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Antonio Sica

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Antonio Sica; Giovanni Melillo; Luigi Varesio
Hypoxia: a double-edged sword of immunity.
Ferdinando Pucci; Mary Anna Venneri; Daniela Biziato; Alessandro Nonis; Davide Moi; Antonio Sica; Clelia Di Serio; Luigi Naldini; Michele De Palma
A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships.
Alberto Mantovani; Antonio Sica; Paola Allavena; Cecilia Garlanda; Massimo Locati
Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation.

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All Publications

2011: Antonio Sica; Giovanni Melillo; Luigi Varesio
Hypoxia: a double-edged sword of immunity.
Journal of molecular medicine (Berlin, Germany) 2011;89(7):657-65.
2009: Ferdinando Pucci; Mary Anna Venneri; Daniela Biziato; Alessandro Nonis; Davide Moi; Antonio Sica; Clelia Di Serio; Luigi Naldini; Michele De Palma
A distinguishing gene signature shared by tumor-infiltrating Tie2-expressing monocytes, blood "resident" monocytes, and embryonic macrophages suggests common functions and developmental relationships.
Blood 2009;114(4):901-14.
2009: Alberto Mantovani; Antonio Sica; Paola Allavena; Cecilia Garlanda; Massimo Locati
Tumor-associated macrophages and the related myeloid-derived suppressor cells as a paradigm of the diversity of macrophage activation.
Human immunology 2009;70(5):325-30.
2008: Alessandra Mancino; Tiziana Schioppa; Paola Larghi; Fabio Pasqualini; Manuela Nebuloni; I-Hsuan Chen; Silvano Sozzani; Jonathan M Austyn; Alberto Mantovani; Antonio Sica
Divergent effects of hypoxia on dendritic cell functions.
Blood 2008;112(9):3723-34.
2008: Alberto Mantovani; Paola Allavena; Antonio Sica; Frances Balkwill
Cancer-related inflammation.
Nature 2008;454(7203):436-44.
2008: Paola Allavena; Cecilia Garlanda; Maria Grazia Borrello; Antonio Sica; Alberto Mantovani
Pathways connecting inflammation and cancer.
Current opinion in genetics & development 2008;18(1):3-10.
2007: Alberto Mantovani; Federica Marchesi; Chiara Porta; Antonio Sica; Paola Allavena
Inflammation and cancer: breast cancer as a prototype.
Breast (Edinburgh, Scotland) 2007;16 Suppl 2():S27-33.
2006: Alessandra Saccani; Tiziana Schioppa; Chiara Porta; Subhra K Biswas; Manuela Nebuloni; Luca Vago; Barbara Bottazzi; Mario P Colombo; Alberto Mantovani; Antonio Sica
p50 nuclear factor-kappaB overexpression in tumor-associated macrophages inhibits M1 inflammatory responses and antitumor resistance.
Cancer research 2006;66(23):11432-40.
2006: Alberto Mantovani; Tiziana Schioppa; Chiara Porta; Paola Allavena; Antonio Sica
Role of tumor-associated macrophages in tumor progression and invasion.
Cancer metastasis reviews 2006;25(3):315-22.
2006: Antonio Sica; Tiziana Schioppa; Alberto Mantovani; Paola Allavena
Tumour-associated macrophages are a distinct M2 polarised population promoting tumour progression: potential targets of anti-cancer therapy.
European journal of cancer (Oxford, England : 1990) 2006;42(6):717-27.
2006: Subhra K Biswas; Lisa Gangi; Saki Paul; Tiziana Schioppa; Alessandra Saccani; Marina Sironi; Barbara Bottazzi; Andrea Doni; Bronte Vincenzo; Fabio Pasqualini; Luca Vago; Manuela Nebuloni; Alberto Mantovani; Antonio Sica
A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).
Blood 2006;107(5):2112-22.
2005: Alberto Mantovani; Antonio Sica; Massimo Locati
Macrophage polarization comes of age.
Immunity 2005;23(4):344-6.
2004: Alberto Mantovani; Antonio Sica; Silvano Sozzani; Paola Allavena; Annunciata Vecchi; Massimo Locati
The chemokine system in diverse forms of macrophage activation and polarization.
Trends in immunology 2004;25(12):677-86.
2004: Alberto Mantovani; Paola Allavena; Silvano Sozzani; Annunciata Vecchi; Massimo Locati; Antonio Sica
Chemokines in the recruitment and shaping of the leukocyte infiltrate of tumors.
Seminars in cancer biology 2004;14(3):155-60.
2004: Alberto Mantovani; Silvano Sozzani; Massimo Locati; Tiziana Schioppa; Alessandra Saccani; Paola Allavena; Antonio Sica
Infiltration of tumours by macrophages and dendritic cells: tumour-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes.
Novartis Foundation symposium 2004;256():137-45; discussion 146-8, 259-69.
2003: Tiziana Schioppa; Badarch Uranchimeg; Alessandra Saccani; Subhra K Biswas; Andrea Doni; Annamaria Rapisarda; Sergio Bernasconi; Simona Saccani; Manuela Nebuloni; Luca Vago; Alberto Mantovani; Giovanni Melillo; Antonio Sica
