Alex Bobik

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Shaw James A; Bobik Alex; Murphy Andrew; Kanellakis Peter; Blombery Peter; Mukhamedova Nigora; Woollard Kevin; Lyon Stuart; Sviridov Dmitri; Dart Anthony M
Infusion of reconstituted high-density lipoprotein leads to acute changes in human atherosclerotic plaque.
Bobik Alex
Apolipoprotein CIII and atherosclerosis: beyond effects on lipid metabolism.
Malabanan Kristine P; Kanellakis Peter; Bobik Alexander; Khachigian Levon M
Activation transcription factor-4 induced by fibroblast growth factor-2 regulates vascular endothelial growth factor-A transcription in vascular smooth muscle cells and mediates intimal thickening in rat arteries following balloon injury.

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2008: Shaw James A; Bobik Alex; Murphy Andrew; Kanellakis Peter; Blombery Peter; Mukhamedova Nigora; Woollard Kevin; Lyon Stuart; Sviridov Dmitri; Dart Anthony M
Infusion of reconstituted high-density lipoprotein leads to acute changes in human atherosclerotic plaque.
Circulation research 2008;103(10):1084-91.
2008: Bobik Alex
Apolipoprotein CIII and atherosclerosis: beyond effects on lipid metabolism.
Circulation 2008;118(7):702-4.
2008: Malabanan Kristine P; Kanellakis Peter; Bobik Alexander; Khachigian Levon M
Activation transcription factor-4 induced by fibroblast growth factor-2 regulates vascular endothelial growth factor-A transcription in vascular smooth muscle cells and mediates intimal thickening in rat arteries following balloon injury.
Circulation research 2008;103(4):378-87.
2007: Santiago Fernando S; Ishii Hideto; Shafi Shahida; Khurana Rohit; Kanellakis Peter; Bhindi Ravinay; Ramirez Manfred J; Bobik Alexander; Martin John F; Chesterman Colin N; Zachary Ian C; Khachigian Levon M
Yin Yang-1 inhibits vascular smooth muscle cell growth and intimal thickening by repressing p21WAF1/Cip1 transcription and p21WAF1/Cip1-Cdk4-cyclin D1 assembly.
Circulation research 2007;101(2):146-55.
2007: Khan Razi; Agrotis Alex; Bobik Alex
Understanding the role of transforming growth factor-beta1 in intimal thickening after vascular injury.
Cardiovascular research 2007;74(2):223-34.
2006: Raj Tina; Kanellakis Peter; Pomilio Giovanna; Jennings Garry; Bobik Alex; Agrotis Alex
Inhibition of fibroblast growth factor receptor signaling attenuates atherosclerosis in apolipoprotein E-deficient mice.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(8):1845-51.
2006: Bobik Alex
Transforming growth factor-betas and vascular disorders.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(8):1712-20.
2006: Kanellakis Peter; Slater Nicholas J; Du Xiao-Jun; Bobik Alex; Curtis David J
Granulocyte colony-stimulating factor and stem cell factor improve endogenous repair after myocardial infarction.
Cardiovascular research 2006;70(1):117-25.
2006: Kalinina N I; Bobik A; Tkachuk V A
[Participation of the DNA-binding cytokine amphoterine in triggering the processes of tissue reparation]
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk 2006;92(1):39-48.
2006: Menshikov Mikhail; Torosyan Narine; Elizarova Eugenia; Plakida Karina; Vorotnikov Alexander; Parfyonova Yelena; Stepanova Victoria; Bobik Alex; Berk Bradford; Tkachuk Vsevolod
Urokinase induces matrix metalloproteinase-9/gelatinase B expression in THP-1 monocytes via ERK1/2 and cytosolic phospholipase A2 activation and eicosanoid production.
Journal of vascular research 2006;43(5):482-90.
2006: Plekhanova Olga S; Stepanova Victoria V; Ratner Elizaveta I; Bobik Alex; Tkachuk Vsevolod A; Parfyonova Yelena V
Urokinase plasminogen activator in injured adventitia increases the number of myofibroblasts and augments early proliferation.
Journal of vascular research 2006;43(5):437-46.
2005: Agrotis Alex; Kalinina Natalia; Bobik Alex
Transforming growth factor-beta, cell signaling and cardiovascular disorders.
Current vascular pharmacology 2005;3(1):55-61.
