Username

Password

Forgot Password?

Preview

Sign-in free and Explore the Exciting World of BiomedExperts:

Over 1.500.000 Profiles
More than 1.800 Organizations worldwide
State of the Art Network Visualizations

Manage your own Profile
Locate Experts in your Country/Region
Locate Experts in your 1. and 2. Level Network
Connect to Experts Worldwide

NetworkView

Assia Shisheva

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Living Beings

Anatomy

Phenomena

Phosphorylation

Physiology

Protein Transport

Sign-in to see full Profile

Network (preview)

Co-Publications
Name
38
Ikonomov, Ognian
26
Sbrissa, Diego
12
Shechter, Yoram
10
Stoynev, AG
5
Mlak, Krzysztof
4
Deeb, Robert
3
Czech, Michael
3
Ijuin, Takeshi
3
Dondapati, Rajeswari
3
Takenawa, Tadaomi
3
Chinni, Sreenivasa
2
DeMarco, Carmen
2
Buxton, JM
1
Cooke, Frank
1
Bailey, Charles

Sign-in to see all Coauthors

Publications

TOP 3
Ikonomov Ognian C; Sbrissa Diego; Ijuin Takeshi; Takenawa Tadaomi; Shisheva Assia
Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes.
Ikonomov Ognian C; Sbrissa Diego; Shisheva Assia
YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes.
Ikonomov Ognian C; Fligger Jason; Sbrissa Diego; Dondapati Rajeswari; Mlak Krzysztof; Deeb Robert; Shisheva Assia
Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.

Sign-in to see all Publications

Sign in free and see...

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the visualized research activity
of experts around the globe

Sign-in to see more

Geonetwork of Assia Shisheva (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

