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Kazuro Shiomi

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Masaki Wakasugi; Tsuyoshi Yamamoto; Hiroaki Gouda; Tomoyasu Hirose; Satoshi Omura; Kazuro Shiomi; Akihiro Sugawara; Toshiaki Sunazuka; Shuichi Hirono
Human acidic mammalian chitinase as a novel target for anti-asthma drug design using in silico screening.
Takahiro Ishii; Rokuro Masuma; Kenichi Nonaka; Takuya Suga; Satoshi Omura; Kazuro Shiomi
Cytosporone S with antimicrobial activity, isolated from the fungus Trichoderma sp. FKI-6626.
Takuya Suga; Tsuyoshi Yamamoto; Hideaki Hanaki; Takahiro Ishii; Masato Iwatsuki; Rokuro Masuma; Hidehito Matsui; Kenichi Nonaka; Satoshi Omura; Kazuro Shiomi
Aranorosin circumvents arbekacin-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2″).

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2013: Masaki Wakasugi; Tsuyoshi Yamamoto; Hiroaki Gouda; Tomoyasu Hirose; Satoshi Omura; Kazuro Shiomi; Akihiro Sugawara; Toshiaki Sunazuka; Shuichi Hirono
Human acidic mammalian chitinase as a novel target for anti-asthma drug design using in silico screening.
Bioorganic & medicinal chemistry 2013;21(11):3214-20.
2013: Takahiro Ishii; Rokuro Masuma; Kenichi Nonaka; Takuya Suga; Satoshi Omura; Kazuro Shiomi
Cytosporone S with antimicrobial activity, isolated from the fungus Trichoderma sp. FKI-6626.
Bioorganic & medicinal chemistry letters 2013;23(3):679-81.
2012: Takuya Suga; Tsuyoshi Yamamoto; Hideaki Hanaki; Takahiro Ishii; Masato Iwatsuki; Rokuro Masuma; Hidehito Matsui; Kenichi Nonaka; Satoshi Omura; Kazuro Shiomi
Aranorosin circumvents arbekacin-resistance in MRSA by inhibiting the bifunctional enzyme AAC(6')/APH(2″).
The Journal of antibiotics 2012;65(10):527-9.
2012: Junko Hashida; Aki Ishiyama; Masato Iwatsuki; Atsuko Matsumoto; Mihoko Mori; Miyuki Namatame; Megumi Niitsuma; Aki Nishihara-Tsukashima; Kazuhiko Otoguro; Kazuro Shiomi; Yoko Takahashi; Haruki Yamada; Ismet Ara; Satoshi Omura
Panowamycins A and B, new antitrypanosomal isochromans produced by Streptomyces sp. K07-0010.
The Journal of antibiotics 2012;65(4):197-202.
2012: Masaki Ohtawa; Satoshi Omura; Kazuro Shiomi; Kouhei Sugiyama; Tohru Hiura; Shujiro Izawa; Tohru Nagamitsu
Stereoselective total synthesis of atpenins a4 and b, harzianopyridone, and NBRI23477 B.
Chemical & pharmaceutical bulletin 2012;60(7):898-906.
2011: Yuki Inahashi; Masato Iwatsuki; Aki Ishiyama; Miyuki Namatame; Aki Nishihara-Tsukashima; Atsuko Matsumoto; Tomoyasu Hirose; Toshiaki Sunazuka; Haruki Yamada; Kazuhiko Otoguro; Yoko Takahashi; Satoshi Omura; Kazuro Shiomi
Spoxazomicins A-C, novel antitrypanosomal alkaloids produced by an endophytic actinomycete, Streptosporangium oxazolinicum K07-0460(T).
The Journal of antibiotics 2011;64(4):303-7.
2011: Kyota Kimura; Masato Iwatsuki; Takeshi Nagai; Atsuko Matsumoto; Yoko Takahashi; Kazuro Shiomi; Satoshi Omura; Akio Abe
A small-molecule inhibitor of the bacterial type III secretion system protects against in vivo infection with Citrobacter rodentium.
