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Michael Boarder

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Somchaiya Surichan; Aristidis Tsatsakis; Vasilis P Androutsopoulos; Randolph R J Arroo; Eleni Koutala; Stavros Sifakis; Michael R Boarder
Bioactivation of the citrus flavonoid nobiletin by CYP1 enzymes in MCF7 breast adenocarcinoma cells.
Yi Luo; Zhong Cheng; C Jane Dixon; John F Hall; Emma Taylor; Michael R Boarder
Endosomal signalling of epidermal growth factor receptors contributes to EGF-stimulated cell cycle progression in primary hepatocytes.
Cristina Sena; Elsa Nunes; T Louro; Teresa Proença; R Fernandes; Michael R Boarder; Raquel Seiça
Effects of alpha-lipoic acid on endothelial function in aged diabetic and high-fat fed rats.

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All Publications

2012: Somchaiya Surichan; Aristidis Tsatsakis; Vasilis P Androutsopoulos; Randolph R J Arroo; Eleni Koutala; Stavros Sifakis; Michael R Boarder
Bioactivation of the citrus flavonoid nobiletin by CYP1 enzymes in MCF7 breast adenocarcinoma cells.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 2012;50(9):3320-8.
2011: Yi Luo; Zhong Cheng; C Jane Dixon; John F Hall; Emma Taylor; Michael R Boarder
Endosomal signalling of epidermal growth factor receptors contributes to EGF-stimulated cell cycle progression in primary hepatocytes.
European journal of pharmacology 2011;654(2):173-80.
2008: Cristina Sena; Elsa Nunes; T Louro; Teresa Proença; R Fernandes; Michael R Boarder; Raquel Seiça
Effects of alpha-lipoic acid on endothelial function in aged diabetic and high-fat fed rats.
British journal of pharmacology 2008;153(5):894-906.
2007: Yi Luo; C Jane Dixon; John F Hall; Pamela J White; Michael R Boarder
A role for Akt in epidermal growth factor-stimulated cell cycle progression in cultured hepatocytes: generation of a hyperproliferative window after adenoviral expression of constitutively active Akt.
The Journal of pharmacology and experimental therapeutics 2007;321(3):884-91.
2005: C Jane Dixon; Pamela J White; John F Hall; Shaun Kingston; Michael R Boarder
Regulation of human hepatocytes by P2Y receptors: control of glycogen phosphorylase, Ca2+, and mitogen-activated protein kinases.
The Journal of pharmacology and experimental therapeutics 2005;313(3):1305-13.
2004: C Jane Dixon; John F Hall; Tania E Webb; Michael R Boarder
Regulation of rat hepatocyte function by P2Y receptors: focus on control of glycogen phosphorylase and cyclic AMP by 2-methylthioadenosine 5'-diphosphate.
The Journal of pharmacology and experimental therapeutics 2004;311(1):334-41.
2003: Rajendra Kumari; Gareth Goh; Leong L Ng; Michael R Boarder
ATP and UTP responses of cultured rat aortic smooth muscle cells revisited: dominance of P2Y2 receptors.
British journal of pharmacology 2003;140(7):1169-76.
2003: Pamela J White; Tania E Webb; Michael R Boarder
Characterization of a Ca2+ response to both UTP and ATP at human P2Y11 receptors: evidence for agonist-specific signaling.
Molecular pharmacology 2003;63(6):1356-63.
2003: Gillian C Bennett; Anthony P D W Ford; Jacqueline A M Smith; Caroline J Emmett; Tania E Webb; Michael R Boarder
P2Y receptor regulation of cultured rat cerebral cortical cells: calcium responses and mRNA expression in neurons and glia.
British journal of pharmacology 2003;139(2):279-88.
2003: C Jane Dixon; John F Hall; Michael R Boarder
ADP stimulation of inositol phosphates in hepatocytes: role of conversion to ATP and stimulation of P2Y2 receptors.
British journal of pharmacology 2003;138(1):272-8.
2000: Pamela J White; R Kumari; K E Porter; N J London; Leong L Ng; Michael R Boarder
Antiproliferative effect of UTP on human arterial and venous smooth muscle cells.
American journal of physiology. Heart and circulatory physiology 2000;279(6):H2735-42.
