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Elizabeth Shores

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T-Lymphocyte Subsets

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Connie L Sommers; Jan Lee; Kevin L Steiner; Jordan M Gurson; Corinne L Depersis; Dalal El-Khoury; Claudette L Fuller; Elizabeth W Shores; Paul E Love; Lawrence E Samelson
Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection.
Sandra M Hayes; Elizabeth W Shores; Paul E Love
An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors.
Connie L Sommers; Cheung-Seog Park; Jan Lee; Chiguang Feng; Claudette L Fuller; Alexander Grinberg; Jay A Hildebrand; Emanuela Lacaná; Rashmi K Menon; Elizabeth W Shores; Lawrence E Samelson; Paul E Love
A LAT mutation that inhibits T cell development yet induces lymphoproliferation.

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All Publications

2005: Connie L Sommers; Jan Lee; Kevin L Steiner; Jordan M Gurson; Corinne L Depersis; Dalal El-Khoury; Claudette L Fuller; Elizabeth W Shores; Paul E Love; Lawrence E Samelson
Mutation of the phospholipase C-gamma1-binding site of LAT affects both positive and negative thymocyte selection.
The Journal of experimental medicine 2005;201(7):1125-34.
2003: Sandra M Hayes; Elizabeth W Shores; Paul E Love
An architectural perspective on signaling by the pre-, alphabeta and gammadelta T cell receptors.
Immunological reviews 2003;191():28-37.
2002: Connie L Sommers; Cheung-Seog Park; Jan Lee; Chiguang Feng; Claudette L Fuller; Alexander Grinberg; Jay A Hildebrand; Emanuela Lacaná; Rashmi K Menon; Elizabeth W Shores; Lawrence E Samelson; Paul E Love
A LAT mutation that inhibits T cell development yet induces lymphoproliferation.
Science (New York, N.Y.) 2002;296(5575):2040-3.
2002: Chiguang Feng; Kenneth Jeffrey Woodside; Barbara A Vance; Dalal El-Khoury; Matilde Canelles; Jan Lee; Ronald Gress; BJ Fowlkes; Elizabeth W Shores; Paul E Love
A potential role for CD69 in thymocyte emigration.
International immunology 2002;14(6):535-44.
2001: Hala S Azzam; JB DeJarnette; K Huang; R Emmons; C S Park; Connie L Sommers; Dalal El-Khoury; Elizabeth W Shores; Paul E Love
Fine tuning of TCR signaling by CD5.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(9):5464-72.
2000: Connie L Sommers; JB DeJarnette; K Huang; Jan Lee; Dalal El-Khoury; Elizabeth W Shores; Paul E Love
Function of CD3 epsilon-mediated signals in T cell development.
The Journal of experimental medicine 2000;192(6):913-19.
2000: Paul E Love; Jan Lee; Elizabeth W Shores
Critical relationship between TCR signaling potential and TCR affinity during thymocyte selection.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(6):3080-7.
2000: Paul E Love; Elizabeth W Shores
ITAM multiplicity and thymocyte selection: how low can you go?
Immunity 2000;12(6):591-7.
2000: Melanie S Vacchio; Elizabeth W Shores
Flow cytometric analysis of murine T lymphocytes. A practical guide.
Methods in molecular biology (Clifton, N.J.) 2000;134():153-76.
1998: Hala S Azzam; Alexander Grinberg; K Lui; H Shen; Elizabeth W Shores; Paul E Love
CD5 expression is developmentally regulated by T cell receptor (TCR) signals and TCR avidity.
The Journal of experimental medicine 1998;188(12):2301-11.
1998: JB DeJarnette; Connie L Sommers; K Huang; Kenneth Jeffrey Woodside; R Emmons; K Katz; Elizabeth W Shores; Paul E Love
Specific requirement for CD3epsilon in T cell development.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14909-14.
1998: Llewellyn H Mason; Jami Willette-Brown; Stephen K Anderson; P Gosselin; Elizabeth W Shores; Paul E Love; John R Ortaldo; Daniel W McVicar
