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Robert Shiu

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Publications

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Anne Blanchard; A Nistor; F E Castaneda; D Martin; Geoffrey G Hicks; Francis M Amara; Robert Shiu; Yvonne Myal
Generation and initial characterization of the prolactin-inducible protein (PIP) null mouse: accompanying global changes in gene expression in the submandibular gland.
Anne Blanchard; Barbara Iwasiow; Alison Yarmill; Agnes Fresnosa; Josef Silha; Yvonne Myal; Leigh C Murphy; Michel Chrétien; Nabil Seidah; Robert Shiu
Targeted production of proprotein convertase PC1 enhances mammary development and tumorigenesis in transgenic mice.
Julieta Werner; Vince P Palace; Christopher Baron; Robert Shiu; Alison Yarmill
A real-time PCR method for the quantification of the two isoforms of metallothionein in Lake Trout (Salvelinus namaycush).

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All Publications

2009: Anne Blanchard; A Nistor; F E Castaneda; D Martin; Geoffrey G Hicks; Francis M Amara; Robert Shiu; Yvonne Myal
Generation and initial characterization of the prolactin-inducible protein (PIP) null mouse: accompanying global changes in gene expression in the submandibular gland.
Canadian journal of physiology and pharmacology 2009;87(10):859-72.
2009: Anne Blanchard; Barbara Iwasiow; Alison Yarmill; Agnes Fresnosa; Josef Silha; Yvonne Myal; Leigh C Murphy; Michel Chrétien; Nabil Seidah; Robert Shiu
Targeted production of proprotein convertase PC1 enhances mammary development and tumorigenesis in transgenic mice.
Canadian journal of physiology and pharmacology 2009;87(10):831-8.
2008: Julieta Werner; Vince P Palace; Christopher Baron; Robert Shiu; Alison Yarmill
A real-time PCR method for the quantification of the two isoforms of metallothionein in Lake Trout (Salvelinus namaycush).
Archives of environmental contamination and toxicology 2008;54(1):84-91.
2007: GEORGIOS SKLIRIS; Anthony Lewis; Ethan D Emberley; Baocheng Peng; Wineeta K Weebadda; Angela Kemp; James Davie; Robert Shiu; Peter H Watson; Leigh C Murphy
Estrogen receptor-beta regulates psoriasin (S100A7) in human breast cancer.
Breast cancer research and treatment 2007;104(1):75-85.
2007: Anne Blanchard; Robert Shiu; Stephanie Booth; Garrett Sorensen; Nicole DeCorby; Andreea Nistor; Paul Wong; Etienne Leygue; Yvonne Myal
Gene expression profiling of early involuting mammary gland reveals novel genes potentially relevant to human breast cancer.
Frontiers in bioscience : a journal and virtual library 2007;12():2221-32.
2006: Anne A A Blanchard; Peter H Watson; Robert Shiu; Etienne Leygue; Andreea Nistor; Paul Wong; Yvonne Myal
Differential expression of claudin 1, 3, and 4 during normal mammary gland development in the mouse.
DNA and cell biology 2006;25(2):79-86.
2005: Leigh C Murphy; Baocheng Peng; Anthony Lewis; James Davie; Etienne Leygue; Angela Kemp; Kanyarat Ung; M Vendetti; Robert Shiu
Inducible upregulation of oestrogen receptor-beta1 affects oestrogen and tamoxifen responsiveness in MCF7 human breast cancer cells.
Journal of molecular endocrinology 2005;34(2):553-66.
2005: Meghan Webb; Ethan D Emberley; Michael Lizardo; Salem Alowami; Gefei Qing; Abdullah Alfia'ar; Linda J Snell-Curtis; Yulian Niu; Alberto Civetta; Yvonne Myal; Robert Shiu; Leigh C Murphy; Peter H Watson
Expression analysis of the mouse S100A7/psoriasin gene in skin inflammation and mammary tumorigenesis.
BMC cancer 2005;5():17.
2004: Geetanjalee Modha; Anne Blanchard; Barbara Iwasiow; Xiao Juan Mao; Sandra Troup; Adewale Adeyinka; Peter Watson; Robert Shiu; Yvonne Myal
Developmental changes in insulin-like growth factor I receptor gene expression in the mouse mammary gland.
Endocrine research 2004;30(1):127-40.
2003: Geetanjalee Modha; Anne Blanchard; Janine Sidorchuk; Marcello Venditti; Robert Shiu; Yvonne Myal
Inducible expression of dominant negative insulin-like growth factor I receptor in MCF-7 breast cancer cells.
Endocrine 2003;22(3):293-303.
