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Gene Siegal

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TOP 3
Christopher Kragel; Gene P Siegal; Shi Wei
Epiphyseal chondromyxoid fibroma with prominent adipose tissue: an unusual radiologic and histologic presentation.
Paul G Daft; Michael J Klein; Gene P Siegal; Jason M Warram; Kaiyu Yuan; Majd zayzafoon
Alpha-CaMKII Plays a Critical Role in Determining the Aggressive Behavior of Human Osteosarcoma.
James J Cody; Jason W Ashley; Xu Feng; Gray R Lyons; Sreelatha Meleth; Angel A Rivera; Gene P Siegal; Minghui Wang; Sherry W Yang; Joanne T Douglas
Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model.

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All Publications

2013: Christopher Kragel; Gene P Siegal; Shi Wei
Epiphyseal chondromyxoid fibroma with prominent adipose tissue: an unusual radiologic and histologic presentation.
American journal of orthopedics (Belle Mead, N.J.) 2013;42(4):175-8.
2013: Paul G Daft; Michael J Klein; Gene P Siegal; Jason M Warram; Kaiyu Yuan; Majd zayzafoon
Alpha-CaMKII Plays a Critical Role in Determining the Aggressive Behavior of Human Osteosarcoma.
Molecular cancer research : MCR 2013;11(4):349-59.
2013: James J Cody; Jason W Ashley; Xu Feng; Gray R Lyons; Sreelatha Meleth; Angel A Rivera; Gene P Siegal; Minghui Wang; Sherry W Yang; Joanne T Douglas
Expression of osteoprotegerin from a replicating adenovirus inhibits the progression of prostate cancer bone metastases in a murine model.
Laboratory investigation; a journal of technical methods and pathology 2013;93(3):268-78.
2013: Jay J Listinsky; Gene P Siegal; Catherine M Listinsky
Glycoengineering in cancer therapeutics: a review with fucose-depleted trastuzumab as the model.
Anti-cancer drugs 2013;24(3):219-27.
2013: Scott C Borinstein; Richard Gorlick; Patrick Grohar; Paul Jedlicka; Mark Krailo; Elizabeth R Lawlor; Stephen L Lessnick; Carol Morris; Sharon Phillips; Gene P Siegal; Natalie Beeler; John J Block
A Decade in Banking Ewing Sarcoma: A Report from the Children's Oncology Group.
Frontiers in oncology 2013;3():57.
2012: Rong Li; David Kelly; Gene P Siegal
Bilateral mesenchymal hamartoma of the chest wall in an infant boy.
Fetal and pediatric pathology 2012;31(6):415-22.
2012: Robert N Bone; Wanxing Cui; Mert Icyuz; Qiana L Matthews; Ji-Bin Peng; Gene P Siegal; Hongjun Wang; Yanqing Zhang; Yuan Zhang; Hongju Wu
Gene transfer of active Akt1 by an infectivity-enhanced adenovirus impacts β-cell survival and proliferation differentially in vitro and in vivo.
Islets 2012;4(6):366-78.
2012: Anandi Sawant; Gene P Siegal; Diptiman Chanda; Brittney A Harris; Jonathan A Hensel; Akhil Maheshwari; Selvarangan Ponnazhagan
Depletion of plasmacytoid dendritic cells inhibits tumor growth and prevents bone metastasis of breast cancer cells.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(9):4258-65.
2012: Samuel Borak; Nirag Jhala; Vishnu Reddy; Gene P Siegal; Darshana Jhala
Metastatic inflammatory myofibroblastic tumor identified by EUS-FNA in mediastinal lymph nodes with ancillary FISH studies for ALK rearrangement.
Diagnostic cytopathology 2012;40 Suppl 2():E118-25.
2012: Gabriel Rezonzew; Gene P Siegal; Phillip Chumley; Wenguang Feng; Ping Hua; Edgar A Jaimes
Nicotine exposure and the progression of chronic kidney disease: role of the α7-nicotinic acetylcholine receptor.
American journal of physiology. Renal physiology 2012;303(2):F304-12.
2012: David Ebb; William Shay Ferguson; Allen M Goorin; Richard Gorlick; Holcombe Grier; Mark Krailo; G Douglas Letson; Steven E Lipshultz; Karen Marcus; Donald A Barkauskas; Peter Beardsley; Mark Bernstein; Meenakshi Devidas; Paul Meyers; Gene P Siegal; Neyssa Marina
Phase II trial of trastuzumab in combination with cytotoxic chemotherapy for treatment of metastatic osteosarcoma with human epidermal growth factor receptor 2 overexpression: a report from the children's oncology group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2012;30(20):2545-51.
2012: Kenneth H Kim; Janis P O'Malley; Meredith A Preuss; Souheil Saddekni; Gene P Siegal; Minghui Wang; Zhiying You; Kurt R Zinn; Rosemarie Aurigemma; David T Curiel; Igor Dmitriev; Raymond D Harris; Ronald D Alvarez
A phase I clinical trial of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in patients with recurrent gynecologic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(12):3440-51.
2012: Shuting Bai; Gene P Siegal; Nirag C Jhala
Foxp3 expression patterns in microscopic colitides: a clinicopathologic study of 69 patients.
American journal of clinical pathology 2012;137(6):931-6.
2012: Zenggang Pan; Warren G Sanger; Gene P Siegal; Julia A Bridge; William J Hunter; Shi Wei
A novel t(6;13)(q15;q34) translocation in a giant cell reparative granuloma (solid aneurysmal bone cyst).
Human pathology 2012;43(6):952-7.
2012: Margaret Brandwein-Gensler; Gene P Siegal
Striking pathology gold: a singular experience with daily reverberations: sinonasal hemangiopericytoma (glomangiopericytoma) and oncogenic osteomalacia.
Head and neck pathology 2012;6(1):64-74.
2012: Amberly L Nunez; Vishnu V B Reddy; Gene P Siegal; Shi Wei
CD138 (syndecan-1) expression in bone-forming tumors.
American journal of clinical pathology 2012;137(3):423-8.
2012: Yanqing Zhang; Yuan Zhang; Robert N Bone; WANXING CUI; Ji-Bin Peng; Gene P Siegal; Hongjun Wang; Hongju Wu
Regeneration of pancreatic non-β endocrine cells in adult mice following a single diabetes-inducing dose of streptozotocin.
PloS one 2012;7(5):e36675.
2011: Shi Wei; Gene P Siegal
A 23-year-old woman with a right femoral neck fracture.
JAMA : the journal of the American Medical Association 2011;306(21):2385-6.
2011: Jing Cheng; Xu Feng; Jianzhong Liu; Shaokai Luo; Zhenqi Shi; Gene P Siegal; Duorong Xu; Shi Wei
Interleukin-4 inhibits RANKL-induced NFATc1 expression via STAT6: a novel mechanism mediating its blockade of osteoclastogenesis.
Journal of cellular biochemistry 2011;112(11):3385-92.
2011: Jay J Listinsky; Gene P Siegal; Catherine M Listinsky
The emerging importance of α-L-fucose in human breast cancer: a review.
American journal of translational research 2011;3(4):292-322.
2011: Chuanyu Li; Gene P Siegal; Eric C Toline; Xiangmin Zhao; Renee A Desmond; Lynda M Evans; Arig Ibrahim-Hashim; Robert W Hardy
Prevention of carcinogenesis and inhibition of breast cancer tumor burden by dietary stearate.
Carcinogenesis 2011;32(8):1251-8.
2011: Shuting Bai; Dezhi Wang; Michael J Klein; Gene P Siegal
Characterization of CXCR4 expression in chondrosarcoma of bone.
Archives of pathology & laboratory medicine 2011;135(6):753-8.
