FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Gary Shull

Research Profile

Living Beings

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Patrick J Schultheis; Ellen Sidransky; Rafael J Tamargo; Taiji Tsunemi; Wendy Westbroek; Mark E Bardgett; Anil Kumar Chava; Yinhuai Chen; Amy K Clippinger; Dennis W Dickson; Osunde Ekhator; Sheila M Fleming; Matt Gannon; Benoit Giasson; Kristi L Haik; Elizabeth Hoffman; John Howard; Dimitri Krainc; Jada Lewis; Stephen C Linn; Joseph R Mazzulli; Vikram Prasad; Gary E Shull
Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.
Mingmin Chen; Jeppe Praetorius; Brigitte Riederer; Gary E Shull; Anurag Kumar Singh; Nicole Stieger; Jian Wang; Fang Xiao; Wen Zheng; Christian Aalkjaer; Ursula Seidler
The electroneutral Na⁺:HCO₃⁻ cotransporter NBCn1 is a major pHi regulator in murine duodenum.
Gary E Shull; Marian L Miller; Vikram Prasad
Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Gary Shull (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Patrick J Schultheis; Ellen Sidransky; Rafael J Tamargo; Taiji Tsunemi; Wendy Westbroek; Mark E Bardgett; Anil Kumar Chava; Yinhuai Chen; Amy K Clippinger; Dennis W Dickson; Osunde Ekhator; Sheila M Fleming; Matt Gannon; Benoit Giasson; Kristi L Haik; Elizabeth Hoffman; John Howard; Dimitri Krainc; Jada Lewis; Stephen C Linn; Joseph R Mazzulli; Vikram Prasad; Gary E Shull
Atp13a2-deficient mice exhibit neuronal ceroid lipofuscinosis, limited α-synuclein accumulation and age-dependent sensorimotor deficits.
Human molecular genetics 2013;22(10):2067-82.
2012: Mingmin Chen; Jeppe Praetorius; Brigitte Riederer; Gary E Shull; Anurag Kumar Singh; Nicole Stieger; Jian Wang; Fang Xiao; Wen Zheng; Christian Aalkjaer; Ursula Seidler
The electroneutral Na⁺:HCO₃⁻ cotransporter NBCn1 is a major pHi regulator in murine duodenum.
The Journal of physiology 2012;590(Pt 14):3317-33.
2011: Gary E Shull; Marian L Miller; Vikram Prasad
Secretory pathway stress responses as possible mechanisms of disease involving Golgi Ca2+ pump dysfunction.
BioFactors (Oxford, England) 2011;37(3):150-8.
2011: Marian L Miller; Anastasia Andringa; Patrick J Schultheis; Gary E Shull
Loss of the NHE2 Na+/H+ exchanger in mice results in dilation of folliculo-stellate cell canaliculi.
Journal of biomedicine & biotechnology 2011;2011():510827.
2011: Nabeel J Al Moamen; Vikram Prasad; Ilona Bodi; Marian L Miller; Michelle L Neiman; Valerie M Lasko; Seth L Alper; David F Wieczorek; John N Lorenz; Gary E Shull
Loss of the AE3 anion exchanger in a hypertrophic cardiomyopathy model causes rapid decompensation and heart failure.
Journal of molecular and cellular cardiology 2011;50(1):137-46.
2010: Emily M Bradford; Marian L Miller; Vikram Prasad; Michelle L Nieman; Lara R Gawenis; Mark Berryman; John N Lorenz; Patrick Tso; Gary E Shull
CLIC5 mutant mice are resistant to diet-induced obesity and exhibit gastric hemorrhaging and increased susceptibility to torpor.
American journal of physiology. Regulatory, integrative and comparative physiology 2010;298(6):R1531-42.
2010: Marian L Miller; Anastasia Andringa; Yana Zavros; Emily M Bradford; Gary E Shull
Volume density, distribution, and ultrastructure of secretory and basolateral membranes and mitochondria predict parietal cell secretory (dys)function.
Journal of biomedicine & biotechnology 2010;2010():394198.
2010: Xinzhi Chen; Douglas B Kintner; Akemichi Baba; Toshio Matsuda; Gary E Shull; Dandan Sun
Protein aggregation in neurons following OGD: a role for Na+ and Ca2+ ionic dysregulation.
Journal of neurochemistry 2010;112(1):173-82.
2009: Haoyang Yu; Brigitte Riederer; Nicole Stieger; Walter F Boron; Gary E Shull; Michael P Manns; Ursula E Seidler; Oliver Bachmann
Secretagogue stimulation enhances NBCe1 (electrogenic Na(+)/HCO(3)(-) cotransporter) surface expression in murine colonic crypts.
American journal of physiology. Gastrointestinal and liver physiology 2009;297(6):G1223-31.
2009: Emily M Bradford; Maureen Sartor; Lara R Gawenis; Lane L Clarke; Gary E Shull
Reduced NHE3-mediated Na+ absorption increases survival and decreases the incidence of intestinal obstructions in cystic fibrosis mice.
American journal of physiology. Gastrointestinal and liver physiology 2009;296(4):G886-98.
2008: Vikram Prasad; Ilona Bodi; Jamie W Meyer; Yigang Wang; Muhammad Ashraf; Sandra J Engle; Thomas Doetschman; Karena Sisco; Michelle L Nieman; Marian L Miller; John N Lorenz; Gary E Shull
Impaired cardiac contractility in mice lacking both the AE3 Cl-/HCO3- exchanger and the NKCC1 Na+-K+-2Cl- cotransporter: effects on Ca2+ handling and protein phosphatases.
The Journal of biological chemistry 2008;283(46):31303-14.
