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Adam Siddiqui

Research Profile

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TOP 3
Christopher McGuigan; Alshaimaa Hassan-Abdallah; Sheila Srinivasan; Yikang Wang; Adam Siddiqui; Susan M Daluge; Kristjan S Gudmundsson; Huiqiang Zhou; Ed W McLean; Jennifer P Peckham; Thimysta C Burnette; Harry Marr; Richard J Hazen; Lynn Condreay; Lance Johnson; Jan Balzarini
Application of phosphoramidate ProTide technology significantly improves antiviral potency of carbocyclic adenosine derivatives.
Adam Siddiqui; Christopher McGuigan; C Ballatore; Sheila Srinivasan; Erik De Clercq; Jan Balzarini
Enhancing the aqueous solubility of d4T-based phosphoramidate prodrugs.
Christopher McGuigan; D Cahard; C Ballatore; Adam Siddiqui; Erik De Clercq; Jan Balzarini
Lactate cannot substitute for alanine in d4T-based anti-HIV nucleotide prodrugs--despite efficient esterase-mediated hydrolysis.

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All Publications

2006: Christopher McGuigan; Alshaimaa Hassan-Abdallah; Sheila Srinivasan; Yikang Wang; Adam Siddiqui; Susan M Daluge; Kristjan S Gudmundsson; Huiqiang Zhou; Ed W McLean; Jennifer P Peckham; Thimysta C Burnette; Harry Marr; Richard J Hazen; Lynn Condreay; Lance Johnson; Jan Balzarini
Application of phosphoramidate ProTide technology significantly improves antiviral potency of carbocyclic adenosine derivatives.
Journal of medicinal chemistry 2006;49(24):7215-26.
2000: Adam Siddiqui; Christopher McGuigan; C Ballatore; Sheila Srinivasan; Erik De Clercq; Jan Balzarini
Enhancing the aqueous solubility of d4T-based phosphoramidate prodrugs.
Bioorganic & medicinal chemistry letters 2000;10(4):381-4.
1998: Christopher McGuigan; D Cahard; C Ballatore; Adam Siddiqui; Erik De Clercq; Jan Balzarini
Lactate cannot substitute for alanine in d4T-based anti-HIV nucleotide prodrugs--despite efficient esterase-mediated hydrolysis.
Bioorganic & medicinal chemistry letters 1998;8(21):2949-54.

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