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Hubert Blum

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Jan B Kuhlmann; Hubert E Blum
Locoregional therapy for cholangiocarcinoma.
Sibylle J Rau; Robert Thimme; Takaji Wakita; Hubert E Blum; Eberhard Hildt; Kiyoshi Himmelsbach; Richard Fischer
CD40 inhibits replication of hepatitis C virus in primary human hepatocytes by c-Jun N terminal kinase activation independent from the interferon pathway.
Dominik Bettinger; Hubert E Blum; Eva Knüppel; Robert Thimme; Michael Schultheiss; Hans Christian Spangenberg
Diarrhea predicts a positive response to sorafenib in patients with advanced hepatocellular carcinoma.

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2013: Jan B Kuhlmann; Hubert E Blum
Locoregional therapy for cholangiocarcinoma.
Current opinion in gastroenterology 2013;29(3):324-8.
2013: Sibylle J Rau; Robert Thimme; Takaji Wakita; Hubert E Blum; Eberhard Hildt; Kiyoshi Himmelsbach; Richard Fischer
CD40 inhibits replication of hepatitis C virus in primary human hepatocytes by c-Jun N terminal kinase activation independent from the interferon pathway.
Hepatology (Baltimore, Md.) 2013;57(1):23-36.
2012: Dominik Bettinger; Hubert E Blum; Eva Knüppel; Robert Thimme; Michael Schultheiss; Hans Christian Spangenberg
Diarrhea predicts a positive response to sorafenib in patients with advanced hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2012;56(2):789-90.
2012: Juandy Jo; Lars Joeckel; Volker Lohmann; Sibylle J Rau; Cathy Royer; Karine Sá Ferreira; Julia Schmidt; Bianca Seigel; Peter Aichele; Ulrike Aichele; Thomas F Baumert; Bertram Bengsch; Emmanuel Bisse; Hubert E Blum; Christoph Borner; Richard Fischer; Robert Thimme
Low perforin expression of early differentiated HCV-specific CD8+ T cells limits their hepatotoxic potential.
Journal of hepatology 2012;57(1):9-16.
2012: Christoph Neumann-Haefelin; Hubert E Blum; Robert Thimme
[Direct antiviral treatment strategies in chronic hepatitis C].
Deutsche medizinische Wochenschrift (1946) 2012;137(25-26):1360-5.
2012: Bertram Bengsch; Hubert E Blum; Tobias Flecken; Bianca Seigel; Julia Wolanski; Robert Thimme
Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26).
Journal of immunology (Baltimore, Md. : 1950) 2012;188(11):5438-47.
2012: Stefanie Grafmueller; Christoph Neumann-Haefelin; Eva Billerbeck; Hubert E Blum; Robert Thimme
Differential antigen specificity of hepatitis C virus-specific interleukin 17- and interferon γ-producing CD8(+) T cells during chronic infection.
The Journal of infectious diseases 2012;205(7):1142-6.
2012: Jan B Kuhlmann; Hans C Spangenberg; Jan Harder; Hubert E Blum; Matthias Breidert; Wulf Euringer; Richard Fischer
Treatment of unresectable cholangiocarcinoma: conventional transarterial chemoembolization compared with drug eluting bead-transarterial chemoembolization and systemic chemotherapy.
European journal of gastroenterology & hepatology 2012;24(4):437-43.
2012: Gerhild Becker; Hubert E Blum
VEGF Trap for the treatment of malignant ascites.
The lancet oncology 2012;13(2):115-6.
2012: Matthias Fuest; Hubert E Blum; Nicole Fellner; Sabine MacNelly; Guenter P Resch; Karolina Willim; Peter Hasselblatt
The transcription factor c-Jun protects against sustained hepatic endoplasmic reticulum stress thereby promoting hepatocyte survival.
Hepatology (Baltimore, Md.) 2012;55(2):408-18.
2012: Julia Schmidt; Stefan Tenzer; Hubert E Blum; Paul Bowness; Ute Distler; Emma Gostick; Astrid K N Iversen; Paul Klenerman; Volker Lohmann; Christoph Neumann-Haefelin; David A Price; Hansjörg Schild; Robert Thimme
Rapid antigen processing and presentation of a protective and immunodominant HLA-B*27-restricted hepatitis C virus-specific CD8+ T-cell epitope.
PLoS pathogens 2012;8(11):e1003042.
2012: Yu-Hoi Kang; David H Adams; Eleanor J Barnes; Bertram Bengsch; Anisha Bhagwanani; Eva Billerbeck; Hubert E Blum; Vicki Fleming; Ye H Oo; Bianca Seigel; Ruth Simmons; Robert Thimme; Lucy Walker; Chris B Willberg; Paul Klenerman
CD161(+)CD4(+) T cells are enriched in the liver during chronic hepatitis and associated with co-secretion of IL-22 and IFN-γ.
Frontiers in immunology 2012;3():346.
2012: Claudia Trierweiler; Hubert E Blum; Peter Hasselblatt
The transcription factor c-Jun protects against liver damage following activated β-Catenin signaling.
PloS one 2012;7(7):e40638.
2012: Josef Köck; Michael Nassal; Christine Rösler; Hubert E Blum; Jingjing Zhang; Christian Thoma
Human hepatitis B virus production in avian cells is characterized by enhanced RNA splicing and the presence of capsids containing shortened genomes.
PloS one 2012;7(5):e37248.
2011: Hubert E Blum
Gastrointestinal and liver diseases: genetic and epigenetic markers.
Gut 2011;60(12):1630-4.
2011: Martin Kuntz; Hans-Hartmut Peter; Hanspeter Pircher; Susanne Stampf; Robert Thimme; Hubert E Blum; Sigune Goldacker; Klaus Warnatz
Analysis of bulk and virus-specific CD8+ T cells reveals advanced differentiation of CD8+ T cells in patients with common variable immunodeficiency.
Clinical immunology (Orlando, Fla.) 2011;141(2):177-86.
2011: Mario Witkowski; Hubert E Blum; Ekaterina Breous; Nico Büttner; Oliver Drognitz; Ulrich T Hopt; Nadine Kersting; Christoph Neumann-Haefelin; Nasser Semmo; Hans Christian Spangenberg; Robert Thimme
Lack of ex vivo peripheral and intrahepatic α-fetoprotein-specific CD4+ responses in hepatocellular carcinoma.
International journal of cancer. Journal international du cancer 2011;129(9):2171-82.
2011: Nasser Semmo; B Seuthe; Hans Christian Spangenberg; Fikret Er; Hubert E Blum
[A rare cause of an indistinct liver lesion in an elderly woman].
Deutsche medizinische Wochenschrift (1946) 2011;136(23):1251-4.
2011: Daniel Grimm; Robert Thimme; Hubert E Blum
HBV life cycle and novel drug targets.
Hepatology international 2011;5(2):644-53.
2011: M Müller; Hubert E Blum; Fikret Er; Robert Thimme; Nasser Semmo
[Cellular immune response in Hepatitis C infection: role of CD154 expression and clinical relevance].
Deutsche medizinische Wochenschrift (1946) 2011;136(20):1073-7.
2011: Julia Schmidt; Christoph Neumann-Haefelin; Tayibe Altay; Emma Gostick; David A Price; Volker Lohmann; Hubert E Blum; Robert Thimme
Immunodominance of HLA-A2-restricted hepatitis C virus-specific CD8+ T cell responses is linked to naive-precursor frequency.
Journal of virology 2011;85(10):5232-6.
2011: Darius Moradpour; Hubert E Blum
[Viral hepatitis].
Therapeutische Umschau. Revue thérapeutique 2011;68(4):175-81.
2011: Gerhild Becker; Isaak Hatami; Carola Xander; Bettina Dworschak-Flach; Manfred Olschewski; Felix Momm; Peter Deibert; Irene Higginson; Hubert E Blum
Palliative cancer care: an epidemiologic study.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2011;29(6):646-50.
2011: Hubert E Blum
[Personalized medicine].
Praxis 2011;100(3):159-66.
2011: Janos Osztovits; Ferenc Szalay; Judit Tax; Tamas Toth; Levente Csihi; Janos Feher; Evelin Horvath; Tamas Horvath; Márk Kollai; Péter László Lakatos; Levente Littvay; Margit Abonyi; Hubert E Blum
Reversible autonomic dysfunction during antiviral treatment in patients with chronic hepatitis C virus infection: Anti-HCV therapy and autonomic function.
Hepatitis monthly 2011;11(2):114-8.
2011: Hubert E Blum
Hepatocellular carcinoma: HCC.
Hepatitis monthly 2011;11(2):69-70.
2011: Steffen Heeg; Nina Hirt; Angela Queisser; Hannah Schmieg; Michaela Thaler; Heike Kunert; Michael Quante; Gitta Goessel; Alexander von Werder; Jan Harder; Roderick Beijersbergen; Hubert E Blum; Hiroshi Nakagawa; Oliver G Opitz
EGFR overexpression induces activation of telomerase via PI3K/AKT-mediated phosphorylation and transcriptional regulation through Hif1-alpha in a cellular model of oral-esophageal carcinogenesis.
Cancer science 2011;102(2):351-60.
2011: Jürgen S Scheele; Hans C Spangenberg; Zoran Stankovic; Annette Dorn; Jan Harder; Daniel Räpple; Hubert E Blum
Clinical response to Auron Misheil Therapy in a man with advanced multifocal hepatocellular carcinoma: A case report.
Journal of medical case reports 2011;5():478.
2011: Jan B Kuhlmann; Wolfgang Kreisel; Hubert E Blum; Richard Fischer
A severe case of odynophagia.
BMJ (Clinical research ed.) 2011;343():d3137.
2011: D Grimm; Hubert E Blum; Robert Thimme
[Genome-wide association studies].
Deutsche medizinische Wochenschrift (1946) 2011;136(3):95-8.
2010: Volker Brass; Jérôme Gouttenoire; Anja Wahl; Zsuzsanna Pal; Hubert E Blum; François Penin; Darius Moradpour
Hepatitis C virus RNA replication requires a conserved structural motif within the transmembrane domain of the NS5B RNA-dependent RNA polymerase.
Journal of virology 2010;84(21):11580-4.
2010: Elisabeth Panther; Hubert E Blum
[Elevated liver enzymes].
MMW Fortschritte der Medizin 2010;152(37):34-5.
2010: Hubert E Blum
Individualized medicine 2010.
Journal of cellular and molecular medicine 2010;14(9):2257-63.
2010: Hubert E Blum
[Predictive medicine - clinical genetics 2010].
Deutsche medizinische Wochenschrift (1946) 2010;135(25-26):1334-8.
2010: Robert Thimme; Hans Christian Spangenberg; Hubert E Blum
[Hepatology 2010].
Deutsche medizinische Wochenschrift (1946) 2010;135(25-26):1290-4.
2010: Mareike Mueller; Hans Christian Spangenberg; Nadine Kersting; Tayibe Altay; Hubert E Blum; Paul Klenerman; Robert Thimme; Nasser Semmo
Virus-specific CD4+ T cell responses in chronic HCV infection in blood and liver identified by antigen-specific upregulation of CD154.
Journal of hepatology 2010;52(6):800-11.
2010: Eva Billerbeck; Yu-Hoi Kang; Lucy Walker; Helen Lockstone; Stefanie Grafmueller; Vicki Fleming; Jonathan Flint; Chris B Willberg; Bertram Bengsch; Bianca Seigel; Narayan Ramamurthy; Nicole Zitzmann; Eleanor J Barnes; Jonarthan Thevanayagam; Anisha Bhagwanani; Alasdair Leslie; Ye H Oo; Simon Kollnberger; paul BOWNESS; Oliver Drognitz; David H Adams; Hubert E Blum; Robert Thimme; Paul Klenerman
Analysis of CD161 expression on human CD8+ T cells defines a distinct functional subset with tissue-homing properties.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(7):3006-11.
2010: R Fischer; M Breidert; S Paul; Wolfgang Kreisel; Annette Schmitt-Gräff; C Waller; Hubert E Blum
[A patient with chronic diarrhoe, head pigmentation and alopecia. Cronkhite-Canada syndrome].
Deutsche medizinische Wochenschrift (1946) 2010;135(8):339-42.
2010: Josef Köck; Christine Rösler; Jing-Jing Zhang; Hubert E Blum; Michael Nassal; Christian Thoma
Generation of covalently closed circular DNA of hepatitis B viruses via intracellular recycling is regulated in a virus specific manner.
PLoS pathogens 2010;6(9):e1001082.
2010: Peter Deibert; Carola Xander; Hubert E Blum; Gerhild Becker
Methylnaltrexone: the evidence for its use in the management of opioid-induced constipation.
Core evidence 2010;4():247-58.
2010: Bertram Bengsch; Bianca Seigel; Marianne Ruhl; Jörg Timm; Martin Kuntz; Hubert E Blum; Hanspeter Pircher; Robert Thimme
Coexpression of PD-1, 2B4, CD160 and KLRG1 on exhausted HCV-specific CD8+ T cells is linked to antigen recognition and T cell differentiation.
PLoS pathogens 2010;6(6):e1000947.
