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David Sidransky

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Polymerase Chain Reaction

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Publications

TOP 3
Dasgupta Santanu; Hoque Mohammad Obaidul; Upadhyay Sunil; Sidransky David
Forced cytochrome B gene mutation expression induces mitochondrial proliferation and prevents apoptosis in human uroepithelial SV-HUC-1 cells.
Brait Mariana; Ford Jean G; Papaiahgari Srinivas; Garza Mary A; Lee Jin I; Loyo Myriam; Maldonado Leonel; Begum Shahnaz; McCaffrey Lee; Howerton Mollie; Sidransky David; Emerson Mark R; Ahmed Saifuddin; Williams Carla D; Hoque Mohammad Obaidul
Association between lifestyle factors and CpG island methylation in a cancer-free population.
Hoque Mohammad Obaidul; Prencipe Maria; Poeta Maria Luana; Barbano Raffaela; Valori Vanna Maria; Copetti Massimiliano; Gallo Antonietta Pia; Brait Mariana; Maiello Evaristo; Apicella Adolfo; Rossiello Raffaele; Zito Francesco; Stefania Tommasi; Paradiso Angelo; Carella Massimo; Dallapiccola Bruno; Murgo Roberto; Carosi Illuminato; Bisceglia Michele; Fazio Vito Michele; Sidransky David; Parrella Paola
Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression.

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All Publications

2009: Dasgupta Santanu; Hoque Mohammad Obaidul; Upadhyay Sunil; Sidransky David
Forced cytochrome B gene mutation expression induces mitochondrial proliferation and prevents apoptosis in human uroepithelial SV-HUC-1 cells.
International journal of cancer. Journal international du cancer 2009;125(12):2829-35.
2009: Brait Mariana; Ford Jean G; Papaiahgari Srinivas; Garza Mary A; Lee Jin I; Loyo Myriam; Maldonado Leonel; Begum Shahnaz; McCaffrey Lee; Howerton Mollie; Sidransky David; Emerson Mark R; Ahmed Saifuddin; Williams Carla D; Hoque Mohammad Obaidul
Association between lifestyle factors and CpG island methylation in a cancer-free population.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(11):2984-91.
2009: Hoque Mohammad Obaidul; Prencipe Maria; Poeta Maria Luana; Barbano Raffaela; Valori Vanna Maria; Copetti Massimiliano; Gallo Antonietta Pia; Brait Mariana; Maiello Evaristo; Apicella Adolfo; Rossiello Raffaele; Zito Francesco; Stefania Tommasi; Paradiso Angelo; Carella Massimo; Dallapiccola Bruno; Murgo Roberto; Carosi Illuminato; Bisceglia Michele; Fazio Vito Michele; Sidransky David; Parrella Paola
Changes in CpG islands promoter methylation patterns during ductal breast carcinoma progression.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009;18(10):2694-700.
2009: Slager Joram; Tyler Betty; Shikanov Ariella; Domb Abraham J; Shogen Kuslima; Sidransky David; Brem Henry
Local controlled delivery of anti-neoplastic RNAse to the brain.
Pharmaceutical research 2009;26(8):1838-46.
2009: Ha Patrick K; Chang Steven S; Glazer Chad A; Califano Joseph A; Sidransky David
Molecular techniques and genetic alterations in head and neck cancer.
Oral oncology 2009;45(4-5):335-9.
2009: Ostrow Kimberly Laskie; Park Hannah Lui; Hoque Mohammad Obaidul; Kim Myoung Sook; Liu Junwei; Argani Pedram; Westra William; Van Criekinge Wim; Sidransky David
Pharmacologic unmasking of epigenetically silenced genes in breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(4):1184-91.
2009: Kim Myoung Sook; Louwagie Joost; Carvalho Beatriz; Terhaar Sive Droste Jochim S; Park Hannah Lui; Chae Young Kwang; Yamashita Keishi; Liu Junwei; Ostrow Kimberly Laskie; Ling Shizhang; Guerrero-Preston Rafael; Demokan Semra; Yalniz Zubeyde; Dalay Nejat; Meijer Gerrit A; Van Criekinge Wim; Sidransky David
Promoter DNA methylation of oncostatin m receptor-beta as a novel diagnostic and therapeutic marker in colon cancer.
PloS one 2009;4(8):e6555.
2009: Dasgupta Santanu; Yung Rex C; Westra William H; Rini David A; Brandes Johann; Sidransky David
Following mitochondrial footprints through a long mucosal path to lung cancer.
PloS one 2009;4(8):e6533.
2008: Chang Steven S; Jiang Wei Wen; Smith Ian; Poeta Luana M; Begum Shahnaz; Glazer Chad; Shan Shannon; Westra William; Sidransky David; Califano Joseph A
MicroRNA alterations in head and neck squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2008;123(12):2791-7.
2008: Gorelik Boris; Ziv Irit; Shohat Revital; Wick Michael; Hankins W David; Sidransky David; Agur Zvia
Efficacy of weekly docetaxel and bevacizumab in mesenchymal chondrosarcoma: a new theranostic method combining xenografted biopsies with a mathematical model.
Cancer research 2008;68(21):9033-40.
2008: Brait Mariana; Begum Shahnaz; Carvalho André L; Dasgupta Santanu; Vettore André L; Czerniak Bogdan; Caballero Otávia L; Westra William H; Sidransky David; Hoque Mohammad Obaidul
Aberrant promoter methylation of multiple genes during pathogenesis of bladder cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2008;17(10):2786-94.
2008: Huang Yiping; Sen Tanusree; Nagpal Jatin; Upadhyay Sunil; Trink Barry; Ratovitski Edward; Sidransky David
ATM kinase is a master switch for the Delta Np63 alpha phosphorylation/degradation in human head and neck squamous cell carcinoma cells upon DNA damage.
Cell cycle (Georgetown, Tex.) 2008;7(18):2846-55.
2008: Kang Sung Koo; Chae Young Kwang; Woo Janghee; Kim Myoung Sook; Park Jong Chul; Lee Juna; Soria Jean Charles; Jang Se Jin; Sidransky David; Moon Chulso
Role of human aquaporin 5 in colorectal carcinogenesis.
The American journal of pathology 2008;173(2):518-25.
2008: Tokumaru Yutaka; Yamashita Keishi; Kim Myoung Sook; Park Hannah L; Osada Motonobu; Mori Masaki; Sidransky David
The role of PGP9.5 as a tumor suppressor gene in human cancer.
International journal of cancer. Journal international du cancer 2008;123(4):753-9.
2008: Nagpal Jatin K; Dasgupta Santanu; Jadallah Sana; Chae Young K; Ratovitski Edward A; Toubaji Antoun; Netto George J; Eagle Toby; Nissan Aviram; Sidransky David; Trink Barry
Profiling the expression pattern of GPI transamidase complex subunits in human cancer.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2008;21(8):979-91.
2008: Sidransky David
The oral cavity as a molecular mirror of lung carcinogenesis.
Cancer prevention research (Philadelphia, Pa.) 2008;1(1):12-4.
2008: Liu Jun-Wei; Nagpal Jatin K; Sun Wenyue; Lee Juna; Kim Myoung Sook; Ostrow Kimberly L; Zhou Shaoyu; Jeronimo Carmen; Henrique Rui; Van Criekinge Wim; Moon Chu So; Califano Joseph A; Trink Barry; Sidransky David
ssDNA-binding protein 2 is frequently hypermethylated and suppresses cell growth in human prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(12):3754-60.
2008: Huang Yiping; Hoque Mohammad Obaidul; Wu Feng; Trink Barry; Sidransky David; Ratovitski Edward A
Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes.
Cell cycle (Georgetown, Tex.) 2008;7(11):1613-22.
2008: Woo Janghee; Lee Juna; Chae Young Kwang; Kim Myoung Sook; Baek Jin Hyen; Park Jong Chul; Park Min Joo; Smith Ian M; Trink Barry; Ratovitski Edward; Lee Taekyul; Park Bumsoo; Jang Se Jin; Soria Jean C; Califano Joseph A; Sidransky David; Moon Chulso
Overexpression of AQP5, a putative oncogene, promotes cell growth and transformation.
Cancer letters 2008;264(1):54-62.
2008: Park Hannah Lui; Kim Myoung Sook; Yamashita Keishi; Westra William; Carvalho Andre Lopes; Lee Juna; Jiang Wei-Wen; Baek Jin Hyen; Liu Junwei; Osada Motonobu; Moon Chul-So; Califano Joseph A; Mori Masaki; Sidransky David
DCC promoter hypermethylation in esophageal squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2008;122(11):2498-502.
2008: Chatterjee A; Chang X; Nagpal J K; Chang S; Upadhyay S; Califano J; Trink B; Sidransky D
Targeting human 8-oxoguanine DNA glycosylase to mitochondria protects cells from 2-methoxyestradiol-induced-mitochondria-dependent apoptosis.
Oncogene 2008;27(26):3710-20.
2008: Kim M S; Chang X; Yamashita K; Nagpal J K; Baek J H; Wu G; Trink B; Ratovitski E A; Mori M; Sidransky D
Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma.
Oncogene 2008;27(25):3624-34.
2008: Chatterjee Aditi; Upadhyay Sunil; Chang Xiaofei; Nagpal Jatin K; Trink Barry; Sidransky David
U-box-type ubiquitin E4 ligase, UFD2a attenuates cisplatin mediated degradation of DeltaNp63alpha.
Cell cycle (Georgetown, Tex.) 2008;7(9):1231-7.
2008: Kim Myoung Sook; Lebron Cinthia; Nagpal Jatin K; Chae Young Kwang; Chang Xiaofei; Huang Yiping; Chuang Tony; Yamashita Keishi; Trink Barry; Ratovitski Edward A; Califano Joseph A; Sidransky David
Methylation of the DFNA5 increases risk of lymph node metastasis in human breast cancer.
Biochemical and biophysical research communications 2008;370(1):38-43.
2008: Jeronimo Carmen; Monteiro Paula; Henrique Rui; Dinis-Ribeiro Mário; Costa Isabel; Costa Vera L; Filipe Luísa; Carvalho André L; Hoque Mohammad O; Pais Irene; Leal Conceição; Teixeira Manuel R; Sidransky David
Quantitative hypermethylation of a small panel of genes augments the diagnostic accuracy in fine-needle aspirate washings of breast lesions.
Breast cancer research and treatment 2008;109(1):27-34.
2008: Hoque Mohammad Obaidul; Kim Myoung Sook; Ostrow Kimberly Laskie; Liu Junwei; Wisman G Bea A; Park Hannah Lui; Poeta Maria Luana; Jeronimo Carmen; Henrique Rui; Lendvai Agnes; Schuuring Ed; Begum Shahnaz; Rosenbaum Eli; Ongenaert Maté; Yamashita Keishi; Califano Joseph; Westra William; van der Zee Ate G J; Van Criekinge Wim; Sidransky David
Genome-wide promoter analysis uncovers portions of the cancer methylome.
Cancer research 2008;68(8):2661-70.
2008: Liu Jun-Wei; Nagpal Jatin K; Jeronimo Carmen; Lee Ji Eun; Henrique Rui; Kim Myoung Sook; Ostrow Kimberly L; Yamashita Keishi; van Criekinge Vim; Wu Guojun; Moon Chu-So; Trink Barry; Sidransky David
Hypermethylation of MCAM gene is associated with advanced tumor stage in prostate cancer.
The Prostate 2008;68(4):418-26.
2008: Woo Janghee; Lee Juna; Kim Myoung Sook; Jang Se Jin; Sidransky David; Moon Chulso
The effect of aquaporin 5 overexpression on the Ras signaling pathway.
Biochemical and biophysical research communications 2008;367(2):291-8.
2008: Kim M S; Chang X; Nagpal J K; Yamashita K; Baek J H; Dasgupta S; Wu G; Osada M; Woo J-H; Westra W H; Trink B; Ratovitski E A; Moon C; Sidransky D
The N-methyl-D-aspartate receptor type 2A is frequently methylated in human colorectal carcinoma and suppresses cell growth.
Oncogene 2008;27(14):2045-54.
2008: Dasgupta Santanu; Hoque Mohammad Obaidul; Upadhyay Sunil; Sidransky David
Mitochondrial cytochrome B gene mutation promotes tumor growth in bladder cancer.
Cancer research 2008;68(3):700-6.
2008: Hoque Mohammad Obaidul; Begum Shahnaz; Brait Mariana; Jeronimo Carmen; Zahurak Marianna; Ostrow Kimberly Laskie; Rosenbaum Eli; Trock Bruce; Westra William H; Schoenberg Mark; Goodman Steven N; Sidransky David
Tissue inhibitor of metalloproteinases-3 promoter methylation is an independent prognostic factor for bladder cancer.
The Journal of urology 2008;179(2):743-7.
2008: Woo Janghee; Chae Young Kwang; Jang Se Jin; Kim Myoung Sook; Baek Jin Hyen; Park Jong Chul; Trink Barry; Ratovitski Edward; Lee Taekyul; Park Beomsoo; Park Minjoo; Kang Ji Hye; Soria Jean Charles; Lee Juna; Califano Joseph; Sidransky David; Moon Chulso
Membrane trafficking of AQP5 and cAMP dependent phosphorylation in bronchial epithelium.
Biochemical and biophysical research communications 2008;366(2):321-7.
2008: Yamashita Keishi; Kim Myoung Sook; Park Hannah Lui; Tokumaru Yutaka; Osada Motonobu; Inoue Hiroshi; Mori Masaki; Sidransky David
HOP/OB1/NECC1 promoter DNA is frequently hypermethylated and involved in tumorigenic ability in esophageal squamous cell carcinoma.
Molecular cancer research : MCR 2008;6(1):31-41.
2008: Westra William H; Taube Janis M; Poeta M L; Begum Shanaz; Sidransky David; Koch Wayne M
Inverse relationship between human papillomavirus-16 infection and disruptive p53 gene mutations in squamous cell carcinoma of the head and neck.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(2):366-9.
2008: Moon Chul-So; Agbo Eddy C; Sidransky David
Slow development impedes the uptake of diagnostics.
Nature 2008;451(7174):16.
2008: Carvalho André Lopes; Jeronimo Carmen; Kim Michael M; Henrique Rui; Zhang Zhe; Hoque Mohammad O; Chang Steve; Brait Mariana; Nayak Chetan S; Jiang Wei-Wen; Claybourne Quia; Tokumaru Yutaka; Lee Juna; Goldenberg David; Garrett-Mayer Elizabeth; Goodman Steven; Moon Chul-so; Koch Wayne; Westra William H; Sidransky David; Califano Joseph A
Evaluation of promoter hypermethylation detection in body fluids as a screening/diagnosis tool for head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):97-107.
