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Pamela Silver

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Saccharomyces cerevisiae

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Daniel F Selgrade; Florian Lienert; Jason J Lohmueller; Pamela A Silver
Protein scaffold-activated protein trans-splicing in Mammalian cells.
Qingqing Wang; G Adelmant; Jarrod A Marto; Michael J Moore; Pamela A Silver
PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth.
Anna H Chen; Pamela A Silver
Designing biological compartmentalization.

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All Publications

2013: Daniel F Selgrade; Florian Lienert; Jason J Lohmueller; Pamela A Silver
Protein scaffold-activated protein trans-splicing in Mammalian cells.
Journal of the American Chemical Society 2013;135(20):7713-9.
2013: Qingqing Wang; G Adelmant; Jarrod A Marto; Michael J Moore; Pamela A Silver
PQBP1, a factor linked to intellectual disability, affects alternative splicing associated with neurite outgrowth.
Genes & development 2013;27(6):615-26.
2012: Anna H Chen; Pamela A Silver
Designing biological compartmentalization.
Trends in cell biology 2012;22(12):662-70.
2012: Daniel C Ducat; Pamela A Silver
Improving carbon fixation pathways.
Current opinion in chemical biology 2012;16(3-4):337-44.
2012: Abhishek Garg; Jason J Lohmueller; Pamela A Silver; Thomas Z Armel
Engineering synthetic TAL effectors with orthogonal target sites.
Nucleic acids research 2012;40(15):7584-95.
2012: Devin R Burrill; Mara C Inniss; Patrick M Boyle; Pamela A Silver
Synthetic memory circuits for tracking human cell fate.
Genes & development 2012;26(13):1486-97.
2012: Christina M Agapakis; Patrick M Boyle; Pamela A Silver
Natural strategies for the spatial optimization of metabolism in synthetic biology.
Nature chemical biology 2012;8(6):527-35.
2012: Jason J Lohmueller; Thomas Z Armel; Pamela A Silver
A tunable zinc finger-based framework for Boolean logic computation in mammalian cells.
Nucleic acids research 2012;40(11):5180-7.
2012: Patrick M Boyle; Pamela A Silver
Parts plus pipes: synthetic biology approaches to metabolic engineering.
Metabolic engineering 2012;14(3):223-32.
2012: Anna H Chen; Bruno Afonso; Pamela A Silver; David F Savage
Spatial and temporal organization of chromosome duplication and segregation in the cyanobacterium Synechococcus elongatus PCC 7942.
PloS one 2012;7(10):e47837.
2012: Patrick M Boyle; Tamara J Brenner; Devin R Burrill; George M Church; Aaron Deardon; Jonathan G Dewerd; Michael A Gedeon; Karmella A Haynes; Mara C Inniss; Oliver Medvedik; Morgan L Paull; Jacqueline Y Quinn; Anugraha M Raman; Kurt Schellenberg; Jagesh V Shah; Mark R Theilmann; Alain Viel; Lu Wang; Julia C Winn; Christina M Agapakis; Pamela A Silver
A BioBrick compatible strategy for genetic modification of plants.
Journal of biological engineering 2012;6(1):8.
2012: Keiji Nishida; Pamela A Silver
Induction of biogenic magnetization and redox control by a component of the target of rapamycin complex 1 signaling pathway.
PLoS biology 2012;10(2):e1001269.
2011: Devin R Burrill; Pamela A Silver
Recording cellular experiences of DNA damage.
Cell cycle (Georgetown, Tex.) 2011;10(15):2410-1.
2011: Camille J Delebecque; Ariel B Lindner; Pamela A Silver; Faisal A Aldaye
Organization of intracellular reactions with rationally designed RNA assemblies.
Science (New York, N.Y.) 2011;333(6041):470-4.
2011: Daniel C Ducat; Gairik Sachdeva; Pamela A Silver
Rewiring hydrogenase-dependent redox circuits in cyanobacteria.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(10):3941-6.
2011: Devin R Burrill; Pamela A Silver
Synthetic circuit identifies subpopulations with sustained memory of DNA damage.
Genes & development 2011;25(5):434-9.
2011: Daniel C Ducat; Jeffrey C Way; Pamela A Silver
Engineering cyanobacteria to generate high-value products.
Trends in biotechnology 2011;29(2):95-103.
2011: D R Burrill; P M Boyle; Pamela A Silver
A new approach to an old problem: synthetic biology tools for human disease and metabolism.
Cold Spring Harbor symposia on quantitative biology 2011;76():145-54.