2010: Gerhild Becker; Dorothee E Kempf; Carola J Xander; Felix Momm; Manfred Olschewski; Hubert E Blum
Four minutes for a patient, twenty seconds for a relative - an observational study at a university hospital.
BMC health services research 2010;10():94.
2010: Hans Christian Spangenberg; Robert Thimme; Hubert E Blum
Evolving treatments of virus-associated HCC: new targets and drugs.
Frontiers in bioscience (Scholar edition) 2010;2():439-53.
2010: Christoph Neumann-Haefelin; Jörg Timm; Julia Schmidt; Nadine Kersting; Karen Fitzmaurice; Cesar Oniangue-Ndza; Michael N Kemper; Isla Humphreys; Susan McKiernan; Dermot Kelleher; Volker Lohmann; paul BOWNESS; Daniela Huzly; Hugo R Rosen; Arthur Y Kim; Georg M Lauer; Todd M Allen; Eleanor Barnes; Michael Roggendorf; Hubert E Blum; Robert Thimme
Protective effect of human leukocyte antigen B27 in hepatitis C virus infection requires the presence of a genotype-specific immunodominant CD8+ T-cell epitope.
Hepatology (Baltimore, Md.) 2010;51(1):54-62.
2009: Marlies H G Langenberg; Carla M L van Herpen; Johann De Bono; Jan H M Schellens; Clemens Unger; Klaas Hoekman; Hubert E Blum; Walter Fiedler; Joachim Drevs; Florence Le Maulf; Anitra Fielding; Jane Robertson; Emile E Voest
Effective strategies for management of hypertension after vascular endothelial growth factor signaling inhibition therapy: results from a phase II randomized, factorial, double-blind study of Cediranib in patients with advanced solid tumors.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(36):6152-9.
2009: Birke Bartosch; Robert Thimme; Hubert E Blum; Fabien Zoulim
Hepatitis C virus-induced hepatocarcinogenesis.
Journal of hepatology 2009;51(4):810-20.
2009: Jan Harder; Oliver Waiz; Florian Otto; Michael Geissler; Manfred Olschewski; Brigitte Weinhold; Hubert E Blum; Annette Schmitt-Graeff; Oliver G Opitz
EGFR and HER2 expression in advanced biliary tract cancer.
World journal of gastroenterology : WJG 2009;15(36):4511-7.
2009: Bertram Bengsch; Robert Thimme; Hubert E Blum
Role of host genetic factors in the outcome of hepatitis C virus infection.
Viruses 2009;1(2):104-25.
2009: Hans Christian Spangenberg; Robert Thimme; Hubert E Blum
Targeted therapy for hepatocellular carcinoma.
Nature reviews. Gastroenterology & hepatology 2009;6(7):423-32.
2009: Pantxika Bellecave; Jérôme Gouttenoire; Markus Gajer; Volker Brass; George Koutsoudakis; Hubert E Blum; Ralf Bartenschlager; Michael Nassal; Darius Moradpour
Hepatitis B and C virus coinfection: a novel model system reveals the absence of direct viral interference.
Hepatology (Baltimore, Md.) 2009;50(1):46-55.
2009: Eva Billerbeck; Nobuhiro Nakamoto; Bianca Seigel; Hubert E Blum; Kyong-Mi Chang; Robert Thimme
Determinants of in vitro expansion of different human virus-specific FoxP3+ regulatory CD8+ T cells in chronic hepatitis C virus infection.
The Journal of general virology 2009;90(Pt 7):1692-701.
2009: Robert Thimme; Hans Christian Spangenberg; Hubert E Blum
[Hepatology 2009].
Deutsche medizinische Wochenschrift (1946) 2009;134(25-26):1335-9.
2009: Jérôme Gouttenoire; Valérie Castet; Roland Montserret; Naveen Arora; Vincent Raussens; Jean-Marie Ruysschaert; Eric Diesis; Hubert E Blum; François Penin; Darius Moradpour
Identification of a novel determinant for membrane association in hepatitis C virus nonstructural protein 4B.
Journal of virology 2009;83(12):6257-68.
2009: Gerhild Becker; Hubert E Blum
Novel opioid antagonists for opioid-induced bowel dysfunction and postoperative ileus.
Lancet 2009;373(9670):1198-206.
2009: Juandy Jo; Ulrike Aichele; Nadine Kersting; Rahel Klein; Peter Aichele; Emmanuel Bisse; Andrew K Sewell; Hubert E Blum; Ralf Bartenschlager; Volker Lohmann; Robert Thimme
Analysis of CD8+ T-cell-mediated inhibition of hepatitis C virus replication using a novel immunological model.
Gastroenterology 2009;136(4):1391-401.
2009: Eva Dazert; Christoph Neumann-Haefelin; Stéphane Bressanelli; Karen Fitzmaurice; Julia Kort; Jörg Timm; Susan McKiernan; Dermot Kelleher; Norbert Gruener; John E Tavis; Hugo R Rosen; Jaqueline Shaw; paul BOWNESS; Hubert E Blum; Paul Klenerman; Ralf Bartenschlager; Robert Thimme
Loss of viral fitness and cross-recognition by CD8+ T cells limit HCV escape from a protective HLA-B27-restricted human immune response.
The Journal of clinical investigation 2009;119(2):376-86.
2009: Jan Harder; V Engelstaedter; H Usadel; S Lassmann; M Werner; P Baier; Florian Otto; M Varbanova; E Schaeffner; Manfred Olschewski; Hubert E Blum; Oliver G Opitz
CpG-island methylation of the ER promoter in colorectal cancer: analysis of micrometastases in lymph nodes from UICC stage I and II patients.
British journal of cancer 2009;100(2):360-5.
2009: Zhan-Fei Tian; Hong Shen; Xi-Hua Fu; Yi-Chun Chen; Hubert E Blum; Thomas F Baumert; Xi-Ping Zhao
Interaction of hepatitis C virus envelope glycoprotein E2 with the large extracellular loop of tupaia CD81.
World journal of gastroenterology : WJG 2009;15(2):240-4.
2009: Marco Hoffmann; Mirjam B Zeisel; Nikolaus Jilg; Glaucia Paranhos-Baccalà; Françoise Stoll-Keller; Takaji Wakita; Peter Hafkemeyer; Hubert E Blum; Heidi Barth; Philipp Henneke; Thomas F Baumert
Toll-like receptor 2 senses hepatitis C virus core protein but not infectious viral particles.
Journal of innate immunity 2009;1(5):446-54.
2009: Leonie Halverscheid; Peter Deibert; René Schmidt; Hubert E Blum; Torsten Dunkern; Benedikt H J Pannen; Wolfgang Kreisel
Phosphodiesterase-5 inhibitors have distinct effects on the hemodynamics of the liver.
BMC gastroenterology 2009;9():69.
2008: Robert Thimme; Michaela Neagu; Tobias Boettler; Christoph Neumann-Haefelin; Nadine Kersting; Michael Geissler; Frank Makowiec; Robert Obermaier; Ulrich T Hopt; Hubert E Blum; Hans Christian Spangenberg
Comprehensive analysis of the alpha-fetoprotein-specific CD8+ T cell responses in patients with hepatocellular carcinoma.
Hepatology (Baltimore, Md.) 2008;48(6):1821-33.
2008: Christoph Neumann-Haefelin; Hubert E Blum; Robert Thimme
[RNA interference as antiviral strategy].
Deutsche medizinische Wochenschrift (1946) 2008;133(46):2407-9.
2008: Anita Haberstroh; Eva K Schnober; Mirjam B Zeisel; Patric Carolla; Heidi Barth; Hubert E Blum; François-Loïc Cosset; George Koutsoudakis; Ralf Bartenschlager; Ann union; Erik Depla; Ania Owsianka; Arvind H Patel; Catherine Schuster; Françoise Stoll-Keller; Michel Doffoël; Marlène Dreux; Thomas F Baumert
Neutralizing host responses in hepatitis C virus infection target viral entry at postbinding steps and membrane fusion.
Gastroenterology 2008;135(5):1719-1728.e1.
2008: Elisabeth Panther; Hubert E Blum
[Liver diseases in pregnancy].
Deutsche medizinische Wochenschrift (1946) 2008;133(44):2283-7.
2008: Lin Lan; Sebastian Gorke; Sibylle J Rau; Mirjam B Zeisel; Eberhard Hildt; Kiyoshi Himmelsbach; Monica Carvajal-Yepes; Roman Huber; Takaji Wakita; Annette Schmitt-Graeff; Cathy Royer; Hubert E Blum; Richard Fischer; Thomas F Baumert
Hepatitis C virus infection sensitizes human hepatocytes to TRAIL-induced apoptosis in a caspase 9-dependent manner.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4926-35.
2008: Christian N Arnold; Takeshi Nagasaka; Ajay Goel; Iris Scharf; Patricia Grabowski; Andrea Sosnowski; Annette Schmitt-Gräff; C Richard Boland; Rudolf Arnold; Hubert E Blum
Molecular characteristics and predictors of survival in patients with malignant neuroendocrine tumors.
International journal of cancer. Journal international du cancer 2008;123(7):1556-64.
2008: Volker Brass; Jan Martin Berke; Roland Montserret; Hubert E Blum; François Penin; Darius Moradpour
Structural determinants for membrane association and dynamic organization of the hepatitis C virus NS3-4A complex.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(38):14545-50.
2008: Hans Christian Spangenberg; Robert Thimme; Hubert E Blum
Evolving therapies in the treatment of hepatocellular carcinoma.
Biologics : targets & therapy 2008;2(3):453-62.
2008: Henning Schwacha; Hubert E Blum; Peter Hafkemeyer
Endoscopic therapy of gallstones ileus.
Endoscopy 2008;40 Suppl 2():E185-6.
2008: C Arnold; S von Sanden; C Theilacker; Hubert E Blum
[Ulcerous colitis and infection with cytomegalovirus, herpes simplex virus and clostridium difficile].
Zeitschrift für Gastroenterologie 2008;46(8):780-3.
2008: Elisabeth Panther; Robert Thimme; Hubert E Blum
[Jaundice in an HIV-positive pregnant woman].
Deutsche medizinische Wochenschrift (1946) 2008;133(30):1560-2.
2008: María Matilde Bartolomé Rodríguez; Seung-Min Ryu; Cheng Qian; Michael Geissler; Christian F Grimm; Jesús Prieto; Hubert E Blum; Leonhard Mohr
Immunotherapy of murine hepatocellular carcinoma by alpha-fetoprotein DNA vaccination combined with adenovirus-mediated chemokine and cytokine expression.
Human gene therapy 2008;19(7):753-9.
2008: Jan Harder; Oliver G Opitz; Jan Brabender; Manfred Olschewski; Hubert E Blum; Shuji Nomoto; Henning Usadel
Quantitative promoter methylation analysis of hepatocellular carcinoma, cirrhotic and normal liver.
International journal of cancer. Journal international du cancer 2008;122(12):2800-4.
2008: Robert Thimme; Hans Christian Spangenberg; Hubert E Blum
[Hepatology 2008].
Deutsche medizinische Wochenschrift (1946) 2008;133(25-26):1366-9.
2008: Felix Flohr; Jan Harder; Jochen Seufert; Hubert E Blum; Hans C Spangenberg
Hypothyroidism in patients with hepatocellular carcinoma treated by transarterial chemoembolization.
Hepatology (Baltimore, Md.) 2008;47(6):2144.
2008: Christoph Neumann-Haefelin; Jörg Timm; Hans Christian Spangenberg; Natalie Wischniowski; Natalja Nazarova; Nadine Kersting; Michael Roggendorf; Todd M Allen; Hubert E Blum; Robert Thimme
Virological and immunological determinants of intrahepatic virus-specific CD8+ T-cell failure in chronic hepatitis C virus infection.
Hepatology (Baltimore, Md.) 2008;47(6):1824-36.
2008: Peter Hafkemeyer; Ulrich Brinkmann; Elizabeth Brinkmann; Ira Pastan; Hubert E Blum; Thomas F Baumert
Pseudomonas exotoxin antisense RNA selectively kills hepatitis B virus infected cells.
World journal of gastroenterology : WJG 2008;14(18):2810-7.
2008: Robert Thimme; Christoph Neumann-Haefelin; Tobias Boettler; Hubert E Blum
Adaptive immune responses to hepatitis C virus: from viral immunobiology to a vaccine.
Biological chemistry 2008;389(5):457-67.
2008: Josef Köck; Hubert E Blum
Hypermutation of hepatitis B virus genomes by APOBEC3G, APOBEC3C and APOBEC3H.
The Journal of general virology 2008;89(Pt 5):1184-91.
2008: Leonie Halverscheid; Nina K Mannes; Robert Weth; Manuela Kleinschmidt; Ursula Schultz; Kurt Reifenberg; Reinhold Schirmbeck; Michael Nassal; Hubert E Blum; Jörg Reimann; Michael Geissler
Transgenic mice replicating hepatitis B virus but lacking expression of the major HBsAg.
Journal of medical virology 2008;80(4):583-90.
