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Michael Sieweke

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Noushine Mossadegh-Keller; Stephen L Nutt; Sandrine Sarrazin; Leon Espinosa; Prashanth K Kandalla; Jordan Moore; E Richard Stanley; Michael H Sieweke
M-CSF instructs myeloid lineage fate in single haematopoietic stem cells.
Sandrine Sarrazin; Michael H Sieweke
Integration of cytokine and transcription factor signals in hematopoietic stem cell commitment.
Salvatore Spicuglia; Guillaume Tibéri; Christelle Vincent-Fabert; Joaquin Zacarias-Cabeza; Touati Benoukraf; François Bertucci; Boris Calmels; Pierre Ferrier; David Grimwade; Ken Mills; AJ Saurin; Michael H Sieweke; E Duprez
Characterisation of genome-wide PLZF/RARA target genes.

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All Publications

2013: Noushine Mossadegh-Keller; Stephen L Nutt; Sandrine Sarrazin; Leon Espinosa; Prashanth K Kandalla; Jordan Moore; E Richard Stanley; Michael H Sieweke
M-CSF instructs myeloid lineage fate in single haematopoietic stem cells.
Nature 2013;497(7448):239-43.
2011: Sandrine Sarrazin; Michael H Sieweke
Integration of cytokine and transcription factor signals in hematopoietic stem cell commitment.
Seminars in immunology 2011;23(5):326-34.
2011: Salvatore Spicuglia; Guillaume Tibéri; Christelle Vincent-Fabert; Joaquin Zacarias-Cabeza; Touati Benoukraf; François Bertucci; Boris Calmels; Pierre Ferrier; David Grimwade; Ken Mills; AJ Saurin; Michael H Sieweke; E Duprez
Characterisation of genome-wide PLZF/RARA target genes.
PloS one 2011;6(9):e24176.
2010: Frederic Geissmann; Markus G Manz; Steffen Jung; Michael H Sieweke; Miriam Merad; Klaus Ley
Development of monocytes, macrophages, and dendritic cells.
Science (New York, N.Y.) 2010;327(5966):656-61.
2010: Michael H Sieweke
Creating a blood line from human skin.
Genome biology 2010;11(12):143.
2009: Athar Aziz; Erinn Soucie; Sandrine Sarrazin; Michael H Sieweke
MafB/c-Maf deficiency enables self-renewal of differentiated functional macrophages.
Science (New York, N.Y.) 2009;326(5954):867-71.
2009: Sandrine Sarrazin; Noushine Mossadegh-Keller; Taro Fukao; Athar Aziz; Frederic Mourcin; Laurent Vanhille; Louise Kelly Modis; Philippe Kastner; Susan Chan; Estelle Duprez; Claas Otto; Michael H Sieweke
MafB restricts M-CSF-dependent myeloid commitment divisions of hematopoietic stem cells.
Cell 2009;138(2):300-13.
2009: Cedric Auffray; Michael H Sieweke; Frederic Geissmann
Blood monocytes: development, heterogeneity, and relationship with dendritic cells.
Annual review of immunology 2009;27():669-92.
2008: Ekaterina P Lamber; Laurent Vanhille; Larissa C Textor; Galina S Kachalova; Michael H Sieweke; Matthias Wilmanns
Regulation of the transcription factor Ets-1 by DNA-mediated homo-dimerization.
The EMBO journal 2008;27(14):2006-17.
2007: Silke Tillmanns; Claas Otto; Ellis Jaffray; Camille Du Roure; Youssef BAKRI; Laurent Vanhille; Sandrine Sarrazin; Ron Thomas Hay; Michael H Sieweke
SUMO modification regulates MafB-driven macrophage differentiation by enabling Myb-dependent transcriptional repression.
Molecular and cellular biology 2007;27(15):5554-64.
2007: Isabella Artner; Bruno Blanchi; Jeffrey C Raum; Min Guo; Tomomi Kaneko; Sabine Cordes; Michael H Sieweke; Roland Stein
MafB is required for islet beta cell maturation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(10):3853-8.
2006: Athar Aziz; Laurent Vanhille; Peer Mohideen; Louise M Kelly; Claas Otto; Youssef BAKRI; Noushine Mossadegh; Sandrine Sarrazin; Michael H Sieweke
Development of macrophages with altered actin organization in the absence of MafB.
Molecular and cellular biology 2006;26(18):6808-18.
2005: Youssef BAKRI; Sandrine Sarrazin; Ulrich P Mayer; Silke Tillmanns; Claus Nerlov; Annie Boned; Michael H Sieweke
Balance of MafB and PU.1 specifies alternative macrophage or dendritic cell fate.
