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Michael Shuler

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TOP 3
Michael L Shuler
Modeling life.
Michael L Shuler; Jong Hwan Sung
Introduction to the special issue on micro- and nanofabrication techniques.
Beum Jun Kim; Jinpian Diao; Michael L Shuler
Mini-scale bioprocessing systems for highly parallel animal cell cultures.

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All Publications

2012: Michael L Shuler
Modeling life.
Annals of biomedical engineering 2012;40(7):1399-407.
2012: Michael L Shuler; Jong Hwan Sung
Introduction to the special issue on micro- and nanofabrication techniques.
Annals of biomedical engineering 2012;40(6):1209-10.
2012: Beum Jun Kim; Jinpian Diao; Michael L Shuler
Mini-scale bioprocessing systems for highly parallel animal cell cultures.
Biotechnology progress 2012;28(3):595-607.
2012: Hui Xu; Jun Wu; Chih-Chang Chu; Michael L Shuler
Development of disposable PDMS micro cell culture analog devices with photopolymerizable hydrogel encapsulating living cells.
Biomedical microdevices 2012;14(2):409-18.
2012: Michael L Shuler; Patricia Foley; Jordan Atlas
Modeling a minimal cell.
Methods in molecular biology (Clifton, N.J.) 2012;881():573-610.
2012: Beum Jun Kim; Lincoln Young; Ti Zhao; Peng Zhou; Michael L Shuler
Batch, fed-batch, and microcarrier cultures with CHO cell lines in a pressure-cycle driven miniaturized bioreactor.
Biotechnology and bioengineering 2012;109(1):137-45.
2011: Alexis J Torres; Charles Zhu; Michael L Shuler; Susan Pannullo
Paclitaxel delivery to brain tumors from hydrogels: a computational study.
Biotechnology progress 2011;27(5):1478-87.
2011: Gilda Shayan; Michael L Shuler; Kelvin H Lee
The effect of astrocytes on the induction of barrier properties in aortic endothelial cells.
Biotechnology progress 2011;27(4):1137-45.
2011: Jong Hwan Sung; Jiajie Yu; Dan Luo; Michael L Shuler; John C March
Microscale 3-D hydrogel scaffold for biomimetic gastrointestinal (GI) tract model.
Lab on a chip 2011;11(3):389-92.
2011: Iman A El Gheriany; Daniela Bocioaga; Anthony G Hay; William C Ghiorse; Michael L Shuler; Leonard W Lion
An uncertain role for Cu(II) in stimulating Mn(II) oxidation by Leptothrix discophora SS-1.
Archives of microbiology 2011;193(2):89-93.
2011: Gilda Shayan; Yong Seok Choi; Eric V Shusta; Michael L Shuler; Kelvin H Lee
Murine in vitro model of the blood-brain barrier for evaluating drug transport.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2011;42(1-2):148-55.
2010: Shin Ae Kim; Kyung Min Byun; Kyujung Kim; Seong Min Jang; Kyungjae Ma; Youngjin Oh; Donghyun Kim; Sung Guk Kim; Michael L Shuler; Sung Min Jang; Sung June Kim
Surface-enhanced localized surface plasmon resonance biosensing of avian influenza DNA hybridization using subwavelength metallic nanoarrays.
Nanotechnology 2010;21(35):355503.
2010: Jong Hwan Sung; Mandy B Esch; Michael L Shuler
Integration of in silico and in vitro platforms for pharmacokinetic-pharmacodynamic modeling.
Expert opinion on drug metabolism & toxicology 2010;6(9):1063-81.
2010: Mandy B Esch; Jong H Sung; Michael L Shuler
Promises, challenges and future directions of microCCAs.
Journal of biotechnology 2010;148(1):64-9.
2010: Patricia L Foley; David B Wilson; Michael L Shuler
Macromolecular crowding can account for RNase-sensitive constraint of bacterial nucleoid structure.
Biochemical and biophysical research communications 2010;395(1):42-7.