The Journal of antibiotics 2011;64(2):197-203.
2011: Masato Iwatsuki; Shohei Takada; Mihoko Mori; Aki Ishiyama; Miyuki Namatame; Aki Nishihara-Tsukashima; Kenichi Nonaka; Rokuro Masuma; Kazuhiko Otoguro; Kazuro Shiomi; Satoshi Omura
In vitro and in vivo antimalarial activity of puberulic acid and its new analogs, viticolins A-C, produced by Penicillium sp. FKI-4410.
The Journal of antibiotics 2011;64(2):183-8.
2010: Megumi Niitsuma; Junko Hashida; Masato Iwatsuki; Mihoko Mori; Aki Ishiyama; Miyuki Namatame; Aki Nishihara-Tsukashima; Atsuko Matsumoto; Yoko Takahashi; Haruki Yamada; Kazuhiko Otoguro; Kazuro Shiomi; Satoshi Omura
Sinefungin VA and dehydrosinefungin V, new antitrypanosomal antibiotics produced by Streptomyces sp. K05-0178.
The Journal of antibiotics 2010;63(11):673-9.
2010: Shinsuke Ikeda; Hideaki Hanaki; Chie Yanagisawa; Yurika Ikeda-Dantsuji; Hidehito Matsui; Masato Iwatsuki; Kazuro Shiomi; Taiji Nakae; Keisuke Sunakawa; Satoshi Omura
Identification of the active component that induces vancomycin resistance in MRSA.
The Journal of antibiotics 2010;63(9):533-8.
2010: Junko Hashida; Megumi Niitsuma; Masato Iwatsuki; Mihoko Mori; Aki Ishiyama; Miyuki Namatame; Aki Nishihara-Tsukashima; Kenichi Nonaka; Hideaki Ui; Rokuro Masuma; Kazuhiko Otoguro; Haruki Yamada; Kazuro Shiomi; Satoshi Omura
Pyrenocine I, a new pyrenocine analog produced by Paecilomyces sp. FKI-3573.
The Journal of antibiotics 2010;63(9):559-61.
2010: Hiroaki Gouda; Toshiaki Sunazuka; Tomoyasu Hirose; Kanami Iguchi; Noriyuki Yamaotsu; Akihiro Sugawara; Yoshihiko Noguchi; Yoshifumi Saito; Tsuyoshi Yamamoto; Takeshi Watanabe; Kazuro Shiomi; Satoshi Omura; Shuichi Hirono
NMR spectroscopy and computational analysis of interaction between Serratia marcescens chitinase B and a dipeptide derived from natural-product cyclopentapeptide chitinase inhibitor argifin.
Bioorganic & medicinal chemistry 2010;18(16):5835-44.
2010: Masato Iwatsuki; Yuta Kinoshita; Megumi Niitsuma; Junko Hashida; Mihoko Mori; Aki Ishiyama; Miyuki Namatame; Aki Nishihara-Tsukashima; Kenichi Nonaka; Rokuro Masuma; Kazuhiko Otoguro; Haruki Yamada; Kazuro Shiomi; Satoshi Omura
Antitrypanosomal peptaibiotics, trichosporins B-VIIa and B-VIIb, produced by Trichoderma polysporum FKI-4452.
The Journal of antibiotics 2010;63(6):331-3.
2010: Kazuro Shiomi; Ryosuke Matsui; Atsuo Kakei; Yuichi Yamaguchi; Rokuro Masuma; Hiroko Hatano; Noriko Arai; Miki Isozaki; Haruo Tanaka; Susumu Kobayashi; Andreas Turberg; Satoshi Omura
Verticilide, a new ryanodine-binding inhibitor, produced by Verticillium sp. FKI-1033.
The Journal of antibiotics 2010;63(2):77-82.