2011: Zeev Waks; Allon M Klein; Pamela A Silver
Cell-to-cell variability of alternative RNA splicing.
Molecular systems biology 2011;7():506.
2011: Buz Barstow; Patrick M Boyle; Gerald Grandl; Pamela A Silver; Christina M Agapakis; Edwin H Wintermute
A synthetic system links FeFe-hydrogenases to essential E. coli sulfur metabolism.
Journal of biological engineering 2011;5():7.
2011: Christina M Agapakis; Henrike Niederholtmeyer; Ramil R Noche; Tami D Lieberman; Sean G Megason; Jeffrey C Way; Pamela A Silver
Towards a synthetic chloroplast.
PloS one 2011;6(4):e18877.
2010: Edwin H Wintermute; Pamela A Silver
Dynamics in the mixed microbial concourse.
Genes & development 2010;24(23):2603-14.
2010: Christina M Agapakis; Pamela A Silver
Modular electron transfer circuits for synthetic biology: insulation of an engineered biohydrogen pathway.
Bioengineered bugs 2010;1(6):413-8.
2010: Faisal A Aldaye; William T Senapedis; Pamela A Silver; Jeffrey C Way
A structurally tunable DNA-based extracellular matrix.
Journal of the American Chemical Society 2010;132(42):14727-9.
2010: Edwin H Wintermute; Pamela A Silver
Emergent cooperation in microbial metabolism.
Molecular systems biology 2010;6():407.
2010: Michael J Moore; Qingqing Wang; Caleb J Kennedy; Pamela A Silver
An alternative splicing network links cell-cycle control to apoptosis.
Cell 2010;142(4):625-36.
2010: Henrike Niederholtmeyer; Bernd T Wolfstädter; David F Savage; Pamela A Silver; Jeffrey C Way
Engineering cyanobacteria to synthesize and export hydrophilic products.
Applied and environmental microbiology 2010;76(11):3462-6.
2010: Bruno Afonso; Pamela A Silver; Caroline M Ajo-Franklin
A synthetic circuit for selectively arresting daughter cells to create aging populations.
Nucleic acids research 2010;38(8):2727-35.
2010: Noah D Taylor; Jeffrey C Way; Pamela A Silver; Pablo Cironi
Anti-glycophorin single-chain Fv fusion to low-affinity mutant erythropoietin improves red blood cell-lineage specificity.
Protein engineering, design & selection : PEDS 2010;23(4):251-60.
2010: David F Savage; Bruno Afonso; Anna H Chen; Pamela A Silver
Spatially ordered dynamics of the bacterial carbon fixation machinery.
Science (New York, N.Y.) 2010;327(5970):1258-61.
2010: Devin R Burrill; Pamela A Silver
Making cellular memories.
Cell 2010;140(1):13-8.
2010: Christina M Agapakis; Daniel C Ducat; Patrick M Boyle; Edwin H Wintermute; Jeffrey C Way; Pamela A Silver
Insulation of a synthetic hydrogen metabolism circuit in bacteria.
Journal of biological engineering 2010;4():3.
2009: Karmella A Haynes; Pamela A Silver
Eukaryotic systems broaden the scope of synthetic biology.
The Journal of cell biology 2009;187(5):589-96.
2009: Caleb J Kennedy; Patrick M Boyle; Zeev Waks; Pamela A Silver
Systems-level engineering of nonfermentative metabolism in yeast.
Genetics 2009;183(1):385-97.
2009: Patrick M Boyle; Pamela A Silver
Harnessing nature's toolbox: regulatory elements for synthetic biology.
Journal of the Royal Society, Interface / the Royal Society 2009;6 Suppl 4():S535-46.
2009: Christina M Agapakis; Pamela A Silver
Synthetic biology: exploring and exploiting genetic modularity through the design of novel biological networks.
Molecular bioSystems 2009;5(7):704-13.
2009: Jessica A Hurt; Bob Obar; Bo Zhai; Natalie G Farny; Steven P Gygi; Pamela A Silver
A conserved CCCH-type zinc finger protein regulates mRNA nuclear adenylation and export.
The Journal of cell biology 2009;185(2):265-77.
2009: Zeev Waks; Pamela A Silver
Engineering a synthetic dual-organism system for hydrogen production.
Applied and environmental microbiology 2009;75(7):1867-75.
2008: Jessica A Hurt; Pamela A Silver
mRNA nuclear export and human disease.
Disease models & mechanisms 2008;1(2-3):103-8.
2008: Ian A Swinburne; David G Miguez; Dirk Landgraf; Pamela A Silver
Intron length increases oscillatory periods of gene expression in animal cells.