Sign-in to see more

All Publications

2009: Ikonomov Ognian C; Sbrissa Diego; Ijuin Takeshi; Takenawa Tadaomi; Shisheva Assia
Sac3 is an insulin-regulated phosphatidylinositol 3,5-bisphosphate phosphatase: gain in insulin responsiveness through Sac3 down-regulation in adipocytes.
The Journal of biological chemistry 2009;284(36):23961-71.
2009: Ikonomov Ognian C; Sbrissa Diego; Shisheva Assia
YM201636, an inhibitor of retroviral budding and PIKfyve-catalyzed PtdIns(3,5)P2 synthesis, halts glucose entry by insulin in adipocytes.
Biochemical and biophysical research communications 2009;382(3):566-70.
2009: Ikonomov Ognian C; Fligger Jason; Sbrissa Diego; Dondapati Rajeswari; Mlak Krzysztof; Deeb Robert; Shisheva Assia
Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
The Journal of biological chemistry 2009;284(6):3750-61.
2008: Sbrissa Diego; Ikonomov Ognian C; Fenner Homer; Shisheva Assia
ArPIKfyve homomeric and heteromeric interactions scaffold PIKfyve and Sac3 in a complex to promote PIKfyve activity and functionality.
Journal of molecular biology 2008;384(4):766-79.
2008: Shisheva Assia
Phosphoinositides in insulin action on GLUT4 dynamics: not just PtdIns(3,4,5)P3.
American journal of physiology. Endocrinology and metabolism 2008;295(3):E536-44.
2008: Shisheva Assia
PIKfyve: Partners, significance, debates and paradoxes.
Cell biology international 2008;32(6):591-604.
2007: Kim Jayoung; Jahng Wan Jin; Di Vizio Dolores; Lee Julie S; Jhaveri Raj; Rubin Mark A; Shisheva Assia; Freeman Michael R
The phosphoinositide kinase PIKfyve mediates epidermal growth factor receptor trafficking to the nucleus.
Cancer research 2007;67(19):9229-37.
2007: Sbrissa Diego; Ikonomov Ognian C; Fu Zhiyao; Ijuin Takeshi; Gruenberg Jean; Takenawa Tadaomi; Shisheva Assia
Core protein machinery for mammalian phosphatidylinositol 3,5-bisphosphate synthesis and turnover that regulates the progression of endosomal transport. Novel Sac phosphatase joins the ArPIKfyve-PIKfyve complex.
The Journal of biological chemistry 2007;282(33):23878-91.
2007: Ikonomov Ognian C; Sbrissa Diego; Dondapati Rajeswari; Shisheva Assia
ArPIKfyve-PIKfyve interaction and role in insulin-regulated GLUT4 translocation and glucose transport in 3T3-L1 adipocytes.
Experimental cell research 2007;313(11):2404-16.
2006: Kong Anne M; Horan Kristy A; Sriratana Absorn; Bailey Charles G; Collyer Luke J; Nandurkar Harshal H; Shisheva Assia; Layton Meredith J; Rasko John E J; Rowe Tony; Mitchell Christina A
Phosphatidylinositol 3-phosphate [PtdIns3P] is generated at the plasma membrane by an inositol polyphosphate 5-phosphatase: endogenous PtdIns3P can promote GLUT4 translocation to the plasma membrane.
Molecular and cellular biology 2006;26(16):6065-81.
2006: Ikonomov Ognian C; Sbrissa Diego; Shisheva Assia
Localized PtdIns 3,5-P2 synthesis to regulate early endosome dynamics and fusion.
American journal of physiology. Cell physiology 2006;291(2):C393-404.
2006: Xu Yong; Lee Stephanie A; Kutateladze Tatiana G; Sbrissa Diego; Shisheva Assia; Prestwich Glenn D
Chemical synthesis and molecular recognition of phosphatase-resistant analogues of phosphatidylinositol-3-phosphate.
Journal of the American Chemical Society 2006;128(3):885-97.
2005: Sbrissa Diego; Shisheva Assia
Acquisition of unprecedented phosphatidylinositol 3,5-bisphosphate rise in hyperosmotically stressed 3T3-L1 adipocytes, mediated by ArPIKfyve-PIKfyve pathway.
The Journal of biological chemistry 2005;280(9):7883-9.
2005: Sbrissa Diego; Ikonomov Ognian C; Shisheva Assia
Analysis of potential binding of the recombinant Rab9 effector p40 to phosphoinositide-enriched synthetic liposomes.
Methods in enzymology 2005;403():696-705.
2004: Sbrissa Diego; Ikonomov Ognian C; Strakova Jana; Dondapati Rajeswari; Mlak Krzysztof; Deeb Robert; Silver Robert; Shisheva Assia
A mammalian ortholog of Saccharomyces cerevisiae Vac14 that associates with and up-regulates PIKfyve phosphoinositide 5-kinase activity.
Molecular and cellular biology 2004;24(23):10437-47.
2004: Sbrissa Diego; Ikonomov Ognian C; Strakova Jana; Shisheva Assia
