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Paul Siegel

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Muge Akpinar-Elci; Kathleen Kreiss; Ju-Hyeong Park; Paul D Siegel; Alexis Visotcky; Sandra K White; Jean Cox-Ganser
Markers of upper airway inflammation associated with microbial exposure and symptoms in occupants of a water-damaged building.
Roni Munk; Denis Sasseville; Paul D Siegel; Brandon F Law; Linda Moreau
Thiurams in shoe contact dermatitis -- a case series.
Adam V Wisnewski; Justin Hettick; Jian Liu; Morgen Mhike; Paul D Siegel
Hexamethylene diisocyanate (HDI) vapor reactivity with glutathione and subsequent transfer to human albumin.

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2013: Muge Akpinar-Elci; Kathleen Kreiss; Ju-Hyeong Park; Paul D Siegel; Alexis Visotcky; Sandra K White; Jean Cox-Ganser
Markers of upper airway inflammation associated with microbial exposure and symptoms in occupants of a water-damaged building.
American journal of industrial medicine 2013;56(5):522-30.
2013: Roni Munk; Denis Sasseville; Paul D Siegel; Brandon F Law; Linda Moreau
Thiurams in shoe contact dermatitis -- a case series.
Contact dermatitis 2013;68(3):185-7.
2013: Adam V Wisnewski; Justin Hettick; Jian Liu; Morgen Mhike; Paul D Siegel
Hexamethylene diisocyanate (HDI) vapor reactivity with glutathione and subsequent transfer to human albumin.
Toxicology in vitro : an international journal published in association with BIBRA 2013;27(2):662-71.
2012: Justin Hettick; Jian Liu; Paul D Siegel; Brett James Green; Adam V Wisnewski
Vapor conjugation of toluene diisocyanate to specific lysines of human albumin.
Analytical biochemistry 2012;421(2):706-11.
2011: Tinashe B Ruwona; Detlef Schmechel; Donald Beezhold; Justin Hettick; Victor J Johnson; Reuben H Simoyi; Wei Wang; Paul D Siegel
Production, characterization and utility of a panel of monoclonal antibodies for the detection of toluene diisocyanate haptenated proteins.
Journal of immunological methods 2011;373(1-2):127-35.
2011: Adam V Wisnewski; Justin Hettick; Paul D Siegel
Toluene diisocyanate reactivity with glutathione across a vapor/liquid interface and subsequent transcarbamoylation of human albumin.
Chemical research in toxicology 2011;24(10):1686-93.
2011: Justin Hettick; Paul D Siegel
Determination of the toluene diisocyanate binding sites on human serum albumin by tandem mass spectrometry.
Analytical biochemistry 2011;414(2):232-8.
2011: Brett James Green; Justin Hettick; Kathleen Kreiss; Greg Kullman; W R Rittenour; Paul D Siegel; Francoise M Blachere; Toni A Bledsoe; Jean Cox-Ganser; Kristin J Cummings; Denise M Gaughan; Donald H Beezhold
Occupational sensitization to soy allergens in workers at a processing facility.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2011;41(7):1022-30.
2011: Amanda D Buskirk; Justin Hettick; Itai Chipinda; Brandon F Law; Paul D Siegel; James E Slaven; Brett James Green; Donald H Beezhold
Fungal pigments inhibit the matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis of darkly pigmented fungi.
Analytical biochemistry 2011;411(1):122-8.
2011: Itai Chipinda; Tinashe B Ruwona; Steven P Templeton; Paul D Siegel
Use of the human monocytic leukemia THP-1 cell line and co-incubation with microsomes to identify and differentiate hapten and prohapten sensitizers.
Toxicology 2011;280(3):135-43.
2011: Itai Chipinda; Justin Hettick; Paul D Siegel
Haptenation: chemical reactivity and protein binding.
Journal of allergy 2011;2011():839682.
2011: Stacey E Anderson; Paul D Siegel; B Jean Meade
The LLNA: A Brief Review of Recent Advances and Limitations.
Journal of allergy 2011;2011():424203.
2010: Brandon F Law; Justin Hettick; Jennifer Hornsby-Myers; Paul D Siegel
Reservations concerning second-hand fentanyl exposure in the operating room.
Journal of addictive diseases 2010;29(3):282-3.
2010: Tinashe B Ruwona; Victor J Johnson; Detlef Schmechel; Reuben H Simoyi; Donald Beezhold; Paul D Siegel
Monoclonal antibodies against toluene diisocyanate haptenated proteins from vapor-exposed mice.