2008: Heidi Barth; Eva K Schnober; Christoph Neumann-Haefelin; Christine Thumann; Mirjam B Zeisel; Helmut M Diepolder; Zongyi Hu; TSANYANG LIANG; Hubert E Blum; Robert Thimme; Mélanie Lambotin; Thomas F Baumert
Scavenger receptor class B is required for hepatitis C virus uptake and cross-presentation by human dendritic cells.
Journal of virology 2008;82(7):3466-79.
2008: Robert Thimme; Hans Christian Spangenberg; Hubert E Blum
[Chronic hepatitis B].
Deutsche medizinische Wochenschrift (1946) 2008;133(4):135-8.
2007: Hubert E Blum
[From skin to pluripotent stem cells: reprogramming of adult somatic cells].
Deutsche medizinische Wochenschrift (1946) 2007;132(51-52):2774-6.
2007: N Semmo; Hans Christian Spangenberg; Hubert E Blum
[Percutaneous liver biopsy].
Deutsche medizinische Wochenschrift (1946) 2007;132(49):2643-5.
2007: Mirjam B Zeisel; George Koutsoudakis; Eva K Schnober; Anita Haberstroh; Hubert E Blum; François-Loïc Cosset; Takaji Wakita; Daniel Jaeck; Michel Doffoel; Cathy Royer; Eric Soulier; Evelyne Schvoerer; Catherine Schuster; Françoise Stoll-Keller; Ralf Bartenschlager; Thomas Pietschmann; Heidi Barth; Thomas F Baumert
Scavenger receptor class B type I is a key host factor for hepatitis C virus infection required for an entry step closely linked to CD81.
Hepatology (Baltimore, Md.) 2007;46(6):1722-31.
2007: Volker Brass; Darius Moradpour; Hubert E Blum
Hepatitis C virus infection: in vivo and in vitro models.
Journal of viral hepatitis 2007;14 Suppl 1():64-7.
2007: Gerhild Becker; Daniel Galandi; Hubert E Blum
Peripherally acting opioid antagonists in the treatment of opiate-related constipation: a systematic review.
Journal of pain and symptom management 2007;34(5):547-65.
2007: Y Folmer; M Schneider; Hubert E Blum; Peter Hafkemeyer
Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-ABCC2 antisense constructs.
Cancer gene therapy 2007;14(11):875-84.
2007: Clemens Kreutz; M M Bartolome Rodriguez; Thomas Maiwald; M Seidl; Hubert E Blum; L Mohr; Jens Timmer
An error model for protein quantification.
Bioinformatics (Oxford, England) 2007;23(20):2747-53.
2007: Richard Fischer; Thomas F Baumert; Hubert E Blum
Hepatitis C virus infection and apoptosis.
World journal of gastroenterology : WJG 2007;13(36):4865-72.
2007: Christoph Neumann-Haefelin; Hans Christian Spangenberg; Hubert E Blum; Robert Thimme
Host and viral factors contributing to CD8+ T cell failure in hepatitis C virus infection.
World journal of gastroenterology : WJG 2007;13(36):4839-47.
2007: Hans Christian Spangenberg; Robert Thimme; Leonhard Mohr; Hubert E Blum
[The hepatocellular carcinoma: alternative therapeutical strategies].
Zentralblatt für Chirurgie 2007;132(4):322-7.
2007: Eva Billerbeck; Hubert E Blum; Robert Thimme
Parallel expansion of human virus-specific FoxP3- effector memory and de novo-generated FoxP3+ regulatory CD8+ T cells upon antigen recognition in vitro.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(2):1039-48.
2007: Hubert E Blum; Hans Christian Spangenberg
Hepatocellular carcinoma: an update.
Archives of Iranian medicine 2007;10(3):361-71.
2007: Christoph Neumann-Haefelin; Thomas Killinger; Jörg Timm; Scott Southwood; Denise McKinney; Hubert E Blum; Robert Thimme
Absence of viral escape within a frequently recognized HLA-A26-restricted CD8+ T-cell epitope targeting the functionally constrained hepatitis C virus NS5A/5B cleavage site.
The Journal of general virology 2007;88(Pt 7):1986-91.
2007: Gerhild Becker; Robert Sarhatlic; Manfred Olschewski; Carola Xander; Felix Momm; Hubert E Blum
End-of-life care in hospital: current practice and potentials for improvement.
Journal of pain and symptom management 2007;33(6):711-9.
2007: Christian N Arnold; Andrea Sosnowski; Annette Schmitt-Gräff; Rudolf Arnold; Hubert E Blum
Analysis of molecular pathways in sporadic neuroendocrine tumors of the gastro-entero-pancreatic system.
International journal of cancer. Journal international du cancer 2007;120(10):2157-64.
2007: Hubert E Blum
[Stem cells--basic aspects and therapeutic perspectives].
Praxis 2007;96(14):539-43.
2007: Jan M Pestka; Mirjam B Zeisel; Edith Bläser; Peter Schürmann; Birke Bartosch; François-Loïc Cosset; Arvind H Patel; Helga Meisel; Jens Baumert; Sergei Viazov; Kay Rispeter; Hubert E Blum; Michael Roggendorf; Thomas F Baumert
Rapid induction of virus-neutralizing antibodies and viral clearance in a single-source outbreak of hepatitis C.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(14):6025-30.
2007: Gerhild Becker; Carola Xander; Hubert E Blum; Johannes Lutterbach; Felix Momm; Marjolein Gysels; Irene Higginson
Do religious or spiritual beliefs influence bereavement? A systematic review.
Palliative medicine 2007;21(3):207-17.
2007: Volker Brass; Zsuzsanna Pal; Nicolas Sapay; Gilbert Deléage; Hubert E Blum; François Penin; Darius Moradpour
Conserved determinants for membrane association of nonstructural protein 5A from hepatitis C virus and related viruses.
Journal of virology 2007;81(6):2745-57.
2007: Ankur Goyal; Wolf Peter Hofmann; Eva Hermann; Stella Traver; Syed Hissar; Naveen Arora; Hubert E Blum; Stefan Zeuzem; Christoph Sarrazin; Shiv K Sarin
The hepatitis C virus NS5A protein and response to interferon alpha: mutational analyses in patients with chronic HCV genotype 3a infection from India.
Medical microbiology and immunology 2007;196(1):11-21.
2007: Gerhild Becker; V Dausch; Carola Xander; Manfred Olschewski; Felix Momm; Hubert E Blum
[Palliative medicine content in German-language medical textbooks].
Deutsche medizinische Wochenschrift (1946) 2007;132(6):256-60.
2007: Hinrich C Bremer; Wolfgang Kreisel; Kai Roecker; Michael Dreher; Daniel Koenig; Anna Katharina Kurz-Schmieg; Hubert E Blum; Martin Roessle; Peter Deibert
Phosphodiesterase 5 inhibitors lower both portal and pulmonary pressure in portopulmonary hypertension: a case report.
Journal of medical case reports 2007;1():46.
2007: Hans Christian Spangenberg; Leonhard Mohr; Hubert E Blum
[Regional therapy of liver tumors].
Der Internist 2007;48(1):40-5.
2007: Bertram Bengsch; Hans Christian Spangenberg; Nadine Kersting; Christoph Neumann-Haefelin; Elisabeth Panther; Fritz von Weizsäcker; Hubert E Blum; Hanspeter Pircher; Robert Thimme
Analysis of CD127 and KLRG1 expression on hepatitis C virus-specific CD8+ T cells reveals the existence of different memory T-cell subsets in the peripheral blood and liver.
Journal of virology 2007;81(2):945-53.
2006: Heidi Barth; Eva K Schnober; Fuming Zhang; Robert J Linhardt; Erik Depla; Bertrand Boson; François-Loïc Cosset; Arvind H Patel; Hubert E Blum; Thomas F Baumert
Viral and cellular determinants of the hepatitis C virus envelope-heparan sulfate interaction.
Journal of virology 2006;80(21):10579-90.
2006: Hans Christian Spangenberg; Hubert E Blum
[Vasculitis and liver disease].
Praxis 2006;95(40):1557-62.
2006: Robert Thimme; Hubert E Blum
[Therapy of hepatitis B].
Praxis 2006;95(36):1383-8.
2006: Hubert E Blum
[Chronic liver disease--diagnostic work-up].
Praxis 2006;95(34):1271-4.
2006: Christoph Neumann-Haefelin; Hubert E Blum; Robert Thimme
[Immunological T cell analyses -- current state and clinical relevance].
Deutsche medizinische Wochenschrift (1946) 2006;131(22):1273-8.
2006: Xinhua Fang; Mirjam B Zeisel; Jochen Wilpert; Bettina Gissler; Robert Thimme; Clemens Kreutz; Thomas Maiwald; Jens Timmer; Winfried V Kern; Johannes Donauer; Marcel Geyer; Gerd Walz; Erik Depla; Fritz von Weizsäcker; Hubert E Blum; Thomas F Baumert
Host cell responses induced by hepatitis C virus binding.
Hepatology (Baltimore, Md.) 2006;43(6):1326-36.
2006: A K Kurz; Hubert E Blum
[Duplexsonography of the liver: state-of-the-art and perspectives].
Deutsche medizinische Wochenschrift (1946) 2006;131(18):1035-9.
2006: Tobias Boettler; Elisabeth Panther; Bertram Bengsch; Natalja Nazarova; Hans Christian Spangenberg; Hubert E Blum; Robert Thimme
Expression of the interleukin-7 receptor alpha chain (CD127) on virus-specific CD8+ T cells identifies functionally and phenotypically defined memory T cells during acute resolving hepatitis B virus infection.
Journal of virology 2006;80(7):3532-40.
2006: Christoph Neumann-Haefelin; Susan McKiernan; Scott Ward; Sergei Viazov; Hans Christian Spangenberg; Thomas Killinger; Thomas F Baumert; Natalja Nazarova; Isabelle Sheridan; Oliver G Pybus; Fritz von Weizsäcker; Michael Roggendorf; Dermot Kelleher; Paul Klenerman; Hubert E Blum; Robert Thimme
Dominant influence of an HLA-B27 restricted CD8+ T cell response in mediating HCV clearance and evolution.
Hepatology (Baltimore, Md.) 2006;43(3):563-72.
2006: Gerhild Becker; Daniel Galandi; Hubert E Blum
Malignant ascites: systematic review and guideline for treatment.
European journal of cancer (Oxford, England : 1990) 2006;42(5):589-97.
2006: Volker Brass; Darius Moradpour; Hubert E Blum
Molecular virology of hepatitis C virus (HCV): 2006 update.
International journal of medical sciences 2006;3(2):29-34.
2006: Peter Deibert; Yorck Schumacher; G Ruecker; Oliver G Opitz; Hubert E Blum; Martin Rössle; Wolfgang Kreisel
Effect of vardenafil, an inhibitor of phosphodiesterase-5, on portal haemodynamics in normal and cirrhotic liver -- results of a pilot study.
Alimentary pharmacology & therapeutics 2006;23(1):121-8.
2005: Kai M Rösler; Robert Thimme; Hans Christian Spangenberg; Hubert E Blum
[The patient as partner -- observations regarding a respectful relationship with sick people].
Deutsche medizinische Wochenschrift (1946) 2005;130(51-52):2937-9.
2005: Hubert E Blum
Hepatocellular carcinoma: therapy and prevention.
World journal of gastroenterology : WJG 2005;11(47):7391-400.
2005: Hubert E Blum
[Hepatocellular carcinoma].
Deutsche medizinische Wochenschrift (1946) 2005;130 Suppl 5():S221-3.
2005: Christian N Arnold; Ajay Goel; Hubert E Blum; C Richard Boland
Molecular pathogenesis of colorectal cancer: implications for molecular diagnosis.
Cancer 2005;104(10):2035-47.
2005: Mona Y Ali; Christian F Grimm; Marcus Ritter; Leonhard Mohr; Hans-Peter Allgaier; Robert Weth; Wulf O Bocher; Katja Endrulat; Hubert E Blum; Michael Geissler
Activation of dendritic cells by local ablation of hepatocellular carcinoma.
Journal of hepatology 2005;43(5):817-22.
2005: Michael Quante; Steffen Heeg; Alexander von Werder; Gitta Goessel; Christine Fulda; Michaela Doebele; Hiroshi Nakagawa; Roderick L Beijersbergen; Hubert E Blum; Oliver G Opitz
Differential transcriptional regulation of human telomerase in a cellular model representing important genetic alterations in esophageal squamous carcinogenesis.
Carcinogenesis 2005;26(11):1879-89.
2005: Gitta Goessel; Michael Quante; William C Hahn; Hideki Harada; Steffen Heeg; Yasir Suliman; Michaela Doebele; Alexander von Werder; Christine Fulda; Hiroshi Nakagawa; Anil K Rustgi; Hubert E Blum; Oliver G Opitz
Creating oral squamous cancer cells: a cellular model of oral-esophageal carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(43):15599-604.
2005: Hans Christian Spangenberg; Sergei Viazov; Nadine Kersting; Christoph Neumann-Haefelin; Denise McKinney; Michael Roggendorf; Fritz von Weizsäcker; Hubert E Blum; Robert Thimme
Intrahepatic CD8+ T-cell failure during chronic hepatitis C virus infection.
Hepatology (Baltimore, Md.) 2005;42(4):828-37.
