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Kanemitsu Shirasuna

Research Profile

Disorders

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Immunohistochemistry

Chemicals & Drugs

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J-N Hayashida; Eui Kawamura; Wataru Kumamaru; M Moriyama; Shotaro Nakamura; Yukiko Ohyama; Masafumi Sasaki; Takeshi Toyoshima; Kanemitsu Shirasuna
Possible involvement of cytokines, chemokines and chemokine receptors in the initiation and progression of chronic GVHD.
Satomi Chigita; Yosuke Kobayashi; Megumi Onoda; Miyuki Shimoda; Masakazu Abe; Tsuyoshi Sugiura; Kanemitsu Shirasuna
CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cells.
Miyuki Shimoda; Tsuyoshi Sugiura; Satomi Chigita; Ikumi Imajyo; Kotaro Ishii; Yousuke Kobayashi; Katsuhiro Seki; Kanemitsu Shirasuna
The T-box transcription factor Brachyury regulates epithelial-mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells.

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All Publications

2013: J-N Hayashida; Eui Kawamura; Wataru Kumamaru; M Moriyama; Shotaro Nakamura; Yukiko Ohyama; Masafumi Sasaki; Takeshi Toyoshima; Kanemitsu Shirasuna
Possible involvement of cytokines, chemokines and chemokine receptors in the initiation and progression of chronic GVHD.
Bone marrow transplantation 2013;48(1):115-23.
2012: Satomi Chigita; Yosuke Kobayashi; Megumi Onoda; Miyuki Shimoda; Masakazu Abe; Tsuyoshi Sugiura; Kanemitsu Shirasuna
CD82 inhibits canonical Wnt signalling by controlling the cellular distribution of β-catenin in carcinoma cells.
International journal of oncology 2012;41(6):2021-8.
2012: Miyuki Shimoda; Tsuyoshi Sugiura; Satomi Chigita; Ikumi Imajyo; Kotaro Ishii; Yousuke Kobayashi; Katsuhiro Seki; Kanemitsu Shirasuna
The T-box transcription factor Brachyury regulates epithelial-mesenchymal transition in association with cancer stem-like cells in adenoid cystic carcinoma cells.
BMC cancer 2012;12():377.
2012: Yuta Yanai; Naoya Yoshihama; Kanemitsu Shirasuna; Tsuyoshi Sugiura; Y Takenoshita; Naonari Akimoto; Takahiro Fujinaga; Kohei Hayashi; Ikumi Imajyo; Yosuke Kobayashi; Yoshihide Mori
Retrospective Study of Selective Submandibular Neck Dissection versus Radical Neck Dissection for N0 or N1 Necks in Level I Patients with Oral Squamous Cell Carcinoma.
Journal of oncology 2012;2012():634183.
2011: Kotaro Ishii; Miyuki Shimoda; Tsuyoshi Sugiura; Katsuhiro Seki; Miho Takahashi; Masakazu Abe; Ryosuke Matsuki; Yoshiko Inoue; Kanemitsu Shirasuna
Involvement of epithelial-mesenchymal transition in adenoid cystic carcinoma metastasis.
International journal of oncology 2011;38(4):921-31.
2009: Masaki Matsuura; Mitsuho Onimaru; Yoshikazu Yonemitsu; Hanako Suzuki; Toshiaki Nakano; Hiroaki Ishibashi; Kanemitsu Shirasuna; Katsuo Sueishi
Autocrine loop between vascular endothelial growth factor (VEGF)-C and VEGF receptor-3 positively regulates tumor-associated lymphangiogenesis in oral squamoid cancer cells.
The American journal of pathology 2009;175(4):1709-21.
2009: Yoshie Yahara; Yasutaka Kubota; T Yamashiro; Kanemitsu Shirasuna
Eruption prediction of mandibular premolars associated with dentigerous cysts.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2009;108(1):28-31.
2009: Seiko Tabuchi; Tetsuya Sakuta; Tohru Oyama; Masayuki Tokuda; Syouko Tatsuyama; Takeshi Kajihara; Shigetaka Nagaoka; Mahiro Beppu; Kazumasa Sugihara; Tetsuro Ikebe; Kanemitsu Shirasuna; Mitsuo Torii
Runt-related gene 2 is involved in the inhibition of matrix metalloproteinase-13 expression by roxithromycin in human gingival epithelial cell cultures.
Journal of periodontal research 2009;44(3):283-8.
2009: Y Suyama; Yasutaka Kubota; T Yamashiro; Tomohiro Ninomiya; Takehiko Koji; Kanemitsu Shirasuna
Expression of keratinocyte growth factor and its receptor in odontogenic keratocysts.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2009;38(5):476-80.