Regulation of the chemokine receptor CXCR4 by hypoxia.
The Journal of experimental medicine 2003;198(9):1391-402.
2003: Alberto Mantovani; Tiziana Schioppa; Subhra K Biswas; Federica Marchesi; Paola Allavena; Antonio Sica
Tumor-associated macrophages and dendritic cells as prototypic type II polarized myeloid populations.
Tumori 2003;89(5):459-68.
2003: Priscilla Biswas; Barbara Mantelli; Antonio Sica; Mauro S Malnati; Carla Panzeri; Alessandra Saccani; Hamid Hasson; Annunciata Vecchi; Abby R Saniabadi; Paolo Lusso; Adriano Lazzarin; Alberto Beretta
Expression of CD4 on human peripheral blood neutrophils.
Blood 2003;101(11):4452-6.
2002: Alberto Mantovani; Silvano Sozzani; Massimo Locati; Paola Allavena; Antonio Sica
Macrophage polarization: tumor-associated macrophages as a paradigm for polarized M2 mononuclear phagocytes.
Trends in immunology 2002;23(11):549-55.
2002: Antonio Sica; Alessandra Saccani; Alberto Mantovani
Tumor-associated macrophages: a molecular perspective.
International immunopharmacology 2002;2(8):1045-54.
2002: Pia Villa; Alessandra Saccani; Antonio Sica; Pietro Ghezzi
Glutathione protects mice from lethal sepsis by limiting inflammation and potentiating host defense.
The Journal of infectious diseases 2002;185(8):1115-20.
2002: Lorenzo Piemonti; Biagio Eugenio Leone; Rita Nano; Alessandra Saccani; Paolo Monti; Paola Maffi; Giancarlo Bianchi; Antonio Sica; Giuseppe Peri; Raffaella Melzi; Luca Aldrighetti; Antonio Secchi; Valerio Di Carlo; Paola Allavena; Federico Bertuzzi
Human pancreatic islets produce and secrete MCP-1/CCL2: relevance in human islet transplantation.
Diabetes 2002;51(1):55-65.
2000: Alessandra Saccani; Simona Saccani; S Orlando; Marina Sironi; Sergio Bernasconi; Pietro Ghezzi; Alberto Mantovani; Antonio Sica
Redox regulation of chemokine receptor expression.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(6):2761-6.
2000: Antonio Sica; Alessandra Saccani; Barbara Bottazzi; Nadia Polentarutti; Annunciata Vecchi; Jo Van Damme; Alberto Mantovani
Autocrine production of IL-10 mediates defective IL-12 production and NF-kappa B activation in tumor-associated macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):762-7.
2000: Antonio Sica; Alessandra Saccani; Barbara Bottazzi; Sergio Bernasconi; Paola Allavena; B Gaetano; F Fei; G LaRosa; Chris J Scotton; Frances R Balkwill; Alberto Mantovani
Defective expression of the monocyte chemotactic protein-1 receptor CCR2 in macrophages associated with human ovarian carcinoma.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(2):733-8.
1999: G Penton Rol; M Cota; Nadia Polentarutti; Walter Luini; Sergio Bernasconi; A Borsatti; Antonio Sica; Greg La Rosa; Silvano Sozzani; Guido Poli; Alberto Mantovani
Up-regulation of CCR2 chemokine receptor expression and increased susceptibility to the multitropic HIV strain 89.6 in monocytes exposed to glucocorticoid hormones.
Journal of immunology (Baltimore, Md. : 1950) 1999;163(6):3524-9.
1999: Simona Saccani; Alessandra Saccani; L Varesio; P Ghosh; H A Young; Antonio Sica
Divergent effects of dithiocarbamates on AP-1-containing and AP-1-less NFAT sites.
European journal of immunology 1999;29(4):1194-201.
1998: G Penton Rol; Nadia Polentarutti; Walter Luini; A Borsatti; R Mancinelli; Antonio Sica; Silvano Sozzani; Alberto Mantovani
Selective inhibition of expression of the chemokine receptor CCR2 in human monocytes by IFN-gamma.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(8):3869-73.
1998: Silvano Sozzani; Silvia Ghezzi; gioacchin iannolo; Walter Luini; A Borsatti; Nadia Polentarutti; Antonio Sica; Massimo Locati; C Mackay; Timothy Wells; Priscilla Biswas; Elisa Vicenzi; Guido Poli; Alberto Mantovani
Interleukin 10 increases CCR5 expression and HIV infection in human monocytes.
The Journal of experimental medicine 1998;187(3):439-44.
1997: Silvano Sozzani; Martino Introna; Sergio Bernasconi; Nadia Polentarutti; P Cinque; Guido Poli; Antonio Sica; Alberto Mantovani
MCP-1 and CCR2 in HIV infection: regulation of agonist and receptor expression.
Journal of leukocyte biology 1997;62(1):30-3.
1997: Antonio Sica; Alessandra Saccani; A Borsatti; CA Power; Timothy Wells; Walter Luini; Nadia Polentarutti; Silvano Sozzani; Alberto Mantovani
Bacterial lipopolysaccharide rapidly inhibits expression of C-C chemokine receptors in human monocytes.
The Journal of experimental medicine 1997;185(5):969-74.