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John Shively

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Sridhar Samineni; Zhifang Zhang; John E Shively
Carcinoembryonic antigen-related cell adhesion molecule 1 negatively regulates granulocyte colony-stimulating factor production by breast tumor-associated macrophages that mediate tumor angiogenesis.
Yun Li; John E Shively
CEACAM1 regulates Fas-mediated apoptosis in Jurkat T-cells via its interaction with β-catenin.
Paul J Yazaki; Jan Terje Andersen; Divya Channappa; Junie Chea; Chia-Wei Cheung; Desiree M Crow; Brian Lee; Lin Li; Kelly Davis Orcutt; Erasmus Poku; Andrew Raubitschek; Inger Sandlie; John E Shively; K Dane Wittrup; David Colcher
A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance.

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All Publications

2013: Sridhar Samineni; Zhifang Zhang; John E Shively
Carcinoembryonic antigen-related cell adhesion molecule 1 negatively regulates granulocyte colony-stimulating factor production by breast tumor-associated macrophages that mediate tumor angiogenesis.
International journal of cancer. Journal international du cancer 2013;133(2):394-407.
2013: Yun Li; John E Shively
CEACAM1 regulates Fas-mediated apoptosis in Jurkat T-cells via its interaction with β-catenin.
Experimental cell research 2013;319(8):1061-72.
2013: Paul J Yazaki; Jan Terje Andersen; Divya Channappa; Junie Chea; Chia-Wei Cheung; Desiree M Crow; Brian Lee; Lin Li; Kelly Davis Orcutt; Erasmus Poku; Andrew Raubitschek; Inger Sandlie; John E Shively; K Dane Wittrup; David Colcher
A series of anti-CEA/anti-DOTA bispecific antibody formats evaluated for pre-targeting: comparison of tumor uptake and blood clearance.
Protein engineering, design & selection : PEDS 2013;26(3):187-93.
2013: Zhanhong Wu; Peter S Conti; Joseph M Fox; Matthew Hassink; Lin Li; Zibo Li; Shuanglong Liu; Indu Nair; Ryan Park; John E Shively; Ivan Todorov; Fouad Kandeel
Development and evaluation of 18F-TTCO-Cys40-Exendin-4: a PET probe for imaging transplanted islets.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2013;54(2):244-51.
2013: Hui Zhang; Wolfgang Zimmermann; Andreas Eisenried; John E Shively
Role of CEACAM1 and CEACAM20 in an in vitro model of prostate morphogenesis.
PloS one 2013;8(1):e53359.
2012: Rongze Lu; Hao Pan; John E Shively
CEACAM1 negatively regulates IL-1β production in LPS activated neutrophils by recruiting SHP-1 to a SYK-TLR4-CEACAM1 complex.
PLoS pathogens 2012;8(4):e1002597.
2011: Lin Li; Desiree Crow; Fabio Turatti; James R Bading; Anne-Line Anderson; Erasmus Poku; Paul J Yazaki; Jenny Carmichael; David Leong; Michael P Wheatcroft; Andrew A Raubitschek; Peter J Hudson; David Colcher; David Wheatcroft; John E Shively
Site-specific conjugation of monodispersed DOTA-PEGn to a thiolated diabody reveals the effect of increasing peg size on kidney clearance and tumor uptake with improved 64-copper PET imaging.
Bioconjugate chemistry 2011;22(4):709-16.
2011: Sridhar Samineni; Carlotta Glackin; John E Shively
Role of CEACAM1, ECM, and mesenchymal stem cells in an orthotopic model of human breast cancer.
International journal of breast cancer 2011;2011():381080.
2010: Jeffrey Y C Wong; Andrew Raubitschek; Dave Yamauchi; Lawrence E Williams; Anna M Wu; Paul J Yazaki; John E Shively; David Colcher; George Somlo
A pretherapy biodistribution and dosimetry study of indium-111-radiolabeled trastuzumab in patients with human epidermal growth factor receptor 2-overexpressing breast cancer.
Cancer biotherapy & radiopharmaceuticals 2010;25(4):387-94.
2010: Lin Li; Fabio Turatti; Desiree Crow; James R Bading; Anne-Line Anderson; Erasmus Poku; Paul J Yazaki; Lawrence E Williams; Debra Tamvakis; Paul Sanders; David Leong; Andrew Raubitschek; Peter J Hudson; David Colcher; John E Shively
Monodispersed DOTA-PEG-conjugated anti-TAG-72 diabody has low kidney uptake and high tumor-to-blood ratios resulting in improved 64Cu PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(7):1139-46.
2010: Charng-Jui Chen; Tung Nguyen; John E Shively
Role of calpain-9 and PKC-delta in the apoptotic mechanism of lumen formation in CEACAM1 transfected breast epithelial cells.
Experimental cell research 2010;316(4):638-48.
2010: Zhifang Zhang; John E Shively
Generation of novel bone forming cells (monoosteophils) from the cathelicidin-derived peptide LL-37 treated monocytes.
PloS one 2010;5(11):e13985.
2010: Marieta Gencheva; Charng-Jui Chen; Tung Nguyen; John E Shively
Regulation of CEACAM1 transcription in human breast epithelial cells.
BMC molecular biology 2010;11():79.
2010: Angel Gu; Zhifang Zhang; Nan Zhang; Walter Tsark; John E Shively
Generation of human CEACAM1 transgenic mice and binding of Neisseria Opa protein to their neutrophils.
PloS one 2010;5(4):e10067.
2009: Zhifang Zhang; Gregory Cherryholmes; Frances Chang; David M Rose; Ingrid Schraufstatter; John E Shively
Evidence that cathelicidin peptide LL-37 may act as a functional ligand for CXCR2 on human neutrophils.
European journal of immunology 2009;39(11):3181-94.
2009: Elizabeth O Lobo; Zhifang Zhang; John E Shively
Pivotal advance: CEACAM1 is a negative coreceptor for the B cell receptor and promotes CD19-mediated adhesion of B cells in a PI3K-dependent manner.
Journal of leukocyte biology 2009;86(2):205-18.
2009: Angel Gu; Walter Tsark; Kathryn V Holmes; John E Shively
Role of Ceacam1 in VEGF induced vasculogenesis of murine embryonic stem cell-derived embryoid bodies in 3D culture.
Experimental cell research 2009;315(10):1668-82.
2009: Chunxia Li; Charng-Jui Chen; John E Shively
Mutational analysis of the cytoplasmic domain of CEACAM1-4L in humanized mammary glands reveals key residues involved in lumen formation: stimulation by Thr-457 and inhibition by Ser-461.
Experimental cell research 2009;315(7):1225-33.
2009: Jinong Feng; Zhifang Zhang; Wenyan Li; Xiaoming Shen; Wenjia Song; Chunmei Yang; Frances Chang; Jeff Longmate; Claudia Marek; R Paul St Amand; Theodore G Krontiris; John E Shively; Steve S Sommer
Missense mutations in the MEFV gene are associated with fibromyalgia syndrome and correlate with elevated IL-1beta plasma levels.
PloS one 2009;4(12):e8480.
2009: Ken Dery; Veronica Gusti; Shikha Gaur; John E Shively; Yun Yen; Rajesh K Gaur
Alternative splicing as a therapeutic target for human diseases.
Methods in molecular biology (Clifton, N.J.) 2009;555():127-44.
2008: Munetaka Ozeki; John E Shively
Differential cell fates induced by all-trans retinoic acid-treated HL-60 human leukemia cells.
Journal of leukocyte biology 2008;84(3):769-79.
2008: Zhifang Zhang; Gregory Cherryholmes; Allen Mao; Claudia Marek; Jeffrey Longmate; Michael Kalos; R Paul St Amand; John E Shively
High plasma levels of MCP-1 and eotaxin provide evidence for an immunological basis of fibromyalgia.