2000: G C Bennett; Michael R Boarder
The effect of nucleotides and adenosine on stimulus-evoked glutamate release from rat brain cortical slices.
British journal of pharmacology 2000;131(3):617-23.
1999: Z Anwar; J L Albert; S E Gubby; JP Boyle; J A Roberts; Tania E Webb; Michael R Boarder
Regulation of cyclic AMP by extracellular ATP in cultured brain capillary endothelial cells.
British journal of pharmacology 1999;128(2):465-71.
1998: S Harper; Tania E Webb; Steven J Charlton; Leong L Ng; Michael R Boarder
Evidence that P2Y4 nucleotide receptors are involved in the regulation of rat aortic smooth muscle cells by UTP and ATP.
British journal of pharmacology 1998;124(4):703-10.
1998: Michael R Boarder; S M Hourani
The regulation of vascular function by P2 receptors: multiple sites and multiple receptors.
Trends in pharmacological sciences 1998;19(3):99-107.
1997: J L Albert; JP Boyle; J A Roberts; R A John Challiss; S E Gubby; Michael R Boarder
Regulation of brain capillary endothelial cells by P2Y receptors coupled to Ca2+, phospholipase C and mitogen-activated protein kinase.
British journal of pharmacology 1997;122(5):935-41.
1997: N Wilkie; Leong L Ng; Michael R Boarder
Angiotensin II responses of vascular smooth muscle cells from hypertensive rats: enhancement at the level of p42 and p44 mitogen activated protein kinase.
British journal of pharmacology 1997;122(2):209-16.
1997: C A Brown; Steven J Charlton; Michael R Boarder
Enhancement of the response to purinergic agonists in P2Y1 transfected 1321N1 cells by antagonists suramin and PPADS.
British journal of pharmacology 1997;120(6):1049-52.
1996: C A Brown; V Patel; G Wilkinson; Michael R Boarder
P2 purinoceptor-stimulated conversion of arginine to citrulline in bovine endothelial cells is reduced by inhibition of protein kinase C.
Biochemical pharmacology 1996;52(12):1849-54.
1996: N Wilkie; C Morton; Leong L Ng; Michael R Boarder
Stimulated mitogen-activated protein kinase is necessary but not sufficient for the mitogenic response to angiotensin II. A role for phospholipase D.
The Journal of biological chemistry 1996;271(50):32447-53.
1996: Steven J Charlton; C A Brown; Gary A Weisman; John T Turner; Laurie Erb; Michael R Boarder
Cloned and transfected P2Y4 receptors: characterization of a suramin and PPADS-insensitive response to UTP.
British journal of pharmacology 1996;119(7):1301-3.
1996: V Patel; C Brown; A Goodwin; N Wilkie; Michael R Boarder
Phosphorylation and activation of p42 and p44 mitogen-activated protein kinase are required for the P2 purinoceptor stimulation of endothelial prostacyclin production.
The Biochemical journal 1996;320 ( Pt 1)():221-6.
1996: Steven J Charlton; C A Brown; Gary A Weisman; John T Turner; Laurie Erb; Michael R Boarder
PPADS and suramin as antagonists at cloned P2Y- and P2U-purinoceptors.
British journal of pharmacology 1996;118(3):704-10.
1996: V Patel; C Brown; Michael R Boarder
Protein kinase C isoforms in bovine aortic endothelial cells: role in regulation of P2Y- and P2U-purinoceptor-stimulated prostacyclin release.
British journal of pharmacology 1996;118(1):123-30.
1996: C M Sena; Luís M Rosário; P J Parker; V Patel; Michael R Boarder
Differential regulation of histamine- and bradykinin-stimulated phospholipase C in adrenal chromaffin cells: evidence for involvement of different protein kinase C isoforms.
Journal of neurochemistry 1996;66(3):1086-94.
1996: N Wilkie; Leong L Ng; Michael R Boarder
Vascular smooth muscle cells from spontaneously hypertensive rats exhibit increased MAPK response to angiotensin II and phorbol ester stimulation.
Biochemical Society transactions 1996;24(1):65S.
1996: V Patel; C Brown; Michael R Boarder
Protein kinase C isoforms in endothelial cells: role in agonist stimulated prostacyclin release.