2009: Tsuyoshi Sugiura; Yoshiko Inoue; Ryosuke Matsuki; Kotaro Ishii; Miho Takahashi; Masakazu Abe; Kanemitsu Shirasuna
VEGF-C and VEGF-D expression is correlated with lymphatic vessel density and lymph node metastasis in oral squamous cell carcinoma: Implications for use as a prognostic marker.
International journal of oncology 2009;34(3):673-80.
2008: Yoko Suyama; Yasutaka Kubota; Tomohiro Ninomiya; Kanemitsu Shirasuna
Immunohistochemical analysis of interleukin-1 alpha, its type I receptor and antagonist in keratocystic odontogenic tumors.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2008;37(9):560-4.
2008: Masakazu Abe; Tsuyoshi Sugiura; Miho Takahashi; Kotaro Ishii; Miyuki Shimoda; Kanemitsu Shirasuna
A novel function of CD82/KAI-1 on E-cadherin-mediated homophilic cellular adhesion of cancer cells.
Cancer letters 2008;266(2):163-70.
2008: Samah Abu-Ali; Abbas Fotovati; Kanemitsu Shirasuna
Tyrosine-kinase inhibition results in EGFR clustering at focal adhesions and consequent exocytosis in uPAR down-regulated cells of head and neck cancers.
Molecular cancer 2008;7():47.
2007: Miho Takahashi; Tsuyoshi Sugiura; Masakazu Abe; Koutaro Ishii; Kanemitsu Shirasuna
Regulation of c-Met signaling by the tetraspanin KAI-1/CD82 affects cancer cell migration.
International journal of cancer. Journal international du cancer 2007;121(9):1919-29.
2007: Yongtao Yu; Alexander S Baras; Kanemitsu Shirasuna; Henry F Frierson; Christopher A Moskaluk
Concurrent loss of heterozygosity and copy number analysis in adenoid cystic carcinoma by SNP genotyping arrays.
Laboratory investigation; a journal of technical methods and pathology 2007;87(5):430-9.
2007: S Ogata; Yasutaka Kubota; T Yamashiro; H Takeuchi; Tomohiro Ninomiya; Y Suyama; Kanemitsu Shirasuna
Signaling pathways regulating IL-1alpha-induced COX-2 expression.
Journal of dental research 2007;86(2):186-91.
2006: Sachie Ogata; Yasutaka Kubota; Shinji Satoh; Shinich Ito; Hiroshi Takeuchi; Megumi Ashizuka; Kanemitsu Shirasuna
Ca2+ stimulates COX-2 expression through calcium-sensing receptor in fibroblasts.
Biochemical and biophysical research communications 2006;351(4):808-14.
2006: Takeshi Toyoshima; Shotaro Nakamura; Wataru Kumamaru; Eui Kawamura; H Ishibashi; J-N Hayashida; M Moriyama; Yukiko Ohyama; Masafumi Sasaki; Kanemitsu Shirasuna
Expression of tumor-associated antigen RCAS1 and its possible involvement in immune evasion in oral squamous cell carcinoma.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2006;35(6):361-8.
2005: Yasutaka Kubota; Kanemitsu Shirasuna
The use of free-periosteum for secondary bone grafting to the maxillary alveolar clefts.
Annals of plastic surgery 2005;55(6):599-602.
2005: Jun Mori; Fumi Takahashi-Yanaga; Yoshikazu Miwa; Yutaka Watanabe; Masato Hirata; Sachio Morimoto; Kanemitsu Shirasuna; Toshiyuki Sasaguri
Differentiation-inducing factor-1 induces cyclin D1 degradation through the phosphorylation of Thr286 in squamous cell carcinoma.
Experimental cell research 2005;310(2):426-33.
2005: S Oka; Yasutaka Kubota; T Yamashiro; S Ogata; Tomohiro Ninomiya; S Ito; Kanemitsu Shirasuna
Effects of positive pressure in odontogenic keratocysts.
Journal of dental research 2005;84(10):913-8.
2005: T Ikebe; K Seki; Shotaro Nakamura; Y Takenoshita; H Nakayama; Masanori Shinohara; Kanemitsu Shirasuna
Severity of oral mucositis correlates with the response of oral cancer to preoperative radiochemotherapy.
International journal of oral and maxillofacial surgery 2005;34(6):642-5.
2005: Hideki Nakayama; Tetsuro Ikebe; Kanemitsu Shirasuna
Effects of IkappaB kinase alpha on the differentiation of squamous carcinoma cells.
Oral oncology 2005;41(7):729-37.