Experimental biology and medicine (Maywood, N.J.) 2008;233(9):1171-80.
2008: Zhifang Zhang; Gregory Cherryholmes; John E Shively
Neutrophil secondary necrosis is induced by LL-37 derived from cathelicidin.
Journal of leukocyte biology 2008;84(3):780-8.
2008: Lan Jin; Yun Li; Charng-Jui Chen; Mark A Sherman; Keith Le; John E Shively
Direct interaction of tumor suppressor CEACAM1 with beta catenin: identification of key residues in the long cytoplasmic domain.
Experimental biology and medicine (Maywood, N.J.) 2008;233(7):849-59.
2008: Shikha Gaur; John E Shively; Yun Yen; Rajesh K Gaur
Altered splicing of CEACAM1 in breast cancer: identification of regulatory sequences that control splicing of CEACAM1 into long or short cytoplasmic domain isoforms.
Molecular cancer 2008;7():46.
2008: Lin Li; James Bading; Paul J Yazaki; Amitkumar H Ahuja; Desiree M Crow; David Colcher; Lawrence E Williams; Jeffrey Y C Wong; Andrew Raubitschek; John E Shively
A versatile bifunctional chelate for radiolabeling humanized anti-CEA antibody with In-111 and Cu-64 at either thiol or amino groups: PET imaging of CEA-positive tumors with whole antibodies.
Bioconjugate chemistry 2008;19(1):89-96.
2007: S Yokoyama; C-J Chen; T Nguyen; John E Shively
Role of CEACAM1 isoforms in an in vivo model of mammary morphogenesis: mutational analysis of the cytoplasmic domain of CEACAM1-4S reveals key residues involved in lumen formation.
Oncogene 2007;26(55):7637-46.
2007: Tove Olafsen; Zhennan Gu; Mark A Sherman; Jeffrey V Leyton; Michael E Witkosky; John E Shively; Andrew Raubitschek; Sherie L Morrison; Anna M Wu; Robert E Reiter
Targeting, imaging, and therapy using a humanized antiprostate stem cell antigen (PSCA) antibody.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2007;30(4):396-405.
2007: Charng-Jui Chen; Julia Kirshner; Mark A Sherman; weidong hu; Tung Nguyen; John E Shively
Mutation analysis of the short cytoplasmic domain of the cell-cell adhesion molecule CEACAM1 identifies residues that orchestrate actin binding and lumen formation.
The Journal of biological chemistry 2007;282(8):5749-60.
2007: John E Shively
18F labeling for immuno-PET: where speed and contrast meet.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(2):170-2.
2007: Vania Kenanova; Tove Olafsen; Lawrence E Williams; Nora H Ruel; Jeff Longmate; Paul J Yazaki; John E Shively; David Colcher; Andrew Raubitschek; Anna M Wu
Radioiodinated versus radiometal-labeled anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments: optimal pharmacokinetics for therapy.
Cancer research 2007;67(2):718-26.
2006: Joseph R Reeve; Grace L Rosenquist; David A Keire; Peter Chew; Hugh B Nicholas; Michael T Davis; Terry D Lee; John E Shively; Robert C Backus
Crucial role of position 40 for interactions of CCK-58 revealed by sequence of cat CCK-58.
Biochemical and biophysical research communications 2006;348(3):819-25.
2006: Jeffrey Y C Wong; David Z J Chu; Lawrence E Williams; An Liu; Jiping Zhan; Dave M Yamauchi; Sharon P Wilczynski; Anna M Wu; Paul J Yazaki; John E Shively; Lucille Leong; Andrew Raubitschek
A phase I trial of (90)Y-DOTA-anti-CEA chimeric T84.66 (cT84.66) radioimmunotherapy in patients with metastatic CEA-producing malignancies.
Cancer biotherapy & radiopharmaceuticals 2006;21(2):88-100.
2006: Joseph R Reeve; Rodger A Liddle; John E Shively; Terry D Lee; David A Keire; Peter Chew; Steven R Vigna
Sequence variation outside the "active" region of dog and rabbit cholecystokinin-58 results in bioactivity differences.
Pancreas 2006;32(3):306-13.
2006: Chunxia Li; Mitsuo Kato; Lily Shiue; John E Shively; Manuel Ares; Ren-Jang Lin
Cell type and culture condition-dependent alternative splicing in human breast cancer cells revealed by splicing-sensitive microarrays.
Cancer research 2006;66(4):1990-9.
2006: Lin Li; Paul J Yazaki; Anne-Line Anderson; Desiree M Crow; David Colcher; Anna M Wu; Lawrence E Williams; Jeffrey Y C Wong; Andrew Raubitschek; John E Shively
Improved biodistribution and radioimmunoimaging with poly(ethylene glycol)-DOTA-conjugated anti-CEA diabody.
Bioconjugate chemistry 2006;17(1):68-76.
2005: Tieli Wang; Daniel Tamae; Thomas LeBon; John E Shively; Yun Yen; Jian Jian Li
The role of peroxiredoxin II in radiation-resistant MCF-7 breast cancer cells.
Cancer research 2005;65(22):10338-46.
2005: Desiree M Crow; Lawrence Williams; David Colcher; Jeffrey Y C Wong; Andrew Raubitschek; John E Shively
Combined radioimmunotherapy and chemotherapy of breast tumors with Y-90-labeled anti-Her2 and anti-CEA antibodies with taxol.
Bioconjugate chemistry 2005;16(5):1117-25.
2005: Tove Olafsen; Vania Kenanova; Gobalakrishnan Sundaresan; Anne-Line Anderson; Desiree M Crow; Paul J Yazaki; Lin Li; Michael F Press; Sanjiv S Gambhir; Lawrence E Williams; Jeffrey Y C Wong; Andrew Raubitschek; John E Shively; Anna M Wu
Optimizing radiolabeled engineered anti-p185HER2 antibody fragments for in vivo imaging.
Cancer research 2005;65(13):5907-16.
2005: Sharon P Wilczynski; Yuan-Yuan Chen; Wengang Chen; Stephen B Howell; John E Shively; David S Alberts
Expression and mutational analysis of tyrosine kinase receptors c-kit, PDGFRalpha, and PDGFRbeta in ovarian cancers.
Human pathology 2005;36(3):242-9.
2005: Vania Kenanova; Tove Olafsen; Desiree M Crow; Gobalakrishnan Sundaresan; Murugesan Subbarayan; Nora H Carter; David Ikle; Paul J Yazaki; Arion F Chatziioannou; Sanjiv S Gambhir; Lawrence E Williams; John E Shively; David Colcher; Andrew Raubitschek; Anna M Wu
Tailoring the pharmacokinetics and positron emission tomography imaging properties of anti-carcinoembryonic antigen single-chain Fv-Fc antibody fragments.
Cancer research 2005;65(2):622-31.
2004: John E Shively
CEACAM1 and hyperplastic polyps: new links in the chain of events leading to colon cancer.
Oncogene 2004;23(58):9303-5.
2004: Jeffrey Y C Wong; David Z J Chu; Lawrence E Williams; Dave M Yamauchi; David Ikle; Cheuk S Kwok; An Liu; Sharon P Wilczynski; David Colcher; Paul J Yazaki; John E Shively; Anna M Wu; Andrew Raubitschek
Pilot trial evaluating an 123I-labeled 80-kilodalton engineered anticarcinoembryonic antigen antibody fragment (cT84.66 minibody) in patients with colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(15):5014-21.
2004: Joseph R Reeve; Rodger A Liddle; Douglas C McVey; Steven R Vigna; Travis E Solomon; David A Keire; Grace L Rosenquist; John E Shively; Terry D Lee; Peter Chew; Gary M Green; Tamer Coskun
Identification of nonsulfated cholecystokinin-58 in canine intestinal extracts and its biological properties.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(2):G326-33.