2005: Robert Thimme; Victor Appay; Marie Koschella; Elisabeth Panther; Evelyn Roth; Andrew D Hislop; Alan B Rickinson; Sarah L Rowland-Jones; Hubert E Blum; Hanspeter Pircher
Increased expression of the NK cell receptor KLRG1 by virus-specific CD8 T cells during persistent antigen stimulation.
Journal of virology 2005;79(18):12112-6.
2005: Gerhild Becker; Felix Momm; Henning Schwacha; Norbert Hodapp; Henning Usadel; Michael Geissler; Annette Barke; Annette Schmitt-Gräff; Karl Henne; Hubert E Blum
Klatskin tumor treated by inter-disciplinary therapies including stereotactic radiotherapy: a case report.
World journal of gastroenterology : WJG 2005;11(31):4923-6.
2005: Christine Rösler; Josef Köck; Michael Kann; Michael H Malim; Hubert E Blum; Thomas F Baumert; Fritz von Weizsäcker
APOBEC-mediated interference with hepadnavirus production.
Hepatology (Baltimore, Md.) 2005;42(2):301-9.
2005: Thomas F Baumert; Josef Köck; Hubert E Blum
A novel target of hepatitis B virus mutations: splicing of surface RNA.
Hepatology (Baltimore, Md.) 2005;42(1):21-3.
2005: C F Grimm; Hubert E Blum; Michael Geissler
[Tyrosine kinase inhibitors in tumor therapy--part 2. Current position and perspectives].
Deutsche medizinische Wochenschrift (1946) 2005;130(23):1438-42.
2005: Rainer Gosert; Wiebke Jendrsczok; Jan Martin Berke; Volker Brass; Hubert E Blum; Darius Moradpour
Characterization of nonstructural protein membrane anchor deletion mutants expressed in the context of the hepatitis C virus polyprotein.
Journal of virology 2005;79(12):7911-7.
2005: Tobias Boettler; Hans Christian Spangenberg; Christoph Neumann-Haefelin; Elisabeth Panther; Simonetta Urbani; Carlo Ferrari; Hubert E Blum; Fritz von Weizsäcker; Robert Thimme
T cells with a CD4+CD25+ regulatory phenotype suppress in vitro proliferation of virus-specific CD8+ T cells during chronic hepatitis C virus infection.
Journal of virology 2005;79(12):7860-7.
2005: Benno Wölk; Christel Gremion; Natalia Ivashkina; Olivier B Engler; Benno Grabscheid; Elke Bieck; Hubert E Blum; Andreas Cerny; Darius Moradpour
Stable human lymphoblastoid cell lines constitutively expressing hepatitis C virus proteins.
The Journal of general virology 2005;86(Pt 6):1737-46.
2005: C F Grimm; Hubert E Blum; Michael Geissler
[Tyrosine kinase inhibitors in tumor therapy--part 1. Molecular and genetic fundamentals].
Deutsche medizinische Wochenschrift (1946) 2005;130(21):1318-22.
2005: Darius Moradpour; Hubert E Blum
Pathogenesis of hepatocellular carcinoma.
European journal of gastroenterology & hepatology 2005;17(5):477-83.
2005: Hubert E Blum
Liver cancer.
European journal of gastroenterology & hepatology 2005;17(5):475-6.
2005: Heidi Barth; Raffaele Cerino; Mirko Arcuri; Marco Hoffmann; Peter Schürmann; Mohammed I Adah; Bettina Gissler; Xiping Zhao; Valeria Ghisetti; Bruna Lavezzo; Hubert E Blum; Fritz von Weizsäcker; alessandra vitelli; Elisa Scarselli; Thomas F Baumert
Scavenger receptor class B type I and hepatitis C virus infection of primary tupaia hepatocytes.
Journal of virology 2005;79(9):5774-85.
2005: Heidi Barth; Axel Ulsenheimer; Gerd R Pape; Helmut M Diepolder; Marco Hoffmann; Christoph Neumann-Haefelin; Robert Thimme; Philipp Henneke; Reinhild Klein; Glaucia Paranhos-Baccalà; Erik Depla; TSANYANG LIANG; Hubert E Blum; Thomas F Baumert
Uptake and presentation of hepatitis C virus-like particles by human dendritic cells.
Blood 2005;105(9):3605-14.
2005: C N Arnold; Hubert E Blum
[Colon cancer: molecular pathogenesis and clinical relevance].
Deutsche medizinische Wochenschrift (1946) 2005;130(13):809-11.
2005: J Harder; K Mikesch; Leonhard Mohr; Hubert E Blum
[Seizures following Billroth II gastrectomy].
Deutsche medizinische Wochenschrift (1946) 2005;130(11):574-6.
2005: Hubert E Blum
Treatment of hepatocellular carcinoma.
Best practice & research. Clinical gastroenterology 2005;19(1):129-45.
2005: Thomas F Baumert; Chun Yang; Peter Schürmann; Josef Köck; Christian Ziegler; Carsten Grüllich; Michael Nassal; TSANYANG LIANG; Hubert E Blum; Fritz von Weizsäcker
Hepatitis B virus mutations associated with fulminant hepatitis induce apoptosis in primary Tupaia hepatocytes.
Hepatology (Baltimore, Md.) 2005;41(2):247-56.
2005: Darius Moradpour; Hubert E Blum
[Diagnosis of hepatitis B and C].
Praxis 2005;94(3):66-72.
2005: Hubert E Blum
[Gene therapy for liver diseases--facts or fiction].
Praxis 2005;94(3):59-63.
2005: Robert Thimme; Hans Christian Spangenberg; Hubert E Blum
Hepatitis B or hepatitis C and human immunodeficiency virus infection.
Journal of hepatology 2005;42 Suppl(1):S37-44.
2005: Oliver G Opitz; Michael Quante; Alexander von Werder; Steffen Heeg; Hubert E Blum
A mouse model of oral-esophageal carcinogenesis.
Onkologie 2005;28(1):44-8.
2005: Peter Hasselblatt; Birgit Hockenjos; Christian Thoma; Hubert E Blum; Wolf-Bernhard Offensperger
Translation of stable hepadnaviral mRNA cleavage fragments induced by the action of phosphorothioate-modified antisense oligodeoxynucleotides.
Nucleic acids research 2005;33(1):114-25.
2005: Maura Dandri; Martin R Burda; David M Zuckerman; Karsten Wursthorn; Urte Matschl; Jörg-Matthias Pollok; Xavier Rogiers; Andreas Gocht; Josef Köck; Hubert E Blum; Fritz von Weizsäcker; Jörg Petersen
Chronic infection with hepatitis B viruses and antiviral drug evaluation in uPA mice after liver repopulation with tupaia hepatocytes.
Journal of hepatology 2005;42(1):54-60.
2004: Michael Geissler; H Schwacha; S Eggstein; Henning Usadel; Jan Harder; Oliver G Opitz; C Arnold; C F Grimm; Hubert E Blum
[Esophageal carcinoma: non-surgical therapy].
Praxis 2004;93(49):2057-64.
2004: Marcus Ritter; Mona Y Ali; Christian F Grimm; Robert Weth; Leonhard Mohr; Wulf O Bocher; Katja Endrulat; Heiner Wedemeyer; Hubert E Blum; Michael Geissler
Immunoregulation of dendritic and T cells by alpha-fetoprotein in patients with hepatocellular carcinoma.
Journal of hepatology 2004;41(6):999-1007.
2004: Darius Moradpour; Hubert E Blum
A primer on the molecular virology of hepatitis C.
Liver international : official journal of the International Association for the Study of the Liver 2004;24(6):519-25.
2004: Josef Köck; Michael Nassal; Karl Deres; Hubert E Blum; Fritz von Weizsäcker
Hepatitis B virus nucleocapsids formed by carboxy-terminally mutated core proteins contain spliced viral genomes but lack full-size DNA.
Journal of virology 2004;78(24):13812-8.
2004: Darius Moradpour; Volker Brass; Elke Bieck; Peter Friebe; Rainer Gosert; Hubert E Blum; Ralf Bartenschlager; François Penin; Volker Lohmann
Membrane association of the RNA-dependent RNA polymerase is essential for hepatitis C virus RNA replication.
Journal of virology 2004;78(23):13278-84.
2004: François Penin; Volker Brass; Nicole Appel; Stéphanie Ramboarina; Roland Montserret; Damien Ficheux; Hubert E Blum; Ralf Bartenschlager; Darius Moradpour
Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A.
The Journal of biological chemistry 2004;279(39):40835-43.
2004: Christine Rösler; Josef Köck; Michael H Malim; Hubert E Blum; Fritz von Weizsäcker
Comment on "Inhibition of hepatitis B virus replication by APOBEC3G".
Science (New York, N.Y.) 2004;305(5689):1403; author reply 1403.
2004: Fritz von Weizsäcker; Hubert E Blum
Out of control: hepatitis B reactivation by transarterial treatment of hepatocellular carcinoma.
Journal of hepatology 2004;41(3):482-4.
2004: Daniel Steinmann; Heidi Barth; Bettina Gissler; Peter Schürmann; Mohammed I Adah; J Tilman Gerlach; Gerd R Pape; Erik Depla; Dirk Jacobs; Geert Maertens; Arvind H Patel; Geneviève Inchauspé; TSANYANG LIANG; Hubert E Blum; Thomas F Baumert
Inhibition of hepatitis C virus-like particle binding to target cells by antiviral antibodies in acute and chronic hepatitis C.
Journal of virology 2004;78(17):9030-40.
2004: Robert Thimme; Oliver G Opitz; Hubert E Blum; Wolfgang Kreisel
[Cholestatic liver diseases].
Therapeutische Umschau. Revue thérapeutique 2004;61(8):521-7.
2004: Hans Christian Spangenberg; Kai M Rösler; Hubert E Blum
[Hereditary liver diseases].
Therapeutische Umschau. Revue thérapeutique 2004;61(8):513-20.
2004: D Moradpour; Hubert E Blum
[Hepatitis C].
Therapeutische Umschau. Revue thérapeutique 2004;61(8):493-8.
2004: Hubert E Blum
[Hepatitis 2004: an update].
Therapeutische Umschau. Revue thérapeutique 2004;61(8):477-9.
2004: Hubert E Blum; T Berg; Hans L Tillmann; Fritz von Weizsäcker
[Procedures for problematic situations with hepatitis B].
Zeitschrift für Gastroenterologie 2004;42(8):692-7.
2004: Volker Brass; Hubert E Blum; Darius Moradpour
Recent developments in target identification against hepatitis C virus.
Expert opinion on therapeutic targets 2004;8(4):295-307.
2004: Gerhild Becker; Hubert E Blum
["Medical futility": the doctor caught between the demands for and the limitations of treatment].
Deutsche medizinische Wochenschrift (1946) 2004;129(31-32):1694-7.
2004: Christoph Neumann-Haefelin; Hans Christian Spangenberg; Robert Thimme; Hubert E Blum
[Suppressor T-cells: immunologic regulator cells and clinical perspectives].
Deutsche medizinische Wochenschrift (1946) 2004;129(30):1627-30.
2004: Darius Moradpour; Matthew J Evans; Rainer Gosert; Zhenghong Yuan; Hubert E Blum; Stephen P Goff; Brett D Lindenbach; Charles M Rice
Insertion of green fluorescent protein into nonstructural protein 5A allows direct visualization of functional hepatitis C virus replication complexes.
Journal of virology 2004;78(14):7400-9.
2004: Hans Christian Spangenberg; Robert Thimme; Fritz von Weizsäcker; Hubert E Blum
[Best supportive care of hepatocellular carcinoma].
Der Internist 2004;45(7):777-85.
2004: Hans Christian Spangenberg; Robert Thimme; Hubert E Blum
Tracking cccDNA in chronic HBV infection.
Hepatology (Baltimore, Md.) 2004;39(6):1736-8.
2004: Roman Huber; Birgit Hockenjos; Hubert E Blum
DDB treatment of patients with chronic hepatitis.
Hepatology (Baltimore, Md.) 2004;39(6):1732-3.
2004: Christian N Arnold; Andrea Sosnowski; Hubert E Blum
Analysis of molecular pathways in neuroendocrine cancers of the gastroenteropancreatic system.
Annals of the New York Academy of Sciences 2004;1014():218-9.
2004: Hans Christian Spangenberg; I Zuber-Jerger; Leonhard Mohr; Robert Thimme; Hubert E Blum
[Diagnosis and treatment of hepatocellular carcinoma].
Deutsche medizinische Wochenschrift (1946) 2004;129(8):368-72.
2004: Elisabeth Panther; Hans Christian Spangenberg; Christoph Neumann-Haefelin; Kai M Rösler; Hubert E Blum; Fritz von Weizsäcker; Robert Thimme
[The role of the virus specific T-cell response in acute and chronic HBV and HCV infection].
Zeitschrift für Gastroenterologie 2004;42(1):39-46.
2004: I Zuber-Jerger; Michael Geissler; Hans Christian Spangenberg; Leonhard Mohr; F Weizsäcker; Hubert E Blum
[Local ablation of malignant lesions of the liver - potential applications and limitations of the different methods].