2002: Marcello Venditti; Barbara Iwasiow; F William Orr; Robert Shiu
C-myc gene expression alone is sufficient to confer resistance to antiestrogen in human breast cancer cells.
International journal of cancer. Journal international du cancer 2002;99(1):35-42.
2001: M Cheng; N Xu; Barbara Iwasiow; N Seidah; M Chrétien; Robert Shiu
Elevated expression of proprotein convertases alters breast cancer cell growth in response to estrogen and tamoxifen.
Journal of molecular endocrinology 2001;26(2):95-105.
2000: Yvonne Myal; Anne Blanchard; Peter Watson; M Corrin; Robert Shiu; Barbara Iwasiow
Detection of genetic point mutations by peptide nucleic acid-mediated polymerase chain reaction clamping using paraffin-embedded specimens.
Analytical biochemistry 2000;285(1):169-72.
2000: Carl A Peters; RE Cutler; Evelyn T Maizels; MC Robertson; Robert Shiu; P Fields; Mary Hunzicker-Dunn
Regulation of PKC delta expression by estrogen and rat placental lactogen-1 in luteinized rat ovarian granulosa cells.
Molecular and cellular endocrinology 2000;162(1-2):181-91.
2000: Carl A Peters; Evelyn T Maizels; MC Robertson; Robert Shiu; Melvyn S Soloff; Mary Hunzicker-Dunn
Induction of relaxin messenger RNA expression in response to prolactin receptor activation requires protein kinase C delta signaling.
Molecular endocrinology (Baltimore, Md.) 2000;14(4):576-90.
1999: J W Clark; Linda Snell; Robert Shiu; F William Orr; N Maitre; C P Vary; David J Cole; Peter H Watson
The potential role for prolactin-inducible protein (PIP) as a marker of human breast cancer micrometastasis.
British journal of cancer 1999;81(6):1002-8.
1999: G Seyoum; MC Robertson; T V Persaud; J A Paterson; Robert Shiu
Influence of rat placental lactogen-I on the development of whole rat embryos in culture.
The Journal of endocrinology 1999;160(2):231-7.
1998: Yvonne Myal; Barbara Iwasiow; H Cosby; A Yarmill; Anne Blanchard; D Tsuyuki; Agnes Fresnoza; Mary Lynn Duckworth; Robert Shiu
Analysis of tissue- and hormone-specific regulation of the human prolactin-inducible protein/gross cystic disease fluid protein-15 gene in transgenic mice.
Journal of molecular endocrinology 1998;21(2):217-23.
1997: M Cheng; Peter H Watson; J A Paterson; N Seidah; M Chrétien; Robert Shiu
Pro-protein convertase gene expression in human breast cancer.
International journal of cancer. Journal international du cancer 1997;71(6):966-71.
1997: Robert S Bridges; MC Robertson; Robert Shiu; JD Sturgis; B M Henriquez; Phyllis E Mann
Central lactogenic regulation of maternal behavior in rats: steroid dependence, hormone specificity, and behavioral potencies of rat prolactin and rat placental lactogen I.
Endocrinology 1997;138(2):756-63.
1996: MC Robertson; H Cosby; Robert Shiu
Rat placental lactogen-I variant (rPL-Iv), product of an unique gene, is biologically different from rPL-I.
Endocrinology 1996;137(12):5242-9.
1996: Y Myal; B Iwasiow; A Yarmill; Robert Shiu
A new member of the hormonally regulated rodent submaxillary gland glycoprotein gene family: cDNA cloning and tissue specific expression.
Molecular and cellular endocrinology 1996;120(2):133-8.
1996: Audrey W Li; G Seyoum; Robert Shiu; Paul R Murphy
Expression of the rat BFGF antisense RNA transcript is tissue-specific and developmentally regulated.
Molecular and cellular endocrinology 1996;118(1-2):113-23.
1996: D Dubik; Peter H Watson; M Venditti; Robert Shiu
Nuclear oncogenes in breast cancer.
Cancer treatment and research 1996;83():171-89.
1995: C Chakraborty; S Sharma; N Katsumata; Liam J Murphy; I C Schroedter; MC Robertson; Robert Shiu; H G Friesen
Plasma clearance, tissue uptake and expression of pituitary peptide 23/pancreatitis-associated protein in the rat.
The Journal of endocrinology 1995;145(3):461-9.
1995: C Chakraborty; N Katsumata; Y Myal; I C Schroedter; P Brazeau; Liam J Murphy; Robert Shiu; H G Friesen
Age-related changes in peptide-23/pancreatitis-associated protein and pancreatic stone protein/reg gene expression in the rat and regulation by growth hormone-releasing hormone.
