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Christopher Silliman

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Karen K Lo; Biswantha Patra; Christopher C Silliman; Douglas D Benson; Erik A Bey; David A Boothman; Carlton C Barnett
Hemoglobin-based oxygen carrier mitigates transfusion-mediated pancreas cancer progression.
Luis Lee; Ernest E Moore; Christopher C Silliman; James G Chandler; Kirk Hansen; Anirban Banerjee
It's not your grandfather's field plasma.
Anirban Banerjee; Jeffrey L Johnson; Wilbert L Jones; Luis Lee; Nathan J McLaughlin; Ernest E Moore; Trevor L Nydam; Christopher C Silliman
Hyperosmolarity attenuates TNF-α-mediated proinflammatory activation of human pulmonary microvascular endothelial cells.

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2013: Karen K Lo; Biswantha Patra; Christopher C Silliman; Douglas D Benson; Erik A Bey; David A Boothman; Carlton C Barnett
Hemoglobin-based oxygen carrier mitigates transfusion-mediated pancreas cancer progression.
Annals of surgical oncology 2013;20(6):2073-7.
2013: Luis Lee; Ernest E Moore; Christopher C Silliman; James G Chandler; Kirk Hansen; Anirban Banerjee
It's not your grandfather's field plasma.
Surgery 2013;153(6):857-60.
2013: Anirban Banerjee; Jeffrey L Johnson; Wilbert L Jones; Luis Lee; Nathan J McLaughlin; Ernest E Moore; Trevor L Nydam; Christopher C Silliman
Hyperosmolarity attenuates TNF-α-mediated proinflammatory activation of human pulmonary microvascular endothelial cells.
Shock (Augusta, Ga.) 2013;39(4):366-72.
2013: Jeffrey N Harr; Ernest E Moore; Christopher C Silliman; Max V Wohlauer; Anirban Banerjee; Theresa L Chin; Arsen Ghasabyan; Eduardo Gonzalez; Angela Sauaia
Platelets are dominant contributors to hypercoagulability after injury.
The journal of trauma and acute care surgery 2013;74(3):756-62; discussion 762-5.
2013: Jeffrey N Harr; Jeffrey Johnson; Ronald Maier; Ernest E Moore; Anirban Banerjee; Theresa L Chin; Joseph Cuschieri; Christopher C Silliman; Jason Sperry; Max V Wohlauer; Angela Sauaia
Antiplatelet therapy is associated with decreased transfusion-associated risk of lung dysfunction, multiple organ failure, and mortality in trauma patients.
Critical care medicine 2013;41(2):399-404.
2013: Jeffrey N Harr; Ernest E Moore; Angela Sauaia; Anirban Banerjee; Theresa L Chin; Arsen Ghasabyan; Christopher C Silliman
Functional fibrinogen assay indicates that fibrinogen is critical in correcting abnormal clot strength following trauma.
Shock (Augusta, Ga.) 2013;39(1):45-9.
2013: Annette Vetlesen; Mohammad Reza Mirlashari; Christopher C Silliman; Ciğdem Akalın Akkök; Marguerite R Kelher; Samina Y Khan; Jens Kjeldsen-Kragh
Biological response modifiers in photochemically pathogen-reduced versus untreated apheresis platelet concentrates.
Transfusion 2013;53(1):147-55.
2012: Max Wohlauer; Frank Wright; Frank Accurso; Miguel Fragoso; David Fullerton; Fabia Gamboni; James Haenel; Jeffrey Harr; Ernest E Moore; Christopher C Silliman; Anirban Banerjee
Nebulized hypertonic saline attenuates acute lung injury following trauma and hemorrhagic shock via inhibition of matrix metalloproteinase-13.
Critical care medicine 2012;40(9):2647-53.
2012: Jeffrey N Harr; Wilbert L Jones; Ernest E Moore; Christopher C Silliman; John Stringham; Max V Wohlauer; Miguel Fragoso; Fabia Gamboni; Anirban Banerjee
Isoflurane prevents acute lung injury through ADP-mediated platelet inhibition.
Surgery 2012;152(2):270-6.
2012: Christopher C Silliman; Marguerite R Kelher; Daniel R Ambruso
Bioactive lipids from stored cellular blood components: in vitro method is crucial for proper interpretation.
Transfusion 2012;52(5):1155-7; author reply 1157-8.
2012: Max V Wohlauer; Francis J Castellino; Ed Evans; Jeffrey Harr; Ernest E Moore; Victoria Ploplis; Angela Sauaia; Christopher C Silliman; Scott Thomas; Mark Walsh
Early platelet dysfunction: an unrecognized role in the acute coagulopathy of trauma.
Journal of the American College of Surgeons 2012;214(5):739-46.
2012: Luis Lee; Ernest E Moore; Anirban Banerjee; Marguerite R Kelher; Christopher C Silliman
Hypertonic saline inhibits arachidonic acid priming of the human neutrophil oxidase.
The Journal of surgical research 2012;174(1):24-8.
2012: Max Valentin Wohlauer; Nathan M Droz; Miguel Fragoso; Eduardo Gonzalez; Jeffrey Harr; Ernest E Moore; Christopher C Silliman
Hemodilution is not critical in the pathogenesis of the acute coagulopathy of trauma.
The Journal of surgical research 2012;173(1):26-30.
