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Alcino Silva

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Antonella Caccamo; Manuel F López-Aranda; Andrea Magrì; David X Medina; Alcino J Silva; Elena V Wisely; Salvatore Oddo
mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.
Xiaoning Han; Lane Bekar; Sarah Betstadt; Michael Chen; Steven Goldman; Nancy Ann Oberheim; Steven Shanz; Alcino J Silva; Takahiro Takano; Fushun Wang; Su Wang; martha windrem; Qiwu Xu; Maiken Nedergaard
Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice.
Miou Zhou; Yu Zhou; Ying Zhou; Hongjun Song; Juan Song; Xiaoli Tian; Shumin Wu; J Balaji; Dan Ehninger; Lin He; Shan Huang; Eunchai Kang; Ju Young Kim; Weidong Li; Cindy Liu; Guo-Li Ming; Sherveen N Parivash; Yoshitake Sano; Alcino J Silva
mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons.

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2013: Antonella Caccamo; Manuel F López-Aranda; Andrea Magrì; David X Medina; Alcino J Silva; Elena V Wisely; Salvatore Oddo
mTOR regulates tau phosphorylation and degradation: implications for Alzheimer's disease and other tauopathies.
Aging cell 2013;12(3):370-80.
2013: Xiaoning Han; Lane Bekar; Sarah Betstadt; Michael Chen; Steven Goldman; Nancy Ann Oberheim; Steven Shanz; Alcino J Silva; Takahiro Takano; Fushun Wang; Su Wang; martha windrem; Qiwu Xu; Maiken Nedergaard
Forebrain engraftment by human glial progenitor cells enhances synaptic plasticity and learning in adult mice.
Cell stem cell 2013;12(3):342-53.
2013: Miou Zhou; Yu Zhou; Ying Zhou; Hongjun Song; Juan Song; Xiaoli Tian; Shumin Wu; J Balaji; Dan Ehninger; Lin He; Shan Huang; Eunchai Kang; Ju Young Kim; Weidong Li; Cindy Liu; Guo-Li Ming; Sherveen N Parivash; Yoshitake Sano; Alcino J Silva
mTOR Inhibition ameliorates cognitive and affective deficits caused by Disc1 knockdown in adult-born dentate granule neurons.
Neuron 2013;77(4):647-54.
2012: David H Gutmann; Luis F Parada; Alcino J Silva; Nancy Ratner
Neurofibromatosis type 1: modeling CNS dysfunction.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(41):14087-93.
2012: Maria T Acosta; Carrie E Bearden; Xavier F Castellanos; LAURA CUTTING; Ype Elgersma; Gerard Gioia; David H Gutmann; Kim Hunter-Schaedle; Yong-Seok Lee; Eric Legius; Maximillian Muenke; Kathryn North; Luis F Parada; Nancy Ratner; F Xavier Castellanos; Alcino J Silva
The Learning Disabilities Network (LeaDNet): using neurofibromatosis type 1 (NF1) as a paradigm for translational research.
American journal of medical genetics. Part A 2012;158A(9):2225-32.
2012: Amos Gdalyahu; Peyman Golshani; Robin Gruver; Pierre-Olivier Polack; Alcino J Silva; Michael S Fanselow; Elaine Tring; Joshua T Trachtenberg
Associative fear learning enhances sparse network coding in primary sensory cortex.
Neuron 2012;75(1):121-32.
2012: Amy R Halt; Nils Brose; Robert F Dallapiazza; Scott Juntti; Hai Qian; Alcino J Silva; Ivar S Stein; Sonja Wojcik; Yu Zhou; Johannes Hell
CaMKII binding to GluN2B is critical during memory consolidation.
The EMBO journal 2012;31(5):1203-16.
2012: Jeiwon Cho; Ype Elgersma; Rushi Bhatt; Alcino J Silva
α-Calcium calmodulin kinase II modulates the temporal structure of hippocampal bursting patterns.
PloS one 2012;7(2):e31649.
2011: Yong-Seok Lee; Alcino J Silva
Modeling hyperactivity: of mice and men.
Nature medicine 2011;17(5):541-2.
2011: Dan Ehninger; Alcino J Silva
Increased levels of anxiety-related behaviors in a Tsc2 dominant negative transgenic mouse model of tuberous sclerosis.
Behavior genetics 2011;41(3):357-63.