Endocrinology 1995;136(5):1843-9.
1995: C A Gregory; Y Myal; Robert Shiu
Rapid genotyping of transgenic mice using dried blood spots from Guthrie cards for PCR analysis.
BioTechniques 1995;18(5):758-60.
1995: N Katsumata; C Chakraborty; Y Myal; I C Schroedter; Liam J Murphy; Robert Shiu; H G Friesen
Molecular cloning and expression of peptide 23, a growth hormone-releasing hormone-inducible pituitary protein.
Endocrinology 1995;136(4):1332-9.
1995: C Chakraborty; M Vrontakis; P Molnar; I C Schroedter; N Katsumata; Liam J Murphy; Robert Shiu; H G Friesen
Expression of pituitary peptide 23 in the rat uterus: regulation by estradiol.
Molecular and cellular endocrinology 1995;108(1-2):149-54.
1994: Susan Kasper; Paul S Rennie; Nicholas Bruchovsky; Patricia C Sheppard; H Cheng; L Lin; Robert Shiu; Rob Snoek; Robert J Matusik
Cooperative binding of androgen receptors to two DNA sequences is required for androgen induction of the probasin gene.
The Journal of biological chemistry 1994;269(50):31763-9.
1994: Y Myal; B Iwasiow; A Yarmill; E Harrison; J A Paterson; Robert Shiu
Tissue-specific androgen-inhibited gene expression of a submaxillary gland protein, a rodent homolog of the human prolactin-inducible protein/GCDFP-15 gene.
Endocrinology 1994;135(4):1605-10.
1994: J A Paterson; Robert Shiu
Basic fibroblast growth factor (bFGF) and two of its receptors, FGFR1 and FGFR2: gene expression in the rat brain during postnatal development as determined by quantitative RT-PCR.
Molecular and cellular endocrinology 1994;104(2):191-200.
1994: MC Robertson; H Cosby; A Fresnoza; Peter A Cattini; Robert Shiu; H G Friesen
Expression, purification, and characterization of recombinant rat placental lactogen-I: a comparison with the native hormone.
Endocrinology 1994;134(1):393-400.
1993: Peter H Watson; JR Safneck; K Le; D Dubik; Robert Shiu
Relationship of c-myc amplification to progression of breast cancer from in situ to invasive tumor and lymph node metastasis.
Journal of the National Cancer Institute 1993;85(11):902-7.
1993: Robert Shiu; Peter H Watson; D Dubik
c-myc oncogene expression in estrogen-dependent and -independent breast cancer.
Clinical chemistry 1993;39(2):353-5.
1992: Peter H Watson; R T Pon; Robert Shiu
Inhibition of cell adhesion to plastic substratum by phosphorothioate oligonucleotide.
Experimental cell research 1992;202(2):391-7.
1992: D Dubik; Robert Shiu
Mechanism of estrogen activation of c-myc oncogene expression.
Oncogene 1992;7(8):1587-94.
1992: A E el-Husseini; J A Paterson; Y Myal; Robert Shiu
PCR detection of the rat brain basic fibroblast growth factor (bFGF) mRNA containing a unique 3' untranslated region.
Biochimica et biophysica acta 1992;1131(3):314-6.
1991: Y Myal; D B Robinson; B Iwasiow; D Tsuyuki; P Wong; Robert Shiu
The prolactin-inducible protein (PIP/GCDFP-15) gene: cloning, structure and regulation.
Molecular and cellular endocrinology 1991;80(1-3):165-75.
1991: Peter H Watson; R T Pon; Robert Shiu
Inhibition of c-myc expression by phosphorothioate antisense oligonucleotide identifies a critical role for c-myc in the growth of human breast cancer.
Cancer research 1991;51(15):3996-4000.
1991: Teresa Zelinski; Gail Coghlan; Y Myal; Robert Shiu; S Philipps; L White; M Lewis
Genetic linkage between the Kell blood group system and prolactin-inducible protein loci: provisional assignment of KEL to chromosome 7.
Annals of human genetics 1991;55(Pt 2):137-40.
1991: Y Myal; Gabriel E Dimattia; C A Gregory; H G Friesen; J L Hamerton; Robert Shiu
A BglII RFLP at the human prolactin gene locus on chromosome 6 (PRL).
Nucleic acids research 1991;19(5):1167.
1990: Catherine K L Too; Robert Shiu; H G Friesen
Cross-linking of G-proteins to the prolactin receptor in rat NB2 lymphoma cells.
Biochemical and biophysical research communications 1990;173(1):48-52.