2010: Beum Jun Kim; David J Schneider; Samuel W Cartinhour; Michael L Shuler
Complex responses to culture conditions in Pseudomonas syringae pv. tomato DC3000 continuous cultures: the role of iron in cell growth and virulence factor induction.
Biotechnology and bioengineering 2010;105(5):955-64.
2010: Jong Hwan Sung; Carrie Kam; Michael L Shuler
A microfluidic device for a pharmacokinetic-pharmacodynamic (PK-PD) model on a chip.
Lab on a chip 2010;10(4):446-55.
2010: P L Foley; Michael L Shuler
Considerations for the design and construction of a synthetic platform cell for biotechnological applications.
Biotechnology and bioengineering 2010;105(1):26-36.
2010: Jong Hwan Sung; Michael L Shuler
In vitro microscale systems for systematic drug toxicity study.
Bioprocess and biosystems engineering 2010;33(1):5-19.
2009: Jong Hwan Sung; Jong-ryul Choi; Donghyun Kim; Michael L Shuler
Fluorescence optical detection in situ for real-time monitoring of cytochrome P450 enzymatic activity of liver cells in multiple microfluidic devices.
Biotechnology and bioengineering 2009;104(3):516-25.
2009: Gretchen J Mahler; Mandy B Esch; Raymond P Glahn; Michael L Shuler
Characterization of a gastrointestinal tract microscale cell culture analog used to predict drug toxicity.
Biotechnology and bioengineering 2009;104(1):193-205.
2009: Jong Hwan Sung; Michael L Shuler
Prevention of air bubble formation in a microfluidic perfusion cell culture system using a microscale bubble trap.
Biomedical microdevices 2009;11(4):731-8.
2009: Gretchen J Mahler; Michael L Shuler; Raymond P Glahn
Characterization of Caco-2 and HT29-MTX cocultures in an in vitro digestion/cell culture model used to predict iron bioavailability.
The Journal of nutritional biochemistry 2009;20(7):494-502.
2009: Jong Hwan Sung; Michael L Shuler
A micro cell culture analog (microCCA) with 3-D hydrogel culture of multiple cell lines to assess metabolism-dependent cytotoxicity of anti-cancer drugs.
Lab on a chip 2009;9(10):1385-94.
2009: Beum Jun Kim; Joon Ho Park; Tai Hyun Park; Philip A Bronstein; David J Schneider; Samuel Cartinhour; Michael L Shuler
Effect of iron concentration on the growth rate of Pseudomonas syringae and the expression of virulence factors in hrp-inducing minimal medium.
Applied and environmental microbiology 2009;75(9):2720-6.
2009: Daniel A Tatosian; Michael L Shuler
A novel system for evaluation of drug mixtures for potential efficacy in treating multidrug resistant cancers.
Biotechnology and bioengineering 2009;103(1):187-98.
2009: Jong Hwan Sung; Anjali Dhiman; Michael L Shuler
A combined pharmacokinetic-pharmacodynamic (PK-PD) model for tumor growth in the rat with UFT administration.
Journal of pharmaceutical sciences 2009;98(5):1885-904.
2009: Hui Xu; Michael L Shuler
Quantification of chemical-polymer surface interactions in microfluidic cell culture devices.
Biotechnology progress 2009;25(2):543-51.
2009: Iman A El Gheriany; Daniela Bocioaga; Anthony G Hay; William C Ghiorse; Michael L Shuler; Leonard W Lion
Iron requirement for Mn(II) oxidation by Leptothrix discophora SS-1.
Applied and environmental microbiology 2009;75(5):1229-35.
2009: Patricia L Echtenkamp; David B Wilson; Michael L Shuler
Cell cycle progression in Escherichia coli B/r affects transcription of certain genes: Implications for synthetic genome design.
Biotechnology and bioengineering 2009;102(3):902-9.
2008: Hui Xu; W Lee Kraus; Michael L Shuler
Development of a stable dual cell-line GFP expression system to study estrogenic endocrine disruptors.
Biotechnology and bioengineering 2008;101(6):1276-87.