2008: Park Jong Chul; Chae Young Kwang; Son Choon Hee; Kim Myoung Sook; Lee Juna; Ostrow Kimberly; Sidransky David; Hoque Mohammad Obaidul; Moon Chulso
Epigenetic silencing of human T (brachyury homologue) gene in non-small-cell lung cancer.
Biochemical and biophysical research communications 2008;365(2):221-6.
2008: Jakupciak John P; Maragh Samantha; Markowitz Maura E; Greenberg Alissa K; Hoque Mohammad O; Maitra Anirban; Barker Peter E; Wagner Paul D; Rom William N; Srivastava Sudhir; Sidransky David; O'Connell Catherine D
Performance of mitochondrial DNA mutations detecting early stage cancer.
BMC cancer 2008;8():285.
2008: Cui Yan; Ying Ying; van Hasselt Andrew; Ng Ka Man; Yu Jun; Zhang Qian; Jin Jie; Liu Dingxie; Rhim Johng S; Rha Sun Young; Loyo Myriam; Chan Anthony T C; Srivastava Gopesh; Tsao George S W; Sellar Grant C; Sung Joseph J Y; Sidransky David; Tao Qian
OPCML is a broad tumor suppressor for multiple carcinomas and lymphomas with frequently epigenetic inactivation.
PloS one 2008;3(8):e2990.
2008: Chae Young Kwang; Kang Sung Koo; Kim Myoung Sook; Woo Janghee; Lee Juna; Chang Steven; Kim Dong-Wook; Kim Myungshin; Park Seonyang; Kim Inho; Keam Bhumsuk; Rhee Jiyoung; Koo Nam Hee; Park Gyeongsin; Kim Soo-Hyun; Jang Se-Eun; Kweon Il-Young; Sidransky David; Moon Chulso
Human AQP5 plays a role in the progression of chronic myelogenous leukemia (CML).
PloS one 2008;3(7):e2594.
2008: Chae Young Kwang; Woo Janghee; Kim Mi-Jung; Kang Sung Koo; Kim Myoung Sook; Lee Juna; Lee Seung Koo; Gong Gyungyub; Kim Yong Hee; Soria Jean Charles; Jang Se Jin; Sidransky David; Moon Chulso
Expression of aquaporin 5 (AQP5) promotes tumor invasion in human non small cell lung cancer.
PloS one 2008;3(5):e2162.
2008: Maragh Samantha; Jakupciak John P; Wagner Paul D; Rom William N; Sidransky David; Srivastava Sudhir; O'Connell Catherine D
Multiple strand displacement amplification of mitochondrial DNA from clinical samples.
BMC medical genetics 2008;9():7.
2007: Poeta M Luana; Manola Judith; Goldwasser Meredith A; Forastiere Arlene; Benoit Nicole; Califano Joseph A; Ridge John A; Goodwin Jarrard; Kenady Daniel; Saunders John; Westra William; Sidransky David; Koch Wayne M
TP53 mutations and survival in squamous-cell carcinoma of the head and neck.
The New England journal of medicine 2007;357(25):2552-61.
2007: Couch Marion E; Ferris Robert L; Brennan Joseph A; Koch Wayne M; Jaffee Elizabeth M; Leibowitz Michael S; Nepom Gerald T; Erlich Henry A; Sidransky David
Alteration of cellular and humoral immunity by mutant p53 protein and processed mutant peptide in head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7199-206.
2007: Ball Douglas W; Jin Ning; Rosen D Marc; Dackiw Alan; Sidransky David; Xing Mingzhao; Nelkin Barry D
Selective growth inhibition in BRAF mutant thyroid cancer by the mitogen-activated protein kinase kinase 1/2 inhibitor AZD6244.
The Journal of clinical endocrinology and metabolism 2007;92(12):4712-8.
2007: Kim Myoung Sook; Yamashita Keishi; Chae Young Kwang; Tokumaru Yutaka; Chang Xiaofei; Zahurak Marianna; Osada Motonobu; Park Hannah Lui; Chuang Alice; Califano Joseph A; Sidransky David
A promoter methylation pattern in the N-methyl-D-aspartate receptor 2B gene predicts poor prognosis in esophageal squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(22 Pt 1):6658-65.
2007: Liu Jun-Wei; Kim Myoung Sook; Nagpal Jatin; Yamashita Keishi; Poeta Luana; Chang Xiaofei; Lee Juna; Park Hannah Lui; Jeronimo Carmen; Westra William H; Mori Masaki; Moon Chulso; Trink Barry; Sidransky David
Quantitative hypermethylation of NMDAR2B in human gastric cancer.
International journal of cancer. Journal international du cancer 2007;121(9):1994-2000.
2007: Henrique Rui; Ribeiro Franclim R; Fonseca Daniel; Hoque Mohammad O; Carvalho André L; Costa Vera L; Pinto Mafalda; Oliveira Jorge; Teixeira Manuel R; Sidransky David; Jerónimo Carmen
High promoter methylation levels of APC predict poor prognosis in sextant biopsies from prostate cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(20):6122-9.
2007: Nayak Chetan S; Carvalho André Lopes; Jeronimo Carmen; Henrique Rui; Kim Michael M; Hoque Mohammad O; Chang Steve; Jiang Wei-Wen; Koch Wayne; Westra William; Sidransky David; Califano Joseph
Positive correlation of tissue inhibitor of metalloproteinase-3 and death-associated protein kinase hypermethylation in head and neck squamous cell carcinoma.
The Laryngoscope 2007;117(8):1376-80.
2007: Kang Sokbom; Kim Hy-Sook; Seo Sang Soo; Park Sang-Yoon; Sidransky David; Dong Seung Myung
Inverse correlation between RASSF1A hypermethylation, KRAS and BRAF mutations in cervical adenocarcinoma.
Gynecologic oncology 2007;105(3):662-6.
2007: Zhou Shaoyu; Kachhap Sushant; Sun Wenyue; Wu Guojun; Chuang Alice; Poeta Luana; Grumbine Lawson; Mithani Suhail K; Chatterjee Aditi; Koch Wayne; Westra William H; Maitra Anirban; Glazer Chad; Carducci Michael; Sidransky David; McFate Thomas; Verma Ajay; Califano Joseph A
Frequency and phenotypic implications of mitochondrial DNA mutations in human squamous cell cancers of the head and neck.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(18):7540-5.
2007: Wu Guojun; Guo Zhongmin; Chang Xiaofei; Kim Myoung Sook; Nagpal Jatin K; Liu Junwei; Maki Joni M; Kivirikko Kari I; Ethier Stephen P; Trink Barry; Sidransky David
LOXL1 and LOXL4 are epigenetically silenced and can inhibit ras/extracellular signal-regulated kinase signaling pathway in human bladder cancer.
Cancer research 2007;67(9):4123-9.
2007: Upadhyay Sunil; Chatterjee Aditi; Trink Barry; Sommer Matthias; Ratovitski Edward; Sidransky David
TAp63gamma regulates hOGG1 and repair of oxidative damage in cancer cell lines.
Biochemical and biophysical research communications 2007;356(4):823-8.
2007: Osada Motonobu; Park Hannah Lui; Park Min Joo; Liu Jun-Wei; Wu Guojun; Trink Barry; Sidransky David
A p53-type response element in the GDF15 promoter confers high specificity for p53 activation.
Biochemical and biophysical research communications 2007;354(4):913-8.
2007: Liu Chunyan; Zhou Shaoyu; Begum Shahnaz; Sidransky David; Westra William H; Brock Malcolm; Califano Joseph A
Increased expression and activity of repair genes TDP1 and XPF in non-small cell lung cancer.
Lung cancer (Amsterdam, Netherlands) 2007;55(3):303-11.
2007: Trink Barry; Osada Motonobu; Ratovitski Edward; Sidransky David
p63 transcriptional regulation of epithelial integrity and cancer.
Cell cycle (Georgetown, Tex.) 2007;6(3):240-5.
2007: Seng T J; Low J S W; Li H; Cui Y; Goh H K; Wong M L Y; Srivastava G; Sidransky D; Califano J; Steenbergen R D M; Rha S Y; Tan J; Hsieh W-S; Ambinder R F; Lin X; Chan A T C; Tao Q
The major 8p22 tumor suppressor DLC1 is frequently silenced by methylation in both endemic and sporadic nasopharyngeal, esophageal, and cervical carcinomas, and inhibits tumor cell colony formation.
Oncogene 2007;26(6):934-44.
2007: Jiang Wei-Wen; Zahurak Marianna; Zhou Zeng-Tong; Park Hannah Lui; Guo Zhong-Min; Wu Guo-Jun; Sidransky David; Trink Barry; Califano Joseph A
Alterations of GPI transamidase subunits in head and neck squamous carcinoma.
Molecular cancer 2007;6():74.
2006: Mehta T K; Hoque M O; Ugarte R; Rahman M H; Kraus E; Montgomery R; Melancon K; Sidransky D; Rabb H
Quantitative detection of promoter hypermethylation as a biomarker of acute kidney injury during transplantation.
Transplantation proceedings 2006;38(10):3420-6.
2006: Jiang Wei-Wen; Zahurak Marianna; Goldenberg David; Milman Yelena; Park Hannah Lui; Westra William H; Koch Wayne; Sidransky David; Califano Joseph
Increased plasma DNA integrity index in head and neck cancer patients.
International journal of cancer. Journal international du cancer 2006;119(11):2673-6.
2006: Westra William H; Sidransky David
Fluorescence visualization in oral neoplasia: shedding light on an old problem.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(22):6594-7.
2006: Henrique Rui; Costa Vera Lúcia; Cerveira Nuno; Carvalho André Lopes; Hoque Mohammad Obaidul; Ribeiro Franclim Ricardo; Oliveira Jorge; Teixeira Manuel Rodrigues; Sidransky David; Jerónimo Carmen
Hypermethylation of Cyclin D2 is associated with loss of mRNA expression and tumor development in prostate cancer.
Journal of molecular medicine (Berlin, Germany) 2006;84(11):911-8.
2006: Wu Guojun; Guo Zhongmin; Chatterjee Aditi; Huang Xin; Rubin Ethel; Wu Feng; Mambo Elizabeth; Chang Xiaofei; Osada Motonobu; Sook Kim Myoung; Moon Chulso; Califano Joseph A; Ratovitski Edward A; Gollin Susanne M; Sukumar Saraswati; Sidransky David; Trink Barry
Overexpression of glycosylphosphatidylinositol (GPI) transamidase subunits phosphatidylinositol glycan class T and/or GPI anchor attachment 1 induces tumorigenesis and contributes to invasion in human breast cancer.
Cancer research 2006;66(20):9829-36.
2006: Singh Anju; Misra Vikas; Thimmulappa Rajesh K; Lee Hannah; Ames Stephen; Hoque Mohammad O; Herman James G; Baylin Stephen B; Sidransky David; Gabrielson Edward; Brock Malcolm V; Biswal Shyam
Dysfunctional KEAP1-NRF2 interaction in non-small-cell lung cancer.
PLoS medicine 2006;3(10):e420.
2006: Carvalho André Lopes; Chuang Alice; Jiang Wei-Wen; Lee Juna; Begum Shahnaz; Poeta Luana; Zhao Ming; Jerónimo Carmen; Henrique Rui; Nayak Chetan S; Park Hannah L; Brait Mariana R O; Liu Chunyan; Zhou Shaoyu; Koch Wayne; Fazio Vito Michele; Ratovitski Edward; Trink Barry; Westra William; Sidransky David; Moon Chul-so; Califano Joseph A
Deleted in colorectal cancer is a putative conditional tumor-suppressor gene inactivated by promoter hypermethylation in head and neck squamous cell carcinoma.
Cancer research 2006;66(19):9401-7.
2006: Wisman G Bea A; Nijhuis Esther R; Hoque Mohammad O; Reesink-Peters Nathalie; Koning Alice J; Volders Haukeline H; Buikema Henk J; Boezen H Marike; Hollema Harry; Schuuring Ed; Sidransky David; van der Zee Ate G J
Assessment of gene promoter hypermethylation for detection of cervical neoplasia.
International journal of cancer. Journal international du cancer 2006;119(8):1908-14.
2006: Sommer Matthias; Poliak Nina; Upadhyay Sunil; Ratovitski Edward; Nelkin Barry D; Donehower Lawrence A; Sidransky David
DeltaNp63alpha overexpression induces downregulation of Sirt1 and an accelerated aging phenotype in the mouse.
Cell cycle (Georgetown, Tex.) 2006;5(17):2005-11.
2006: Zhou Shaoyu; Kassauei Keyaunoosh; Cutler David J; Kennedy Giulia C; Sidransky David; Maitra Anirban; Califano Joseph
An oligonucleotide microarray for high-throughput sequencing of the mitochondrial genome.
The Journal of molecular diagnostics : JMD 2006;8(4):476-82.
2006: Hoque Mohammad O; Feng Qinghua; Toure Papa; Dem Amadou; Critchlow Cathy W; Hawes Stephen E; Wood Troy; Jeronimo Carmen; Rosenbaum Eli; Stern Joshua; Yu Mujun; Trink Barry; Kiviat Nancy B; Sidransky David
Detection of aberrant methylation of four genes in plasma DNA for the detection of breast cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2006;24(26):4262-9.
2006: Kang Sokbom; Lee Jae Myun; Jeon Eun-Sook; Lee Sun; Kim Hogeun; Kim Hy-Sook; Seo Sang-Soo; Park Sang-Yoon; Sidransky David; Dong Seung Myung
RASSF1A hypermethylation and its inverse correlation with BRAF and/or KRAS mutations in MSI-associated endometrial carcinoma.
International journal of cancer. Journal international du cancer 2006;119(6):1316-21.
2006: Upadhyay Sunil; Liu Chunyan; Chatterjee Aditi; Hoque Mohammad O; Kim Myoung Sook; Engles James; Westra William; Trink Barry; Ratovitski Edward; Sidransky David
LKB1/STK11 suppresses cyclooxygenase-2 induction and cellular invasion through PEA3 in lung cancer.
Cancer research 2006;66(16):7870-9.
2006: Chatterjee A; Mambo E; Sidransky D
Mitochondrial DNA mutations in human cancer.
Oncogene 2006;25(34):4663-74.
2006: Hoque Mohammad Obaidul; Begum Shahnaz; Topaloglu Ozlem; Chatterjee Aditi; Rosenbaum Eli; Van Criekinge Wim; Westra William H; Schoenberg Mark; Zahurak Marianna; Goodman Steven N; Sidransky David
Quantitation of promoter methylation of multiple genes in urine DNA and bladder cancer detection.
Journal of the National Cancer Institute 2006;98(14):996-1004.
