FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Phyllis Silver

Research Profile

Disorders

Chemicals & Drugs

Living Beings

Physiology

Lymphocyte Activation

Anatomy

Co-author Network

Publications

TOP 3
Ru Zhou; Jun Chen; Wai Po Chong; Reiko Horai; Mary J Mattapallil; Rachael C Rigden; Phyllis B Silver; Rafael Villasmil; Carlos R Zárate-Bladés; Rachel R Caspi
The living eye "disarms" uncommitted autoreactive T cells by converting them to Foxp3(+) regulatory cells following local antigen recognition.
Rajeev K Agarwal; Phyllis B Silver; Rachel R Caspi
Rodent models of experimental autoimmune uveitis.
Sara Bar-Yehuda; Rachel R Caspi; Shira Cohen; Dror Luger; Avivit Ochaion; Renana Patokaa; Phyllis B Silver; Galina Zozulya; Jose Maria Garcia Ruiz de Morales; Pnina Fishman
Inhibition of experimental auto-immune uveitis by the A3 adenosine receptor agonist CF101.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Phyllis Silver (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2012: Ru Zhou; Jun Chen; Wai Po Chong; Reiko Horai; Mary J Mattapallil; Rachael C Rigden; Phyllis B Silver; Rafael Villasmil; Carlos R Zárate-Bladés; Rachel R Caspi
The living eye "disarms" uncommitted autoreactive T cells by converting them to Foxp3(+) regulatory cells following local antigen recognition.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(4):1742-50.
2012: Rajeev K Agarwal; Phyllis B Silver; Rachel R Caspi
Rodent models of experimental autoimmune uveitis.
Methods in molecular biology (Clifton, N.J.) 2012;900():443-69.
2011: Sara Bar-Yehuda; Rachel R Caspi; Shira Cohen; Dror Luger; Avivit Ochaion; Renana Patokaa; Phyllis B Silver; Galina Zozulya; Jose Maria Garcia Ruiz de Morales; Pnina Fishman
Inhibition of experimental auto-immune uveitis by the A3 adenosine receptor agonist CF101.
International journal of molecular medicine 2011;28(5):727-31.
2011: Mary J Mattapallil; J Hugh McDowell; Robert B Nussenblatt; H Nida Sen; Phyllis B Silver; Chi-Chao Chan; Chella S David; Reiko Horai; Eddie A James; Zaruhi Karabekian; William W Kwok; Joseph J Mattapallil; Rachel R Caspi
Uveitis-associated epitopes of retinal antigens are pathogenic in the humanized mouse model of uveitis and identify autoaggressive T cells.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(4):1977-85.
2009: Jun Tang; Ru Zhou; Dror Luger; Wei Zhu; Phyllis B Silver; Rafael S Grajewski; Shao-Bo Su; Chi-Chao Chan; Luciano Adorini; Rachel R Caspi
Calcitriol suppresses antiretinal autoimmunity through inhibitory effects on the Th17 effector response.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):4624-32.
2008: Rafael S Grajewski; Anna M Hansen; Rajeev K Agarwal; Mitchell Kronenberg; Stephane Sidobre; Shao-Bo Su; Phyllis B Silver; Moriya Tsuji; Richard W Franck; Anne P Lawton; Chi-Chao Chan; Rachel R Caspi
Activation of invariant NKT cells ameliorates experimental ocular autoimmunity by a mechanism involving innate IFN-gamma production and dampening of the adaptive Th1 and Th17 responses.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(7):4791-7.
2008: Lizette M Cortes; Dody Avichezer; Phyllis B Silver; Dror Luger; Mary J Mattapallil; Chi-Chao Chan; Rachel R Caspi
Inhibitory peptide analogs derived from a major uveitogenic epitope protect from antiretinal autoimmunity by inducing type 2 and regulatory T cells.
Journal of leukocyte biology 2008;84(2):577-85.
2008: Mary J Mattapallil; Azize Sahin; Phyllis B Silver; Shu-Hui Sun; Chi-Chao Chan; Elaine F Remmers; J Fielding Hejtmancik; Rachel R Caspi
Common genetic determinants of uveitis shared with other autoimmune disorders.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(10):6751-9.
2008: Lizette M Cortes; Mary J Mattapallil; Phyllis B Silver; Larry A Donoso; Gregory I Liou; Wei Zhu; Chi-Chao Chan; Rachel R Caspi