Genes & development 2008;22(17):2342-6.
2008: Pablo Cironi; Ian A Swinburne; Pamela A Silver
Enhancement of cell type specificity by quantitative modulation of a chimeric ligand.
The Journal of biological chemistry 2008;283(13):8469-76.
2008: Ian A Swinburne; Pamela A Silver
Intron delays and transcriptional timing during development.
Developmental cell 2008;14(3):324-30.
2008: Christopher R Brown; Caleb J Kennedy; Valerie A Delmar; Douglass J Forbes; Pamela A Silver
Global histone acetylation induces functional genomic reorganization at mammalian nuclear pore complexes.
Genes & development 2008;22(5):627-39.
2008: Michael J Moore; Pamela A Silver
Global analysis of mRNA splicing.
RNA (New York, N.Y.) 2008;14(2):197-203.
2008: David F Savage; Jeffrey Way; Pamela A Silver
Defossiling fuel: how synthetic biology can transform biofuel production.
ACS chemical biology 2008;3(1):13-6.
2008: Seth Frietze; Mathieu Lupien; Pamela A Silver; Myles Brown
CARM1 regulates estrogen-stimulated breast cancer growth through up-regulation of E2F1.
Cancer research 2008;68(1):301-6.
2008: Natalie G Farny; Jessica A Hurt; Pamela A Silver
Definition of global and transcript-specific mRNA export pathways in metazoans.
Genes & development 2008;22(1):66-78.
2008: Suzanne Komili; Pamela A Silver
Coupling and coordination in gene expression processes: a systems biology view.
Nature reviews. Genetics 2008;9(1):38-48.
2007: Suzanne Komili; Natalie G Farny; Frederick P Roth; Pamela A Silver
Functional specificity among ribosomal proteins regulates gene expression.
Cell 2007;131(3):557-71.
2007: Pamela A Silver; Jeffrey C Way
Molecular systems biology in drug development.
Clinical pharmacology and therapeutics 2007;82(5):586-90.
2007: Caroline M Ajo-Franklin; David A Drubin; Julian A Eskin; Elaine P S Gee; Dirk Landgraf; Ira Phillips; Pamela A Silver
Rational design of memory in eukaryotic cells.
Genes & development 2007;21(18):2271-6.
2007: Adrienne E McKee; Pamela A Silver
Systems perspectives on mRNA processing.
Cell research 2007;17(7):581-90.
2007: Zhe Zhou; Pablo Cironi; Alison J Lin; Yangqing Xu; Sinisa Hrvatin; David E Golan; Pamela A Silver; Christopher T Walsh; Jun Yin
Genetically encoded short peptide tags for orthogonal protein labeling by Sfp and AcpS phosphopantetheinyl transferases.
ACS chemical biology 2007;2(5):337-46.
2007: Christopher R Brown; Pamela A Silver
Transcriptional regulation at the nuclear pore complex.
Current opinion in genetics & development 2007;17(2):100-6.
2007: David A Drubin; Jeffrey C Way; Pamela A Silver
Designing biological systems.
Genes & development 2007;21(3):242-54.
2007: Adrienne E McKee; Nicola Neretti; Luis E Carvalho; Clifford A Meyer; Edward A Fox; Alexander S Brodsky; Pamela A Silver
Exon expression profiling reveals stimulus-mediated exon use in neural cells.
Genome biology 2007;8(8):R159.
2006: Michael J Moore; Elissa M Schwartzfarb; Pamela A Silver; Michael Yu
Differential recruitment of the splicing machinery during transcription predicts genome-wide patterns of mRNA splicing.
Molecular cell 2006;24(6):903-15.
2006: Michael Yu; Dudley W Lamming; Julian A Eskin; David A Sinclair; Pamela A Silver
The role of protein arginine methylation in the formation of silent chromatin.
Genes & development 2006;20(23):3249-54.
2006: Jason S Carroll; Clifford A Meyer; Jun Song; Wei Li; Timothy Geistlinger; Jérôme Eeckhoute; Alexander S Brodsky; Erika Krasnickas Keeton; Kirsten C Fertuck; Giles F Hall; Qianben Wang; Stefan Bekiranov; Victor Sementchenko; Edward A Fox; Pamela A Silver; Thomas Gingeras; Xiaole (Shirley) Liu; Myles Brown
Genome-wide analysis of estrogen receptor binding sites.
Nature genetics 2006;38(11):1289-97.