2004: Kalinina N; Agrotis A; Antropova Y; DiVitto G; Kanellakis P; Kostolias G; Ilyinskaya O; Tararak E; Bobik A
Increased expression of the DNA-binding cytokine HMGB1 in human atherosclerotic lesions: role of activated macrophages and cytokines.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(12):2320-5.
2004: Kalinina N I; Antropova Iu A; Agrotis A; il'inskaia O P; Tararak é M; Bobik A
[Expression, regulation, and pathophysiological role of NAD(P)H oxidases in atherogenesis]
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk 2004;90(10):1215-21.
2004: Agrotis Alex; Kanellakis Peter; Kostolias Gina; Di Vitto Giovanna; Wei Chen; Hannan Ross; Jennings Garry; Bobik Alex
Proliferation of neointimal smooth muscle cells after arterial injury. Dependence on interactions between fibroblast growth factor receptor-2 and fibroblast growth factor-9.
The Journal of biological chemistry 2004;279(40):42221-9.
2004: Kanellakis Peter; Nestel Paul; Bobik Alex
Angioplasty-induced superoxide anions and neointimal hyperplasia in the rabbit carotid artery: suppression by the isoflavone trans-tetrahydrodaidzein.
Atherosclerosis 2004;176(1):63-72.
2004: Taylor Andrew J; Bobik Alex; Richards Mark; Kaye David; Raines Geoffrey; Gould Paul; Jennings Garry
Myocardial endothelin-1 release and indices of inflammation during angioplasty for acute myocardial infarction and stable coronary artery disease.
American heart journal 2004;148(2):e10.
2004: Kalinina Natalia; Agrotis Alex; Antropova Yulia; Ilyinskaya Olga; Smirnov Vladimir; Tararak Eduard; Bobik Alex
Smad expression in human atherosclerotic lesions: evidence for impaired TGF-beta/Smad signaling in smooth muscle cells of fibrofatty lesions.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(8):1391-6.
2004: Parfyonova Yelena; Plekhanova Olga; Solomatina Marina; Naumov Vladimir; Bobik Alex; Berk Bradford; Tkachuk Vsevolod
Contrasting effects of urokinase and tissue-type plasminogen activators on neointima formation and vessel remodelling after arterial injury.
Journal of vascular research 2004;41(3):268-76.
2004: Taylor Andrew J; Bobik Alex; Berndt Michael C; Kannelakis Peter; Jennings Garry
Serotonin blockade protects against early microvascular constriction following atherosclerotic plaque rupture.
European journal of pharmacology 2004;486(1):85-9.
2003: Bobik Alex; Tkachuk Vselovod
Metalloproteinases and plasminogen activators in vessel remodeling.
Current hypertension reports 2003;5(6):466-72.
2003: Il'inskaia O P; Kudriashova E Iu; Antropova Iu G; Kalinina N I; Solomatina M A; Bobik A; Tararak E M
[The origin of neointimal cells in the rat carotid artery after balloon angioplasty]
Tsitologiia 2003;45(7):678-89.
2002: Kalinina Natalia; Agrotis Alex; Tararak Eduard; Antropova Yulia; Kanellakis Peter; Ilyinskaya Olga; Quinn Mark T; Smirnov Vladimir; Bobik Alex
Cytochrome b558-dependent NAD(P)H oxidase-phox units in smooth muscle and macrophages of atherosclerotic lesions.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(12):2037-43.
2002: Menshikov Mikhail; Elizarova Eugenia; Plakida Karina; Timofeeva Angelika; Khaspekov Georgy; Beabealashvilli Robert; Bobik Alex; Tkachuk Vsevolod
Urokinase upregulates matrix metalloproteinase-9 expression in THP-1 monocytes via gene transcription and protein synthesis.
The Biochemical journal 2002;367(Pt 3):833-9.
2002: Ward Michael R; Agrotis Alex; Kanellakis Peter; Hall John; Jennings Garry; Bobik Alex
Tranilast prevents activation of transforming growth factor-beta system, leukocyte accumulation, and neointimal growth in porcine coronary arteries after stenting.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(6):940-8.
2002: Taylor Andrew J; Bobik Alex; Berndt Michael C; Ramsay Debra; Jennings Garry
Experimental rupture of atherosclerotic lesions increases distal vascular resistance: a limiting factor to the success of infarct angioplasty.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(1):153-60.
2001: Bobik A; Kalinina N
Tumor necrosis factor receptor and ligand superfamily family members TNFRSF14 and LIGHT: new players in human atherogenesis.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(12):1873-5.