2011: Dan Ehninger; Alcino J Silva
Rapamycin for treating Tuberous sclerosis and Autism spectrum disorders.
Trends in molecular medicine 2011;17(2):78-87.
2011: Min-Jeong Kye; Yong-Seok Lee; Pierre Neveu; Mustafa Sahin; Judith A Steen; Miou Zhou; Kenneth S Kosik; Alcino J Silva
NMDA mediated contextual conditioning changes miRNA expression.
PloS one 2011;6(9):e24682.
2010: Megumi Kaneko; Claire E Cheetham; Yong-Seok Lee; Alcino J Silva; Michael P Stryker; Kevin Fox
Constitutively active H-ras accelerates multiple forms of plasticity in developing visual cortex.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(44):19026-31.
2010: Brian J Wiltgen; Miou Zhou; Ying Cai; J Balaji; Mikael Guzman Karlsson; Sherveen N Parivash; Weidong Li; Alcino J Silva
The hippocampus plays a selective role in the retrieval of detailed contextual memories.
Current biology : CB 2010;20(15):1336-44.
2010: Carrie Shilyansky; Katherine H Karlsgodt; Damian M Cummings; Kyriaki Sidiropoulou; Molly Hardt; Alex S James; Dan Ehninger; Carrie E Bearden; Panayiota Poirazi; J David Jentsch; Tyrone D Cannon; Michael S Levine; Alcino J Silva
Neurofibromin regulates corticostriatal inhibitory networks during working memory performance.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(29):13141-6.
2010: Isabelle Buard; Steven J Coultrap; Ronald K Freund; Yong-Seok Lee; Mark L Dell'Acqua; Alcino J Silva; K Ulrich Bayer
CaMKII "autonomy" is required for initiating but not for maintaining neuronal long-term information storage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(24):8214-20.
2010: Jian Feng; Yu Zhou; Susan L Campbell; Thuc Le; En Li; J David Sweatt; Alcino J Silva; Guoping Fan
Dnmt1 and Dnmt3a maintain DNA methylation and regulate synaptic function in adult forebrain neurons.
Nature neuroscience 2010;13(4):423-30.
2010: Anna Matynia; Carina Hoi Ng; Warunee Dansithong; Andy Chiang; Alcino J Silva; Sita Reddy
Muscleblind1, but not Dmpk or Six5, contributes to a complex phenotype of muscular and motivational deficits in mouse models of myotonic dystrophy.
PloS one 2010;5(3):e9857.
2010: C Shilyansky; Y S Lee; Alcino J Silva
Molecular and cellular mechanisms of learning disabilities: a focus on NF1.
Annual review of neuroscience 2010;33():221-43.
2009: Yu Zhou; Jaejoon Won; Mikael Guzman Karlsson; Miou Zhou; Thomas Rogerson; Jayaprakash Balaji; Rachael Neve; Panayiota Poirazi; Alcino J Silva
CREB regulates excitability and the allocation of memory to subsets of neurons in the amygdala.
Nature neuroscience 2009;12(11):1438-43.
2009: Alcino J Silva; Yu Zhou; Thomas Rogerson; Justin Shobe; J Balaji
Molecular and cellular approaches to memory allocation in neural circuits.
Science (New York, N.Y.) 2009;326(5951):391-5.
2009: Dan Ehninger; P J de Vries; Alcino J Silva
From mTOR to cognition: molecular and cellular mechanisms of cognitive impairments in tuberous sclerosis.
Journal of intellectual disability research : JIDR 2009;53(10):838-51.
2009: Dan Ehninger; Alcino J Silva
Genetics and neuropsychiatric disorders: treatment during adulthood.
Nature medicine 2009;15(8):849-50.
2009: Leah K Hutnick; Peyman Golshani; Masakasu Namihira; Zhigang Xue; Anna Matynia; X William Yang; Alcino J Silva; Felix E Schweizer; Guoping Fan
DNA hypomethylation restricted to the murine forebrain induces cortical degeneration and impairs postnatal neuronal maturation.
Human molecular genetics 2009;18(15):2875-88.
2009: Alcino J Silva; Dan Ehninger
Adult reversal of cognitive phenotypes in neurodevelopmental disorders.
Journal of neurodevelopmental disorders 2009;1(2):150-7.
2009: Yong-Seok Lee; Alcino J Silva
The molecular and cellular biology of enhanced cognition.