Hybridoma (2005) 2010;29(3):221-9.
2010: Itai Chipinda; Risikat O Ajibola; Moshood K Morakinyo; Tinashe B Ruwona; Reuben H Simoyi; Paul D Siegel
Rapid and simple kinetics screening assay for electrophilic dermal sensitizers using nitrobenzenethiol.
Chemical research in toxicology 2010;23(5):918-25.
2010: Paul D Siegel; Brandon F Law; Joseph F Fowler; Lynn M Fowler
Disproportionated rosin dehydroabietic acid in neoprene surgical gloves.
Dermatitis : contact, atopic, occupational, drug : official journal of the American Contact Dermatitis Society, North American Contact Dermatitis Group 2010;21(3):157-9.
2010: Brandon F Law; Justin Hettick; Jennifer Hornsby-Myers; Paul D Siegel
Analytical methodology and assessment of potential second-hand exposure to fentanyl in the hospital surgical setting.
Journal of addictive diseases 2010;29(1):51-8.
2009: X D Zhang; A F Hubbs; Paul D Siegel
Changes in asthma-like responses after extended removal from exposure to trimellitic anhydride in the Brown Norway rat model.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2009;39(11):1746-53.
2009: Itai Chipinda; Stacey E Anderson; Leon F Butterworth; Donald H Beezhold; Paul D Siegel
Increased cell proliferation in spleen and lymph nodes peripheral to contact allergen application site.
Toxicology 2009;257(3):113-6.
2008: Itai Chipinda; Justin Hettick; Reuben H Simoyi; Paul D Siegel
Zinc diethyldithiocarbamate allergenicity: potential haptenation mechanisms.
Contact dermatitis 2008;59(2):79-89.
2008: Itai Chipinda; Xing-Dong Zhang; Reuben H Simoyi; Paul D Siegel
Mercaptobenzothiazole allergenicity-role of the thiol group.
Cutaneous and ocular toxicology 2008;27(2):103-16.
2007: L P Myers; B F Law; Adam Fedorowicz; Paul D Siegel; Leon F Butterworth; S E Anderson; Gordon L Sussman; M Shapiro; B Jean Meade; Donald H Beezhold
Identification of phenolic dermal sensitizers in a wound closure tape.
Journal of immunotoxicology 2007;4(4):303-10.
2007: Itai Chipinda; Justin Hettick; Reuben H Simoyi; Paul D Siegel
Oxidation of 2-mercaptobenzothiazole in latex gloves and its possible haptenation pathway.
Chemical research in toxicology 2007;20(8):1084-92.
2006: Justin Hettick; Michael Kashon; James E Slaven; Yan Ma; Janet P Simpson; Paul D Siegel; Gerald N Mazurek; David N Weissman
Discrimination of intact mycobacteria at the strain level: a combined MALDI-TOF MS and biostatistical analysis.
Proteomics 2006;6(24):6416-25.
2006: Xing-Dong Zhang; Michael Andrew; Ann F Hubbs; Paul D Siegel
Airway responses in Brown Norway rats following inhalation sensitization and challenge with trimellitic anhydride.
Toxicological sciences : an official journal of the Society of Toxicology 2006;94(2):322-9.
2006: Brandon F Law; Samuel Stone; David G Frazer; Paul D Siegel
Characterization of laboratory simulated road paving-like asphalt by high-performance liquid chromatography and gas chromatography-mass spectrometry.
Journal of occupational and environmental hygiene 2006;3(7):343-50.
2006: Itai Chipinda; Sarah J Stetson; Gary J Depree; Reuben H Simoyi; Paul D Siegel
Kinetics and mechanistic studies of the hydrolysis of diisocyanate-derived bis-thiocarbamates of cysteine methyl ester.
Chemical research in toxicology 2006;19(3):341-50.
2006: Olufunke Olagunju; Paul D Siegel; Oluwarotim Rotimi Olojo; Reuben H Simoyi
Oxyhalogen-sulfur chemistry: kinetics and mechanism of oxidation of N-acetylthiourea by chlorite and chlorine dioxide.
The journal of physical chemistry. A 2006;110(7):2396-410.
2005: Gary J Depree; T A Bledsoe; Paul D Siegel
Survey of sulfur-containing rubber accelerator levels in latex and nitrile exam gloves.
Contact dermatitis 2005;53(2):107-13.
2004: Justin Hettick; Michael Kashon; Janet P Simpson; Paul D Siegel; Gerald H Mazurek; David N Weissman
Proteomic profiling of intact mycobacteria by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Analytical chemistry 2004;76(19):5769-76.
