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François Sichel

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F Petitpas; Didier Pottier; François Sichel; M Beljean; B Hébert; S Lagadu; M Laurentie; V Prevost
Effects of alcohol consumption on biomarkers of oxidative damage to DNA and lipids in ethanol-fed pigs.
Imane Abbas; Véronique Andre; Sylvain Billet; Guillaume Garçon; J Le Goff; Pierre Gosset; Philippe Mulliez; F Saint Georges; François Sichel; Anthony Verdin; Pirouz Shirali
Polycyclic aromatic hydrocarbons within airborne particulate matter (PM(2.5)) produced DNA bulky stable adducts in a human lung cell coculture model.
Vincent PAGET; Didier Pottier; Pirouz Shirali; Véronique André; Sylvain Billet; Guillaume Garçon; Mathilde Lechevrel; J Le Goff; François Sichel
Benzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiology.

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All Publications

2013: F Petitpas; Didier Pottier; François Sichel; M Beljean; B Hébert; S Lagadu; M Laurentie; V Prevost
Effects of alcohol consumption on biomarkers of oxidative damage to DNA and lipids in ethanol-fed pigs.
Experimental and toxicologic pathology : official journal of the Gesellschaft für Toxikologische Pathologie 2013;65(3):263-9.
2013: Imane Abbas; Véronique Andre; Sylvain Billet; Guillaume Garçon; J Le Goff; Pierre Gosset; Philippe Mulliez; F Saint Georges; François Sichel; Anthony Verdin; Pirouz Shirali
Polycyclic aromatic hydrocarbons within airborne particulate matter (PM(2.5)) produced DNA bulky stable adducts in a human lung cell coculture model.
Journal of applied toxicology : JAT 2013;33(2):109-19.
2012: Vincent PAGET; Didier Pottier; Pirouz Shirali; Véronique André; Sylvain Billet; Guillaume Garçon; Mathilde Lechevrel; J Le Goff; François Sichel
Benzo[a]pyrene, aflatoxine B₁ and acetaldehyde mutational patterns in TP53 gene using a functional assay: relevance to human cancer aetiology.
PloS one 2012;7(2):e30921.
2011: Véronique André; S Billet; Didier Pottier; J Le Goff; Ivannah Pottier; G Garçon; P Shirali; François Sichel
Mutagenicity and genotoxicity of PM2.5 issued from an urbano-industrialized area of Dunkerque (France).
Journal of applied toxicology : JAT 2011;31(2):131-8.
2010: Stéphanie Lagadu; Ivannah Pottier; François Sichel; Carine Laurent; Jean-Louis Lefaix; Virginie Prevost
Detection of extracellular 8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in X-irradiated fibroblast cultures: optimization of analytical procedure.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals 2010;15(8):707-14.
2010: Pauline Bidaud; Jacques Chasle; François Sichel; Stéphane Rousseau; Pascal Petit; Didier Pottier; Jean-Michel Picquenot; Marie-Yolande Louis; Mathilde Lechevrel
Expression of p53 family members and CD44 in oral squamous cell carcinoma (OSCC) in relation to tumorigenesis.
Histology and histopathology 2010;25(3):331-9.
2010: Sylvain Billet; Vincent PAGET; Guillaume Garçon; Natacha Heutte; Véronique André; Pirouz Shirali; François Sichel
Benzene-induced mutational pattern in the tumour suppressor gene TP53 analysed by use of a functional assay, the functional analysis of separated alleles in yeast, in human lung cells.
Archives of toxicology 2010;84(2):99-107.
2010: Stéphanie Lagadu; Mathilde Lechevrel; François Sichel; Jean Breton; Didier Pottier; Rémy Couderc; Fathi Moussa; Virginie Prevost
8-oxo-7,8-dihydro-2'-deoxyguanosine as a biomarker of oxidative damage in oesophageal cancer patients: lack of association with antioxidant vitamins and polymorphism of hOGG1 and GST.
Journal of experimental & clinical cancer research : CR 2010;29():157.
2008: Vincent PAGET; François Sichel; David Garon; Mathilde Lechevrel
Aflatoxin B1-induced TP53 mutational pattern in normal human cells using the FASAY (Functional Analysis of Separated Alleles in Yeast).
Mutation research 2008;656(1-2):55-61.
2008: Vincent PAGET; Mathilde Lechevrel; François Sichel
Acetaldehyde-induced mutational pattern in the tumour suppressor gene TP53 analysed by use of a functional assay, the FASAY (functional analysis of separated alleles in yeast).
Mutation research 2008;652(1):12-9.
2006: Ahmed Abbas; Mathilde Lechevrel; François Sichel
Identification of new single nucleotid polymorphisms (SNP) in alcohol dehydrogenase class IV ADH7 gene within a French population.
Archives of toxicology 2006;80(4):201-5.
2006: Jean Breton; Mathilde Lechevrel; François Sichel
Specificity of TP53 mutation screening methods in cancerous tissues.
International journal of cancer. Journal international du cancer 2006;118(1):254-5; author reply 256.