2008: Jing Luo; Yanping Wang; Hai Chen; Douglas B Kintner; Sam W Cramer; Josiah K Gerdts; Xinzhi Chen; Gary E Shull; Kenneth D Philipson; Dandan Sun
A concerted role of Na+ -K+ -Cl- cotransporter and Na+/Ca2+ exchanger in ischemic damage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(4):737-46.
2007: Rodney Diaz; Ana E Vazquez; Hongwei Dou; Dongguang Wei; Emma Lou Cardell; Jerry B Lingrel; Gary E Shull; Karen Jo Doyle; Ebenezer N Yamoah
Conservation of hearing by simultaneous mutation of Na,K-ATPase and NKCC1.
Journal of the Association for Research in Otolaryngology : JARO 2007;8(4):422-34.
2007: Jing Luo; Douglas B Kintner; Gary E Shull; Dandan Sun
ERK1/2-p90RSK-mediated phosphorylation of Na+/H+ exchanger isoform 1. A role in ischemic neuronal death.
The Journal of biological chemistry 2007;282(38):28274-84.
2007: Gbolahan Okunade; Marian L Miller; Mohamad Azhar; Anastasia Andringa; L Philip Sanford; Thomas Doetschman; Vikram Prasad; Gary E Shull
Loss of the Atp2c1 secretory pathway Ca(2+)-ATPase (SPCA1) in mice causes Golgi stress, apoptosis, and midgestational death in homozygous embryos and squamous cell tumors in adult heterozygotes.
The Journal of biological chemistry 2007;282(36):26517-27.
2007: Janet E Simpson; Clifford W Schweinfest; Gary E Shull; Lara R Gawenis; Nancy M Walker; Kathryn T Boyle; Manoocher Soleimani; Lane L Clarke
PAT-1 (Slc26a6) is the predominant apical membrane Cl-/HCO3- exchanger in the upper villous epithelium of the murine duodenum.
American journal of physiology. Gastrointestinal and liver physiology 2007;292(4):G1079-88.
2007: Lara R Gawenis; Emily M Bradford; Vikram Prasad; John N Lorenz; Janet E Simpson; Lane L Clarke; Alison L Woo; Christina Grisham; L Philip Sanford; Thomas Doetschman; Marian L Miller; Gary E Shull
Colonic anion secretory defects and metabolic acidosis in mice lacking the NBC1 Na+/HCO3- cotransporter.
The Journal of biological chemistry 2007;282(12):9042-52.
2007: Jing Luo; Yanping Wang; Xinzhi Chen; Hai Chen; Douglas B Kintner; Gary E Shull; Kenneth D Philipson; Dandan Sun
Increased tolerance to ischemic neuronal damage by knockdown of Na+-Ca2+ exchanger isoform 1.
Annals of the New York Academy of Sciences 2007;1099():292-305.
2007: Vikram Prasad; Gbolahan Okunade; Li Liu; Richard J Paul; Gary E Shull
Distinct phenotypes among plasma membrane Ca2+-ATPase knockout mice.
Annals of the New York Academy of Sciences 2007;1099():276-86.
2007: Douglas B Kintner; Jing Luo; Josiah Gerdts; Andy J Ballard; Gary E Shull; Dandan Sun
Role of Na+-K+-Cl- cotransport and Na+/Ca2+ exchange in mitochondrial dysfunction in astrocytes following in vitro ischemia.
American journal of physiology. Cell physiology 2007;292(3):C1113-22.
2007: Li Liu; Yukisato Ishida; Gbolahan Okunade; Gail J Pyne-Geithman; Gary E Shull; Richard J Paul
Distinct roles of PMCA isoforms in Ca2+ homeostasis of bladder smooth muscle: evidence from PMCA gene-ablated mice.
American journal of physiology. Cell physiology 2007;292(1):C423-31.
2006: John N Lorenz; Iva Dostanic-Larson; Gary E Shull; Jerry B Lingrel
Ouabain inhibits tubuloglomerular feedback in mutant mice with ouabain-sensitive alpha1 Na,K-ATPase.
Journal of the American Society of Nephrology : JASN 2006;17(9):2457-63.
2006: Li Liu; Yukisato Ishida; Gbolahan Okunade; Gary E Shull; Richard J Paul
Role of plasma membrane Ca2+-ATPase in contraction-relaxation processes of the bladder: evidence from PMCA gene-ablated mice.
American journal of physiology. Cell physiology 2006;290(4):C1239-47.
2006: Susan M Wall; Mark A Knepper; Kathryn A Hassell; Michael P Fischer; Adetola Shodeinde; Wonkyong Shin; Truyen Derek Pham; Jamie W Meyer; John N Lorenz; William H Beierwaltes; John R Dietz; Gary E Shull; Young-Hee Kim
Hypotension in NKCC1 null mice: role of the kidneys.
American journal of physiology. Renal physiology 2006;290(2):F409-16.
2006: Jing Luo; Hai Chen; Douglas B Kintner; Gary E Shull; Dandan Sun
Inhibition of Na+/H+ exchanger isoform 1 attenuates mitochondrial cytochrome C release in cortical neurons following in vitro ischemia.
Acta neurochirurgica. Supplement 2006;96():244-8.
2005: Jing Luo; Hai Chen; Douglas B Kintner; Gary E Shull; Dandan Sun
Decreased neuronal death in Na+/H+ exchanger isoform 1-null mice after in vitro and in vivo ischemia.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(49):11256-68.
2005: Deborah L Hunt; Bryan King; Dianna M Kahn; Ebenezer N Yamoah; Gary E Shull; Leah Krubitzer
Aberrant retinal projections in congenitally deaf mice: how are phenotypic characteristics specified in development and evolution?
The anatomical record. Part A, Discoveries in molecular, cellular, and evolutionary biology 2005;287(1):1051-66.
2005: Vikram Prasad; Gregory P Boivin; Marian L Miller; Lynne H Liu; Christopher R Erwin; Brad W Warner; Gary E Shull
Haploinsufficiency of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump, predisposes mice to squamous cell tumors via a novel mode of cancer susceptibility.