2004: Gary J Depree; Paul D Siegel
Determination of 3-amino-5-mercapto-1,2,4-triazole in serum.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2004;801(2):359-62.
2004: HW Zhao; Xuejun J Yin; David G Frazer; Mark W Barger; Paul D Siegel; Lyndell Millecchia; BZ Zhong; Seth Tomblyn; Samuel Stone; Joseph K H Ma; Vincent Castranova; Jane Y C Ma
Effects of paving asphalt fume exposure on genotoxic and mutagenic activities in the rat lung.
Mutation research 2004;557(2):137-49.
2004: Paul D Siegel; Rajiv K Saxena; Queen B Saxena; Joseph K H Ma; Jane Y C Ma; Xuejun J Yin; Vincent Castranova; Nabil H Al-Humadi; Daniel M Lewis
Effect of diesel exhaust particulate (DEP) on immune responses: contributions of particulate versus organic soluble components.
Journal of toxicology and environmental health. Part A 2004;67(3):221-31.
2004: Gary J Depree; T A Bledsoe; Paul D Siegel
Determination of zinc dialkyldithiocarbamates in latex condoms.
Journal of chromatographic science 2004;42(2):80-4.
2004: Xing-Dong Zhang; Jeffrey S Fedan; Daniel M Lewis; Paul D Siegel
Asthmalike biphasic airway responses in Brown Norway rats sensitized by dermal exposure to dry trimellitic anhydride powder.
The Journal of allergy and clinical immunology 2004;113(2):320-6.
2003: Queen B Saxena; Rajiv K Saxena; Paul D Siegel; Daniel M Lewis
Identification of organic fractions of diesel exhaust particulate (DEP) which inhibit nitric oxide (NO) production from a murine macrophage cell line.
Toxicology letters 2003;143(3):317-22.
2003: Xuejun J Yin; Rosana Schafer; Jane Y C Ma; James M Antonini; Jenny R Roberts; David N Weissman; Paul D Siegel; Joseph K H Ma
Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). II. Effects of DEPs on T-cell-mediated immune responses in rats.
Environmental health perspectives 2003;111(4):524-30.
2002: Xuejun J Yin; Rosana Schafer; Jane Y C Ma; James M Antonini; David D Weissman; Paul D Siegel; Mark W Barger; Jenny R Roberts; Joseph K H Ma
Alteration of pulmonary immunity to Listeria monocytogenes by diesel exhaust particles (DEPs). I. Effects of DEPs on early pulmonary responses.
Environmental health perspectives 2002;110(11):1105-11.
2002: Jane Y C Ma; Hui-Min Yang; Mark W Barger; Paul D Siegel; BZ Zhong; A J Kriech; Vincent Castranova
Alteration of pulmonary cytochrome p-450 system: effects of asphalt fume condensate exposure.
Journal of toxicology and environmental health. Part A 2002;65(17):1247-60.
2002: Nabil H Al-Humadi; Joseph K H Ma; Daniel M Lewis; Jane Y C Ma; Mark W Barger; Paul D Siegel
Dose-dependent thiol and immune responses to ovalbumin challenge in Brown Norway rats.
Toxicology and industrial health 2002;18(7):343-52.
2002: X D Zhang; D K Murray; Daniel M Lewis; Paul D Siegel
Dose-response and time course of specific IgE and IgG after single and repeated topical skin exposure to dry trimellitic anhydride powder in a Brown Norway rat model.
Allergy 2002;57(7):620-6.
2002: Nabil H Al-Humadi; Paul D Siegel; Daniel M Lewis; Mark W Barger; Jane Y C Ma; David N Weissman; Joseph K H Ma
The effect of diesel exhaust particles (DEP) and carbon black (CB) on thiol changes in pulmonary ovalbumin allergic sensitized Brown Norway rats.
Experimental lung research 2002;28(5):333-49.
2002: Nabil H Al-Humadi; Paul D Siegel; Daniel M Lewis; Mark W Barger; Jane Y C Ma; David N Weissman; Joseph K H Ma
Alteration of intracellular cysteine and glutathione levels in alveolar macrophages and lymphocytes by diesel exhaust particle exposure.
Environmental health perspectives 2002;110(4):349-53.
2002: Xing Dong Zhang; Paul D Siegel; Daniel M Lewis
Immunotoxicology of organic acid anhydrides (OAAs).
International immunopharmacology 2002;2(2-3):239-48.