2008: Jae-Young Kim; Anne Doody; David J Chen; Gina H Cremona; Michael L Shuler; David Putnam; Matthew P DeLisa
Engineered bacterial outer membrane vesicles with enhanced functionality.
Journal of molecular biology 2008;380(1):51-66.
2008: Gretchen J McAuliffe; Jung Yun Chang; Raymond P Glahn; Michael L Shuler
Development of a gastrointestinal tract microscale cell culture analog to predict drug transport.
Molecular & cellular biomechanics : MCB 2008;5(2):119-32.
2008: Shin Ae Kim; Kyung Min Byun; Jonghwan Lee; Jung Hoon Kim; Dong-Ghi Albert Kim; Hyoungwon Baac; Michael L Shuler; Sung June Kim
Optical measurement of neural activity using surface plasmon resonance.
Optics letters 2008;33(9):914-6.
2008: James P Camp; Tracy Stokol; Michael L Shuler
Fabrication of a multiple-diameter branched network of microvascular channels with semi-circular cross-sections using xenon difluoride etching.
Biomedical microdevices 2008;10(2):179-86.
2007: Alejandro Becerra-Arteaga; Michael L Shuler
Influence of culture medium supplementation of tobacco NT1 cell suspension cultures on the N-glycosylation of human secreted alkaline phosphatase.
Biotechnology and bioengineering 2007;97(6):1585-93.
2007: Evgeni V Nikolaev; Jordan C Atlas; Michael L Shuler
Sensitivity and control analysis of periodically forced reaction networks using the Green's function method.
Journal of theoretical biology 2007;247(3):442-61.
2007: Shing-Yi Cheng; Steven Heilman; Max Wasserman; Shivaun Archer; Michael L Shuler; Mingming Wu
A hydrogel-based microfluidic device for the studies of directed cell migration.
Lab on a chip 2007;7(6):763-9.
2007: Zhiqiang Hu; Jing Jin; Héctor D Abruña; Paul L Houston; Anthony G Hay; William C Ghiorse; Michael L Shuler; Gabriela Hidalgo; Leonard W Lion
Spatial distributions of copper in microbial biofilms by scanning electrochemical microscopy.
Environmental science & technology 2007;41(3):936-41.
2006: Alejandro Becerra-Arteaga; Hugh S Mason; Michael L Shuler
Production, secretion, and stability of human secreted alkaline phosphatase in tobacco NT1 cell suspension cultures.
Biotechnology progress 2006;22(6):1643-9.
2006: Beum Jun Kim; Donna M Gibson; Michael L Shuler
Effect of the plant peptide regulator, phytosulfokine-alpha, on the growth and Taxol production from Taxus sp. suspension cultures.
Biotechnology and bioengineering 2006;95(1):8-14.
2006: Hyoungwon Baac; Jozsef P Hajos; Jennifer Lee; Donghyun Kim; Sung June Kim; Michael L Shuler
Antibody-based surface plasmon resonance detection of intact viral pathogen.
Biotechnology and bioengineering 2006;94(4):815-9.
2006: Jinpian Diao; Lincoln Young; Sue Kim; Elizabeth A Fogarty; Steven M Heilman; Peng Zhou; Michael L Shuler; Mingming Wu; Matthew P DeLisa
A three-channel microfluidic device for generating static linear gradients and its application to the quantitative analysis of bacterial chemotaxis.
Lab on a chip 2006;6(3):381-8.
2005: Leslie E Patton; Michael L Shuler; Leonard W Lion
Behavior of lead in a model microbial predator-prey system.
Environmental toxicology and chemistry / SETAC 2005;24(11):2734-41.
2005: Daniel A Tatosian; Michael L Shuler; Donghyun Kim
Portable in situ fluorescence cytometry of microscale cell-based assays.
Optics letters 2005;30(13):1689-91.
2005: Zhiqiang Hu; Gabriela Hidalgo; Paul L Houston; Anthony G Hay; Michael L Shuler; Héctor D Abruña; William C Ghiorse; Leonard W Lion
Determination of spatial distributions of zinc and active biomass in microbial biofilms by two-photon laser scanning microscopy.
