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Gary Sieckman
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Research Profile (preview)
Chemicals & Drugs
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Network (preview)
25
Hoffman, Timothy
18
Volkert, Wynn
10
Rold, Tammy
10
Gali, Hariprasad
9
Owen, Nellie
8
Figueroa, Said Daibes
7
Forte, Leonard
7
Smith, Charles
5
Smith, Jeffrey
5
Prasanphanich, Adam
4
Veerendra, Bhadrasetty
4
Ma, Lixin
4
Mazuru, Dana
4
Garrison, Jered
4
Giblin, Michael
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Publications
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All Publications
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2009: Prasanphanich Adam F; Retzloff Lauren; Lane Stephanie R; Nanda Prasant K; Sieckman Gary L; Rold Tammy L; Ma Lixin; Figueroa Said D; Sublett Samantha V; Hoffman Timothy J; Smith Charles J
In vitro and in vivo analysis of [(64)Cu-NO2A-8-Aoc-BBN(7-14)NH(2)]: a site-directed radiopharmaceutical for positron-emission tomography imaging of T-47D human breast cancer tumors.
Nuclear medicine and biology 2009;36(2):171-81.
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2008: Abd-Elgaliel Wael R; Gallazzi Fabio; Garrison Jered C; Rold Tammy L; Sieckman Gary L; Figueroa Said Daibes; Hoffman Timothy J; Lever Susan Z
Design, synthesis, and biological evaluation of an antagonist-bombesin analogue as targeting vector.
Bioconjugate chemistry 2008;19(10):2040-8.
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2008: Garrison Jered C; Rold Tammy L; Sieckman Gary L; Naz Farah; Sublett Samantha V; Figueroa Said Daibes; Volkert Wynn A; Hoffman Timothy J
Evaluation of the pharmacokinetic effects of various linking group using the 111In-DOTA-X-BBN(7-14)NH2 structural paradigm in a prostate cancer model.
Bioconjugate chemistry 2008;19(9):1803-12.
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2008: Lane Stephanie R; Veerendra Bhadrasetty; Rold Tammy L; Sieckman Gary L; Hoffman Timothy J; Jurisson Silvia S; Smith Charles J
99mTc(CO)3-DTMA bombesin conjugates having high affinity for the GRP receptor.
Nuclear medicine and biology 2008;35(3):263-72.
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2007: Kunstler Jens-Uwe; Veerendra Bhadrasetty; Figueroa Said D; Sieckman Gary L; Rold Tammy L; Hoffman Timothy J; Smith Charles J; Pietzsch Hans-Jurgen
Organometallic 99mTc(III) '4 + 1' bombesin(7-14) conjugates: synthesis, radiolabeling, and in vitro/in vivo studies.
Bioconjugate chemistry 2007;18(5):1651-61.
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2007: Garrison Jered C; Rold Tammy L; Sieckman Gary L; Figueroa Said Daibes; Volkert Wynn A; Jurisson Silvia S; Hoffman Timothy J
In vivo evaluation and small-animal PET/CT of a prostate cancer mouse model using 64Cu bombesin analogs: side-by-side comparison of the CB-TE2A and DOTA chelation systems.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2007;48(8):1327-37.
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2007: Prasanphanich Adam F; Nanda Prasant K; Rold Tammy L; Ma Lixin; Lewis Michael R; Garrison Jered C; Hoffman Timothy J; Sieckman Gary L; Figueroa Said D; Smith Charles J
[64Cu-NOTA-8-Aoc-BBN(7-14)NH2] targeting vector for positron-emission tomography imaging of gastrin-releasing peptide receptor-expressing tissues.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(30):12462-7.
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2007: Ma Lixin; Yu Ping; Veerendra Bhadrasetty; Rold Tammy L; Retzloff Lauren; Prasanphanich Adam; Sieckman Gary; Hoffman Timothy J; Volkert Wynn A; Smith Charles J
In vitro and in vivo evaluation of Alexa Fluor 680-bombesin[7-14]NH2 peptide conjugate, a high-affinity fluorescent probe with high selectivity for the gastrin-releasing peptide receptor.
Molecular imaging : official journal of the Society for Molecular Imaging 2007;6(3):171-80.
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2007: Prasanphanich Adam F; Lane Stephanie R; Figueroa Said D; Ma Lixin; Rold Tammy L; Sieckman Gary L; Hoffman Timothy J; McCrate Joseph M; Smith Charles J
The effects of linking substituents on the in vivo behavior of site-directed, peptide-based, diagnostic radiopharmaceuticals.
In vivo (Athens, Greece) 2007;21(1):1-16.
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2006: Giblin Michael F; Sieckman Gary L; Watkinson Lisa D; Daibes-Figueroa Said; Hoffman Timothy J; Forte Leonard R; Volkert Wynn A
Selective targeting of E. coli heat-stable enterotoxin analogs to human colon cancer cells.
Anticancer research 2006;26(5A):3243-51.
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2006: Alves Susana; Correia Joao D G; Santos Isabel; Veerendra Bhadrasetty; Sieckman Gary L; Hoffman Timothy J; Rold Tammy L; Figueroa Said Daibes; Retzloff Lauren; McCrate Joseph; Prasanphanich Adam; Smith Charles J
Pyrazolyl conjugates of bombesin: a new tridentate ligand framework for the stabilization of fac-[M(CO)3]+ moiety.
Nuclear medicine and biology 2006;33(5):625-34.
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2006: Giblin Michael F; Gali Hariprasad; Sieckman Gary L; Owen Nellie K; Hoffman Timothy J; Volkert Wynn A; Forte Leonard R
In vitro and in vivo evaluation of 111In-labeled E. coli heat-stable enterotoxin analogs for specific targeting of human breast cancers.