2001: Plekhanova O; Parfyonova Y; Bibilashvily R; Domogatskii S; Stepanova V; Gulba D C; Agrotis A; Bobik A; Tkachuk V
Urokinase plasminogen activator augments cell proliferation and neointima formation in injured arteries via proteolytic mechanisms.
Atherosclerosis 2001;159(2):297-306.
2001: Sudhir K; Hashimura K; Bobik A; Dilley R J; Jennings G L; Little P J
Mechanical strain stimulates a mitogenic response in coronary vascular smooth muscle cells via release of basic fibroblast growth factor.
American journal of hypertension 2001;14(11 Pt 1):1128-34.
2001: Ward M R; Kanellakis P; Ramsey D; Funder J; Bobik A
Eplerenone suppresses constrictive remodeling and collagen accumulation after angioplasty in porcine coronary arteries.
Circulation 2001;104(4):467-72.
2001: Kalinina N I; Ilyinskaya O P; Bobik A; Tararak E M
Effects of transforming growth factor-beta(1)on proliferation of smooth muscle cells in human aortic intima and human promonocytic leukemia THP-1 cells.
Bulletin of experimental biology and medicine 2001;131(2):162-4.
2001: Ward M R; Tsao P S; Agrotis A; Dilley R J; Jennings G L; Bobik A
Low blood flow after angioplasty augments mechanisms of restenosis: inward vessel remodeling, cell migration, and activity of genes regulating migration.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(2):208-13.
2000: Plekhanova O S; Parfyonova Y V; Bibilashvily R Sh; Stepanova V V; Erne P; Bobik A; Tkachuk V A
Urokinase plasminogen activator enhances neointima growth and reduces lumen size in injured carotid arteries.
Journal of hypertension 2000;18(8):1065-9.
2000: Ward M R; Kanellakis P; Ramsey D; Jennings G L; Bobik A
Response to balloon injury is vascular bed specific: a consequence of de novo vessel structure?
Atherosclerosis 2000;151(2):407-14.
2000: Ueno H; Kanellakis P; Agrotis A; Bobik A
Blood flow regulates the development of vascular hypertrophy, smooth muscle cell proliferation, and endothelial cell nitric oxide synthase in hypertension.
Hypertension 2000;36(1):89-96.
2000: Agrotis A; Condron M; Bobik A
Alternative splicing within the TGF-beta type I receptor gene (ALK-5) generates two major functional isoforms in vascular smooth muscle cells.
FEBS letters 2000;467(1):128-32.
1999: Neylon C B; Lang R J; Fu Y; Bobik A; Reinhart P H
Molecular cloning and characterization of the intermediate-conductance Ca(2+)-activated K(+) channel in vascular smooth muscle: relationship between K(Ca) channel diversity and smooth muscle cell function.
Circulation research 1999;85(9):e33-43.
1999: Nikashin A B; Neylon K B; Bobik A; Tkachuk V A
[Regulation of inositol-1,4,5-triphosphate receptor by G(i)-protein]
Rossiiskii fiziologicheskii zhurnal imeni I.M. Sechenova / Rossiiskaia akademiia nauk 1999;85(8):1011-21.
1999: Khachigian L M; Santiago F S; Rafty L A; Chan O L; Delbridge G J; Bobik A; Collins T; Johnson A C
GC factor 2 represses platelet-derived growth factor A-chain gene transcription and is itself induced by arterial injury.
Circulation research 1999;84(11):1258-67.
1999: Bobik A; Agrotis A; Kanellakis P; Dilley R; Krushinsky A; Smirnov V; Tararak E; Condron M; Kostolias G
Distinct patterns of transforming growth factor-beta isoform and receptor expression in human atherosclerotic lesions. Colocalization implicates TGF-beta in fibrofatty lesion development.
Circulation 1999;99(22):2883-91.
1998: Bobik A; Dilley R; Kanellakis P
Sympatho-adrenal mechanisms regulating cardiovascular hypertrophy in primary hypertension: a role for rilmenidine?
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1998;16(3):S51-4.
1998: Neylon C B; Nickashin A; Tkachuk V A; Bobik A
Heterotrimeric Gi protein is associated with the inositol 1,4,5-trisphosphate receptor complex and modulates calcium flux.
Cell calcium 1998;23(5):281-9.