2011: John T Anderson; Meiqin Zeng; Qian Li; Ryan Stapley; Doyle Ray Moore; Balachandra Chenna; Naomi S Fineberg; Jaroslaw Zmijewski; Isam-Eldin Eltoum; Gene P Siegal; Amit Gaggar; Stephen Barnes; Sadanandan E Velu; Victor J Thannickal; Edward Abraham; Rakesh P Patel; Jack R Lancaster; David D Chaplin; Mark T Dransfield; Jessy S Deshane
Elevated levels of NO are localized to distal airways in asthma.
Free radical biology & medicine 2011;50(11):1679-88.
2011: P Darwin Bell; Wayne R Fitzgibbon; Kelli Sas; Antine E Stenbit; May Amria; Amber Houston; Ryan Reichert; Sandra Gilley; Gene P Siegal; John Bissler; Mehmet Bilgen; Peter Cheng-te Chou; Lisa M Guay-Woodford; Brad Yoder; Courtney J Haycraft; Brian Siroky
Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis.
Journal of the American Society of Nephrology : JASN 2011;22(5):839-48.
2011: Jonathan A Hensel; Diptiman Chanda; Sanjay Kumar; Anandi Sawant; William E Grizzle; Gene P Siegal; Selvarangan Ponnazhagan
LL-37 as a therapeutic target for late stage prostate cancer.
The Prostate 2011;71(6):659-70.
2011: Shi Wei; Yufeng Li; Gene P Siegal; Omar Hameed
Breast carcinomas with isolated bone metastases have different hormone receptor expression profiles than those with metastases to other sites or multiple organs.
Annals of diagnostic pathology 2011;15(2):79-83.
2011: Sherry W Yang; James J Cody; Angel A Rivera; Reinhard Waehler; Minghui Wang; Kristopher J Kimball; Ronald A Alvarez; Gene P Siegal; Joanne T Douglas; Selvarangan Ponnazhagan
Conditionally replicating adenovirus expressing TIMP2 for ovarian cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(3):538-49.
2011: Sherry W Yang; Angel A Rivera; Gene P Siegal; Reinhard Waehler; Diptiman Chanda; James J Cody; Joanne T Douglas; Selvarangan Ponnazhagan
Conditionally replicating adenovirus expressing TIMP2 increases survival in a mouse model of disseminated ovarian cancer.
PloS one 2011;6(10):e25131.
2011: Chandrakumar Shanmugam; Gene P Siegal; Bin Zhang; James A Posey; Harvey L Bumpers; Isam E Eltoum; William E Grizzle; Robert B Hines; Nirag C Jhala; Venkat R Katkoori; Upender Manne
Evaluation of lymph node numbers for adequate staging of Stage II and III colon cancer.
Journal of hematology & oncology 2011;4():25.
2010: Kristopher J Kimball; Meredith A Preuss; Mack N Barnes; Minghui Wang; Gene P Siegal; Wen Wan; Huichien Kuo; Souheil Saddekni; Cecil R Stockard; William E Grizzle; Raymond D Harris; Rosemarie Aurigemma; David T Curiel; Ronald D Alvarez
A phase I study of a tropism-modified conditionally replicative adenovirus for recurrent malignant gynecologic diseases.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(21):5277-87.
2010: Shi Wei; Michael G Conner; Kui Zhang; Gene P Siegal; Lea Novak
Juxtatumoral stromal reactions in uterine endometrioid adenocarcinoma and their prognostic significance.
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists 2010;29(6):562-7.
2010: Aleodor Andea; Raj Patel; Selvarangan Ponnazhagan; Sanjay Kumar; Patricia DeVilliers; Darshana Jhala; Isam Eltoum; Gene P Siegal
Merkel cell carcinoma: correlation of KIT expression with survival and evaluation of KIT gene mutational status.
Human pathology 2010;41(10):1405-12.
2010: Allyson C Baker; Luminita Rezeanu; Michael J Klein; Michael J Pitt; Peter Buecker; Joseph H Hersh; John J Buchino; Gene P Siegal
Aggressive osteoblastoma: a case report involving a unique chromosomal aberration.
International journal of surgical pathology 2010;18(3):219-24.
2010: Joanne T Douglas; Angel A Rivera; Gray R Lyons; Patricia F Lott; Dezhi Wang; Majd zayzafoon; Gene P Siegal; Xu Cao; Steven M Theiss
Ex vivo transfer of the Hoxc-8-interacting domain of Smad1 by a tropism-modified adenoviral vector results in efficient bone formation in a rabbit model of spinal fusion.
Journal of spinal disorders & techniques 2010;23(1):63-73.
2010: Catherine M Ketcham; Robert W Hardy; Brian Rubin; Gene P Siegal
What editors want in an abstract.
Laboratory investigation; a journal of technical methods and pathology 2010;90(1):4-5.
2010: Shaoying Li; Gene P Siegal
Small cell tumors of bone.
Advances in anatomic pathology 2010;17(1):1-11.
2009: Holly Burford; Zubair Baloch; Xiuli Liu; Darshana Jhala; Gene P Siegal; Nirag C Jhala
E-cadherin/beta-catenin and CD10: a limited immunohistochemical panel to distinguish pancreatic endocrine neoplasm from solid pseudopapillary neoplasm of the pancreas on endoscopic ultrasound-guided fine-needle aspirates of the pancreas.
American journal of clinical pathology 2009;132(6):831-9.
2009: Diptiman Chanda; Tatyana Isayeva; Sanjay Kumar; Jonathan A Hensel; Anandi Sawant; Girish Ramaswamy; Gene P Siegal; Matthew S Beatty; Selvarangan Ponnazhagan
Therapeutic potential of adult bone marrow-derived mesenchymal stem cells in prostate cancer bone metastasis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(23):7175-85.
2009: Kristopher J Kimball; Angel A Rivera; Kurt R Zinn; Mert Icyuz; Vaibhav Saini; Jing Li; Zeng B Zhu; Gene P Siegal; Joanne T Douglas; David T Curiel; Ronald D Alvarez; Anton V Borovjagin
Novel infectivity-enhanced oncolytic adenovirus with a capsid-incorporated dual-imaging moiety for monitoring virotherapy in ovarian cancer.
Molecular imaging 2009;8(5):264-77.
2009: Kellie Matthews; Patricia E Noker; Baohong Tian; Sheila D Grimes; Ronna Fulton; Karen Schweikart; Raymond Harris; Rose Aurigemma; Minghui Wang; Mack N Barnes; Gene P Siegal; Akseli Hemminki; Kurt Zinn; David T Curiel; Ronald D Alvarez
Identifying the safety profile of Ad5.SSTR/TK.RGD, a novel infectivity-enhanced bicistronic adenovirus, in anticipation of a phase I clinical trial in patients with recurrent ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):4131-7.
2009: Alexander Stoff; Angel A Rivera; N Sanjib Banerjee; Steven T Moore; T Michael Numnum; Antonio Espinosa-de-los-Monteros; Dirk F Richter; Gene P Siegal; Louise T Chow; Dale Feldman; Luis O Vasconez; J Michael Mathis; Mariam A Stoff-Khalili; David T Curiel
Promotion of incisional wound repair by human mesenchymal stem cell transplantation.
Experimental dermatology 2009;18(4):362-9.
2009: Mert Icyuz; Stacie M J Bryant; Henry K Fortinberry; Kfir Molakandov; Gene P Siegal; Juan L Contreras; Hongju Wu
Adenovirus infection activates akt1 and induces cell proliferation in pancreatic islets1.
Transplantation 2009;87(6):821-4.
2009: Gene P Siegal
Navigating interpersonal conflict and peer review.
Laboratory investigation; a journal of technical methods and pathology 2009;89(3):256-8.
2009: Lynda M Evans; Stephanie L Cowey; Gene P Siegal; Robert W Hardy
Stearate preferentially induces apoptosis in human breast cancer cells.