Cancer research 2005;65(19):8655-61.
2005: Douglas B Kintner; Andy Look; Gary E Shull; Dandan Sun
Stimulation of astrocyte Na+/H+ exchange activity in response to in vitro ischemia depends in part on activation of ERK1/2.
American journal of physiology. Cell physiology 2005;289(4):C934-45.
2005: Louise M Judd; Anastasia Andringa; Carlos A Rubio; Zachary Spicer; Gary E Shull; Marian L Miller
Gastric achlorhydria in H/K-ATPase-deficient (Atp4a(-/-)) mice causes severe hyperplasia, mucocystic metaplasia and upregulation of growth factors.
Journal of gastroenterology and hepatology 2005;20(8):1266-78.
2005: Jie Xu; Johanna Henriksnäs; Sharon Barone; David Witte; Gary E Shull; John G Forte; Lena Holm; Manoocher Soleimani
SLC26A9 is expressed in gastric surface epithelial cells, mediates Cl-/HCO3- exchange, and is inhibited by NH4+.
American journal of physiology. Cell physiology 2005;289(2):C493-505.
2005: Lara R Gawenis; Jeannette M Greeb; Vikram Prasad; Christina Grisham; L Philip Sanford; Thomas Doetschman; Anastasia Andringa; Marian L Miller; Gary E Shull
Impaired gastric acid secretion in mice with a targeted disruption of the NHE4 Na+/H+ exchanger.
The Journal of biological chemistry 2005;280(13):12781-9.
2005: William T Noonan; Alison L Woo; Michelle L Nieman; Vikram Prasad; Patrick J Schultheis; Gary E Shull; John N Lorenz
Blood pressure maintenance in NHE3-deficient mice with transgenic expression of NHE3 in small intestine.
American journal of physiology. Regulatory, integrative and comparative physiology 2005;288(3):R685-91.
2005: Yanfang Xu; Zhao Zhang; Valeriy Timofeyev; Dipika Sharma; Danyan Xu; Dipika Tuteja; Pei Hong Dong; Gias Ahmmed; Yong Ji; Gary E Shull; Muthu Periasamy; Nipavan Chiamvimonvat
The effects of intracellular Ca2+ on cardiac K+ channel expression and activity: novel insights from genetically altered mice.
The Journal of physiology 2005;562(Pt 3):745-58.
2005: Hai Chen; Jing Luo; Douglas B Kintner; Gary E Shull; Dandan Sun
Na(+)-dependent chloride transporter (NKCC1)-null mice exhibit less gray and white matter damage after focal cerebral ischemia.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2005;25(1):54-66.
2004: Matthew A Bailey; Gerhard Giebisch; Thecla Abbiati; Peter S Aronson; Lara R Gawenis; Gary E Shull; Tong Wang
NHE2-mediated bicarbonate reabsorption in the distal tubule of NHE3 null mice.
The Journal of physiology 2004;561(Pt 3):765-75.
2004: Lara R Gawenis; Hans Hut; Alice G M Bot; Gary E Shull; Hugo R de Jonge; Xavier Stien; Marian L Miller; Lane L Clarke
Electroneutral sodium absorption and electrogenic anion secretion across murine small intestine are regulated in parallel.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(6):G1140-9.
2004: Brett Lenart; Douglas B Kintner; Gary E Shull; Dandan Sun
Na-K-Cl cotransporter-mediated intracellular Na+ accumulation affects Ca2+ signaling in astrocytes in an in vitro ischemic model.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(43):9585-97.
2004: Patrick J Schultheis; Tamara T Hagen; Kate K O'Toole; Akiko Tachibana; Charles R Burke; Diana L McGill; Gbolahan Okunade; Gary E Shull
Characterization of the P5 subfamily of P-type transport ATPases in mice.
Biochemical and biophysical research communications 2004;323(3):731-8.
2004: Vikram Prasad; Gbolahan Okunade; Marian L Miller; Gary E Shull
Phenotypes of SERCA and PMCA knockout mice.
Biochemical and biophysical research communications 2004;322(4):1192-203.
2004: Gbolahan Okunade; Marian L Miller; Gail J Pyne; Roy L Sutliff; Kyle T O'Connor; Jonathan C Neumann; Anastasia Andringa; Daniel A Miller; Vikram Prasad; Thomas Doetschman; Richard J Paul; Gary E Shull
Targeted ablation of plasma membrane Ca2+-ATPase (PMCA) 1 and 4 indicates a major housekeeping function for PMCA1 and a critical role in hyperactivated sperm motility and male fertility for PMCA4.
The Journal of biological chemistry 2004;279(32):33742-50.
2004: Lara R Gawenis; Clara Ledoussal; Louise M Judd; Vikram Prasad; Seth L Alper; Alan Stuart-Tilley; Alison L Woo; Christina Grisham; L Philip Sanford; Thomas Doetschman; Marian L Miller; Gary E Shull
Mice with a targeted disruption of the AE2 Cl-/HCO3- exchanger are achlorhydric.
The Journal of biological chemistry 2004;279(29):30531-9.
2004: Douglas B Kintner; Gui Su; Brett Lenart; Andy J Ballard; Jamie W Meyer; Leong L Ng; Gary E Shull; Dandan Sun
Increased tolerance to oxygen and glucose deprivation in astrocytes from Na(+)/H(+) exchanger isoform 1 null mice.
American journal of physiology. Cell physiology 2004;287(1):C12-21.
2004: Oliver Bachmann; Brigitte Riederer; Heidi Rossmann; Stephanie Groos; P J Schultheis; Gary E Shull; Michael Gregor; Michael P Manns; Ursula Seidler
The Na+/H+ exchanger isoform 2 is the predominant NHE isoform in murine colonic crypts and its lack causes NHE3 upregulation.