Repertoire analysis and new pathogenic epitopes of IRBP in C57BL/6 (H-2b) and B10.RIII (H-2r) mice.
Investigative ophthalmology & visual science 2008;49(5):1946-56.
2008: Rajeev K Agarwal; Reiko Horai; Angelia M Viley; Phyllis B Silver; Rafael S Grajewski; Shao-Bo Su; Arrash T Yazdani; Wei Zhu; Mitchell Kronenberg; Peter J Murray; Robert L Rutschman; Chi-Chao Chan; Rachel R Caspi
Abrogation of anti-retinal autoimmunity in IL-10 transgenic mice due to reduced T cell priming and inhibition of disease effector mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(8):5423-9.
2008: Dror Luger; Phyllis B Silver; Jun Tang; Daniel Cua; Zoe Chen; Yoichiro Iwakura; Edward P Bowman; Nicole M Sgambellone; Chi-Chao Chan; Rachel R Caspi
Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category.
The Journal of experimental medicine 2008;205(4):799-810.
2008: Rachel R Caspi; Phyllis B Silver; Dror Luger; Jun Tang; Lizette M Cortes; Giuseppina Pennesi; Mary J Mattapallil; Chi-Chao Chan
Mouse models of experimental autoimmune uveitis.
Ophthalmic research 2008;40(3-4):169-74.
2007: Phyllis B Silver; Rajeev K Agarwal; Shao-Bo Su; Isabelle Suffia; Rafael S Grajewski; Dror Luger; Chi-Chao Chan; Rashid M Mahdi; John M Nickerson; Rachel R Caspi
Hydrodynamic vaccination with DNA encoding an immunologically privileged retinal antigen protects from autoimmunity through induction of regulatory T cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(8):5146-58.
2007: Shao-Bo Su; Rafael S Grajewski; Dror Luger; Rajeev K Agarwal; Phyllis B Silver; Jun Tang; Jingsheng Tuo; Chi-Chao Chan; Rachel R Caspi
Altered chemokine profile associated with exacerbated autoimmune pathology under conditions of genetic interferon-gamma deficiency.
Investigative ophthalmology & visual science 2007;48(10):4616-25.
2007: Jun Tang; Wei Zhu; Phyllis B Silver; Shao-Bo Su; Chi-Chao Chan; Rachel R Caspi
Autoimmune uveitis elicited with antigen-pulsed dendritic cells has a distinct clinical signature and is driven by unique effector mechanisms: initial encounter with autoantigen defines disease phenotype.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5578-87.
2006: Rafael S Grajewski; Phyllis B Silver; Rajeev K Agarwal; Shao-Bo Su; Chi-Chao Chan; Gregory I Liou; Rachel R Caspi
Endogenous IRBP can be dispensable for generation of natural CD4+CD25+ regulatory T cells that protect from IRBP-induced retinal autoimmunity.
The Journal of experimental medicine 2006;203(4):851-6.
2005: Shao-Bo Su; Phyllis B Silver; Rafael S Grajewski; Rajeev K Agarwal; Jun Tang; Chi-Chao Chan; Rachel R Caspi
Essential role of the MyD88 pathway, but nonessential roles of TLRs 2, 4, and 9, in the adjuvant effect promoting Th1-mediated autoimmunity.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(10):6303-10.
2005: Zaruhi Karabekian; Simon D Lytton; Phyllis B Silver; Yuri V Sergeev; Jonathan P Schneck; Rachel R Caspi
Antigen/MHC class II/Ig dimers for study of uveitogenic T cells: IRBP p161-180 presented by both IA and IE molecules.
Investigative ophthalmology & visual science 2005;46(10):3769-76.
2005: Lee Bagenstose; Rajeev K Agarwal; Phyllis B Silver; David M Harlan; Steven C Hoffmann; Robert L Kampen; Chi-Chao Chan; Rachel R Caspi
Disruption of CD40/CD40-ligand interactions in a retinal autoimmunity model results in protection without tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(1):124-30.
2004: Shao-Bo Su; Phyllis B Silver; Peng Wang; Chi-Chao Chan; Rachel R Caspi
Cholera toxin prevents Th1-mediated autoimmune disease by inducing immune deviation.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):755-61.
2003: Dody Avichezer; Rafael S Grajewski; Chi-Chao Chan; Mary J Mattapallil; Phyllis B Silver; James A Raber; Gregory I Liou; Barbara Wiggert; Giavonni M Lewis; Larry A Donoso; Rachel R Caspi
An immunologically privileged retinal antigen elicits tolerance: major role for central selection mechanisms.