2012: Fredric M Pieracci; Nicole Townsend; Carlton C Barnett; Denis D Bensard; Walter Biffl; Clay C Burlew; Andrew Gerber; Jeffery Johnson; Ernest E Moore; Christopher C Silliman
Sexual dimorphism in hematocrit response following red blood cell transfusion of critically ill surgical patients.
ISRN hematology 2012;2012():298345.
2011: Jeffrey N Harr; Xiayuan Liang; Ernest E Moore; Anirban Banerjee; Miguel Fragoso; Fabia Gamboni; Max V Wohlauer; Christopher C Silliman
Activated platelets in heparinized shed blood: the "second hit" of acute lung injury in trauma/hemorrhagic shock models.
Shock (Augusta, Ga.) 2011;36(6):595-603.
2011: Max V Wohlauer; Miguel Fragoso; Eduardo Gonzalez; Jeffrey Harr; Ernest E Moore; Christopher C Silliman
A standardized technique for performing thromboelastography in rodents.
Shock (Augusta, Ga.) 2011;36(5):524-6.
2011: Jeffrey N Harr; Ernest E Moore; Anirban Banerjee; Nathan Droz; Miguel Fragoso; Max V Wohlauer; Christopher C Silliman
The acute coagulopathy of trauma is due to impaired initial thrombin generation but not clot formation or clot strength.
The Journal of surgical research 2011;170(2):319-24.
2011: Max Valentin Wohlauer; Anirban Banerjee; John Eun; Miguel Fragoso; Jeffrey Harr; Ernest E Moore; Christopher C Silliman
Cross-transfusion of postshock mesenteric lymph provokes acute lung injury.
The Journal of surgical research 2011;170(2):314-8.
2011: Lindsey Micel; Rachelle Nuss; Laura Fenton; Mark Lovell; Christopher C Silliman
Non-palpable splenic enlargement as the etiology of abdominal pain in an adolescent with hemoglobin SC disease.
Pediatric blood & cancer 2011;57(2):352-3.
2011: Monika Dzieciatkowska; Max V Wohlauer; Ernest E Moore; Sagar S Damle; Erik Peltz; Jeffrey Campsen; Marguerite R Kelher; Christopher C Silliman; Anirban Banerjee; Kirk Hansen
Proteomic analysis of human mesenteric lymph.
Shock (Augusta, Ga.) 2011;35(4):331-8.
2011: John C Eun; Ernest E Moore; Anirban Banerjee; Marguerite R Kelher; Samina Y Khan; David J Elzi; Nathan J D McLaughlin; Christopher C Silliman
Leukotriene b4 and its metabolites prime the neutrophil oxidase and induce proinflammatory activation of human pulmonary microvascular endothelial cells.
Shock (Augusta, Ga.) 2011;35(3):240-4.
2011: Alexander B Benson; James R Burton; Gregory L Austin; Scott W Biggins; Michael A Zimmerman; Igal Kam; Susan Mandell; Christopher C Silliman; Hugo Rosen; Marc Moss
Differential effects of plasma and red blood cell transfusions on acute lung injury and infection risk following liver transplantation.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2011;17(2):149-58.
2010: Samina Y Khan; Nathan J D McLaughlin; Marguerite R Kelher; Phillip Eckels; Fabia Gamboni-Robertson; Anirban Banerjee; Christopher C Silliman
Lysophosphatidylcholines activate G2A inducing G(αi)₋₁-/G(αq/)₁₁- Ca²(+) flux, G(βγ)-Hck activation and clathrin/β-arrestin-1/GRK6 recruitment in PMNs.
The Biochemical journal 2010;432(1):35-45.
2010: Peter K Moore; Douglas Benson; Marguerite Kehler; Ernest E Moore; Miguel Fragoso; Christopher C Silliman; Carlton C Barnett
The plasma fraction of stored erythrocytes augments pancreatic cancer metastasis in male versus female mice.
The Journal of surgical research 2010;164(1):23-7.
2010: Douglas D Benson; Marguerite R Kelher; Xianzhong Meng; David A Fullerton; Joon H Lee; Christopher C Silliman; Carlton C Barnett
Gender-specific transfusion affects tumor-associated neutrophil: macrophage ratios in murine pancreatic adenocarcinoma.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2010;14(10):1560-5.
2010: Alexander B Benson; Gregory L Austin; Mary Berg; Kim K McFann; Sila Thomas; Gina Ramirez; Hugo Rosen; Christopher C Silliman; Marc Moss
Transfusion-related acute lung injury in ICU patients admitted with gastrointestinal bleeding.
Intensive care medicine 2010;36(10):1710-7.
2010: Eduardo Gonzalez; Jeffry L Kashuk; Ernest E Moore; Christopher C Silliman
Differentiation of enzymatic from platelet hypercoagulability using the novel thrombelastography parameter delta (delta).
The Journal of surgical research 2010;163(1):96-101.
2010: Carlton C Barnett; Adam W Beck; Shane E Holloway; Marguerite Kehler; Marie K Schluterman; Rolf A Brekken; Jason B Fleming; Christopher C Silliman
Intravenous delivery of the plasma fraction of stored packed erythrocytes promotes pancreatic cancer growth in immunocompetent mice.
Cancer 2010;116(16):3862-74.