American journal of physiology. Gastrointestinal and liver physiology 2004;287(1):G125-33.
2004: Jie Chen; Paul A McLean; Benjamin G Neel; Gbolahan Okunade; Gary E Shull; Henry H Wortis
CD22 attenuates calcium signaling by potentiating plasma membrane calcium-ATPase activity.
Nature immunology 2004;5(6):651-7.
2004: Lane L Clarke; Lara R Gawenis; Emily M Bradford; Louise M Judd; Kathryn T Boyle; Janet E Simpson; Gary E Shull; Hiroki Tanabe; Andre J Ouellette; Craig L Franklin; Nancy M Walker
Abnormal Paneth cell granule dissolution and compromised resistance to bacterial colonization in the intestine of CF mice.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(6):G1050-8.
2004: Jo El J Schultz; Betty J Glascock; Sandra A Witt; Michelle L Nieman; Kalpana J Nattamai; Lynne H Liu; John N Lorenz; Gary E Shull; Thomas R Kimball; Muthu Periasamy
Accelerated onset of heart failure in mice during pressure overload with chronically decreased SERCA2 calcium pump activity.
American journal of physiology. Heart and circulatory physiology 2004;286(3):H1146-53.
2003: Hassane Amlal; Clara Ledoussal; Sulaiman Sheriff; Gary E Shull; Manoocher Soleimani
Downregulation of renal AQP2 water channel and NKCC2 in mice lacking the apical Na+-H+ exchanger NHE3.
The Journal of physiology 2003;553(Pt 2):511-22.
2003: Jie Xu; Sharon Barone; Snezana Petrovic; Zhaohui Wang; Ursula Seidler; Brigitte Riederer; Krishnamurthy Ramaswamy; Pradeep K Dudeja; Gary E Shull; Manoocher Soleimani
Identification of an apical Cl-/HCO3- exchanger in gastric surface mucous and duodenal villus cells.
American journal of physiology. Gastrointestinal and liver physiology 2003;285(6):G1225-34.
2003: Yigang Wang; Jamie W Meyer; Muhammad Ashraf; Gary E Shull
Mice with a null mutation in the NHE1 Na+-H+ exchanger are resistant to cardiac ischemia-reperfusion injury.
Circulation research 2003;93(8):776-82.
2003: Alison L Woo; William T Noonan; Patrick J Schultheis; Jonathan C Neumann; Patrice A Manning; John N Lorenz; Gary E Shull
Renal function in NHE3-deficient mice with transgenic rescue of small intestinal absorptive defect.
American journal of physiology. Renal physiology 2003;284(6):F1190-8.
2003: Gary E Shull; Gbolahan Okunade; Lynne H Liu; Peter J Kozel; Muthu Periasamy; John N Lorenz; Vikram Prasad
Physiological functions of plasma membrane and intracellular Ca2+ pumps revealed by analysis of null mutants.
Annals of the New York Academy of Sciences 2003;986():453-60.
2002: Alison L Woo; Lucy A Gildea; Leslie M Tack; Marian L Miller; Zachary Spicer; David E Millhorn; Fred D Finkelman; Daniel J Hassett; Gary E Shull
In vivo evidence for interferon-gamma-mediated homeostatic mechanisms in small intestine of the NHE3 Na+/H+ exchanger knockout model of congenital diarrhea.
The Journal of biological chemistry 2002;277(50):49036-46.
2002: Jamie W Meyer; Michael Flagella; Roy L Sutliff; John N Lorenz; Michelle L Nieman; Craig S Weber; Richard J Paul; Gary E Shull
Decreased blood pressure and vascular smooth muscle tone in mice lacking basolateral Na(+)-K(+)-2Cl(-) cotransporter.
American journal of physiology. Heart and circulatory physiology 2002;283(5):H1846-55.
2002: Snezana Petrovic; Zhaohui Wang; Liyun Ma; Ursula Seidler; John G Forte; Gary E Shull; Manoocher Soleimani
Colocalization of the apical Cl-/HCO3- exchanger PAT1 and gastric H-K-ATPase in stomach parietal cells.
American journal of physiology. Gastrointestinal and liver physiology 2002;283(5):G1207-16.
2002: Ming Lu; Tong Wang; Qingshang Yan; Xinbo Yang; Ke Dong; Mark A Knepper; WenHui Wang; Gerhard Giebisch; Gary E Shull; Steven C Hebert
Absence of small conductance K+ channel (SK) activity in apical membranes of thick ascending limb and cortical collecting duct in ROMK (Bartter's) knockout mice.
The Journal of biological chemistry 2002;277(40):37881-7.
2002: John N Lorenz; Nancy R Baird; Louise M Judd; William T Noonan; Anastasia Andringa; Thomas Doetschman; Patrice A Manning; Lynne H Liu; Marian L Miller; Gary E Shull
Impaired renal NaCl absorption in mice lacking the ROMK potassium channel, a model for type II Bartter's syndrome.
The Journal of biological chemistry 2002;277(40):37871-80.
2002: Marian L Miller; Louise M Judd; Ian R van Driel; Anastasia Andringa; Michael Flagella; Sheila M Bell; Patrick J Schultheis; Zachary Spicer; Gary E Shull
The unique ultrastructure of secretory membranes in gastric parietal cells depends upon the presence of H+, K+ -ATPase.
Cell and tissue research 2002;309(3):369-80.
2002: Nancy M Walker; Michael Flagella; Lara R Gawenis; Gary E Shull; Lane L Clarke
An alternate pathway of cAMP-stimulated Cl secretion across the NKCC1-null murine duodenum.
Gastroenterology 2002;123(2):531-41.