Applied and environmental microbiology 2005;71(7):4014-21.
2005: Beum Jun Kim; Donna M Gibson; Michael L Shuler
Relationship of viability and apoptosis to taxol production in Taxus sp. suspension cultures elicited with methyl jasmonate.
Biotechnology progress 2005;21(3):700-7.
2005: Sarina Harris Ma; Lori A Lepak; Rifat J Hussain; William Shain; Michael L Shuler
An endothelial and astrocyte co-culture model of the blood-brain barrier utilizing an ultra-thin, nanofabricated silicon nitride membrane.
Lab on a chip 2005;5(1):74-85.
2004: Beum Jun Kim; Donna M Gibson; Michael L Shuler
Effect of subculture and elicitation on instability of taxol production in Taxus sp. suspension cultures.
Biotechnology progress 2004;20(6):1666-73.
2004: Christoph E Joosten; Leonard S Cohen; Gerd Ritter; Carl A Batt; Michael L Shuler
Glycosylation profiles of the human colorectal cancer A33 antigen naturally expressed in the human colorectal cancer cell line SW1222 and expressed as recombinant protein in different insect cell lines.
Biotechnology progress 2004;20(4):1273-9.
2004: Kwanchanok Viravaidya; Edward Jan; Michael L Shuler
Lipid-gel and poly(dimethylsiloxane) film to mimic bioaccumulation in adipocytes.
Biotechnology and bioengineering 2004;86(6):643-9.
2004: Anna Jensen-Spaulding; Kristen Cabral; Michael L Shuler; Leonard W Lion
Predicting the rate and extent of cadmium and copper desorption from soils in the presence of bacterial extracellular polymer.
Water research 2004;38(9):2230-9.
2004: Kwanchanok Viravaidya; Michael L Shuler
Incorporation of 3T3-L1 cells to mimic bioaccumulation in a microscale cell culture analog device for toxicity studies.
Biotechnology progress 2004;20(2):590-7.
2004: Anna Jensen-Spaulding; Michael L Shuler; Leonard W Lion
Mobilization of adsorbed copper and lead from naturally aged soil by bacterial extracellular polymers.
Water research 2004;38(5):1121-8.
2004: Aaron Sin; Christopher F Reardon; Michael L Shuler
A self-priming microfluidic diaphragm pump capable of recirculation fabricated by combining soft lithography and traditional machining.
Biotechnology and bioengineering 2004;85(3):359-63.
2004: Leslie E Patton; Michael L Shuler; Leonard W Lion
Development of a model microbial predator-prey system suitable for studies of the behavior of toxic trace metals.
Environmental toxicology and chemistry / SETAC 2004;23(2):292-7.
2004: Aaron Sin; Katherine C Chin; Muhammad F Jamil; Yordan Kostov; Govind Rao; Michael L Shuler
The design and fabrication of three-chamber microscale cell culture analog devices with integrated dissolved oxygen sensors.
Biotechnology progress 2004;20(1):338-45.
2004: Kwanchanok Viravaidya; Aaron Sin; Michael L Shuler
Development of a microscale cell culture analog to probe naphthalene toxicity.
Biotechnology progress 2004;20(1):316-23.
2003: Christoph E Joosten; Tai Hyun Park; Michael L Shuler
Effect of silkworm hemolymph on N-linked glycosylation in two Trichoplusia ni insect cell lines.
Biotechnology and bioengineering 2003;83(6):695-705.
2003: Mark Smith; Liz Richter; Charles J Arntzen; Michael L Shuler; Hugh S Mason
Structural characterization of plant-derived hepatitis B surface antigen employed in oral immunization studies.
Vaccine 2003;21(25-26):4011-21.
2003: Susan C Roberts; Michael C Naill; Donna M Gibson; Michael L Shuler
A simple method for enhancing paclitaxel release from Taxus canadensis cell suspension cultures utilizing cell wall digesting enzymes.
Plant cell reports 2003;21(12):1217-20.