Nutrition and cancer 2009;61(5):746-53.
2009: Herrick J Siegel; Ouida Brown; Robert Lopez-Ben; Gene P Siegal
Unplanned surgical excision of extremity soft tissue sarcomas: patient profile and referral patterns.
Journal of surgical orthopaedic advances 2009;18(2):93-8.
2009: Lynda M Evans; Eric C Toline; Renee Desmond; Gene P Siegal; Arig Ibrahim Hashim; Robert W Hardy
Dietary stearate reduces human breast cancer metastasis burden in athymic nude mice.
Clinical & experimental metastasis 2009;26(5):415-24.
2009: Gene P Siegal
Who's on first?
Laboratory investigation; a journal of technical methods and pathology 2009;89(1):4-5.
2008: Yan Y Sanders; Annie Pardo; Moisés Selman; Gerard J Nuovo; Trygve O Tollefsbol; Gene P Siegal; James Hagood
Thy-1 promoter hypermethylation: a novel epigenetic pathogenic mechanism in pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2008;39(5):610-8.
2008: Jennifer S Guimbellot; James A Fortenberry; Gene P Siegal; Bryan Moore; Hui Wen; Charles Venglarik; Yiu-Fai Chen; Suzanne Oparil; Eric J Sorscher; Jeong S Hong
Role of oxygen availability in CFTR expression and function.
American journal of respiratory cell and molecular biology 2008;39(5):514-21.
2008: Jeffrey D Goldsmith; Gene P Siegal; Saul Suster; Thomas M Wheeler; Richard W Brown
Reporting guidelines for clinical laboratory reports in surgical pathology.
Archives of pathology & laboratory medicine 2008;132(10):1608-16.
2008: Nirag C Jhala; Gene P Siegal; Darshana Jhala
Large, clear cytoplasmic vacuolation: an under-recognized cytologic clue to distinguish solid pseudopapillary neoplasms of the pancreas from pancreatic endocrine neoplasms on fine-needle aspiration.
Cancer 2008;114(4):249-54.
2008: Lakisha D Moore; Tatyana Isayeva; Gene P Siegal; Selvarangan Ponnazhagan
Silencing of transforming growth factor-beta1 in situ by RNA interference for breast cancer: implications for proliferation and migration in vitro and metastasis in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4961-70.
2008: Jaroslaw W Zmijewski; Emmanuel Lorne; Xia Zhao; Yuko Tsuruta; Yonggang Sha; Gang Liu; Gene P Siegal; Edward Abraham
Mitochondrial respiratory complex I regulates neutrophil activation and severity of lung injury.
American journal of respiratory and critical care medicine 2008;178(2):168-79.
2008: D Wang; Cecil R Stockard; Lualhati Harkins; P Lott; C Salih; K Yuan; D Buchsbaum; A Hashim; Majd zayzafoon; R W Hardy; O Hameed; William E Grizzle; Gene P Siegal
Immunohistochemistry in the evaluation of neovascularization in tumor xenografts.
Biotechnic & histochemistry : official publication of the Biological Stain Commission 2008;83(3):179-89.
2008: Kun Yuan; Catherine M Listinsky; Raj K Singh; Jay J Listinsky; Gene P Siegal
Cell surface associated alpha-L-fucose moieties modulate human breast cancer neoplastic progression.
Pathology oncology research : POR 2008;14(2):145-56.
2008: Yuko Tsuruta; Larisa Pereboeva; Martina Breidenbach; Daniel T Rein; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Paul Dent; Paul B Fisher; David T Curiel
A fiber-modified mesothelin promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(11):3582-8.
2008: Zeng B Zhu; Baogen Lu; Miey Park; Sharmila K Makhija; Thomas M Numnum; James E Kendrick; Minghui Wang; Yuko Tsuruta; Paul Fisher; Ronald D Alvarez; Fen Zhou; Gene P Siegal; Hongju Wu; David T Curiel
Development of an optimized conditionally replicative adenoviral agent for ovarian cancer.
International journal of oncology 2008;32(6):1179-88.
2008: Darshana Jhala; Susan Coventry; Pullivarthi Rao; Frank Yen; Gene P Siegal
Juvenile juxtacortical chondromyxoid fibroma of bone: a case report.
Human pathology 2008;39(6):960-5.
2008: C P L Paul; Maaike Everts; Joel N Glasgow; Paul Dent; Paul B Fisher; Ilya V Ulasov; Maciej S. Lesniak; Mariam A Stoff-Khalili; Justin Roth; M A Preuss; C M F Dirven; M L M Lamfers; Gene P Siegal; Zeng B Zhu; David T Curiel
Characterization of infectivity of knob-modified adenoviral vectors in glioma.
Cancer biology & therapy 2008;7(5):786-93.
2008: Diptiman Chanda; Tatyana Isayeva; Sanjay Kumar; Gene P Siegal; April A Szafran; Kurt R Zinn; Vishnu V B Reddy; Selvarangan Ponnazhagan
Systemic osteoprotegerin gene therapy restores tumor-induced bone loss in a therapeutic model of breast cancer bone metastasis.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(5):871-8.
2008: Herrick J Siegel; William H Dunahm; Robert Lopez-Ben; Gene P Siegal
Intracranial metastasis from synovial sarcoma.
Orthopedics 2008;31(4):405.
2008: Kun Yuan; Dennis Kucik; Raj K Singh; Catherine M Listinsky; Jay J Listinsky; Gene P Siegal
Alterations in human breast cancer adhesion-motility in response to changes in cell surface glycoproteins displaying alpha-L-fucose moieties.
International journal of oncology 2008;32(4):797-807.
2008: Chandrakumar Shanmugam; Venkat R Katkoori; Nirag C Jhala; William E Grizzle; Gene P Siegal; Upender Manne
p53 Nuclear accumulation and Bcl-2 expression in contiguous adenomatous components of colorectal adenocarcinomas predict aggressive tumor behavior.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2008;56(3):305-12.
2008: Mariam A Stoff-Khalili; Angel A Rivera; Ana Nedeljkovic-Kurepa; Arrigo DeBenedetti; Xiao-Lin Li; Yoshinobu Odaka; Jagat Podduturi; Don Arthur Sibley; Gene P Siegal; Alexander Stoff; Scott Young; Zeng B Zhu; David T Curiel; J Michael Mathis
Cancer-specific targeting of a conditionally replicative adenovirus using mRNA translational control.
Breast cancer research and treatment 2008;108(1):43-55.
2008: Paul A Meyers; Cindy L Schwartz; Mark Krailo; John Healey; Mark L Bernstein; Donna Betcher; William Shay Ferguson; Mark C Gebhardt; Allen M Goorin; Michael B Harris; Eugenie S Kleinerman; Michael P Link; Helen Nadel; Michael Nieder; Gene P Siegal; Michael A Weiner; Robert J Wells; Richard B Womer; Holcombe E Grier
Osteosarcoma: the addition of muramyl tripeptide to chemotherapy improves overall survival--a report from the Children's Oncology Group.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(4):633-8.
2008: Shi Wei; Gene P Siegal
Mechanisms modulating inflammatory osteolysis: a review with insights into therapeutic targets.
Pathology, research and practice 2008;204(10):695-706.
2008: Amy L Adams; Gene P Siegal; Nirag C Jhala
Solid pseudopapillary tumor of the pancreas: a review of salient clinical and pathologic features.
Advances in anatomic pathology 2008;15(1):39-45.
2007: Yuko Tsuruta; Young-Jun Park; Gene P Siegal; Gang Liu; Edward Abraham
Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(10):7079-86.
2007: Allyson C Baker; Luminita Rezeanu; Sabine O'Laughlin; Krishnan Unni; Michael J Klein; Gene P Siegal
Juxtacortical chondromyxoid fibroma of bone: a unique variant: a case study of 20 patients.