2010: Christopher C Silliman; Marguerite R Kelher; Fabia Gamboni-Robertson; Christine Hamiel; Kelly M England; Charles A Dinarello; Travis H Wyman; Samina Y Khan; Nathan J D McLaughlin; Rachel S Bercovitz; Anirban Banerjee
Tumor necrosis factor-alpha causes release of cytosolic interleukin-18 from human neutrophils.
American journal of physiology. Cell physiology 2010;298(3):C714-24.
2009: Christopher C Silliman; Yoke Lin Fung; J Bradley Ball; Samina Y Khan
Transfusion-related acute lung injury (TRALI): current concepts and misconceptions.
Blood reviews 2009;23(6):245-55.
2009: Alexander B Benson; Marc Moss; Christopher C Silliman
Transfusion-related acute lung injury (TRALI): a clinical review with emphasis on the critically ill.
British journal of haematology 2009;147(4):431-43.
2009: Phillip C Eckels; Anirban Banerjee; Ernest E Moore; Nathan J D McLaughlin; Lynn M Gries; Marguerite R Kelher; Kelly M England; Fabia Gamboni-Robertson; Samina Y Khan; Christopher C Silliman
Amantadine inhibits platelet-activating factor induced clathrin-mediated endocytosis in human neutrophils.
American journal of physiology. Cell physiology 2009;297(4):C886-97.
2009: Erik D Peltz; Ernest E Moore; Phillip C Eckels; Sagar S Damle; Yuko Tsuruta; Jeffrey L Johnson; Angela Sauaia; Christopher C Silliman; Anirban Banerjee; Edward Abraham
HMGB1 is markedly elevated within 6 hours of mechanical trauma in humans.
Shock (Augusta, Ga.) 2009;32(1):17-22.
2009: Joel M Baumgartner; Trevor L Nydam; Jason H Clarke; Anirban Banerjee; Christopher C Silliman; Martin D McCarter
Red blood cell supernatant potentiates LPS-induced proinflammatory cytokine response from peripheral blood mononuclear cells.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2009;29(6):333-8.
2009: Jonathan P Roach; Ernest E Moore; David A Partrick; Sagar S Damle; Christopher C Silliman; Robert C McIntyre; Anirban Banerjee
Heme oxygenase-1 induction in macrophages by a hemoglobin-based oxygen carrier reduces endotoxin-stimulated cytokine secretion.
Shock (Augusta, Ga.) 2009;31(3):251-7.
2009: Marguerite R Kelher; Tomhiko Masuno; Ernest E Moore; Sagar Damle; Xianzhong Meng; Yong Song; Xiayuan Liang; Jerry Niedzinski; Steven S Geier; Samina Y Khan; Fabia Gamboni-Robertson; Christopher C Silliman
Plasma from stored packed red blood cells and MHC class I antibodies causes acute lung injury in a 2-event in vivo rat model.
Blood 2009;113(9):2079-87.
2009: Joel M Baumgartner; Christopher C Silliman; Ernest E Moore; Anirban Banerjee; Martin D McCarter
Stored red blood cell transfusion induces regulatory T cells.
Journal of the American College of Surgeons 2009;208(1):110-9.
2008: Julie Kanter; Samina Y Khan; Marguerite Kelher; Lia Gore; Christopher C Silliman
Oncogenic and angiogenic growth factors accumulate during routine storage of apheresis platelet concentrates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(12):3942-7.
2008: Nathan J D McLaughlin; Anirban Banerjee; Samina Y Khan; Janet L Lieber; Marguerite R Kelher; Fabia Gamboni-Robertson; Forest R Sheppard; Ernest E Moore; Gary W Mierau; David J Elzi; Christopher C Silliman
Platelet-activating factor-mediated endosome formation causes membrane translocation of p67phox and p40phox that requires recruitment and activation of p38 MAPK, Rab5a, and phosphatidylinositol 3-kinase in human neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(12):8192-203.
2008: Janeen R Jordan; Ernest E Moore; Eric L Sarin; Sagar S Damle; Sara B Kashuk; Christopher C Silliman; Anirban Banerjee
Arachidonic acid in postshock mesenteric lymph induces pulmonary synthesis of leukotriene B4.
Journal of applied physiology (Bethesda, Md. : 1985) 2008;104(4):1161-6.
2007: Christopher C Silliman; Brian Curtis; Patricia M Kopko; Samina Y Khan; Marguerite R Kelher; Randy M Schuller; Baindu Sannoh; Daniel R Ambruso
Donor antibodies to HNA-3a implicated in TRALI reactions prime neutrophils and cause PMN-mediated damage to human pulmonary microvascular endothelial cells in a two-event in vitro model.
Blood 2007;109(4):1752-5.
2006: Samina Yasmin Khan; Marguerite R Kelher; Joanna M Heal; Neil Blumberg; Lynn K Boshkov; Richard Phipps; Kelly F Gettings; Nathan J D McLaughlin; Christopher C Silliman
Soluble CD40 ligand accumulates in stored blood components, primes neutrophils through CD40, and is a potential cofactor in the development of transfusion-related acute lung injury.
Blood 2006;108(7):2455-62.
2006: Nathan J D McLaughlin; Anirban Banerjee; Marguerite R Kelher; Fabia Gamboni-Robertson; Christine Hamiel; Forest R Sheppard; Ernest E Moore; Christopher C Silliman
Platelet-activating factor-induced clathrin-mediated endocytosis requires beta-arrestin-1 recruitment and activation of the p38 MAPK signalosome at the plasma membrane for actin bundle formation.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):7039-50.