Nature reviews. Neuroscience 2009;10(2):126-40.
2009: duong huynh; Marwan Maalouf; Alcino J Silva; Felix E Schweizer; Stef pulst
Dissociated fear and spatial learning in mice with deficiency of ataxin-2.
PloS one 2009;4(7):e6235.
2008: Dan Ehninger; Weidong Li; Kevin Fox; Michael P Stryker; Alcino J Silva
Reversing neurodevelopmental disorders in adults.
Neuron 2008;60(6):950-60.
2008: Ryoichi Kimura; Alcino J Silva; MASUO OHNO
Autophosphorylation of alphaCaMKII is differentially involved in new learning and unlearning mechanisms of memory extinction.
Learning & memory (Cold Spring Harbor, N.Y.) 2008;15(11):837-43.
2008: Yijun Cui; Rui M Costa; Geoffrey G Murphy; Ype Elgersma; Yuan Zhu; David H Gutmann; Luis F Parada; Istvan Mody; Alcino J Silva
Neurofibromin regulation of ERK signaling modulates GABA release and learning.
Cell 2008;135(3):549-60.
2008: Dan Ehninger; Sangyeul Han; Carrie Shilyansky; Yu Zhou; Weidong Li; David J Kwiatkowski; Vijaya Ramesh; Alcino J Silva
Reversal of learning deficits in a Tsc2+/- mouse model of tuberous sclerosis.
Nature medicine 2008;14(8):843-8.
2008: Lianne C Krab; Arja de Goede-Bolder; Femke K Aarsen; Saskia M F Pluijm; Marlies J Bouman; Jos N van der Geest; Maarten H Lequin; Coriene E Catsman; W F M Arts; Steven A Kushner; Alcino J Silva; Chris I De Zeeuw; Henriëtte A Moll; Ype Elgersma
Effect of simvastatin on cognitive functioning in children with neurofibromatosis type 1: a randomized controlled trial.
JAMA : the journal of the American Medical Association 2008;300(3):287-94.
2008: Katherine A Rauen; Erin Hefner; Kristin Carrillo; Jill Taylor; Laure Messier; Yoko Aoki; Karen W Gripp; Yoichi Matsubara; Virginia K Proud; Peter Hammond; Judith E Allanson; Marie-Ange Delrue; Marni E Axelrad; Angela E Lin; Daniel A Doyle; Bronwyn Kerr; John C Carey; Frank McCormick; Alcino J Silva; Mark W Kieran; Aleksander Hinek; Tan T Nguyen; Lisa Schoyer
Molecular aspects, clinical aspects and possible treatment modalities for Costello syndrome: Proceedings from the 1st International Costello Syndrome Research Symposium 2007.
American journal of medical genetics. Part A 2008;146A(9):1205-17.
2008: Jaejoon Won; Alcino J Silva
Molecular and cellular mechanisms of memory allocation in neuronetworks.
Neurobiology of learning and memory 2008;89(3):285-92.
2008: Anna Matynia; Stephan Anagnostaras; Brian J Wiltgen; Maress Lacuesta; Michael S Fanselow; Alcino J Silva
A high through-put reverse genetic screen identifies two genes involved in remote memory in mice.
PloS one 2008;3(5):e2121.
2007: Yu Zhou; Eiki Takahashi; Weidong Li; Amy Halt; Brian J Wiltgen; Dan Ehninger; Guo-Dong Li; Johannes Hell; Mary B Kennedy; Alcino J Silva
Interactions between the NR2B receptor and CaMKII modulate synaptic plasticity and spatial learning.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(50):13843-53.
2007: Weidong Li; Yu Zhou; J David Jentsch; Robert A M Brown; Xiaoli Tian; Dan Ehninger; William Hennah; Leena Peltonen; Jouko Lönnqvist; Matti O Huttunen; Jaakko Kaprio; Joshua T Trachtenberg; Alcino J Silva; Tyrone D Cannon
Specific developmental disruption of disrupted-in-schizophrenia-1 function results in schizophrenia-related phenotypes in mice.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(46):18280-5.
2007: Mohammad Reza Hojjati; Geeske M van Woerden; William Tyler; peter giese; Alcino J Silva; Lucas Pozzo-Miller; Ype Elgersma
Kinase activity is not required for alphaCaMKII-dependent presynaptic plasticity at CA3-CA1 synapses.