1998: Ward M R; Sasahara T; Agrotis A; Dilley R J; Jennings G L; Bobik A
Inhibitory effects of tranilast on expression of transforming growth factor-beta isoforms and receptors in injured arteries.
Atherosclerosis 1998;137(2):267-75.
1998: Bray P; Agrotis A; Bobik A
Transforming growth factor-beta and receptor tyrosine kinase-activating growth factors negatively regulate collagen genes in smooth muscle of hypertensive rats.
Hypertension 1998;31(4):986-94.
1998: Ward M R; Agrotis A; Jennings G; Bobik A
Vascular types I and II transforming growth factor-beta receptor expression: differential dependency on tyrosine kinases during induction by TGF-beta.
FEBS letters 1998;422(2):197-200.
1997: Ward M R; Agrotis A; Kanellakis P; Dilley R; Jennings G; Bobik A
Inhibition of protein tyrosine kinases attenuates increases in expression of transforming growth factor-beta isoforms and their receptors following arterial injury.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(11):2461-70.
1997: Black M J; Kanellakis P; Bobik A
Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats.
Journal of hypertension 1997;15(9):945-54.
1997: Stepanova V; Bobik A; Bibilashvily R; Belogurov A; Rybalkin I; Domogatsky S; Little P J; Goncharova E; Tkachuk V
Urokinase plasminogen activator induces smooth muscle cell migration: key role of growth factor-like domain.
FEBS letters 1997;414(2):471-4.
1997: Wong J; Rauhöft C; Dilley R J; Agrotis A; Jennings G L; Bobik A
Angiotensin-converting enzyme inhibition abolishes medial smooth muscle PDGF-AB biosynthesis and attenuates cell proliferation in injured carotid arteries: relationships to neointima formation.
Circulation 1997;96(5):1631-40.
1997: Du X J; Bobik A; Little P J; Esler M D; Dart A M
Role of Ca2+ in metabolic inhibition-induced norepinephrine release in rat brain synaptosomes.
Circulation research 1997;80(2):179-88.
1997: Black M J; Niklaus A; Bertram J F; Dilley R; Bobik A
Vascular growth responses in SHR and WKY during development of renal (1K1C) hypertension.
American journal of hypertension 1997;10(1):43-50.
1996: Saltis J; Bobik A
Regulation by protein kinase C of transforming growth factor-beta 1 action on the proliferation of vascular smooth muscle cells from spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology 1996;23(6-7):573-5.
1996: Agrotis A; Bobik A
Vascular remodelling and molecular biology: new concepts and therapeutic possibilities.
Clinical and experimental pharmacology & physiology 1996;23(5):363-8.
1996: Saltis J; Agrotis A; Bobik A
Regulation and interactions of transforming growth factor-beta with cardiovascular cells: implications for development and disease.
Clinical and experimental pharmacology & physiology 1996;23(3):193-200.
1996: Agrotis A; Samuel M; Prapas G; Bobik A
Vascular smooth muscle cells express multiple type I receptors for TGF-beta, activin, and bone morphogenetic proteins.
Biochemical and biophysical research communications 1996;219(2):613-8.
1995: Saltis J; Bobik A
Developmental regulation of transforming growth factor-beta 1 responses and vascular smooth muscle growth in spontaneously hypertensive rats.
Journal of hypertension 1995;13(12 Pt 1):1441-8.
1995: Saltis J; Thomas A C; Agrotis A; Campbell J H; Campbell G R; Bobik A
Expression of growth factor receptors in arterial smooth muscle cells. Dependency on cell phenotype and serum factors.
Atherosclerosis 1995;118(1):77-87.
1995: Neylon C B; Richards S M; Larsen M A; Agrotis A; Bobik A
Multiple types of ryanodine receptor/Ca2+ release channels are expressed in vascular smooth muscle.
Biochemical and biophysical research communications 1995;215(3):814-21.
1995: Korner P I; Bobik A
Cardiovascular development after enalapril in spontaneously hypertensive and Wistar-Kyoto rats.
Hypertension 1995;25(4 Pt 1):610-9.
1995: Little P J; Neylon C B; Farrelly C A; Weissberg P L; Cragoe E J; Bobik A
Intracellular pH in vascular smooth muscle: regulation by sodium-hydrogen exchange and multiple sodium dependent HCO3- mechanisms.
Cardiovascular research 1995;29(2):239-46.