Breast cancer research and treatment 2006;98(1):7-15.
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2006: Giblin Michael F; Sieckman Gary L; Shelton Tiffani D; Hoffman Timothy J; Forte Leonard R; Volkert Wynn A
In vitro and in vivo evaluation of 177Lu- and 90Y-labeled E. coli heat-stable enterotoxin for specific targeting of uroguanylin receptors on human colon cancers.
Nuclear medicine and biology 2006;33(4):481-8.
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2004: Giblin Michael F; Gali Hariprasad; Sieckman Gary L; Owen Nellie K; Hoffman Timothy J; Forte Leonard R; Volkert Wynn A
In vitro and in vivo comparison of human Escherichia coli heat-stable peptide analogues incorporating the 111In-DOTA group and distinct linker moieties.
Bioconjugate chemistry 2004;15(4):872-80.
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2003: Smith C Jeffrey; Sieckman Gary L; Owen Nellie K; Hayes Donald L; Mazuru Dana G; Kannan Raghuraman; Volkert Wynn A; Hoffman Timothy J
Radiochemical investigations of gastrin-releasing peptide receptor-specific [(99m)Tc(X)(CO)3-Dpr-Ser-Ser-Ser-Gln-Trp-Ala-Val-Gly-His-Leu-Met-(NH2)] in PC-3, tumor-bearing, rodent models: syntheses, radiolabeling, and in vitro/in vivo studies where Dpr = 2,3-diaminopropionic acid and X = H2O or P(CH2OH)3.
Cancer research 2003;63(14):4082-8.
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2003: Hoffman Timothy J; Gali Hariprasad; Smith C Jeffrey; Sieckman Gary L; Hayes Donald L; Owen Nellie K; Volkert Wynn A
Novel series of 111In-labeled bombesin analogs as potential radiopharmaceuticals for specific targeting of gastrin-releasing peptide receptors expressed on human prostate cancer cells.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2003;44(5):823-31.
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2003: Smith C Jeffrey; Gali Hariprasad; Sieckman Gary L; Hayes Donald L; Owen Nellie K; Mazuru Dana G; Volkert Wynn A; Hoffman Timothy J
Radiochemical investigations of 177Lu-DOTA-8-Aoc-BBN[7-14]NH2: an in vitro/in vivo assessment of the targeting ability of this new radiopharmaceutical for PC-3 human prostate cancer cells.
Nuclear medicine and biology 2003;30(2):101-9.
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2003: Smith C Jeffrey; Sieckman Gary L; Owen Nellie K; Hayes Donald L; Mazuru Dana G; Volkert Wynn A; Hoffman Timothy J
Radiochemical investigations of [188Re(H2O)(CO)3-diaminopropionic acid-SSS-bombesin(7-14)NH2]: syntheses, radiolabeling and in vitro/in vivo GRP receptor targeting studies.
Anticancer research 2003;23(1A):63-70.
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2003: Smith C Jeffrey; Gali Hariprasad; Sieckman Gary L; Higginbotham Chris; Volkert Wynn A; Hoffman Timothy J
Radiochemical investigations of (99m)Tc-N(3)S-X-BBN[7-14]NH(2): an in vitro/in vivo structure-activity relationship study where X = 0-, 3-, 5-, 8-, and 11-carbon tethering moieties.
Bioconjugate chemistry 2003;14(1):93-102.
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2002: Hu Fang; Cutler Cathy S; Hoffman Timothy; Sieckman Gary; Volkert Wynn A; Jurisson Silvia S
Pm-149 DOTA bombesin analogs for potential radiotherapy. in vivo comparison with Sm-153 and Lu-177 labeled DO3A-amide-betaAla-BBN(7-14)NH(2).
Nuclear medicine and biology 2002;29(4):423-30.
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2002: Gali Hariprasad; Sieckman Gary L; Hoffman Timothy J; Owen Nellie K; Mazuru Dana G; Forte Leonard R; Volkert Wynn A
Chemical synthesis of Escherichia coli ST(h) analogues by regioselective disulfide bond formation: biological evaluation of an (111)In-DOTA-Phe(19)-ST(h) analogue for specific targeting of human colon cancers.
Bioconjugate chemistry 2002;13(2):224-31.
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2001: Gali H; Sieckman G L; Hoffman T J; Owen N K; Chin D T; Forte L R; Volkert W A
In vivo evaluation of an 111In-labeled ST-peptide analog for specific-targeting of human colon cancers.
Nuclear medicine and biology 2001;28(8):903-9.
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2001: Gali H; Sieckman G L; Hoffman T J; Kiefer G E; Chin D T; Forte L R; Volkert W A
Synthesis and in vitro evaluation of an 111In-labeled ST-peptide enterotoxin (ST) analogue for specific targeting of guanylin receptors on human colonic cancers.
Anticancer research 2001;21(4A):2785-92.
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2001: Gali H; Hoffman T J; Sieckman G L; Owen N K; Katti K V; Volkert W A
Synthesis, characterization, and labeling with 99mTc/188Re of peptide conjugates containing a dithia-bisphosphine chelating agent.
Bioconjugate chemistry 2001;12(3):354-63.
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1999: Karra S R; Schibli R; Gali H; Katti K V; Hoffman T J; Higginbotham C; Sieckman G L; Volkert W A
99mTc-labeling and in vivo studies of a bombesin analogue with a novel water-soluble dithiadiphosphine-based bifunctional chelating agent.
Bioconjugate chemistry 1999;10(2):254-60.
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