Biochemical Society transactions 1996;24(1):56S.
1996: C A Brown; A Bowden; V Patel; Michael R Boarder
Stimulation of prostacyclin release by endothelial ATP receptors requires activation of protein kinase C and tyrosine kinases.
Biochemical Society transactions 1996;24(1):55S.
1995: A Bowden; V Patel; C Brown; Michael R Boarder
Evidence for requirement of tyrosine phosphorylation in endothelial P2Y- and P2U- purinoceptor stimulation of prostacyclin release.
British journal of pharmacology 1995;116(6):2563-8.
1995: C Brown; B Tanna; Michael R Boarder
PPADS: an antagonist at endothelial P2Y-purinoceptors but not P2U-purinoceptors.
British journal of pharmacology 1995;116(5):2413-6.
1995: C Morton; N Wilkie; Michael R Boarder
Tyrosine phosphorylation, MAPK and PLD in AII stimulated mitogenesis.
Biochemical Society transactions 1995;23(3):426S.
1995: C A Brown; G F Wilkinson; Michael R Boarder
Stimulation of nitric oxide synthase by endothelial purinoceptors does not correlate with inositol trisphosphate levels.
Biochemical Society transactions 1995;23(3):425S.
1995: Michael R Boarder; C M Sena; P J Parker; V Patel; L M Rosario
Regulation of bradykinin responses by PKC epsilon and histamine responses by PKC alpha in adrenal chromaffin cells.
Biochemical Society transactions 1995;23(3):424S.
1995: G F Wilkinson; Michael R Boarder
Binding of [35S]adenosine 5'-O-(2-thiodiphosphate) to endothelial cells in culture.
Biochemical pharmacology 1995;49(10):1411-8.
1995: C Morton; R Baines; I Masood; L Ng; Michael R Boarder
Stimulation of two vascular smooth muscle-derived cell lines by angiotensin II: differential second messenger responses leading to mitogenesis.
British journal of pharmacology 1995;115(2):361-7.
1995: Michael R Boarder; Gary A Weisman; John T Turner; G F Wilkinson
G protein-coupled P2 purinoceptors: from molecular biology to functional responses.
Trends in pharmacological sciences 1995;16(4):133-9.
1995: Michael R Boarder; J R Purkiss
Measurement of diacylglycerol. Origins of receptor-stimulated diacylglycerol accumulation.
Methods in molecular biology (Clifton, N.J.) 1995;41():189-202.
1994: Michael R Boarder; John T Turner; Laurie Erb; Gary A Weisman
Classification of P2 purinoceptors. Not all G protein-coupled P2 purinoceptors can be classed as P2Y.
Trends in pharmacological sciences 1994;15(8):280-1.
1994: G F Wilkinson; J R Purkiss; Michael R Boarder
Differential heterologous and homologous desensitization of two receptors for ATP (P2y purinoceptors and nucleotide receptors) coexisting on endothelial cells.
Molecular pharmacology 1994;45(4):731-6.
1994: J R Purkiss; D West; L C Wilkes; C Scott; P Yarrow; G F Wilkinson; Michael R Boarder
Stimulation of phospholipase C in cultured microvascular endothelial cells from human frontal lobe by histamine, endothelin and purinoceptor agonists.
British journal of pharmacology 1994;111(4):1041-6.
1994: J R Purkiss; G F Wilkinson; Michael R Boarder
Differential regulation of inositol 1,4,5-trisphosphate by co-existing P2Y-purinoceptors and nucleotide receptors on bovine aortic endothelial cells.
British journal of pharmacology 1994;111(3):723-8.
1994: Michael R Boarder
A role for phospholipase D in control of mitogenesis.
Trends in pharmacological sciences 1994;15(2):57-62.
1994: G F Wilkinson; K McKechnie; I A Dainty; Michael R Boarder
P2Y purinoceptor and nucleotide receptor-induced relaxation of precontracted bovine aortic collateral artery rings: differential sensitivity to suramin and indomethacin.
The Journal of pharmacology and experimental therapeutics 1994;268(2):881-7.
1993: R A John Challiss; L C Wilkes; V Patel; J R Purkiss; Michael R Boarder
Phospholipase D activation regulates endothelin-1 stimulation of phosphoinositide-specific phospholipase C in SK-N-MC cells.