1995: Agrotis A; Saltis J; Dilley R; Bray P; Bobik A
Transforming growth factor-beta 1 and the development of vascular hypertrophy in hypertension.
Blood pressure. Supplement 1995;2():43-8.
1994: Neylon C B; Bryant S M; Little P J; Bobik A
Transforming growth factor-beta 1 regulates the expression of ryanodine-sensitive Ca2+ oscillations in cardiac myocytes.
Biochemical and biophysical research communications 1994;204(2):678-84.
1994: Neylon C B; Avdonin P V; Dilley R J; Larsen M A; Tkachuk V A; Bobik A
Different electrical responses to vasoactive agonists in morphologically distinct smooth muscle cell types.
Circulation research 1994;75(4):733-41.
1994: Dilley R J; Kanellakis P; Oddie C J; Bobik A
Vascular hypertrophy in renal hypertensive spontaneously hypertensive rats.
Hypertension 1994;24(1):8-15.
1994: Agrotis A; Saltis J; Bobik A
Transforming growth factor-beta 1 gene activation and growth of smooth muscle from hypertensive rats.
Hypertension 1994;23(5):593-9.
1994: Saltis J; Agrotis A; Kanellakis P; Bobik A
Developmentally regulated transforming growth factor-beta 1 action on vascular smooth muscle growth in the SHR.
Clinical and experimental pharmacology & physiology 1994;21(2):149-52.
1994: Agrotis A; Saltis J; Bobik A
Effect of transforming growth factor-beta 1 on platelet-derived growth factor receptor binding and gene expression in vascular smooth muscle cells from SHR and WKY rats.
Clinical and experimental pharmacology & physiology 1994;21(2):145-8.
1994: Neylon C B; Avdonin P V; Larsen M A; Bobik A
Rat aortic smooth muscle cells expressing charybdotoxin-sensitive potassium channels exhibit enhanced proliferative responses.
Clinical and experimental pharmacology & physiology 1994;21(2):117-20.
1993: Black M J; Dilley R J; Bobik A
Renin-dependent hypertension induces smooth muscle polyploidy in large and small vessels.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1993;11(5):S118-9.
1993: Bobik A
Pharmacological considerations in digoxin therapy.
The Medical journal of Australia 1993;159(10):678-81.
1993: Korner P; Bobik A; Oddie C; Friberg P
Sympathoadrenal system is critical for structural changes in genetic hypertension.
Hypertension 1993;22(2):243-52.
1993: Oddie C J; Dilley R J; Kanellakis P; Bobik A
Chronic angiotensin II type 1 receptor antagonism in genetic hypertension: effects on vascular structure and reactivity.
Journal of hypertension 1993;11(7):717-24.
1993: Saltis J; Agrotis A; Bobik A
Differences in growth characteristics of vascular smooth muscle from spontaneously hypertensive and Wistar-Kyoto rats are growth factor dependent.
Journal of hypertension 1993;11(6):629-37.
1993: Agrotis A; Bray P J; Saltis J; Bobik A
Vascular smooth muscle cell proliferation in SHR and WKY rats: evidence for specific differences in growth inhibitory regulatory mechanisms.
Clinical and experimental pharmacology & physiology 1993;20(5):327-30.
1993: Saltis J; Agrotis A; Bobik A
Age-dependent alterations in vascular smooth muscle cell responsiveness to platelet-derived growth factor in genetic hypertension.
Clinical and experimental pharmacology & physiology 1993;20(5):324-6.
1993: Agrotis A; Little P J; Saltis J; Bobik A
Dihydropyridine Ca2+ channel antagonists inhibit the salvage pathway for DNA synthesis in human vascular smooth muscle cells.
European journal of pharmacology 1993;244(3):269-75.
1992: Saltis J; Agrotis A; Bobik A
TGF-beta 1 potentiates growth factor-stimulated proliferation of vascular smooth muscle cells in genetic hypertension.
The American journal of physiology 1992;263(2 Pt 1):C420-8.
1992: Saltis J; Bobik A
Vascular smooth muscle growth in genetic hypertension: evidence for multiple abnormalities in growth regulatory pathways.
Journal of hypertension 1992;10(7):635-43.
1992: Saltis J; Agrotis A; Bobik A
Differential regulation by transforming growth factor-beta 1 of platelet-derived growth factor-stimulated proliferation of vascular smooth muscle cells from SHR and WKY rats.
Clinical and experimental pharmacology & physiology 1992;19(5):396-9.