1989: Y Myal; C A Gregory; C Karpan; J L Hamerton; Robert Shiu
TaqI and RsaI RFLP's at the prolactin inducible protein (PIP) locus on chromosome 7.
Nucleic acids research 1989;17(14):5879.
1989: Y Myal; C Gregory; H Wang; J L Hamerton; Robert Shiu
The gene for prolactin-inducible protein (PIP), uniquely expressed in exocrine organs, maps to chromosome 7.
Somatic cell and molecular genetics 1989;15(3):265-70.
1988: D Dubik; Robert Shiu
Transcriptional regulation of c-myc oncogene expression by estrogen in hormone-responsive human breast cancer cells.
The Journal of biological chemistry 1988;263(25):12705-8.
1988: Robert Shiu; J A Paterson
Characterization of insulin-like growth factor II peptides secreted by explants of neonatal brain and of adult pituitary from rats.
Endocrinology 1988;123(3):1456-60.
1988: Leigh C Murphy; Liam J Murphy; D Dubik; G I Bell; Robert Shiu
Epidermal growth factor gene expression in human breast cancer cells: regulation of expression by progestins.
Cancer research 1988;48(16):4555-60.
1988: Leigh C Murphy; L J Murphy; D Tsuyuki; Mary Lynn Duckworth; Robert Shiu
Cloning and characterization of a cDNA encoding a highly conserved, putative calcium binding protein, identified by an anti-prolactin receptor antiserum.
The Journal of biological chemistry 1988;263(5):2397-401.
1988: Leigh C Murphy; Liam J Murphy; Robert Shiu
Progestin regulation of EGF-receptor mRNA accumulation in T-47D human breast cancer cells.
Biochemical and biophysical research communications 1988;150(1):192-6.
1988: Robert Shiu; Leigh C Murphy; Y Myal; T C Dembinski; D Tsuyuki; B M Iwasiow
Actions of pituitary prolactin and insulin-like growth factor II in human breast cancer.
Cancer treatment and research 1988;40():167-83.
1987: D Dubik; T C Dembinski; Robert Shiu
Stimulation of c-myc oncogene expression associated with estrogen-induced proliferation of human breast cancer cells.
Cancer research 1987;47(24 Pt 1):6517-21.
1987: Leigh C Murphy; D Tsuyuki; Y Myal; Robert Shiu
Isolation and sequencing of a cDNA clone for a prolactin-inducible protein (PIP). Regulation of PIP gene expression in the human breast cancer cell line, T-47D.
The Journal of biological chemistry 1987;262(31):15236-41.
1987: L C Murphy; M Lee-Wing; G J Goldenberg; Robert Shiu
Expression of the gene encoding a prolactin-inducible protein by human breast cancers in vivo: correlation with steroid receptor status.
Cancer research 1987;47(15):4160-4.
1987: Robert Shiu; Leigh C Murphy; D Tsuyuki; Y Myal; M Lee-Wing; B Iwasiow
Biological actions of prolactin in human breast cancer.
Recent progress in hormone research 1987;43():277-303.
1986: Robert Shiu; G Lima; C K Leung; T C Dembinski
Intrinsic and extrinsic factors in estrogen action in human breast cancer: role of polyamines and pituitary factors.
Journal of steroid biochemistry 1986;24(1):133-8.
1985: Robert Shiu; B M Iwasiow
Prolactin-inducible proteins in human breast cancer cells.
The Journal of biological chemistry 1985;260(20):11307-13.
1985: T C Dembinski; C K Leung; Robert Shiu
Evidence for a novel pituitary factor that potentiates the mitogenic effect of estrogen in human breast cancer cells.
Cancer research 1985;45(7):3083-9.
1985: G Lima; Robert Shiu
Role of polyamines in estradiol-induced growth of human breast cancer cells.
Cancer research 1985;45(6):2466-70.
1984: Y Myal; Robert Shiu; B Bhaumick; M Bala
Receptor binding and growth-promoting activity of insulin-like growth factors in human breast cancer cells (T-47D) in culture.
Cancer research 1984;44(12 Pt 1):5486-90.
1982: Y Imai; C K Leung; H G Friesen; Robert Shiu
Epidermal growth factor receptors and effect of epidermal growth factor on growth of human breast cancer cells in long-term tissue culture.
Cancer research 1982;42(11):4394-8.
1982: C K Leung; Robert Shiu
Morphological and proliferative characteristics of human breast tumor cells cultured on plastic and in collagen matrix.
In vitro 1982;18(5):476-82.
1981: C K Leung; Robert Shiu
Required presence of both estrogen and pituitary factors for the growth of human breast cancer cells in athymic nude mice.
Cancer research 1981;41(2):546-51.