2006: Yamashita Keishi; Park Hannah Lui; Kim Myoung Sook; Osada Motonobu; Tokumaru Yutaka; Inoue Hiroshi; Mori Masaki; Sidransky David
PGP9.5 methylation in diffuse-type gastric cancer.
Cancer research 2006;66(7):3921-7.
2006: Kim Myoung Sook; Yamashita Keishi; Baek Jin Hyen; Park Hannah Lui; Carvalho Andre Lopes; Osada Motonobu; Hoque Mohammad Obaidul; Upadhyay Sunil; Mori Masaki; Moon Chulso; Sidransky David
N-methyl-D-aspartate receptor type 2B is epigenetically inactivated and exhibits tumor-suppressive activity in human esophageal cancer.
Cancer research 2006;66(7):3409-18.
2006: Hoque Mohammad Obaidul; Soria Jean-Charles; Woo Janghee; Lee Taekyeol; Lee Juna; Jang Se Jin; Upadhyay Sunil; Trink Barry; Monitto Constance; Desmaze Chantal; Mao Li; Sidransky David; Moon Chulso
Aquaporin 1 is overexpressed in lung cancer and stimulates NIH-3T3 cell proliferation and anchorage-independent growth.
The American journal of pathology 2006;168(4):1345-53.
2006: Jiang Wei-Wen; Rosenbaum Eli; Mambo Elizabeth; Zahurak Marianna; Masayesva Brett; Carvalho Andre Lopes; Zhou Shaoyu; Westra William H; Alberg Anthony J; Sidransky David; Koch Wayne; Califano Joseph A
Decreased mitochondrial DNA content in posttreatment salivary rinses from head and neck cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(5):1564-9.
2006: Kim Michael M; Glazer Chad A; Mambo Elizabeth; Chatterjee Aditi; Zhao Ming; Sidransky David; Califano Joseph A
Head and neck cancer cell lines exhibit differential mitochondrial repair deficiency in response to 4NQO.
Oral oncology 2006;42(2):201-7.
2006: Henrique Rui; Jerónimo Carmen; Teixeira Manuel R; Hoque Mohammad O; Carvalho André L; Pais Irene; Ribeiro Franclim R; Oliveira Jorge; Lopes Carlos; Sidransky David
Epigenetic heterogeneity of high-grade prostatic intraepithelial neoplasia: clues for clonal progression in prostate carcinogenesis.
Molecular cancer research : MCR 2006;4(1):1-8.
2006: Masayesva Brett G; Mambo Elizabeth; Taylor Rodney J; Goloubeva Olga G; Zhou Shaoyu; Cohen Yoram; Minhas Khalid; Koch Wayne; Sciubba James; Alberg Anthony J; Sidransky David; Califano Joseph
Mitochondrial DNA content increase in response to cigarette smoking.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2006;15(1):19-24.
2006: Ratovitski Edward; Trink Barry; Sidransky David
p63 and p73: teammates or adversaries?
Cancer cell 2006;9(1):1-2.
2006: Osada Motonobu; Park Hannah Lui; Nagakawa Yuichi; Begum Shahnaz; Yamashita Keishi; Wu Guojun; Kim Myoung Sook; Trink Barry; Sidransky David
A novel response element confers p63- and p73-specific activation of the WNT4 promoter.
Biochemical and biophysical research communications 2006;339(4):1120-8.
2006: Chatterjee Aditi; Mambo Elizabeth; Osada Motonobu; Upadhyay Sunil; Sidransky David
The effect of p53-RNAi and p53 knockout on human 8-oxoguanine DNA glycosylase (hOgg1) activity.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(1):112-4.
2006: Hu Shuiying; Ewertz Marge; Tufano Ralph P; Brait Mariana; Carvalho Andre Lopes; Liu Dingxie; Tufaro Anthony P; Basaria Shehzad; Cooper David S; Sidransky David; Ladenson Paul W; Xing Mingzhao
Detection of serum deoxyribonucleic acid methylation markers: a novel diagnostic tool for thyroid cancer.
The Journal of clinical endocrinology and metabolism 2006;91(1):98-104.
2006: Sui Guoping; Zhou Shaoyu; Wang Jean; Canto Marcia; Lee Edward E; Eshleman James R; Montgomery Elizabeth A; Sidransky David; Califano Joseph A; Maitra Anirban
Mitochondrial DNA mutations in preneoplastic lesions of the gastrointestinal tract: a biomarker for the early detection of cancer.
Molecular cancer 2006;5():73.
2006: Chatterjee Aditi; Mambo Elizabeth; Zhang Yonggang; Deweese Theodore; Sidransky David
Targeting of mutant hogg1 in mammalian mitochondria and nucleus: effect on cellular survival upon oxidative stress.
BMC cancer 2006;6():235.
2005: Rosenbaum Eli; Hoque Mohammad Obaidul; Cohen Yoram; Zahurak Marianna; Eisenberger Mario A; Epstein Jonathan I; Partin Alan W; Sidransky David
Promoter hypermethylation as an independent prognostic factor for relapse in patients with prostate cancer following radical prostatectomy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(23):8321-5.
2005: Xing Mingzhao; Westra William H; Tufano Ralph P; Cohen Yoram; Rosenbaum Eli; Rhoden Kerry J; Carson Kathryn A; Vasko Vasily; Larin Alexandr; Tallini Giovanni; Tolaney Sara; Holt Elizabeth H; Hui Pei; Umbricht Christopher B; Basaria Shehzad; Ewertz Marge; Tufaro Anthony P; Califano Joseph A; Ringel Matthew D; Zeiger Martha A; Sidransky David; Ladenson Paul W
BRAF mutation predicts a poorer clinical prognosis for papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism 2005;90(12):6373-9.
2005: Zhao Ming; Rosenbaum Eli; Carvalho Andre Lopes; Koch Wayne; Jiang Weiwen; Sidransky David; Califano Joseph
Feasibility of quantitative PCR-based saliva rinse screening of HPV for head and neck cancer.
International journal of cancer. Journal international du cancer 2005;117(4):605-10.
2005: Zangen Rachel; Ratovitski Edward; Sidransky David
DeltaNp63alpha levels correlate with clinical tumor response to cisplatin.
Cell cycle (Georgetown, Tex.) 2005;4(10):1313-5.
2005: Mambo Elizabeth; Chatterjee Aditi; Xing Mingzhao; Tallini Giovanni; Haugen Bryan R; Yeung Sai-Ching J; Sukumar Saraswati; Sidransky David
Tumor-specific changes in mtDNA content in human cancer.
International journal of cancer. Journal international du cancer 2005;116(6):920-4.
2005: Hoque Mohammad Obaidul; Topaloglu Ozlem; Begum Shahnaz; Henrique Rui; Rosenbaum Eli; Van Criekinge Wim; Westra William H; Sidransky David
Quantitative methylation-specific polymerase chain reaction gene patterns in urine sediment distinguish prostate cancer patients from control subjects.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(27):6569-75.
2005: Goldenberg-Cohen Nitza; Cohen Yoram; Rosenbaum Eli; Herscovici Zvi; Chowers Itay; Weinberger Dov; Pe'er Jacob; Sidransky David
T1799A BRAF mutations in conjunctival melanocytic lesions.
Investigative ophthalmology & visual science 2005;46(9):3027-30.
2005: Wu Guojun; Mambo Elizabeth; Guo Zhongmin; Hu Shuiying; Huang Xin; Gollin Susanne M; Trink Barry; Ladenson Paul W; Sidransky David; Xing Mingzhao
Uncommon mutation, but common amplifications, of the PIK3CA gene in thyroid tumors.
The Journal of clinical endocrinology and metabolism 2005;90(8):4688-93.
2005: Osada Motonobu; Park Hannah Lui; Nagakawa Yuichi; Yamashita Keishi; Fomenkov Alexey; Kim Myoung Sook; Wu Guojun; Nomoto Shuji; Trink Barry; Sidransky David
Differential recognition of response elements determines target gene specificity for p53 and p63.
Molecular and cellular biology 2005;25(14):6077-89.
2005: Osada Motonobu; Nagakawa Yuichi; Park Hannah Lui; Yamashita Keishi; Wu Guojun; Kim Myoung Sook; Fomenkov Alexey; Trink Barry; Sidransky David
p63-specific activation of the BPAG-1e promoter.
The Journal of investigative dermatology 2005;125(1):52-60.
2005: Rosenbaum Eli; Hosler Gregory; Zahurak Marianna; Cohen Yoram; Sidransky David; Westra William H
Mutational activation of BRAF is not a major event in sporadic childhood papillary thyroid carcinoma.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(7):898-902.
2005: Hoque M O; Rosenbaum E; Westra W H; Xing M; Ladenson P; Zeiger M A; Sidransky D; Umbricht C B
Quantitative assessment of promoter methylation profiles in thyroid neoplasms.
The Journal of clinical endocrinology and metabolism 2005;90(7):4011-8.
2005: Mandelker Diana L; Yamashita Keishi; Tokumaru Yutaka; Mimori Koshi; Howard David L; Tanaka Yoichi; Carvalho Andre Lopes; Jiang Wei-Wen; Park Hannah Lui; Kim Myoung Sook; Osada Motonobu; Mori Masaki; Sidransky David
PGP9.5 promoter methylation is an independent prognostic factor for esophageal squamous cell carcinoma.
Cancer research 2005;65(11):4963-8.
2005: Mambo Elizabeth; Chatterjee Aditi; de Souza-Pinto Nadja C; Mayard Sabine; Hogue Barbara A; Hoque Mohammad O; Dizdaroglu Miral; Bohr Vilhelm A; Sidransky David
Oxidized guanine lesions and hOgg1 activity in lung cancer.
Oncogene 2005;24(28):4496-508.
2005: Henrique Rui; Jerónimo Carmen; Hoque Mohammad O; Nomoto Shuji; Carvalho André L; Costa Vera L; Oliveira Jorge; Teixeira Manuel R; Lopes Carlos; Sidransky David
MT1G hypermethylation is associated with higher tumor stage in prostate cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(5):1274-8.
2005: Kim Myoung Sook; Baek Jin Hyen; Chakravarty Devulapalli; Sidransky David; Carrier France
Sensitization to UV-induced apoptosis by the histone deacetylase inhibitor trichostatin A (TSA).
Experimental cell research 2005;306(1):94-102.
2005: Jakupciak John P; Wang Wendy; Markowitz Maura E; Ally Delphine; Coble Michael; Srivastava Sudhir; Maitra Anirban; Barker Peter E; Sidransky David; O'Connell Catherine D
Mitochondrial DNA as a cancer biomarker.
The Journal of molecular diagnostics : JMD 2005;7(2):258-67.
2005: Benoit Nicole E; Goldenberg David; Deng Shirley X; Rosenbaum Eli; Cohen Yoram; Califano Joseph A; Shackelford William H; Wang Xiao B; Sidransky David
Colorimetric approach to high-throughput mutation analysis.
BioTechniques 2005;38(4):635-9.
2005: Jiang Wei-Wen; Masayesva Brett; Zahurak Marianna; Carvalho Andre Lopes; Rosenbaum Eli; Mambo Elizabeth; Zhou Shaoyu; Minhas Khalid; Benoit Nicole; Westra William H; Alberg Anthony; Sidransky David; Koch Wayne; Califano Joseph
Increased mitochondrial DNA content in saliva associated with head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2486-91.
2005: Russo Andrea L; Thiagalingam Arunthathi; Pan Hongjie; Califano Joseph; Cheng Kuang-hung; Ponte Jose F; Chinnappan Dharmaraj; Nemani Pratima; Sidransky David; Thiagalingam Sam
Differential DNA hypermethylation of critical genes mediates the stage-specific tobacco smoke-induced neoplastic progression of lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2466-70.
2005: Henrique Rui; Jerónimo Carmen; Hoque Mohammad O; Carvalho André L; Oliveira Jorge; Teixeira Manuel R; Lopes Carlos; Sidransky David
Frequent 14-3-3 sigma promoter methylation in benign and malignant prostate lesions.
DNA and cell biology 2005;24(4):264-9.
2005: Pan Hongjie; Califano Joseph; Ponte Jose F; Russo Andrea L; Cheng Kuang-hung; Thiagalingam Arunthathi; Nemani Pratima; Sidransky David; Thiagalingam Sam
Loss of heterozygosity patterns provide fingerprints for genetic heterogeneity in multistep cancer progression of tobacco smoke-induced non-small cell lung cancer.
Cancer research 2005;65(5):1664-9.
2005: Masasyesva Brett G; Tong Betty C; Brock Malcolm V; Pilkington Thomas; Goldenberg David; Sidransky David; Harden Susan; Westra William H; Califano Joseph
Molecular margin analysis predicts local recurrence after sublobar resection of lung cancer.
International journal of cancer. Journal international du cancer 2005;113(6):1022-5.
2005: Wu Guojun; Osada Motonobu; Guo Zhongmin; Fomenkov Alexey; Begum Shahnaz; Zhao Ming; Upadhyay Sunil; Xing Mingzhao; Wu Feng; Moon Chulso; Westra William H; Koch Wayne M; Mantovani Roberto; Califano Joseph A; Ratovitski Edward; Sidransky David; Trink Barry
DeltaNp63alpha up-regulates the Hsp70 gene in human cancer.
Cancer research 2005;65(3):758-66.
2005: Davison Jon M; Rosenbaum Eli; Barrett Terry L; Goldenberg David; Hoque Mohammad O; Sidransky David; Westra William H
Absence of V599E BRAF mutations in desmoplastic melanomas.
Cancer 2005;103(4):788-92.
2005: Costanzi John; Sidransky David; Navon Ami; Goldsweig Howard
Ribonucleases as a novel pro-apoptotic anticancer strategy: review of the preclinical and clinical data for ranpirnase.
Cancer investigation 2005;23(7):643-50.
2005: Wu Guojun; Xing Mingzhao; Mambo Elizabeth; Huang Xin; Liu Junwei; Guo Zhongmin; Chatterjee Aditi; Goldenberg David; Gollin Susanne M; Sukumar Saraswati; Trink Barry; Sidransky David
Somatic mutation and gain of copy number of PIK3CA in human breast cancer.
Breast cancer research : BCR 2005;7(5):R609-16.
2004: Xiao Yan; Monitto Constance L; Minhas Khalid M; Sidransky David
Lactoferrin down-regulates G1 cyclin-dependent kinases during growth arrest of head and neck cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8683-6.
2004: Jerónimo Carmen; Henrique Rui; Hoque Mohammad O; Mambo Elizabeth; Ribeiro Franclim R; Varzim Graça; Oliveira Jorge; Teixeira Manuel R; Lopes Carlos; Sidransky David
A quantitative promoter methylation profile of prostate cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(24):8472-8.