2003: Christoph E Joosten; Michael L Shuler
Effect of culture conditions on the degree of sialylation of a recombinant glycoprotein expressed in insect cells.
Biotechnology progress 2003;19(3):739-49.
2003: Tai Hyun Park; Michael L Shuler
Integration of cell culture and microfabrication technology.
Biotechnology progress 2003;19(2):243-53.
2003: Christoph E Joosten; Michael L Shuler
Production of a sialylated N-linked glycoprotein in insect cells: role of glycosidases and effect of harvest time on glycosylation.
Biotechnology progress 2003;19(1):193-201.
2003: Laura A Palomares; Christoph E Joosten; Patrick R Hughes; Robert R Granados; Michael L Shuler
Novel insect cell line capable of complex N-glycosylation and sialylation of recombinant proteins.
Biotechnology progress 2003;19(1):185-92.
2002: Mark Smith; Hugh S Mason; Michael L Shuler
Hepatitis B surface antigen (HBsAg) expression in plant cell culture: Kinetics of antigen accumulation in batch culture and its intracellular form.
Biotechnology and bioengineering 2002;80(7):812-22.
2002: Michelle C Brincat; Donna M Gibson; Michael L Shuler
Alterations in Taxol production in plant cell culture via manipulation of the phenylalanine ammonia lyase pathway.
Biotechnology progress 2002;18(6):1149-56.
2002: Carolyn W T Lee-Parsons; Michael L Shuler
The effect of ajmalicine spiking and resin addition timing on the production of indole alkaloids from Catharanthus roseus cell cultures.
Biotechnology and bioengineering 2002;79(4):408-15.
2002: Kwanchanok Viravaidya; Michael L Shuler
The effect of various substrates on cell attachment and differentiation of 3T3-F442A preadipocytes.
Biotechnology and bioengineering 2002;78(4):454-8.
2002: Mark Smith; Mark E Keegan; Hugh S Mason; Michael L Shuler
Factors important in the extraction, stability and in vitro assembly of the hepatitis B surface antigen derived from recombinant plant systems.
Biotechnology progress 2002;18(3):538-50.
2002: Kwanchanok Viravaidya; Michael L Shuler
Prediction of naphthalene bioaccumulation using an adipocyte cell line model.
Biotechnology progress 2002;18(2):174-81.
2002: Yarrow M Nelson; Leonard W Lion; Michael L Shuler; William C Ghiorse
Effect of oxide formation mechanisms on lead adsorption by biogenic manganese (hydr)oxides, iron (hydr)oxides, and their mixtures.
Environmental science & technology 2002;36(3):421-5.
2001: S T Browning; Michael L Shuler
Towards the development of a minimal cell model by generalization of a model of Escherichia coli: use of dimensionless rate parameters.
Biotechnology and bioengineering 2001;76(3):187-92.
2001: Lokesh Joshi; Michael L Shuler; HA Wood
Production of a sialylated N-linked glycoprotein in insect cells.
Biotechnology progress 2001;17(5):822-7.
2001: A R Wilson; Leonard W Lion; Y M Nelson; Michael L Shuler; William C Ghiorse
The effects of pH and surface composition on Pb adsorption to natural freshwater biofilms.
Environmental science & technology 2001;35(15):3182-9.
2001: R A Taticek; C Choi; S E Phan; L A Palomares; Michael L Shuler
Comparison of growth and recombinant protein expression in two different insect cell lines in attached and suspension culture.
Biotechnology progress 2001;17(4):676-84.
2001: A Liu; I S Ahn; C Mansfield; Leonard W Lion; Michael L Shuler; William C Ghiorse
Phenanthrene desorption from soil in the presence of bacterial extracellular polymer: observations and model predictions of dynamic behavior.
Water research 2001;35(3):835-43.
2000: Lokesh Joshi; T R Davis; T S Mattu; P M Rudd; R A Dwek; Michael L Shuler; HA Wood
Influence of baculovirus-host cell interactions on complex N-linked glycosylation of a recombinant human protein.
Biotechnology progress 2000;16(4):650-6.