2009: Tatsushi Mogi; Yoshiro Murase; Mihoko Mori; Kazuro Shiomi; Satoshi Omura; Madhavi P Paranagama; Kiyoshi Kita
Polymyxin B identified as an inhibitor of alternative NADH dehydrogenase and malate: quinone oxidoreductase from the Gram-positive bacterium Mycobacterium smegmatis.
Journal of biochemistry 2009;146(4):491-9.
2009: Hiroaki Gouda; Shinichi Terashima; Kanami Iguchi; Akihiro Sugawara; Yoshifumi Saito; Tsuyoshi Yamamoto; Tomoyasu Hirose; Kazuro Shiomi; Toshiaki Sunazuka; Satoshi Omura; Shuichi Hirono
Molecular modeling of human acidic mammalian chitinase in complex with the natural-product cyclopentapeptide chitinase inhibitor argifin.
Bioorganic & medicinal chemistry 2009;17(17):6270-8.
2009: Tatsushi Mogi; T Kawakami; Hiroyuki Arai; Yasuo Igarashi; Kazunobu Matsushita; Mihoko Mori; Kazuro Shiomi; Satoshi Omura; Shigeharu Harada; Kiyoshi Kita
Siccanin rediscovered as a species-selective succinate dehydrogenase inhibitor.
Journal of biochemistry 2009;146(3):383-7.
2009: Tatsushi Mogi; Yoshitaka Ano; Tomoko Nakatsuka; Hirohide Toyama; Atsushi Muroi; Hideto Miyoshi; Catharina T Migita; Hideaki Ui; Kazuro Shiomi; Satoshi Omura; Kiyoshi Kita; Kazunobu Matsushita
Biochemical and spectroscopic properties of cyanide-insensitive quinol oxidase from Gluconobacter oxydans.
Journal of biochemistry 2009;146(2):263-71.
2009: Tomoyasu Hirose; Toshiaki Sunazuka; Akihiro Sugawara; Ayako Endo; Kanami Iguchi; Tsuyoshi Yamamoto; Hideaki Ui; Kazuro Shiomi; Takeshi Watanabe; K Barry Sharpless; Satoshi Omura
Chitinase inhibitors: extraction of the active framework from natural argifin and use of in situ click chemistry.
The Journal of antibiotics 2009;62(5):277-82.
2009: Tatsushi Mogi; Hideaki Ui; Kazuro Shiomi; Satoshi Omura; Hideto Miyoshi; Kiyoshi Kita
Antibiotics LL-Z1272 identified as novel inhibitors discriminating bacterial and mitochondrial quinol oxidases.
Biochimica et biophysica acta 2009;1787(2):129-33.
2009: T Mogi; Kazunobu Matsushita; Yoshiro Murase; Kenji Kawahara; Hideto Miyoshi; Hideaki Ui; Kazuro Shiomi; Satoshi Omura; Kiyoshi Kita
Identification of new inhibitors for alternative NADH dehydrogenase (NDH-II).
FEMS microbiology letters 2009;291(2):157-61.
2008: T Mogi; Hideaki Ui; Kazuro Shiomi; Satoshi Omura; Kiyoshi Kita
Gramicidin S identified as a potent inhibitor for cytochrome bd-type quinol oxidase.
FEBS letters 2008;582(15):2299-302.
2008: Atsushi Fukumoto; Yong-Pil Kim; Hideaki Hanaki; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Cyslabdan, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Streptomyces sp. K04-0144. II. Biological activities.
The Journal of antibiotics 2008;61(1):7-10.
2008: Atsushi Fukumoto; Yong-Pil Kim; Atsuko Matsumoto; Yoko Takahashi; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Cyslabdan, a new potentiator of imipenem activity against methicillin-resistant Staphylococcus aureus, produced by Streptomyces sp. K04-0144. I. Taxonomy, fermentation, isolation and structural elucidation.
The Journal of antibiotics 2008;61(1):1-6.