2004: Goldenberg David; Lee Juna; Koch Wayne M; Kim Michael M; Trink Barry; Sidransky David; Moon Chul-So
Habitual risk factors for head and neck cancer.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 2004;131(6):986-93.
2004: Huang Yi-Ping; Wu Guojun; Guo Zhongmin; Osada Motonobu; Fomenkov Tanya; Park Hannah Lui; Trink Barry; Sidransky David; Fomenkov Alexey; Ratovitski Edward A
Altered sumoylation of p63alpha contributes to the split-hand/foot malformation phenotype.
Cell cycle (Georgetown, Tex.) 2004;3(12):1587-96.
2004: Begum Shahnaz; Rosenbaum Eli; Henrique Rui; Cohen Yoram; Sidransky David; Westra William H
BRAF mutations in anaplastic thyroid carcinoma: implications for tumor origin, diagnosis and treatment.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(11):1359-63.
2004: Goldenberg David; Rosenbaum Eli; Argani Pedram; Wistuba Ignacio I; Sidransky David; Thuluvath Paul J; Hidalgo Manuel; Califano Joseph; Maitra Anirban
The V599E BRAF mutation is uncommon in biliary tract cancers.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2004;17(11):1386-91.
2004: Fomenkov Alexey; Zangen Rachel; Huang Yi-Ping; Osada Motonobu; Guo Zhongmin; Fomenkov Tanya; Trink Barry; Sidransky David; Ratovitski Edward A
RACK1 and stratifin target DeltaNp63alpha for a proteasome degradation in head and neck squamous cell carcinoma cells upon DNA damage.
Cell cycle (Georgetown, Tex.) 2004;3(10):1285-95.
2004: Andrews Genevieve A; Xi Sichuan; Pomerantz Rebecca G; Lin Charles J; Gooding William E; Wentzel Abbey L; Wu Li; Sidransky David; Grandis Jennifer Rubin
Mutation of p53 in head and neck squamous cell carcinoma correlates with Bcl-2 expression and increased susceptibility to cisplatin-induced apoptosis.
Head & neck 2004;26(10):870-7.
2004: Medina Pedro P; Carretero Julian; Fraga Mario F; Esteller Manel; Sidransky David; Sanchez-Cespedes Montserrat
Genetic and epigenetic screening for gene alterations of the chromatin-remodeling factor, SMARCA4/BRG1, in lung tumors.
Genes, chromosomes & cancer 2004;41(2):170-7.
2004: Monitto Constance L; Dong Seung-Myung; Jen Jin; Sidransky David
Characterization of a human homologue of proteolysis-inducing factor and its role in cancer cachexia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(17):5862-9.
2004: Tokumaru Yutaka; Yamashita Keishi; Osada Motonobu; Nomoto Shuji; Sun Dong-Il; Xiao Yan; Hoque Mohammad Obaidul; Westra William H; Califano Joseph A; Sidransky David
Inverse correlation between cyclin A1 hypermethylation and p53 mutation in head and neck cancer identified by reversal of epigenetic silencing.
Cancer research 2004;64(17):5982-7.
2004: Tokumaru Yutaka; Harden Susan V; Sun Dong-Il; Yamashita Keishi; Epstein Jonathan I; Sidransky David
Optimal use of a panel of methylation markers with GSTP1 hypermethylation in the diagnosis of prostate adenocarcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(16):5518-22.
2004: Hoque Mohammad Obaidul; Begum Shahnaz; Topaloglu Ozlem; Jeronimo Carmen; Mambo Elizabeth; Westra William H; Califano J A; Sidransky David
Quantitative detection of promoter hypermethylation of multiple genes in the tumor, urine, and serum DNA of patients with renal cancer.
Cancer research 2004;64(15):5511-7.
2004: Nawroz-Danish Homaira; Eisenberger Claus F; Yoo George H; Wu Li; Koch Wayne; Black Carri; Ensley John F; Wei Wei-Zen; Sidransky David
Microsatellite analysis of serum DNA in patients with head and neck cancer.
International journal of cancer. Journal international du cancer 2004;111(1):96-100.
2004: Jerónimo Carmen; Henrique Rui; Hoque Mohammad O; Ribeiro Franclim R; Oliveira Jorge; Fonseca Daniel; Teixeira Manuel R; Lopes Carlos; Sidransky David
Quantitative RARbeta2 hypermethylation: a promising prostate cancer marker.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(12 Pt 1):4010-4.
2004: Xing Mingzhao; Tufano Ralph P; Tufaro Anthony P; Basaria Shehzad; Ewertz Marge; Rosenbaum Eli; Byrne Patrick J; Wang James; Sidransky David; Ladenson Paul W
Detection of BRAF mutation on fine needle aspiration biopsy specimens: a new diagnostic tool for papillary thyroid cancer.
The Journal of clinical endocrinology and metabolism 2004;89(6):2867-72.
2004: Goldenberg David; Benoit Nicole E; Begum Shahnaz; Westra William H; Cohen Yoram; Koch Wayne M; Sidransky David; Califano Joseph A
Epstein-Barr virus in head and neck cancer assessed by quantitative polymerase chain reaction.
The Laryngoscope 2004;114(6):1027-31.
2004: Masayesva Brett G; Ha Patrick; Garrett-Mayer Elizabeth; Pilkington Thomas; Mao Rong; Pevsner Jonathan; Speed Traci; Benoit Nicole; Moon Chul-So; Sidransky David; Westra William H; Califano Joseph
Gene expression alterations over large chromosomal regions in cancers include multiple genes unrelated to malignant progression.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(23):8715-20.
2004: Zhou Ming; Tokumaru Yutaka; Sidransky David; Epstein Jonathan I
Quantitative GSTP1 methylation levels correlate with Gleason grade and tumor volume in prostate needle biopsies.
The Journal of urology 2004;171(6 Pt 1):2195-8.
2004: Reesink-Peters Nathalie; Wisman G Bea A; Jéronimo Carmen; Tokumaru C Yutaka; Cohen Yoram; Dong Seung Myung; Klip Harrie G; Buikema Henk J; Suurmeijer Albert J H; Hollema Harrie; Boezen H Marieke; Sidransky David; van der Zee Ate G J
Detecting cervical cancer by quantitative promoter hypermethylation assay on cervical scrapings: a feasibility study.
Molecular cancer research : MCR 2004;2(5):289-95.
2004: Cohen Yoram; Rosenbaum Eli; Begum Shahnaz; Goldenberg David; Esche Clemens; Lavie Ofer; Sidransky David; Westra William H
Exon 15 BRAF mutations are uncommon in melanomas arising in nonsun-exposed sites.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(10):3444-7.
2004: Maitra Anirban; Cohen Yoram; Gillespie Susannah E D; Mambo Elizabeth; Fukushima Noriyoshi; Hoque Mohammad O; Shah Nila; Goggins Michael; Califano Joseph; Sidransky David; Chakravarti Aravinda
The Human MitoChip: a high-throughput sequencing microarray for mitochondrial mutation detection.
Genome research 2004;14(5):812-9.
2004: Cohen Yoram; Rosenbaum Eli; Clark Douglas P; Zeiger Martha A; Umbricht Christopher B; Tufano Ralph P; Sidransky David; Westra William H
Mutational analysis of BRAF in fine needle aspiration biopsies of the thyroid: a potential application for the preoperative assessment of thyroid nodules.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2761-5.
2004: Koch Wayne; Sidransky David
Molecular markers of radiation effectiveness in head and neck squamous cell carcinoma.
Seminars in radiation oncology 2004;14(2):130-8.
2004: Harden Susan V; Thomas David C; Benoit Nicole; Minhas Khalid; Westra William H; Califano Joseph A; Koch Wayne; Sidransky David
Real-time gap ligase chain reaction: a rapid semiquantitative assay for detecting p53 mutation at low levels in surgical margins and lymph nodes from resected lung and head and neck tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2379-85.
2004: Topaloglu Ozlem; Hoque Mohammad Obaidul; Tokumaru Yutaka; Lee Juna; Ratovitski Edward; Sidransky David; Moon Chul-so
Detection of promoter hypermethylation of multiple genes in the tumor and bronchoalveolar lavage of patients with lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2284-8.
2004: Tong Betty C; Dhir Karan; Ha Patrick K; Westra William H; Alter Blanche P; Sidransky David; Koch Wayne M; Califano Joseph A
Use of single nucleotide polymorphism arrays to identify a novel region of loss on chromosome 6q in squamous cell carcinomas of the oral cavity.
Head & neck 2004;26(4):345-52.
2004: Guo Zhongmin; Linn Jürgen F; Wu Guojun; Anzick Sarah L; Eisenberger Claus F; Halachmi Sarel; Cohen Yoram; Fomenkov Alexey; Hoque Mohammad Obaidul; Okami Kenji; Steiner Gabriel; Engles James M; Osada Motonabu; Moon Chulso; Ratovitski Edward; Trent Jeffrey M; Meltzer Paul S; Westra William H; Kiemeney Lambertus A; Schoenberg Mark P; Sidransky David; Trink Barry
CDC91L1 (PIG-U) is a newly discovered oncogene in human bladder cancer.
Nature medicine 2004;10(4):374-81.
2004: Xing M; Vasko V; Tallini G; Larin A; Wu Gujun; Udelsman R; Ringel M D; Ladenson P W; Sidransky D
BRAF T1796A transversion mutation in various thyroid neoplasms.
The Journal of clinical endocrinology and metabolism 2004;89(3):1365-8.
2004: Isaacs Claudine; Cavalli Luciane R; Cohen Yoram; Pennanen Marie; Shankar Lalita K; Freedman Matthew; Singh Baljit; Liu Minetta; Gallagher Ann; Rone Janice D; Dickson Robert B; Sidransky David; Haddad Bassem R
Detection of LOH and mitochondrial DNA alterations in ductal lavage and nipple aspirate fluids from hngh-risk patients.
Breast cancer research and treatment 2004;84(2):99-105.
2004: Xing Mingzhao; Cohen Yoram; Mambo Elizabeth; Tallini Giovanni; Udelsman Robert; Ladenson Paul W; Sidransky David
Early occurrence of RASSF1A hypermethylation and its mutual exclusion with BRAF mutation in thyroid tumorigenesis.
Cancer research 2004;64(5):1664-8.
2004: Moon Chulso; Rousseau Raphael; Soria Jean-Charles; Hoque Mohammad Obaidul; Lee Juna; Jang Se Jin; Trink Barry; Sidransky David; Mao Li
Aquaporin expression in human lymphocytes and dendritic cells.
American journal of hematology 2004;75(3):128-33.
2004: Goldenberg David; Harden Susan; Masayesva Brett G; Ha Patrick; Benoit Nicole; Westra William H; Koch Wayne M; Sidransky David; Califano Joseph A
Intraoperative molecular margin analysis in head and neck cancer.
Archives of otolaryngology--head & neck surgery 2004;130(1):39-44.
2003: Parrella Paola; Fazio Vito M; Gallo Antonietta P; Sidransky David; Merbs Shannath L
Fine mapping of chromosome 3 in uveal melanoma: identification of a minimal region of deletion on chromosomal arm 3p25.1-p25.2.
Cancer research 2003;63(23):8507-10.
2003: Reddy Ashok N; Jiang Wei W; Kim Michael; Benoit Nicole; Taylor Rodney; Clinger John; Sidransky David; Califano Joseph A
Death-associated protein kinase promoter hypermethylation in normal human lymphocytes.
Cancer research 2003;63(22):7694-8.
2003: Sidransky David; Irizarry Rafael; Califano Joseph A; Li Xianbin; Ren Hening; Benoit Nicole; Mao Li
Serum protein MALDI profiling to distinguish upper aerodigestive tract cancer patients from control subjects.
Journal of the National Cancer Institute 2003;95(22):1711-7.
2003: Harden Susan V; Sanderson Harriette; Goodman Steven N; Partin Alan A W; Walsh Patrick C; Epstein Jonathan I; Sidransky David
Quantitative GSTP1 methylation and the detection of prostate adenocarcinoma in sextant biopsies.
Journal of the National Cancer Institute 2003;95(21):1634-7.
2003: Yamashita Keishi; Mimori Koshi; Inoue Hiroshi; Mori Masaki; Sidransky David
A tumor-suppressive role for trypsin in human cancer progression.
Cancer research 2003;63(20):6575-8.
2003: Verma Mukesh; Kagan Jacob; Sidransky David; Srivastava Sudhir
Proteomic analysis of cancer-cell mitochondria.
Nature reviews. Cancer 2003;3(10):789-95.
2003: Moon Chulso; Soria Jean-Charles; Jang Se Jin; Lee Juna; Obaidul Hoque Mohammad; Sibony Mathilde; Trink Barry; Chang Yoon Soo; Sidransky David; Mao Li
Involvement of aquaporins in colorectal carcinogenesis.
Oncogene 2003;22(43):6699-703.
2003: Tokumaru Yutaka; Nomoto Shuji; Jerónimo Carmen; Henrique Rui; Harden Susan; Trink Barry; Sidransky David
Biallelic inactivation of the RIZ1 gene in human gastric cancer.
Oncogene 2003;22(44):6954-8.
2003: Minhas Khalid M; Singh Bhuvanesh; Jiang Wei-Wen; Sidransky David; Califano Joseph A
Spindle assembly checkpoint defects and chromosomal instability in head and neck squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2003;107(1):46-52.
2003: Hoque Mohammad Obaidul; Lee Juna; Begum Shahnaz; Yamashita Keishi; Engles James M; Schoenberg Mark; Westra William H; Sidransky David
High-throughput molecular analysis of urine sediment for the detection of bladder cancer by high-density single-nucleotide polymorphism array.
Cancer research 2003;63(18):5723-6.
2003: Dong Seung Myung; Sun Dong-Il; Benoit Nicole E; Kuzmin Igor; Lerman Michael I; Sidransky David
Epigenetic inactivation of RASSF1A in head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 1):3635-40.
2003: Hoque Mohammad Obaidul; Begum Shahnaz; Sommer Matthias; Lee Taekyeol; Trink Barry; Ratovitski Edward; Sidransky David
PUMA in head and neck cancer.
Cancer letters 2003;199(1):75-81.
2003: Medina Pedro P; Ahrendt Steven A; Pollan Marina; Fernandez Paloma; Sidransky David; Sanchez-Cespedes Montserrat
Screening of homologous recombination gene polymorphisms in lung cancer patients reveals an association of the NBS1-185Gln variant and p53 gene mutations.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2003;12(8):699-704.
2003: Ha Patrick K; Benoit Nicole E; Yochem Robert; Sciubba James; Zahurak Marianna; Sidransky David; Pevsner Jonathan; Westra William H; Califano Joseph
A transcriptional progression model for head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):3058-64.