1992: Oddie C J; Dilley R J; Bobik A
Long-term angiotensin II antagonism in spontaneously hypertensive rats: effects on blood pressure and cardiovascular amplifiers.
Clinical and experimental pharmacology & physiology 1992;19(5):392-5.
1992: Neylon C B; Nickashin A; Little P J; Tkachuk V A; Bobik A
Thrombin-induced Ca2+ mobilization in vascular smooth muscle utilizes a slowly ribosylating pertussis toxin-sensitive G protein. Evidence for the involvement of a G protein in inositol trisphosphate-dependent Ca2+ release.
The Journal of biological chemistry 1992;267(11):7295-302.
1992: Little P J; Neylon C B; Tkachuk V A; Bobik A
Endothelin-1 and endothelin-3 stimulate calcium mobilization by different mechanisms in vascular smooth muscle.
Biochemical and biophysical research communications 1992;183(2):694-700.
1991: Head G A; Minami N; Adams M A; Bobik A
Development of cardiac hypertrophy and its relationship to the cardiac baroreflex deficit in hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S80-1.
1991: Korner P I; Angus J A; Bobik A; Jennings G L
Amplifier function of resistance vessels and the left ventricle in hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(2):S31-40; discussion S40-1.
1991: Saltis J; Agrotis A; Bobik A
Transforming growth factor-beta 1 enhances the proliferative effects of epidermal growth factor on vascular smooth muscle from the spontaneously hypertensive rat.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1991;9(6):S184-5.
1991: Saltis J; Little P; Bobik A
Multiple growth abnormalities in vascular smooth muscle from spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology 1991;18(5):319-22.
1991: Bobik A; Grooms A; Little P J; Cragoe E J; Grinpukel S
Ethylisopropylamiloride-sensitive pH control mechanisms modulate vascular smooth muscle cell growth.
The American journal of physiology 1991;260(3 Pt 1):C581-8.
1991: Bobik A; Little P J; Neylon C B
Ionic mechanisms regulating sodium entry into vascular smooth muscle.
Clinical and experimental pharmacology & physiology 1991;18(2):117-20.
1991: Korner P I; Bobik A; Jennings G L; Angus J A; Anderson W P
Significance of cardiovascular hypertrophy in the development and maintenance of hypertension.
Journal of cardiovascular pharmacology 1991;17 Suppl 2():S25-32.
1990: Neylon C B; Little P J; Cragoe E J; Bobik A
Intracellular pH in human arterial smooth muscle. Regulation by Na+/H+ exchange and a novel 5-(N-ethyl-N-isopropyl)amiloride-sensitive Na(+)- and HCO3(-)-dependent mechanism.
Circulation research 1990;67(4):814-25.
1990: Adams M A; Bobik A; Korner P I
Enalapril can prevent vascular amplifier development in spontaneously hypertensive rats.
Hypertension 1990;16(3):252-60.
1990: Bobik A; Neylon C B; Little P J; Cragoe E J; Weissberg P L
Sodium-dependent, ethylisopropylamiloride-sensitive mechanisms regulate intracellular pH in human vascular smooth muscle.
Clinical and experimental pharmacology & physiology 1990;17(4):297-301.
1990: Bobik A; Grooms A; Millar J A; Mitchell A; Grinpukel S
Growth factor activity of endothelin on vascular smooth muscle.
The American journal of physiology 1990;258(3 Pt 1):C408-15.
1990: Bobik A; Grinpukel S; Little P J; Grooms A; Jackman G
Angiotensin II and noradrenaline increase PDGF-BB receptors and potentiate PDGF-BB stimulated DNA synthesis in vascular smooth muscle.
Biochemical and biophysical research communications 1990;166(2):580-8.
1989: Korner P I; Bobik A; Angus J A; Adams M A; Friberg P
Resistance control in hypertension.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1989;7(4):S125-34; discussion S135.
1989: Adams M A; Bobik A; Korner P I
Differential development of vascular and cardiac hypertrophy in genetic hypertension. Relation to sympathetic function.
Hypertension 1989;14(2):191-202.
1989: Weissberg P L; Little P J; Bobik A
Spontaneous oscillations in cytoplasmic calcium concentration in vascular smooth muscle.
The American journal of physiology 1989;256(5 Pt 1):C951-7.
1989: Weissberg P L; Little P J; Cragoe E J; Bobik A
The pH of spontaneously beating cultured rat heart cells is regulated by an ATP-calmodulin-dependent Na+/H+ antiport.