Zeitschrift für Gastroenterologie 2004;42(1):31-8.
2004: Fritz von Weizsäcker; Josef Köck; Sabine MacNelly; Shaotang Ren; Hubert E Blum; Michael Nassal
The tupaia model for the study of hepatitis B virus: direct infection and HBV genome transduction of primary tupaia hepatocytes.
Methods in molecular medicine 2004;96():153-61.
2004: Michael Geissler; Robert Weth; Christian F Grimm; Dörte Ortmann; Hubert E Blum
Induction of anti-hepatitis B virus immune responses through DNA immunization.
Methods in molecular medicine 2004;96():43-54.
2003: Josef Köck; Thomas F Baumert; William E Delaney; Hubert E Blum; Fritz von Weizsäcker
Inhibitory effect of adefovir and lamivudine on the initiation of hepatitis B virus infection in primary tupaia hepatocytes.
Hepatology (Baltimore, Md.) 2003;38(6):1410-8.
2003: Hans Christian Spangenberg; I Zuber-Jerger; Robert Thimme; Hubert E Blum; Fritz von Weizsäcker
[Systemic treatment for hepatocellular carcinoma].
Zentralblatt für Chirurgie 2003;128(11):906-10.
2003: Michael Geissler; Leonhard Mohr; Mona Y Ali; Christian F Grimm; Marcus Ritter; Hubert E Blum
Immunobiology and gene-based immunotherapy of hepatocellular carcinoma.
Zeitschrift für Gastroenterologie 2003;41(11):1101-10.
2003: Heidi Barth; Christiane Schafer; Mohammed I Adah; Fuming Zhang; Robert J Linhardt; Hidenao Toyoda; Akiko Kinoshita-Toyoda; Toshihiko Toida; Toin H van Kuppevelt; Erik Depla; Fritz Von Weizsacker; Hubert E Blum; Thomas F Baumert
Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate.
The Journal of biological chemistry 2003;278(42):41003-12.
2003: Darius Moradpour; Rainer Gosert; Denise Egger; François Penin; Hubert E Blum; Kurt Bienz
Membrane association of hepatitis C virus nonstructural proteins and identification of the membrane alteration that harbors the viral replication complex.
Antiviral research 2003;60(2):103-9.
2003: Hubert E Blum; U T Hopt
[Hepatocellular carcinoma. Pathogenesis and multicentricity].
Der Chirurg; Zeitschrift für alle Gebiete der operativen Medizen 2003;74(8):709-16.
2003: Annette Schmitt-Gräff; Viktoria Ertelt; Hans-Peter Allgaier; Konrad Koelble; Manfred Olschewski; Roland Nitschke; Marie-L Bochaton-Piallat; Giulio Gabbiani; Hubert E Blum
Cellular retinol-binding protein-1 in hepatocellular carcinoma correlates with beta-catenin, Ki-67 index, and patient survival.
Hepatology (Baltimore, Md.) 2003;38(2):470-80.
2003: Josef Kock; Michael Kann; Gerhard Putz; Hubert E Blum; Fritz Von Weizsacker
Central role of a serine phosphorylation site within duck hepatitis B virus core protein for capsid trafficking and genome release.
The Journal of biological chemistry 2003;278(30):28123-9.
2003: Riccardo Lencioni; Hans-Peter Allgaier; Dania Cioni; Manfred Olschewski; Peter Deibert; Laura Crocetti; Holger Frings; Jörg Laubenberger; Ina Zuber; Hubert E Blum; Carlo Bartolozzi
Small hepatocellular carcinoma in cirrhosis: randomized comparison of radio-frequency thermal ablation versus percutaneous ethanol injection.
Radiology 2003;228(1):235-40.
2003: Peter Hasselblatt; Hubert E Blum; Wolf-Bernhard Offensperger
New ways of interfering with HCV replication.
Hepatology (Baltimore, Md.) 2003;37(6):1470-2.
2003: Alex Blindenbacher; Francois H T Duong; Lukas Hunziker; Simone T D Stutvoet; Xueya Wang; Luigi Terracciano; Darius Moradpour; Hubert E Blum; Tonino Alonzi; Marco Tripodi; Nicola La Monica; Markus H Heim
Expression of hepatitis c virus proteins inhibits interferon alpha signaling in the liver of transgenic mice.
Gastroenterology 2003;124(5):1465-75.
2003: Rainer Gosert; Denise Egger; Volker Lohmann; Ralf Bartenschlager; Hubert E Blum; Kurt Bienz; Darius Moradpour
Identification of the hepatitis C virus RNA replication complex in Huh-7 cells harboring subgenomic replicons.
Journal of virology 2003;77(9):5487-92.
2003: Hubert E Blum
Molecular therapy and prevention of hepatocellular carcinoma.
Hepatobiliary & pancreatic diseases international : HBPD INT 2003;2(1):11-22.
2003: Carsten Grüllich; Thomas F Baumert; Hubert E Blum
Acute Mycoplasma pneumoniae infection presenting as cholestatic hepatitis.
Journal of clinical microbiology 2003;41(1):514-5.
2002: Darius Moradpour; Volker Brass; Rainer Gosert; Benno Wölk; Hubert E Blum
[Molecular virology of hepatitis C].
Praxis 2002;91(51-52):2247-53.
2002: Hubert E Blum
[Without cell death there is no life].
Deutsche medizinische Wochenschrift (1946) 2002;127(49):2602-3.
2002: F V Weizsäcker; Hubert E Blum
[Molecular diagnostic tools in gastroenterology].
Praxis 2002;91(49):2139-43.
2002: Hubert E Blum
[Transgenic plants].
Praxis 2002;91(49):2119-24.
2002: Hubert E Blum; Darius Moradpour
Viral pathogenesis of hepatocellular carcinoma.
Journal of gastroenterology and hepatology 2002;17 Suppl 3():S413-20.
2002: Hubert E Blum
Chronic cholestatic liver diseases.
Journal of gastroenterology and hepatology 2002;17 Suppl 3():S399-402.
2002: Hubert E Blum; Darius Moradpour
Antiviral treatment of patients with HBV-related cirrhosis.
Journal of gastroenterology and hepatology 2002;17 Suppl 3():S306-10.
2002: Natalia Ivashkina; Benno Wölk; Volker Lohmann; Ralf Bartenschlager; Hubert E Blum; François Penin; Darius Moradpour
The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment.
Journal of virology 2002;76(24):13088-93.
2002: Robert Thimme; Hans Christian Spangenberg; Fritz von Weizsäcker; Hubert E Blum
[T cell response to hepatitis B and C: from viral elimination to hepatocellular carcinoma].
Deutsche medizinische Wochenschrift (1946) 2002;127(43):2277-9.
2002: Darius Moradpour; Volker Brass; Rainer Gosert; Benno Wölk; Hubert E Blum
Hepatitis C: molecular virology and antiviral targets.
Trends in molecular medicine 2002;8(10):476-82.
2002: Matthes Huesker; Yvonne Folmer; Michaela Schneider; Christine Fulda; Hubert E Blum; Peter Hafkemeyer
Reversal of drug resistance of hepatocellular carcinoma cells by adenoviral delivery of anti-MDR1 ribozymes.
Hepatology (Baltimore, Md.) 2002;36(4 Pt 1):874-84.
2002: Hubert E Blum
[Chronic hepatitis C virus infection: always treat!--Contra].
Deutsche medizinische Wochenschrift (1946) 2002;127(36):1841.
2002: Robert Thimme; Hubert E Blum
[Acute hepatitis C. Therapy with interferon alpha-2b].
Der Internist 2002;43(9):1148-50.
2002: Tilman M Bauer; Henning Schwacha; Bernhard Steinbrückner; Folke E Brinkmann; Anette K Ditzen; John J Aponte; Klaus Pelz; Dieter Berger; Manfred Kist; Hubert E Blum
Small intestinal bacterial overgrowth in human cirrhosis is associated with systemic endotoxemia.
The American journal of gastroenterology 2002;97(9):2364-70.
2002: Hans-Peter Allgaier; Daniel Galandi; Manfred Olschewski; Hubert E Blum
[Nonsurgical therapy of hepatocellular carcinoma].
Praxis 2002;91(35):1387-92.
2002: J Harder; Hubert E Blum
[Cholangiocarcinoma].
Praxis 2002;91(34):1352-6.
2002: C Arnold; Henning Usadel; Hubert E Blum
[Epigenetics: significance for tumor genesis and clinical features].
Deutsche medizinische Wochenschrift (1946) 2002;127(33):1701-3.
2002: Denise Egger; Benno Wölk; Rainer Gosert; Leonardo Bianchi; Hubert E Blum; Darius Moradpour; Kurt Bienz
Expression of hepatitis C virus proteins induces distinct membrane alterations including a candidate viral replication complex.
Journal of virology 2002;76(12):5974-84.
2002: Darius Moradpour; Hubert E Blum
[Therapy of hepatitis C].
Praxis 2002;91(22):977-82.
2002: Kaspar Truninger; Heiko Witt; Josef Köck; Andreas Kage; B Seifert; Rudolf W Ammann; Hubert E Blum; Michael Becker
Mutations of the serine protease inhibitor, Kazal type 1 gene, in patients with idiopathic chronic pancreatitis.
The American journal of gastroenterology 2002;97(5):1133-7.
2002: Claudia Spahn; Bernhard Becker; Kurt Fritzsche; Thorsten Burger; Hubert E Blum; Michael Wirsching
Psychosomatic liaison service in medicine - need for psychotherapeutic interventions and their realisation.
Swiss medical weekly 2002;132(13-14):166-73.
2002: Volker Brass; Elke Bieck; Roland Montserret; Benno Wölk; Jan Albert Hellings; Hubert E Blum; François Penin; Darius Moradpour
An amino-terminal amphipathic alpha-helix mediates membrane association of the hepatitis C virus nonstructural protein 5A.
The Journal of biological chemistry 2002;277(10):8130-9.
2002: L R Kündgen; Christian Thoma; Josef Köck; J Wilting; K Koch; Wolf-Bernhard Offensperger; Hubert E Blum; Fritz von Weizsäcker
Inhibition of duck hepatitis B virus replication by intrahepatic expression of an antiviral resistance gene.
Journal of molecular medicine (Berlin, Germany) 2002;80(3):187-95.
2002: Volker Brass; Hubert E Blum; Darius Moradpour
Of mice and men: a small animal model of hepatitis C virus replication.
Hepatology (Baltimore, Md.) 2002;35(3):722-4.
2002: Leonhard Mohr; Michael Geissler; Hubert E Blum
Gene therapy for malignant liver disease.
Expert opinion on biological therapy 2002;2(2):163-75.
2002: Sabine Wellnitz; Bettina Klumpp; Heidi Barth; Susumu Ito; Erik Depla; Jean Dubuisson; Hubert E Blum; Thomas F Baumert
Binding of hepatitis C virus-like particles derived from infectious clone H77C to defined human cell lines.
Journal of virology 2002;76(3):1181-93.
2002: Darius Moradpour; Elke Bieck; Thomas Hügle; Winfried S Wels; Jim Zhen Wu; Zhi Hong; Hubert E Blum; Ralf Bartenschlager
Functional properties of a monoclonal antibody inhibiting the hepatitis C virus RNA-dependent RNA polymerase.
The Journal of biological chemistry 2002;277(1):593-601.
2002: Hubert E Blum
Molecular targets for prevention of hepatocellular carcinoma.
Digestive diseases (Basel, Switzerland) 2002;20(1):81-90.
2002: Xiping Zhao; Zhen-Ya Tang; Bettina Klumpp; Guido Wolff-Vorbeck; Heidi Barth; Shoshana Levy; Fritz von Weizsäcker; Hubert E Blum; Thomas F Baumert
Primary hepatocytes of Tupaia belangeri as a potential model for hepatitis C virus infection.
The Journal of clinical investigation 2002;109(2):221-32.
2002: Fritz von Weizsäcker; Josef Köck; Stefan Wieland; Jürgen Beck; Michael Nassal; Hubert E Blum
Cis-preferential recruitment of duck hepatitis B virus core protein to the RNA/polymerase preassembly complex.
Hepatology (Baltimore, Md.) 2002;35(1):209-16.
2001: Michael Geissler; Leonhard Mohr; Hubert E Blum
[Immunotherapy of hepatocellular carcinoma].
Deutsche medizinische Wochenschrift (1946) 2001;126(51-52):1464-6.
2001: Tilman M Bauer; Manfred Kist; Franz Daschner; Hubert E Blum
[Nosocomial diarrhea].
Deutsche medizinische Wochenschrift (1946) 2001;126(50):1431-4.
2001: Benno Wölk; Darius Moradpour; Hubert E Blum
[New methods for demonstrating nucleic acids].
Deutsche medizinische Wochenschrift (1946) 2001;126(48):1365-8.
2001: J Schmidt-Mende; Elke Bieck; Thomas Hügle; François Penin; Charles M Rice; Hubert E Blum; Darius Moradpour
Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase.
The Journal of biological chemistry 2001;276(47):44052-63.