FEBS letters 1993;327(2):157-60.
1993: L C Wilkes; V Patel; J R Purkiss; Michael R Boarder
Endothelin-1 stimulated phospholipase D in A10 vascular smooth muscle derived cells is dependent on tyrosine kinase. Evidence for involvement in stimulation of mitogenesis.
FEBS letters 1993;322(2):147-50.
1993: J R Purkiss; G F Wilkinson; Michael R Boarder
Evidence for a nucleotide receptor on adrenal medullary endothelial cells linked to phospholipase C and phospholipase D.
British journal of pharmacology 1993;108(4):1031-7.
1993: G F Wilkinson; J R Purkiss; Michael R Boarder
The regulation of aortic endothelial cells by purines and pyrimidines involves co-existing P2y-purinoceptors and nucleotide receptors linked to phospholipase C.
British journal of pharmacology 1993;108(3):689-93.
1992: Michael R Boarder; R A John Challiss
Role of protein kinase C in the regulation of histamine and bradykinin stimulated inositol polyphosphate turnover in adrenal chromaffin cells.
British journal of pharmacology 1992;107(4):1140-5.
1992: J R Purkiss; Michael R Boarder
Stimulation of phosphatidate synthesis in endothelial cells in response to P2-receptor activation. Evidence for phospholipase C and phospholipase D involvement, phosphatidate and diacylglycerol interconversion and the role of protein kinase C.
The Biochemical journal 1992;287 ( Pt 1)():31-6.
1992: J R Purkiss; Michael R Boarder
Purinergic stimulation of phosphatidic acid accumulation is via two pathways in bovine aorta endothelial cells.
Biochemical Society transactions 1992;20(2):141S.
1992: L C Wilkes; Michael R Boarder
Evidence for a novel mechanism of activation of phospholipase D by endothelin-1 in neuroblastoma cells.
Biochemical Society transactions 1992;20(2):130S.
1992: J Purkiss; P J Owen; Jeffrey A Jones; Michael R Boarder
Stimulation of phosphatidic acid synthesis in bovine aortic endothelial cells in response to activation of P2-purinergic receptors.
Biochemical pharmacology 1992;43(6):1235-42.
1992: R J Murrin; Michael R Boarder
Neuronal "nucleotide" receptor linked to phospholipase C and phospholipase D? Stimulation of PC12 cells by ATP analogues and UTP.
Molecular pharmacology 1992;41(3):561-8.
1991: L C Wilkes; Michael R Boarder
Characterization of endothelin receptors on a human neuroblastoma cell line: evidence for the ETA subtype.
British journal of pharmacology 1991;104(3):750-4.
1991: P J Owen; Jeffrey A Jones; Michael R Boarder
Phosphatidic acid accumulation and catecholamine release in adrenal chromaffin cells: stimulation by high potassium and by nicotine, and effect of a diacylglycerol kinase inhibitor R 59 022.
Journal of neurochemistry 1991;57(3):769-74.
1991: P J Owen; Michael R Boarder
Influence of bradykinin on diacylglycerol and phosphatidic acid accumulation in cultured bovine adrenal chromaffin cells.
Journal of neurochemistry 1991;57(3):760-8.
1991: J Purkiss; R A Murrin; P J Owen; Michael R Boarder
Lack of phospholipase D activity in chromaffin cells: bradykinin-stimulated phosphatidic acid formation involves phospholipase C in chromaffin cells but phospholipase D in PC12 cells.
Journal of neurochemistry 1991;57(3):1084-7.
1991: R A Challis; J A Jones; P J Owen; Michael R Boarder
Changes in inositol 1,4,5-trisphosphate and inositol 1,3,4,5- tetrakisphosphate mass accumulations in cultured adrenal chromaffin cells in response to bradykinin and histamine.
Journal of neurochemistry 1991;56(3):1083-6.
1991: Michael R Boarder; D B Marriott
Endothelin-1 stimulation of noradrenaline and adrenaline release from adrenal chromaffin cells.
Biochemical pharmacology 1991;41(4):521-6.
1991: L C Wilkes; Michael R Boarder
Characterization of the endothelin binding site on bovine adrenomedullary chromaffin cells: comparison with vascular smooth muscle cells. Evidence for receptor heterogeneity.