Circulation research 1989;64(4):676-85.
1989: Wolf W A; Bobik A
alpha-Methyldopa metabolism in central serotonergic nerve terminals: effects on serotonin levels, synthesis and release.
European journal of pharmacology 1989;163(1):43-53.
1988: Bobik A; Grooms A; Grinpukel S; Little P J
The effects of alterations in membrane sodium transport on rat aortic smooth muscle proliferation.
Journal of hypertension. Supplement : official journal of the International Society of Hypertension 1988;6(4):S219-21.
1988: Little P J; Weissberg P L; Cragoe E J; Bobik A
Dependence of Na+/H+ antiport activation in cultured rat aortic smooth muscle on calmodulin, calcium, and ATP. Evidence for the involvement of calmodulin-dependent kinases.
The Journal of biological chemistry 1988;263(32):16780-6.
1988: Bobik A; Oddie C; Scott P; Mill G; Korner P
Relationships between the cardiovascular effects of alpha-methyldopa and its metabolism in pontomedullary noradrenergic neurons of the rabbit.
Journal of cardiovascular pharmacology 1988;11(5):529-37.
1988: Black M J; Adams M A; Bobik A; Campbell J H; Campbell G R
Vascular smooth muscle polyploidy in the development and regression of hypertension.
Clinical and experimental pharmacology & physiology 1988;15(4):345-8.
1988: Bobik A; Weissberg P L; Little P J
Spontaneous oscillations in cytoplasmic free calcium concentration in vascular smooth muscle: a potential mechanism associated with myogenic tone.
Clinical and experimental pharmacology & physiology 1988;15(4):281-4.
1988: Scott P J; Little P J; Bobik A
Circulating digoxin-like immunoreactivity in renal hypertensive rabbits: lack of modulation by alterations in dietary sodium intake.
Journal of hypertension 1988;6(3):205-9.
1988: Korner P I; Adams M A; Jennings G L; Bobik A
Effect of antihypertensive therapy on the cardiovascular amplifiers.
Clinical and experimental pharmacology & physiology 1988;15(3):191-7.
1988: Wolf W A; Bobik A
Effects of 5,6-dihydroxytryptamine on the release, synthesis, and storage of serotonin: studies using rat brain synaptosomes.
Journal of neurochemistry 1988;50(2):534-42.
1988: Little P J; Weissberg P L; Cragoe E J; Bobik A
Mechanisms influencing sodium entry to cultured vascular smooth muscle.
Progress in biochemical pharmacology 1988;23():142-9.
1987: Anderson W P; Bobik A
Effects of five non-steroidal anti-inflammatory drugs on the renal and systemic responses to arachidonate in conscious dogs.
Clinical and experimental pharmacology & physiology 1987;14(8):649-57.
1987: Korner P I; Jennings G L; Esler M D; Anderson W P; Bobik A; Adams M; Angus J A
The cardiovascular amplifiers in human primary hypertension and their role in a strategy for detecting the underlying causes.
Canadian journal of physiology and pharmacology 1987;65(8):1730-8.
1987: Bobik A; Weissberg P L; Little P J
Regulation of sodium influx and sodium, potassium pump activity by a sodium-hydrogen antiport in rat vascular smooth muscle.
Clinical and experimental pharmacology & physiology 1987;14(3):191-5.
1987: Korner P I; Head G A; Badoer E; Bobik A; Angus J A
Role of brain amine transmitters and some neuromodulators in blood pressure, heart rate, and baroreflex control.
Journal of cardiovascular pharmacology 1987;10 Suppl 12():S26-32.
1986: Oddie C J; Jackman G P; Bobik A
Analysis of milrinone in plasma using solid-phase extraction and high-performance liquid chromatography.
Journal of chromatography 1986;374(1):209-14.
1986: Bobik A; Jennings G; Jackman G; Oddie C; Korner P
Evidence for a predominantly central hypotensive effect of alpha-methyldopa in humans.
Hypertension 1986;8(1):16-23.
1984: Bobik A; Badoer E; Oddie C; Head G; Korner P
Contribution of central and peripheral mechanisms to the antihypertensive effects of alpha-methyldopa in the rabbit.
Journal of cardiovascular pharmacology 1984;6(6):1109-14.