2004: Detlef Schumann; Jie Huang; Patrick E Clarke; Julia Kirshner; Shih-wa Tsai; Verne N Schumaker; John E Shively
Characterization of recombinant soluble carcinoembryonic antigen cell adhesion molecule 1.
Biochemical and biophysical research communications 2004;318(1):227-33.
2004: Paul J Yazaki; Mark A Sherman; John E Shively; David Ikle; Lawrence E Williams; Jeffrey Y C Wong; David Colcher; Anna M Wu; Andrew Raubitschek
Humanization of the anti-CEA T84.66 antibody based on crystal structure data.
Protein engineering, design & selection : PEDS 2004;17(5):481-9.
2004: Tove Olafsen; Giselle J Tan; Chia-Wei Cheung; Paul J Yazaki; Jinha M Park; John E Shively; Lawrence E Williams; Andrew Raubitschek; Michael F Press; Anna M Wu
Characterization of engineered anti-p185HER-2 (scFv-CH3)2 antibody fragments (minibodies) for tumor targeting.
Protein engineering, design & selection : PEDS 2004;17(4):315-23.
2004: Charng-Jui Chen; John E Shively
The cell-cell adhesion molecule carcinoembryonic antigen-related cellular adhesion molecule 1 inhibits IL-2 production and proliferation in human T cells by association with Src homology protein-1 and down-regulates IL-2 receptor.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(6):3544-52.
2004: Julia Kirshner; John Hardy; Sharon P Wilczynski; John E Shively
Cell-cell adhesion molecule CEACAM1 is expressed in normal breast and milk and associates with beta1 integrin in a 3D model of morphogenesis.
Journal of molecular histology 2004;35(3):287-99.
2004: Guozheng Guo; Tieli Wang; Qian Gao; Daniel Tamae; Patty Wong; Tammy Chen; Wei-Chung Chen; John E Shively; Jeffery Y C Wong; Jian Jian Li
Expression of ErbB2 enhances radiation-induced NF-kappaB activation.
Oncogene 2004;23(2):535-45.
2004: Tove Olafsen; Chia-Wei Cheung; Paul J Yazaki; Lin Li; Gobalakrishnan Sundaresan; Sanjiv S Gambhir; Mark A Sherman; Lawrence E Williams; John E Shively; Andrew Raubitschek; Anna M Wu
Covalent disulfide-linked anti-CEA diabody allows site-specific conjugation and radiolabeling for tumor targeting applications.
Protein engineering, design & selection : PEDS 2004;17(1):21-7.
2003: Julia Kirshner; Detlef Schumann; John E Shively
CEACAM1, a cell-cell adhesion molecule, directly associates with annexin II in a three-dimensional model of mammary morphogenesis.
The Journal of biological chemistry 2003;278(50):50338-45.
2003: Jeffrey Y C Wong; Stephen Shibata; Lawrence E Williams; Cheuk S Kwok; An Liu; David Z J Chu; Dave M Yamauchi; Sharon P Wilczynski; David Ikle; Anna M Wu; Paul J Yazaki; John E Shively; James Doroshow; Andrew Raubitschek
A Phase I trial of 90Y-anti-carcinoembryonic antigen chimeric T84.66 radioimmunotherapy with 5-fluorouracil in patients with metastatic colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(16 Pt 1):5842-52.
2003: Gobalakrishnan Sundaresan; Paul J Yazaki; John E Shively; Ronald D Finn; Steven M Larson; Andrew Raubitschek; Lawrence E Williams; Arion F Chatziioannou; Sanjiv S Gambhir; Anna M Wu
124I-labeled engineered anti-CEA minibodies and diabodies allow high-contrast, antigen-specific small-animal PET imaging of xenografts in athymic mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(12):1962-9.
2003: David A Keire; S Vincent Wu; David L Diehl; Peter Chew; Fang-Jen Ho; Michael T Davis; Terry D Lee; John E Shively; John H Walsh; Joseph R Reeve
Rat progastrin processing yields peptides with altered potency at the CCK-B receptor.
Regulatory peptides 2003;113(1-3):115-24.
2003: Joseph R Reeve; David A Keire; Tamer Coskun; Gary M Green; Chris Evans; Fang-Jen Ho; Terry D Lee; Michael T Davis; John E Shively; Travis E Solomon
Synthesis of biologically active canine CCK-58.
Regulatory peptides 2003;113(1-3):71-7.
2003: Jenny Carmichael; Barbara E Power; Thomas P J Garrett; Paul J Yazaki; John E Shively; Andrew A Raubischek; Anna M Wu; Peter J Hudson
The crystal structure of an anti-CEA scFv diabody assembled from T84.66 scFvs in V(L)-to-V(H) orientation: implications for diabody flexibility.
Journal of molecular biology 2003;326(2):341-51.
2003: Julia Kirshner; Charng-Jui Chen; Pingfang Liu; Jie Huang; John E Shively
CEACAM1-4S, a cell-cell adhesion molecule, mediates apoptosis and reverts mammary carcinoma cells to a normal morphogenic phenotype in a 3D culture.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(2):521-6.
2002: Joseph R Reeve; Douglas C McVey; Nigel W Bunnett; Travis E Solomon; David A Keire; Fang-Jen Ho; Michael T Davis; Terry D Lee; John E Shively; Steven R Vigna
Differences in receptor binding and stability to enzymatic digestion between CCK-8 and CCK-58.
Pancreas 2002;25(3):e50-5.
2002: Lin Li; Tove Olafsen; Anne-Line Anderson; Anna Wu; Andrew Raubitschek; John E Shively
Reduction of kidney uptake in radiometal labeled peptide linkers conjugated to recombinant antibody fragments. Site-specific conjugation of DOTA-peptides to a Cys-diabody.
Bioconjugate chemistry 2002;13(5):985-95.
2002: Kenneth Graham; John E Shively
Improved initial yields in C-terminal sequence analysis by thiohydantoin chemistry using purified diphenylphosphoryl isothiocyanate: NMR evidence for a reaction intermediate in the coupling reaction.
Analytical biochemistry 2002;307(2):202-11.
2002: Lin Li; Shih-wa Tsai; Anne-Line Anderson; David A Keire; Andrew Raubitschek; John E Shively
Vinyl sulfone bifunctional derivatives of DOTA allow sulfhydryl- or amino-directed coupling to antibodies. Conjugates retain immunoreactivity and have similar biodistributions.
Bioconjugate chemistry 2002;13(1):110-5.
2001: Detlef Schumann; Charng-Jui Chen; B Kaplan; John E Shively
Carcinoembryonic antigen cell adhesion molecule 1 directly associates with cytoskeleton proteins actin and tropomyosin.
The Journal of biological chemistry 2001;276(50):47421-33.
2001: David A Keire; Yun Hee Jang; L Li; S Dasgupta; William A Goddard; John E Shively
Chelators for radioimmunotherapy: I. NMR and ab initio calculation studies on 1,4,7,10-tetra(carboxyethyl)-1,4,7,10-tetraazacyclododecane (DO4Pr) and 1,4,7-tris(carboxymethyl)-10-(carboxyethyl)-1,4,7,10-tetraazacyclododecane (DO3A1Pr).
Inorganic chemistry 2001;40(17):4310-8.
2001: Paul J Yazaki; LE Shively; C Clark; Chia-Wei Cheung; W Le; BK Szpikowska; John E Shively; Andrew Raubitschek; Anna M Wu
Mammalian expression and hollow fiber bioreactor production of recombinant anti-CEA diabody and minibody for clinical applications.
Journal of immunological methods 2001;253(1-2):195-208.