2005: Samah Abu-Ali; Tsuyoshi Sugiura; Miho Takahashi; Toru Shiratsuchi; Tatsuya Ikari; Katsuhiro Seki; Akimitsu Hiraki; Ryousuke Matsuki; Kanemitsu Shirasuna
Expression of the urokinase receptor regulates focal adhesion assembly and cell migration in adenoid cystic carcinoma cells.
Journal of cellular physiology 2005;203(2):410-9.
2004: Tetsuro Ikebe; Hideki Nakayama; Masanori Shinohara; Kanemitsu Shirasuna
NF-kappaB involvement in tumor-stroma interaction of squamous cell carcinoma.
Oral oncology 2004;40(10):1048-56.
2004: Yasutaka Kubota; T Yamashiro; S Oka; Tomohiro Ninomiya; S Ogata; Kanemitsu Shirasuna
Relation between size of odontogenic jaw cysts and the pressure of fluid within.
The British journal of oral & maxillofacial surgery 2004;42(5):391-5.
2004: Wataru Kumamaru; Seiji Nakamura; Tsutomu Kadena; Akira Yamada; Eui Kawamura; Masanori Sasaki; Yukiko Ohyama; Takeshi Toyoshima; Jun-Nosuke Hayashida; Kyogo Itoh; Kanemitsu Shirasuna
T-cell receptor Vbeta gene usage by T cells reactive with the tumor-rejection antigen SART-1 in oral squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2004;108(5):686-95.
2003: Eiji Nakayama; Kazunori Yoshiura; Satoru Ozeki; Hideki Nakayama; Toshihiro Yamaguchi; Hiromasa Yoshikawa; Shigenobu Kanda; Masamichi Ohishi; Kanemitsu Shirasuna
The correlation of histologic features with a panoramic radiography pattern and a computed tomography pattern of bone destruction in carcinoma of the mandibular gingiva.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2003;96(6):774-82.
2003: Tatsuya Ikari; Akimitsu Hiraki; Katsuhiro Seki; Tsuyoshi Sugiura; Kunio Matsumoto; Kanemitsu Shirasuna
Involvement of hepatocyte growth factor in branching morphogenesis of murine salivary gland.
Developmental dynamics : an official publication of the American Association of Anatomists 2003;228(2):173-84.
2003: Eui Kawamura; Shotaro Nakamura; Masafumi Sasaki; Yukiko Ohyama; Tsutomu Kadena; Wataru Kumamaru; Kanemitsu Shirasuna
Accumulation of oligoclonal T cells in the infiltrating lymphocytes in oral lichen planus.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2003;32(5):282-9.
2002: Toru Shiratsuchi; Hiroaki Ishibashi; Kanemitsu Shirasuna
Inhibition of epidermal growth factor-induced invasion by dexamethasone and AP-1 decoy in human squamous cell carcinoma cell lines.
Journal of cellular physiology 2002;193(3):340-8.
2002: Mitsuho Onimaru; Yoshikazu Yonemitsu; Mitsugu Tanii; Kazunori Nakagawa; Ichiro Masaki; Shinji Okano; Hiroaki Ishibashi; Kanemitsu Shirasuna; Mamoru Hasegawa; Katsuo Sueishi
Fibroblast growth factor-2 gene transfer can stimulate hepatocyte growth factor expression irrespective of hypoxia-mediated downregulation in ischemic limbs.
Circulation research 2002;91(10):923-30.
2002: Tomohiro Ninomiya; Yasutaka Kubota; Takehiko Koji; Kanemitsu Shirasuna
Marsupialization inhibits interleukin-1alpha expression and epithelial cell proliferation in odontogenic keratocysts.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2002;31(9):526-33.
2002: Akimitsu Hiraki; Kanemitsu Shirasuna; Tatsuya Ikari; Masanori Shinohara; David R Garrod
Calcium induces differentiation of primary human salivary acinar cells.
Journal of cellular physiology 2002;193(1):55-63.
2002: Shohko Tsunawaki; Seiji Nakamura; Yukiko Ohyama; Masanori Sasaki; Akiko Ikebe-Hiroki; Akimitsu Hiraki; Tsutomu Kadena; Eui Kawamura; Wataru Kumamaru; Masanori Shinohara; Kanemitsu Shirasuna
Possible function of salivary gland epithelial cells as nonprofessional antigen-presenting cells in the development of Sjögren's syndrome.
The Journal of rheumatology 2002;29(9):1884-96.
2002: Megumi Ashizuka; Takao Fukuda; Takanori Nakamura; Kanemitsu Shirasuna; Kazuhiro Iwai; Hiroto Izumi; Kimitoshi Kohno; Michihiko Kuwano; Takeshi Uchiumi
Novel translational control through an iron-responsive element by interaction of multifunctional protein YB-1 and IRP2.