2006: Christopher C Silliman
The two-event model of transfusion-related acute lung injury.
Critical care medicine 2006;34(5 Suppl):S124-31.
2006: Christopher C Silliman; Nathan J D McLaughlin
Transfusion-related acute lung injury.
Blood reviews 2006;20(3):139-59.
2006: Christopher C Silliman; Michael Wang
The merits of in vitro versus in vivo modeling in investigation of the immune system.
Environmental toxicology and pharmacology 2006;21(2):123-34.
2005: Forest R Sheppard; Marguerite R Kelher; Ernest E Moore; Nathan J D McLaughlin; Anirban Banerjee; Christopher C Silliman
Structural organization of the neutrophil NADPH oxidase: phosphorylation and translocation during priming and activation.
Journal of leukocyte biology 2005;78(5):1025-42.
2005: Michael Wang; Taru Hays; Daniel R Ambruso; Christopher C Silliman; William C Dickey
Hemolytic disease of the newborn caused by a high titer anti-group B IgG from a group A mother.
Pediatric blood & cancer 2005;45(6):861-2.
2005: Christopher C Silliman; Marguerite R Kelher
The role of endothelial activation in the pathogenesis of transfusion-related acute lung injury.
Transfusion 2005;45(2 Suppl):109S-116S.
2005: Forest R Sheppard; Ernest E Moore; Nathan J D McLaughlin; Marguerite R Kelher; Jeffrey L Johnson; Christopher C Silliman
Clinically relevant osmolar stress inhibits priming-induced PMN NADPH oxidase subunit translocation.
The Journal of trauma 2005;58(4):752-7; discussion 757.
2005: Pearl Toy; Mark A Popovsky; Edward Abraham; Daniel R Ambruso; Leslie G Holness; Patricia M Kopko; Janice G McFarland; Avery B Nathens; Christopher C Silliman; David Stroncek
Transfusion-related acute lung injury: definition and review.
Critical care medicine 2005;33(4):721-6.
2005: Christopher C Silliman; Daniel R Ambruso; Lynn K Boshkov
Transfusion-related acute lung injury.
Blood 2005;105(6):2266-73.
2004: Eric L Sarin; Ernest E Moore; John B Moore; Tomohiko Masuno; Jessica L Moore; Anirban Banerjee; Christopher C Silliman
Systemic neutrophil priming by lipid mediators in post-shock mesenteric lymph exists across species.
The Journal of trauma 2004;57(5):950-4.
2004: Forest R Sheppard; Ernest E Moore; Jeffrey L Johnson; Aaron M Cheng; Nathan J D McLaughlin; Christopher C Silliman
Transfusion-induced leukocyte IL-8 gene expression is avoided by the use of human polymerized hemoglobin.
The Journal of trauma 2004;57(4):720-4; discussion 724-5.
2004: R B Covin; Daniel R Ambruso; Kelly M England; Marguerite R Kelher; Z Mehdizadehkashi; Lynn K Boshkov; Tomohiko Masuno; Ernest E Moore; F J Kim; Christopher C Silliman
Hypotension and acute pulmonary insufficiency following transfusion of autologous red blood cells during surgery: a case report and review of the literature.
Transfusion medicine (Oxford, England) 2004;14(5):375-83.
2003: Marguerite R Kelher; Daniel R Ambruso; David J Elzi; Steven M Anderson; Andrew J Paterson; Gail Thurman; Christopher C Silliman
Formyl-Met-Leu-Phe induces calcium-dependent tyrosine phosphorylation of Rel-1 in neutrophils.
Cell calcium 2003;34(6):445-55.
2003: Joao B Rezende-Neto; Ernest E Moore; Tomohiko Masuno; Peter K Moore; Jeffrey L Johnson; Forest R Sheppard; Jose R Cunha-Melo; Christopher C Silliman
The abdominal compartment syndrome as a second insult during systemic neutrophil priming provokes multiple organ injury.
Shock (Augusta, Ga.) 2003;20(4):303-8.
2003: Christopher C Silliman; R Weslie Tyson; Qi Wei; Frederick G Karrer; Stella M Davies; Marilyn Blake; Loris McGavran
Acute Philadelphia chromosome-positive leukemia in an adolescent boy after liver transplantation.
Journal of pediatric hematology/oncology 2003;25(7):565-8.
2003: Christopher C Silliman; A Jason Bjornsen; Travis H Wyman; Marguerite R Kelher; Jenny Allard; Sarah Bieber; Norbert F Voelkel
Plasma and lipids from stored platelets cause acute lung injury in an animal model.
Transfusion 2003;43(5):633-40.
2003: Christopher C Silliman; David J Elzi; Daniel R Ambruso; René J P Musters; Christine Hamiel; Ronald J Harbeck; Andrew J Paterson; A Jason Bjornsen; Travis H Wyman; Marguerite R Kelher; Kelly M England; Nathan McLaughlin-Malaxecheberria; Carlton C Barnett; Junichi Aiboshi; Anirban Bannerjee
Lysophosphatidylcholines prime the NADPH oxidase and stimulate multiple neutrophil functions through changes in cytosolic calcium.
Journal of leukocyte biology 2003;73(4):511-24.