1984: Korner P I; Head G A; Bobik A; Badoer E; Aberdeen J A
Central and peripheral autonomic mechanisms involved in the circulatory actions of methyldopa.
Hypertension 1984;6(5 Pt 2):II63-70.
1984: Jackman G P; Oddie C J; Skews H; Bobik A
High-performance liquid chromatographic determination of plasma catecholamines during alpha-methyldopa therapy.
Journal of chromatography 1984;308():301-5.
1984: Oddie C J; Jackman G P; Bobik A
Measurement of xamoterol in plasma and urine by high-performance liquid chromatography.
Journal of chromatography 1984;308():370-5.
1983: Jennings G; Bobik A; Oddie C; Hargreaves M; Korner P
Cardioselectivity of prenalterol and isoproterenol.
Clinical pharmacology and therapeutics 1983;34(6):749-57.
1983: Oddie C J; Jackman G P; Bobik A
Analysis of bopindolol and its active metabolite 18-502 in human plasma by high-performance liquid chromatography.
Journal of chromatography 1983;273(2):469-74.
1982: Oddie C J; Jackman G P; Bobik A
Determination of prenalterol in plasma by high-performance liquid chromatography with fluorescence detection.
Journal of chromatography 1982;231(2):473-7.
1982: Jackman G; Snell J; Skews H; Bobik A
Effects of noradrenergic neuronal activity on 3,4-dihydroxyphenylethylene glycol (DHPG) levels. Quantitation by high performance liquid chromatography.
Life sciences 1982;31(9):923-9.
1981: Jennings G; Bobik A; Esler M; Korner P
Contribution of cardiovascular reflexes to differences in beta-adrenoceptor-mediated responses in essential hypertension.
Clinical science (London, England : 1979) 1981;61 Suppl 7():177s-180s.
1981: Bobik A; Jennings G; Skews H; Esler M; McLean A
Low oral bioavailability of dihydroergotamine and first-pass extraction in patients with orthostatic hypotension.
Clinical pharmacology and therapeutics 1981;30(5):673-9.
1981: Esler M; Turbott J; Schwarz R; Leonard P; Jackman G; Skews H; Bobik A; Jennings G; Korner P
Differing noradrenaline kinetics in essential hypertension and depressive illness, two diseases in which the plasma concentration of noradrenaline is sometimes elevated.
Clinical and experimental pharmacology & physiology 1981;8(5):525-30.
1981: Esler M; Jackman G; Bobik A; Leonard P; Kelleher D; Skews H; Jennings G; Korner P
Norepinephrine kinetics in essential hypertension. Defective neuronal uptake of norepinephrine in some patients.
Hypertension 1981;3(2):149-56.
1981: Esler M; Skews H; Leonard P; Jackman G; Bobik A; Korner P
Age-dependence of noradrenaline kinetics in normal subjects.
Clinical science (London, England : 1979) 1981;60(2):217-9.
1981: Esler M; Jackman G; Leonard P; Skews H; Bobik A; Korner P
Effect of norepinephrine uptake blockers on norepinephrine kinetics.
Clinical pharmacology and therapeutics 1981;29(1):12-20.
1980: Esler M; Jackman G; Leonard P; Bobik A; Skews H; Jennings G; Kelleher D; Korner P
Determination of noradrenaline uptake, spillover to plasma and plasma concentration in patients with essential hypertension.
Clinical science (London, England : 1979) 1980;59 Suppl 6():311s-313s.
1980: Esler M; Leonard P; Kelleher D; Jackman G; Bobik A; Skews H; Jennings G; Korner P
Assessment of neuronal uptake of noradrenaline in humans: defective uptake in some patients with essential hypertension.
Clinical and experimental pharmacology & physiology 1980;7(5):535-9.
1980: Jackman G P; Carson V J; Bobik A; Skews H
Simple and sensitive procedure for the assay of serotonin and catecholamines in brain by high-performance liquid chromatography using fluorescence detection.
Journal of chromatography 1980;182(3-4):277-84.
1980: Esler M; Jackman G; Kelleher D; Skews H; Jennings G; Bobik A; Korner P
Norepinephrine kinetics in patients with idiopathic autonomic insufficiency.
Circulation research 1980;46(6 Pt 2):I47-8.
1980: Esler M; Leonard P; Jackman G; Bobik A; Skews H
Study of noradrenaline uptake and spillover to plasma in normal subjects and patients with essential hypertension.
Progress in biochemical pharmacology 1980;17():75-83.

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