2001: Lawrence E Williams; B G Beatty; John E Shively; J D Beatty
Accumulation of radiolabeled anti-CEA antibody (mT84.66) in the case of multiple LS174T tumors in a nude mouse model.
Cancer biotherapy & radiopharmaceuticals 2001;16(2):147-57.
2001: MR Lewis; J Y Kao; Anne-Line Anderson; John E Shively; Andrew Raubitschek
An improved method for conjugating monoclonal antibodies with N-hydroxysulfosuccinimidyl DOTA.
Bioconjugate chemistry 2001;12(2):320-4.
2001: Shih-wa Tsai; Lin Li; Lawrence E Williams; Anne-Line Anderson; Andrew Raubitschek; John E Shively
Metabolism and renal clearance of 111In-labeled DOTA-conjugated antibody fragments.
Bioconjugate chemistry 2001;12(2):264-70.
2001: Paul J Yazaki; Anna M Wu; Shih-wa Tsai; Lawrence E Williams; D N Ikler; Jeffrey Y C Wong; John E Shively; Andrew Raubitschek
Tumor targeting of radiometal labeled anti-CEA recombinant T84.66 diabody and t84.66 minibody: comparison to radioiodinated fragments.
Bioconjugate chemistry 2001;12(2):220-8.
2001: Lawrence E Williams; Anna M Wu; Paul J Yazaki; An Liu; Andrew Raubitschek; John E Shively; Jeffrey Y C Wong
Numerical selection of optimal tumor imaging agents with application to engineered antibodies.
Cancer biotherapy & radiopharmaceuticals 2001;16(1):25-35.
2000: David Z J Chu; Dave M Yamauchi; Lawrence E Williams; An Liu; Sharon P Wilczynski; Anna M Wu; John E Shively; James Doroshow; Andrew Raubitschek
A phase I radioimmunotherapy trial evaluating 90yttrium-labeled anti-carcinoembryonic antigen (CEA) chimeric T84.66 in patients with metastatic CEA-producing malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(10):3855-63.
2000: Xin Xu; P Clarke; G Szalai; John E Shively; Lawrence E Williams; Yu Shyr; EG Shi; FJ Primus
Targeting and therapy of carcinoembryonic antigen-expressing tumors in transgenic mice with an antibody-interleukin 2 fusion protein.
Cancer research 2000;60(16):4475-84.
2000: Anna M Wu; Paul J Yazaki; S w Tsai; Khoi Nguyen; Anne-Line Anderson; D W McCarthy; M J Welch; John E Shively; Lawrence E Williams; Andrew Raubitschek; Jeffrey Y C Wong; Tatsushi Toyokuni; Michael E Phelps; Sanjiv S Gambhir
High-resolution microPET imaging of carcinoembryonic antigen-positive xenografts by using a copper-64-labeled engineered antibody fragment.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(15):8495-500.
2000: Shih-wa Tsai; Y Sun; Lawrence E Williams; Andrew Raubitschek; Anna M Wu; John E Shively
Biodistribution and radioimmunotherapy of human breast cancer xenografts with radiometal-labeled DOTA conjugated anti-HER2/neu antibody 4D5.
Bioconjugate chemistry 2000;11(3):327-34.
2000: Jeffrey Y C Wong; J Wang; An Liu; TL Odom-Maryon; John E Shively; Andrew Raubitschek; Lawrence E Williams
Evaluating changes in stable chromosomal translocation frequency in patients receiving radioimmunotherapy.
International journal of radiation oncology, biology, physics 2000;46(3):599-607.
1999: Jeffrey Y C Wong; George Somlo; TL Odom-Maryon; Lawrence E Williams; An Liu; Dave M Yamauchi; Anna M Wu; Paul J Yazaki; Sharon P Wilczynski; John E Shively; Stephen Forman; James Doroshow; Andrew Raubitschek
Initial clinical experience evaluating Yttrium-90-chimeric T84.66 anticarcinoembryonic antigen antibody and autologous hematopoietic stem cell support in patients with carcinoembryonic antigen-producing metastatic breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3224s-3231s.
1999: Michael Neumaier; F J Gaida; M R Lewis; LJ Hefta; LE Shively; A Raubitschek; John E Shively
A chimeric anti-CEA antibody with heavy interchain disulfide bonds deleted: molecular characterization and biodistributions in normal and tumor bearing mice.
Anticancer research 1999;19(1A):13-21.
1998: Jeffrey Y C Wong; David Z J Chu; Dave M Yamauchi; TL Odom-Maryon; Lawrence E Williams; An Liu; J M Esteban; Anna M Wu; FJ Primus; J D Beatty; John E Shively; Andrew Raubitschek
Dose escalation trial of indium-111-labeled anti-carcinoembryonic antigen chimeric monoclonal antibody (chimeric T84.66) in presurgical colorectal cancer patients.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(12):2097-104.
1998: BE Kaplan; LJ Hefta; R C Blake; KM Swiderek; John E Shively
Solid-phase synthesis and characterization of carcinoembryonic antigen (CEA) domains.
The journal of peptide research : official journal of the American Peptide Society 1998;52(4):249-60.
1998: J Huang; J F Simpson; Carlotta A Glackin; L Riethorf; C Wagener; John E Shively
Expression of biliary glycoprotein (CD66a) in normal and malignant breast epithelial cells.
Anticancer research 1998;18(5A):3203-12.
1998: Young-Hyun You; LJ Hefta; Paul J Yazaki; Anna M Wu; John E Shively
Expression, purification, and characterization of a two domain carcinoembryonic antigen minigene (N-A3) in pichia pastoris. The essential role of the N-domain.
Anticancer research 1998;18(5A):3193-201.
1998: LJ Hefta; Michael Neumaier; John E Shively
Kinetic and affinity constants of epitope specific anti-carcinoembryonic antigen (CEA) monoclonal antibodies for CEA and engineered CEA domain constructs.
Immunotechnology : an international journal of immunological engineering 1998;4(1):49-57.
1998: Lawrence E Williams; MR Lewis; GG Bebb; KG Clarke; TL Odom-Maryon; John E Shively; Andrew Raubitschek
Biodistribution of 111In- and 90Y-labeled DOTA and maleimidocysteineamido-DOTA conjugated to chimeric anticarcinoembryonic antigen antibody in xenograft-bearing nude mice: comparison of stable and chemically labile linker systems.
Bioconjugate chemistry 1998;9(1):87-93.
1998: MR Lewis; John E Shively
Maleimidocysteineamido-DOTA derivatives: new reagents for radiometal chelate conjugation to antibody sulfhydryl groups undergo pH-dependent cleavage reactions.
Bioconjugate chemistry 1998;9(1):72-86.
1997: Jeffrey Y C Wong; G E Thomas; Dave M Yamauchi; Lawrence E Williams; TL Odom-Maryon; An Liu; J M Esteban; Michael Neumaier; S Dresse; Anna M Wu; FJ Primus; John E Shively; Andrew Raubitschek
Clinical evaluation of indium-111-labeled chimeric anti-CEA monoclonal antibody.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(12):1951-9.
1996: D Grandt; M Schimiczek; W Rascher; F Feth; John E Shively; T D Lee; M T Davis; Joseph R Reeve; Martin C Michel
Neuropeptide Y 3-36 is an endogenous ligand selective for Y2 receptors.
Regulatory peptides 1996;67(1):33-7.
1996: C J Chen; T T Lin; John E Shively
Role of interferon regulatory factor-1 in the induction of biliary glycoprotein (cell CAM-1) by interferon-gamma.
The Journal of biological chemistry 1996;271(45):28181-8.