The American journal of surgical pathology 2007;31(11):1662-8.
2007: Zeng B Zhu; J Michael Mathis; Sharmila K Makhija; Baogen Lu; Minghui Wang; Shaonin Ji; Angel A Rivera; Eben Rosenthal; Gene P Siegal; David T Curiel
Targeting of a conditionally replicative adenovirus agent to human squamous cell carcinomas of the head and neck.
International journal of oncology 2007;31(5):1213-22.
2007: Mariam A Stoff-Khalili; Angel A Rivera; J Michael Mathis; nirupama banerjee; Amanda S Moon; A Hess; Rodney P Rocconi; T Michael Numnum; Maaike Everts; Louise T Chow; Joanne T Douglas; Gene P Siegal; Zeng B Zhu; Hans Georg Bender; Peter Dall; Alexander Stoff; Larisa Pereboeva; David T Curiel
Mesenchymal stem cells as a vehicle for targeted delivery of CRAds to lung metastases of breast carcinoma.
Breast cancer research and treatment 2007;105(2):157-67.
2007: Kaiyu Yuan; Leland W K Chung; Gene P Siegal; Majd zayzafoon
alpha-CaMKII controls the growth of human osteosarcoma by regulating cell cycle progression.
Laboratory investigation; a journal of technical methods and pathology 2007;87(9):938-50.
2007: Herrick J Siegel; Robert Lopez-Ben; Nasser Said-Al-Naief; Gene P Siegal
An 18-year-old Man with Knee Pain.
Clinical orthopaedics and related research 2007;462():242-7.
2007: Yuko Tsuruta; Larisa Pereboeva; Joel N Glasgow; Daniel T Rein; Yosuke Kawakami; Ronald D Alvarez; Rodney P Rocconi; Gene P Siegal; Paul Dent; Paul B Fisher; David T Curiel
A mosaic fiber adenovirus serotype 5 vector containing reovirus sigma 1 and adenovirus serotype 3 knob fibers increases transduction in an ovarian cancer ex vivo system via a coxsackie and adenovirus receptor-independent pathway.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(9):2777-83.
2007: Alexander Stoff; Angel A Rivera; J Michael Mathis; Steven T Moore; nirupama banerjee; Maaike Everts; Antonio Espinosa-de-los-Monteros; Zdenek Novak; Luis O Vasconez; Thomas R Broker; Dirk F Richter; Dale Feldman; Gene P Siegal; Mariam A Stoff-Khalili; David T Curiel
Effect of adenoviral mediated overexpression of fibromodulin on human dermal fibroblasts and scar formation in full-thickness incisional wounds.
Journal of molecular medicine (Berlin, Germany) 2007;85(5):481-96.
2007: John T Lam; Akseli Hemminki; Anna Kanerva; K B Lee; Jerry L Blackwell; Renee A Desmond; Gene P Siegal; David T Curiel
A three-dimensional assay for measurement of viral-induced oncolysis.
Cancer gene therapy 2007;14(4):421-30.
2007: M Adhiambo Witlox; Martine L M Lamfers; Paul I J M Wuisman; David T Curiel; Gene P Siegal
Evolving gene therapy approaches for osteosarcoma using viral vectors: review.
Bone 2007;40(4):797-812.
2007: Jessy Deshane; Sifeng Chen; Sergio Caballero; Anna Grochot-Przeczek; Halina Was; Sergio Li Calzi; Radoslaw Lach; Thomas Hock; Bo Chen; Nathalie Hill-Kapturczak; Gene P Siegal; Jozef Dulak; Alicja Jozkowicz; Maria B Grant; Anupam Agarwal
Stromal cell-derived factor 1 promotes angiogenesis via a heme oxygenase 1-dependent mechanism.
The Journal of experimental medicine 2007;204(3):605-18.
2007: Mariam A Stoff-Khalili; Angel A Rivera; Alexander Stoff; J Michael Mathis; Rodney P Rocconi; Qiana L Matthews; Michael T Numnum; Isabell Herrmann; Peter Dall; Devin E Eckhoff; Joanne T Douglas; Gene P Siegal; Zeng B Zhu; David T Curiel
Combining high selectivity of replication via CXCR4 promoter with fiber chimerism for effective adenoviral oncolysis in breast cancer.
International journal of cancer. Journal international du cancer 2007;120(4):935-41.
2007: Zeng B Zhu; Angel A Rivera; Sharmila K Makhija; Baogen Lu; Minghui Wang; Miiru Izumi; Robert James Cerfolio; Mariam A Stoff-Khalili; Fen Zhou; Koichi Takayama; Gene P Siegal; David T Curiel
Targeting lung cancer using an infectivity enhanced CXCR4-CRAd.
Lung cancer (Amsterdam, Netherlands) 2007;55(2):145-56.
2007: Tie Han; Yizhe Tang; Hideyo Ugai; Leslie E Perry; Gene P Siegal; Juan L Contreras; Hongju Wu
Genetic incorporation of the protein transduction domain of Tat into Ad5 fiber enhances gene transfer efficacy.
Virology journal 2007;4():103.
2007: Shi Wei; Gene P Siegal
p38 MAPK as a potential therapeutic target for inflammatory osteolysis.
Advances in anatomic pathology 2007;14(1):42-5.
2007: David C Chhieng; Gene P Siegal
Wandering chordoma--a mid-line crisis?
Skeletal radiology 2007;36(1):1-3.
2006: Bruce F Smith; David T Curiel; Vladimir V Ternovoi; Anton V Borovjagin; Henry J Baker; Nancy Cox; Gene P Siegal
Administration of a conditionally replicative oncolytic canine adenovirus in normal dogs.
Cancer biotherapy & radiopharmaceuticals 2006;21(6):601-6.
2006: Xiuli Liu; Tracy M Rauch; Gene P Siegal; Nirag C Jhala
Solid-pseudopapillary neoplasm of the pancreas: Three cases with a literature review.
Applied immunohistochemistry & molecular morphology : AIMM / official publication of the Society for Applied Immunohistochemistry 2006;14(4):445-53.
2006: walter bell; M J Klein; Michael J Pitt; Gene P Siegal
Molecular pathology of chondroid neoplasms: part 2, malignant lesions.
Skeletal radiology 2006;35(12):887-94.
2006: walter bell; M J Klein; Michael J Pitt; Gene P Siegal
Molecular pathology of chondroid neoplasms: part 1, benign lesions.
Skeletal radiology 2006;35(11):805-13.
2006: Zeng B Zhu; Yabing Chen; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Masato Yamamoto; shuyi wang; Gene P Siegal; David T Curiel; Jay M McDonald
Survivin promoter-based conditionally replicative adenoviruses target cholangiocarcinoma.
International journal of oncology 2006;29(5):1319-29.
2006: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; shuyi wang; Koichi Takayama; Gene P Siegal; Paul N Reynolds; David T Curiel
Targeting mesothelioma using an infectivity enhanced survivin-conditionally replicative adenoviruses.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2006;1(7):701-11.
2006: Xiuli Liu; Audrey J Lazenby; Gene P Siegal
Signal transduction cross-talk during colorectal tumorigenesis.
Advances in anatomic pathology 2006;13(5):270-4.
2006: Vladimir V Ternovoi; David T Curiel; Bruce F Smith; Gene P Siegal
Adenovirus-mediated p53 tumor suppressor gene therapy of osteosarcoma.
Laboratory investigation; a journal of technical methods and pathology 2006;86(8):748-66.