2003: Ricardo J Gonzalez; Ernest E Moore; David J Ciesla; Joao R Nieto; Jeffrey L Johnson; Christopher C Silliman
Post-hemorrhagic shock mesenteric lymph activates human pulmonary microvascular endothelium for in vitro neutrophil-mediated injury: the role of intercellular adhesion molecule-1.
The Journal of trauma 2003;54(2):219-23.
2003: Christopher C Silliman; Lynn K Boshkov; Zahra Mehdizadehkashi; David J Elzi; William O Dickey; Linda Podlosky; Gwen Clarke; Daniel R Ambruso
Transfusion-related acute lung injury: epidemiology and a prospective analysis of etiologic factors.
Blood 2003;101(2):454-62.
2003: Jeffrey L Johnson; Ernest E Moore; Ricardo J Gonzalez; Nikki Fedel; David A Partrick; Christopher C Silliman
Alteration of the postinjury hyperinflammatory response by means of resuscitation with a red cell substitute.
The Journal of trauma 2003;54(1):133-9; discussion 139-40.
2002: Casey M Calkins; Denis D Bensard; Ernest E Moore; Robert C McIntyre; Christopher C Silliman; Walter L Biffl; Alden H Harken; David A Partrick; Patrick J Offner
The injured child is resistant to multiple organ failure: a different inflammatory response?
The Journal of trauma 2002;53(6):1058-63.
2002: Travis H Wyman; A Jason Bjornsen; David J Elzi; C Wayne Smith; Kelly M England; Marguerite R Kelher; Christopher C Silliman
A two-insult in vitro model of PMN-mediated pulmonary endothelial damage: requirements for adherence and chemokine release.
American journal of physiology. Cell physiology 2002;283(6):C1592-603.
2002: orest R Sheppard; Ernest E Moore; John Ryder; Alden H Harken; Joao B Rezende-Neto; Anirban Banerjee; Christopher C Silliman
"Primed" human neutrophils on a standard peripheral blood smear.
Journal of the American College of Surgeons 2002;195(5):731.
2002: Christopher C Silliman; Ernest E Moore; Garret S Zallen; Ricardo Gonzalez; Jeffrey L Johnson; David J Elzi; Xianzhong Meng; Kohji Hanasaki; Jun Ishizaki; Hitoshi Arita; Lihua Ao; Kelly M England; Anirban Banerjee
Presence of the M-type sPLA(2) receptor on neutrophils and its role in elastase release and adhesion.
American journal of physiology. Cell physiology 2002;283(4):C1102-13.
2002: Travis H Wyman; Charles A Dinarello; Anirban Banerjee; Fabia Gamboni-Robertson; Andrew A Hiester; Kelly M England; Marguerite R Kelher; Christopher C Silliman
Physiological levels of interleukin-18 stimulate multiple neutrophil functions through p38 MAP kinase activation.
Journal of leukocyte biology 2002;72(2):401-9.
2002: Ricardo J Gonzalez; Ernest E Moore; David J Ciesla; Joao Rezende Neto; Walter L Biffl; Christopher C Silliman
Hyperosmolarity abrogates neutrophil cytotoxicity provoked by post-shock mesenteric lymph.
Shock (Augusta, Ga.) 2002;18(1):29-32.
2002: Douglas Y Tamura; Ernest E Moore; David A Partrick; Jeffrey L Johnson; Patrick J Offner; Christopher C Silliman
Acute hypoxemia in humans enhances the neutrophil inflammatory response.
Shock (Augusta, Ga.) 2002;17(4):269-73.
2001: Ricardo J Gonzalez; Ernest E Moore; David J Ciesla; Walter L Biffl; Jeffrey L Johnson; Christopher C Silliman
Mesenteric lymph is responsible for post-hemorrhagic shock systemic neutrophil priming.
The Journal of trauma 2001;51(6):1069-72.
2001: David J Ciesla; Ernest E Moore; Walter L Biffl; Ricardo J Gonzalez; H B Moore; Christopher C Silliman
Hypertonic saline activation of p38 MAPK primes the PMN respiratory burst.
Shock (Augusta, Ga.) 2001;16(4):285-9.
2001: Ricardo J Gonzalez; Ernest E Moore; David J Ciesla; X Meng; Walter L Biffl; Christopher C Silliman
Post-hemorrhagic shock mesenteric lymph lipids prime neutrophils for enhanced cytotoxicity via phospholipase A2.
Shock (Augusta, Ga.) 2001;16(3):218-22.
2001: Ricardo J Gonzalez; Ernest E Moore; David J Ciesla; Walter L Biffl; Patrick J Offner; Christopher C Silliman
Phospholipase A(2)--derived neutral lipids from posthemorrhagic shock mesenteric lymph prime the neutrophil oxidative burst.
Surgery 2001;130(2):198-203.
2001: Carlton C Barnett; E E Moore; Christopher C Silliman; Eddie K Abdalla; David A Partrick; Steven A Curley
Cytosolic phospholipase A(2)-mediated ICAM-1 expression is calcium dependent.
The Journal of surgical research 2001;99(2):307-10.
2001: David J Elzi; A Jason Bjornsen; T MacKenzie; Travis H Wyman; Christopher C Silliman
Ionomycin causes activation of p38 and p42/44 mitogen-activated protein kinases in human neutrophils.
American journal of physiology. Cell physiology 2001;281(1):C350-60.