2007: Kazuro Shiomi; Hiroko Hatano; Hiromi Morimoto; Hideaki Ui; Kimitoshi Sakamoto; Kiyoshi Kita; Hiroshi Tomoda; Eun Woo Lee; Tae-Ryeon Heo; Hirokazu Kawagishi; Satoshi Omura
Decursin and decursinol angelate selectively inhibit NADH-fumarate reductase of Ascaris suum.
Planta medica 2007;73(14):1478-81.
2007: Kiyoshi Kita; Kazuro Shiomi; Satoshi Omura
Advances in drug discovery and biochemical studies.
Trends in parasitology 2007;23(5):223-9.
2007: Hideaki Ui; Aki Ishiyama; Hitomi Sekiguchi; Miyuki Namatame; Aki Nishihara; Yoko Takahashi; Kazuro Shiomi; Kazuhiko Otoguro; Satoshi Omura
Selective and potent in vitro antimalarial activities found in four microbial metabolites.
The Journal of antibiotics 2007;60(3):220-2.
2006: Hideaki Ui; Kazuro Shiomi; Hideaki Suzuki; Hiroko Hatano; Hiromi Morimoto; Yuichi Yamaguchi; Rokuro Masuma; Toshiaki Sunazuka; Hiroyuki Shimamura; Kimitoshi Sakamoto; Kiyoshi Kita; Hideto Miyoshi; Hiroshi Tomoda; Satoshi Omura
Verticipyrone, a new NADH-fumarate reductase inhibitor, produced by Verticillium sp. FKI-1083.
The Journal of antibiotics 2006;59(12):785-90.
2006: Souichi Monma; Toshiaki Sunazuka; Kenichiro Nagai; Takahiro Arai; Kazuro Shiomi; Ryosuke Matsui; Satoshi Omura
Verticilide: elucidation of absolute configuration and total synthesis.
Organic letters 2006;8(24):5601-4.
2006: Ryuji Uchida; Rie Imasato; Yuichi Yamaguchi; Rokuro Masuma; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Yaequinolones, new insecticidal antibiotics produced by Penicillium sp. FKI-2140. I. Taxonomy, fermentation, isolation and biological activity.
The Journal of antibiotics 2006;59(10):646-51.
2006: Hideaki Ui; Kazuro Shiomi; Hideaki Suzuki; Hiroko Hatano; Hiromi Morimoto; Yuichi Yamaguchi; Rokuro Masuma; Kimitoshi Sakamoto; Kiyoshi Kita; Hideto Miyoshi; Hiroshi Tomoda; Haruo Tanaka; Satoshi Omura
Paecilaminol, a new NADH-fumarate reductase inhibitor, produced by Paecilomyces sp. FKI-0550.
The Journal of antibiotics 2006;59(9):591-6.
2005: Ryuji Uchida; Rie Imasato; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Yaequinolones J1 and J2, novel insecticidal antibiotics from Penicillium sp. FKI-2140.
Organic letters 2005;7(25):5701-4.
2005: Ryuji Uchida; Rie Imasato; Yuichi Yamaguchi; Rokuro Masuma; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
New insecticidal antibiotics, hydroxyfungerins A and B, produced by Metarhizium sp. FKI-1079.
The Journal of antibiotics 2005;58(12):804-9.
2005: Ryuji Uchida; Rie Imasato; Yuichi Yamaguchi; Rokuro Masuma; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
New sesquicillins, insecticidal antibiotics produced by Albophoma sp. FKI-1778.
The Journal of antibiotics 2005;58(6):397-404.
2005: Kazuro Shiomi; Kenji Hatae; Hiroko Hatano; Atsuko Matsumoto; Yoko Takahashi; Cheng-Lin Jiang; Hiroshi Tomoda; Susumu Kobayashi; Haruo Tanaka; Satoshi Omura
A new antibiotic, antimycin Ag, produced by Streptomyces sp. K01-0031.
The Journal of antibiotics 2005;58(1):74-8.