2002: Keith Nehrke; Jorge Arreola; Ha-Van Nguyen; Jodi Pilato; Linda Richardson; Gbolahan Okunade; Raymond Baggs; Gary E Shull; James E Melvin
Loss of hyperpolarization-activated Cl(-) current in salivary acinar cells from Clcn2 knockout mice.
The Journal of biological chemistry 2002;277(26):23604-11.
2002: Jonathan Shillingford; Keiko Miyoshi; Michael Flagella; Gary E Shull; Lothar Hennighausen
Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis.
Molecular endocrinology (Baltimore, Md.) 2002;16(6):1309-21.
2002: Lara R Gawenis; Xavier Stien; Gary E Shull; Patrick J Schultheis; Alison L Woo; Nancy M Walker; Lane L Clarke
Intestinal NaCl transport in NHE2 and NHE3 knockout mice.
American journal of physiology. Gastrointestinal and liver physiology 2002;282(5):G776-84.
2002: Gui Su; Douglas B Kintner; Michael Flagella; Gary E Shull; Dandan Sun
Astrocytes from Na(+)-K(+)-Cl(-) cotransporter-null mice exhibit absence of swelling and decrease in EAA release.
American journal of physiology. Cell physiology 2002;282(5):C1147-60.
2002: Peter J Kozel; Rickie R Davis; Edward F Krieg; Gary E Shull; Lawrence C Erway
Deficiency in plasma membrane calcium ATPase isoform 2 increases susceptibility to noise-induced hearing loss in mice.
Hearing research 2002;164(1-2):231-9.
2002: Richard J Paul; Gary E Shull; Evangelia G Kranias
The sarcoplasmic reticulum and smooth muscle function: evidence from transgenic mice.
Novartis Foundation symposium 2002;246():228-38; discussion 238-43, 272-6.
2002: Snezana Petrovic; Zachary Spicer; Tracey Greeley; Gary E Shull; Manoocher Soleimani
Novel Schering and ouabain-insensitive potassium-dependent proton secretion in the mouse cortical collecting duct.
American journal of physiology. Renal physiology 2002;282(1):F133-43.
2001: Clara Ledoussal; Alison L Woo; Marian L Miller; Gary E Shull
Loss of the NHE2 Na(+)/H(+) exchanger has no apparent effect on diarrheal state of NHE3-deficient mice.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(6):G1385-96.
2001: Zachary Spicer; Lane L Clarke; Lara R Gawenis; Gary E Shull
Colonic H(+)-K(+)-ATPase in K(+) conservation and electrogenic Na(+) absorption during Na(+) restriction.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(6):G1369-77.
2001: Clara Ledoussal; John N Lorenz; Michelle L Nieman; Manoocher Soleimani; Patrick J Schultheis; Gary E Shull
Renal salt wasting in mice lacking NHE3 Na+/H+ exchanger but not in mice lacking NHE2.
American journal of physiology. Renal physiology 2001;281(4):F718-27.
2001: Heidi Rossmann; Oliver Bachmann; Z Wang; Gary E Shull; B Obermaier; Alan K Stuart-Tilley; Seth L Alper; Ursula Seidler
Differential expression and regulation of AE2 anion exchanger subtypes in rabbit parietal and mucous cells.
The Journal of physiology 2001;534(Pt 3):837-48.
2001: Tong Wang; Chao-Ling Yang; Thecla Abbiati; Gary E Shull; Gerhard Giebisch; Peter S Aronson
Essential role of NHE3 in facilitating formate-dependent NaCl absorption in the proximal tubule.
American journal of physiology. Renal physiology 2001;281(2):F288-92.
2001: Lynne H Liu; Gregory P Boivin; Vikram Prasad; Muthu Periasamy; Gary E Shull
Squamous cell tumors in mice heterozygous for a null allele of Atp2a2, encoding the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 Ca2+ pump.
The Journal of biological chemistry 2001;276(29):26737-40.
2001: Keerang Park; RL Evans; GE Watson; Keith Nehrke; Linda Richardson; Sheila M Bell; Patrick J Schultheis; A R Hand; Gary E Shull; James E Melvin
Defective fluid secretion and NaCl absorption in the parotid glands of Na+/H+ exchanger-deficient mice.
The Journal of biological chemistry 2001;276(29):27042-50.
2001: Albert Mennone; Daniel Biemesderfer; D Negoianu; Chao-Ling Yang; Thecla Abbiati; Patrick J Schultheis; Gary E Shull; Peter S Aronson; James L Boyer
Role of sodium/hydrogen exchanger isoform NHE3 in fluid secretion and absorption in mouse and rat cholangiocytes.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(2):G247-54.
2001: Heddwen L Brooks; A M Sorensen; James M Terris; Patrick J Schultheis; John N Lorenz; Gary E Shull; Mark A Knepper
Profiling of renal tubule Na+ transporter abundances in NHE3 and NCC null mice using targeted proteomics.
The Journal of physiology 2001;530(Pt 3):359-66.
2000: James E Melvin; Ha-Van Nguyen; RL Evans; Gary E Shull
What can transgenic and gene-targeted mouse models teach us about salivary gland physiology?
Advances in dental research 2000;14():5-11.
2000: Yong Ji; M Jane Lalli; Gopal J Babu; Y Xu; DL Kirkpatrick; Lynne H Liu; Nipavan Chiamvimonvat; Richard A Walsh; Gary E Shull; Muthu Periasamy
Disruption of a single copy of the SERCA2 gene results in altered Ca2+ homeostasis and cardiomyocyte function.
The Journal of biological chemistry 2000;275(48):38073-80.
2000: Gregory P Boivin; Patrick J Schultheis; Gary E Shull; Grant N Stemmermann
Variant form of diffuse corporal gastritis in NHE2 knockout mice.
Comparative medicine 2000;50(5):511-5.