2006: Mariam A Stoff-Khalili; Angel A Rivera; Long P Le; Alexander Stoff; Maaike Everts; Juan L Contreras; D Chen; L Teng; Marianne G Rots; Hidde J Haisma; Rodney P Rocconi; Gerd J Bauerschmitz; Daniel T Rein; Masato Yamamoto; Gene P Siegal; Peter Dall; J Michael Mathis; David T Curiel
Employment of liver tissue slice analysis to assay hepatotoxicity linked to replicative and nonreplicative adenoviral agents.
Cancer gene therapy 2006;13(6):606-18.
2006: Michael J Klein; Gene P Siegal
Osteosarcoma: anatomic and histologic variants.
American journal of clinical pathology 2006;125(4):555-81.
2006: Winan J van Houdt; Yosef S Haviv; Baogen Lu; Minghui Wang; Angel A Rivera; Ilya V Ulasov; Martine L M Lamfers; Daniel T Rein; Lesniak Maciej; Gene P Siegal; Clemens M F Dirven; David T Curiel; Zeng B Zhu
The human survivin promoter: a novel transcriptional targeting strategy for treatment of glioma.
Journal of neurosurgery 2006;104(4):583-92.
2006: Long P Le; Angel A Rivera; Joel N Glasgow; Vladimir V Ternovoi; Hongju Wu; Minghui Wang; Bruce F Smith; Gene P Siegal; David T Curiel
Infectivity enhancement for adenoviral transduction of canine osteosarcoma cells.
Gene therapy 2006;13(5):389-99.
2006: Nasser Said-Al-Naief; Rui Fernandes; Patrick Louis; Walter Bell; Gene P Siegal
Desmoplastic fibroma of the jaw: a case report and review of literature.
Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics 2006;101(1):82-94.
2005: Long P Le; Jing Li; Vladimir V Ternovoi; Gene P Siegal; David T Curiel
Fluorescently tagged canine adenovirus via modification with protein IX-enhanced green fluorescent protein.
The Journal of general virology 2005;86(Pt 12):3201-8.
2005: Michael J Passineau; Gene P Siegal; Maaike Everts; Alexander Pereboev; Darshana Jhala; Minghui Wang; Zeng B Zhu; Sangae Kim Park; David T Curiel; Gina M Nelson
The natural history of a novel, systemic, disseminated model of syngeneic mouse B-cell lymphoma.
Leukemia & lymphoma 2005;46(11):1627-1638.
2005: Isam A Eltoum; Mohamad A Eloubeidi; David C Chhieng; Ashutosh Tamhane; Ralph Crowe; Darshana Jhala; Kay D St John; C Mel Wilcox; Gene P Siegal; Selwyn Vickers; Nirag C Jhala
Cytologic grade independently predicts survival of patients with pancreatic adenocarcinoma.
American journal of clinical pathology 2005;124(5):697-707.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; J Michael Mathis; Maaike Everts; Minghui Wang; Yosuke Kawakami; Reinhard Waehler; Quiana L Mathews; Masato Yamamoto; Rodney P Rocconi; Gene P Siegal; Dirk F Richter; Peter Dall; Zeng B Zhu; David T Curiel
Gene transfer to carcinoma of the breast with fiber-modified adenoviral vectors in a tissue slice model system.
Cancer biology & therapy 2005;4(11):1203-10.
2005: James Hagood; Priya Prabhakaran; Pallavi Kumbla; Lorena Salazar; Mark W MacEwen; Thomas Barker; Luis A Ortiz; Trenton R Schoeb; Gene P Siegal; C Bruce Alexander; Annie Pardo; Moisés Selman
Loss of fibroblast Thy-1 expression correlates with lung fibrogenesis.
The American journal of pathology 2005;167(2):365-79.
2005: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; SangAe Kim-Park; Ilya V Ulasov; Fen Zhou; Ronald D Alvarez; Gene P Siegal; David T Curiel
Incorporating the survivin promoter in an infectivity enhanced CRAd-analysis of oncolysis and anti-tumor effects in vitro and in vivo.
International journal of oncology 2005;27(1):237-46.
2005: Daniel T Rein; Martina Breidenbach; Tyler O Kirby; Tie Han; Gene P Siegal; Gerd J Bauerschmitz; Minghui Wang; Dirk M Nettelbeck; Yuko Tsuruta; Masato Yamamoto; Peter Dall; Akseli Hemminki; David T Curiel
A fiber-modified, secretory leukoprotease inhibitor promoter-based conditionally replicating adenovirus for treatment of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(3):1327-35.
2005: G Steven Bova; Isam A Eltoum; John A Kiernan; Gene P Siegal; Andra R Frost; Carolyn J M Best; John W Gillespie; Gloria H Su; Michael R Emmert-Buck
Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications.
Molecular biotechnology 2005;29(2):119-52.
2005: Minghui Wang; Akseli Hemminki; Gene P Siegal; Mack N Barnes; Igor Dmitriev; Victor Krasnykh; Bin Liu; David T Curiel; Ronald D Alvarez
Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery.
Gynecologic oncology 2005;96(2):341-8.
2005: Mariam A Stoff-Khalili; Alexander Stoff; Angel A Rivera; nirupama banerjee; Maaike Everts; Scott Young; Gene P Siegal; Dirk F Richter; Minghui Wang; Peter Dall; J Michael Mathis; Zeng B Zhu; David T Curiel
Preclinical evaluation of transcriptional targeting strategies for carcinoma of the breast in a tissue slice model system.
Breast cancer research : BCR 2005;7(6):R1141-52.
2005: Vladimir V Ternovoi; Long P Le; Natalya Belousova; Bruce F Smith; Gene P Siegal; David T Curiel
Productive replication of human adenovirus type 5 in canine cells.
Journal of virology 2005;79(2):1308-11.
2005: G Steven Bova; Isam A Eltoum; John A Kiernan; Gene P Siegal; Andra R Frost; Carolyn J M Best; John W Gillespie; Michael R Emmert-Buck
Optimal molecular profiling of tissue and tissue components: defining the best processing and microdissection methods for biomedical applications.
Methods in molecular medicine 2005;103():15-66.
2005: Gandham Mahendra; Sanjay Kumar; Tatyana Isayeva; Parameshwar J Mahasreshti; David T Curiel; Cecil R Stockardt; William E Grizzle; Vidya Alapati; Raj K Singh; Gene P Siegal; Sreelatha Meleth; Selvarangan Ponnazhagan
Antiangiogenic cancer gene therapy by adeno-associated virus 2-mediated stable expression of the soluble FMS-like tyrosine kinase-1 receptor.
Cancer gene therapy 2005;12(1):26-34.
2004: John T Lam; Anna Kanerva; Gerd J Bauerschmitz; Koichi Takayama; Kaori Suzuki; Masato Yamamoto; Snehal M Bhoola; Bin Liu; Minghui Wang; Mack N Barnes; Ronald D Alvarez; Gene P Siegal; David T Curiel; Akseli Hemminki
Inter-patient variation in efficacy of five oncolytic adenovirus candidates for ovarian cancer therapy.
The journal of gene medicine 2004;6(12):1333-42.
2004: Daniel T Rein; Martina Breidenbach; Dirk M Nettelbeck; Yosuke Kawakami; Gene P Siegal; Warner K Huh; Minghui Wang; Akseli Hemminki; Gerd J Bauerschmitz; Masato Yamamoto; Yasuo Adachi; Koichi Takayama; Peter Dall; David T Curiel
Evaluation of tissue-specific promoters in carcinomas of the cervix uteri.
The journal of gene medicine 2004;6(11):1281-9.
2004: Julie E Adams; Robert Lopez-Ben; Richard D Meyer; Gene P Siegal
A 32-year-old man with knee pain.
Clinical orthopaedics and related research 2004;(427):272-7.
2004: Fadi W Abdul-Karim; Thomas W Bauer; Scott E Kilpatrick; Kevin A Raymond; Gene P Siegal
Recommendations for the reporting of bone tumors. Association of Directors of Anatomic and Surgical Pathology.