2003: Ghaffar Hassan; Sahin Fikret; Sanchez-Cepedes Montserrat; Su Gloria H; Zahurak Marianna; Sidransky David; Westra William H
LKB1 protein expression in the evolution of glandular neoplasia of the lung.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):2998-3003.
2003: Cohen Yoram; Singer Gad; Lavie Ofer; Dong Seung Myung; Beller Uziel; Sidransky David
The RASSF1A tumor suppressor gene is commonly inactivated in adenocarcinoma of the uterine cervix.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(8):2981-4.
2003: Parrella Paola; Zangen Rachel; Sidransky David; Nicol Theresa
Molecular analysis of peritoneal fluid in ovarian cancer patients.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2003;16(7):636-40.
2003: Ahrendt Steven A; Hu Yingchuan; Buta Martin; McDermott Michael P; Benoit Nicole; Yang Stephen C; Wu Li; Sidransky David
p53 mutations and survival in stage I non-small-cell lung cancer: results of a prospective study.
Journal of the National Cancer Institute 2003;95(13):961-70.
2003: Cohen Yoram; Goldenberg-Cohen Nitza; Parrella Paola; Chowers Itay; Merbs Shannath L; Pe'er Jacob; Sidransky David
Lack of BRAF mutation in primary uveal melanoma.
Investigative ophthalmology & visual science 2003;44(7):2876-8.
2003: Tokumaru Yutaka; Sun Dong-Il; Nomoto Shuji; Yamashita Keishi; Sidransky David
Re: Is TIG1 a new tumor suppressor in prostate cancer?
Journal of the National Cancer Institute 2003;95(12):919-20.
2003: Fomenkov Alexey; Huang Yi-Ping; Topaloglu Ozlem; Brechman Anna; Osada Motonobo; Fomenkova Tanya; Yuriditsky Eugene; Trink Barry; Sidransky David; Ratovitski Edward
P63 alpha mutations lead to aberrant splicing of keratinocyte growth factor receptor in the Hay-Wells syndrome.
The Journal of biological chemistry 2003;278(26):23906-14.
2003: Wu Guojun; Nomoto Shuji; Hoque Mohammad Obaidul; Dracheva Tatiana; Osada Motonabu; Lee Chyi-Chia Richard; Dong Seung Myung; Guo Zhongmin; Benoit Nicole; Cohen Yoram; Rechthand Peggy; Califano Joseph; Moon Chul-So; Ratovitski Edward; Jen Jin; Sidransky David; Trink Barry
DeltaNp63alpha and TAp63alpha regulate transcription of genes with distinct biological functions in cancer and development.
Cancer research 2003;63(10):2351-7.
2003: Xing Mingzhao; Usadel Henning; Cohen Yoram; Tokumaru Yutaka; Guo Zhongmin; Westra William B; Tong Betty C; Tallini Giovanni; Udelsman Robert; Califano Joseph A; Ladenson Paul W; Sidransky David
Methylation of the thyroid-stimulating hormone receptor gene in epithelial thyroid tumors: a marker of malignancy and a cause of gene silencing.
Cancer research 2003;63(9):2316-21.
2003: Xing Mingzhao; Tokumaru Yutaka; Wu Guojun; Westra William B; Ladenson Paul W; Sidransky David
Hypermethylation of the Pendred syndrome gene SLC26A4 is an early event in thyroid tumorigenesis.
Cancer research 2003;63(9):2312-5.
2003: Hoque Mohammad Obaidul; Lee Chyi-Chia R; Cairns Paul; Schoenberg Mark; Sidransky David
Genome-wide genetic characterization of bladder cancer: a comparison of high-density single-nucleotide polymorphism arrays and PCR-based microsatellite analysis.
Cancer research 2003;63(9):2216-22.
2003: Cohen Yoram; Xing Mingzhao; Mambo Elizabeth; Guo Zhongmin; Wu Guogun; Trink Barry; Beller Uziel; Westra William H; Ladenson Paul W; Sidransky David
BRAF mutation in papillary thyroid carcinoma.
Journal of the National Cancer Institute 2003;95(8):625-7.
2003: Harden Susan V; Tokumaru Yutaka; Westra William H; Goodman Steven; Ahrendt Steven A; Yang Stephen C; Sidransky David
Gene promoter hypermethylation in tumors and lymph nodes of stage I lung cancer patients.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(4):1370-5.
2003: Singer Gad; Oldt Robert; Cohen Yoram; Wang Brant G; Sidransky David; Kurman Robert J; Shih Ie-Ming
Mutations in BRAF and KRAS characterize the development of low-grade ovarian serous carcinoma.
Journal of the National Cancer Institute 2003;95(6):484-6.
2003: Tong Betty C; Ha Patrick K; Dhir Karan; Xing Mingzhao; Westra William H; Sidransky David; Califano Joseph A
Mitochondrial DNA alterations in thyroid cancer.
Journal of surgical oncology 2003;82(3):170-3.
2003: Harden Susan V; Guo Zhongmin; Epstein Jonathan I; Sidransky David
Quantitative GSTP1 methylation clearly distinguishes benign prostatic tissue and limited prostate adenocarcinoma.
The Journal of urology 2003;169(3):1138-42.
2003: Mambo Elizabeth; Gao Xiangqun; Cohen Yoram; Guo Zhongmin; Talalay Paul; Sidransky David
Electrophile and oxidant damage of mitochondrial DNA leading to rapid evolution of homoplasmic mutations.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(4):1838-43.
2003: Jerónimo C; Henrique R; Campos P F; Oliveira J; Caballero O L; Lopes C; Sidransky D
Endothelin B receptor gene hypermethylation in prostate adenocarcinoma.
Journal of clinical pathology 2003;56(1):52-5.
2002: Yamashita Keishi; Upadhyay Sunil; Osada Motonobu; Hoque Mohammad O; Xiao Yan; Mori Masaki; Sato Fumiaki; Meltzer Stephen J; Sidransky David
Pharmacologic unmasking of epigenetically silenced tumor suppressor genes in esophageal squamous cell carcinoma.
Cancer cell 2002;2(6):485-95.
2002: Jerónimo Carmen; Usadel Henning; Henrique Rui; Silva Cristina; Oliveira Jorge; Lopes Carlos; Sidransky David
Quantitative GSTP1 hypermethylation in bodily fluids of patients with prostate cancer.
Urology 2002;60(6):1131-5.
2002: Ha Patrick K; Pilkington Thomas A; Westra William H; Sciubba James; Sidransky David; Califano Joseph A
Progression of microsatellite instability from premalignant lesions to tumors of the head and neck.
International journal of cancer. Journal international du cancer 2002;102(6):615-7.
2002: Zangen Rachel; Harden Susan; Cohen Daniel; Parrella Paola; Sidransky David
Mouse mammary tumor-like env gene as a molecular marker for breast cancer?
International journal of cancer. Journal international du cancer 2002;102(3):304-7.
2002: Hu Ying Chuan; Sidransky David; Ahrendt Steven A
Molecular detection approaches for smoking associated tumors.
Oncogene 2002;21(48):7289-97.
2002: Dong Seung Myung; Sidransky David
Absence of ST7 gene alterations in human cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2939-41.
2002: Ha Patrick K; Tong Betty C; Westra William H; Sanchez-Cespedes Montserrat; Parrella Paola; Zahurak Marianna; Sidransky David; Califano Joseph A
Mitochondrial C-tract alteration in premalignant lesions of the head and neck: a marker for progression and clonal proliferation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(7):2260-5.
2002: Sanchez-Cespedes Montserrat; Parrella Paola; Esteller Manel; Nomoto Shuji; Trink Barry; Engles James M; Westra William H; Herman James G; Sidransky David
Inactivation of LKB1/STK11 is a common event in adenocarcinomas of the lung.
Cancer research 2002;62(13):3659-62.
2002: Gonzalgo Mark L; Eisenberger Claus F; Lee Shing M; Trock Bruce J; Marshall Fray F; Hortopan Steven; Sidransky David; Schoenberg Mark P
Prognostic significance of preoperative molecular serum analysis in renal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(6):1878-81.
2002: Patturajan Meera; Nomoto Shuji; Sommer Matthias; Fomenkov Alexey; Hibi Kenji; Zangen Rachel; Poliak Nina; Califano Joseph; Trink Barry; Ratovitski Edward; Sidransky David
DeltaNp63 induces beta-catenin nuclear accumulation and signaling.
Cancer cell 2002;1(4):369-79.
2002: Caballero Otávia L; Resto Vicente; Patturajan Meera; Meerzaman Daoud; Guo Ming Zhou; Engles James; Yochem Robert; Ratovitski Edward; Sidransky David; Jen Jin
Interaction and colocalization of PGP9.5 with JAB1 and p27(Kip1).
Oncogene 2002;21(19):3003-10.
2002: Jerónimo Carmen; Varzim Graça; Henrique Rui; Oliveira Jorge; Bento Maria José; Silva Cristina; Lopes Carlos; Sidransky David
I105V polymorphism and promoter methylation of the GSTP1 gene in prostate adenocarcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(5):445-50.
2002: Ha Patrick K; Pai Sara I; Westra William H; Gillison Maura L; Tong Betty C; Sidransky David; Califano Joseph A
Real-time quantitative PCR demonstrates low prevalence of human papillomavirus type 16 in premalignant and malignant lesions of the oral cavity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(5):1203-9.
2002: Sidransky David
Emerging molecular markers of cancer.
Nature reviews. Cancer 2002;2(3):210-9.
2002: Cheng Hong-Lin; Trink Barry; Tzai Tzong-Shin; Liu Hsiao-Sheng; Chan Shih-Huang; Ho Chung-Liang; Sidransky David; Chow Nan-Haw
Overexpression of c-met as a prognostic indicator for transitional cell carcinoma of the urinary bladder: a comparison with p53 nuclear accumulation.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(6):1544-50.
2002: Ahrendt Steven A; Yang Stephen C; Wu Li; Roig Carmen M; Russell Pamela; Westra William H; Jen Jin; Brock Malcolm V; Heitmiller Richard F; Sidransky David
Molecular assessment of lymph nodes in patients with resected stage I non-small cell lung cancer: preliminary results of a prospective study.
The Journal of thoracic and cardiovascular surgery 2002;123(3):466-73; discussion 473-4.
2002: Nomoto Shuji; Yamashita Katsuya; Koshikawa Katsumi; Nakao Akimasa; Sidransky David
Mitochondrial D-loop mutations as clonal markers in multicentric hepatocellular carcinoma and plasma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(2):481-7.
2002: Sun Xiyuan; Hung K; Wu L; Sidransky D; Guo Baochuan
Detection of tumor mutations in the presence of excess amounts of normal DNA.
Nature biotechnology 2002;20(2):186-9.
2002: Dong Seung Myung; Pai Sara I; Rha Seo-Hee; Hildesheim Allan; Kurman Robert J; Schwartz Peter E; Mortel Rodrigue; McGowan Larry; Greenberg Mitchell D; Barnes Willard A; Sidransky David
Detection and quantitation of human papillomavirus DNA in the plasma of patients with cervical carcinoma.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2002;11(1):3-6.
2002: Usadel Henning; Brabender Jan; Danenberg Kathy D; Jerónimo Carmen; Harden Susan; Engles James; Danenberg Peter V; Yang Stephen; Sidransky David
Quantitative adenomatous polyposis coli promoter methylation analysis in tumor tissue, serum, and plasma DNA of patients with lung cancer.
Cancer research 2002;62(2):371-5.
2002: Nomoto Shuji; Sanchez-Cespedes Montserrant; Sidransky David
Identification of mtDNA mutations in human cancer.
Methods in molecular biology (Clifton, N.J.) 2002;197():107-17.
2001: Forastiere A; Koch W; Trotti A; Sidransky D
Head and neck cancer.
The New England journal of medicine 2001;345(26):1890-900.
2001: Nacht M; Dracheva T; Gao Y; Fujii T; Chen Y; Player A; Akmaev V; Cook B; Dufault M; Zhang M; Zhang W; Guo M; Curran J; Han S; Sidransky D; Buetow K; Madden S L; Jen J
Molecular characteristics of non-small cell lung cancer.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15203-8.
2001: Wolf P; Hu Y C; Doffek K; Sidransky D; Ahrendt S A
O(6)-Methylguanine-DNA methyltransferase promoter hypermethylation shifts the p53 mutational spectrum in non-small cell lung cancer.
Cancer research 2001;61(22):8113-7.
2001: Jerónimo C; Usadel H; Henrique R; Oliveira J; Lopes C; Nelson W G; Sidransky D
Quantitation of GSTP1 methylation in non-neoplastic prostatic tissue and organ-confined prostate adenocarcinoma.
Journal of the National Cancer Institute 2001;93(22):1747-52.
2001: Parrella P; Xiao Y; Fliss M; Sanchez-Cespedes M; Mazzarelli P; Rinaldi M; Nicol T; Gabrielson E; Cuomo C; Cohen D; Pandit S; Spencer M; Rabitti C; Fazio V M; Sidransky D
Detection of mitochondrial DNA mutations in primary breast cancer and fine-needle aspirates.
Cancer research 2001;61(20):7623-6.
2001: Sanchez-Cespedes M; Parrella P; Nomoto S; Cohen D; Xiao Y; Esteller M; Jeronimo C; Jordan R C; Nicol T; Koch W M; Schoenberg M; Mazzarelli P; Fazio V M; Sidransky D
Identification of a mononucleotide repeat as a major target for mitochondrial DNA alterations in human tumors.
Cancer research 2001;61(19):7015-9.
2001: Caballero O L; Cohen D; Liu Q; Esteller M; Bonacum J; White P; Engles J; Yochem R; Herman J G; Westra W H; Lengauer C; Sidransky D; Jen J
Loss of chromosome arms 3p and 9p and inactivation of P16 (INK4a) in normal epithelium of patients with primary lung cancer.
Genes, chromosomes & cancer 2001;32(2):119-25.
2001: Ahrendt S A; Decker P A; Alawi E A; Zhu Yr Y R; Sanchez-Cespedes M; Yang S C; Haasler G B; Kajdacsy-Balla A; Demeure M J; Sidransky D
Cigarette smoking is strongly associated with mutation of the K-ras gene in patients with primary adenocarcinoma of the lung.
Cancer 2001;92(6):1525-30.
2001: Cairns P; Esteller M; Herman J G; Schoenberg M; Jeronimo C; Sanchez-Cespedes M; Chow N H; Grasso M; Wu L; Westra W B; Sidransky D
Molecular detection of prostate cancer in urine by GSTP1 hypermethylation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(9):2727-30.
2001: Bittencourt Rosas S L; Caballero O L; Dong S M; da Costa Carvalho M da G; Sidransky D; Jen J
Methylation status in the promoter region of the human PGP9.5 gene in cancer and normal tissues.