2006: Kathryn L Auld; Amy L Hitchcock; Hugh K Doherty; Seth Frietze; Linda S Huang; Pamela A Silver
The conserved ATPase Get3/Arr4 modulates the activity of membrane-associated proteins in Saccharomyces cerevisiae.
Genetics 2006;174(1):215-27.
2006: Kathryn L Auld; Pamela A Silver
Transcriptional regulation by the proteasome as a mechanism for cellular protein homeostasis.
Cell cycle (Georgetown, Tex.) 2006;5(14):1503-5.
2006: Ian A Swinburne; Clifford A Meyer; Xiaole (Shirley) Liu; Pamela A Silver; Alexander S Brodsky
Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcription.
Genome research 2006;16(7):912-21.
2006: Kathryn L Auld; Christopher R Brown; Jason M Casolari; Suzanne Komili; Pamela A Silver
Genomic association of the proteasome demonstrates overlapping gene regulatory activity with transcription factor substrates.
Molecular cell 2006;21(6):861-71.
2006: Nick Vandegraaff; Eric Devroe; Fanny Turlure; Pamela A Silver; Alan Engelman
Biochemical and genetic analyses of integrase-interacting proteins lens epithelium-derived growth factor (LEDGF)/p75 and hepatoma-derived growth factor related protein 2 (HRP2) in preintegration complex function and HIV-1 replication.
Virology 2006;346(2):415-26.
2006: Adrienne E McKee; Pamela A Silver
Systems biology of gene regulation fulfills its promise.
Genome biology 2006;7(5):316.
2006: David A Drubin; Arman M Garakani; Pamela A Silver
Motion as a phenotype: the use of live-cell imaging and machine visual screening to characterize transcription-dependent chromosome dynamics.
BMC cell biology 2006;7():19.
2005: Michael A Robinson; Sunghyouk Park; Zhen-Yu J Sun; Pamela A Silver; Gerhard Wagner; James M Hogle
Multiple conformations in the ligand-binding site of the yeast nuclear pore-targeting domain of Nup116p.
The Journal of biological chemistry 2005;280(42):35723-32.
2005: Jason S Carroll; Xiaole (Shirley) Liu; Alexander S Brodsky; Wei Li; Clifford A Meyer; Anna J Szary; Jérôme Eeckhoute; Wenlin Shao; Eli V Hestermann; Timothy Geistlinger; Edward A Fox; Pamela A Silver; Myles Brown
Chromosome-wide mapping of estrogen receptor binding reveals long-range regulation requiring the forkhead protein FoxA1.
Cell 2005;122(1):33-43.
2005: Sunghyouk Park; Rivka Isaacson; Hyoung Tae Kim; Pamela A Silver; Gerhard Wagner
Ufd1 exhibits the AAA-ATPase fold with two distinct ubiquitin interaction sites.
Structure (London, England : 1993) 2005;13(7):995-1005.
2005: Jason M Casolari; Christopher R Brown; David A Drubin; Oliver J Rando; Pamela A Silver
Developmentally induced changes in transcriptional program alter spatial organization across chromosomes.
Genes & development 2005;19(10):1188-98.
2005: Frank Schroeder; Tweeny R Kau; Pamela A Silver; Jon Clardy
The psammaplysenes, specific inhibitors of FOXO1a nuclear export.
Journal of natural products 2005;68(4):574-6.
2005: Eric Devroe; Pamela A Silver; Alan Engelman
HIV-1 incorporates and proteolytically processes human NDR1 and NDR2 serine-threonine kinases.
Virology 2005;331(1):181-9.
2005: Alexander S Brodsky; Clifford A Meyer; Ian A Swinburne; Giles Hall; Benjamin J Keenan; Xiaole (Shirley) Liu; Edward A Fox; Pamela A Silver
Genomic mapping of RNA polymerase II reveals sites of co-transcriptional regulation in human cells.
Genome biology 2005;6(8):R64.
2005: Adrienne E McKee; Emmanuel Minet; Charlene A. Stern; Shervin Riahi; Charles D Stiles; Pamela A Silver
A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
BMC developmental biology 2005;5():14.
2004: Haley Hieronymus; Pamela A Silver
A systems view of mRNP biology.
Genes & development 2004;18(23):2845-60.
2004: Richard Lu; Ana Limón; Eric Devroe; Pamela A Silver; Peter Cherepanov; Alan Engelman
Class II integrase mutants with changes in putative nuclear localization signals are primarily blocked at a postnuclear entry step of human immunodeficiency virus type 1 replication.
Journal of virology 2004;78(23):12735-46.