1996: S Hu; L Shively; Andrew Raubitschek; M Sherman; Lawrence E Williams; Jeffrey Y C Wong; John E Shively; Anna M Wu
Minibody: A novel engineered anti-carcinoembryonic antigen antibody fragment (single-chain Fv-CH3) which exhibits rapid, high-level targeting of xenografts.
Cancer research 1996;56(13):3055-61.
1996: Joseph R Reeve; Viktor E Eysselein; G Rosenquist; Jörg Zeeh; U Regner; F J Ho; P Chew; M T Davis; Terry D Lee; John E Shively; Scott Brazer; Rodger A Liddle
Evidence that CCK-58 has structure that influences its biological activity.
The American journal of physiology 1996;270(5 Pt 1):G860-8.
1996: Anna M Wu; W Chen; Andrew Raubitschek; Lawrence E Williams; Michael Neumaier; R Fischer; S Z Hu; TL Odom-Maryon; Jeffrey Y C Wong; John E Shively
Tumor localization of anti-CEA single-chain Fvs: improved targeting by non-covalent dimers.
Immunotechnology : an international journal of immunological engineering 1996;2(1):21-36.
1996: KM Swiderek; Terry D Lee; John E Shively
Trace structural analysis of proteins.
Methods in enzymology 1996;271():68-86.
1995: Jeffrey Y C Wong; Lawrence E Williams; Dave M Yamauchi; TL Odom-Maryon; J M Esteban; Michael Neumaier; Anna M Wu; D K Johnson; FJ Primus; John E Shively
Initial experience evaluating 90yttrium-radiolabeled anti-carcinoembryonic antigen chimeric T84.66 in a phase I radioimmunotherapy trial.
Cancer research 1995;55(23 Suppl):5929s-5934s.
1995: C J Chen; L J Li; A Maruya; John E Shively
In vitro and in vivo footprint analysis of the promoter of carcinoembryonic antigen in colon carcinoma cells: effects of interferon gamma treatment.
Cancer research 1995;55(17):3873-82.
1995: J M Bailey; O Tu; G Issai; A Ha; John E Shively
Automated carboxy-terminal sequence analysis of polypeptides containing C-terminal proline.
Analytical biochemistry 1995;224(2):588-96.
1994: M R Lewis; Andrew Raubitschek; John E Shively
A facile, water-soluble method for modification of proteins with DOTA. Use of elevated temperature and optimized pH to achieve high specific activity and high chelate stability in radiolabeled immunoconjugates.
Bioconjugate chemistry 1994;5(6):565-76.
1994: C J Chen; Robert Kane; FJ Primus; G Szalai; M Frederick Hawthorne; John E Shively
Synthesis and characterization of oligomeric nido-carboranyl phosphate diester conjugates to antibody and antibody fragments for potential use in boron neutron capture therapy of solid tumors.
Bioconjugate chemistry 1994;5(6):557-64.
1994: N L Collie; John H Walsh; H C Wong; John E Shively; M T Davis; Terry D Lee; Joseph R Reeve
Purification and sequence of rat oxyntomodulin.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9362-6.
1994: J M Esteban; B Felder; Chul Ahn; JF Simpson; HA Battifora; John E Shively
Prognostic relevance of carcinoembryonic antigen and estrogen receptor status in breast cancer patients.
Cancer 1994;74(5):1575-83.
1994: D Grandt; M Schimiczek; K Struk; John E Shively; Viktor E Eysselein; Harald Goebell; Joseph R Reeve
Characterization of two forms of peptide YY, PYY(1-36) and PYY(3-36), in the rabbit.
Peptides 1994;15(5):815-20.
1993: B G Beatty; R J Paxton; M F Hawthorne; Lawrence E Williams; K J Rickard-Dickson; T Do; John E Shively; J D Beatty
Pharmacokinetics of an anti-carcinoembryonic antigen monoclonal antibody conjugated to a bifunctional transition metal carborane complex (venus flytrap cluster) in tumor-bearing mice.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(8):1294-302.
1993: J M Bailey; M Rusnak; John E Shively
Compact protein sequencer for the C-terminal sequence analysis of peptides and proteins.
Analytical biochemistry 1993;212(2):366-74.
1993: S L Sauter; S M Rutherfurd; Christoph Wagener; John E Shively; S A Hefta
Identification of the specific oligosaccharide sites recognized by type 1 fimbriae from Escherichia coli on nonspecific cross-reacting antigen, a CD66 cluster granulocyte glycoprotein.
The Journal of biological chemistry 1993;268(21):15510-6.
1993: F J Gaida; D Pieper; U W Roder; John E Shively; Christoph Wagener; Michael Neumaier
Molecular characterization of a cloned idiotypic cascade containing a network antigenic determinant specific for the human carcinoembryonic antigen.
The Journal of biological chemistry 1993;268(19):14138-45.
1993: A M Mahrenholz; C H Yeh; John E Shively; S A Hefta
Microsequence and mass spectral analysis of nonspecific cross-reacting antigen 160, a CD15-positive neutrophil membrane glycoprotein. Demonstration of identity with biliary glycoprotein.
The Journal of biological chemistry 1993;268(18):13015-8.
1993: A Stolz; L Hammond; H Lou; Hajime Takikawa; M Ronk; John E Shively
cDNA cloning and expression of the human hepatic bile acid-binding protein. A member of the monomeric reductase gene family.
The Journal of biological chemistry 1993;268(14):10448-57.
1993: N R Shenoy; John E Shively; J M Bailey
Studies in C-terminal sequencing: new reagents for the synthesis of peptidylthiohydantoins.
Journal of protein chemistry 1993;12(2):195-205.
1993: H Takahashi; Y Okai; R J Paxton; LJ Hefta; John E Shively
Differential regulation of carcinoembryonic antigen and biliary glycoprotein by gamma-interferon.
Cancer research 1993;53(7):1612-9.
1992: J M Bailey; F Nikfarjam; N R Shenoy; John E Shively
Automated carboxy-terminal sequence analysis of peptides and proteins using diphenyl phosphoroisothiocyanatidate.
Protein science : a publication of the Protein Society 1992;1(12):1622-33.
1992: LJ Hefta; F S Chen; M Ronk; S L Sauter; V Sarin; S Oikawa; H Nakazato; S Hefta; John E Shively
Expression of carcinoembryonic antigen and its predicted immunoglobulin-like domains in HeLa cells for epitope analysis.
Cancer research 1992;52(20):5647-55.
1992: K J Rutherfurd; KM Swiderek; Carla B Green; Shiuan Chen; John E Shively; S C Kwok
Purification and characterization of PSP-I and PSP-II, two major proteins from porcine seminal plasma.
Archives of biochemistry and biophysics 1992;295(2):352-9.
1992: J M Esteban; Z Warsi; M Haniu; P Hall; John E Shively; Shiuan Chen
Detection of intratumoral aromatase in breast carcinomas. An immunohistochemical study with clinicopathologic correlation.
The American journal of pathology 1992;140(2):337-43.
1992: X W Yan; Jeffrey Y C Wong; J M Esteban; Joseph A Kuhn; B G Beatty; J D Beatty; John E Shively
Effects of recombinant human gamma-interferon on carcinoembryonic antigen expression of human colon cancer cells.
Journal of immunotherapy : official journal of the Society for Biological Therapy 1992;11(2):77-84.
1992: G A Eberlein; Viktor E Eysselein; M T Davis; Terry D Lee; John E Shively; D Grandt; W Niebel; R Williams; J Moessner; Jörg Zeeh
Patterns of prohormone processing. Order revealed by a new procholecystokinin-derived peptide.
The Journal of biological chemistry 1992;267(3):1517-21.
1992: J M Bailey; N R Shenoy; M Ronk; John E Shively
Automated carboxy-terminal sequence analysis of peptides.
Protein science : a publication of the Protein Society 1992;1(1):68-80.