Human pathology 2004;35(10):1173-8.
2004: Zeng B Zhu; Sharmila K Makhija; Baogen Lu; Minghui Wang; Angel A Rivera; Meredith Preuss; Fen Zhou; Gene P Siegal; Ronald D Alvarez; David T Curiel
Transport across a polarized monolayer of Caco-2 cells by transferrin receptor-mediated adenovirus transcytosis.
Virology 2004;325(1):116-28.
2004: Eric W Price; Robert Lopez; Kenneth A Jaffe; Gene P Siegal; Katrin Klemm
Ulnar mass in a 51-year-old woman.
Clinical orthopaedics and related research 2004;(424):272-9.
2004: Joel N Glasgow; Eric J Kremer; Akseli Hemminki; Gene P Siegal; Joanne T Douglas; David T Curiel
An adenovirus vector with a chimeric fiber derived from canine adenovirus type 2 displays novel tropism.
Virology 2004;324(1):103-16.
2004: Julie Elizabeth Adams; Robert Lopez-Ben; Kenneth A Jaffe; Gene P Siegal
A 36-year-old woman with a toe mass.
Clinical orthopaedics and related research 2004;(421):314-21.
2004: Anna Kanerva; Gerd J Bauerschmitz; Masato Yamamoto; John T Lam; Ronald D Alvarez; Gene P Siegal; David T Curiel; Akseli Hemminki
A cyclooxygenase-2 promoter-based conditionally replicating adenovirus with enhanced infectivity for treatment of ovarian adenocarcinoma.
Gene therapy 2004;11(6):552-9.
2003: David C Chhieng; Elizabeth Benson; Isam Eltoum; Mohamad A Eloubeidi; Nirag C Jhala; Darshana Jhala; Gene P Siegal; William E Grizzle; Upender Manne
MUC1 and MUC2 expression in pancreatic ductal carcinoma obtained by fine-needle aspiration.
Cancer 2003;99(6):365-71.
2003: Darshana Jhala; Isam Eltoum; Andrew J Carroll; Robert Lopez-Ben; Dolores Lopez-Terrada; Pulivarthi H Rao; Mark J Pettenati; Gene P Siegal
Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud's syndrome: a case report emphasizing the cytological and cytogenetic findings.
Human pathology 2003;34(12):1354-7.
2003: Masato Yamamoto; Julia Davydova; Minghui Wang; Gene P Siegal; Victor Krasnykh; Selwyn M Vickers; David T Curiel
Infectivity enhanced, cyclooxygenase-2 promoter-based conditionally replicative adenovirus for pancreatic cancer.
Gastroenterology 2003;125(4):1203-18.
2003: Hejal C Patel; Robert Lopez-Ben; Kenneth A Jaffe; Gene P Siegal
Painful sclerotic medial clavicle in a 46-year-old woman.
Clinical orthopaedics and related research 2003;(414):342-6.
2003: Parameshwar J Mahasreshti; Manjula Kataram; Ming H Wang; Cecil R Stockard; William E Grizzle; Delicia Carey; Gene P Siegal; Hidde J Haisma; Ronald D Alvarez; David T Curiel
Intravenous delivery of adenovirus-mediated soluble FLT-1 results in liver toxicity.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2701-10.
2003: John T Lam; Gerd J Bauerschmitz; Anna Kanerva; Shannon D Barker; J Michael Straughn; Minghui Wang; Mack N Barnes; Jerry L Blackwell; Gene P Siegal; Ronald D Alvarez; David T Curiel; Akseli Hemminki
Replication of an integrin targeted conditionally replicating adenovirus on primary ovarian cancer spheroids.
Cancer gene therapy 2003;10(5):377-87.
2003: Akseli Hemminki; Anna Kanerva; Bin Liu; Minghui Wang; Ronald D Alvarez; Gene P Siegal; David T Curiel
Modulation of coxsackie-adenovirus receptor expression for increased adenoviral transgene expression.
Cancer research 2003;63(4):847-53.
2003: Julie Elizabeth Adams; Kenneth A Jaffe; Jack E Lemons; Gene P Siegal
Prosthetic implant associated sarcomas: a case report emphasizing surface evaluation and spectroscopic trace metal analysis.
Annals of diagnostic pathology 2003;7(1):35-46.
2003: Akseli Hemminki; Anna Kanerva; Eric J Kremer; Gerd J Bauerschmitz; Bruce F Smith; Bin Liu; Minghui Wang; Renee A Desmond; Anne Keriel; Brian G Barnett; Henry J Baker; Gene P Siegal; David T Curiel
A canine conditionally replicating adenovirus for evaluating oncolytic virotherapy in a syngeneic animal model.
Molecular therapy : the journal of the American Society of Gene Therapy 2003;7(2):163-73.
2003: Nirag C Jhala; Gene P Siegal; Katrin Klemm; Barbara F Atkinson; Darshana Jhala
Infiltration of Helicobacter pylori in the gastric mucosa.
American journal of clinical pathology 2003;119(1):101-7.
2002: Matthew V Sheffield; Herman Yee; Christine C Dorvault; Katherine N Weilbaecher; Isam A Eltoum; Gene P Siegal; David E Fisher; David C Chhieng
Comparison of five antibodies as markers in the diagnosis of melanoma in cytologic preparations.
American journal of clinical pathology 2002;118(6):930-6.
2002: Isam A Eltoum; Gene P Siegal; Andra R Frost
Microdissection of histologic sections: past, present, and future.
Advances in anatomic pathology 2002;9(5):316-22.
2002: Anna Kanerva; Minghui Wang; Gerd J Bauerschmitz; John T Lam; Renee A Desmond; Snehal M Bhoola; Mack N Barnes; Ronald D Alvarez; Gene P Siegal; David T Curiel; Akseli Hemminki
Gene transfer to ovarian cancer versus normal tissues with fiber-modified adenoviruses.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(6):695-704.
2002: Brian D Ragland; walter bell; Robert R Lopez; Gene P Siegal
Cytogenetics and molecular biology of osteosarcoma.
Laboratory investigation; a journal of technical methods and pathology 2002;82(4):365-73.
2002: Waleed O Arafat; Jesús Gómez-Navarro; Donald J Buchsbaum; Jialing Xiang; Minghui Wang; Enrique Casado; Shannon D Barker; Parameshwar J Mahasreshti; Hidde J Haisma; Mack N Barnes; Gene P Siegal; Ronald D Alvarez; Akseli Hemminki; Dirk M Nettelbeck; David T Curiel
Effective single chain antibody (scFv) concentrations in vivo via adenoviral vector mediated expression of secretory scFv.
Gene therapy 2002;9(4):256-62.
2002: Robert Lopez-Ben; Gene P Siegal; Mark N Hadley
Chondromyxoid fibroma of the cervical spine: case report.
Neurosurgery 2002;50(2):409-11.
2002: Allen M Goorin; Michael B Harris; Mark Bernstein; William Shay Ferguson; Meenakshi Devidas; Gene P Siegal; Mark C Gebhardt; Cindy L Schwartz; Michael Link; Holcombe E Grier
Phase II/III trial of etoposide and high-dose ifosfamide in newly diagnosed metastatic osteosarcoma: a pediatric oncology group trial.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2002;20(2):426-33.
2001: J J Listinsky; Catherine M Listinsky; V Alapati; Gene P Siegal
Cell surface fucose ablation as a therapeutic strategy for malignant neoplasms.
Advances in anatomic pathology 2001;8(6):330-7.
2001: Sate Hamza; P Anderson; Vishnu V B Reddy; Gene P Siegal
Use of the Internet in pathology resident training and education.
Advances in anatomic pathology 2001;8(5):290-7.