2004: Peter Cherepanov; Eric Devroe; Pamela A Silver; Alan Engelman
Identification of an evolutionarily conserved domain in human lens epithelium-derived growth factor/transcriptional co-activator p75 (LEDGF/p75) that binds HIV-1 integrase.
The Journal of biological chemistry 2004;279(47):48883-92.
2004: Haley Hieronymus; Michael Yu; Pamela A Silver
Genome-wide mRNA surveillance is coupled to mRNA export.
Genes & development 2004;18(21):2652-62.
2004: Fanny Turlure; Eric Devroe; Pamela A Silver; Alan Engelman
Human cell proteins and human immunodeficiency virus DNA integration.
Frontiers in bioscience : a journal and virtual library 2004;9():3187-208.
2004: Michael Yu; François Bachand; Anne E McBride; Suzanne Komili; Jason M Casolari; Pamela A Silver
Arginine methyltransferase affects interactions and recruitment of mRNA processing and export factors.
Genes & development 2004;18(16):2024-35.
2004: François Bachand; Pamela A Silver
PRMT3 is a ribosomal protein methyltransferase that affects the cellular levels of ribosomal subunits.
The EMBO journal 2004;23(13):2641-50.
2004: Eric Devroe; Hediye Erdjument-Bromage; Paul Tempst; Pamela A Silver
Human Mob proteins regulate the NDR1 and NDR2 serine-threonine kinases.
The Journal of biological chemistry 2004;279(23):24444-51.
2004: Adrienne E McKee; Pamela A Silver
REF-ereeing the cytoplasmic fate of mRNA via nuclear export.
Developmental cell 2004;6(6):740-2.
2004: Jason M Casolari; Christopher R Brown; Suzanne Komili; Jason West; Haley Hieronymus; Pamela A Silver
Genome-wide localization of the nuclear transport machinery couples transcriptional status and nuclear organization.
Cell 2004;117(4):427-39.
2004: Jason M Casolari; Pamela A Silver
Guardian at the gate: preventing unspliced pre-mRNA export.
Trends in cell biology 2004;14(5):222-5.
2004: Eric Devroe; Pamela A Silver
Therapeutic potential of retroviral RNAi vectors.
Expert opinion on biological therapy 2004;4(3):319-27.
2004: Tweeny R Kau; Jeffrey C Way; Pamela A Silver
Nuclear transport and cancer: from mechanism to intervention.
Nature reviews. Cancer 2004;4(2):106-17.
2003: Tweeny R Kau; Frank Schroeder; Shivapriya Ramaswamy; Cheryl L Wojciechowski; Jean J Zhao; Thomas M Roberts; Jon Clardy; William R Sellers; Pamela A Silver
A chemical genetic screen identifies inhibitors of regulated nuclear export of a Forkhead transcription factor in PTEN-deficient tumor cells.
Cancer cell 2003;4(6):463-76.
2003: Stephen Haggarty; Kathryn M Koeller; Tweeny R Kau; Pamela A Silver; Michel Roberge; Stuart L Schreiber
Small molecule modulation of the human chromatid decatenation checkpoint.
Chemistry & biology 2003;10(12):1267-79.
2003: Eric Devroe; Alan Engelman; Pamela A Silver
Intracellular transport of human immunodeficiency virus type 1 integrase.
Journal of cell science 2003;116(Pt 21):4401-8.
2003: Amy L Hitchcock; Kathryn L Auld; Steven P Gygi; Pamela A Silver
A subset of membrane-associated proteins is ubiquitinated in response to mutations in the endoplasmic reticulum degradation machinery.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(22):12735-40.
2003: Elissa P Lei; Charlene A. Stern; Birthe Fahrenkrog; Heike Krebber; Terence I Moy; Ueli Aebi; Pamela A Silver
Sac3 is an mRNA export factor that localizes to cytoplasmic fibrils of nuclear pore complex.
Molecular biology of the cell 2003;14(3):836-47.
2003: Haley Hieronymus; Pamela A Silver
Genome-wide analysis of RNA-protein interactions illustrates specificity of the mRNA export machinery.
Nature genetics 2003;33(2):155-61.
2003: Tweeny R Kau; Pamela A Silver
Nuclear transport as a target for cell growth.
Drug discovery today 2003;8(2):78-85.
2002: Alexander S Brodsky; Pamela A Silver
A microbead-based system for identifying and characterizing RNA-protein interactions by flow cytometry.
Molecular & cellular proteomics : MCP 2002;1(12):922-9.
2002: Marc Damelin; Pamela A Silver
In situ analysis of spatial relationships between proteins of the nuclear pore complex.
Biophysical journal 2002;83(6):3626-36.