2000: A Ghanem; Michael L Shuler
Characterization of a perfusion reactor utilizing mammalian cells on microcarrier beads.
Biotechnology progress 2000;16(3):471-9.
2000: B Dogan; Hugh S Mason; L Richter; Jean Hunter; Michael L Shuler
Process options in hepatitis B surface antigen extraction from transgenic potato.
Biotechnology progress 2000;16(3):435-41.
2000: A Ghanem; Michael L Shuler
Combining cell culture analogue reactor designs and PBPK models to probe mechanisms of naphthalene toxicity.
Biotechnology progress 2000;16(3):334-45.
1999: I S Ahn; William C Ghiorse; Leonard W Lion; Michael L Shuler
Independent prediction of naphthalene transport and biodegradation in soil with a mathematical model.
Biotechnology and bioengineering 1999;65(1):65-75.
1999: Raymond E B Ketchum; M Tandon; Donna M Gibson; T Begley; Michael L Shuler
Isolation of labeled 9-dihydrobaccatin III and related taxoids from cell cultures of taxuscell cultures of taxus canadensis elicited with m.
Journal of natural products 1999;62(10):1395-8.
1999: Michael L Shuler
Single-cell models: promise and limitations.
Journal of biotechnology 1999;71(1-3):225-8.
1999: M Donaldson; HA Wood; PC Kulakosky; Michael L Shuler
Glycosylation of a recombinant protein in the Tn5B1-4 insect cell line: influence of ammonia, time of harvest, temperature, and dissolved oxygen.
Biotechnology and bioengineering 1999;63(3):255-62.
1999: D J Quick; Michael L Shuler
Use of in vitro data for construction of a physiologically based pharmacokinetic model for naphthalene in rats and mice to probe species differences.
Biotechnology progress 1999;15(3):540-55.
1999: M Donaldson; HA Wood; PC Kulakosky; Michael L Shuler
Use of mannosamine for inducing the addition of outer arm N-acetylglucosamine onto N-linked oligosaccharides of recombinant proteins in insect cells.
Biotechnology progress 1999;15(2):168-73.
1999: Raymond E B Ketchum; Donna M Gibson; Rodney B Croteau; Michael L Shuler
The kinetics of taxoid accumulation in cell suspension cultures of Taxus following elicitation with methyl jasmonate.
Biotechnology and bioengineering 1999;62(1):97-105.
1998: I S Ahn; William C Ghiorse; Leonard W Lion; Michael L Shuler
Growth kinetics of Pseudomonas putida G7 on naphthalene and occurrence of naphthalene toxicity during nutrient deprivation.
Biotechnology and bioengineering 1998;59(5):587-94.
1998: M S Donaldson; Michael L Shuler
Low-cost serum-free medium for the BTI-Tn5B1-4 insect cell line.
Biotechnology progress 1998;14(4):573-9.
1998: M S Donaldson; Michael L Shuler
Effects of long-term passaging of BTI-Tn5B1-4 insect cells on growth and recombinant protein production.
Biotechnology progress 1998;14(4):543-7.
1998: N A Mufti; Michael L Shuler
Different In Vitro Systems Affect CYPIA1 Activity in Response to 2,3,7,8-Tetrachlorodibenzo-p-dioxin.
Toxicology in vitro : an international journal published in association with BIBRA 1998;12(3):259-72.
1998: PC Kulakosky; Michael L Shuler; HA Wood
N-glycosylation of a baculovirus-expressed recombinant glycoprotein in three insect cell lines.
In vitro cellular & developmental biology. Animal 1998;34(2):101-8.
1997: K U Dee; Michael L Shuler
A mathematical model of the trafficking of acid-dependent enveloped viruses: application to the binding, uptake, and nuclear accumulation of baculovirus.
Biotechnology and bioengineering 1997;54(5):468-90.
1997: K U Dee; HA Wood; Michael L Shuler
Inducing single-cell suspension of BTI-TN5B1-4 insect cells: II. The effect of sulfated polyanions on baculovirus infection.