2001: C Mauch; C Grimm; S Meckel; Jack R Wands; Hubert E Blum; Michael Roggendorf; Michael Geissler
Induction of cytotoxic T lymphocyte responses against hepatitis delta virus antigens which protect against tumor formation in mice.
Vaccine 2001;20(1-2):170-80.
2001: Kaspar Truninger; Rudolf W Ammann; Hubert E Blum; Heiko Witt
Genetic aspects of chronic pancreatitis: insights into aetiopathogenesis and clinical implications.
Swiss medical weekly 2001;131(39-40):565-74.
2001: Tilman M Bauer; Bernhard Steinbrückner; Folke E Brinkmann; Anette K Ditzen; Henning Schwacha; J J Aponte; Klaus Pelz; Manfred Kist; Hubert E Blum
Small intestinal bacterial overgrowth in patients with cirrhosis: prevalence and relation with spontaneous bacterial peritonitis.
The American journal of gastroenterology 2001;96(10):2962-7.
2001: Christian Thoma; Peter Hasselblatt; Josef Köck; S F Chang; Birgit Hockenjos; H Will; M W Hentze; Hubert E Blum; Fritz von Weizsäcker; Wolf-Bernhard Offensperger
Generation of stable mRNA fragments and translation of N-truncated proteins induced by antisense oligodeoxynucleotides.
Molecular cell 2001;8(4):865-72.
2001: Darius Moradpour; Benno Wölk; Andreas Cerny; M H Heim; Hubert E Blum
Hepatitis C: a concise review.
Minerva medica 2001;92(5):329-39.
2001: Michael Geissler; Leonhard Mohr; Robert Weth; G Köhler; Christian F Grimm; Tim Krohne; Fritz von Weizsäcker; Hubert E Blum
Immunotherapy directed against alpha-fetoprotein results in autoimmune liver disease during liver regeneration in mice.
Gastroenterology 2001;121(4):931-9.
2001: Kaspar Truninger; N Malik; Rudolf W Ammann; Beat Muellhaupt; B Seifert; H J Müller; Hubert E Blum
Mutations of the cystic fibrosis gene in patients with chronic pancreatitis.
The American journal of gastroenterology 2001;96(9):2657-61.
2001: Oliver G Opitz; Yasir Suliman; William C Hahn; Hideki Harada; Hubert E Blum; Anil K Rustgi
Cyclin D1 overexpression and p53 inactivation immortalize primary oral keratinocytes by a telomerase-independent mechanism.
The Journal of clinical investigation 2001;108(5):725-32.
2001: Tim Krohne; Srinivas Shankara; Michael Geissler; B L Roberts; Jack R Wands; Hubert E Blum; Leonhard Mohr
Mechanisms of cell death induced by suicide genes encoding purine nucleoside phosphorylase and thymidine kinase in human hepatocellular carcinoma cells in vitro.
Hepatology (Baltimore, Md.) 2001;34(3):511-8.
2001: Darius Moradpour; Andreas Cerny; M H Heim; Hubert E Blum
Hepatitis C: an update.
Swiss medical weekly 2001;131(21-22):291-8.
2001: Magdalena Robaczewska; Sylviane Guerret; J S Remy; Isabelle Chemin; Wolf-Bernhard Offensperger; Michèle Chevallier; Jean-Paul Behr; Anna J Podhajska; Hubert E Blum; Christian Trepo; Lucyna Cova
Inhibition of hepadnaviral replication by polyethylenimine-based intravenous delivery of antisense phosphodiester oligodeoxynucleotides to the liver.
Gene therapy 2001;8(11):874-81.
2001: Josef Köck; Michael Nassal; S MacNelly; Thomas F Baumert; Hubert E Blum; Fritz von Weizsäcker
Efficient infection of primary tupaia hepatocytes with purified human and woolly monkey hepatitis B virus.
Journal of virology 2001;75(11):5084-9.
2001: Thomas Hügle; Frauke Fehrmann; Elke Bieck; M Kohara; Hans-Georg Kräusslich; Charles M Rice; Hubert E Blum; Darius Moradpour
The hepatitis C virus nonstructural protein 4B is an integral endoplasmic reticulum membrane protein.
Virology 2001;284(1):70-81.
2001: Volker Siegerstetter; Peter Deibert; Andreas Ochs; Manfred Olschewski; Hubert E Blum; Martin Rössle
Treatment of refractory hepatic hydrothorax with transjugular intrahepatic portosystemic shunt: long-term results in 40 patients.
European journal of gastroenterology & hepatology 2001;13(5):529-34.
2001: Darius Moradpour; Benno Grabscheid; Andreas Kammer; Gunter Schmidtke; M Groettrup; Hubert E Blum; Andreas Cerny
Expression of hepatitis C virus proteins does not interfere with major histocompatibility complex class I processing and presentation in vitro.
Hepatology (Baltimore, Md.) 2001;33(5):1282-7.
2001: Leonhard Mohr; SK Yoon; Simon J Eastman; Qiuming Chu; Ronald K Scheule; PP Scaglioni; Michael Geissler; Tobias Heintges; Hubert E Blum; Jack R Wands
Cationic liposome-mediated gene delivery to the liver and to hepatocellular carcinomas in mice.
Human gene therapy 2001;12(7):799-809.
2001: Andrea Kröger; Dörte Ortmann; Tim Krohne; Leonhard Mohr; Hubert E Blum; Hansjörg Hauser; Michael Geissler
Growth suppression of the hepatocellular carcinoma cell line Hepa1-6 by an activatable interferon regulatory factor-1 in mice.
Cancer research 2001;61(6):2609-17.
2001: M Huber; Martin Rössle; Volker Siegerstetter; Andreas Ochs; Klaus Haag; M Kist; Hubert E Blum
Helicobacter pylori infection does not correlate with plasma ammonia concentration and hepatic encephalopathy in patients with cirrhosis.
Hepato-gastroenterology 2001;48(38):541-4.
2001: TH Hauer; G Dziekan; Henning Rüden; Hubert E Blum; Franz Daschner
[Meaningful and meaningless hygienic measures in internal medicine].
Deutsche medizinische Wochenschrift (1946) 2001;126(4):83-8.
2001: Hans-Peter Allgaier; Daniel Galandi; Ina Zuber; Hubert E Blum
Radiofrequency thermal ablation of hepatocellular carcinoma.
Digestive diseases (Basel, Switzerland) 2001;19(4):301-10.
2001: Kaspar Truninger; Josef Köck; H P Wirth; Beat Muellhaupt; C Arnold; Fritz von Weizsäcker; B Seifert; Rudolf W Ammann; Hubert E Blum
Trypsinogen gene mutations in patients with chronic or recurrent acute pancreatitis.
Pancreas 2001;22(1):18-23.
2000: M Geissler; Hubert E Blum
[Therapeutic monoclonal antibodies].
Deutsche medizinische Wochenschrift (1946) 2000;125(49):1501-4.
2000: Darius Moradpour; Hubert E Blum
[DNA vaccination].
Praxis 2000;89(43):1745-8.
2000: Christian F Grimm; Dörte Ortmann; Leonhard Mohr; S Michalak; Tim Krohne; S Meckel; S Eisele; J Encke; Hubert E Blum; Michael Geissler
Mouse alpha-fetoprotein-specific DNA-based immunotherapy of hepatocellular carcinoma leads to tumor regression in mice.
Gastroenterology 2000;119(4):1104-12.
2000: Andreas Ochs; Hans-Peter Allgaier; H Schwacha; Volker Siegerstetter; M Sawatzki; Hubert E Blum
[Pancreatic and biliary tract tumors--diagnosis: ultrasonic diagnosis--endosonography].
Praxis 2000;89(39):1553-8.
2000: Tilman M Bauer; Henning Schwacha; Bernhard Steinbrückner; Folke E Brinkmann; Anette K Ditzen; M Kist; Hubert E Blum
Diagnosis of small intestinal bacterial overgrowth in patients with cirrhosis of the liver: poor performance of the glucose breath hydrogen test.
Journal of hepatology 2000;33(3):382-6.
2000: H Schwacha; Hans-Peter Allgaier; Peter Deibert; Manfred Olschewski; U Allgaier; Hubert E Blum
A sphincterotome-based technique for selective transpapillary common bile duct cannulation.
Gastrointestinal endoscopy 2000;52(3):387-91.
2000: Thomas F Baumert; S Wellnitz; S Aono; J Satoi; David Herion; J Tilman Gerlach; Gerd R Pape; J Y Lau; Jay H Hoofnagle; Hubert E Blum; TSANYANG LIANG
Antibodies against hepatitis C virus-like particles and viral clearance in acute and chronic hepatitis C.
Hepatology (Baltimore, Md.) 2000;32(3):610-7.
2000: Hans-Peter Allgaier; S Rossi; Peter Deibert; Ina Zuber; M Hering; Hubert E Blum
[Hepatocellular carcinoma: percutaneous ethanol injection/transarterial chemoembolization/radiofrequency thermoablation].
Praxis 2000;89(24):1056-60.
2000: Christian Thoma; Stefan Wieland; Darius Moradpour; Fritz von Weizsäcker; S Offensperger; J Madon; Hubert E Blum; Wolf-Bernhard Offensperger
Ligand-mediated retargeting of recombinant adenovirus for gene transfer in vivo.
Gene therapy 2000;7(12):1039-45.
2000: Hans-Peter Allgaier; H Schwacha; Andreas Ochs; Volker Siegerstetter; Hubert E Blum
[Value of manometry].
Praxis 2000;89(22):955-7.
2000: Hans-Peter Allgaier; G Becker; Hubert E Blum
[A therapeutic study of hepatocellular carcinoma using octreotide (HECTOR). Hepatocellular Carcinoma: Treatment with Octreotide].
Deutsche medizinische Wochenschrift (1946) 2000;125(11):320.
2000: Leonhard Mohr; Srinivas Shankara; SK Yoon; Tim Krohne; Michael Geissler; B Roberts; Hubert E Blum; Jack R Wands
Gene therapy of hepatocellular carcinoma in vitro and in vivo in nude mice by adenoviral transfer of the Escherichia coli purine nucleoside phosphorylase gene.
Hepatology (Baltimore, Md.) 2000;31(3):606-14.
2000: Benno Wölk; D Sansonno; Hans-Georg Kräusslich; F Dammacco; Charles M Rice; Hubert E Blum; Darius Moradpour
Subcellular localization, stability, and trans-cleavage competence of the hepatitis C virus NS3-NS4A complex expressed in tetracycline-regulated cell lines.
Journal of virology 2000;74(5):2293-304.
2000: D Moradpour; Hubert E Blum
[Molecular aspects of hepatocellular carcinoma].
Zentralblatt für Chirurgie 2000;125(7):592-6.
2000: K Truninger; Hubert E Blum
[Screening for prevention and early detection of colorectal carcinoma].
Therapeutische Umschau. Revue thérapeutique 2000;57(1):26-32.
2000: Wolf-Bernhard Offensperger; Christian Thoma; Darius Moradpour; Fritz von Weizsäcker; S Offensperger; Hubert E Blum
Antisense oligonucleotide therapy of hepadnavirus infection.
Methods in enzymology 2000;314():524-36.
1999: Hubert E Blum
[Hepatology. Molecular revolution].
Deutsche medizinische Wochenschrift (1946) 1999;124(51-52):1550-2.
1999: Hubert E Blum; D Moradpour
[Gene technology drugs and gene therapy].
Therapeutische Umschau. Revue thérapeutique 1999;56(12):730-7.
1999: D Moradpour; Hubert E Blum
[DNA chip technology].
Deutsche medizinische Wochenschrift (1946) 1999;124(46):1395-6.
1999: Hubert E Blum; D Moradpour
[Gene technology].
Deutsche medizinische Wochenschrift (1946) 1999;124(46):1393-4.
1999: Darius Moradpour; Hubert E Blum
Current and evolving therapies for hepatitis C.
European journal of gastroenterology & hepatology 1999;11(11):1199-202.
1999: Markus H Heim; Darius Moradpour; Hubert E Blum
Expression of hepatitis C virus proteins inhibits signal transduction through the Jak-STAT pathway.
Journal of virology 1999;73(10):8469-75.
1999: Hans-Peter Allgaier; H Schwacha; M Kleinschmidt; R Thimme; Ulrich Schöffel; Hubert E Blum
Ampullary hamartoma: A rare cause of biliary obstruction.
Digestion 1999;60(5):497-500.
1999: Fritz von Weizsäcker; Josef Köck; Stefan Wieland; Wolf-Bernhard Offensperger; Hubert E Blum
Dominant negative mutants of the duck hepatitis B virus core protein interfere with RNA pregenome packaging and viral DNA synthesis.
Hepatology (Baltimore, Md.) 1999;30(1):308-15.
1999: Hans-Peter Allgaier; Peter Deibert; Ina Zuber; Manfred Olschewski; Hubert E Blum
Percutaneous radiofrequency interstitial thermal ablation of small hepatocellular carcinoma.
Lancet 1999;353(9165):1676-7.
1999: Michael Geissler; V Bruss; S Michalak; Birgit Hockenjos; Dörte Ortmann; Wolf-Bernhard Offensperger; Jack R Wands; Hubert E Blum
Intracellular retention of hepatitis B virus surface proteins reduces interleukin-2 augmentation after genetic immunizations.