2005: Kazuro Shiomi; Ryosuke Matsui; Miki Isozaki; Harumi Chiba; Takahiro Sugai; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Tomoko Chiba; Hua Yan; Yoshihiro Kitamura; Wataru Sugiura; Satoshi Omura; Haruo Tanaka
Fungal phenalenones inhibit HIV-1 integrase.
The Journal of antibiotics 2005;58(1):65-8.
2005: Kazuro Shiomi; Hideaki Ui; Hideaki Suzuki; Hiroko Hatano; Tohru Nagamitsu; Daisuke Takano; Hiroko Miyadera; Tetsuo Yamashita; Kiyoshi Kita; Hideto Miyoshi; Achim Harder; Hiroshi Tomoda; Satoshi Omura
A gamma-lactone form nafuredin, nafuredin-gamma, also inhibits helminth complex I.
The Journal of antibiotics 2005;58(1):50-5.
2005: Francesco V Rao; Douglas R Houston; Rolf G Boot; johannes aerts; Michael Hodkinson; David J Adams; Kazuro Shiomi; Satoshi Omura; Daan M F van Aalten
Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases.
Chemistry & biology 2005;12(1):65-76.
2004: Kenichiro Nagai; Kazuro Shiomi; Toshiaki Sunazuka; Achim Harder; Andreas Turberg; Satoshi Omura
Synthesis and biological evaluation of novel 4"-alkoxy avermectin derivatives.
Bioorganic & medicinal chemistry letters 2004;14(16):4135-9.
2003: Kenichiro Nagai; Toshiaki Sunazuka; Kazuro Shiomi; Achim Harder; Andreas Turberg; Satoshi Omura
Synthesis and biological activities of novel 4"-alkylidene avermectin derivatives.
Bioorganic & medicinal chemistry letters 2003;13(22):3943-6.
2003: Kazunobu Yamamoto; Hiroko Hatano; Masayoshi Arai; Kazuro Shiomi; Hiroshi Tomoda; Satoshi Omura
Structure elucidation of new monordens produced by Humicola sp. FO-2942.
The Journal of antibiotics 2003;56(6):533-8.
2003: Kazuhiko Otoguro; Hideaki Ui; Aki Ishiyama; Noriko Arai; Miyuki Kobayashi; Yoko Takahashi; Rokuro Masuma; Kazuro Shiomi; Haruki Yamada; Satoshi Omura
In vitro antimalarial activities of the microbial metabolites.
The Journal of antibiotics 2003;56(3):322-4.
2003: Hiroko Miyadera; Kazuro Shiomi; Hideaki Ui; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Hideto Miyoshi; Arihiro Osanai; Kiyoshi Kita; Satoshi Omura
Atpenins, potent and specific inhibitors of mitochondrial complex II (succinate-ubiquinone oxidoreductase).
Proceedings of the National Academy of Sciences of the United States of America 2003;100(2):473-7.
2002: Kazuro Shiomi; Kenji Hatae; Yuichi Yamaguchi; Rokuro Masuma; Hiroshi Tomoda; Susumu Kobayashi; Satoshi Omura
New antibiotics miyakamides produced by a fungus.
The Journal of antibiotics 2002;55(11):952-61.
2002: Douglas R Houston; Kazuro Shiomi; Noriko Arai; Satoshi Omura; Martin G Peter; Andreas Turberg; Bjørnar Synstad; Vincent G H Eijsink; Daan M F van Aalten
High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors: mimicry of carbohydrate substrate.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9127-32.
2001: Kazuhiko Otoguro; A Kohana; C Manabe; Aki Ishiyama; Hideaki Ui; Kazuro Shiomi; H Yamada; Satoshi Omura
Potent antimalarial activities of polyether antibiotic, X-206.
The Journal of antibiotics 2001;54(8):658-63.
2001: Daisuke Takano; Tohru Nagamitsu; Hideaki Ui; Kazuro Shiomi; Yuichi Yamaguchi; Rokuro Masuma; Isao Kuwajima; Satoshi Omura
Total synthesis of nafuredin, a selective NADH-fumarate reductase inhibitor.