2002: Elissa P Lei; Pamela A Silver
Intron status and 3'-end formation control cotranscriptional export of mRNA.
Genes & development 2002;16(21):2761-6.
2002: Ana Limón; Eric Devroe; Richard Lu; Hina Z Ghory; Pamela A Silver; Alan Engelman
Nuclear localization of human immunodeficiency virus type 1 preintegration complexes (PICs): V165A and R166A are pleiotropic integrase mutants primarily defective for integration, not PIC nuclear import.
Journal of virology 2002;76(21):10598-607.
2002: Eric Devroe; Pamela A Silver
Retrovirus-delivered siRNA.
BMC biotechnology 2002;2():15.
2002: Terence I Moy; Pamela A Silver
Requirements for the nuclear export of the small ribosomal subunit.
Journal of cell science 2002;115(Pt 14):2985-95.
2002: Terence I Moy; Douglas R Boettner; Judith C Rhodes; Pamela A Silver; David S Askew
Identification of a role for Saccharomyces cerevisiae Cgr1p in pre-rRNA processing and 60S ribosome subunit synthesis.
Microbiology (Reading, England) 2002;148(Pt 4):1081-90.
2002: Marc Damelin; Itamar Simon; Terence I Moy; Boris Wilson; Suzanne Komili; Paul Tempst; Frederick P Roth; Richard A Young; Bradley R Cairns; Pamela A Silver
The genome-wide localization of Rsc9, a component of the RSC chromatin-remodeling complex, changes in response to stress.
Molecular cell 2002;9(3):563-73.
2002: Elissa P Lei; Pamela A Silver
Protein and RNA export from the nucleus.
Developmental cell 2002;2(3):261-72.
2002: Alexander S Brodsky; Pamela A Silver
Identifying proteins that affect mRNA localization in living cells.
Methods (San Diego, Calif.) 2002;26(2):151-5.
2002: Sandro R Valentini; Jason M Casolari; Carla C Oliveira; Pamela A Silver; Anne E McBride
Genetic interactions of yeast eukaryotic translation initiation factor 5A (eIF5A) reveal connections to poly(A)-binding protein and protein kinase C signaling.
Genetics 2002;160(2):393-405.
2002: Marc Damelin; Pamela A Silver; Anita H Corbett
Nuclear protein transport.
Methods in enzymology 2002;351():587-607.
2001: Amy L Hitchcock; Heike Krebber; Seth Frietze; A Lin; M Latterich; Pamela A Silver
The conserved npl4 protein complex mediates proteasome-dependent membrane-bound transcription factor activation.
Molecular biology of the cell 2001;12(10):3226-41.
2001: Elissa P Lei; Heike Krebber; Pamela A Silver
Messenger RNAs are recruited for nuclear export during transcription.
Genes & development 2001;15(14):1771-82.
2001: Anne E McBride; Pamela A Silver
State of the arg: protein methylation at arginine comes of age.
Cell 2001;106(1):5-8.
2001: JK Hood; William Hwang; Pamela A Silver
The Saccharomyces cerevisiae cyclin Clb2p is targeted to multiple subcellular locations by cis- and trans-acting determinants.
Journal of cell science 2001;114(Pt 3):589-97.
2000: Alexander S Brodsky; Pamela A Silver
Pre-mRNA processing factors are required for nuclear export.
RNA (New York, N.Y.) 2000;6(12):1737-49.
2000: VH Weiss; Anne E McBride; M A Soriano; David J Filman; Pamela A Silver; James M Hogle
The structure and oligomerization of the yeast arginine methyltransferase, Hmt1.
Nature structural biology 2000;7(12):1165-71.
2000: T Stage-Zimmermann; Ute Schmidt; Pamela A Silver
Factors affecting nuclear export of the 60S ribosomal subunit in vivo.
Molecular biology of the cell 2000;11(11):3777-89.
2000: E C Shen; T Stage-Zimmermann; P Chui; Pamela A Silver
7The yeast mRNA-binding protein Npl3p interacts with the cap-binding complex.
The Journal of biological chemistry 2000;275(31):23718-24.
2000: JK Hood; Pamela A Silver
Diverse nuclear transport pathways regulate cell proliferation and oncogenesis.
Biochimica et biophysica acta 2000;1471(1):M31-41.
2000: JK Hood; Jason M Casolari; Pamela A Silver
Nup2p is located on the nuclear side of the nuclear pore complex and coordinates Srp1p/importin-alpha export.
Journal of cell science 2000;113 ( Pt 8)():1471-80.