2000: RL Evans; Keerang Park; R J Turner; GE Watson; Ha-Van Nguyen; M R Dennett; A R Hand; M Flagella; Gary E Shull; James E Melvin
Severe impairment of salivation in Na+/K+/2Cl- cotransporter (NKCC1)-deficient mice.
The Journal of biological chemistry 2000;275(35):26720-6.
2000: Zachary Spicer; Marian L Miller; Anastasia Andringa; Tara M Riddle; JJ Duffy; Thomas Doetschman; Gary E Shull
Stomachs of mice lacking the gastric H,K-ATPase alpha -subunit have achlorhydria, abnormal parietal cells, and ciliated metaplasia.
The Journal of biological chemistry 2000;275(28):21555-65.
2000: V J Wheat; H Shumaker; Charles E Burnham; Gary E Shull; James R Yankaskas; Manoocher Soleimani
CFTR induces the expression of DRA along with Cl(-)/HCO(3)(-) exchange activity in tracheal epithelial cells.
American journal of physiology. Cell physiology 2000;279(1):C62-71.
2000: Ha-Van Nguyen; Gary E Shull; James E Melvin
Muscarinic receptor-induced acidification in sublingual mucous acinar cells: loss of pH recovery in Na+-H+ exchanger-1 deficient mice.
The Journal of physiology 2000;523 Pt 1():139-46.
2000: Gary E Shull; Marian L Miller; Patrick J Schultheis
Lessons from genetically engineered animal models VIII. Absorption and secretion of ions in the gastrointestinal tract.
American journal of physiology. Gastrointestinal and liver physiology 2000;278(2):G185-90.
1999: RL Evans; Sheila M Bell; Patrick J Schultheis; Gary E Shull; James E Melvin
Targeted disruption of the Nhe1 gene prevents muscarinic agonist-induced up-regulation of Na(+)/H(+) exchange in mouse parotid acinar cells.
The Journal of biological chemistry 1999;274(41):29025-30.
1999: Michael Flagella; Lane L Clarke; Marian L Miller; Lawrence C Erway; Ralph A Giannella; Anastasia Andringa; Lara R Gawenis; J Kramer; JJ Duffy; Thomas Doetschman; John N Lorenz; Ebenezer N Yamoah; Emma Lou Cardell; Gary E Shull
Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf.
The Journal of biological chemistry 1999;274(38):26946-55.
1999: John N Lorenz; Patrick J Schultheis; Tim R Traynor; Gary E Shull; Jurgen Schnermann
Micropuncture analysis of single-nephron function in NHE3-deficient mice.
The American journal of physiology 1999;277(3 Pt 2):F447-53.
1999: James E Melvin; Keerang Park; Linda Richardson; Patrick J Schultheis; Gary E Shull
Mouse down-regulated in adenoma (DRA) is an intestinal Cl(-)/HCO(3)(-) exchanger and is up-regulated in colon of mice lacking the NHE3 Na(+)/H(+) exchanger.
The Journal of biological chemistry 1999;274(32):22855-61.
1999: Tong Wang; Chao-Ling Yang; Thecla Abbiati; Patrick J Schultheis; Gary E Shull; Gerhard Giebisch; Peter S Aronson
Mechanism of proximal tubule bicarbonate absorption in NHE3 null mice.
The American journal of physiology 1999;277(2 Pt 2):F298-302.
1999: J Kao; CN Fortner; L H Liu; Gary E Shull; Richard J Paul
Ablation of the SERCA3 gene alters epithelium-dependent relaxation in mouse tracheal smooth muscle.
The American journal of physiology 1999;277(2 Pt 1):L264-70.
1999: S Nakamura; Hassane Amlal; Patrick J Schultheis; JH Galla; Gary E Shull; Manoocher Soleimani
HCO-3 reabsorption in renal collecting duct of NHE-3-deficient mouse: a compensatory response.
The American journal of physiology 1999;276(6 Pt 2):F914-21.
1999: Sheila M Bell; Claire M Schreiner; Patrick J Schultheis; Marian L Miller; RL Evans; CV Vorhees; Gary E Shull; William J Scott
Targeted disruption of the murine Nhe1 locus induces ataxia, growth retardation, and seizures.
The American journal of physiology 1999;276(4 Pt 1):C788-95.
1999: Nancy R Baird; John Orlowski; E Z Szabó; H C Zaun; Patrick J Schultheis; Anil G Menon; Gary E Shull
Molecular cloning, genomic organization, and functional expression of Na+/H+ exchanger isoform 5 (NHE5) from human brain.
The Journal of biological chemistry 1999;274(7):4377-82.
1999: Muthu Periasamy; Thomas D Reed; Lynne H Liu; Yong Ji; EV Loukianov; Richard J Paul; Michelle L Nieman; Tara M Riddle; JJ Duffy; Thomas Doetschman; John N Lorenz; Gary E Shull
Impaired cardiac performance in heterozygous mice with a null mutation in the sarco(endo)plasmic reticulum Ca2+-ATPase isoform 2 (SERCA2) gene.
The Journal of biological chemistry 1999;274(4):2556-62.
1998: Patrick J Schultheis; John N Lorenz; Pierre Meneton; Michelle L Nieman; Tara M Riddle; Michael Flagella; JJ Duffy; Thomas Doetschman; Marian L Miller; Gary E Shull
Phenotype resembling Gitelman's syndrome in mice lacking the apical Na+-Cl- cotransporter of the distal convoluted tubule.
The Journal of biological chemistry 1998;273(44):29150-5.
1998: EV Loukianov; Yong Ji; DL Baker; T Reed; J Babu; T Loukianova; A Greene; Gary E Shull; Muthu Periasamy
Sarco(endo)plasmic reticulum Ca2+ ATPase isoforms and their role in muscle physiology and pathology.
Annals of the New York Academy of Sciences 1998;853():251-9.