2001: David A Partrick; E E Moore; Christopher C Silliman; Carlton C Barnett; F A Kuypers
Secretory phospholipase A2 activity correlates with postinjury multiple organ failure.
Critical care medicine 2001;29(5):989-93.
2001: David J Ciesla; Ernest E Moore; Walter L Biffl; Ricardo J Gonzalez; Christopher C Silliman
Hypertonic saline attenuation of the neutrophil cytotoxic response is reversed upon restoration of normotonicity and reestablished by repeated hypertonic challenge.
Surgery 2001;129(5):567-75.
2001: Junichi Aiboshi; Ernest E Moore; David J Ciesla; Christopher C Silliman
Blood transfusion and the two-insult model of post-injury multiple organ failure.
Shock (Augusta, Ga.) 2001;15(4):302-6.
2001: Jeffrey L Johnson; Ernest E Moore; Patrick J Offner; David A Partrick; Douglas Y Tamura; Garret S Zallen; Christopher C Silliman
Resuscitation with a blood substitute abrogates pathologic postinjury neutrophil cytotoxic function.
The Journal of trauma 2001;50(3):449-55; discussion 456.
2001: Walter L Biffl; Ernest E Moore; Patrick J Offner; David J Ciesla; Ricardo J Gonzalez; Christopher C Silliman
Plasma from aged stored red blood cells delays neutrophil apoptosis and primes for cytotoxicity: abrogation by poststorage washing but not prestorage leukoreduction.
The Journal of trauma 2001;50(3):426-31; discussion 432.
2001: Walter L Biffl; K E West; Ernest E Moore; Ricardo J Gonzalez; R Carnaggio; Patrick J Offner; Christopher C Silliman
Neutrophil apoptosis is delayed by trauma patients' plasma via a mechanism involving proinflammatory phospholipids and protein kinase C.
Surgical infections 2001;2(4):289-93; discussion 294-5.
2000: Ricardo J Gonzalez; Ernest E Moore; Walter L Biffl; David J Ciesla; Christopher C Silliman
The lipid fraction of post-hemorrhagic shock mesenteric lymph (PHSML) inhibits neutrophil apoptosis and enhances cytotoxic potential.
Shock (Augusta, Ga.) 2000;14(3):404-8.
2000: David J Ciesla; Ernest E Moore; Ricardo J Gonzalez; Walter L Biffl; Christopher C Silliman
Hypertonic saline inhibits neutrophil (PMN) priming via attenuation of p38 MAPK signaling.
Shock (Augusta, Ga.) 2000;14(3):265-9; discussion 269-70.
2000: Julie Zimbelman; Christopher C Silliman; Daniel R Ambruso
Transfusion-related acute lung injury and granulocytes from stored packed RBCs.
Transfusion 2000;40(5):614-5.
2000: David J Ciesla; Ernest E Moore; Garret S Zallen; Walter L Biffl; Christopher C Silliman
Hypertonic saline attenuation of polymorphonuclear neutrophil cytotoxicity: timing is everything.
The Journal of trauma 2000;48(3):388-95.
2000: David A Partrick; Ernest E Moore; Patrick J Offner; Daniel R Meldrum; Douglas Y Tamura; Jeffrey L Johnson; Christopher C Silliman
Maximal human neutrophil priming for superoxide production and elastase release requires p38 mitogen-activated protein kinase activation.
Archives of surgery (Chicago, Ill. : 1960) 2000;135(2):219-25.
2000: Garret S Zallen; Ernest E Moore; Douglas Y Tamura; Jeffrey L Johnson; Walter L Biffl; Christopher C Silliman
Hypertonic saline resuscitation abrogates neutrophil priming by mesenteric lymph.
The Journal of trauma 2000;48(1):45-8.
2000: Garret S Zallen; Ernest E Moore; David J Ciesla; M Brown; Walter L Biffl; Christopher C Silliman
Stored red blood cells selectively activate human neutrophils to release IL-8 and secretory PLA2.
Shock (Augusta, Ga.) 2000;13(1):29-33.
1999: Garret S Zallen; Patrick J Offner; Ernest E Moore; J Blackwell; David J Ciesla; J Gabriel; C Denny; Christopher C Silliman
Age of transfused blood is an independent risk factor for postinjury multiple organ failure.
American journal of surgery 1999;178(6):570-2.
1999: Jeffrey L Johnson; Ernest E Moore; David A Partrick; Douglas Y Tamura; Garret S Zallen; David J Elzi; Christopher C Silliman; D A Patrick
Extracellular signal-related kinase 1/2 and p38 mitogen-activated protein kinase pathways serve opposite roles in neutrophil cytotoxicity.
Archives of surgery (Chicago, Ill. : 1960) 1999;134(10):1074-8.
1999: David A Partrick; Ernest E Moore; D A Fullerton; Carlton C Barnett; Daniel R Meldrum; Christopher C Silliman
Cardiopulmonary bypass renders patients at risk for multiple organ failure via early neutrophil priming and late neutrophil disability.
The Journal of surgical research 1999;86(1):42-9.
1999: Walter L Biffl; Ernest E Moore; Garret S Zallen; Jeffrey L Johnson; J Gabriel; Patrick J Offner; Christopher C Silliman
Neutrophils are primed for cytotoxicity and resist apoptosis in injured patients at risk for multiple organ failure.