Role for a novel signaling intermediate, phosphatidylinositol 5-phosphate, in insulin-regulated F-actin stress fiber breakdown and GLUT4 translocation.
Endocrinology 2004;145(11):4853-65.
2004: Tsujita Kazuya; Itoh Toshiki; Ijuin Takeshi; Yamamoto Akitsugu; Shisheva Assia; Laporte Jocelyn; Takenawa Tadaomi
Myotubularin regulates the function of the late endosome through the gram domain-phosphatidylinositol 3,5-bisphosphate interaction.
The Journal of biological chemistry 2004;279(14):13817-24.
2003: Ikonomov Ognian C; Sbrissa Diego; Mlak Krzysztof; Deeb Robert; Fligger Jason; Soans Aleric; Finley Russell L; Shisheva Assia
Active PIKfyve associates with and promotes the membrane attachment of the late endosome-to-trans-Golgi network transport factor Rab9 effector p40.
The Journal of biological chemistry 2003;278(51):50863-71.
2003: Ikonomov Ognian C; Sbrissa Diego; Foti Michelangelo; Carpentier Jean-Louis; Shisheva Assia
PIKfyve controls fluid phase endocytosis but not recycling/degradation of endocytosed receptors or sorting of procathepsin D by regulating multivesicular body morphogenesis.
Molecular biology of the cell 2003;14(11):4581-91.
2003: Shisheva Assia
Regulating Glut4 vesicle dynamics by phosphoinositide kinases and phosphoinositide phosphatases.
Frontiers in bioscience : a journal and virtual library 2003;8():s945-6.
2002: Ikonomov Ognian C; Sbrissa Diego; Mlak Krzysztof; Shisheva Assia
Requirement for PIKfyve enzymatic activity in acute and long-term insulin cellular effects.
Endocrinology 2002;143(12):4742-54.
2002: Sbrissa Diego; Ikonomov Ognian C; Deeb Robert; Shisheva Assia
Phosphatidylinositol 5-phosphate biosynthesis is linked to PIKfyve and is involved in osmotic response pathway in mammalian cells.
The Journal of biological chemistry 2002;277(49):47276-84.
2002: Ikonomov Ognian C; Sbrissa Diego; Yoshimori Tamotsu; Cover Timothy L; Shisheva Assia
PIKfyve Kinase and SKD1 AAA ATPase define distinct endocytic compartments. Only PIKfyve expression inhibits the cell-vacoulating activity of Helicobacter pylori VacA toxin.
The Journal of biological chemistry 2002;277(48):46785-90.
2002: Ikonomov Ognian C; Sbrissa Diego; Mlak Kristopher; Kanzaki Makoto; Pessin Jeffrey; Shisheva Assia
Functional dissection of lipid and protein kinase signals of PIKfyve reveals the role of PtdIns 3,5-P2 production for endomembrane integrity.
The Journal of biological chemistry 2002;277(11):9206-11.
2002: Sbrissa Diego; Ikonomov Ognian C; Shisheva Assia
Phosphatidylinositol 3-phosphate-interacting domains in PIKfyve. Binding specificity and role in PIKfyve. Endomenbrane localization.
The Journal of biological chemistry 2002;277(8):6073-9.
2001: Grunberger G; Qiang X; Li Z; Mathews S T; Sbrissa D; Shisheva A; Sima A A
Molecular basis for the insulinomimetic effects of C-peptide.
Diabetologia 2001;44(10):1247-57.
2001: Sbrissa D; Ikonomov O; Shisheva A
Selective insulin-induced activation of class I(A) phosphoinositide 3-kinase in PIKfyve immune complexes from 3T3-L1 adipocytes.
Molecular and cellular endocrinology 2001;181(1-2):35-46.
2001: Ikonomov O C; Sbrissa D; Shisheva A
Mammalian cell morphology and endocytic membrane homeostasis require enzymatically active phosphoinositide 5-kinase PIKfyve.
The Journal of biological chemistry 2001;276(28):26141-7.
2001: Shisheva A; Rusin B; Ikonomov O C; DeMarco C; Sbrissa D
Localization and insulin-regulated relocation of phosphoinositide 5-kinase PIKfyve in 3T3-L1 adipocytes.
The Journal of biological chemistry 2001;276(15):11859-69.
2001: Shisheva A
PIKfyve: the road to PtdIns 5-P and PtdIns 3,5-P(2).
Cell biology international 2001;25(12):1201-6.
2001: Shisheva A
Antibody and oligonucleotide probes to distinguish intracellular expression and localization patterns of Rab GDP-dissociation inhibitor isoforms.
Methods in enzymology 2001;329():39-50.
2000: Sbrissa D; Ikonomov O C; Shisheva A
PIKfyve lipid kinase is a protein kinase: downregulation of 5'-phosphoinositide product formation by autophosphorylation.
Biochemistry 2000;39(51):15980-9.
2000: Ikonomov O C; Petrov T; Soden K; Shisheva A; Manji H K