Cancer letters 2001;170(1):73-9.
2001: Jerónimo C; Nomoto S; Caballero O L; Usadel H; Henrique R; Varzim G; Oliveira J; Lopes C; Fliss M S; Sidransky D
Mitochondrial mutations in early stage prostate cancer and bodily fluids.
Oncogene 2001;20(37):5195-8.
2001: Rha S H; Dong S M; Jen J; Nicol T; Sidransky D
Molecular detection of cervical intraepithelial neoplasia and cervical carcinoma by microsatellite analysis of Papanicolaou smears.
International journal of cancer. Journal international du cancer 2001;93(3):424-9.
2001: Dong S M; Kim H S; Rha S H; Sidransky D
Promoter hypermethylation of multiple genes in carcinoma of the uterine cervix.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):1982-6.
2001: Guo Z; Yamaguchi K; Sanchez-Cespedes M; Westra W H; Koch W M; Sidransky D
Allelic losses in OraTest-directed biopsies of patients with prior upper aerodigestive tract malignancy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):1963-8.
2001: Parrella P; Caballero O L; Sidransky D; Merbs S L
Detection of c-myc amplification in uveal melanoma by fluorescent in situ hybridization.
Investigative ophthalmology & visual science 2001;42(8):1679-84.
2001: Brabender J; Usadel H; Danenberg K D; Metzger R; Schneider P M; Lord R V; Wickramasinghe K; Lum C E; Park J; Salonga D; Singer J; Sidransky D; Hölscher A H; Meltzer S J; Danenberg P V
Adenomatous polyposis coli gene promoter hypermethylation in non-small cell lung cancer is associated with survival.
Oncogene 2001;20(27):3528-32.
2001: Minamoto T; Buschmann T; Habelhah H; Matusevich E; Tahara H; Boerresen-Dale A L; Harris C; Sidransky D; Ronai Z
Distinct pattern of p53 phosphorylation in human tumors.
Oncogene 2001;20(26):3341-7.
2001: Fisher M J; Virmani A K; Wu L; Aplenc R; Harper J C; Powell S M; Rebbeck T R; Sidransky D; Gazdar A F; El-Deiry W S
Nucleotide substitution in the ectodomain of trail receptor DR4 is associated with lung cancer and head and neck cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(6):1688-97.
2001: Dong S M; Traverso G; Johnson C; Geng L; Favis R; Boynton K; Hibi K; Goodman S N; D'Allessio M; Paty P; Hamilton S R; Sidransky D; Barany F; Levin B; Shuber A; Kinzler K W; Vogelstein B; Jen J
Detecting colorectal cancer in stool with the use of multiple genetic targets.
Journal of the National Cancer Institute 2001;93(11):858-65.
2001: Spafford M F; Koch W M; Reed A L; Califano J A; Xu L H; Eisenberger C F; Yip L; Leong P L; Wu L; Liu S X; Jerónimo C; Westra W H; Sidransky D
Detection of head and neck squamous cell carcinoma among exfoliated oral mucosal cells by microsatellite analysis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(3):607-12.
2001: Sanchez-Cespedes M; Decker P A; Doffek K M; Esteller M; Westra W H; Alawi E A; Herman J G; Demeure M J; Sidransky D; Ahrendt S A
Increased loss of chromosome 9p21 but not p16 inactivation in primary non-small cell lung cancer from smokers.
Cancer research 2001;61(5):2092-6.
2001: Rocco J W; Sidransky D
p16(MTS-1/CDKN2/INK4a) in cancer progression.
Experimental cell research 2001;264(1):42-55.
2001: Sanchez-Cespedes M; Ahrendt S A; Piantadosi S; Rosell R; Monzo M; Wu L; Westra W H; Yang S C; Jen J; Sidransky D
Chromosomal alterations in lung adenocarcinoma from smokers and nonsmokers.
Cancer research 2001;61(4):1309-13.
2001: Rosas S L; Koch W; da Costa Carvalho M G; Wu L; Califano J; Westra W; Jen J; Sidransky D
Promoter hypermethylation patterns of p16, O6-methylguanine-DNA-methyltransferase, and death-associated protein kinase in tumors and saliva of head and neck cancer patients.
Cancer research 2001;61(3):939-42.
2001: Ratovitski E A; Patturajan M; Hibi K; Trink B; Yamaguchi K; Sidransky D
p53 associates with and targets Delta Np63 into a protein degradation pathway.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(4):1817-22.
2001: Xu L; Chow J; Bonacum J; Eisenberger C; Ahrendt S A; Spafford M; Wu L; Lee S M; Piantadosi S; Tockman M S; Sidransky D; Jen J
Microsatellite instability at AAAG repeat sequences in respiratory tract cancers.
International journal of cancer. Journal international du cancer 2001;91(2):200-4.
2000: Capone R B; Pai S I; Koch W M; Gillison M L; Danish H N; Westra W H; Daniel R; Shah K V; Sidransky D
Detection and quantitation of human papillomavirus (HPV) DNA in the sera of patients with HPV-associated head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4171-5.
2000: Yamaguchi K; Patturajan M; Trink B; Usadel H; Koch W; Jen J; Sidransky D
Circulating antibodies to p40(AIS) in the sera of respiratory tract cancer patients.
International journal of cancer. Journal international du cancer 2000;89(6):524-8.
2000: Chow N H; Cairns P; Eisenberger C F; Schoenberg M P; Taylor D C; Epstein J I; Sidransky D
Papillary urothelial hyperplasia is a clonal precursor to papillary transitional cell bladder cancer.
International journal of cancer. Journal international du cancer 2000;89(6):514-8.
2000: Kawakami K; Brabender J; Lord R V; Groshen S; Greenwald B D; Krasna M J; Yin J; Fleisher A S; Abraham J M; Beer D G; Sidransky D; Huss H T; Demeester T R; Eads C; Laird P W; Ilson D H; Kelsen D P; Harpole D; Moore M B; Danenberg K D; Danenberg P V; Meltzer S J
Hypermethylated APC DNA in plasma and prognosis of patients with esophageal adenocarcinoma.
Journal of the National Cancer Institute 2000;92(22):1805-11.
2000: Resto V A; Caballero O L; Buta M R; Westra W H; Wu L; Westendorf J M; Jen J; Hieter P; Sidransky D
A putative oncogenic role for MPP11 in head and neck squamous cell cancer.
Cancer research 2000;60(19):5529-35.
2000: Shah S I; Yip L; Greenberg B; Califano J A; Chow J; Eisenberger C F; Lee D J; Sewell D A; Reed A L; Lango M; Jen J; Koch W M; Sidransky D
Two distinct regions of loss on chromosome arm 4q in primary head and neck squamous cell carcinoma.
Archives of otolaryngology--head & neck surgery 2000;126(9):1073-6.
2000: Esteller M; Sparks A; Toyota M; Sanchez-Cespedes M; Capella G; Peinado M A; Gonzalez S; Tarafa G; Sidransky D; Meltzer S J; Baylin S B; Herman J G
Analysis of adenomatous polyposis coli promoter hypermethylation in human cancer.
Cancer research 2000;60(16):4366-71.
2000: Medintz I L; Lee C C; Wong W W; Pirkola K; Sidransky D; Mathies R A
Loss of heterozygosity assay for molecular detection of cancer using energy-transfer primers and capillary array electrophoresis.
Genome research 2000;10(8):1211-8.
2000: Ahrendt S A; Chow J T; Yang S C; Wu L; Zhang M J; Jen J; Sidransky D
Alcohol consumption and cigarette smoking increase the frequency of p53 mutations in non-small cell lung cancer.
Cancer research 2000;60(12):3155-9.
2000: Yamaguchi K; Wu L; Caballero O L; Hibi K; Trink B; Resto V; Cairns P; Okami K; Koch W M; Sidransky D; Jen J
Frequent gain of the p40/p51/p63 gene locus in primary head and neck squamous cell carcinoma.
International journal of cancer. Journal international du cancer 2000;86(5):684-9.
2000: Ahrendt S A; Decker P A; Doffek K; Wang B; Xu L; Demeure M J; Jen J; Sidransky D
Microsatellite instability at selected tetranucleotide repeats is associated with p53 mutations in non-small cell lung cancer.
Cancer research 2000;60(9):2488-91.
2000: Esteller M; Toyota M; Sanchez-Cespedes M; Capella G; Peinado M A; Watkins D N; Issa J P; Sidransky D; Baylin S B; Herman J G
Inactivation of the DNA repair gene O6-methylguanine-DNA methyltransferase by promoter hypermethylation is associated with G to A mutations in K-ras in colorectal tumorigenesis.
Cancer research 2000;60(9):2368-71.
2000: Hibi K; Trink B; Patturajan M; Westra W H; Caballero O L; Hill D E; Ratovitski E A; Jen J; Sidransky D
AIS is an oncogene amplified in squamous cell carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5462-7.
2000: Gillison M L; Koch W M; Capone R B; Spafford M; Westra W H; Wu L; Zahurak M L; Daniel R W; Viglione M; Symer D E; Shah K V; Sidransky D
Evidence for a causal association between human papillomavirus and a subset of head and neck cancers.
Journal of the National Cancer Institute 2000;92(9):709-20.
2000: Jen J; Wu L; Sidransky D
An overview on the isolation and analysis of circulating tumor DNA in plasma and serum.
Annals of the New York Academy of Sciences 2000;906():8-12.
2000: Sidransky D
Circulating DNA. What we know and what we need to learn.
Annals of the New York Academy of Sciences 2000;906():1-4.
2000: Halachmi S; DeMarzo A M; Chow N H; Halachmi N; Smith A E; Linn J F; Nativ O; Epstein J I; Schoenberg M P; Sidransky D
Genetic alterations in urinary bladder carcinosarcoma: evidence of a common clonal origin.
European urology 2000;37(3):350-7.
2000: Fliss M S; Usadel H; Caballero O L; Wu L; Buta M R; Eleff S M; Jen J; Sidransky D
Facile detection of mitochondrial DNA mutations in tumors and bodily fluids.
Science (New York, N.Y.) 2000;287(5460):2017-9.
2000: Sanchez-Cespedes M; Okami K; Cairns P; Sidransky D
Molecular analysis of the candidate tumor suppressor gene ING1 in human head and neck tumors with 13q deletions.
Genes, chromosomes & cancer 2000;27(3):319-22.
2000: Sanchez-Cespedes M; Esteller M; Wu L; Nawroz-Danish H; Yoo G H; Koch W M; Jen J; Herman J G; Sidransky D
Gene promoter hypermethylation in tumors and serum of head and neck cancer patients.
Cancer research 2000;60(4):892-5.
2000: Califano J; Westra W H; Meininger G; Corio R; Koch W M; Sidransky D
Genetic progression and clonal relationship of recurrent premalignant head and neck lesions.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(2):347-52.
2000: Lynch H T; McComb R D; Osborn N K; Wolpert P A; Lynch J F; Wszolek Z K; Sidransky D; Steg R E
Predominance of brain tumors in an extended Li-Fraumeni (SBLA) kindred, including a case of Sturge-Weber syndrome.
Cancer 2000;88(2):433-9.
2000: Califano J; Koch W; Sidransky D; Westra W H
Inverted sinonasal papilloma : a molecular genetic appraisal of its putative status as a Precursor to squamous cell carcinoma.
The American journal of pathology 2000;156(1):333-7.
2000: Ahrendt S A; Rashid A; Chow J T; Eisenberger C F; Pitt H A; Sidransky D
p53 overexpression and K-ras gene mutations in primary sclerosing cholangitis-associated biliary tract cancer.
Journal of hepato-biliary-pancreatic surgery 2000;7(4):426-31.
1999: Eisenberger C F; Schoenberg M; Enger C; Hortopan S; Shah S; Chow N H; Marshall F F; Sidransky D
Diagnosis of renal cancer by molecular urinalysis.
Journal of the National Cancer Institute 1999;91(23):2028-32.
1999: Sanchez-Cespedes M; Reed A L; Buta M; Wu L; Westra W H; Herman J G; Yang S C; Jen J; Sidransky D
Inactivation of the INK4A/ARF locus frequently coexists with TP53 mutations in non-small cell lung cancer.
Oncogene 1999;18(43):5843-9.
1999: Taylor D; Koch W M; Zahurak M; Shah K; Sidransky D; Westra W H
Immunohistochemical detection of p53 protein accumulation in head and neck cancer: correlation with p53 gene alterations.
Human pathology 1999;30(10):1221-5.
1999: Koch W M; Lango M; Sewell D; Zahurak M; Sidransky D
Head and neck cancer in nonsmokers: a distinct clinical and molecular entity.
The Laryngoscope 1999;109(10):1544-51.
1999: Ahrendt S A; Sidransky D
The potential of molecular screening.
Surgical oncology clinics of North America 1999;8(4):641-56, vi.
1999: Docimo S G; Chow N H; Steiner G; Silver R I; Rodriguez R; Kinsman S; Sidransky D; Schoenberg M
Detection of adenocarcinoma by urinary microsatellite analysis after augmentation cystoplasty.
Urology 1999;54(3):561.
1999: Sanchez-Cespedes M; Esteller M; Hibi K; Cope F O; Westra W H; Piantadosi S; Herman J G; Jen J; Sidransky D
Molecular detection of neoplastic cells in lymph nodes of metastatic colorectal cancer patients predicts recurrence.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(9):2450-4.
1999: Eisenberger C F; Wu L; Nicol T; Shah S I; Sidransky D; Westra W H
Comparative microsatellite analysis in discerning origin of disseminated tumor: the case of a patient with malignant ascites and a history of multiple tumors.
Human pathology 1999;30(9):1111-3.
1999: Hibi K; Westra W H; Borges M; Goodman S; Sidransky D; Jen J
PGP9.5 as a candidate tumor marker for non-small-cell lung cancer.
The American journal of pathology 1999;155(3):711-5.
1999: Califano J; Leong P L; Koch W M; Eisenberger C F; Sidransky D; Westra W H
Second esophageal tumors in patients with head and neck squamous cell carcinoma: an assessment of clonal relationships.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(7):1862-7.
1999: Parrella P; Sidransky D; Merbs S L
Allelotype of posterior uveal melanoma: implications for a bifurcated tumor progression pathway.
Cancer research 1999;59(13):3032-7.
1999: Ahrendt S A; Halachmi S; Chow J T; Wu L; Halachmi N; Yang S C; Wehage S; Jen J; Sidransky D
Rapid p53 sequence analysis in primary lung cancer using an oligonucleotide probe array.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(13):7382-7.
1999: Okami K; Reed A L; Cairns P; Koch W M; Westra W H; Wehage S; Jen J; Sidransky D
Cyclin D1 amplification is independent of p16 inactivation in head and neck squamous cell carcinoma.