Journal of virology 1999;73(5):4284-92.
1999: J zu Putlitz; Hubert E Blum
[Intracellular antibodies: a new therapeutic concept for virus infections and neoplasms].
Deutsche medizinische Wochenschrift (1946) 1999;124(12):357-60.
1999: D Moradpour; Hubert E Blum
[Dolly, Polly et al.: cloning by somatic cell nucleus transfer].
Deutsche medizinische Wochenschrift (1946) 1999;124(9):255-6.
1999: Klaus Haag; Martin Rössle; Andreas Ochs; M Huber; Volker Siegerstetter; Manfred Olschewski; E Berger; S Lu; Hubert E Blum
Correlation of duplex sonography findings and portal pressure in 375 patients with portal hypertension.
AJR. American journal of roentgenology 1999;172(3):631-5.
1999: Hubert E Blum
Molecular biology and gene therapy in gastroenterology and hepatology.
European journal of gastroenterology & hepatology 1999;11(1):1-7.
1998: Hans-Peter Allgaier; Peter Deibert; Manfred Olschewski; C Spamer; U Blum; W Gerok; Hubert E Blum
Survival benefit of patients with inoperable hepatocellular carcinoma treated by a combination of transarterial chemoembolization and percutaneous ethanol injection--a single-center analysis including 132 patients.
International journal of cancer. Journal international du cancer 1998;79(6):601-5.
1998: B A Volk-Zeiher; Hubert E Blum
[Therapy of Crohn disease in internal medicine: postoperative recurrence and fistulas].
Praxis 1998;87(48):1657-60.
1998: Isabelle Chemin; Darius Moradpour; Stefan Wieland; Wolf-Bernhard Offensperger; E Walter; Jean-Paul Behr; Hubert E Blum
Liver-directed gene transfer: a linear polyethlenimine derivative mediates highly efficient DNA delivery to primary hepatocytes in vitro and in vivo.
Journal of viral hepatitis 1998;5(6):369-75.
1998: C Arnold; D Moradpour; Hubert E Blum
Tuberculous colitis mimicking Crohn's disease.
The American journal of gastroenterology 1998;93(11):2294-6.
1998: Josef Köck; Stefan Wieland; Hubert E Blum; Fritz von Weizsäcker
Duck hepatitis B virus nucleocapsids formed by N-terminally extended or C-terminally truncated core proteins disintegrate during viral DNA maturation.
Journal of virology 1998;72(11):9116-20.
1998: Hans-Peter Allgaier; Peter Deibert; G Becker; Hubert E Blum
[Hepatocellular carcinoma: npn-surgical treatment].
Praxis 1998;87(44):1466-70.
1998: Hubert E Blum
[Viral hepatitis: molecular diagnosis].
Praxis 1998;87(42):1381-8.
1998: Robert Thimme; Hubert E Blum; Friedemann Weber
[Quorum sensing: a mechanism of communication between bacteria].
Deutsche medizinische Wochenschrift (1946) 1998;123(40):1183-4.
1998: Hubert E Blum
[Indications for combination interferon-ribavirin therapy in chronic hepatitis C].
Der Internist 1998;39(9):981.
1998: J zu Putlitz; S Wieland; Hubert E Blum; Jack R Wands
Antisense RNA complementary to hepatitis B virus specifically inhibits viral replication.
Gastroenterology 1998;115(3):702-13.
1998: Robert Thimme; Hubert E Blum
[T-cell response against viruses. A new non-cytotoxic antiviral strategy].
Deutsche medizinische Wochenschrift (1946) 1998;123(34-35):1007-8.
1998: Darius Moradpour; C Englert; Hubert E Blum
Independent regulation of two separate gene activities in a continuous human cell line.
Biological chemistry 1998;379(8-9):1189-91.
1998: Peter Deibert; S Schwarz; Manfred Olschewski; Volker Siegerstetter; Hubert E Blum; Martin Rössle
Risk factors and prevention of early infection after implantation or revision of transjugular intrahepatic portosystemic shunts: results of a randomized study.
Digestive diseases and sciences 1998;43(8):1708-13.
1998: L T Heuss; M H Heim; Ursula Schultz; D Wissmann; Wolf-Bernhard Offensperger; Peter Staeheli; Hubert E Blum
Biological efficacy and signal transduction through STAT proteins of recombinant duck interferon in duck hepatitis B virus infection.
The Journal of general virology 1998;79 ( Pt 8)():2007-12.
1998: Hans-Peter Allgaier; Peter Deibert; Ina Zuber; Hubert E Blum
[Percutaneous treatment of liver tumors using interstitial radiofrequency thermoablation. A new therapeutic strategy].
Deutsche medizinische Wochenschrift (1946) 1998;123(30):907-11.
1998: Michael Geissler; R Schirmbeck; J Reimann; Hubert E Blum; Jack R Wands
Cytokine and hepatitis B virus DNA co-immunizations enhance cellular and humoral immune responses to the middle but not to the large hepatitis B virus surface antigen in mice.
Hepatology (Baltimore, Md.) 1998;28(1):202-10.
1998: Darius Moradpour; P Kary; Charles M Rice; Hubert E Blum
Continuous human cell lines inducibly expressing hepatitis C virus structural and nonstructural proteins.
Hepatology (Baltimore, Md.) 1998;28(1):192-201.
1998: Darius Moradpour; T Wakita; J R Wands; Hubert E Blum
Tightly regulated expression of the entire hepatitis C virus structural region in continuous human cell lines.
Biochemical and biophysical research communications 1998;246(3):920-4.
1998: Wolf-Bernhard Offensperger; S Offensperger; Hubert E Blum
Antisense therapy of hepatitis B virus infection.
Molecular biotechnology 1998;9(2):161-70.
1998: Hans-Peter Allgaier; K Haag; Hubert E Blum
[Hepatopulmonary syndrome].
Zeitschrift für Gastroenterologie 1998;36(3):247-51.
1998: Darius Moradpour; Hubert E Blum
[Clinical significance of hepatitis B virus mutants].
Praxis 1998;87(6):205-9.
1997: J zu Putlitz; E A Roberts; S Wieland; Y Kono; Hubert E Blum
Hepatitis B virus replication and viral antigen synthesis in hepatocyte lines derived from normal human liver.
Virus research 1997;52(2):177-82.
1997: Robert Thimme; Hubert E Blum; Friedemann Weber
[Kaposi sarcoma: a virus-induced tumor?].
Deutsche medizinische Wochenschrift (1946) 1997;122(43):1323-6.
1997: Jack R Wands; Michael Geissler; J Z Putlitz; Hubert E Blum; Fritz von Weizsäcker; Leonhard Mohr; SK Yoon; M Melegari; PP Scaglioni
Nucleic acid-based antiviral and gene therapy of chronic hepatitis B infection.
Journal of gastroenterology and hepatology 1997;12(9-10):S354-69.
1997: Hubert E Blum
[Colon carcinoma: molecular diagnosis and therapy].
Praxis 1997;86(39):1504-9.
1997: C Arnold; Klaus Haag; Hubert E Blum; Martin Rössle
Acute hemoperitoneum after large-volume paracentesis.
Gastroenterology 1997;113(3):978-82.
1997: Fritz von Weizsäcker; Stefan Wieland; Josef Köck; Wolf-Bernhard Offensperger; S Offensperger; Darius Moradpour; Hubert E Blum
Gene therapy for chronic viral hepatitis: ribozymes, antisense oligonucleotides, and dominant negative mutants.
Hepatology (Baltimore, Md.) 1997;26(2):251-5.
1997: Hubert E Blum
[Molecular biology 1996: gastroenterology and hepatology].
Praxis 1997;86(29-30):1172-7.
1997: Hubert E Blum
[Whipple's disease: molecular biology--clinical aspects--therapy].
Praxis 1997;86(29-30):1143-6.
1997: Hubert E Blum; Darius Moradpour; F vøn Weizsäcker; S Wieland; T Peters; J W Rasenack
[Hepatitis B virus mutants--clinical significance].
Zeitschrift für Gastroenterologie 1997;35(5):347-55.
1997: Martin Rössle; Peter Deibert; Klaus Haag; Andreas Ochs; Manfred Olschewski; Volker Siegerstetter; K H Hauenstein; R Geiger; C Stiepak; W Keller; Hubert E Blum
Randomised trial of transjugular-intrahepatic-portosystemic shunt versus endoscopy plus propranolol for prevention of variceal rebleeding.
Lancet 1997;349(9058):1043-9.
1997: Darius Moradpour; Robert Thimme; Hubert E Blum
[Molecular biology in internal medicine. Report of the 24th Ludwig Heilmeyer Symposium of the Society for Progress in Internal Medicine].
Deutsche medizinische Wochenschrift (1946) 1997;122(10):309-12.
1997: Hans-Peter Allgaier; Peter Deibert; Hubert E Blum
[Nonsurgical therapy of focal liver lesions].
Praxis 1997;86(4):86-90.
1997: Hubert E Blum
Hepatitis viruses: genetic variants and clinical significance.
International journal of clinical & laboratory research 1997;27(4):213-24.
1997: Hubert E Blum
Update hepatitis A-G.
Digestion 1997;58 Suppl 1():33-6.
1997: Hubert E Blum; Stefan Wieland; Fritz von Weizsäcker
Gene therapy: basic concepts and applications in gastrointestinal diseases.
Digestion 1997;58(2):87-97.
1996: Darius Moradpour; Hubert E Blum
[Hepatitis C, diagnosis and therapy].
Medizinische Klinik (Munich, Germany : 1983) 1996;91(12):769-70.
1996: Stefan Wieland; Fritz von Weizsäcker; Hubert E Blum
[Diagnosis of BSE and Creutzfeldt-Jakob disease].
Deutsche medizinische Wochenschrift (1946) 1996;121(47):1482.
1996: Hubert E Blum
[Current diagnosis of viral hepatitis].
Praxis 1996;85(47):1502-6.
1996: Hans-Peter Allgaier; Peter Deibert; U Blum; H C Spangenberg; E Moser; Hubert E Blum
[Therapy of hepatocellular carcinoma].
Schweizerische medizinische Wochenschrift 1996;126(46):1984-94.
1996: Hans-Peter Allgaier; U Blum; Peter Deibert; H C Spangenberg; Hubert E Blum
[Diagnosis of hepatocellular carcinoma].
Schweizerische medizinische Wochenschrift 1996;126(46):1975-83.
1996: Hans-Peter Allgaier; U Blum; Klaus Haag; P Flügel; H Schwacha; Mathias Langer; Hubert E Blum
[Hemosuccus pancreaticus--a rare cause of upper gastrointestinal bleeding. Successful treatment in two cases by radiologic-interventional embolization of the splenic artery].
Deutsche medizinische Wochenschrift (1946) 1996;121(38):1158-62.
1996: J Madon; Hubert E Blum
Receptor-mediated delivery of hepatitis B virus DNA and antisense oligodeoxynucleotides to avian liver cells.
Hepatology (Baltimore, Md.) 1996;24(3):474-81.
1996: Wolf-Bernhard Offensperger; S Offensperger; A Keppler-Hafkemeyer; P Hafkemeyer; Hubert E Blum
Antiviral activities of penciclovir and famciclovir on duck hepatitis B virus in vitro and in vivo.
Antiviral therapy 1996;1(3):141-6.
1996: Fritz von Weizsäcker; Stefan Wieland; Hubert E Blum
Inhibition of viral replication by genetically engineered mutants of the duck hepatitis B virus core protein.
Hepatology (Baltimore, Md.) 1996;24(2):294-9.
1996: Stefan Wieland; Fritz von Weizsäcker; Hubert E Blum
[Prions].
Deutsche medizinische Wochenschrift (1946) 1996;121(30):949-52.
1996: E Walter; R Keist; B Niederöst; I Pult; Hubert E Blum
Hepatitis B virus infection of tupaia hepatocytes in vitro and in vivo.
Hepatology (Baltimore, Md.) 1996;24(1):1-5.
1996: P Hafkemeyer; A Keppler-Hafkemeyer; M A al Haya; MJ von Janta-Lipinski; Eckart Matthes; C Lehmann; Wolf-Bernhard Offensperger; S Offensperger; W Gerok; Hubert E Blum
Inhibition of duck hepatitis B virus replication by 2',3'-dideoxy-3'-fluoroguanosine in vitro and in vivo.
Antimicrobial agents and chemotherapy 1996;40(3):792-4.
1996: Martin Rössle; Klaus Haag; Hubert E Blum
The transjugular intrahepatic portosystemic stent-shunt: a review of the literature and own experiences.
Journal of gastroenterology and hepatology 1996;11(3):293-8.
1996: Wolf-Bernhard Offensperger; S Offensperger; Hubert E Blum
Antisense therapy of hepatitis B virus infection : in vivo analyses in the duck hepatitis B virus model.
Methods in molecular medicine 1996;1():143-58.
1995: Hans-Peter Allgaier; Andreas Ochs; Klaus Haag; K H Hauenstein; W Tittor; Martin Rössle; Hubert E Blum
[Recurrent bleeding from colonic varices in portal hypertension. The successful prevention of recurrence by the implantation of a transjugular intrahepatic stent-shunt (TIPS)].
