood; Eric T Lund; Gregory S Cavey; William Mathews; Lonnie D Adams; Eric T Cecil; James D Pearson; Jeffrey H Bock; John E Mott; Dean L Shinabarger; Liqun Xiong; Alexander S Mankin
Cross-linking in the living cell locates the site of action of oxazolidinone antibiotics.
The Journal of biological chemistry 2003;278(24):21972-9.
2002: Norbert Polacek; Steven M Swaney; Dean L Shinabarger; Alexander S Mankin
SPARK--a novel method to monitor ribosomal peptidyl transferase activity.
Biochemistry 2002;41(39):11602-10.
2002: Hiroyuki Aoki; Lizhu Ke; Susan M Poppe; Toni-Jo Poel; Elizabeth A Weaver; Robert C Gadwood; Richard C Thomas; Dean L Shinabarger; M Clelia Ganoza
Oxazolidinone antibiotics target the P site on Escherichia coli ribosomes.
Antimicrobial agents and chemotherapy 2002;46(4):1080-5.
2002: Casey Chun Zhou; Steven M Swaney; Dean L Shinabarger; Brian J Stockman
1H nuclear magnetic resonance study of oxazolidinone binding to bacterial ribosomes.
Antimicrobial agents and chemotherapy 2002;46(3):625-9.
2001: J Prystowsky; F Siddiqui; John Chosay; Dean L Shinabarger; John J Millichap; Lance R Peterson; Gary A Noskin
Resistance to linezolid: characterization of mutations in rRNA and comparison of their occurrences in vancomycin-resistant enterococci.
Antimicrobial agents and chemotherapy 2001;45(7):2154-6.
2000: Liqun Xiong; PS Kloss; Stephen Douthwaite; Niels Møller Andersen; Steven M Swaney; Dean L Shinabarger; Alexander S Mankin
Oxazolidinone resistance mutations in 23S rRNA of Escherichia coli reveal the central region of domain V as the primary site of drug action.
Journal of bacteriology 2000;182(19):5325-31.
1999: PS Kloss; Liqun Xiong; Dean L Shinabarger; Alexander S Mankin
Resistance mutations in 23 S rRNA identify the site of action of the protein synthesis inhibitor linezolid in the ribosomal peptidyl transferase center.
Journal of molecular biology 1999;294(1):93-101.
1998: Steven M Swaney; Hiroyuki Aoki; M Clelia Ganoza; Dean L Shinabarger
The oxazolidinone linezolid inhibits initiation of protein synthesis in bacteria.
Antimicrobial agents and chemotherapy 1998;42(12):3251-5.
1997: Dean L Shinabarger; Keith Marotti; RW Murray; Alice H Lin; Earline P Melchior; Steven M Swaney; D S Dunyak; W F Demyan; J M Buysse
Mechanism of action of oxazolidinones: effects of linezolid and eperezolid on translation reactions.
Antimicrobial agents and chemotherapy 1997;41(10):2132-6.