Lithium treatment in ovo: effects on embryonic heart rate, natural death of ciliary ganglion neurons, and brain expression of a highly conserved chicken homolog of human MTG8/ETO.
Brain research. Developmental brain research 2000;123(1):13-24.
1999: McEwen R K; Dove S K; Cooke F T; Painter G F; Holmes A B; Shisheva A; Ohya Y; Parker P J; Michell R H
Complementation analysis in PtdInsP kinase-deficient yeast mutants demonstrates that Schizosaccharomyces pombe and murine Fab1p homologues are phosphatidylinositol 3-phosphate 5-kinases.
The Journal of biological chemistry 1999;274(48):33905-12.
1999: Shisheva A; Chinni S R; DeMarco C
General role of GDP dissociation inhibitor 2 in membrane release of Rab proteins: modulations of its functional interactions by in vitro and in vivo structural modifications.
Biochemistry 1999;38(36):11711-21.
1999: Sbrissa D; Ikonomov O C; Shisheva A
PIKfyve, a mammalian ortholog of yeast Fab1p lipid kinase, synthesizes 5-phosphoinositides. Effect of insulin.
The Journal of biological chemistry 1999;274(31):21589-97.
1999: Chinni S R; Shisheva A
Arrest of endosome acidification by bafilomycin A1 mimics insulin action on GLUT4 translocation in 3T3-L1 adipocytes.
The Biochemical journal 1999;339 ( Pt 3)():599-606.
1999: Shisheva A; Sbrissa D; Ikonomov O
Cloning, characterization, and expression of a novel Zn2+-binding FYVE finger-containing phosphoinositide kinase in insulin-sensitive cells.
Molecular and cellular biology 1999;19(1):623-34.
1999: Ikonomov O C; Shisheva A C; Stoynev A G
Circadian clocks and hypertension: genetics and interactions.
Acta physiologica et pharmacologica Bulgarica 1999;24(3):65-70.
1998: Ikonomov O C; Kulesa M C; Shisheva A C; Jacob M H
Innervation and target tissue interactions induce Rab-GDP dissociation inhibitor (GDI) expression during peripheral synapse formation in developing chick ciliary ganglion neurons in situ.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(16):6331-9.
1998: Chinni S R; Brenz M; Shisheva A
Modulation of GDP-dissociation inhibitor protein membrane retention by the cellular redox state in adipocytes.
Experimental cell research 1998;242(1):373-80.
1998: Ikonomov O C; Stoynev A G; Shisheva A C
Integrative coordination of circadian mammalian diversity: neuronal networks and peripheral clocks.
Progress in neurobiology 1998;54(1):87-97.
1997: Shisheva A; Czech M P
Association of cytosolic Rab4 with GDI isoforms in insulin-sensitive 3T3-L1 adipocytes.
Biochemistry 1997;36(22):6564-70.
1995: Shechter Y; Li J; Meyerovitch J; Gefel D; Bruck R; Elberg G; Miller D S; Shisheva A
Insulin-like actions of vanadate are mediated in an insulin-receptor-independent manner via non-receptor protein tyrosine kinases and protein phosphotyrosine phosphatases.
Molecular and cellular biochemistry 1995;153(1-2):39-47.
1995: Shisheva A; Doxsey S J; Buxton J M; Czech M P
Pericentriolar targeting of GDP-dissociation inhibitor isoform 2.
European journal of cell biology 1995;68(2):143-58.
1994: Shisheva A; Buxton J; Czech M P
Differential intracellular localizations of GDP dissociation inhibitor isoforms. Insulin-dependent redistribution of GDP dissociation inhibitor-2 in 3T3-L1 adipocytes.
The Journal of biological chemistry 1994;269(39):23865-8.
1994: Shisheva A; Südhof T C; Czech M P
Cloning, characterization, and expression of a novel GDP dissociation inhibitor isoform from skeletal muscle.
Molecular and cellular biology 1994;14(5):3459-68.
1994: Shisheva A; Shechter Y
A dynamic system for suppression and re-expression of insulin and pervanadate bioresponses in rat adipocytes. Treatment with okadaic acid and staurosporine.
Biochemical pharmacology 1994;47(9):1537-44.
1994: Shisheva A; Ikonomov O; Shechter Y
The protein tyrosine phosphatase inhibitor, pervanadate, is a powerful antidiabetic agent in streptozotocin-treated diabetic rats.
Endocrinology 1994;134(1):507-10.
1994: Ikonomov O C; Stoynev A G; Shisheva A C
Circadian function of suprachiasmatic nuclei: molecular and cellular biology.
Chronobiologia 1994;21(1-2):71-7.
1993: Shisheva A; Shechter Y
Mechanism of pervanadate stimulation and potentiation of insulin-activated glucose transport in rat adipocytes: dissociation from vanadate effect.