Nature neuroscience 2007;10(9):1125-7.
2007: Alcino J Silva
The science of research: the principles underlying the discovery of cognitive and other biological mechanisms.
Journal of physiology, Paris 2007;101(4-6):203-13.
2007: Jin-Hee Han; Steven A Kushner; Adelaide P Yiu; Christy J Cole; Anna Matynia; Robert A Brown; Rachael L Neve; John Guzowski; Alcino J Silva; Sheena A Josselyn
Neuronal competition and selection during memory formation.
Science (New York, N.Y.) 2007;316(5823):457-60.
2007: Brian J Wiltgen; Alcino J Silva
Memory for context becomes less specific with time.
Learning & memory (Cold Spring Harbor, N.Y.) 2007;14(4):313-7.
2006: Geoffrey G Murphy; Vaibhavi Shah; Johannes Hell; Alcino J Silva
Investigation of age-related cognitive decline using mice as a model system: neurophysiological correlates.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006;14(12):1012-21.
2006: Geoffrey G Murphy; Nancy P Rahnama; Alcino J Silva
Investigation of age-related cognitive decline using mice as a model system: behavioral correlates.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2006;14(12):1004-11.
2006: Paul W Frankland; Hoi-Ki Ding; Eiki Takahashi; Akinobu Suzuki; Satoshi Kida; Alcino J Silva
Stability of recent and remote contextual fear memory.
Learning & memory (Cold Spring Harbor, N.Y.) 2006;13(4):451-7.
2006: MASUO OHNO; Evgeny A Sametsky; Alcino J Silva; John F Disterhoft
Differential effects of alphaCaMKII mutation on hippocampal learning and changes in intrinsic neuronal excitability.
The European journal of neuroscience 2006;23(8):2235-40.
2006: Maria T Acosta; Gerard A Gioia; Alcino J Silva
Neurofibromatosis type 1: new insights into neurocognitive issues.
Current neurology and neuroscience reports 2006;6(2):136-43.
2006: Vanja Nagy; Ozlem Bozdagi; Anna Matynia; Marcin Balcerzyk; Pawel Okulski; Joanna Dzwonek; Rui M Costa; Alcino J Silva; Leszek Kaczmarek; George W Huntley
Matrix metalloproteinase-9 is required for hippocampal late-phase long-term potentiation and memory.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(7):1923-34.
2006: Shusaku Uchida; S Sakai; T Furuichi; Hiroshi Hosoda; K Toyota; T Ishii; Aya Kitamoto; M Sekine; K Koike; Shoichi Masushige; Geoffrey G Murphy; Alcino J Silva; Satoshi Kida
Tight regulation of transgene expression by tetracycline-dependent activator and repressor in brain.
Genes, brain, and behavior 2006;5(1):96-106.
2006: Adele P Chen; MASUO OHNO; peter giese; Ralf Kühn; Rachel L Chen; Alcino J Silva
Forebrain-specific knockout of B-raf kinase leads to deficits in hippocampal long-term potentiation, learning, and memory.
Journal of neuroscience research 2006;83(1):28-38.
2005: Weidong Li; Yijun Cui; Steven A Kushner; Robert A M Brown; J David Jentsch; Paul W Frankland; Tyrone D Cannon; Alcino J Silva
The HMG-CoA reductase inhibitor lovastatin reverses the learning and attention deficits in a mouse model of neurofibromatosis type 1.
Current biology : CB 2005;15(21):1961-7.
2005: Steven A Kushner; Ype Elgersma; Geoffrey G Murphy; Dick Jaarsma; Geeske M van Woerden; Mohammad Reza Hojjati; Yijun Cui; Janelle C Leboutillier; Diano F Marrone; Esther S Choi; Chris I De Zeeuw; Ted L Petit; Lucas Pozzo-Miller; Alcino J Silva
Modulation of presynaptic plasticity and learning by the H-ras/extracellular signal-regulated kinase/synapsin I signaling pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(42):9721-34.
2005: Rui M Costa; Camilla Drew; Alcino J Silva
Notch to remember.
Trends in neurosciences 2005;28(8):429-35.
2005: MASUO OHNO; Wilbur Tseng; Alcino J Silva; John F Disterhoft
Trace eyeblink conditioning requires the hippocampus but not autophosphorylation of alphaCaMKII in mice.