1992: N R Shenoy; J M Bailey; John E Shively
Carboxylic acid-modified polyethylene: a novel support for the covalent immobilization of polypeptides for C-terminal sequencing.
Protein science : a publication of the Protein Society 1992;1(1):58-67.
1991: M Ronk; John E Shively; E A Shute; R C Blake
Amino acid sequence of the blue copper protein rusticyanin from Thiobacillus ferrooxidans.
Biochemistry 1991;30(39):9435-42.
1991: K J Rutherfurd; S A Chen; John E Shively
Affinity labeling of bovine adrenal 3 beta-hydroxysteroid dehydrogenase/steroid isomerase by 5'-[p-(fluorosulfonyl)benzoyl]adenosine.
Biochemistry 1991;30(33):8116-23.
1991: K J Rutherfurd; S A Chen; John E Shively
Isolation and amino acid sequence analysis of bovine adrenal 3 beta-hydroxysteroid dehydrogenase/steroid isomerase.
Biochemistry 1991;30(33):8108-16.
1991: A Stolz; M Rahimi-Kiani; D Ameis; E Chan; M Ronk; John E Shively
Molecular structure of rat hepatic 3 alpha-hydroxysteroid dehydrogenase. A member of the oxidoreductase gene family.
The Journal of biological chemistry 1991;266(23):15253-7.
1991: Joseph R Reeve; Viktor E Eysselein; G A Eberlein; P Chew; F J Ho; V D Huebner; John E Shively; Terry D Lee; Rodger A Liddle
Characterization of canine intestinal cholecystokinin-58 lacking its carboxyl-terminal nonapeptide. Evidence for similar post-translational processing in brain and gut.
The Journal of biological chemistry 1991;266(21):13770-6.
1991: J M Esteban; Joseph A Kuhn; B Felder; Jeffrey Y C Wong; HA Battifora; J D Beatty; P M Wanek; John E Shively
Carcinoembryonic antigen expression of resurgent human colon carcinoma after treatment with therapeutic doses of 90Y-alpha-carcinoembryonic antigen monoclonal antibody.
Cancer research 1991;51(14):3802-6.
1991: V D Huebner; R L Jiang; Terry D Lee; K Legesse; John H Walsh; John E Shively; P Chew; T Azumi; Joseph R Reeve
Purification and structural characterization of progastrin-derived peptides from a human gastrinoma.
The Journal of biological chemistry 1991;266(19):12223-7.
1991: S L Sauter; S M Rutherfurd; Christoph Wagener; John E Shively; S A Hefta
Binding of nonspecific cross-reacting antigen, a granulocyte membrane glycoprotein, to Escherichia coli expressing type 1 fimbriae.
Infection and immunity 1991;59(7):2485-93.
1991: G Mooser; S A Hefta; R J Paxton; John E Shively; Terry D Lee
Isolation and sequence of an active-site peptide containing a catalytic aspartic acid from two Streptococcus sobrinus alpha-glucosyltransferases.
The Journal of biological chemistry 1991;266(14):8916-22.
1991: R J Paxton; B G Beatty; M Frederick Hawthorne; A Varadarajan; Lawrence E Williams; F L Curtis; Carolyn B Knobler; J D Beatty; John E Shively
A transition metal complex (Venus flytrap cluster) for radioimmunodetection and radioimmunotherapy.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3387-91.
1991: T Tressel; J B McCarthy; J Calaycay; Terry D Lee; K Legesse; John E Shively; H Pande
Human plasma fibronectin. Demonstration of structural differences between the A- and B-chains in the III CS region.
The Biochemical journal 1991;274 ( Pt 3)():731-8.
1991: Viktor E Eysselein; Joseph R Reeve; Catia Sternini; Fabio Cominelli; W M Davis; M T Davis; Terry D Lee; F J Ho; D Ridout; John E Shively
Structural characterization of calcitonin gene-related peptide purified from rabbit intestine.
Peptides 1991;12(2):289-95.
1991: Karen Reue; J Zambaux; H Wong; G Lee; T H Leete; M Ronk; John E Shively; B Sternby; B Borgström; D Ameis
cDNA cloning of carboxyl ester lipase from human pancreas reveals a unique proline-rich repeat unit.
Journal of lipid research 1991;32(2):267-76.
1991: J Calaycay; M Rusnak; John E Shively
Microsequence analysis of peptides and proteins. IX. An improved, compact, automated instrument.
Analytical biochemistry 1991;192(1):23-31.
1990: C Wong; S A Hefta; R J Paxton; John E Shively; G Mooser
Size and subdomain architecture of the glucan-binding domain of sucrose:3-alpha-D-glucosyltransferase from Streptococcus sobrinus.
Infection and immunity 1990;58(7):2165-70.
1990: R B Duda; Jeffrey Y C Wong; R J Paxton; B G Beatty; Lawrence E Williams; John E Shively; J D Beatty
Localization of intraperitoneal xenografts of human colon cancer by radiolabeled anti-CEA antibodies.
Journal of surgical oncology 1990;44(2):73-7.
1990: H Schrewe; J Thompson; M Bona; LJ Hefta; A Maruya; M Hassauer; John E Shively; S von Kleist; Wolfgang Zimmermann
Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression.
Molecular and cellular biology 1990;10(6):2738-48.
1990: S A Hefta; R J Paxton; John E Shively
Sequence and glycosylation site identity of two distinct glycoforms of nonspecific cross-reacting antigen as demonstrated by sequence analysis and fast atom bombardment mass spectrometry.
The Journal of biological chemistry 1990;265(15):8618-26.
1990: LJ Hefta; H Schrewe; J A Thompson; S Oikawa; H Nakazato; John E Shively
Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products.
Cancer research 1990;50(8):2397-403.
1990: Michael Neumaier; L Shively; F S Chen; F J Gaida; C Ilgen; R J Paxton; John E Shively; Arthur D Riggs
Cloning of the genes for T84.66, an antibody that has a high specificity and affinity for carcinoembryonic antigen, and expression of chimeric human/mouse T84.66 genes in myeloma and Chinese hamster ovary cells.
Cancer research 1990;50(7):2128-34.
1990: J M Bailey; John E Shively
Carboxy-terminal sequencing: formation and hydrolysis of C-terminal peptidylthiohydantoins.
Biochemistry 1990;29(12):3145-56.
1990: J D Beatty; Lawrence E Williams; Dave M Yamauchi; B A Morton; L R Hill; B G Beatty; R J Paxton; B Merchant; John E Shively
Presurgical imaging with indium-labeled anti-carcinoembryonic antigen for colon cancer staging.
Cancer research 1990;50(3 Suppl):922s-926s.
1990: Lawrence E Williams; B G Beatty; J D Beatty; Jeffrey Y C Wong; R J Paxton; John E Shively
Estimation of monoclonal antibody-associated 90Y activity needed to achieve certain tumor radiation doses in colorectal cancer patients.
Cancer research 1990;50(3 Suppl):1029s-1030s.
1989: M Haniu; M E McManus; D J Birkett; Terry D Lee; John E Shively
Structural and functional analysis of NADPH-cytochrome P-450 reductase from human liver: complete sequence of human enzyme and NADPH-binding sites.
Biochemistry 1989;28(21):8639-45.
1989: Jeffrey Y C Wong; Nahid F Mivechi; R J Paxton; Lawrence E Williams; B G Beatty; J D Beatty; John E Shively
The effects of hyperthermia on tumor carcinoembryonic antigen expression.
International journal of radiation oncology, biology, physics 1989;17(4):803-8.
1989: Denis POMPON; R Y Liu; M J Besman; P L Wang; John E Shively; Shiuan Chen
Expression of human placental aromatase in Saccharomyces cerevisiae.
Molecular endocrinology (Baltimore, Md.) 1989;3(9):1477-87.