Organic letters 2001;3(15):2289-91.
2001: Y Enomoto; Kazuro Shiomi; A Matsumoto; Y Takahashi; Yuzuru Iwai; Achim Harder; H Kölbl; H B Woodruff; Satoshi Omura
Isolation of a new antibiotic oligomycin G produced by Streptomyces sp. WK-6150.
The Journal of antibiotics 2001;54(3):308-13.
2001: Hideaki Ui; Kazuro Shiomi; Yuichi Yamaguchi; Rokuro Masuma; Tohru Nagamitsu; Daisuke Takano; Toshiaki Sunazuka; M Namikoshi; Satoshi Omura
Nafuredin, a novel inhibitor of NADH-fumarate reductase, produced by Aspergillus niger FT-0554.
The Journal of antibiotics 2001;54(3):234-8.
2001: Satoshi Omura; Hiroko Miyadera; Hideaki Ui; Kazuro Shiomi; Yuichi Yamaguchi; Rokuro Masuma; Tohru Nagamitsu; Daisuke Takano; Toshiaki Sunazuka; Achim Harder; H Kölbl; M Namikoshi; Hideto Miyoshi; Kensaku Sakamoto; Kiyoshi Kita
An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(1):60-2.
2000: N Arai; Kazuro Shiomi; Yuichi Yamaguchi; Rokuro Masuma; Yuzuru Iwai; A Turberg; H Kölbl; Satoshi Omura
Argadin, a new chitinase inhibitor, produced by Clonostachys sp. FO-7314.
Chemical & pharmaceutical bulletin 2000;48(10):1442-6.
2000: N Arai; Kazuro Shiomi; Yuzuru Iwai; Satoshi Omura
Argifin, a new chitinase inhibitor, produced by Gliocladium sp. FTD-0668. II. Isolation, physico-chemical properties, and structure elucidation.
The Journal of antibiotics 2000;53(6):609-14.
2000: Satoshi Omura; N Arai; Yuichi Yamaguchi; Rokuro Masuma; Yuzuru Iwai; M Namikoshi; A Turberg; H Kölbl; Kazuro Shiomi
Argifin, a new chitinase inhibitor, produced by Gliocladium sp. FTD-0668. I. Taxonomy, fermentation, and biological activities.
The Journal of antibiotics 2000;53(6):603-8.
2000: Kazuhiko Otoguro; Kazuro Shiomi; Yuichi Yamaguchi; N Arai; Toshiaki Sunazuka; Rokuro Masuma; Yuzuru Iwai; Satoshi Omura
Arisugacins C and D, novel acetylcholinesterase inhibitors and their related novel metabolites produced by Penicilium sp. FO-4259-11.
The Journal of antibiotics 2000;53(1):50-7.
1999: Junji Inokoshi; Kazuro Shiomi; Rokuro Masuma; Haruo Tanaka; H Yamada; Satoshi Omura
Funalenone, a novel collagenase inhibitor produced by Aspergillus niger.
The Journal of antibiotics 1999;52(12):1095-100.
1999: T Matsumoto; Aki Ishiyama; Yuichi Yamaguchi; Rokuro Masuma; Hideaki Ui; Kazuro Shiomi; H Yamada; Satoshi Omura
Novel cyclopentanone derivatives pentenocins A and B with interleukin-1beta converting enzyme inhibitory activity, produced by Trichoderma hamatum FO-6903.
The Journal of antibiotics 1999;52(8):754-7.
1999: Satoshi Omura; Y Enomoto; M Shinose; Y Takahashi; Yuzuru Iwai; Kazuro Shiomi
Isolation and structure of a new antibiotic viridomycin F produced by Streptomyces sp. K96-0188.
The Journal of antibiotics 1999;52(1):61-4.
1998: Y Tanaka; Kazuro Shiomi; K Kamei; M Sugoh-Hagino; Y Enomoto; F Fang; Yuichi Yamaguchi; Rokuro Masuma; C G Zhang; X W Zhang; Satoshi Omura
Antimalarial activity of radicicol, heptelidic acid and other fungal metabolites.