Learning & memory (Cold Spring Harbor, N.Y.) 2005;12(3):211-5.
2005: Dan Ehninger; Anna Matynia; Alcino J Silva
Trafficking in emotions.
Nature neuroscience 2005;8(5):548-50.
2004: Geoffrey G Murphy; Nikolai B Fedorov; peter giese; MASUO OHNO; Eugenia Friedman; Rachel Chen; Alcino J Silva
Increased neuronal excitability, synaptic plasticity, and learning in aged Kvbeta1.1 knockout mice.
Current biology : CB 2004;14(21):1907-15.
2004: Brian J Wiltgen; Robert A M Brown; Lynn E Talton; Alcino J Silva
New circuits for old memories: the role of the neocortex in consolidation.
Neuron 2004;44(1):101-8.
2004: Inbal Israely; Rui M Costa; Cui Wei Xie; Alcino J Silva; Kenneth S Kosik; Xin Liu
Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction.
Current biology : CB 2004;14(18):1657-63.
2004: Sheena A Josselyn; Satoshi Kida; Alcino J Silva
Inducible repression of CREB function disrupts amygdala-dependent memory.
Neurobiology of learning and memory 2004;82(2):159-63.
2004: Akinobu Suzuki; Sheena A Josselyn; Paul W Frankland; Shoichi Masushige; Alcino J Silva; Satoshi Kida
Memory reconsolidation and extinction have distinct temporal and biochemical signatures.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(20):4787-95.
2004: Paul W Frankland; Bruno Bontempi; Lynn E Talton; Leszek Kaczmarek; Alcino J Silva
The involvement of the anterior cingulate cortex in remote contextual fear memory.
Science (New York, N.Y.) 2004;304(5672):881-3.
2004: Robert Brown; Alcino J Silva
Molecular and cellular cognition; the unraveling of memory retrieval.
Cell 2004;117(1):3-4.
2004: Paul W Frankland; Sheena A Josselyn; Stephan Anagnostaras; Jeffrey H Kogan; Eiki Takahashi; Alcino J Silva
Consolidation of CS and US representations in associative fear conditioning.
Hippocampus 2004;14(5):557-69.
2003: Jianpeng Wang; Keqin Ren; Javier Pérez; Alcino J Silva; Sandra Peña de Ortiz
The antimetabolite ara-CTP blocks long-term memory of conditioned taste aversion.
Learning & memory (Cold Spring Harbor, N.Y.) 2003;10(6):503-9.
2003: Rui M Costa; Tasuku Honjo; Alcino J Silva
Learning and memory deficits in Notch mutant mice.
Current biology : CB 2003;13(15):1348-54.
2003: Bruno Bozon; Aine Kelly; Sheena A Josselyn; Alcino J Silva; Sabrina Davis; Serge Laroche
MAPK, CREB and zif268 are all required for the consolidation of recognition memory.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2003;358(1432):805-14.
2003: Paul W Frankland; MASUO OHNO; Eiki Takahashi; Adele R Chen; Rui M Costa; Steven A Kushner; Alcino J Silva
Pharmacologically regulated induction of silent mutations (PRISM): combined pharmacological and genetic approaches for learning and memory.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2003;9(2):104-9.
2003: Ajay Dhaka; Rui M Costa; Hailiang Hu; Dwain K Irvin; Apoor Patel; Harley I Kornblum; Alcino J Silva; Thomas J O'Dell; John Colicelli
The RAS effector RIN1 modulates the formation of aversive memories.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(3):748-57.
2003: Rui M Costa; Alcino J Silva
Mouse models of neurofibromatosis type I: bridging the GAP.
Trends in molecular medicine 2003;9(1):19-23.
2003: Alcino J Silva
Molecular and cellular cognitive studies of the role of synaptic plasticity in memory.
Journal of neurobiology 2003;54(1):224-37.
2003: Stephan Anagnostaras; Geoffrey G Murphy; Susan E Hamilton; Scott L Mitchell; Nancy P Rahnama; Neil M Nathanson; Alcino J Silva
Selective cognitive dysfunction in acetylcholine M1 muscarinic receptor mutant mice.
Nature neuroscience 2003;6(1):51-8.
2002: Ype Elgersma; Nikolai B Fedorov; Sami Ikonen; Esther S Choi; Minetta Elgersma; Ofelia M Carvalho; peter giese; Alcino J Silva
Inhibitory autophosphorylation of CaMKII controls PSD association, plasticity, and learning.