Molecular and cellular biology 2002;22(18):6375-83.
2002: Satoshi Kaneko; Takesumi Yoshimura; Kunio Ikemura; Kanemitsu Shirasuna; Jingo Kusukawa; Masamichi Ohishi; Ryosuke Shiba; Hajime Sunakawa; Kazuhiro Tominaga; Kazumasa Sugihara; Masanori Shinohara; Takeshi Katsuki; Shigetaka Yanagisawa; Hideo Kurokawa; Tamotsu Mimura; Hisazumi Ikeda; Shigeru Yamabe; Satoru Ozeki
Primary neck management among patients with cancer of the oral cavity without clinical nodal metastases: A decision and sensitivity analysis.
Head & neck 2002;24(6):582-90.
2002: Mahiro Beppu; Tetsuro Ikebe; Kanemitsu Shirasuna
The inhibitory effects of immunosuppressive factors, dexamethasone and interleukin-4, on NF-kappaB-mediated protease production by oral cancer.
Biochimica et biophysica acta 2002;1586(1):11-22.
2002: Yasutaka Kubota; S Oka; S Nakagawa; Kanemitsu Shirasuna
Interleukin-1alpha enhances type I collagen-induced activation of matrix metalloproteinase-2 in odontogenic keratocyst fibroblasts.
Journal of dental research 2002;81(1):23-7.
2001: Hideki Nakayama; Tetsuro Ikebe; M Beppu; Kanemitsu Shirasuna
High expression levels of nuclear factor kappaB, IkappaB kinase alpha and Akt kinase in squamous cell carcinoma of the oral cavity.
Cancer 2001;92(12):3037-44.
2001: Yasutaka Kubota; S Nitta; S Oka; S Nakagawa; Tomohiro Ninomiya; Kanemitsu Shirasuna
Discrimination of ameloblastomas from odontogenic keratocysts by cytokine levels and gelatinase species of the intracystic fluids.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2001;30(7):421-7.
2001: Hiroaki Ishibashi; T Shiratuchi; Kazunori Nakagawa; Mitsuho Onimaru; Tsuyoshi Sugiura; Katsuo Sueishi; Kanemitsu Shirasuna
Hypoxia-induced angiogenesis of cultured human salivary gland carcinoma cells enhances vascular endothelial growth factor production and basic fibroblast growth factor release.
Oral oncology 2001;37(1):77-83.
2000: Hiroaki Ishibashi; Kazunori Nakagawa; Mitsuho Onimaru; E J Castellanous; Yasufumi Kaneda; Yutaka Nakashima; Kanemitsu Shirasuna; Katsuo Sueishi
Sp1 decoy transfected to carcinoma cells suppresses the expression of vascular endothelial growth factor, transforming growth factor beta1, and tissue factor and also cell growth and invasion activities.
Cancer research 2000;60(22):6531-6.
2000: C Y Li; Kanemitsu Shirasuna; H Ishibashi; Hideki Nakayama; Tamotsu Kiyoshima
Epithelial-myoepithelial carcinoma arising in pleomorphic adenoma of the palate.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2000;90(4):460-5.
2000: Toru Chikui; Kenji Yuasa; Masafumi Inagaki; Masamichi Ohishi; Kanemitsu Shirasuna; Shigenobu Kanda
Tumor recurrence criteria for postoperative contrast-enhanced computed tomography after surgical treatment of oral cancer and flap repair.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2000;90(3):369-76.
2000: Yasutaka Kubota; Tomohiro Ninomiya; S Oka; Y Takenoshita; Kanemitsu Shirasuna
Interleukin-1alpha-dependent regulation of matrix metalloproteinase-9(MMP-9) secretion and activation in the epithelial cells of odontogenic jaw cysts.
Journal of dental research 2000;79(6):1423-30.
2000: Masafumi Sasaki; Shotaro Nakamura; Yukiko Ohyama; Masanori Shinohara; I Ezaki; Hiromitsu Hara; Tsutomu Kadena; Kenji Kishihara; Kenji Yamamoto; Kikuo Nomoto; Kanemitsu Shirasuna
Accumulation of common T cell clonotypes in the salivary glands of patients with human T lymphotropic virus type I-associated and idiopathic Sjögren's syndrome.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(5):2823-31.
2000: Tetsuro Ikebe; E Jimi; M Beppu; Hiroshi Takeuchi; H Nakayama; Kanemitsu Shirasuna
Aging-dependent proteolysis of NF-kappaB in human fibroblasts.
Journal of cellular physiology 2000;182(2):247-55.