Surgery 1999;126(2):198-202.
1999: Christopher C Silliman
Transfusion-related acute lung injury.
Transfusion medicine reviews 1999;13(3):177-86.
1999: Garret S Zallen; Ernest E Moore; Jeffrey L Johnson; Douglas Y Tamura; David J Ciesla; Christopher C Silliman
Posthemorrhagic shock mesenteric lymph primes circulating neutrophils and provokes lung injury.
The Journal of surgical research 1999;83(2):83-8.
1999: Jeffrey L Johnson; Ernest E Moore; Andrew A Hiester; Douglas Y Tamura; Garret S Zallen; Christopher C Silliman
Disparities in the respiratory burst between human and rat neutrophils.
Journal of leukocyte biology 1999;65(2):211-6.
1999: Garret S Zallen; Ernest E Moore; Jeffrey L Johnson; Douglas Y Tamura; B Shames; Walter L Biffl; Christopher C Silliman
Postinjury suppression of human neutrophil cytokine production results from the stabilization of inhibitory kappaB.
Shock (Augusta, Ga.) 1999;11(2):77-81.
1999: Garret S Zallen; Ernest E Moore; Jeffrey L Johnson; Douglas Y Tamura; Junichi Aiboshi; Walter L Biffl; Christopher C Silliman
Circulating postinjury neutrophils are primed for the release of proinflammatory cytokines.
The Journal of trauma 1999;46(1):42-8.
1998: Patrick J Leavey; K S Sellins; Gail Thurman; David J Elzi; Andrew A Hiester; Christopher C Silliman; Gary O Zerbe; J J Cohen; Daniel R Ambruso
In vivo treatment with granulocyte colony-stimulating factor results in divergent effects on neutrophil functions measured in vitro.
Blood 1998;92(11):4366-74.
1998: Garret S Zallen; Ernest E Moore; Jeffrey L Johnson; Douglas Y Tamura; M Barkin; Hannes Stockinger; Christopher C Silliman
New mechanisms by which secretory phospholipase A2 stimulates neutrophils to provoke the release of cytotoxic agents.
Archives of surgery (Chicago, Ill. : 1960) 1998;133(11):1229-33.
1998: J P Maloney; Christopher C Silliman; Daniel R Ambruso; Jian Wang; Rubin M Tuder; N F Voelkel
In vitro release of vascular endothelial growth factor during platelet aggregation.
The American journal of physiology 1998;275(3 Pt 2):H1054-61.
1998: Douglas Y Tamura; Ernest E Moore; Jeffrey L Johnson; Garret S Zallen; Junichi Aiboshi; Christopher C Silliman
p38 mitogen-activated protein kinase inhibition attenuates intercellular adhesion molecule-1 up-regulation on human pulmonary microvascular endothelial cells.
Surgery 1998;124(2):403-7; discussion 408.
1998: Douglas Y Tamura; Ernest E Moore; David A Partrick; Jeffrey L Johnson; Garret S Zallen; Christopher C Silliman
Primed neutrophils require phosphatidic acid for maximal receptor-activated elastase release.
The Journal of surgical research 1998;77(1):71-4.
1998: Carlton C Barnett; Ernest E Moore; Gary W Mierau; David A Partrick; Walter L Biffl; David J Elzi; Christopher C Silliman
ICAM-1-CD18 interaction mediates neutrophil cytotoxicity through protease release.
The American journal of physiology 1998;274(6 Pt 1):C1634-44.
1998: Jeffrey L Johnson; Ernest E Moore; Douglas Y Tamura; Garret S Zallen; Walter L Biffl; Christopher C Silliman
Interleukin-6 augments neutrophil cytotoxic potential via selective enhancement of elastase release.
The Journal of surgical research 1998;76(1):91-4.
1998: L A Gago; Ernest E Moore; David A Partrick; Angela Sauaia; C M Davis; T R Toal; Christopher C Silliman
Secretory phospholipase A2 cleavage of intravasated bone marrow primes human neutrophils.
The Journal of trauma 1998;44(4):660-4.
1998: David A Partrick; Ernest E Moore; Patrick J Offner; Jeffrey L Johnson; Douglas Y Tamura; Christopher C Silliman
Hypertonic saline activates lipid-primed human neutrophils for enhanced elastase release.
The Journal of trauma 1998;44(4):592-7; discussion 598.
1998: Christopher C Silliman; Norbert F Voelkel; Jenny D Allard; David J Elzi; Rubin M Tuder; Jeffrey L Johnson; Daniel R Ambruso
Plasma and lipids from stored packed red blood cells cause acute lung injury in an animal model.
The Journal of clinical investigation 1998;101(7):1458-67.
1998: Douglas Y Tamura; Ernest E Moore; David A Partrick; Jeffrey L Johnson; Patrick J Offner; Christopher C Silliman
Prostaglandin E1 attenuates cytotoxic mechanisms of primed neutrophils.
Shock (Augusta, Ga.) 1998;9(3):171-6.
1998: Douglas Y Tamura; Ernest E Moore; David A Partrick; Jeffrey L Johnson; Patrick J Offner; Ronald J Harbeck; Christopher C Silliman
Clinically relevant concentrations of ethanol attenuate primed neutrophil bactericidal activity.
The Journal of trauma 1998;44(2):320-4.