The Journal of pharmacology and experimental therapeutics 1991;256(2):628-33.
1990: J A Jones; P J Owen; Michael R Boarder
Influence of phorbol esters, and diacylglycerol kinase and lipase inhibitors on noradrenaline release and phosphoinositide hydrolysis in chromaffin cells.
British journal of pharmacology 1990;101(3):521-6.
1990: D J Allsup; Michael R Boarder
Comparison of P2 purinergic receptors of aortic endothelial cells with those of adrenal medulla: evidence for heterogeneity of receptor subtype and of inositol phosphate response.
Molecular pharmacology 1990;38(1):84-91.
1990: R Plevin; P J Owen; D B Marriott; J A Jones; Michael R Boarder
Role of phosphoinositide turnover and cyclic AMP accumulation in prostaglandin-stimulated noradrenaline release from cultured adrenal chromaffin cells.
The Journal of pharmacology and experimental therapeutics 1990;252(3):1296-303.
1989: D J Allsup; Michael R Boarder
Comparison of P2 receptors of aortic endothelial cells with those of adrenal medulla non-chromaffin cells.
British journal of pharmacology 1989;98 Suppl():795P.
1989: Michael R Boarder
Presynaptic aspects of cotransmission: relationship between vesicles and neurotransmitters.
Journal of neurochemistry 1989;53(1):1-11.
1989: P J Owen; D B Marriott; Michael R Boarder
Evidence for a dihydropyridine-sensitive and conotoxin-insensitive release of noradrenaline and uptake of calcium in adrenal chromaffin cells.
British journal of pharmacology 1989;97(1):133-8.
1989: P J Owen; R Plevin; Michael R Boarder
Characterization of bradykinin-stimulated release of noradrenaline from cultured bovine adrenal chromaffin cells.
The Journal of pharmacology and experimental therapeutics 1989;248(3):1231-6.
1989: Michael R Boarder; D B Marriott
Characterization of endothelin-1 stimulation of catecholamine release from adrenal chromaffin cells.
Journal of cardiovascular pharmacology 1989;13 Suppl 5():S223-4.
1988: Michael R Boarder; R Plevin; D B Marriott
Angiotensin II potentiates prostaglandin stimulation of cyclic AMP levels in intact bovine adrenal medulla cells but not adenylate cyclase in permeabilized cells.
The Journal of biological chemistry 1988;263(30):15319-24.
1988: R Plevin; Michael R Boarder
Stimulation of formation of inositol phosphates in primary cultures of bovine adrenal chromaffin cells by angiotensin II, histamine, bradykinin, and carbachol.
Journal of neurochemistry 1988;51(2):634-41.
1988: D Marriott; M Adams; Michael R Boarder
Effect of forskolin and prostaglandin E1 on stimulus secretion coupling in cultured bovine adrenal chromaffin cells.
Journal of neurochemistry 1988;50(2):616-23.
1987: Michael R Boarder; C Evans; M Adams; E Erdelyi; J D Barchas
Peptide E and its products, BAM 18 and Leu-enkephalin, in bovine adrenal medulla and cultured chromaffin cells: release in response to stimulation.
Journal of neurochemistry 1987;49(6):1824-32.
1983: Michael R Boarder; E Weber; C J Evans; E Erdelyi; J Barchas
Measurement of total opioid peptides in rat brain and pituitary by radioimmunoassay directed at the alpha-N-acetyl derivative.
Journal of neurochemistry 1983;40(6):1517-22.
1982: Michael R Boarder; E Erdelyi; J D Barchas
Opioid peptides in human plasma: evidence for multiple forms.
The Journal of clinical endocrinology and metabolism 1982;54(4):715-20.
1982: Michael R Boarder; E Erdelyi; J D Barchas
Forms of opioid peptides circulating in human blood: investigation with multiple radioimmunoassays and radioreceptor assay.
Advances in biochemical psychopharmacology 1982;33():117-22.
1981: Michael R Boarder; E Erdelyi; J D Barchas
Synthetic N-dimethyl beta-endorphin, a stabilized opioid peptide.
Biochemical pharmacology 1981;30(11):1289-93.