1989: G A Eberlein; Viktor E Eysselein; M Schaeffer; Peter Layer; D Grandt; Harald Goebell; W Niebel; M Davis; Terry D Lee; John E Shively
A new molecular form of PYY: structural characterization of human PYY(3-36) and PYY(1-36).
Peptides 1989;10(4):797-803.
1989: M J Besman; K Yanagibashi; Terry D Lee; M Kawamura; P F Hall; John E Shively
Identification of des-(Gly-Ile)-endozepine as an effector of corticotropin-dependent adrenal steroidogenesis: stimulation of cholesterol delivery is mediated by the peripheral benzodiazepine receptor.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(13):4897-901.
1989: X F Liu; H Yuan; M Haniu; T Iyanagi; John E Shively; S A Chen
Reaction of rat liver DT-diaphorase (NAD(P)H:quinone acceptor reductase) with 5'-[p-(fluorosulfonyl)benzoyl]-adenosine.
Molecular pharmacology 1989;35(6):818-22.
1989: S Vincent Wu; P Chew; F J Ho; John H Walsh; Helen Wong; Terry D Lee; M T Davis; John E Shively; Joseph R Reeve
Characterization of the carboxyl terminal flanking peptide of rat progastrin.
Biochemical and biophysical research communications 1989;161(1):69-74.
1989: B G Beatty; J D Beatty; Lawrence E Williams; R J Paxton; John E Shively; M O'Connor-Tressel
Effect of specific antibody pretreatment on liver uptake of 111In-labeled anticarcinoembryonic antigen monoclonal antibody in nude mice bearing human colon cancer xenografts.
Cancer research 1989;49(6):1587-94.
1989: Jeffrey Y C Wong; Lawrence E Williams; L R Hill; R J Paxton; B G Beatty; John E Shively; J D Beatty
The effects of tumor mass, tumor age, and external beam radiation on tumor-specific antibody uptake.
International journal of radiation oncology, biology, physics 1989;16(3):715-20.
1989: J A Thompson; E M Mauch; F S Chen; Y Hinoda; H Schrewe; B Berling; S Barnert; S von Kleist; John E Shively; Wolfgang Zimmermann
Analysis of the size of the carcinoembryonic antigen (CEA) gene family: isolation and sequencing of N-terminal domain exons.
Biochemical and biophysical research communications 1989;158(3):996-1004.
1989: Joseph R Reeve; F Cuttitta; Steven R Vigna; V Heubner; Terry D Lee; John E Shively; F J Ho; J Fedorko; J D Minna; John H Walsh
Multiple gastrin-releasing peptide gene-associated peptides are produced by a human small cell lung cancer line.
The Journal of biological chemistry 1989;264(4):1928-32.
1989: J D Beatty; D M Hyams; B A Morton; B G Beatty; Lawrence E Williams; Dave M Yamauchi; B Merchant; R J Paxton; John E Shively
Impact of radiolabeled antibody imaging on management of colon cancer.
American journal of surgery 1989;157(1):13-9.
1989: S A Chen; M J Besman; John E Shively; K Yanagibashi; P F Hall
Human aromatase.
Drug metabolism reviews 1989;20(2-4):511-7.
1988: K L Cox; G L Rosenquist; Christine K Iwahashi; W F Benisek; Joseph R Reeve; John E Shively; T Lee; V D Huebner
Identification of serotonin from rabbit upper stomach as a stimulant of in vitro gallbladder contraction.
Biochimica et biophysica acta 1988;967(3):364-72.
1988: C M Turkelson; Travis E Solomon; L Bussjaeger; J Turkelson; M Ronk; John E Shively; F J Ho; Joseph R Reeve
Chemical characterization of rat cholecystokinin-58.
Peptides 1988;9(6):1255-60.
1988: T Tressel; John E Shively; H Pande
Human placental fibronectin: demonstration of structural differences between the A and B chains in the extra domain-A region.
Archives of biochemistry and biophysics 1988;266(2):639-43.
1988: B A Morton; M O'Connor-Tressel; B G Beatty; John E Shively; J D Beatty
Artifactual CEA elevation due to human anti-mouse antibodies.
Archives of surgery (Chicago, Ill. : 1960) 1988;123(10):1242-6.
1988: M Haniu; H Yuan; S A Chen; T Iyanagi; Terry D Lee; John E Shively
Structure-function relationship of NAD(P)H:quinone reductase: characterization of NH2-terminal blocking group and essential tyrosine and lysine residues.
Biochemistry 1988;27(18):6877-83.
1988: M Haniu; John E Shively
Microsequence analysis of peptides and proteins. IX. Manual gas-phase microsequencing of multiple samples.
Analytical biochemistry 1988;173(2):296-306.
1988: Y Hinoda; Michael Neumaier; S A Hefta; Z Drzeniek; Christoph Wagener; L Shively; LJ Hefta; John E Shively; R J Paxton
Molecular cloning of a cDNA coding biliary glycoprotein I: primary structure of a glycoprotein immunologically crossreactive with carcinoembryonic antigen.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(18):6959-63.
1988: S A Hefta; LJ Hefta; Terry D Lee; R J Paxton; John E Shively
Carcinoembryonic antigen is anchored to membranes by covalent attachment to a glycosylphosphatidylinositol moiety: identification of the ethanolamine linkage site.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4648-52.
1988: R Jiang; V D Huebner; Terry D Lee; P Chew; F J Ho; John E Shively; John H Walsh; Joseph R Reeve
Isolation and characterization of rabbit gastrin.
Peptides 1988;9(4):763-9.
1988: Wolfgang Zimmermann; B Weber; B Ortlieb; F Rudert; W Schempp; Heinz-Herbert Fiebig; John E Shively; S von Kleist; J A Thompson
Chromosomal localization of the carcinoembryonic antigen gene family and differential expression in various tumors.
Cancer research 1988;48(9):2550-4.
1988: Q Y Xu; John E Shively
Microsequence analysis of peptides and proteins. VIII. Improved electroblotting of proteins onto membranes and derivatized glass-fiber sheets.
Analytical biochemistry 1988;170(1):19-30.
1988: Michael Neumaier; W Zimmermann; L Shively; Y Hinoda; Arthur D Riggs; John E Shively
Characterization of a cDNA clone for the nonspecific cross-reacting antigen (NCA) and a comparison of NCA and carcinoembryonic antigen.
The Journal of biological chemistry 1988;263(7):3202-7.
1988: S A Chen; M J Besman; RS Sparkes; S Zollman; I Klisak; T Mohandas; P F Hall; John E Shively
Human aromatase: cDNA cloning, Southern blot analysis, and assignment of the gene to chromosome 15.
DNA (Mary Ann Liebert, Inc.) 1988;7(1):27-38.
1988: Lawrence E Williams; R B Duda; R T Proffitt; B G Beatty; J D Beatty; Jeffrey Y C Wong; John E Shively; R J Paxton
Tumor uptake as a function of tumor mass: a mathematic model.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1988;29(1):103-9.
1988: Joseph R Reeve; F Cuttitta; Steven R Vigna; John E Shively; John H Walsh
Processing of mammalian preprogastrin-releasing peptide.
Annals of the New York Academy of Sciences 1988;547():21-9.
1987: D H Hawke; H W Lahm; John E Shively; C W Todd
Microsequence analysis of peptides and proteins: trimethylsilylisothiocyanate as a reagent for COOH-terminal sequence analysis.
Analytical biochemistry 1987;166(2):298-307.
1987: J D Beatty; V J Philben; B G Beatty; Lawrence E Williams; R J Paxton; John E Shively; R B Duda; W G Vlahos; J L Werner; K Sheibani
Imaging of colon carcinoma with 111-indium-labeled anti-CEA monoclonal antibodies (Indacea) prior to surgery.