Biotechnology and bioengineering 1997;54(3):206-20.
1997: K U Dee; Michael L Shuler; HA Wood
Inducing single-cell suspension of BTI-TN5B1-4 insect cells: I. The use of sulfated polyanions to prevent cell aggregation and enhance recombinant protein production.
Biotechnology and bioengineering 1997;54(3):191-205.
1997: R A Taticek; Michael L Shuler
Effect of elevated oxygen and glutamine levels on foreign protein production at high cell densities using the insect cell-baculovirus expression system.
Biotechnology and bioengineering 1997;54(2):142-52.
1997: K U Dee; Michael L Shuler
Optimization of an assay for baculovirus titer and design of regimens for the synchronous infection of insect cells.
Biotechnology progress 1997;13(1):14-24.
1996: N A Mufti; Michael L Shuler
Possible role of arachidonic acid in stress-induced cytochrome P450IA1 activity.
Biotechnology progress 1996;12(6):847-54.
1996: Michael L Shuler; A Ghanem; D Quick; M C Wong; P Miller
A self-regulating cell culture analog device to mimic animal and human toxicological responses.
Biotechnology and bioengineering 1996;52(1):45-60.
1996: L J Pestchanker; S C Roberts; Michael L Shuler
Kinetics of taxol production and nutrient use in suspension cultures of Taxus cuspidata in shake flasks and a Wilson-type bioreactor.
Enzyme and microbial technology 1996;19(4):256-60.
1996: I S Ahn; Leonard W Lion; Michael L Shuler
Microscale-based modeling of polynuclear aromatic hydrocarbon transport and biodegradation in soil.
Biotechnology and bioengineering 1996;51(1):1-14.
1996: V Srinivasan; V Ciddi; V Bringi; Michael L Shuler
Metabolic inhibitors, elicitors, and precursors as tools for probing yield limitation in taxane production by Taxus chinensis cell cultures.
Biotechnology progress 1996;12(4):457-65.
1996: L M Sweeney; Michael L Shuler; D J Quick; J G Babish
A preliminary physiologically based pharmacokinetic model for naphthalene and naphthalene oxide in mice and rats.
Annals of biomedical engineering 1996;24(2):305-20.
1995: N A Mufti; Michael L Shuler
Induction of cytochrome P-450IA1 activity in response to sublethal stresses in microcarrier-attached Hep G2 cells.
Biotechnology progress 1995;11(6):659-63.
1995: L M Sweeney; Michael L Shuler; John G Babish; A Ghanem
A cell culture analogue of rodent physiology: Application to naphthalene toxicology.
Toxicology in vitro : an international journal published in association with BIBRA 1995;9(3):307-16.
1995: N A Mufti; N A Bleckwenn; John G Babish; Michael L Shuler
Possible involvement of the Ah receptor in the induction of cytochrome P-450IA1 under conditions of hydrodynamic shear in microcarrier-attached hepatoma cell lines.
Biochemical and biophysical research communications 1995;208(1):144-52.
1995: T J Wickham; Michael L Shuler; Daniel A Hammer
A simple model to predict the effectiveness of molecules that block attachment of human rhinoviruses and other viruses.
Biotechnology progress 1995;11(2):164-70.
1995: J H Chen; D R Czajka; Leonard W Lion; Michael L Shuler; William C Ghiorse
Trace metal mobilization in soil by bacterial polymers.
Environmental health perspectives 1995;103 Suppl 1():53-8.
1995: T J Wickham; Glen R Nemerow; HA Wood; Michael L Shuler
Comparison of different cell lines for the production of recombinant baculovirus proteins.
Methods in molecular biology (Clifton, N.J.) 1995;39():385-95.
1994: Michael L Shuler
Bioreactor engineering as an enabling technology to tap biodiversity. The case of taxol.
Annals of the New York Academy of Sciences 1994;745():455-61.
1994: R A Taticek; C W Lee; Michael L Shuler
Large-scale insect and plant cell culture.
Current opinion in biotechnology 1994;5(2):165-74.