Neuron 2002;36(3):493-505.
2002: Sharif A Taha; Jessica L Hanover; Alcino J Silva; Michael P Stryker
Autophosphorylation of alphaCaMKII is required for ocular dominance plasticity.
Neuron 2002;36(3):483-91.
2002: Alcino J Silva; Sheena A Josselyn
The molecules of forgetfulness.
Nature 2002;418(6901):929-30.
2002: Rui M Costa; Alcino J Silva
Molecular and cellular mechanisms underlying the cognitive deficits associated with neurofibromatosis 1.
Journal of child neurology 2002;17(8):622-6; discussion 627-9, 646-51.
2002: MASUO OHNO; Paul W Frankland; Alcino J Silva
A pharmacogenetic inducible approach to the study of NMDA/alphaCaMKII signaling in synaptic plasticity.
Current biology : CB 2002;12(8):654-6.
2002: Satoshi Kida; Sheena A Josselyn; Sandra Peña de Ortiz; Jeffrey H Kogan; Itzamarie Chevere; Shoichi Masushige; Alcino J Silva
CREB required for the stability of new and reactivated fear memories.
Nature neuroscience 2002;5(4):348-55.
2002: Maria I Givogri; Rui M Costa; Vilma Schonmann; Alcino J Silva; Anthony T Campagnoni; Ernesto R Bongarzone
Central nervous system myelination in mice with deficient expression of Notch1 receptor.
Journal of neuroscience research 2002;67(3):309-20.
2002: Rui M Costa; Nikolai B Federov; Jeff H Kogan; Geoffrey G Murphy; Joel Stern; MASUO OHNO; Raju Kucherlapati; Tyler Jacks; Alcino J Silva
Mechanism for the learning deficits in a mouse model of neurofibromatosis type 1.
Nature 2002;415(6871):526-30.
2002: Anna Matynia; Steven A Kushner; Alcino J Silva
Genetic approaches to molecular and cellular cognition: a focus on LTP and learning and memory.
Annual review of genetics 2002;36():687-720.
2001: MASUO OHNO; Paul W Frankland; Adele P Chen; Rui M Costa; Alcino J Silva
Inducible, pharmacogenetic approaches to the study of learning and memory.
Nature neuroscience 2001;4(12):1238-43.
2001: Anna Matynia; Stephan Anagnostaras; Alcino J Silva
Weaving the molecular and cognitive strands of memory.
Neuron 2001;32(4):557-9.
2001: peter giese; E Friedman; J B Telliez; Nikolai B Fedorov; M Wines; L A Feig; Alcino J Silva
Hippocampus-dependent learning and memory is impaired in mice lacking the Ras-guanine-nucleotide releasing factor 1 (Ras-GRF1).
Neuropharmacology 2001;41(6):791-800.
2001: Tony A Pham; John L R Rubenstein; Alcino J Silva; Daniel R Storm; Michael P Stryker
The CRE/CREB pathway is transiently expressed in thalamic circuit development and contributes to refinement of retinogeniculate axons.
Neuron 2001;31(3):409-20.
2001: Paul W Frankland; C O'Brien; MASUO OHNO; Alfredo Kirkwood; Alcino J Silva
Alpha-CaMKII-dependent plasticity in the cortex is required for permanent memory.
Nature 2001;411(6835):309-13.
2001: Susan E Hamilton; S N Hardouin; Stephan Anagnostaras; Geoffrey G Murphy; Keith N Richmond; Alcino J Silva; Eric O Feigl; Neil M Nathanson
Alteration of cardiovascular and neuronal function in M1 knockout mice.
Life sciences 2001;68(22-23):2489-93.
2001: Rui M Costa; T Yang; duong huynh; Stef pulst; D H Viskochil; Alcino J Silva; C I Brannan
Learning deficits, but normal development and tumor predisposition, in mice lacking exon 23a of Nf1.
Nature genetics 2001;27(4):399-405.
2000: Gregory D Ferguson; Stephan Anagnostaras; Alcino J Silva; Harvey R Herschman
Deficits in memory and motor performance in synaptotagmin IV mutant mice.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5598-603.
2000: Alcino J Silva; Ype Elgersma; Rui M Costa
Molecular and cellular mechanisms of cognitive function: implications for psychiatric disorders.