1997: David J Elzi; Andrew A Hiester; Christopher C Silliman
Receptor-mediated calcium entry is required for maximal effects of platelet activating factor primed responses in human neutrophils.
Biochemical and biophysical research communications 1997;240(3):763-5.
1997: David A Partrick; Ernest E Moore; Frederick A Moore; Carlton C Barnett; Christopher C Silliman
Lipid mediators up-regulate CD11b and prime for concordant superoxide and elastase release in human neutrophils.
The Journal of trauma 1997;43(2):297-302; discussion 302-3.
1997: David A Partrick; Ernest E Moore; Patrick J Offner; Carlton C Barnett; M Barkin; Christopher C Silliman
Nitric oxide attenuates platelet-activating factor priming for elastase release in human neutrophils via a cyclic guanosine monophosphate-dependent pathway.
Surgery 1997;122(2):196-202; discussion 202-3.
1997: Carlton C Barnett; E E Moore; David A Partrick; Christopher C Silliman
Beta-adrenergic stimulation down-regulates neutrophil priming for superoxide generation, but not elastase release.
The Journal of surgical research 1997;70(2):166-70.
1997: Christopher C Silliman; Andrew J Paterson; W O Dickey; D F Stroneck; Mark A Popovsky; S A Caldwell; Daniel R Ambruso
The association of biologically active lipids with the development of transfusion-related acute lung injury: a retrospective study.
Transfusion 1997;37(7):719-26.
1996: A J Botha; Frederick A Moore; Ernest E Moore; V M Peterson; Christopher C Silliman; A W Goode
Sequential systemic platelet-activating factor and interleukin 8 primes neutrophils in patients with trauma at risk of multiple organ failure.
The British journal of surgery 1996;83(10):1407-12.
1996: David A Partrick; Frederick A Moore; Ernest E Moore; Carlton C Barnett; Christopher C Silliman
Neutrophil priming and activation in the pathogenesis of postinjury multiple organ failure.
New horizons (Baltimore, Md.) 1996;4(2):194-210.
1996: Walter L Biffl; Ernest E Moore; Frederick A Moore; Carlton C Barnett; Christopher C Silliman; V M Peterson
Interleukin-6 stimulates neutrophil production of platelet-activating factor.
Journal of leukocyte biology 1996;59(4):569-74.
1996: Christopher C Silliman; W O Dickey; A J Paterson; Gail Thurman; Keith L Clay; C A Johnson; Daniel R Ambruso
Analysis of the priming activity of lipids generated during routine storage of platelet concentrates.
Transfusion 1996;36(2):133-9.
1995: Christopher C Silliman; N A Cusack; N J Swanson; S Ghaffarifar; Daniel R Ambruso
Platelets and neutrophils from healthy term neonates exhibit increased levels of immunoglobulins.
Pediatric research 1995;38(6):993-7.
1994: Christopher C Silliman; Keith L Clay; Gail Thurman; C A Johnson; Daniel R Ambruso
Partial characterization of lipids that develop during the routine storage of blood and prime the neutrophil NADPH oxidase.
The Journal of laboratory and clinical medicine 1994;124(5):684-94.
1994: Christopher C Silliman; GM Haase; John D Strain; D W Luckey; M A Blake; S A Caldwell; H L Wilson; Lorrie F Odom; J L Ater; B S Greffe
Indications for surgical intervention for gastrointestinal emergencies in children receiving chemotherapy.
Cancer 1994;74(1):203-16.
1993: Christopher C Silliman; D Tedder; J W Ogle; J Simon; Bette K Kleinschmidt-DeMasters; Marilyn J Manco-Johnson; Myron J Levin
Unsuspected varicella-zoster virus encephalitis in a child with acquired immunodeficiency syndrome.
The Journal of pediatrics 1993;123(3):418-22.
1993: Christopher C Silliman; G W Mierau; John D Strain; Y White; L McNeely; H Wilson; Loris McGavran; J W Cullen
Peripheral neuroepithelioma of the soft tissues. A retrospective analysis of fifteen pediatric patients.
The American journal of pediatric hematology/oncology 1993;15(3):299-305.
1993: Christopher C Silliman; V M Peterson; D L Mellman; D J Dixon; K Michael Hambidge; P A Lane
Iron chelation by deferoxamine in sickle cell patients with severe transfusion-induced hemosiderosis: a randomized, double-blind study of the dose-response relationship.
The Journal of laboratory and clinical medicine 1993;122(1):48-54.
1993: Christopher C Silliman; C A Johnson; Keith L Clay; Gail Thurman; Daniel R Ambruso
Compounds biologically similar to platelet activating factor are present in stored blood components.
Lipids 1993;28(5):415-8.
1992: Christopher C Silliman; D W Lawellin; Jacob Lohr; B M Rodgers; L G Donowitz
Paecilomyces lilacinus infection in a child with chronic granulomatous disease.
The Journal of infection 1992;24(2):191-5.
1992: Christopher C Silliman; Gail Thurman; Daniel R Ambruso
Stored blood components contain agents that prime the neutrophil NADPH oxidase through the platelet-activating-factor receptor.
Vox sanguinis 1992;63(2):133-6.
1991: Christopher C Silliman; D M Ford; P A Lane
Hemolytic uremic syndrome complicated by vitamin K deficiency.
The American journal of pediatric hematology/oncology 1991;13(2):176-8.