The Journal of antibiotics 1998;51(2):153-60.
1997: F Fang; Hideaki Ui; Kazuro Shiomi; Rokuro Masuma; Y Yamaguchi; C G Zhang; X W Zhang; Y Tanaka; Satoshi Omura
Two new components of the aspochalasins produced by Aspergillus sp.
The Journal of antibiotics 1997;50(11):919-25.
1997: N Arai; Kazuro Shiomi; S Takamatsu; K Komiyama; M Shinose; Y Takahashi; Y Tanaka; Y Iwai; J R Liu; Satoshi Omura
Amphistin, a new melanogenesis inhibitor, produced by an actinomycete.
The Journal of antibiotics 1997;50(10):808-14.
1997: Y Tanaka; H Yoshida; Y Enomoto; Kazuro Shiomi; M Shinose; Y Takahashi; J R Liu; Satoshi Omura
Malolactomycins C and D, new 40-membered macrolides active against Botrytis.
The Journal of antibiotics 1997;50(3):194-200.
1996: R Uchida; Kazuro Shiomi; Junji Inokoshi; Haruo Tanaka; Y Iwai; Satoshi Omura
Andrastin D, novel protein farnesyltransferase inhibitor produced by Penicillium sp. FO-3929.
The Journal of antibiotics 1996;49(12):1278-80.
1996: R Uchida; Kazuro Shiomi; Junji Inokoshi; Rokuro Masuma; T Kawakubo; H Tanaka; Y Iwai; Satoshi Omura
Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. I. Producing strain, fermentation, isolation, and biological activities.
The Journal of antibiotics 1996;49(9):932-4.
1996: R Uchida; Kazuro Shiomi; Toshiaki Sunazuka; Junji Inokoshi; A Nishizawa; T Hirose; Haruo Tanaka; Y Iwai; Satoshi Omura
Kurasoins A and B, new protein farnesyltransferase inhibitors produced by Paecilomyces sp. FO-3684. II. Structure elucidation and total synthesis.
The Journal of antibiotics 1996;49(9):886-9.
1996: F Kuno; Kazuro Shiomi; Kazuhiko Otoguro; Toshiaki Sunazuka; Satoshi Omura
Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. II. Structure elucidation.
The Journal of antibiotics 1996;49(8):748-51.
1996: F Kuno; Kazuhiko Otoguro; Kazuro Shiomi; Y Iwai; Satoshi Omura
Arisugacins A and B, novel and selective acetylcholinesterase inhibitors from Penicillium sp. FO-4259. I. Screening, taxonomy, fermentation, isolation and biological activity.
The Journal of antibiotics 1996;49(8):742-7.
1996: R Uchida; Kazuro Shiomi; Junji Inokoshi; Toshiaki Sunazuka; H Tanaka; Y Iwai; H Takayanagi; Satoshi Omura
Andrastins A-C, new protein farnesyltransferase inhibitors produced by Penicillium sp. FO-3929. II. Structure elucidation and biosynthesis.
The Journal of antibiotics 1996;49(5):418-24.
1996: Satoshi Omura; Junji Inokoshi; R Uchida; Kazuro Shiomi; Rokuro Masuma; T Kawakubo; Haruo Tanaka; Y Iwai; Seiji Kosemura; S Yamamura
Andrastins A-C, new protein farnesyltransferase inhibitors produced by Penicillium sp. FO-3929. I. Producing strain, fermentation, isolation, and biological activities.
The Journal of antibiotics 1996;49(5):414-7.
1996: Y Enomoto; Kazuro Shiomi; Masahiko Hayashi; Rokuro Masuma; T Kawakubo; K Tomosawa; Y Iwai; Satoshi Omura
Herquline B, a new platelet aggregation inhibitor produced by Penicillium herquei Fg-372.
The Journal of antibiotics 1996;49(1):50-3.