The Journal of experimental medicine 2003;198(11):1665-76.
2003: Hui Xu; Phyllis B Silver; Teresa Tarrant; Chi-Chao Chan; Rachel R Caspi
Tgf-beta inhibits activation and uveitogenicity of primary but not of fully polarized retinal antigen-specific memory-effector T cells.
Investigative ophthalmology & visual science 2003;44(11):4805-12.
2003: Shao-Bo Su; Phyllis B Silver; Peng Wang; Chi-Chao Chan; Rachel R Caspi
Dissociating the enhancing and inhibitory effects of pertussis toxin on autoimmune disease.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2314-9.
2003: Giuseppina Pennesi; Mary J Mattapallil; Shu-Hui Sun; Dody Avichezer; Phyllis B Silver; Zaruhi Karabekian; Chella S David; Paul A Hargrave; J Hugh McDowell; W Clay Smith; Barbara Wiggert; Larry A Donoso; Chi-Chao Chan; Rachel R Caspi
A humanized model of experimental autoimmune uveitis in HLA class II transgenic mice.
The Journal of clinical investigation 2003;111(8):1171-80.
2003: Peng Wang; Shu-Hui Sun; Phyllis B Silver; Chi-Chao Chan; Rajeev K Agarwal; Barbara Wiggert; Leonard D Kohn; Gordon A Jamieson; Rachel R Caspi
Methimazole protects from experimental autoimmune uveitis (EAU) by inhibiting antigen presenting cell function and reducing antigen priming.
Journal of leukocyte biology 2003;73(1):57-64.
2001: Shao-Bo Su; Phyllis B Silver; Meifen Zhang; Chi-Chao Chan; Rachel R Caspi
Pertussis toxin inhibits induction of tissue-specific autoimmune disease by disrupting G protein-coupled signals.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(1):250-6.
2000: Phyllis B Silver; Karen S Hathcock; Chi-Chao Chan; Barbara Wiggert; Rachel R Caspi
Blockade of costimulation through B7/CD28 inhibits experimental autoimmune uveoretinitis, but does not induce long-term tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(9):5041-7.
2000: Dody Avichezer; Chi-Chao Chan; Phyllis B Silver; Barbara Wiggert; Rachel R Caspi
Residues 1-20 of IRBP and whole IRBP elicit different uveitogenic and immunological responses in interferon gamma deficient mice.
Experimental eye research 2000;71(2):111-8.
2000: MT Magone; Scott M Whitcup; A Fukushima; Chi-Chao Chan; Phyllis B Silver; Luiz Vicente Rizzo
The role of IL-12 in the induction of late-phase cellular infiltration in a murine model of allergic conjunctivitis.
The Journal of allergy and clinical immunology 2000;105(2 Pt 1):299-308.
2000: Dody Avichezer; Phyllis B Silver; Chi-Chao Chan; Barbara Wiggert; Rachel R Caspi
Identification of a new epitope of human IRBP that induces autoimmune uveoretinitis in mice of the H-2b haplotype.
Investigative ophthalmology & visual science 2000;41(1):127-31.
1999: Phyllis B Silver; Chi-Chao Chan; Barbara Wiggert; Rachel R Caspi
The requirement for pertussis to induce EAU is strain-dependent: B10.RIII, but not B10.A mice, develop EAU and Th1 responses to IRBP without pertussis treatment.
Investigative ophthalmology & visual science 1999;40(12):2898-905.
1999: Ronald L Wilder; Marie M Griffiths; Elaine F Remmers; Grant W Cannon; Rachel R Caspi; Yutaka Kawahito; Pércio S Gulko; RE Longman; Svetlana Dracheva; Y Du; S H Sun; JianPing Wang; JS Shepard; bina joe; Lynn Ge; S Chen; L Chang; J Hoffman; Phyllis B Silver; Van Reese
Localization in rats of genetic loci regulating susceptibility to experimental erosive arthritis and related autoimmune diseases.
Transplantation proceedings 1999;31(3):1585-8.
1999: Phyllis B Silver; Teresa Tarrant; Chi-Chao Chan; Barbara Wiggert; Rachel R Caspi
Mice deficient in inducible nitric oxide synthase are susceptible to experimental autoimmune uveoretinitis.
Investigative ophthalmology & visual science 1999;40(6):1280-4.
1999: Shu-Hui Sun; Phyllis B Silver; Rachel R Caspi; Y Du; Chi-Chao Chan; Ronald L Wilder; Elaine F Remmers
Identification of genomic regions controlling experimental autoimmune uveoretinitis in rats.