2001: J R Cusmariu; Robert Lopez-Ben; Gene P Siegal; Kenneth A Jaffe
Enlarging toe mass in a 13-year-old girl.
Clinical orthopaedics and related research 2001;(390):259-61, 264-9.
2001: Akseli Hemminki; Natalya Belousova; Kurt R Zinn; Bin Liu; Minghui Wang; Tandra R Chaudhuri; Buck E Rogers; Donald J Buchsbaum; Gene P Siegal; Mack N Barnes; Jesus Gomez-Navarro; David T Curiel; Ronald D Alvarez
An adenovirus with enhanced infectivity mediates molecular chemotherapy of ovarian cancer cells and allows imaging of gene expression.
Molecular therapy : the journal of the American Society of Gene Therapy 2001;4(3):223-31.
2001: Selvarangan Ponnazhagan; David T Curiel; Denise R Shaw; Ronald D Alvarez; Gene P Siegal
Adeno-associated virus for cancer gene therapy.
Cancer research 2001;61(17):6313-21.
2001: William Shay Ferguson; Michael B Harris; Allen M Goorin; Mark C Gebhardt; Michael P Link; S J Shochat; Gene P Siegal; Meenakshi Devidas; Holcombe E Grier
Presurgical window of carboplatin and surgery and multidrug chemotherapy for the treatment of newly diagnosed metastatic or unresectable osteosarcoma: Pediatric Oncology Group Trial.
Journal of pediatric hematology/oncology 2001;23(6):340-8.
2001: Enrique Casado; Dirk M Nettelbeck; Jesus Gomez-Navarro; Akseli Hemminki; Manuel Gonzalez Baron; Gene P Siegal; Mack N Barnes; Ronald D Alvarez; David T Curiel
Transcriptional targeting for ovarian cancer gene therapy.
Gynecologic oncology 2001;82(2):229-37.
2001: Enrique Casado; Jesus Gomez-Navarro; Masato Yamamoto; Yasuo Adachi; Candace J Coolidge; Waleed O Arafat; Shannon D Barker; Ming H Wang; Parameshwar J Mahasreshti; Akseli Hemminki; Manuel Gonzalez Baron; Mack N Barnes; TB Pustilnik; Gene P Siegal; Ronald D Alvarez; David T Curiel
Strategies to accomplish targeted expression of transgenes in ovarian cancer for molecular therapeutic applications.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(8):2496-504.
2001: Parameshwar J Mahasreshti; Jesus Gomez-Navarro; Manjula Kataram; Ming H Wang; Delicia Carey; Gene P Siegal; Mack N Barnes; Dirk M Nettelbeck; Ronald D Alvarez; Akseli Hemminki; David T Curiel
Adenovirus-mediated soluble FLT-1 gene therapy for ovarian carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2001;7(7):2057-66.
2001: Shannon D Barker; Enrique Casado; Jesus Gomez-Navarro; Jialing Xiang; Waleed O Arafat; Parameshwar J Mahasreshti; TB Pustilnik; Akseli Hemminki; Gene P Siegal; Ronald D Alvarez; David T Curiel
An immunomagnetic-based method for the purification of ovarian cancer cells from patient-derived ascites.
Gynecologic oncology 2001;82(1):57-63.
2001: P Cherry; Robert Lopez-Ben; Kenneth A Jaffe; Gene P Siegal
Paraspinal mass in a 14-year-old girl.
Clinical orthopaedics and related research 2001;(382):277-81, 283-4.
2000: Waleed O Arafat; Enrique Casado; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Joseph C Glorioso; David T Curiel; Jesús Gómez-Navarro
Genetically modified CD34+ cells exert a cytotoxic bystander effect on human endothelial and cancer cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(11):4442-8.
2000: Ronald D Alvarez; Jesus Gomez-Navarro; Minghui Wang; Mack N Barnes; Theresa V Strong; Ramin B Arani; Waleed O Arafat; J V Hughes; Gene P Siegal; David T Curiel
Adenoviral-mediated suicide gene therapy for ovarian cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;2(5):524-30.
2000: Waleed O Arafat; Jesús Gómez-Navarro; Jialing Xiang; Gene P Siegal; Ronald D Alvarez; David T Curiel
Antineoplastic effect of anti-erbB-2 intrabody is not correlated with scFv affinity for its target.
Cancer gene therapy 2000;7(9):1250-6.
2000: Ronald D Alvarez; Mack N Barnes; Jesus Gomez-Navarro; Minghui Wang; Theresa V Strong; Waleed O Arafat; Ramin B Arani; Martin R Johnson; B L Roberts; Gene P Siegal; David T Curiel
A cancer gene therapy approach utilizing an anti-erbB-2 single-chain antibody-encoding adenovirus (AD21): a phase I trial.
Clinical cancer research : an official journal of the American Association for Cancer Research 2000;6(8):3081-7.
2000: Thomas S Winokur; Stan McClellan; Gene P Siegal; David T Redden; P Gore; Audrey J Lazenby; V Reddy; Catherine M Listinsky; D A Conner; J Goldman; Gary J Grimes; Gregg Vaughn; J M McDonald
A prospective trial of telepathology for intraoperative consultation (frozen sections).
Human pathology 2000;31(7):781-5.
2000: Waleed O Arafat; Jesús Gómez-Navarro; Jialing Xiang; Mack N Barnes; Parameshwar J Mahasreshti; Ronald D Alvarez; Gene P Siegal; A O Badib; Donald J Buchsbaum; David T Curiel; Murray A Stackhouse
An adenovirus encoding proapoptotic Bax induces apoptosis and enhances the radiation effect in human ovarian cancer.
Molecular therapy : the journal of the American Society of Gene Therapy 2000;1(6):545-54.
2000: Jialing Xiang; Jesús Gómez-Navarro; Waleed O Arafat; Bin Liu; Shannon D Barker; Ronald D Alvarez; Gene P Siegal; David T Curiel
Pro-apoptotic treatment with an adenovirus encoding Bax enhances the effect of chemotherapy in ovarian cancer.
The journal of gene medicine 2000;2(2):97-106.
1999: Hanh M Khuu; D Moore; S Young; Kenneth A Jaffe; Gene P Siegal
Examination of tumor and tumor-like conditions of bone.
Annals of diagnostic pathology 1999;3(6):364-9.
1999: Isam A Eltoum; R J Moore; William Cook; D Ralph Crowe; W H Rodgers; Gene P Siegal
Epithelioid variant of malignant peripheral nerve sheath tumor (malignant schwannoma) of the urinary bladder.
Annals of diagnostic pathology 1999;3(5):304-8.
1999: Robert Lopez-Ben; Michael J Pitt; Kenneth A Jaffe; Gene P Siegal
Osteosarcoma in a patient with McCune-Albright syndrome and Mazabraud's syndrome.
Skeletal radiology 1999;28(9):522-6.
1999: T J Vanderkwaak; Minghui Wang; Jesús Gómez-Navarro; Claudine Rancourt; Igor Dmitriev; Victor Krasnykh; Mack Barnes; Gene P Siegal; R Alvarez; David T Curiel
An advanced generation of adenoviral vectors selectively enhances gene transfer for ovarian cancer gene therapy approaches.
Gynecologic oncology 1999;74(2):227-34.
1999: Kenneth A Jaffe; D H Pham; FS Chivers; Gene P Siegal
Pathologic femoral fracture in a 76-year-old woman.
Clinical orthopaedics and related research 1999;(364):276-80, 284-8.
1999: George Pan; Selwyn M Vickers; A Pickens; JO Phillips; W Ying; John A Thompson; Gene P Siegal; Jay M McDonald
Apoptosis and tumorigenesis in human cholangiocarcinoma cells. Involvement of Fas/APO-1 (CD95) and calmodulin.
The American journal of pathology 1999;155(1):193-203.