2005: Jean Breton; François Sichel; Didier Pottier; Virginie Prevost
Measurement of 8-oxo-7,8-dihydro-2'-deoxyguanosine in peripheral blood mononuclear cells: optimisation and application to samples from a case-control study on cancers of the oesophagus and cardia.
Free radical research 2005;39(1):21-30.
2004: Ahmed Abbas; Karine Delvinquiere; Mathilde Lechevrel; Pierre Lebailly; Pascal Gauduchon; Guy Launoy; François Sichel
GSTM1, GSTT1, GSTP1 and CYP1A1 genetic polymorphisms and susceptibility to esophageal cancer in a French population: different pattern of squamous cell carcinoma and adenocarcinoma.
World journal of gastroenterology : WJG 2004;10(23):3389-93.
2004: Ahmed Abbas; Maud Lepelley; Mathilde Lechevrel; François Sichel
Assessment of DHPLC usefulness in the genotyping of GSTP1 exon 5 SNP: comparison to the PCR-RFLP method.
Journal of biochemical and biophysical methods 2004;59(2):121-6.
2004: Annie Canu; Ahmed Abbas; Brigitte Malbruny; François Sichel; Roland Leclercq
Denaturing high-performance liquid chromatography detection of ribosomal mutations conferring macrolide resistance in gram-positive cocci.
Antimicrobial agents and chemotherapy 2004;48(1):297-304.
2003: Jean Breton; François Sichel; Ahmed Abbas; Jacques Marnay; Dominique Arsène; Mathilde Lechevrel
Simultaneous use of DGGE and DHPLC to screen TP53 mutations in cancers of the esophagus and cardia from a European high incidence area (Lower Normandy, France).
Mutagenesis 2003;18(3):299-306.
2002: Thierry Godard; Edwige Deslandes; François Sichel; Jean-Michel Poul; Pascal Gauduchon
Detection of topoisomerase inhibitor-induced DNA strand breaks and apoptosis by the alkaline comet assay.
Mutation research 2002;520(1-2):47-56.
2002: Sylvie Maubant; Séverine Cruet-Hennequart; Laurent Poulain; Franck Carreiras; François Sichel; José Luis; Cathy Staedel; Pascal Gauduchon
Altered adhesion properties and alphav integrin expression in a cisplatin-resistant human ovarian carcinoma cell line.
International journal of cancer. Journal international du cancer 2002;97(2):186-94.
2000: Vladimir N Anisimov; Mark A Zabezhinski; Irina G Popovich; E A Zaripova; SA Musatov; V Andre; C Vigreux; Thierry Godard; François Sichel
Inhibitory effect of melatonin on 7, 12-dimethylbenz[a]anthracene-induced carcinogenesis of the uterine cervix and vagina in mice and mutagenesis in vitro.
Cancer letters 2000;156(2):199-205.
1999: Thierry Godard; Edwige Deslandes; Pierre Lebailly; C Vigreux; François Sichel; Jean-Michel Poul; Pascal Gauduchon
Early detection of staurosporine-induced apoptosis by comet and annexin V assays.
Histochemistry and cell biology 1999;112(2):155-61.
1999: Thierry Godard; Valérie Fessard; S Huet; Annick Mourot; Edwige Deslandes; Didier Pottier; O Hyrien; François Sichel; Pascal Gauduchon; Jean-Michel Poul
Comparative in vitro and in vivo assessment of genotoxic effects of etoposide and chlorothalonil by the comet assay.
Mutation research 1999;444(1):103-16.
1999: Thierry Godard; Edwige Deslandes; Pierre Lebailly; C Vigreux; Laurent Poulain; François Sichel; Jean-Michel Poul; Pascal Gauduchon
Comet assay and DNA flow cytometry analysis of staurosporine-induced apoptosis.
Cytometry 1999;36(2):117-22.
1999: SA Musatov; Vladimir N Anisimov; Véronique André; C Vigreux; Thierry Godard; François Sichel
Effects of melatonin on N-nitroso-N-methylurea-induced carcinogenesis in rats and mutagenesis in vitro (Ames test and COMET assay).
Cancer letters 1999;138(1-2):37-44.
1999: Franck Carreiras; S Cruet; Cathy Staedel; François Sichel; Pascal Gauduchon
Human ovarian adenocarcinoma cells synthesize vitronectin and use It to organize their adhesion.
Gynecologic oncology 1999;72(3):312-22.
1998: C Vigreux; Jean-Michel Poul; Edwige Deslandes; Pierre Lebailly; Thierry Godard; François Sichel; Michel Henry-Amar; Pascal Gauduchon
DNA damaging effects of pesticides measured by the single cell gel electrophoresis assay (comet assay) and the chromosomal aberration test, in CHOK1 cells.
Mutation research 1998;419(1-3):79-90.
1998: Laurent Poulain; Hubert Lincet; Françoise Duigou; Edwige Deslandes; François Sichel; Pascal Gauduchon; Cathy Staedel
Acquisition of chemoresistance in a human ovarian carcinoma cell is linked to a defect in cell cycle control.
International journal of cancer. Journal international du cancer 1998;78(4):454-63.