1998: Peter J Kozel; R A Friedman; Lawrence C Erway; Ebenezer N Yamoah; Lynne H Liu; Tara M Riddle; JJ Duffy; Thomas Doetschman; Marian L Miller; Emma Lou Cardell; Gary E Shull
Balance and hearing deficits in mice with a null mutation in the gene encoding plasma membrane Ca2+-ATPase isoform 2.
The Journal of biological chemistry 1998;273(30):18693-6.
1998: Patrick J Schultheis; Lane L Clarke; Pierre Meneton; Marian L Miller; Manoocher Soleimani; Lara R Gawenis; Tara M Riddle; JJ Duffy; Thomas Doetschman; T Wang; Gerhard Giebisch; Peter S Aronson; John N Lorenz; Gary E Shull
Renal and intestinal absorptive defects in mice lacking the NHE3 Na+/H+ exchanger.
Nature genetics 1998;19(3):282-5.
1998: Charles E Burnham; Michael Flagella; Z w Wang; Hassane Amlal; Gary E Shull; Manoocher Soleimani
Cloning, renal distribution, and regulation of the rat Na+-HCO3- cotransporter.
The American journal of physiology 1998;274(6 Pt 2):F1119-26.
1998: Z w Wang; Hamid Rabb; M Haq; Gary E Shull; Manoocher Soleimani
A possible molecular basis of natriuresis during ischemic-reperfusion injury in the kidney.
Journal of the American Society of Nephrology : JASN 1998;9(4):605-13.
1998: Patrick J Schultheis; Lane L Clarke; Pierre Meneton; MC Harline; Gregory P Boivin; Grant N Stemmermann; JJ Duffy; Thomas Doetschman; Marian L Miller; Gary E Shull
Targeted disruption of the murine Na+/H+ exchanger isoform 2 gene causes reduced viability of gastric parietal cells and loss of net acid secretion.
The Journal of clinical investigation 1998;101(6):1243-53.
1998: Pierre Meneton; Patrick J Schultheis; J Greeb; Michelle L Nieman; Lynne H Liu; Lane L Clarke; JJ Duffy; Thomas Doetschman; John N Lorenz; Gary E Shull
Increased sensitivity to K+ deprivation in colonic H,K-ATPase-deficient mice.
The Journal of clinical investigation 1998;101(3):536-42.
1997: Lynne H Liu; Richard J Paul; Roy L Sutliff; Marian L Miller; John N Lorenz; Raymund Y K Pun; JJ Duffy; Thomas Doetschman; Y Kimura; David H MacLennan; James B Hoying; Gary E Shull
Defective endothelium-dependent relaxation of vascular smooth muscle and endothelial cell Ca2+ signaling in mice lacking sarco(endo)plasmic reticulum Ca2+-ATPase isoform 3.
The Journal of biological chemistry 1997;272(48):30538-45.
1997: Charles E Burnham; Hassane Amlal; Z w Wang; Gary E Shull; Manoocher Soleimani
Cloning and functional expression of a human kidney Na+:HCO3- cotransporter.
The Journal of biological chemistry 1997;272(31):19111-4.
1997: Z w Wang; Hamid Rabb; T Craig; Charles E Burnham; Gary E Shull; Manoocher Soleimani
Ischemic-reperfusion injury in the kidney: overexpression of colonic H+-K+-ATPase and suppression of NHE-3.
Kidney international 1997;51(4):1106-15.
1996: B G Pathak; J D Shaughnessy; Pierre Meneton; J Greeb; Gary E Shull; Nancy A Jenkins; Neal G Copeland
Mouse chromosomal location of three epithelial sodium channel subunit genes and an apical sodium chloride cotransporter gene.
Genomics 1996;33(1):124-7.
1996: Z Wang; Patrick J Schultheis; Gary E Shull
Three N-terminal variants of the AE2 Cl-/HCO3- exchanger are encoded by mRNAs transcribed from alternative promoters.
The Journal of biological chemistry 1996;271(13):7835-43.
1996: Marc Cougnon; Gabrielle Planelles; M S Crowson; Gary E Shull; Bernard C Rossier; Frederic Jaisser
The rat distal colon P-ATPase alpha subunit encodes a ouabain-sensitive H+, K+-ATPase.
The Journal of biological chemistry 1996;271(13):7277-80.
1996: B G Pathak; Gary E Shull; Nancy A Jenkins; Neal G Copeland
Mouse chromosomal location of four Na/H exchanger isoform genes.
Genomics 1996;31(2):261-3.
1995: S E Burk; Anil G Menon; Gary E Shull
Analysis of the 5' end of the rat plasma membrane Ca(2+)-ATPase isoform 3 gene and identification of extensive trinucleotide repeat sequences in the 5' untranslated region.
Biochimica et biophysica acta 1995;1240(2):119-24.
1995: S C Linn; G R Askew; Anil G Menon; Gary E Shull
Conservation of an AE3 Cl-/HCO3- exchanger cardiac-specific exon and promoter region and AE3 mRNA expression patterns in murine and human hearts.
Circulation research 1995;76(4):584-91.
1995: T P Keeton; Gary E Shull
Primary structure of rat plasma membrane Ca(2+)-ATPase isoform 4 and analysis of alternative splicing patterns at splice site A.
The Biochemical journal 1995;306 ( Pt 3)():779-85.
1994: Y R Su; C A Klanke; T W Houseal; S C Linn; S E Burk; T S Varvil; Britt Otterud; Gary E Shull; M F Leppert; Anil G Menon
Molecular cloning and physical and genetic mapping of the human anion exchanger isoform 3 (SLC2C) gene to chromosome 2q36.
Genomics 1994;22(3):605-9.
1993: Z Wang; John Orlowski; Gary E Shull
Primary structure and functional expression of a novel gastrointestinal isoform of the rat Na/H exchanger.