1993: I S Chung; R A Taticek; Michael L Shuler
Production of human alkaline phosphatase, a secreted, glycosylated protein, from a baculovirus expression system and the attachment-dependent cell line Trichoplusia ni BTI-Tn 5B1-4 using a split-flow, air-lift bioreactor.
Biotechnology progress 1993;9(6):675-8.
1993: P Wu; N G Ray; Michael L Shuler
A computer model for intracellular pH regulation in Chinese hamster ovary cells.
Biotechnology progress 1993;9(4):374-84.
1993: T R Davis; T J Wickham; K A McKenna; Robert R Granados; Michael L Shuler; HA Wood
Comparative recombinant protein production of eight insect cell lines.
In vitro cellular & developmental biology. Animal 1993;29A(5):388-90.
1993: A P Togna; Michael L Shuler; D B Wilson
Effects of plasmid copy number and runaway plasmid replication on overproduction and excretion of beta-lactamase from Escherichia coli.
Biotechnology progress 1993;9(1):31-9.
1992: T J Wickham; Michael L Shuler; Daniel A Hammer; Robert R Granados; HA Wood
Equilibrium and kinetic analysis of Autographa californica nuclear polyhedrosis virus attachment to different insect cell lines.
The Journal of general virology 1992;73 ( Pt 12)():3185-94.
1992: P Wu; N G Ray; Michael L Shuler
A single-cell model for CHO cells.
Annals of the New York Academy of Sciences 1992;665():152-87.
1992: T J Wickham; T Davis; Robert R Granados; Michael L Shuler; HA Wood
Screening of insect cell lines for the production of recombinant proteins and infectious virus in the baculovirus expression system.
Biotechnology progress 1992;8(5):391-6.
1992: J Fu; A P Togna; Michael L Shuler; D B Wilson
Escherichia coli host cell modifications in continuous culture affecting heterologous protein overproduction: a population dynamics study.
Biotechnology progress 1992;8(4):340-6.
1991: G A Murgel; Leonard W Lion; C Acheson; Michael L Shuler; D Emerson; William C Ghiorse
Experimental apparatus for selection of adherent microorganisms under stringent growth conditions.
Applied and environmental microbiology 1991;57(7):1987-96.
1990: T J Wickham; Robert R Granados; HA Wood; Daniel A Hammer; Michael L Shuler
General analysis of receptor-mediated viral attachment to cell surfaces.
Biophysical journal 1990;58(6):1501-16.
1990: Michael L Shuler; T Cho; T Wickham; O Ogonah; Marcel Kool; Daniel A Hammer; Robert R Granados; HA Wood
Bioreactor development for production of viral pesticides or heterologous proteins in insect cell cultures.
Annals of the New York Academy of Sciences 1990;589():399-422.
1990: J J Chalmers; E Kim; J N Telford; E Y Wong; W C Tacon; Michael L Shuler; D B Wilson
Effects of temperature on Escherichia coli overproducing beta-lactamase or human epidermal growth factor.
Applied and environmental microbiology 1990;56(1):104-11.
1987: B G Kim; T A Good; M M Ataai; Michael L Shuler
Growth behavior and prediction of copy number and retention of ColE1-type plasmids in E. coli under slow growth conditions.
Annals of the New York Academy of Sciences 1987;506():384-95.
1986: G Georgiou; J N Telford; Michael L Shuler; D B Wilson
Localization of inclusion bodies in Escherichia coli overproducing beta-lactamase or alkaline phosphatase.
Applied and environmental microbiology 1986;52(5):1157-61.
1986: M M Ataai; Michael L Shuler
Mathematical model for the control of ColE1 type plasmid replication.
Plasmid 1986;16(3):204-12.
1986: T Cho; Michael L Shuler
Multimembrane bioreactor for extractive fermentation.
Biotechnology progress 1986;2(1):53-60.
1985: K M Hsieh; Leonard W Lion; Michael L Shuler
Bioreactor for the study of defined interactions of toxic metals and biofilms.
Applied and environmental microbiology 1985;50(5):1155-61.