1999: Yasutaka Kubota; Y Takenoshita; K Takamori; M Kanamoto; Kanemitsu Shirasuna
Levandoski panographic analysis in the diagnosis of hyperplasia of the coronoid process.
The British journal of oral & maxillofacial surgery 1999;37(5):409-11.
1999: S Kurahara; Masanori Shinohara; T Ikebe; Seiji Nakamura; M Beppu; Akimitsu Hiraki; H Takeuchi; Kanemitsu Shirasuna
Expression of MMPS, MT-MMP, and TIMPs in squamous cell carcinoma of the oral cavity: correlations with tumor invasion and metastasis.
Head & neck 1999;21(7):627-38.
1999: S Kurahara; Masanori Shinohara; T Ikebe; Seiji Nakamura; Akimitsu Hiraki; M Sasaki; M Beppu; Kanemitsu Shirasuna
Immunohistochemical study of sialyl Le(a) and sialyl Le(x) antigen in oral squamous cell carcinoma: the association of sialyl Le(a) expression with the metastatic potential.
Head & neck 1999;21(4):330-7.
1999: T Ikebe; Masanori Shinohara; H Takeuchi; M Beppu; S Kurahara; Seiji Nakamura; Kanemitsu Shirasuna
Gelatinolytic activity of matrix metalloproteinase in tumor tissues correlates with the invasiveness of oral cancer.
Clinical & experimental metastasis 1999;17(4):315-23.
1999: Masanori Shinohara; Seiji Nakamura; M Sasaki; S Kurahara; T Ikebe; T Harada; Kanemitsu Shirasuna
Expression of integrins in squamous cell carcinoma of the oral cavity. Correlations with tumor invasion and metastasis.
American journal of clinical pathology 1999;111(1):75-88.
1998: Yukiko Ohyama; Shotaro Nakamura; Hiromitsu Hara; Masanori Shinohara; Masafumi Sasaki; Akiko Ikebe-Hiroki; Tsuyoshi Mouri; Shohko Tsunawaki; K Abe; Kanemitsu Shirasuna; Kikuo Nomoto
Accumulation of human T lymphotropic virus type I-infected T cells in the salivary glands of patients with human T lymphotropic virus type I-associated Sjögren's syndrome.
Arthritis and rheumatism 1998;41(11):1972-8.
1998: T Ikebe; H Takeuchi; E Jimi; M Beppu; Masanori Shinohara; Kanemitsu Shirasuna
Involvement of proteasomes in migration and matrix metalloproteinase-9 production of oral squamous cell carcinoma.
International journal of cancer. Journal international du cancer 1998;77(4):578-85.
1998: Masanori Shinohara; Akimitsu Hiraki; T Ikebe; Seiji Nakamura; S Kurahara; Kanemitsu Shirasuna; D R Garrod
Immunohistochemical study of desmosomes in oral squamous cell carcinoma: correlation with cytokeratin and E-cadherin staining, and with tumour behaviour.
The Journal of pathology 1998;184(4):369-81.
1997: Shotaro Nakamura; Akiko Ikebe-Hiroki; Masanori Shinohara; Yukiko Ohyama; Tsuyoshi Mouri; Masafumi Sasaki; Kanemitsu Shirasuna; Kikuo Nomoto
An association between salivary gland disease and serological abnormalities in Sjögren's syndrome.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 1997;26(9):426-30.
1997: Kanemitsu Shirasuna
[Idiopathic salivary gland tumors].
Fukuoka igaku zasshi = Hukuoka acta medica 1997;88(8):289-93.
1997: A Hiraki; Shotaro Nakamura; K Abe; Y Takenoshita; Y Horinouchi; Masanori Shinohara; Kanemitsu Shirasuna
Numb chin syndrome as an initial symptom of acute lymphocytic leukemia: report of three cases.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 1997;83(5):555-61.
1996: S Nakamura; A Hiroki; Masanori Shinohara; H Gondo; Yukiko Ohyama; Tsuyoshi Mouri; M Sasaki; Kanemitsu Shirasuna; M Harada; Y Niho
Oral involvement in chronic graft-versus-host disease after allogeneic bone marrow transplantation.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 1996;82(5):556-63.
1996: Tsuyoshi Mouri; S Nakamura; Yukiko Ohyama; Goro Matsuzaki; Masanori Shinohara; K Kishihara; A Hiroki; M Oka; Kanemitsu Shirasuna; Kikuo Nomoto
T cell receptor V alpha and V beta gene usage by tumour-infiltrating lymphocytes in oral squamous cell carcinoma.
Cancer immunology, immunotherapy : CII 1996;43(1):10-8.