Characterization of an associated 16-kDa tyrosine phosphoprotein required for Ly-49D signal transduction.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(9):4148-52.
1998: Elizabeth W Shores; M Ono; T Kawabe; Connie L Sommers; T Tran; K Lui; M C Udey; J Ravetch; Paul E Love
T cell development in mice lacking all T cell receptor zeta family members (Zeta, eta, and FcepsilonRIgamma).
The Journal of experimental medicine 1998;187(7):1093-101.
1998: Nicolai S C van Oers; Paul E Love; Elizabeth W Shores; Arthur Weiss
Regulation of TCR signal transduction in murine thymocytes by multiple TCR zeta-chain signaling motifs.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):163-70.
1997: Elizabeth W Shores; V Flamand; T Tran; A Grinberg; Jean-Pierre Kinet; Paul E Love
Fc epsilonRI gamma can support T cell development and function in mice lacking endogenous TCR zeta-chain.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(1):222-30.
1997: Elizabeth W Shores; Paul E Love
TCR zeta chain in T cell development and selection.
Current opinion in immunology 1997;9(3):380-9.
1997: Elizabeth W Shores; T Tran; Alexander Grinberg; Connie L Sommers; H Shen; Paul E Love
Role of the multiple T cell receptor (TCR)-zeta chain signaling motifs in selection of the T cell repertoire.
The Journal of experimental medicine 1997;185(5):893-900.
1996: V Flamand; Elizabeth W Shores; T Tran; K Huang; E Lee; Alexander Grinberg; J P Kinet; Paul E Love
Delayed maturation of CD4- CD8- Fc gamma RII/III+ T and natural killer cell precursors in Fc epsilon RI gamma transgenic mice.
The Journal of experimental medicine 1996;184(5):1725-35.
1996: R Khattri; Anne I Sperling; D Qian; F W Fitch; Elizabeth W Shores; Paul E Love; Jeffrey A Bluestone
TCR-gamma delta cells in CD3 zeta-deficient mice contain Fc epsilon RI gamma in the receptor complex but are specifically unresponsive to antigen.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(6):2320-7.
1996: B Combadière; M Freedman; L Chen; Elizabeth W Shores; Paul E Love; Michael J Lenardo
Qualitative and quantitative contributions of the T cell receptor zeta chain to mature T cell apoptosis.
The Journal of experimental medicine 1996;183(5):2109-17.
1996: Elizabeth W Shores; Paul E Love
Insights into T cell development and signal transduction provided by TCR-zeta chain deficient mice.
International reviews of immunology 1996;13(4):301-15.
1995: Warren J Leonard; Elizabeth W Shores; Paul E Love
Role of the common cytokine receptor gamma chain in cytokine signaling and lymphoid development.
Immunological reviews 1995;148():97-114.
1995: Connie L Sommers; K Huang; Elizabeth W Shores; Alexander Grinberg; D A Charlick; C A Kozak; Paul E Love
Murine txk: a protein tyrosine kinase gene regulated by T cell activation.
Oncogene 1995;11(2):245-51.
1995: X Cao; Elizabeth W Shores; J Hu-Li; M R Anver; B L Kelsall; S M Russell; John Drago; M Noguchi; Alexander Grinberg; Eda T Bloom
Defective lymphoid development in mice lacking expression of the common cytokine receptor gamma chain.
Immunity 1995;2(3):223-38.
1994: Elizabeth W Shores; K Huang; T Tran; E Lee; Alexander Grinberg; Paul E Love
Role of TCR zeta chain in T cell development and selection.
Science (New York, N.Y.) 1994;266(5187):1047-50.
1994: Paul E Love; Elizabeth W Shores; E J Lee; Alexander Grinberg; T I Munitz; Heiner Westphal; Alfred Singer
Differential effects of zeta and eta transgenes on early alpha/beta T cell development.
The Journal of experimental medicine 1994;179(5):1485-94.
1993: Paul E Love; Elizabeth W Shores; M D Johnson; Michel L Tremblay; E J Lee; Alexander Grinberg; S P Huang; Alfred Singer; Heiner Westphal
T cell development in mice that lack the zeta chain of the T cell antigen receptor complex.
Science (New York, N.Y.) 1993;261(5123):918-21.