Blood 2005;105(7):2707-16.
2005: Bruno Blanchi; Michael H Sieweke
Mutations of brainstem transcription factors and central respiratory disorders.
Trends in molecular medicine 2005;11(1):23-30.
2003: Bruno Blanchi; Louise M Kelly; Jean-Charles Viemari; Isabelle Lafon; Henri Burnet; Michelle Bévengut; Silke Tillmanns; Laurent Daniel; Thomas Graf; Gérard Hilaire; Michael H Sieweke
MafB deficiency causes defective respiratory rhythmogenesis and fatal central apnea at birth.
Nature neuroscience 2003;6(10):1091-100.
2003: Gerd Elvert; Andreas Kappel; Regina Heidenreich; Ursula Englmeier; Stephan Lanz; Till Acker; Manuel Rauter; Karl H Plate; Michael H Sieweke; Georg Breier; Ingo Flamme
Cooperative interaction of hypoxia-inducible factor-2alpha (HIF-2alpha ) and Ets-1 in the transcriptional activation of vascular endothelial growth factor receptor-2 (Flk-1).
The Journal of biological chemistry 2003;278(9):7520-30.
2003: Gérard Hilaire; Henri Burnet; Krzysztof Ptak; Michael H Sieweke; Bruno Blanchi; Carmen De Felipe; Stephen Hunt; Roger Monteau
Deletion of tachykinin NK1 receptor gene in mice does not alter respiratory network maturation but alters respiratory responses to hypoxia.
Advances in experimental medicine and biology 2003;536():497-504.
2002: Krzysztof Ptak; Henri Burnet; Bruno Blanchi; Michael H Sieweke; Carmen De Felipe; Stephen P Hunt; Roger Monteau; Gérard Hilaire
The murine neurokinin NK1 receptor gene contributes to the adult hypoxic facilitation of ventilation.
The European journal of neuroscience 2002;16(12):2245-52.
2000: Roberto Posada; Massimo Pettoello-Mantovani; Michael H Sieweke; Thomas Graf; Harris Goldstein
Suppression of HIV type 1 replication by a dominant-negative Ets-1 mutant.
AIDS research and human retroviruses 2000;16(18):1981-9.
2000: Louise M Kelly; Ursula Englmeier; I Lafon; Michael H Sieweke; Thomas Graf
MafB is an inducer of monocytic differentiation.
The EMBO journal 2000;19(9):1987-97.
1999: W Y Kim; Michael H Sieweke; E Ogawa; Hee-Jun Wee; Ursula Englmeier; Thomas Graf; Yoshiaki Ito
Mutual activation of Ets-1 and AML1 DNA binding by direct interaction of their autoinhibitory domains.
The EMBO journal 1999;18(6):1609-20.
1998: Michael H Sieweke; Thomas Graf
A transcription factor party during blood cell differentiation.
Current opinion in genetics & development 1998;8(5):545-51.
1998: Kelly M McNagny; Michael H Sieweke; G Döderlein; Thomas Graf; Claus Nerlov
Regulation of eosinophil-specific gene expression by a C/EBP-Ets complex and GATA-1.
The EMBO journal 1998;17(13):3669-80.
1998: A Grapin-Botton; Marie-Ange Bonnin; Michael H Sieweke; Nicole M Le Douarin
Defined concentrations of a posteriorizing signal are critical for MafB/Kreisler segmental expression in the hindbrain.
Development (Cambridge, England) 1998;125(7):1173-81.
1998: Michael H Sieweke; H Tekotte; U Jarosch; Thomas Graf
Cooperative interaction of ets-1 with USF-1 required for HIV-1 enhancer activity in T cells.
The EMBO journal 1998;17(6):1728-39.
1997: Anne Eichmann; A Grapin-Botton; L Kelly; Thomas Graf; Nicole M Le Douarin; Michael H Sieweke
The expression pattern of the mafB/kr gene in birds and mice reveals that the kreisler phenotype does not represent a null mutant.
Mechanisms of development 1997;65(1-2):111-22.
1997: Michael H Sieweke; H Tekotte; Jon Frampton; Thomas Graf
MafB represses erythroid genes and differentiation through direct interaction with c-Ets-1.
Leukemia 1997;11 Suppl 3():486-8.
1996: Michael H Sieweke; H Tekotte; Jon Frampton; Thomas Graf
MafB is an interaction partner and repressor of Ets-1 that inhibits erythroid differentiation.
Cell 1996;85(1):49-60.
1995: Jon Frampton; Kelly M McNagny; Michael H Sieweke; A Philip; G Smith; Thomas Graf
v-Myb DNA binding is required to block thrombocytic differentiation of Myb-Ets-transformed multipotent haematopoietic progenitors.
The EMBO journal 1995;14(12):2866-75.