International immunology 1999;11(4):529-34.
1999: Hui Xu; G Strassmann; Chi-Chao Chan; Luiz Vicente Rizzo; Phyllis B Silver; Barbara Wiggert; Rachel R Caspi
Protective effect of the type IV phosphodiesterase inhibitor rolipram in EAU: protection is independent of IL-10-inducing activity.
Investigative ophthalmology & visual science 1999;40(5):942-50.
1999: Teresa Tarrant; Phyllis B Silver; J L Wahlsten; Luiz Vicente Rizzo; Chi-Chao Chan; Barbara Wiggert; Rachel R Caspi
Interleukin 12 protects from a T helper type 1-mediated autoimmune disease, experimental autoimmune uveitis, through a mechanism involving interferon gamma, nitric oxide, and apoptosis.
The Journal of experimental medicine 1999;189(2):219-30.
1998: S Savion; Phyllis B Silver; Chi-Chao Chan; Rachel R Caspi
Acute immunosuppression and syngeneic bone marrow transplantation in ocular autoimmunity abort disease, but do not result in induction of long-term protection.
Ocular immunology and inflammation 1998;6(3):163-72.
1998: Phyllis B Silver; Luiz Vicente Rizzo; Bing Sun; Chi-Chao Chan; Barbara Wiggert; Robert B Nussenblatt; Rachel R Caspi
Heterologous epitopes of IRBP protect against autoimmune uveitis induced by the autologous epitope.
Journal of neuroimmunology 1998;88(1-2):128-36.
1998: Teresa Tarrant; Phyllis B Silver; Chi-Chao Chan; Barbara Wiggert; Rachel R Caspi
Endogenous IL-12 is required for induction and expression of experimental autoimmune uveitis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):122-7.
1997: Hui Xu; Luiz Vicente Rizzo; Phyllis B Silver; Rachel R Caspi
Uveitogenicity is associated with a Th1-like lymphokine profile: cytokine-dependent modulation of early and committed effector T cells in experimental autoimmune uveitis.
Cellular immunology 1997;178(1):69-78.
1997: Rachel R Caspi; Bing Sun; Rajeev K Agarwal; Phyllis B Silver; Luiz Vicente Rizzo; Chi-Chao Chan; Barbara Wiggert; Ronald L Wilder
T cell mechanisms in experimental autoimmune uveoretinitis: susceptibility is a function of the cytokine response profile.
Eye (London, England) 1997;11 ( Pt 2)():209-12.
1996: G Sartani; Phyllis B Silver; Luiz Vicente Rizzo; Chi-Chao Chan; Barbara Wiggert; George Mastorakos; Rachel R Caspi
Anti-tumor necrosis factor alpha therapy suppresses the induction of experimental autoimmune uveoretinitis in mice by inhibiting antigen priming.
Investigative ophthalmology & visual science 1996;37(11):2211-8.
1996: Rachel R Caspi; Phyllis B Silver; Chi-Chao Chan; Bing Sun; Rajeev K Agarwal; J Wells; S Oddo; Y Fujino; F Najafian; Ronald L Wilder
Genetic susceptibility to experimental autoimmune uveoretinitis in the rat is associated with an elevated Th1 response.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(6):2668-75.
1995: G Sartani; Phyllis B Silver; G Strassmann; Chi-Chao Chan; Rachel R Caspi
Suramin treatment suppresses induction of experimental autoimmune uveoretinitis (EAU) in rodents.
Current eye research 1995;14(10):887-96.
1995: George Mastorakos; Evrydiki A Bouzas; Phyllis B Silver; G Sartani; T C Friedman; Chi-Chao Chan; Rachel R Caspi; George Chrousos
Immune corticotropin-releasing hormone is present in the eyes of and promotes experimental autoimmune uveoretinitis in rodents.
Endocrinology 1995;136(10):4650-8.
1995: Phyllis B Silver; Luiz Vicente Rizzo; Chi-Chao Chan; L A Donoso; Barbara Wiggert; Rachel R Caspi
Identification of a major pathogenic epitope in the human IRBP molecule recognized by mice of the H-2r haplotype.
Investigative ophthalmology & visual science 1995;36(5):946-54.
1994: Rachel R Caspi; Chi-Chao Chan; B G Grubbs; Phyllis B Silver; Barbara Wiggert; Cameron F Parsa; S Bahmanyar; A Billiau; H Heremans
Endogenous systemic IFN-gamma has a protective role against ocular autoimmunity in mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(2):890-9.