Journal of surgical oncology 1987;36(2):98-104.
1987: John E Shively; P Miller; M Ronk
Microsequence analysis of peptides and proteins. VI. A continuous flow reactor for sample concentration and sequence analysis.
Analytical biochemistry 1987;163(2):517-29.
1987: Osnat Ben-Zeev; C M Ben-Avram; H Wong; J Nikazy; John E Shively; Michael C Schotz
Hepatic lipase: a member of a family of structurally related lipases.
Biochimica et biophysica acta 1987;919(1):13-20.
1987: J A Thompson; H Pande; R J Paxton; L Shively; A Padma; R L Simmer; C W Todd; Arthur D Riggs; John E Shively
Molecular cloning of a gene belonging to the carcinoembryonic antigen gene family and discussion of a domain model.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(9):2965-9.
1987: John E Shively; Joseph R Reeve; V E Eysselein; C Ben-Avram; S R Vigna; John H Walsh
CCK-5: sequence analysis of a small cholecystokinin from canine brain and intestine.
The American journal of physiology 1987;252(2 Pt 1):G272-5.
1987: R J Paxton; G Mooser; H Pande; Terry D Lee; John E Shively
Sequence analysis of carcinoembryonic antigen: identification of glycosylation sites and homology with the immunoglobulin supergene family.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(4):920-4.
1987: H Pande; J Calaycay; T D Lee; K Legesse; John E Shively; Annalisa Siri; Laura Borsi; Luciano Zardi
Demonstration of structural differences between the two subunits of human-plasma fibronectin in the carboxy-terminal heparin-binding domain.
European journal of biochemistry / FEBS 1987;162(2):403-11.
1987: Yoko Fujita-Yamaguchi; D H Hawke; John E Shively; S Choi
Partial amino acid sequence analyses of human placental insulin receptor.
Protein sequences & data analysis 1987;1(1):3-6.
1986: Joseph R Reeve; V Eysselein; John H Walsh; C M Ben-Avram; John E Shively
New molecular forms of cholecystokinin. Microsequence analysis of forms previously characterized by chromatographic methods.
The Journal of biological chemistry 1986;261(35):16392-7.
1986: M Haniu; T Iyanagi; P Miller; Terry D Lee; John E Shively
Complete amino acid sequence of NADPH-cytochrome P-450 reductase from porcine hepatic microsomes.
Biochemistry 1986;25(24):7906-11.
1986: B G Beatty; R J Paxton; K Sheibani; R B Duda; Lawrence E Williams; John E Shively; J D Beatty
Testis imaging with 111In-labeled anticarcinoembryonic antigen monoclonal antibody: identification of carcinoembryonic antigen in normal germ cells.
Cancer research 1986;46(12 Pt 1):6503-8.
1986: J D Beatty; R B Duda; Lawrence E Williams; K Sheibani; R J Paxton; B G Beatty; V J Philben; J L Werner; John E Shively; W G Vlahos
Preoperative imaging of colorectal carcinoma with 111In-labeled anticarcinoembryonic antigen monoclonal antibody.
Cancer research 1986;46(12 Pt 1):6494-502.
1986: T Iyanagi; M Haniu; K Sogawa; Y Fujii-Kuriyama; S Watanabe; John E Shively; K F Anan
Cloning and characterization of cDNA encoding 3-methylcholanthrene inducible rat mRNA for UDP-glucuronosyltransferase.
The Journal of biological chemistry 1986;261(33):15607-14.
1986: R B Duda; J D Beatty; K Sheibani; Lawrence E Williams; R J Paxton; B G Beatty; John E Shively; W G Vlahos; J L Werner; M M Kemeny
Imaging of human colorectal adenocarcinoma with indium-labeled anticarcinoembryonic antigen monoclonal antibody.
Archives of surgery (Chicago, Ill. : 1960) 1986;121(11):1315-9.
1986: M H Mogard; Joseph R Reeve; John E Shively; C M Ben-Avram; V E Eysselein; John H Walsh
Isolation and characterization of a neurotensin-like decapeptide from a canine upper small intestinal extract.
Regulatory peptides 1986;14(4):313-21.
1986: C M Ben-Avram; Osnat Ben-Zeev; T D Lee; K Haaga; John E Shively; J Goers; M E Pedersen; Joseph R Reeve; Michael C Schotz
Homology of lipoprotein lipase to pancreatic lipase.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(12):4185-9.
1986: V J Philben; J G Jakowatz; B G Beatty; W G Vlahos; R J Paxton; Lawrence E Williams; John E Shively; J D Beatty
The effect of tumor CEA content and tumor size on tissue uptake of indium 111-labeled anti-CEA monoclonal antibody.
Cancer 1986;57(3):571-6.
1985: J G Jakowatz; B G Beatty; W G Vlahos; D Porudominsky; V J Philben; Lawrence E Williams; R J Paxton; John E Shively; J D Beatty
High-specific-activity 111In-labeled anticarcinoembryonic antigen monoclonal antibody: biodistribution and imaging in nude mice bearing human colon cancer xenografts.
Cancer research 1985;45(11 Pt 2):5700-6.
1985: R J Paxton; J G Jakowatz; J D Beatty; B G Beatty; W G Vlahos; Lawrence E Williams; B R Clark; John E Shively
High-specific-activity 111In-labeled anticarcinoembryonic antigen monoclonal antibody: improved method for the synthesis of diethylenetriaminepentaacetic acid conjugates.
Cancer research 1985;45(11 Pt 2):5694-9.
1985: J Calaycay; H Pande; T Lee; Laura Borsi; Annalisa Siri; John E Shively; Luciano Zardi
Primary structure of a DNA- and heparin-binding domain (Domain III) in human plasma fibronectin.
The Journal of biological chemistry 1985;260(22):12136-41.
1985: Joseph R Reeve; F J Ho; John H Walsh; C M Ben-Avram; John E Shively
Rapid high-yield purification of canine intestinal motilin and its complete sequence determination.
Journal of chromatography 1985;321(2):421-32.
1985: M Haniu; T Iyanagi; P Miller; John E Shively
Amino acid sequence of COOH-terminal 20K Da fragment from pig liver microsomal NADPH-cytochrome P-450 reductase.
Biochemical and biophysical research communications 1985;127(1):94-8.
1985: H Pande; J Calaycay; D Hawke; C M Ben-Avram; John E Shively
Primary structure of a glycosylated DNA-binding domain in human plasma fibronectin.
The Journal of biological chemistry 1985;260(4):2301-6.
1984: M Haniu; T Iyanagi; K Legesse; John E Shively
Structural analysis of NADPH-cytochrome P-450 reductase from porcine hepatic microsomes. Sequences of proteolytic fragments, cysteine-containing peptides, and a NADPH-protected cysteine peptide.
The Journal of biological chemistry 1984;259(22):13703-11.
1984: M S Orloff; Joseph R Reeve; C M Ben-Avram; John E Shively; John H Walsh
Isolation and sequence analysis of human bombesin-like peptides.
Peptides 1984;5(5):865-70.
1984: B C Zhu; S F Fisher; H Pande; J Calaycay; John E Shively; Roger Laine
Human placental (fetal) fibronectin: increased glycosylation and higher protease resistance than plasma fibronectin. Presence of polylactosamine glycopeptides and properties of a 44-kilodalton chymotryptic collagen-binding domain: difference from human plasma fibronectin.
The Journal of biological chemistry 1984;259(6):3962-70.
1983: B S Rothman; E Mayeri; R O Brown; P M Yuan; John E Shively
Primary structure and neuronal effects of alpha-bag cell peptide, a second candidate neurotransmitter encoded by a single gene in bag cell neurons of Aplysia.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(18):5753-7.