Oncogene 1999;18(23):3541-5.
1999: Ahrendt S A; Eisenberger C F; Yip L; Rashid A; Chow J T; Pitt H A; Sidransky D
Chromosome 9p21 loss and p16 inactivation in primary sclerosing cholangitis-associated cholangiocarcinoma.
The Journal of surgical research 1999;84(1):88-93.
1999: Yamaguchi K; Okami K; Hibi K; Wehage S L; Jen J; Sidransky D
Mutation analysis of hBUB1 in aneuploid HNSCC and lung cancer cell lines.
Cancer letters 1999;139(2):183-7.
1999: Califano J; Westra W H; Koch W; Meininger G; Reed A; Yip L; Boyle J O; Lonardo F; Sidransky D
Unknown primary head and neck squamous cell carcinoma: molecular identification of the site of origin.
Journal of the National Cancer Institute 1999;91(7):599-604.
1999: Cairns P; Sidransky D
Molecular methods for the diagnosis of cancer.
Biochimica et biophysica acta 1999;1423(2):C11-8.
1999: Anbazhagan R; Merlo A; Sidransky D; Gabrielson E
Absence of intragenic mismatch mutations in small cell lung cancers with microsatellite instability.
International journal of cancer. Journal international du cancer 1999;80(6):944-5.
1999: Merbs S L; Sidransky D
Analysis of p16 (CDKN2/MTS-1/INK4A) alterations in primary sporadic uveal melanoma.
Investigative ophthalmology & visual science 1999;40(3):779-83.
1999: Ahrendt S A; Chow J T; Xu L H; Yang S C; Eisenberger C F; Esteller M; Herman J G; Wu L; Decker P A; Jen J; Sidransky D
Molecular detection of tumor cells in bronchoalveolar lavage fluid from patients with early stage lung cancer.
Journal of the National Cancer Institute 1999;91(4):332-9.
1999: Esteller M; Sanchez-Cespedes M; Rosell R; Sidransky D; Baylin S B; Herman J G
Detection of aberrant promoter hypermethylation of tumor suppressor genes in serum DNA from non-small cell lung cancer patients.
Cancer research 1999;59(1):67-70.
1998: Hibi K; Liu Q; Beaudry G A; Madden S L; Westra W H; Wehage S L; Yang S C; Heitmiller R F; Bertelsen A H; Sidransky D; Jen J
Serial analysis of gene expression in non-small cell lung cancer.
Cancer research 1998;58(24):5690-4.
1998: Sanchez-Cespedes M; Cairns P; Jen J; Sidransky D
Degenerate oligonucleotide-primed PCR (DOP-PCR): evaluation of its reliability for screening of genetic alterations in neoplasia.
BioTechniques 1998;25(6):1036-8.
1998: Baker L A; Chow N H; Docimo S G; Gearhart J P; Sidransky D; Schoenberg M P
Microsatellite deoxyribonucleic acid analysis to detect bladder cancer in bladder exstrophy.
The Journal of urology 1998;160(6 Pt 1):2192-3.
1998: Boland C R; Thibodeau S N; Hamilton S R; Sidransky D; Eshleman J R; Burt R W; Meltzer S J; Rodriguez-Bigas M A; Fodde R; Ranzani G N; Srivastava S
A National Cancer Institute Workshop on Microsatellite Instability for cancer detection and familial predisposition: development of international criteria for the determination of microsatellite instability in colorectal cancer.
Cancer research 1998;58(22):5248-57.
1998: Halachmi N; Halachmi S; Evron E; Cairns P; Okami K; Saji M; Westra W H; Zeiger M A; Jen J; Sidransky D
Somatic mutations of the PTEN tumor suppressor gene in sporadic follicular thyroid tumors.
Genes, chromosomes & cancer 1998;23(3):239-43.
1998: Westra W H; Sidransky D
Phenotypic and genotypic disparity in premalignant lesions: of calm water and crocodiles.
Journal of the National Cancer Institute 1998;90(20):1500-1.
1998: Pai S I; Wu G S; Ozören N; Wu L; Jen J; Sidransky D; El-Deiry W S
Rare loss-of-function mutation of a death receptor gene in head and neck cancer.
Cancer research 1998;58(16):3513-8.
1998: Rocco J W; Li D; Liggett W H; Duan L; Saunders J K; Sidransky D; O'Malley B W
p16INK4A adenovirus-mediated gene therapy for human head and neck squamous cell cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(7):1697-704.
1998: Nawroz-Danish H M; Koch W M; Westra W H; Yoo G; Sidransky D
Lack of BRCA2 alterations in primary head and neck squamous cell carcinoma.
Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery 1998;119(1):21-5.
1998: Leong P P; Rezai B; Koch W M; Reed A; Eisele D; Lee D J; Sidransky D; Jen J; Westra W H
Distinguishing second primary tumors from lung metastases in patients with head and neck squamous cell carcinoma.
Journal of the National Cancer Institute 1998;90(13):972-7.
1998: Trink B; Okami K; Wu L; Sriuranpong V; Jen J; Sidransky D
A new human p53 homologue.
Nature medicine 1998;4(7):747-8.
1998: Cairns P; Evron E; Okami K; Halachmi N; Esteller M; Herman J G; Bose S; Wang S I; Parsons R; Sidransky D
Point mutation and homozygous deletion of PTEN/MMAC1 in primary bladder cancers.
Oncogene 1998;16(24):3215-8.
1998: Trink B; Pai S I; Spunt S L; Raman V; Cairns P; Jen J; Gabrielson E; Sukumar S; Sidransky D
Absence of TSG101 transcript abnormalities in human cancers.
Oncogene 1998;16(21):2815-8.
1998: Hibi K; Robinson C R; Booker S; Wu L; Hamilton S R; Sidransky D; Jen J
Molecular detection of genetic alterations in the serum of colorectal cancer patients.
Cancer research 1998;58(7):1405-7.
1998: Liggett W H; Sidransky D
Role of the p16 tumor suppressor gene in cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(3):1197-206.
1998: Cairns J P; Chiang P W; Ramamoorthy S; Kurnit D M; Sidransky D
A comparison between microsatellite and quantitative PCR analyses to detect frequent p16 copy number changes in primary bladder tumors.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):441-4.
1998: Okami K; Wu L; Riggins G; Cairns P; Goggins M; Evron E; Halachmi N; Ahrendt S A; Reed A L; Hilgers W; Kern S E; Koch W M; Sidransky D; Jen J
Analysis of PTEN/MMAC1 alterations in aerodigestive tract tumors.
Cancer research 1998;58(3):509-11.
1998: Suzuki H; Freije D; Nusskern D R; Okami K; Cairns P; Sidransky D; Isaacs W B; Bova G S
Interfocal heterogeneity of PTEN/MMAC1 gene alterations in multiple metastatic prostate cancer tissues.
Cancer research 1998;58(2):204-9.
1997: Linn J F; Lango M; Halachmi S; Schoenberg M P; Sidransky D
Microsatellite analysis and telomerase activity in archived tissue and urine samples of bladder cancer patients.
International journal of cancer. Journal international du cancer 1997;74(6):625-9.
1997: Okami K; Cairns P; Westra W H; Linn J F; Ahrendt S A; Wu L; Sidransky D; Jen J
Detailed deletion mapping at chromosome 9p21 in non-small cell lung cancer by microsatellite analysis and fluorescence in situ hybridization.
International journal of cancer. Journal international du cancer 1997;74(6):588-92.
1997: Cairns P; Okami K; King P; Bonacum J; Ahrendt S; Wu L; Mao L; Jen J; Sidransky D
Genomic organization and mutation analysis of Hel-N1 in lung cancers with chromosome 9p21 deletions.
Cancer research 1997;57(23):5356-9.
1997: Cairns P; Okami K; Halachmi S; Halachmi N; Esteller M; Herman J G; Jen J; Isaacs W B; Bova G S; Sidransky D
Frequent inactivation of PTEN/MMAC1 in primary prostate cancer.
Cancer research 1997;57(22):4997-5000.
1997: Sidransky D
Nucleic acid-based methods for the detection of cancer.
Science (New York, N.Y.) 1997;278(5340):1054-9.
1997: Arap W; Knudsen E; Sewell D A; Sidransky D; Wang J Y; Huang H J; Cavenee W K
Functional analysis of wild-type and malignant glioma derived CDKN2Abeta alleles: evidence for an RB-independent growth suppressive pathway.
Oncogene 1997;15(17):2013-20.
1997: Wang S I; Puc J; Li J; Bruce J N; Cairns P; Sidransky D; Parsons R
Somatic mutations of PTEN in glioblastoma multiforme.
Cancer research 1997;57(19):4183-6.
1997: Wang Y; Hung S C; Linn J F; Steiner G; Glazer A N; Sidransky D; Mathies R A
Microsatellite-based cancer detection using capillary array electrophoresis and energy-transfer fluorescent primers.
Electrophoresis 1997;18(10):1742-9.
1997: Ahrendt S A; Yang S C; Wu L; Westra W H; Jen J; Califano J A; Sidransky D
Comparison of oncogene mutation detection and telomerase activity for the molecular staging of non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(7):1207-14.
1997: Evron E; Cairns P; Halachmi N; Ahrendt S A; Reed A L; Sidransky D
Normal polymorphism in the incomplete trinucleotide repeat of the arginine-rich protein gene.
Cancer research 1997;57(14):2888-9.
1997: Steiner G; Schoenberg M P; Linn J F; Mao L; Sidransky D
Detection of bladder cancer recurrence by microsatellite analysis of urine.
Nature medicine 1997;3(6):621-4.
1997: Jarrard D F; Bova G S; Ewing C M; Pin S S; Nguyen S H; Baylin S B; Cairns P; Sidransky D; Herman J G; Isaacs W B
Deletional, mutational, and methylation analyses of CDKN2 (p16/MTS1) in primary and metastatic prostate cancer.
Genes, chromosomes & cancer 1997;19(2):90-6.
1997: Lee D J; Koch W M; Yoo G; Lango M; Reed A; Califano J; Brennan J A; Westra W H; Zahurak M; Sidransky D
Impact of chromosome 14q loss on survival in primary head and neck squamous cell carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(4):501-5.
1997: Wiest J S; Franklin W A; Otstot J T; Forbey K; Varella-Garcia M; Rao K; Drabkin H; Gemmill R; Ahrent S; Sidransky D; Saccomanno G; Fountain J W; Anderson M W
Identification of a novel region of homozygous deletion on chromosome 9p in squamous cell carcinoma of the lung: the location of a putative tumor suppressor gene.
Cancer research 1997;57(1):1-6.
1997: Wiest J S; Franklin W A; Drabkin H; Gemmill R; Sidransky D; Anderson M W
Genetic markers for early detection of lung cancer and outcome measures for response to chemoprevention.
Journal of cellular biochemistry. Supplement 1997;28-29():64-73.
1996: Califano J A; Johns M M; Westra W H; Lango M N; Eisele D; Saji M; Zeiger M A; Udelsman R; Koch W M; Sidransky D
An allelotype of papillary thyroid cancer.
International journal of cancer. Journal international du cancer 1996;69(6):442-4.
1996: Califano J; Ahrendt S A; Meininger G; Westra W H; Koch W M; Sidransky D
Detection of telomerase activity in oral rinses from head and neck squamous cell carcinoma patients.
Cancer research 1996;56(24):5720-2.
1996: Steiner G; Sidransky D
Molecular differential diagnosis of renal carcinoma: from microscopes to microsatellites.
The American journal of pathology 1996;149(6):1791-5.
1996: Moskaluk C A; Heitmiller R; Zahurak M; Schwab D; Sidransky D; Hamilton S R
p53 and p21(WAF1/CIP1/SDI1) gene products in Barrett esophagus and adenocarcinoma of the esophagus and esophagogastric junction.
Human pathology 1996;27(11):1211-20.
1996: Koch W M; Brennan J A; Zahurak M; Goodman S N; Westra W H; Schwab D; Yoo G H; Lee D J; Forastiere A A; Sidransky D
p53 mutation and locoregional treatment failure in head and neck squamous cell carcinoma.
Journal of the National Cancer Institute 1996;88(21):1580-6.
1996: Steiner G; Cairns P; Polascik T J; Marshall F F; Epstein J I; Sidransky D; Schoenberg M
High-density mapping of chromosomal arm 1q in renal collecting duct carcinoma: region of minimal deletion at 1q32.1-32.2.
Cancer research 1996;56(21):5044-6.
1996: Yao S L; Akhtar A J; McKenna K A; Bedi G C; Sidransky D; Mabry M; Ravi R; Collector M I; Jones R J; Sharkis S J; Fuchs E J; Bedi A
Selective radiosensitization of p53-deficient cells by caffeine-mediated activation of p34cdc2 kinase.
Nature medicine 1996;2(10):1140-3.
1996: Liggett W H; Sewell D A; Rocco J; Ahrendt S A; Koch W; Sidransky D
p16 and p16 beta are potent growth suppressors of head and neck squamous carcinoma cells in vitro.
Cancer research 1996;56(18):4119-23.
1996: Sidransky D
Is human patched the gatekeeper of common skin cancers?
Nature genetics 1996;14(1):7-8.
1996: Nawroz H; Koch W; Anker P; Stroun M; Sidransky D
Microsatellite alterations in serum DNA of head and neck cancer patients.
Nature medicine 1996;2(9):1035-7.
1996: Sidransky D
Advances in cancer detection.
Scientific American 1996;275(3):104-9.
1996: Reed A L; Califano J; Cairns P; Westra W H; Jones R M; Koch W; Ahrendt S; Eby Y; Sewell D; Nawroz H; Bartek J; Sidransky D
High frequency of p16 (CDKN2/MTS-1/INK4A) inactivation in head and neck squamous cell carcinoma.
Cancer research 1996;56(16):3630-3.
1996: Schutte M; Hruban R H; Hedrick L; Cho K R; Nadasdy G M; Weinstein C L; Bova G S; Isaacs W B; Cairns P; Nawroz H; Sidransky D; Casero R A; Meltzer P S; Hahn S A; Kern S E
DPC4 gene in various tumor types.
Cancer research 1996;56(11):2527-30.
1996: Califano J; van der Riet P; Westra W; Nawroz H; Clayman G; Piantadosi S; Corio R; Lee D; Greenberg B; Koch W; Sidransky D
Genetic progression model for head and neck cancer: implications for field cancerization.
Cancer research 1996;56(11):2488-92.
1996: Bedi G C; Westra W H; Gabrielson E; Koch W; Sidransky D
Multiple head and neck tumors: evidence for a common clonal origin.
Cancer research 1996;56(11):2484-7.
1996: Rosin M P; Miller S J; Schwab D; Westra W H; Sidransky D
Molecular analysis of effectiveness of Mohs' surgical technique.