1999: Claudine Rancourt; Alain Piché; Jesus Gomez-Navarro; Minghui Wang; Ronald D Alvarez; Gene P Siegal; Gerald M Fuller; SA Jones; David T Curiel
Interleukin-6 modulated conditionally replicative adenovirus as an antitumor/cytotoxic agent for cancer therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(1):43-50.
1998: Minghui Wang; Claudine Rancourt; Jesus Gomez-Navarro; David M Krisky; Pierfrancesco Marconi; Thomas J Oligino; Ronald D Alvarez; Gene P Siegal; Joseph C Glorioso; David T Curiel
High-efficacy thymidine kinase gene transfer to ovarian cancer cell lines mediated by herpes simplex virus type 1 vector.
Gynecologic oncology 1998;71(2):278-87.
1998: J Averyt; FS Chivers; Kenneth A Jaffe; Gene P Siegal
Shoulder mass in a 38-year-old woman.
Clinical orthopaedics and related research 1998;(355):323-7, 330-2.
1998: Claudine Rancourt; Buck E Rogers; Barbara A Sosnowski; Minghui Wang; Alain Piché; Glenn F Pierce; Ronald D Alvarez; Gene P Siegal; Joanne T Douglas; David T Curiel
Basic fibroblast growth factor enhancement of adenovirus-mediated delivery of the herpes simplex virus thymidine kinase gene results in augmented therapeutic benefit in a murine model of ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(10):2455-61.
1998: J J Listinsky; Gene P Siegal; Catherine M Listinsky
Alpha-L-fucose: a potentially critical molecule in pathologic processes including neoplasia.
American journal of clinical pathology 1998;110(4):425-40.
1998: JE Grim; Gene P Siegal; Ronald D Alvarez; David T Curiel
Intracellular expression of the anti-erbB-2 sFv N29 fails to accomplish efficient target modulation.
Biochemical and biophysical research communications 1998;250(3):699-703.
1998: MW Robertson; Minghui Wang; Gene P Siegal; M Rosenfeld; R S Ashford; Ronald D Alvarez; Robert I Garver; David T Curiel
Use of a tissue-specific promoter for targeted expression of the herpes simplex virus thymidine kinase gene in cervical carcinoma cells.
Cancer gene therapy 1998;5(5):331-6.
1998: Thomas S Winokur; Stan McClellan; Gene P Siegal; V Reddy; Catherine M Listinsky; D Conner; J Goldman; Gary J Grimes; Gregg Vaughn; J M McDonald
An initial trial of a prototype telepathology system featuring static imaging with discrete control of the remote microscope.
American journal of clinical pathology 1998;110(1):43-9.
1998: MW Robertson; Mack N Barnes; Claudine Rancourt; Minghui Wang; JE Grim; Ronald D Alvarez; Gene P Siegal; David T Curiel
Gene therapy for ovarian carcinoma.
Seminars in oncology 1998;25(3):397-406.
1998: JE Grim; Jessy Deshane; Gene P Siegal; Ronald D Alvarez; P DiFiore; David T Curiel
The level of erbB2 expression predicts sensitivity to the cytotoxic effects of an intracellular anti-erbB2 sFv.
Journal of molecular medicine (Berlin, Germany) 1998;76(6):451-8.
1998: Feng Wang-Johanning; G Yancey Gillespie; JE Grim; Claudine Rancourt; Ronald D Alvarez; Gene P Siegal; David T Curiel
Intracellular expression of a single-chain antibody directed against human papillomavirus type 16 E7 oncoprotein achieves targeted antineoplastic effects.
Cancer research 1998;58(9):1893-900.
1998: Jesús Gómez-Navarro; Gene P Siegal; Ronald D Alvarez; David T Curiel
Gene therapy: ovarian carcinoma as the paradigm.
American journal of clinical pathology 1998;109(4):444-67.
1998: Claudine Rancourt; MW Robertson; Minghui Wang; CK Goldman; J F Kelly; Ronald D Alvarez; Gene P Siegal; David T Curiel
Endothelial cell vehicles for delivery of cytotoxic genes as a gene therapy approach for carcinoma of the ovary.
Clinical cancer research : an official journal of the American Association for Cancer Research 1998;4(2):265-70.
1997: C K Goldman; Buck E Rogers; Joanne T Douglas; Barbara A Sosnowski; W Ying; Gene P Siegal; Andrew Baird; J A Campain; David T Curiel
Targeted gene delivery to Kaposi's sarcoma cells via the fibroblast growth factor receptor.
Cancer research 1997;57(8):1447-51.
1997: Marcienne Wright; JE Grim; Jessy Deshane; M Kim; Theresa V Strong; Gene P Siegal; David T Curiel
An intracellular anti-erbB-2 single-chain antibody is specifically cytotoxic to human breast carcinoma cells overexpressing erbB-2.
Gene therapy 1997;4(4):317-22.
1997: Jessy Deshane; Gene P Siegal; Minghui Wang; Marcienne Wright; R Pat Bucy; Ronald D Alvarez; David T Curiel
Transductional efficacy and safety of an intraperitoneally delivered adenovirus encoding an anti-erbB-2 intracellular single-chain antibody for ovarian cancer gene therapy.
Gynecologic oncology 1997;64(3):378-85.
1997: Mack N Barnes; Jessy Deshane; M Rosenfeld; Gene P Siegal; David T Curiel; Ronald D Alvarez
Gene therapy and ovarian cancer: a review.
Obstetrics and gynecology 1997;89(1):145-55.
1996: M E Rosenfeld; Minghui Wang; Gene P Siegal; Ronald D Alvarez; Galina Mikheeva; Victor Krasnykh; David T Curiel
Adenoviral-mediated delivery of herpes simplex virus thymidine kinase results in tumor reduction and prolonged survival in a SCID mouse model of human ovarian carcinoma.
Journal of molecular medicine (Berlin, Germany) 1996;74(8):455-62.
1996: Mack N Barnes; Jessy Deshane; Gene P Siegal; Ronald D Alvarez; David T Curiel
Novel gene therapy strategy to accomplish growth factor modulation induces enhanced tumor cell chemosensitivity.
Clinical cancer research : an official journal of the American Association for Cancer Research 1996;2(7):1089-95.
1996: Jessy Deshane; JE Grim; S Loechel; Gene P Siegal; Ronald D Alvarez; David T Curiel
Intracellular antibody against erbB-2 mediates targeted tumor cell eradication by apoptosis.
Cancer gene therapy 1996;3(2):89-98.
1995: M E Rosenfeld; M Feng; S I Michael; Gene P Siegal; Ronald D Alvarez; David T Curiel
Adenoviral-mediated delivery of the herpes simplex virus thymidine kinase gene selectively sensitizes human ovarian carcinoma cells to ganciclovir.
Clinical cancer research : an official journal of the American Association for Cancer Research 1995;1(12):1571-80.
1995: Jessy Deshane; Gene P Siegal; Ronald D Alvarez; M H Wang; M Feng; G Cabrera; T Liu; M Kay; David T Curiel
Targeted tumor killing via an intracellular antibody against erbB-2.
The Journal of clinical investigation 1995;96(6):2980-9.
1995: Jessy Deshane; G Cabrera; JE Grim; Gene P Siegal; J Pike; Ronald D Alvarez; David T Curiel
Targeted eradication of ovarian cancer mediated by intracellular expression of anti-erbB-2 single-chain antibody.
Gynecologic oncology 1995;59(1):8-14.
1994: Jessy Deshane; F Loechel; Robert M Conry; Gene P Siegal; C R King; David T Curiel
Intracellular single-chain antibody directed against erbB2 down-regulates cell surface erbB2 and exhibits a selective anti-proliferative effect in erbB2 overexpressing cancer cell lines.
Gene therapy 1994;1(5):332-7.