1995: Kazuro Shiomi; H Yang; Q Xu; N Arai; M Namiki; Masahiko Hayashi; Junji Inokoshi; H Takeshima; Rokuro Masuma; Kanki Komiyama
Phenopyrrozin, a new radical scavenger produced by Penicillium sp. FO-2047.
The Journal of antibiotics 1995;48(12):1413-8.
1995: Satoshi Omura; F Kuno; Kazuhiko Otoguro; Toshiaki Sunazuka; Kazuro Shiomi; R Masuma; Y Iwai
Arisugacin, a novel and selective inhibitor of acetylcholinesterase from Penicillium sp. FO-4259.
The Journal of antibiotics 1995;48(7):745-6.
1995: Kazuro Shiomi; N Arai; M Shinose; Y Takahashi; H Yoshida; J Iwabuchi; Y Tanaka; Satoshi Omura
New antibiotics phthoxazolins B, C and D produced by Streptomyces sp. KO-7888.
The Journal of antibiotics 1995;48(7):714-9.
1995: N Arai; Kazuro Shiomi; Hiroshi Tomoda; Noriko Tabata; D J Yang; Rokuro Masuma; T Kawakubo; Satoshi Omura
Isochromophilones III-VI, inhibitors of acyl-CoA:cholesterol acyltransferase produced by Penicillium multicolor FO-3216.
The Journal of antibiotics 1995;48(7):696-702.
1995: H Yamada; Kazuro Shiomi; Q Xu; T Nagai; M Shibata; I Oya; Y Takahashi; Satoshi Omura
New glycosidases inhibitors, panosialins D and wD produced by Streptomyces sp. OH-5186.
The Journal of antibiotics 1995;48(3):205-10.
1995: X H Huang; H Nishida; Hiroshi Tomoda; Noriko Tabata; Kazuro Shiomi; D J Yang; H Takayanagi; Satoshi Omura
Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. II. Structure elucidation of terpendoles A, B, C and D.
The Journal of antibiotics 1995;48(1):5-11.
1994: H Yoshida; N Arai; M Sugoh; J Iwabuchi; Kazuro Shiomi; M Shinose; Y Tanaka; Satoshi Omura
4-chlorothreonine, a herbicidal antimetabolite produced by Streptomyces sp. OH-5093.
The Journal of antibiotics 1994;47(10):1165-6.
1994: Kazuro Shiomi; K Haneda; Hiroshi Tomoda; Y Iwai; Satoshi Omura
Cytosaminomycins, new anticoccidial agents produced by Streptomyces sp. KO-8119. II. Structure elucidation of cytosaminomycins A, B, C and D.
The Journal of antibiotics 1994;47(7):782-6.
1993: Kanki Komiyama; Kazuhiko Otoguro; T Segawa; Kazuro Shiomi; H Yang; Y Takahashi; Masahiko Hayashi; T Otani; Satoshi Omura
A new antibiotic, cypemycin. Taxonomy, fermentation, isolation and biological characteristics.
The Journal of antibiotics 1993;46(11):1666-71.
1993: Y Tanaka; I Kanaya; Kazuro Shiomi; H Tanaka; Satoshi Omura
Phthoxazolin A, a specific inhibitor of cellulose biosynthesis from microbial origin. II. Isolation, physico-chemical properties, and structural elucidation.
The Journal of antibiotics 1993;46(8):1214-8.
1993: Kazuro Shiomi; H Yang; Junji Inokoshi; D Van der Pyl; A Nakagawa; H Takeshima; Satoshi Omura
Pepticinnamins, new farnesyl-protein transferase inhibitors produced by an actinomycete. II. Structural elucidation of pepticinnamin E.
The Journal of antibiotics 1993;46(2):229-34.
1992: D Van der Pyl; Junji Inokoshi; Kazuro Shiomi; H Yang; H Takeshima; Satoshi Omura
Inhibition of farnesyl-protein transferase by gliotoxin and acetylgliotoxin.
The Journal of antibiotics 1992;45(11):1802-5.