2000: Anne E McBride; VH Weiss; H K Kim; James M Hogle; Pamela A Silver
Analysis of the yeast arginine methyltransferase Hmt1p/Rmt1p and its in vivo function. Cofactor binding and substrate interactions.
The Journal of biological chemistry 2000;275(5):3128-36.
2000: Marc Damelin; Pamela A Silver
Mapping interactions between nuclear transport factors in living cells reveals pathways through the nuclear pore complex.
Molecular cell 2000;5(1):133-40.
1999: P Ferrigno; Pamela A Silver
Regulated nuclear localization of stress-responsive factors: how the nuclear trafficking of protein kinases and transcription factors contributes to cell survival.
Oncogene 1999;18(45):6129-34.
1999: H Morehouse; Robin M Buratowski; Pamela A Silver; Stephen Buratowski
The importin/karyopherin Kap114 mediates the nuclear import of TATA-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12542-7.
1999: Terence I Moy; Pamela A Silver
Nuclear export of the small ribosomal subunit requires the ran-GTPase cycle and certain nucleoporins.
Genes & development 1999;13(16):2118-33.
1999: Heike Krebber; T Taura; Lee Margaret; Pamela A Silver
Uncoupling of the hnRNP Npl3p from mRNAs during the stress-induced block in mRNA export.
Genes & development 1999;13(15):1994-2004.
1999: Sandro R Valentini; VH Weiss; Pamela A Silver
Arginine methylation and binding of Hrp1p to the efficiency element for mRNA 3'-end formation.
RNA (New York, N.Y.) 1999;5(2):272-80.
1999: M Seedorf; Marc Damelin; J Kahana; T Taura; Pamela A Silver
Interactions between a nuclear transporter and a subset of nuclear pore complex proteins depend on Ran GTPase.
Molecular and cellular biology 1999;19(2):1547-57.
1999: P Ferrigno; Pamela A Silver
Analysis of nuclear transport in vivo.
Methods in cell biology 1999;58():107-22.
1998: JK Hood; Pamela A Silver
Cse1p is required for export of Srp1p/importin-alpha from the nucleus in Saccharomyces cerevisiae.
The Journal of biological chemistry 1998;273(52):35142-6.
1998: P Ferrigno; Francesc Posas; D Koepp; H Saito; Pamela A Silver
Regulated nucleo/cytoplasmic exchange of HOG1 MAPK requires the importin beta homologs NMD5 and XPO1.
The EMBO journal 1998;17(19):5606-14.
1998: T Taura; Heike Krebber; Pamela A Silver
A member of the Ran-binding protein family, Yrb2p, is involved in nuclear protein export.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(13):7427-32.
1998: D M Koepp; Pamela A Silver
Nucleocytoplasmic transport and cell proliferation.
Biochimica et biophysica acta 1998;1377(2):M39-47.
1998: E C Shen; M F Henry; VH Weiss; Sandro R Valentini; Pamela A Silver; Lee Margaret
Arginine methylation facilitates the nuclear export of hnRNP proteins.
Genes & development 1998;12(5):679-91.
1997: T Taura; G Schlenstedt; Pamela A Silver
Yrb2p is a nuclear protein that interacts with Prp20p, a yeast Rcc1 homologue.
The Journal of biological chemistry 1997;272(50):31877-84.
1997: M Seedorf; Pamela A Silver
Importin/karyopherin protein family members required for mRNA export from the nucleus.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(16):8590-5.
1997: D H Wong; Anita H Corbett; H M Kent; M Stewart; Pamela A Silver
Interaction between the small GTPase Ran/Gsp1p and Ntf2p is required for nuclear transport.
Molecular and cellular biology 1997;17(7):3755-67.
1997: Anita H Corbett; Pamela A Silver
Nucleocytoplasmic transport of macromolecules.
Microbiology and molecular biology reviews : MMBR 1997;61(2):193-211.
1996: C DeHoratius; Pamela A Silver
Nuclear transport defects and nuclear envelope alterations are associated with mutation of the Saccharomyces cerevisiae NPL4 gene.
Molecular biology of the cell 1996;7(11):1835-55.
1996: D M Koepp; Pamela A Silver
A GTPase controlling nuclear trafficking: running the right way or walking RANdomly?
Cell 1996;87(1):1-4.
1996: Anita H Corbett; Pamela A Silver
The NTF2 gene encodes an essential, highly conserved protein that functions in nuclear transport in vivo.
The Journal of biological chemistry 1996;271(31):18477-84.
1996: M F Henry; Pamela A Silver
A novel methyltransferase (Hmt1p) modifies poly(A)+-RNA-binding proteins.