The Journal of biological chemistry 1993;268(16):11925-8.
1993: K E Kudrycki; Gary E Shull
Rat kidney band 3 Cl-/HCO3- exchanger mRNA is transcribed from an alternative promoter.
The American journal of physiology 1993;264(3 Pt 2):F540-7.
1993: T P Keeton; S E Burk; Gary E Shull
Alternative splicing of exons encoding the calmodulin-binding domains and C termini of plasma membrane Ca(2+)-ATPase isoforms 1, 2, 3, and 4.
The Journal of biological chemistry 1993;268(4):2740-8.
1992: Gary E Shull; D M Clarke; A M Gunteski-Hamblin
cDNA cloning of possible mammalian homologs of the yeast secretory pathway Ca(2+)-transporting ATPase.
Annals of the New York Academy of Sciences 1992;671():70-80; discussion 81.
1992: S E Burk; Gary E Shull
Structure of the rat plasma membrane Ca(2+)-ATPase isoform 3 gene and characterization of alternative splicing and transcription products. Skeletal muscle-specific splicing results in a plasma membrane Ca(2+)-ATPase with a novel calmodulin-binding domain.
The Journal of biological chemistry 1992;267(27):19683-90.
1992: A M Gunteski-Hamblin; D M Clarke; Gary E Shull
Molecular cloning and tissue distribution of alternatively spliced mRNAs encoding possible mammalian homologues of the yeast secretory pathway calcium pump.
Biochemistry 1992;31(33):7600-8.
1992: Jonathan Lytton; M Westlin; S E Burk; Gary E Shull; D H MacLennan
Functional comparisons between isoforms of the sarcoplasmic or endoplasmic reticulum family of calcium pumps.
The Journal of biological chemistry 1992;267(20):14483-9.
1992: M S Crowson; Gary E Shull
Isolation and characterization of a cDNA encoding the putative distal colon H+,K(+)-ATPase. Similarity of deduced amino acid sequence to gastric H+,K(+)-ATPase and Na+,K(+)-ATPase and mRNA expression in distal colon, kidney, and uterus.
The Journal of biological chemistry 1992;267(19):13740-8.
1992: MA Fiedler; Z K Nemecz; Gary E Shull
Cloning and sequence analysis of rat cystic fibrosis transmembrane conductance regulator.
The American journal of physiology 1992;262(6 Pt 1):L779-84.
1992: S C Linn; K E Kudrycki; Gary E Shull
The predicted translation product of a cardiac AE3 mRNA contains an N terminus distinct from that of the brain AE3 Cl-/HCO3- exchanger. Cloning of a cardiac AE3 cDNA, organization of the AE3 gene, and identification of an alternative transcription initiation site.
The Journal of biological chemistry 1992;267(11):7927-35.
1991: P R Newman; Gary E Shull
Rat gastric H,K-ATPase beta-subunit gene: intron/exon organization, identification of multiple transcription initiation sites, and analysis of the 5'-flanking region.
Genomics 1991;11(2):252-62.
1990: P R Newman; J Greeb; T P Keeton; A A Reyes; Gary E Shull
Structure of the human gastric H,K-ATPase gene and comparison of the 5'-flanking sequences of the human and rat genes.
DNA and cell biology 1990;9(10):749-62.
1990: Gary E Shull
cDNA cloning of the beta-subunit of the rat gastric H,K-ATPase.
The Journal of biological chemistry 1990;265(21):12123-6.
1990: K E Kudrycki; P R Newman; Gary E Shull
cDNA cloning and tissue distribution of mRNAs for two proteins that are related to the band 3 Cl-/HCO3- exchanger.
The Journal of biological chemistry 1990;265(1):462-71.
1989: S E Burk; Jonathan Lytton; D H MacLennan; Gary E Shull
cDNA cloning, functional expression, and mRNA tissue distribution of a third organellar Ca2+ pump.
The Journal of biological chemistry 1989;264(31):18561-8.
1989: J Greeb; Gary E Shull
Molecular cloning of a third isoform of the calmodulin-sensitive plasma membrane Ca2+-transporting ATPase that is expressed predominantly in brain and skeletal muscle.
The Journal of biological chemistry 1989;264(31):18569-76.
1989: K E Kudrycki; Gary E Shull
Primary structure of the rat kidney band 3 anion exchange protein deduced from a cDNA.
The Journal of biological chemistry 1989;264(14):8185-92.
1988: A M Gunteski-Hamblin; J Greeb; Gary E Shull
A novel Ca2+ pump expressed in brain, kidney, and stomach is encoded by an alternative transcript of the slow-twitch muscle sarcoplasmic reticulum Ca-ATPase gene. Identification of cDNAs encoding Ca2+ and other cation-transporting ATPases using an oligonucleotide probe derived from the ATP-binding site.
The Journal of biological chemistry 1988;263(29):15032-40.
1988: Gary E Shull; J Greeb
Molecular cloning of two isoforms of the plasma membrane Ca2+-transporting ATPase from rat brain. Structural and functional domains exhibit similarity to Na+,K+- and other cation transport ATPases.
The Journal of biological chemistry 1988;263(18):8646-57.
1988: Gary E Shull; R M Young; J Greeb; Jerry B Lingrel
Overview: amino acid sequences of the alpha and beta subunits of the Na,K-ATPase.
Progress in clinical and biological research 1988;268A():3-18.
1987: R M Young; Gary E Shull; Jerry B Lingrel
Multiple mRNAs from rat kidney and brain encode a single Na+,K+-ATPase beta subunit protein.
The Journal of biological chemistry 1987;262(10):4905-10.
1986: Gary E Shull; J Greeb; Jerry B Lingrel
Molecular cloning of three distinct forms of the Na+,K+-ATPase alpha-subunit from rat brain.
Biochemistry 1986;25(25):8125-32.