Deutsche medizinische Wochenschrift (1946) 1995;120(51-52):1773-6.
1995: Hubert E Blum; Christa Meyenberger
[Esophageal varices bleeding: causes and pathophysiology].
Praxis 1995;84(51-52):1534-5.
1995: Hubert E Blum; Christa Meyenberger
[Current therapy of esophageal varices hemorrhage].
Praxis 1995;84(51-52):1532-3.
1995: U Blum; Martin Rössle; Klaus Haag; Andreas Ochs; Hubert E Blum; K H Hauenstein; F Astinet; Mathias Langer
Budd-Chiari syndrome: technical, hemodynamic, and clinical results of treatment with transjugular intrahepatic portosystemic shunt.
Radiology 1995;197(3):805-11.
1995: Hubert E Blum
Colorectal cancer: future population screening for early colorectal cancer.
European journal of cancer (Oxford, England : 1990) 1995;31A(7-8):1369-72.
1995: Andreas Ochs; Martin Rössle; Klaus Haag; K H Hauenstein; Peter Deibert; Volker Siegerstetter; Martin Huonker; M Langer; Hubert E Blum
The transjugular intrahepatic portosystemic stent-shunt procedure for refractory ascites.
The New England journal of medicine 1995;332(18):1192-7.
1995: Fritz von Weizsäcker; Stefan Wieland; Hubert E Blum
Identification of two separable modules in the duck hepatitis B virus core protein.
Journal of virology 1995;69(4):2704-7.
1995: Hubert E Blum; K P Maier; G Strohmeyer
[Current therapy for chronic viral hepatitis. The Viral Hepatitis Panel].
Deutsche medizinische Wochenschrift (1946) 1995;120(9):295-300.
1995: Hubert E Blum
[Current diagnosis of viral hepatitis].
Deutsche medizinische Wochenschrift (1946) 1995;120(8):259-62.
1995: Hubert E Blum
[Gene therapy: medical and methodological aspects].
Praxis 1995;84(2):47-9.
1995: Hubert E Blum
[Gene therapy--basic principles].
Praxis 1995;84(2):34-8.
1995: Wolf-Bernhard Offensperger; Hubert E Blum; W Gerok
Therapy of hepadnavirus infection using antisense oligonucleotides.
Intervirology 1995;38(1-2):113-9.
1995: Hubert E Blum
Variants of hepatitis B, C and D viruses: molecular biology and clinical significance.
Digestion 1995;56(2):85-95.
1994: Wolf-Bernhard Offensperger; Hubert E Blum; W Gerok
Molecular therapeutic strategies in hepatitis B virus infection.
The Clinical investigator 1994;72(10):737-41.
1994: Hubert E Blum
[Elevated liver enzymes of unknown etiology].
Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis 1994;83(36):1011-3.
1994: Hubert E Blum
[Hepatitis B and C virus mutants--clinical relevance].
Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis 1994;83(36):1000-4.
1994: Hubert E Blum
[Viral hepatitis A to E--diagnosis, clinical aspects and therapy].
Therapeutische Umschau. Revue thérapeutique 1994;51(8):530-7.
1994: F Lammer; Christa Meyenberger; Hubert E Blum
[Therapy and prevention of esophageal varices hemorrhage: current status].
Schweizerische medizinische Wochenschrift 1994;124(23):1024-33.
1994: H P Wirth; Christa Meyenberger; R Ammann; Hubert E Blum
[Parietal cell antibodies in primary biliary cirrhosis: pathogenetic or diagnostic significance?].
Schweizerische medizinische Wochenschrift 1994;124(19):816-20.
1994: H P Wirth; Christa Meyenberger; J Altorfer; R Ammann; Hubert E Blum
[Eosinophilia in primary biliary cirrhosis: regression under therapy with ursodeoxycholic acid].
Schweizerische medizinische Wochenschrift 1994;124(19):810-5.
1994: Fritz von Weizsäcker; Hubert E Blum; Jack R Wands
Polymerase chain reaction analysis of hepatitis B virus DNA in formalin-fixed, paraffin-embedded liver biopsies from alcoholics using a simplified and standardized amplification protocol.
Journal of hepatology 1994;20(5):646-9.
1994: Hubert E Blum
[Hepatitis B and C: biology and molecular diagnosis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():94-103.
1993: H P Wirth; C Casanova; Christa Meyenberger; B Hammer; R Ammann; Hubert E Blum
[Hepatosplenic schistosomiasis: case report and clinical review].
Schweizerische medizinische Wochenschrift 1993;123(42):1991-5.
1993: G Mang; E Walter; P Bertschinger; F Lammer; Hubert E Blum
[Bacterial infections following sclerosing therapy for esophageal varices].
Schweizerische medizinische Wochenschrift 1993;123(38):1796-801.
1993: E Walter; J Muntwyler; P Bertschinger; Renata Flury; Andreas Ochs; Klaus Haag; Martin Rössle; Hubert E Blum
[Trans-jugular intrahepatic portosystemic stent-shunt (TIPS) in a patient with Budd-Chiari syndrome].
Schweizerische medizinische Wochenschrift 1993;123(36):1696-702.
1993: Wolf-Bernhard Offensperger; S Offensperger; E Walter; Hubert E Blum; W Gerok
Suramin prevents duck hepatitis B virus infection in vivo.
Antimicrobial agents and chemotherapy 1993;37(7):1539-42.
1993: Hubert E Blum
[Chronic viral hepatitis: current diagnosis and therapy].
Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis 1993;82(17):501-5.
1993: Wolf-Bernhard Offensperger; S Offensperger; E Walter; K Teubner; Gabor L Igloi; Hubert E Blum; W Gerok
In vivo inhibition of duck hepatitis B virus replication and gene expression by phosphorothioate modified antisense oligodeoxynucleotides.
The EMBO journal 1993;12(3):1257-62.
1992: Fritz von Weizsäcker; Hubert E Blum; Jack R Wands
Cleavage of hepatitis B virus RNA by three ribozymes transcribed from a single DNA template.
Biochemical and biophysical research communications 1992;189(2):743-8.
1992: Hubert E Blum
[Nobel prize for medicine, 1992].
Deutsche medizinische Wochenschrift (1946) 1992;117(50):1935-8.
1992: Jack R Wands; TSANYANG LIANG; Hubert E Blum; David A Shafritz
Molecular pathogenesis of liver disease during persistent hepatitis B virus infection.
Seminars in liver disease 1992;12(3):252-64.
1992: Hubert E Blum; E Walter
[Hepatitis A to E: current diagnosis].
Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis 1992;81(24):788-90.
1992: Hubert E Blum; E Walter
[Early diagnosis of hepatocellular carcinoma].
Schweizerische Rundschau für Medizin Praxis = Revue suisse de médecine Praxis 1992;81(24):809-10.
1992: Hubert E Blum; Z S Zhang; E Galun; Fritz von Weizsäcker; B Garner; TSANYANG LIANG; Jack R Wands
Hepatitis B virus X protein is not central to the viral life cycle in vitro.
Journal of virology 1992;66(2):1223-7.
1992: E Galun; Wolf-Bernhard Offensperger; Fritz von Weizsäcker; S Offensperger; Jack R Wands; Hubert E Blum
Human non-hepatocytes support hepadnaviral replication and virion production.
The Journal of general virology 1992;73 ( Pt 1)():173-8.
1991: Hubert E Blum
[Liver biopsy].
Deutsche medizinische Wochenschrift (1946) 1991;116(50):1933.
1991: Wolf-Bernhard Offensperger; S Offensperger; E Walter; Hubert E Blum; W Gerok
Sulfated polyanions do not inhibit duck hepatitis B virus infection.
Antimicrobial agents and chemotherapy 1991;35(11):2431-3.
1991: Hubert E Blum; TSANYANG LIANG; E Galun; Jack R Wands
Persistence of hepatitis B viral DNA after serological recovery from hepatitis B virus infection.
Hepatology (Baltimore, Md.) 1991;14(1):56-63.
1991: Wolf-Bernhard Offensperger; S Offensperger; E Walter; Hubert E Blum; W Gerok
Inhibition of duck hepatitis B virus infection by lysosomotropic agents.
Virology 1991;183(1):415-8.
1991: TSANYANG LIANG; Yaacov Baruch; E Ben-Porath; R Enat; Lucyna Bassan; N V Brown; Nurit Rimon; Hubert E Blum; Jack R Wands
Hepatitis B virus infection in patients with idiopathic liver disease.
Hepatology (Baltimore, Md.) 1991;13(6):1044-51.
1991: W Gerok; Hubert E Blum; Wolf-Bernhard Offensperger; S Offensperger; T Andus; V Gross; P C Heinrich
[Hepatology. New research results in its significance for the understanding of liver diseases].
Die Naturwissenschaften 1991;78(6):241-9.
1991: Hubert E Blum; E Galun; Fritz von Weizsäcker; J R Wands
Inhibition of hepatitis B virus by antisense oligodeoxynucleotides.
Lancet 1991;337(8751):1230.
1991: Hubert E Blum; Fritz von Weizsäcker
[The HBsAG negative, anti-HBc/anti-HBS positive patient].
Der Internist 1991;32(5):262-6.
1991: Hubert E Blum; Fritz von Weizsäcker
[Rational clinico-chemical diagnosis of hepatobiliary diseases].
Der Internist 1991;32(5):239-43.
1991: Hubert E Blum; E Galun; TSANYANG LIANG; Fritz von Weizsäcker; Jack R Wands
Naturally occurring missense mutation in the polymerase gene terminating hepatitis B virus replication.
Journal of virology 1991;65(4):1836-42.
1991: E Walter; K Teubner; Hubert E Blum; Wolf-Bernhard Offensperger; S Offensperger; W Gerok
Duck hepatitis B virus infection of non-hepatocytes.
Liver 1991;11(1):53-62.
1991: Fritz von Weizsäcker; S Labeit; H K Koch; W Oehlert; W Gerok; Hubert E Blum
A simple and rapid method for the detection of RNA in formalin-fixed, paraffin-embedded tissues by PCR amplification.
Biochemical and biophysical research communications 1991;174(1):176-80.
1990: F Mattes; Shuping Tong; K Teubner; Hubert E Blum
Complete nucleotide sequence of a German duck hepatitis B virus.
Nucleic acids research 1990;18(20):6140.
1990: Shuping Tong; F Mattes; K Teubner; Hubert E Blum
Complete nucleotide sequence of a Chinese duck hepatitis B virus.
Nucleic acids research 1990;18(20):6139.
1990: Hubert E Blum
[Therapy of chronic hepatitis].
Deutsche medizinische Wochenschrift (1946) 1990;115(38):1438-41.
1990: Hubert E Blum
[The diagnosis of chronic hepatitis].
Deutsche medizinische Wochenschrift (1946) 1990;115(37):1400-3.
1990: TSANYANG LIANG; Hubert E Blum; Jack R Wands
Characterization and biological properties of a hepatitis B virus isolated from a patient without hepatitis B virus serologic markers.
Hepatology (Baltimore, Md.) 1990;12(2):204-12.
1990: P Meier; E Walter; Hubert E Blum; Wolf-Bernhard Offensperger; S Offensperger; M Schmid; W Gerok
[Chronic hepatitis B: diagnostic value of hepatitis-B-virus DNA analysis in serum and liver tissue].
Schweizerische medizinische Wochenschrift 1990;120(9):310-3.
1989: K Oexle; Hubert E Blum; E Walter; Wolf-Bernhard Offensperger; S Offensperger; HJ Grundmann; K Teubner; W Gerok
Duck hepatitis B virus: cloning and subcloning of the viral genome.
Zentralblatt für Bakteriologie, Mikrobiologie, und Hygiene. Series A, Medical microbiology, infectious diseases, virology, parasitology 1989;270(3):424-33.
1988: Hubert E Blum; Wolf-Bernhard Offensperger; E Walter; S Offensperger; W Gerok
Latent hepatitis B virus infection with full-length viral genome in a patient serologically immune to hepatitis B virus infection.
Liver 1988;8(5):307-16.
1988: E Walter; Hubert E Blum; P Meier; Martin Huonker; M Schmid; K P Maier; Wolf-Bernhard Offensperger; S Offensperger; W Gerok
Hepatocellular carcinoma in alcoholic liver disease: no evidence for a pathogenetic role of hepatitis B virus infection.
Hepatology (Baltimore, Md.) 1988;8(4):745-8.
1988: Wolf-Bernhard Offensperger; E Walter; S Offensperger; C Zeschnigk; Hubert E Blum; W Gerok
Duck hepatitis B virus: DNA polymerase and reverse transcriptase activities of replicative complexes isolated from liver and their inhibition in vitro.
Virology 1988;164(1):48-54.
1987: E Walter; Hubert E Blum; Wolf-Bernhard Offensperger; C Zeschnigk; S Offensperger; W Gerok
Spot-blot hybridization assay for the detection of hepatitis B virus DNA in serum: factors determining its sensitivity and specificity.
Hepatology (Baltimore, Md.) 1987;7(3):557-62.