1998: Pierre Lebailly; C Vigreux; C Lechevrel; D Ledemeney; Thierry Godard; François Sichel; JY LeTalaër; Michel Henry-Amar; Pascal Gauduchon
DNA damage in mononuclear leukocytes of farmers measured using the alkaline comet assay: modifications of DNA damage levels after a one-day field spraying period with selected pesticides.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(10):929-40.
1998: Pierre Lebailly; C Vigreux; C Lechevrel; D Ledemeney; Thierry Godard; François Sichel; JY LeTalaër; Michel Henry-Amar; Pascal Gauduchon
DNA damage in mononuclear leukocytes of farmers measured using the alkaline comet assay: discussion of critical parameters and evaluation of seasonal variations in relation to pesticide exposure.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 1998;7(10):917-27.
1998: SA Musatov; Vladimir N Anisimov; Véronique André; C Vigreux; Thierry Godard; Pascal Gauduchon; François Sichel
Modulatory effects of melatonin on genotoxic response of reference mutagens in the Ames test and the comet assay.
Mutation research 1998;417(2-3):75-84.
1997: Pierre Lebailly; C Vigreux; Thierry Godard; François Sichel; E Bar; JY LeTalaër; Michel Henry-Amar; Pascal Gauduchon
Assessment of DNA damage induced in vitro by etoposide and two fungicides (carbendazim and chlorothalonil) in human lymphocytes with the comet assay.
Mutation research 1997;375(2):205-17.
1997: Véronique André; C Boissart; François Sichel; Pascal Gauduchon; JY Le Talaër; Jean-Charles Lancelot; C Mercier; S Chemtob; E Raoult; A Tallec
Mutagenicity of nitro- and amino-substituted carbazoles in Salmonella typhimurium. III. Methylated derivatives of 9H-carbazole.
Mutation research 1997;389(2-3):247-60.
1997: Laurent Poulain; François Sichel; Hubert Crouet; F Bureau; Pascal Gauduchon; M Gignoux; JY Le Talaër
Potentiation of cisplatin and carboplatin cytotoxicity by amphotericin B in different human ovarian carcinoma and malignant peritoneal mesothelioma cells.
Cancer chemotherapy and pharmacology 1997;40(5):385-90.
1996: Franck Carreiras; Y Denoux; Cathy Staedel; M Lehmann; François Sichel; Pascal Gauduchon
Expression and localization of alpha v integrins and their ligand vitronectin in normal ovarian epithelium and in ovarian carcinoma.
Gynecologic oncology 1996;62(2):260-7.
1995: Franck Carreiras; M Lehmann; François Sichel; Jacques Marvaldi; Pascal Gauduchon; J Y Le Talaer
Implication of the alpha v beta 3 integrin in the adhesion of the ovarian-adenocarcinoma cell line IGROV1.
International journal of cancer. Journal international du cancer 1995;63(4):530-6.
1995: Véronique André; C Boissart; François Sichel; Pascal Gauduchon; J Y Le Talaër; Jean-Charles Lancelot; M Robba; C Mercier; S Chemtob; E Raoult
Mutagenicity of nitro- and amino-substituted carbazoles in Salmonella typhimurium. II. Ortho-aminonitro derivatives of 9H-carbazole.
Mutation research 1995;345(1-2):11-25.
1995: E Bar; François Sichel; F Guerin; Pascal Gauduchon; D Asselin; J Y Le Talaer
Serum galactosyltransferase activities in newborn children and pregnant women.
Annales de biologie clinique 1995;53(1-2):33-5.
1994: François Sichel; V Salaün; E Bar; Pascal Gauduchon; J P Malas; J Goussard; J Y Le Talaër
Biological markers and ovarian carcinomas: galactosyltransferase, CA 125, isoenzymes of amylase and alkaline phosphatase.
Clinica chimica acta; international journal of clinical chemistry 1994;227(1-2):87-96.
1991: François Sichel; E Bar; Pascal Gauduchon; J P Malas; J Benard; J Y Le Talaer
[Localization and modulation of galactosyltransferase during in vitro proliferation of a human ovarian adenocarcinoma cell line].
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1991;312(1):19-24.
1990: François Sichel; J P Malas; Pascal Gauduchon; M Aubert; E Bar; J Y Le Talaër
A simple serum galactosyltransferase assay method suitable for routine use.
Clinica chimica acta; international journal of clinical chemistry 1990;188(1):49-58.
1990: J P Malas; E Bar; Pascal Gauduchon; François Sichel; J Y Le Talaer
Alteration in isoenzyme patterns of serum galactosyltransferase activity in ovarian cancer patients: preliminary results.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1990;44(6):325-31.
1988: Pascal Gauduchon; E Bar; J P Malas; M Aubert; François Sichel; J Y Le Talaër
Serum galactosyltransferase activity with three acceptors in ovarian cancer patients.
European journal of cancer & clinical oncology 1988;24(7):1157-62.
1988: E Bar; J P Malas; Pascal Gauduchon; M Aubert; François Sichel; P Y Bedard; J Y Le Talaer
[Comparative study of various technics for the determination of human serum galactosyltransferase].
Annales de biologie clinique 1988;46(2):123-8.