2001: BZ Zhong; Gary J Depree; Paul D Siegel
Differentiation of the mechanism of micronuclei induced by cysteine and glutathione conjugates of methylenedi-p-phenyl diisocyanate from that of 4,4'-methylenedianiline.
Mutation research 2001;497(1-2):29-37.
2001: J Wang; Daniel M Lewis; Vincent Castranova; David G Frazer; Travis Goldsmith; Seth Tomblyn; J Simpson; Samuel Stone; Aliakbar A Afshari; Paul D Siegel
Characterization of asphalt fume composition under simulated road paving conditions by GC/MS and microflow LC/quadrupole time-of-flight MS.
Analytical chemistry 2001;73(15):3691-700.
2000: BZ Zhong; Paul D Siegel
Induction of micronuclei following exposure to methylene di-phenyl diisocyanate: potential genotoxic metabolites.
Toxicological sciences : an official journal of the Society of Toxicology 2000;58(1):102-8.
2000: Edward L Petsonk; Mei-Lin Wang; Daniel M Lewis; Paul D Siegel; B J Husberg
Asthma-like symptoms in wood product plant workers exposed to methylene diphenyl diisocyanate.
Chest 2000;118(4):1183-93.
2000: Paul D Siegel; Nabil H Al-Humadi; Lyndell Millecchia; Victor A Robinson; Ann F Hubbs; E R Nelson; Jeffrey S Fedan
Ovalbumin aeroallergen exposure-response in Brown Norway rats.
Inhalation toxicology 2000;12(3):245-61.
1998: Mark A Woodin; Russ Hauser; Youcheng Liu; T J Smith; Paul D Siegel; D M Lewis; D J Tollerud; David C Christiani
Molecular markers of acute upper airway inflammation in workers exposed to fuel-oil ash.
American journal of respiratory and critical care medicine 1998;158(1):182-7.
1998: G J Kullman; Peter S Thorne; P F Waldron; J J Marx; B Ault; Daniel M Lewis; Paul D Siegel; Stephen A Olenchock; James Merchant
Organic dust exposures from work in dairy barns.
American Industrial Hygiene Association journal 1998;59(6):403-13.
1997: Paul D Siegel; Nabil H Al-Humadi; E R Nelson; Daniel M Lewis; Ann F Hubbs
Adjuvant effect of respiratory irritation on pulmonary allergic sensitization: time and site dependency.
Toxicology and applied pharmacology 1997;144(2):356-62.
1997: Ann F Hubbs; Vincent Castranova; Jane Y C Ma; David G Frazer; Paul D Siegel; B S Ducatman; Ardith Grote; Diane Schwegler-Berry; Victor A Robinson; C Van Dyke; Mark W Barger; J Xiang; J Parker
Acute lung injury induced by a commercial leather conditioner.
Toxicology and applied pharmacology 1997;143(1):37-46.
1994: Tracy Shahan; Paul D Siegel; W G Sorenson; W G Kuschner; Daniel M Lewis
A sensitive new bioassay for tumor necrosis factor.
Journal of immunological methods 1994;175(2):181-7.
1994: Paul D Siegel; E A Ronk; P R Clark; Tracy Shahan; Vincent Castranova
Measurement of environmental formylmethionyl-peptides.
Journal of toxicology and environmental health 1994;42(3):275-88.
1992: Paul D Siegel; Tracy Shahan; W G Sorenson
Analysis of environmental histamine from agricultural dust.
Scandinavian journal of work, environment & health 1992;18 Suppl 2():60-2.
1991: Paul D Siegel; Stephen A Olenchock; W G Sorenson; Daniel M Lewis; T A Bledsoe; J J May; D S Pratt
Histamine and endotoxin contamination of hay and respirable hay dust.
Scandinavian journal of work, environment & health 1991;17(4):276-80.
1990: Paul D Siegel; Daniel M Lewis; M Petersen; Stephen A Olenchock
Observations of the use of o-phthalaldehyde condensation for the measurement of histamine.
The Analyst 1990;115(8):1029-32.
1990: Paul D Siegel; Daniel M Lewis; Stephen A Olenchock
High-performance liquid chromatographic method for the evaluation of possible interferences in basophil-histamine release measurements.
Analytical biochemistry 1990;188(2):416-21.
1990: Paul D Siegel; Daniel M Lewis; Stephen A Olenchock
Neutrophil derived interference in the fluorometric determination of histamine.
International archives of allergy and applied immunology 1990;93(1):80-2.