Molecular and cellular biology 1996;16(7):3668-78.
1996: D M Koepp; D H Wong; Anita H Corbett; Pamela A Silver
Dynamic localization of the nuclear import receptor and its interactions with transport factors.
The Journal of cell biology 1996;133(6):1163-76.
1996: Lee Margaret; M Henry; Pamela A Silver
A protein that shuttles between the nucleus and the cytoplasm is an important mediator of RNA export.
Genes & development 1996;10(10):1233-46.
1996: M Henry; C Z Borland; M Bossie; Pamela A Silver
Potential RNA binding proteins in Saccharomyces cerevisiae identified as suppressors of temperature-sensitive mutations in NPL3.
Genetics 1996;142(1):103-15.
1995: G Schlenstedt; D H Wong; D M Koepp; Pamela A Silver
Mutants in a yeast Ran binding protein are defective in nuclear transport.
The EMBO journal 1995;14(21):5367-78.
1995: J A Kahana; Bruce J Schnapp; Pamela A Silver
Kinetics of spindle pole body separation in budding yeast.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(21):9707-11.
1995: Anita H Corbett; D M Koepp; G Schlenstedt; Lee Margaret; A K Hopper; Pamela A Silver
Rna1p, a Ran/TC4 GTPase activating protein, is required for nuclear import.
The Journal of cell biology 1995;130(5):1017-26.
1995: J D Loeb; G Schlenstedt; David Pellman; D Kornitzer; Pamela A Silver; Gerald R Fink
The yeast nuclear import receptor is required for mitosis.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7647-51.
1995: G Schlenstedt; S Harris; B Risse; R Lill; Pamela A Silver
A yeast DnaJ homologue, Scj1p, can function in the endoplasmic reticulum with BiP/Kar2p via a conserved domain that specifies interactions with Hsp70s.
The Journal of cell biology 1995;129(4):979-88.
1995: G Schlenstedt; C Saavedra; J D Loeb; Charles N Cole; Pamela A Silver
The GTP-bound form of the yeast Ran/TC4 homologue blocks nuclear protein import and appearance of poly(A)+ RNA in the cytoplasm.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(1):225-9.
1994: J Flach; M Bossie; J Vogel; Anita H Corbett; T Jinks; D A Willins; Pamela A Silver
A yeast RNA-binding protein shuttles between the nucleus and the cytoplasm.
Molecular and cellular biology 1994;14(12):8399-407.
1994: M A Osborne; G Schlenstedt; T Jinks; Pamela A Silver
Nuf2, a spindle pole body-associated protein required for nuclear division in yeast.
The Journal of cell biology 1994;125(4):853-66.
1993: G Schlenstedt; E Hurt; Valérie Doye; Pamela A Silver
Reconstitution of nuclear protein transport with semi-intact yeast cells.
The Journal of cell biology 1993;123(4):785-98.
1993: Pamela A Silver; J C Way
Eukaryotic DnaJ homologs and the specificity of Hsp70 activity.
Cell 1993;74(1):5-6.
1993: M K Nelson; T Kurihara; Pamela A Silver
Extragenic suppressors of mutations in the cytoplasmic C terminus of SEC63 define five genes in Saccharomyces cerevisiae.
Genetics 1993;134(1):159-73.
1993: M A Osborne; Pamela A Silver
Nucleocytoplasmic transport in the yeast Saccharomyces cerevisiae.
Annual review of biochemistry 1993;62():219-54.
1993: U Stochaj; M A Bossie; K van Zee; A M Whalen; Pamela A Silver
Analysis of conserved binding proteins for nuclear localization sequences.
Journal of cell science 1993;104 ( Pt 1)():89-95.
1992: M A Bossie; Pamela A Silver
Movement of macromolecules between the cytoplasm and the nucleus in yeast.
Current opinion in genetics & development 1992;2(5):768-74.
1992: U Stochaj; Pamela A Silver
A conserved phosphoprotein that specifically binds nuclear localization sequences is involved in nuclear import.
The Journal of cell biology 1992;117(3):473-82.
1991: H Blumberg; Pamela A Silver
A homologue of the bacterial heat-shock gene DnaJ that alters protein sorting in yeast.
Nature 1991;349(6310):627-30.
1991: Pamela A Silver
How proteins enter the nucleus.
Cell 1991;64(3):489-97.
1988: Pamela A Silver; A Chiang; I Sadler
Mutations that alter both localization and production of a yeast nuclear protein.
Genes & development 1988;2(6):707-17.