Biological psychiatry 2000;47(3):200-9.
2000: Stephan Anagnostaras; Sheena A Josselyn; Paul W Frankland; Alcino J Silva
Computer-assisted behavioral assessment of Pavlovian fear conditioning in mice.
Learning & memory (Cold Spring Harbor, N.Y.) 2000;7(1):58-72.
2000: Jeffrey H Kogan; Paul W Frankland; Alcino J Silva
Long-term memory underlying hippocampus-dependent social recognition in mice.
Hippocampus 2000;10(1):47-56.
1999: Alcino J Silva; Geoffrey G Murphy
cAMP and memory: a seminal lesson from Drosophila and Aplysia.
Brain research bulletin 1999;50(5-6):441-2.
1999: Ype Elgersma; Alcino J Silva
Molecular mechanisms of synaptic plasticity and memory.
Current opinion in neurobiology 1999;9(2):209-13.
1999: Y H Cho; E Friedman; Alcino J Silva
Ibotenate lesions of the hippocampus impair spatial learning but not contextual fear conditioning in mice.
Behavioural brain research 1999;98(1):77-87.
1998: Alcino J Silva; Ype Elgersma; E Friedman; J Stern; Jeffrey H Kogan
A mouse model for learning and memory defects associated with neurofibromatosis type I.
Pathologie-biologie 1998;46(9):697-8.
1998: peter giese; Johan F Storm; D Reuter; Nikolai B Fedorov; LR Shao; Torsten Leicher; Olaf Pongs; Alcino J Silva
Reduced K+ channel inactivation, spike broadening, and after-hyperpolarization in Kvbeta1.1-deficient mice with impaired learning.
Learning & memory (Cold Spring Harbor, N.Y.) 1998;5(4-5):257-73.
1998: Paul W Frankland; V Cestari; Robert Filipkowski; R J McDonald; Alcino J Silva
The dorsal hippocampus is essential for context discrimination but not for contextual conditioning.
Behavioral neuroscience 1998;112(4):863-74.
1998: Alcino J Silva; peter giese; Nikolai B Fedorov; Paul W Frankland; Jeffrey H Kogan
Molecular, cellular, and neuroanatomical substrates of place learning.
Neurobiology of learning and memory 1998;70(1-2):44-61.
1998: peter giese; Nikolai B Fedorov; Robert Filipkowski; Alcino J Silva
Autophosphorylation at Thr286 of the alpha calcium-calmodulin kinase II in LTP and learning.
Science (New York, N.Y.) 1998;279(5352):870-3.
1998: Alcino J Silva; Jeffrey H Kogan; Paul W Frankland; Satoshi Kida
CREB and memory.
Annual review of neuroscience 1998;21():127-48.
1997: Alcino J Silva; Paul W Frankland; Z Marowitz; E Friedman; G S Laszlo; D Cioffi; T Jacks; R Bourtchuladze; G Lazlo
A mouse model for the learning and memory deficits associated with neurofibromatosis type I.
Nature genetics 1997;15(3):281-4.
1997: Alcino J Silva; A M Smith; peter giese
Gene targeting and the biology of learning and memory.
Annual review of genetics 1997;31():527-46.
1997: Jeffrey H Kogan; Paul W Frankland; J A Blendy; J Coblentz; Z Marowitz; G Schütz; Alcino J Silva
Spaced training induces normal long-term memory in CREB mutant mice.
Current biology : CB 1997;7(1):1-11.
1996: Alcino J Silva; T W Rosahl; Paul F Chapman; Z Marowitz; E Friedman; Paul W Frankland; Vincenzo Cestari; D Cioffi; T C Südhof; R Bourtchuladze
Impaired learning in mice with abnormal short-lived plasticity.
Current biology : CB 1996;6(11):1509-18.
1996: J A Gordon; D Cioffi; Alcino J Silva; Michael P Stryker
Deficient plasticity in the primary visual cortex of alpha-calcium/calmodulin-dependent protein kinase II mutant mice.
Neuron 1996;17(3):491-9.
1996: Alcino J Silva; N Fedorov; Jeffrey H Kogan; Paul W Frankland; J Coblentz; R Lundsten; E Friedman; A Smith; Y Cho; peter giese
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Neuron 1995;14(3):591-7.
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Deficient long-term memory in mice with a targeted mutation of the cAMP-responsive element-binding protein.
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Plastic genes are in!
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