Endocrinology 1993;133(4):1562-8.
1993: Shisheva A; Shechter Y
Role of cytosolic tyrosine kinase in mediating insulin-like actions of vanadate in rat adipocytes.
The Journal of biological chemistry 1993;268(9):6463-9.
1993: Shechter Y; Shisheva A
Vanadium salts and the future treatment of diabetes.
Endeavour 1993;17(1):27-31.
1992: Shisheva A; Shechter Y
Quercetin selectively inhibits insulin receptor function in vitro and the bioresponses of insulin and insulinomimetic agents in rat adipocytes.
Biochemistry 1992;31(34):8059-63.
1992: Shisheva A; Gefel D; Shechter Y
Insulinlike effects of zinc ion in vitro and in vivo. Preferential effects on desensitized adipocytes and induction of normoglycemia in streptozocin-induced rats.
Diabetes 1992;41(8):982-8.
1992: Hazum E; Shisheva A; Shechter Y
Preparation and application of radioiodinated sulfhydryl reagents for the covalent labeling of SH-proteins present in minute quantities.
Journal of biochemical and biophysical methods 1992;24(1-2):95-106.
1992: Shisheva A; Shechter Y
A cytosolic protein tyrosine kinase in rat adipocytes.
FEBS letters 1992;300(1):93-6.
1992: Shechter Y; Shisheva A; Lazar R; Libman J; Shanzer A
Hydrophobic carriers of vanadyl ions augment the insulinomimetic actions of vanadyl ions in rat adipocytes.
Biochemistry 1992;31(7):2063-8.
1991: Shisheva A; Leitner O; Shechter Y
A novel approach for evaluating tyrosine kinase activity based on the radioimmunological determination of phosphotyrosine.
Journal of biochemical and biophysical methods 1991;23(4):307-14.
1991: Shisheva A; Shechter Y
Effect of okadaic acid in rat adipocytes: differential stimulation of glucose and lipid metabolism and induction of refractoriness to insulin and vanadate.
Endocrinology 1991;129(5):2279-88.
1991: Ikonomov O C; Shisheva A C; Stoynev A G; Kurtev I V
Peripheral p-chloroamphetamine is an unsuitable probe for investigation of central serotoninergic control on renal renin secretion in the rat.
Physiology & behavior 1991;49(6):1119-28.
1991: Shisheva A C; Dimitrov T; Ikonomov O C
Plasma angiotensin-converting enzyme activity and blood pressure during the first year of life in normotensive and spontaneously hypertensive rat.
Acta physiologica Hungarica 1991;77(2):129-38.
1990: Shisheva A; Stoinev A; Ikonomov O
[A method for determining the angiotensin-converting enzyme activity in the rat hypothalamus and hypophysis]
Eksperimentalna meditsina i morfologiia 1990;29(2):33-41.
1987: Shisheva A C; Ikonomov O C; Stoynev A G; Popova J
Renin release and water-salt balance after central serotonin depletion by p-chlorophenylalanine in Brattleboro and Wistar rats: possible role of ADH.
Endocrinologia experimentalis 1987;21(3):219-28.
1986: Ikonomov O C; Shisheva A C; Stoynev A G; Kurtev I V
Effect on the plasma renin-aldosterone system of lesions to suprachiasmatic nuclei and central serotonin depletion in rats.
Acta physiologica Hungarica 1986;68(2):211-9.
1985: Ikonomov O C; Stoynev A G; Shisheva A C; Tarkolev N T
Effect of constant light and darkness on the circadian rhythms in rats. II. Plasma renin activity and insulin concentration.
Acta physiologica et pharmacologica Bulgarica 1985;11(1):55-61.
1985: Ikonomov O C; Stoynev A G; Vrabchev N C; Shisheva A C; Tarkolev N T
Circadian rhythms of food and 1% NaCl intake, urine and electrolyte excretion, plasma renin activity and insulin concentration in adrenalectomized rats.
Acta physiologica Hungarica 1985;65(2):181-98.
1981: Ikonomov O; Stoynev A G; Shisheva A; Tarkolev N
[Circadian rhythms of plasma renin activity and the plasma concentration of aldosterone and insulin in the rat: effect of renal denervation and food restriction]
Agressologie: revue internationale de physio-biologie et de pharmacologie appliquées aux effets de l'agression 1981;22(6):247-53.
1980: Stoynev A; Ikonomov O; Tarkolev N; Shisheva A
Effects of suprachiasmatic nuclei (SCN) lesions on the circadian variations in PRA and IRI level in the rat.
Acta physiologica Academiae Scientiarum Hungaricae 1980;56(4):431-5.

Sign-in to see more