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Yunxin Bo

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Ryan P Wurz; Kevin Yang; Nancy Zhang; Liping H Pettus; Raju Subramanian; Ling Wang; Douglas A Whittington; Kristin L Andrews; Yunxin Bo; Sean Caenepeel; Daniel J Freeman; Paul E Hughes; Jian Jiang; Longbin Liu; John D McCarter; Tisha San Miguel; Erin L Mullady; Nobuko Nishimura; Mark H Norman
Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold.
Nuria A Tamayo; Phi Tang; Weiya Wang; Brad Youngblood; Michael D Bartberger; Yunxin Bo; Jiyun Chen; Tiffany L Correll; Hong Deng; Narender R Gavva; Vijay K Gore; Lana Klionsky; Sonya G Lehto; Vu V Ma; Nobuko Nishimura; Mark H Norman
Fused piperidines as a novel class of potent and orally available transient receptor potential melastatin type 8 (TRPM8) antagonists.
Nobuko Nishimura; Kristin L Andrews; Yunxin Bo; Shon K Booker; Marian C Bryan; Sean Caenepeel; Daniel Freeman; Paul E Hughes; Hongyu Liao; Longbin Liu; John McCarter; Erin L Mullady; Tisha San Miguel; Aaron Siegmund; Raju Subramanian; Nuria A Tamayo; Ling Wang; Douglas A Whittington; Kevin Yang; Leeanne Zalameda; Nancy Zhang; Mark H Norman
Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: discovery and structure-activity relationships of a series of quinoline and quinoxaline derivatives.

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All Publications

2012: Ryan P Wurz; Kevin Yang; Nancy Zhang; Liping H Pettus; Raju Subramanian; Ling Wang; Douglas A Whittington; Kristin L Andrews; Yunxin Bo; Sean Caenepeel; Daniel J Freeman; Paul E Hughes; Jian Jiang; Longbin Liu; John D McCarter; Tisha San Miguel; Erin L Mullady; Nobuko Nishimura; Mark H Norman
Synthesis and structure-activity relationships of dual PI3K/mTOR inhibitors based on a 4-amino-6-methyl-1,3,5-triazine sulfonamide scaffold.
Bioorganic & medicinal chemistry letters 2012;22(17):5714-20.
2012: Nuria A Tamayo; Phi Tang; Weiya Wang; Brad Youngblood; Michael D Bartberger; Yunxin Bo; Jiyun Chen; Tiffany L Correll; Hong Deng; Narender R Gavva; Vijay K Gore; Lana Klionsky; Sonya G Lehto; Vu V Ma; Nobuko Nishimura; Mark H Norman
Fused piperidines as a novel class of potent and orally available transient receptor potential melastatin type 8 (TRPM8) antagonists.
Journal of medicinal chemistry 2012;55(4):1593-611.
2011: Nobuko Nishimura; Kristin L Andrews; Yunxin Bo; Shon K Booker; Marian C Bryan; Sean Caenepeel; Daniel Freeman; Paul E Hughes; Hongyu Liao; Longbin Liu; John McCarter; Erin L Mullady; Tisha San Miguel; Aaron Siegmund; Raju Subramanian; Nuria A Tamayo; Ling Wang; Douglas A Whittington; Kevin Yang; Leeanne Zalameda; Nancy Zhang; Mark H Norman
Phospshoinositide 3-kinase (PI3K)/mammalian target of rapamycin (mTOR) dual inhibitors: discovery and structure-activity relationships of a series of quinoline and quinoxaline derivatives.
Journal of medicinal chemistry 2011;54(13):4735-51.
2008: Markian M Stec; Yunxin Bo; Partha P Chakrabarti; Lillian Liao; Mqhele Ncube; Nuria A Tamayo; Rami Tamir; Narender R Gavva; James J S Treanor; Mark H Norman
Substituted aryl pyrimidines as potent and soluble TRPV1 antagonists.
Bioorganic & medicinal chemistry letters 2008;18(18):5118-22.
2007: Elizabeth M Doherty; Christopher Fotsch; Anthony W Bannon; Yunxin Bo; Ning Chen; Celia Dominguez; James Falsey; Narender R Gavva; Jodie Katon; Thomas Nixey; Vassil I Ognyanov; Liping Pettus; Robert M Rzasa; Markian Stec; Sekhar Surapaneni; Rami Tamir; Jiawang Zhu; James J S Treanor; Mark H Norman
Novel vanilloid receptor-1 antagonists: 2. Structure-activity relationships of 4-oxopyrimidines leading to the selection of a clinical candidate.
Journal of medicinal chemistry 2007;50(15):3515-27.
2007: Mark H Norman; Jiawang Zhu; Christopher Fotsch; Yunxin Bo; Ning Chen; Partha P Chakrabarti; Elizabeth M Doherty; Narender R Gavva; Nobuko Nishimura; Thomas Nixey; Vassil I Ognyanov; Robert M Rzasa; Markian Stec; Sekhar Surapaneni; Rami Tamir; Vellarkad Viswanadhan; James J S Treanor
Novel vanilloid receptor-1 antagonists: 1. Conformationally restricted analogues of trans-cinnamides.
Journal of medicinal chemistry 2007;50(15):3497-514.
2006: Vassil I Ognyanov; Chenera Balan; Anthony W Bannon; Yunxin Bo; Celia Dominguez; Christopher Fotsch; Vijay K Gore; Lana Klionsky; Vu V Ma; Yi-Xin Qian; Rami Tamir; Xianghong Wang; Ning Xi; Shimin Xu; Dawn Zhu; Narender R Gavva; James J S Treanor; Mark H Norman
Design of potent, orally available antagonists of the transient receptor potential vanilloid 1. Structure-activity relationships of 2-piperazin-1-yl-1H-benzimidazoles.
Journal of medicinal chemistry 2006;49(12):3719-42.
2005: Ning Xi; Yunxin Bo; Elizabeth M Doherty; Christopher Fotsch; Narender R Gavva; Nianhe Han; Randall W Hungate; Lana Klionsky; Qingyian Liu; Rami Tamir; Shimin Xu; James J S Treanor; Mark H Norman
Synthesis and evaluation of thiazole carboxamides as vanilloid receptor 1 (TRPV1) antagonists.
Bioorganic & medicinal chemistry letters 2005;15(23):5211-7.
2005: Christopher Fotsch; Nianhe Han; Premilla Arasasingham; Yunxin Bo; Michelle Carmouche; Ning Chen; James Davis; Martin H Goldberg; Clarence Hale; Feng-Yin Hsieh; Michael G Kelly; Qingyian Liu; Mark H Norman; Duncan M Smith; Markian Stec; Nuria A Tamayo; Ning Xi; Shimin Xu; Anthony W Bannon; James W Baumgartner
Melanocortin subtype-4 receptor agonists containing a piperazine core with substituted aryl sulfonamides.
Bioorganic & medicinal chemistry letters 2005;15(6):1623-7.
2005: Elizabeth M Doherty; Christopher Fotsch; Yunxin Bo; Partha P Chakrabarti; Ning Chen; Narender R Gavva; Nianhe Han; Michael G Kelly; John Kincaid; Lana Klionsky; Qingyian Liu; Vassil I Ognyanov; Rami Tamir; Xianghong Wang; Jiawang Zhu; Mark H Norman; James J S Treanor
Discovery of potent, orally available vanilloid receptor-1 antagonists. Structure-activity relationship of N-aryl cinnamides.
Journal of medicinal chemistry 2005;48(1):71-90.