Lancet 1996;347(9016):1692-3.
1996: Sidransky D
Two tracks but one race? Cancer genetics.
Current biology : CB 1996;6(5):523-5.
1996: Polascik T J; Cairns P; Epstein J I; Fuzesi L; Ro J Y; Marshall F F; Sidransky D; Schoenberg M
Distal nephron renal tumors: microsatellite allelotype.
Cancer research 1996;56(8):1892-5.
1996: Fujii H; Marsh C; Cairns P; Sidransky D; Gabrielson E
Genetic divergence in the clonal evolution of breast cancer.
Cancer research 1996;56(7):1493-7.
1996: Brennan J A; Sidransky D
Molecular staging of head and neck squamous carcinoma.
Cancer metastasis reviews 1996;15(1):3-10.
1996: Johns M M; Westra W H; Califano J A; Eisele D; Koch W M; Sidransky D
Allelotype of salivary gland tumors.
Cancer research 1996;56(5):1151-4.
1996: Schoenberg M; Kiemeney L; Walsh P C; Griffin C A; Sidransky D
Germline translocation t(5;20)(p15;q11) and familial transitional cell carcinoma.
The Journal of urology 1996;155(3):1035-6.
1996: Mao L; Schoenberg M P; Scicchitano M; Erozan Y S; Merlo A; Schwab D; Sidransky D
Molecular detection of primary bladder cancer by microsatellite analysis.
Science (New York, N.Y.) 1996;271(5249):659-62.
1996: Gartenhaus R; Johns M M; Wang P; Rai K; Sidransky D
Mutator phenotype in a subset of chronic lymphocytic leukemia.
Blood 1996;87(1):38-41.
1996: Sidransky D; Hollstein M
Clinical implications of the p53 gene.
Annual review of medicine 1996;47():285-301.
1995: Shapiro G I; Park J E; Edwards C D; Mao L; Merlo A; Sidransky D; Ewen M E; Rollins B J
Multiple mechanisms of p16INK4A inactivation in non-small cell lung cancer cell lines.
Cancer research 1995;55(24):6200-9.
1995: Polascik T J; Cairns P; Chang W Y; Schoenberg M P; Sidransky D
Distinct regions of allelic loss on chromosome 4 in human primary bladder carcinoma.
Cancer research 1995;55(22):5396-9.
1995: Rosin M P; Cairns P; Epstein J I; Schoenberg M P; Sidransky D
Partial allelotype of carcinoma in situ of the human bladder.
Cancer research 1995;55(22):5213-6.
1995: Herman J G; Merlo A; Mao L; Lapidus R G; Issa J P; Davidson N E; Sidransky D; Baylin S B
Inactivation of the CDKN2/p16/MTS1 gene is frequently associated with aberrant DNA methylation in all common human cancers.
Cancer research 1995;55(20):4525-30.
1995: Bedi A; Barber J P; Bedi G C; el-Deiry W S; Sidransky D; Vala M S; Akhtar A J; Hilton J; Jones R J
BCR-ABL-mediated inhibition of apoptosis with delay of G2/M transition after DNA damage: a mechanism of resistance to multiple anticancer agents.
Blood 1995;86(3):1148-58.
1995: Chang W Y; Cairns P; Schoenberg M P; Polascik T J; Sidransky D
Novel suppressor loci on chromosome 14q in primary bladder cancer.
Cancer research 1995;55(15):3246-9.
1995: Sidransky D
Importance of chromosome 9p loss in human lung cancer.
Journal of the National Cancer Institute 1995;87(16):1201-2.
1995: Merlo A; Herman J G; Mao L; Lee D J; Gabrielson E; Burger P C; Baylin S B; Sidransky D
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Nature medicine 1995;1(7):686-92.
1995: Sidransky D
Screening for clonal genetic alterations.
European journal of cancer (Oxford, England : 1990) 1995;31A(7-8):1127-9.
1995: Mao L; Merlo A; Bedi G; Shapiro G I; Edwards C D; Rollins B J; Sidransky D
A novel p16INK4A transcript.
Cancer research 1995;55(14):2995-7.
1995: Sidransky D
Molecular genetics of head and neck cancer.
Current opinion in oncology 1995;7(3):229-33.
1995: Rabkin C S; Bedi G; Musaba E; Sunkutu R; Mwansa N; Sidransky D; Biggar R J
AIDS-related Kaposi's sarcoma is a clonal neoplasm.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(3):257-60.
1995: Koch W M; Patel H; Brennan J; Boyle J O; Sidransky D
Squamous cell carcinoma of the head and neck in the elderly.
Archives of otolaryngology--head & neck surgery 1995;121(3):262-5.
1995: Brennan J A; Boyle J O; Koch W M; Goodman S N; Hruban R H; Eby Y J; Couch M J; Forastiere A A; Sidransky D
Association between cigarette smoking and mutation of the p53 gene in squamous-cell carcinoma of the head and neck.
The New England journal of medicine 1995;332(11):712-7.
1995: Sidransky D
Molecular markers in cancer: can we make better predictions?
International journal of cancer. Journal international du cancer 1995;64(1):1-2.
1995: Brennan J A; Mao L; Hruban R H; Boyle J O; Eby Y J; Koch W M; Goodman S N; Sidransky D
Molecular assessment of histopathological staging in squamous-cell carcinoma of the head and neck.
The New England journal of medicine 1995;332(7):429-35.
1995: Cairns P; Tokino K; Eby Y; Sidransky D
Localization of tumor suppressor loci on chromosome 9 in primary human renal cell carcinomas.
Cancer research 1995;55(2):224-7.
1995: Bedi G C; Westra W H; Farzadegan H; Pitha P M; Sidransky D
Microsatellite instability in primary neoplasms from HIV + patients.
Nature medicine 1995;1(1):65-8.
1995: Schoenberg M; Cairns P; Brooks J D; Marshall F F; Epstein J I; Isaacs W B; Sidransky D
Frequent loss of chromosome arms 8p and 13q in collecting duct carcinoma (CDC) of the kidney.
Genes, chromosomes & cancer 1995;12(1):76-80.
1995: Sidransky D
Molecular markers in cancer diagnosis.
Journal of the National Cancer Institute. Monographs 1995;(17):27-9.
1994: Boyle J O; Mao L; Brennan J A; Koch W M; Eisele D W; Saunders J R; Sidransky D
Gene mutations in saliva as molecular markers for head and neck squamous cell carcinomas.
American journal of surgery 1994;168(5):429-32.
1994: Mao L; Lee D J; Tockman M S; Erozan Y S; Askin F; Sidransky D
Microsatellite alterations as clonal markers for the detection of human cancer.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(21):9871-5.
1994: Blaugrund J E; Johns M M; Eby Y J; Ball D W; Baylin S B; Hruban R H; Sidransky D
RET proto-oncogene mutations in inherited and sporadic medullary thyroid cancer.
Human molecular genetics 1994;3(10):1895-7.
1994: Koch W M; Boyle J O; Mao L; Hakim J; Hruban R H; Sidransky D
p53 gene mutations as markers of tumor spread in synchronous oral cancers.
Archives of otolaryngology--head & neck surgery 1994;120(9):943-7.
1994: Yoo G H; Xu H J; Brennan J A; Westra W; Hruban R H; Koch W; Benedict W F; Sidransky D
Infrequent inactivation of the retinoblastoma gene despite frequent loss of chromosome 13q in head and neck squamous cell carcinoma.
Cancer research 1994;54(17):4603-6.
1994: Huang D P; Lo K W; van Hasselt C A; Woo J K; Choi P H; Leung S F; Cheung S T; Cairns P; Sidransky D; Lee J C
A region of homozygous deletion on chromosome 9p21-22 in primary nasopharyngeal carcinoma.
Cancer research 1994;54(15):4003-6.
1994: Cairns P; Mao L; Merlo A; Lee D J; Schwab D; Eby Y; Tokino K; van der Riet P; Blaugrund J E; Sidransky D
Rates of p16 (MTS1) mutations in primary tumors with 9p loss.
Science (New York, N.Y.) 1994;265(5170):415-7.
1994: Thomas S; Brennan J; Martel G; Frazer I; Montesano R; Sidransky D; Hollstein M
Mutations in the conserved regions of p53 are infrequent in betel-associated oral cancers from Papua New Guinea.
Cancer research 1994;54(13):3588-93.
1994: Sidransky D
Molecular screening--how long can we afford to wait?
Journal of the National Cancer Institute 1994;86(13):955-6.
1994: Merlo A; Gabrielson E; Mabry M; Vollmer R; Baylin S B; Sidransky D
Homozygous deletion on chromosome 9p and loss of heterozygosity on 9q, 6p, and 6q in primary human small cell lung cancer.
Cancer research 1994;54(9):2322-6.
1994: Hruban R H; van der Riet P; Erozan Y S; Sidransky D
Brief report: molecular biology and the early detection of carcinoma of the bladder--the case of Hubert H. Humphrey.
The New England journal of medicine 1994;330(18):1276-8.
1994: Merlo A; Mabry M; Gabrielson E; Vollmer R; Baylin S B; Sidransky D
Frequent microsatellite instability in primary small cell lung cancer.
Cancer research 1994;54(8):2098-101.
1994: Mao L; Sidransky D
Cancer screening based on genetic alterations in human tumors.
Cancer research 1994;54(7 Suppl):1939s-1940s.
1994: Mao L; Hruban R H; Boyle J O; Tockman M; Sidransky D
Detection of oncogene mutations in sputum precedes diagnosis of lung cancer.
Cancer research 1994;54(7):1634-7.
1994: Erlich H A; Gorodezky C; Saiki R; Sidransky D; Sninsky J
Molecular biology of cancer, virus and HLA typing.
Revista de investigación clínica; organo del Hospital de Enfermedades de la Nutrición 1994;Suppl():59-61.
1994: Cairns P; Tokino K; Eby Y; Sidransky D
Homozygous deletions of 9p21 in primary human bladder tumors detected by comparative multiplex polymerase chain reaction.
Cancer research 1994;54(6):1422-4.
1994: van der Riet P; Nawroz H; Hruban R H; Corio R; Tokino K; Koch W; Sidransky D
Frequent loss of chromosome 9p21-22 early in head and neck cancer progression.
Cancer research 1994;54(5):1156-8.
1994: Nawroz H; van der Riet P; Hruban R H; Koch W; Ruppert J M; Sidransky D
Allelotype of head and neck squamous cell carcinoma.
Cancer research 1994;54(5):1152-5.
1994: Mao L; Sidransky D
Tetranucleotide repeat polymorphism in RAF1.
Human molecular genetics 1994;3(3):521.
1994: Merlo A; Gabrielson E; Askin F; Sidransky D
Frequent loss of chromosome 9 in human primary non-small cell lung cancer.
Cancer research 1994;54(3):640-2.
1994: van der Riet P; Karp D; Farmer E; Wei Q; Grossman L; Tokino K; Ruppert J M; Sidransky D
Progression of basal cell carcinoma through loss of chromosome 9q and inactivation of a single p53 allele.
Cancer research 1994;54(1):25-7.
1993: Ruppert J M; Tokino K; Sidransky D
Evidence for two bladder cancer suppressor loci on human chromosome 9.
Cancer research 1993;53(21):5093-5.
1993: Sidransky D; Boyle J; Koch W
Molecular screening. Prospects for a new approach.
Archives of otolaryngology--head & neck surgery 1993;119(11):1187-90.
1993: Boyle J O; Hakim J; Koch W; van der Riet P; Hruban R H; Roa R A; Correo R; Eby Y J; Ruppert J M; Sidransky D
The incidence of p53 mutations increases with progression of head and neck cancer.
Cancer research 1993;53(19):4477-80.
1993: Leach F S; Tokino T; Meltzer P; Burrell M; Oliner J D; Smith S; Hill D E; Sidransky D; Kinzler K W; Vogelstein B
p53 Mutation and MDM2 amplification in human soft tissue sarcomas.
Cancer research 1993;53(10 Suppl):2231-4.
1993: Celano P; Berchtold C M; Mabry M; Carroll M; Sidransky D; Casero R A; Lupu R
Induction of markers of normal differentiation in human colon carcinoma cells by the v-rasH oncogene.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1993;4(4):341-7.
1993: Sidransky D; Boyle J; Koch W; van der Riet P
Oncogene mutations as intermediate markers.
Journal of cellular biochemistry. Supplement 1993;17F():184-7.
1992: Sidransky D; Messing E
Molecular genetics and biochemical mechanisms in bladder cancer. Oncogenes, tumor suppressor genes, and growth factors.
The Urologic clinics of North America 1992;19(4):629-39.
1992: Sidransky D; Tokino T; Helzlsouer K; Zehnbauer B; Rausch G; Shelton B; Prestigiacomo L; Vogelstein B; Davidson N
Inherited p53 gene mutations in breast cancer.
Cancer research 1992;52(10):2984-6.
1992: Sidransky D; Tokino T; Hamilton S R; Kinzler K W; Levin B; Frost P; Vogelstein B
Identification of ras oncogene mutations in the stool of patients with curable colorectal tumors.
Science (New York, N.Y.) 1992;256(5053):102-5.
1992: Bennett W P; Hollstein M C; Hsu I C; Sidransky D; Lane D P; Vogelstein B; Harris C C
Mutational spectra and immunohistochemical analyses of p53 in human cancers.
Chest 1992;101(3 Suppl):19S-20S.
1992: Sidransky D; Frost P; Von Eschenbach A; Oyasu R; Preisinger A C; Vogelstein B
Clonal origin bladder cancer.
The New England journal of medicine 1992;326(11):737-40.
1992: Sidransky D; Mikkelsen T; Schwechheimer K; Rosenblum M L; Cavanee W; Vogelstein B
Clonal expansion of p53 mutant cells is associated with brain tumour progression.
Nature 1992;355(6363):846-7.
1991: Kastan M B; Onyekwere O; Sidransky D; Vogelstein B; Craig R W
Participation of p53 protein in the cellular response to DNA damage.
Cancer research 1991;51(23 Pt 1):6304-11.
1991: Saylors R L; Sidransky D; Friedman H S; Bigner S H; Bigner D D; Vogelstein B; Brodeur G M
Infrequent p53 gene mutations in medulloblastomas.
Cancer research 1991;51(17):4721-3.
1991: Hollstein M; Sidransky D; Vogelstein B; Harris C C
p53 mutations in human cancers.
Science (New York, N.Y.) 1991;253(5015):49-53.
1991: Sidransky D; Von Eschenbach A; Tsai Y C; Jones P; Summerhayes I; Marshall F; Paul M; Green P; Hamilton S R; Frost P
Identification of p53 gene mutations in bladder cancers and urine samples.
Science (New York, N.Y.) 1991;252(5006):706-9.

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