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Edwin Silverman

Research Profile

Disorders

Genes & Molecular Sequences

Single Nucleotide Polymorphism

Physiology

Activities & Behaviors

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Publications

TOP 3
Mateusz Siedlinski; Edwin K Silverman; David Sparrow; Dustin Tingley; Wayne Anderson; Per Bakke; Terri H beaty; Michael H Cho; James D Crapo; Amund Gulsvik; John E Hokanson; Xiangyang Kong; Christoph Lange; Peter J Lipman; Augusto A Litonjua; David A Lomas; Stephen I Rennard
Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.
Alejandro A Diaz; Mark T Dransfield; Meilan K Han; Victor Kim; David A Lynch; James C Ross; Raúl San José-Estépar; Joyce D Schroeder; Edwin K Silverman; Juerg Tschirren; Carolyn E Come; Douglas Curran-Everett; George R Washko
Effect of emphysema on CT scan measures of airway dimensions in smokers.
Craig Hersh; John E Hokanson; Philip F Judy; Sharon Lutz; David A Lynch; Barry J Make; Nathaniel Marchetti; John D Newell; Frank C Sciurba; Edwin K Silverman; George R Washko; James D Crapo; Raúl San José Estépar; Paul J Friedman; Meilan K Han
Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD.

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All Publications

2013: Mateusz Siedlinski; Edwin K Silverman; David Sparrow; Dustin Tingley; Wayne Anderson; Per Bakke; Terri H beaty; Michael H Cho; James D Crapo; Amund Gulsvik; John E Hokanson; Xiangyang Kong; Christoph Lange; Peter J Lipman; Augusto A Litonjua; David A Lomas; Stephen I Rennard
Dissecting direct and indirect genetic effects on chronic obstructive pulmonary disease (COPD) susceptibility.
Human genetics 2013;132(4):431-41.
2013: Alejandro A Diaz; Mark T Dransfield; Meilan K Han; Victor Kim; David A Lynch; James C Ross; Raúl San José-Estépar; Joyce D Schroeder; Edwin K Silverman; Juerg Tschirren; Carolyn E Come; Douglas Curran-Everett; George R Washko
Effect of emphysema on CT scan measures of airway dimensions in smokers.
Chest 2013;143(3):687-93.
2013: Craig Hersh; John E Hokanson; Philip F Judy; Sharon Lutz; David A Lynch; Barry J Make; Nathaniel Marchetti; John D Newell; Frank C Sciurba; Edwin K Silverman; George R Washko; James D Crapo; Raúl San José Estépar; Paul J Friedman; Meilan K Han
Paired inspiratory-expiratory chest CT scans to assess for small airways disease in COPD.
Respiratory research 2013;14():42.
2012: Deog Kyeom Kim; Xiangyang Kong; Augusto A Litonjua; David A Lomas; William MacNee; Bruce E Miller; Weiliang Qiu; Stephen Rennard; John H Riley; Edwin K Silverman; Ruth Tal-Singer; Jørgen Vestbo; Emiel Wouters; Julie C Yates; Alvar Agustí; Per Bakke; Terri H beaty; Bartolome Celli; Michael H Cho; Harvey O Coxson; James D Crapo; Amund Gulsvik; Craig Hersh
Genome-wide association analysis of blood biomarkers in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2012;186(12):1238-47.
2012: Heide Fier; Rolf Fimmers; Taofik AlChawa; Kerstin U Ludwig; Elisabeth Mangold; Marcello Pagano; Dmitry Prokopenko; Edwin K Silverman; Sungho Won; Christoph Lange
'Location, Location, Location': a spatial approach for rare variant analysis and an application to a study on non-syndromic cleft lip with or without cleft palate.
Bioinformatics (Oxford, England) 2012;28(23):3027-33.
2012: Megan Hardin; Iwona Hawrylkiewicz; Craig Hersh; Eric Schwinder; Peter J Castaldi; Michael H Cho; Pawel Sliwinski; Emily S Wan; Jan Zielinski; Edwin K Silverman
CHRNA3/5, IREB2, and ADCY2 are associated with severe chronic obstructive pulmonary disease in Poland.
American journal of respiratory cell and molecular biology 2012;47(2):203-8.
2012: Tracy J Doyle; Isis E Fernandez; Hiroto Hatabu; Gary M Hunninghake; Mizuki Nishino; Yuka Okajima; Ivan O Rosas; Frank C Sciurba; Edwin K Silverman; George R Washko; Tsuneo Yamashiro; Bartolome R Celli; Miguel J Divo
Interstitial lung abnormalities and reduced exercise capacity.
American journal of respiratory and critical care medicine 2012;185(7):756-62.
2012: Jin-Fu Xu; Tsuneo Yamashiro; Raúl San José-Estépar; Augustine M K Choi; Carolyn E Come; James D Crapo; Katherine D'Aco; Alejandro A Diaz; Isis E Fernandez; Meilan K Han; Hiroto Hatabu; Blanca E Himes; Gary M Hunninghake; Hui-Ping Li; David A Lynch; Fernando J Martinez; Danielle Morse; Kiichi Nakahira; Mizuki Nishino; Yuka Okajima; Avignat S Patel; Jie-Ming Qu; Ivan O Rosas; James C Ross; Stefan W Ryter; Edwin K Silverman; George R Washko
Statins and pulmonary fibrosis: the potential role of NLRP3 inflammasome activation.
American journal of respiratory and critical care medicine 2012;185(5):547-56.
2012: Alejandro A Diaz; Meilan K Han; Stephen H Loring; James C Ross; Raúl San José-Estépar; Edwin K Silverman; George R Washko; Carolyn E Come
Association between airway caliber changes with lung inflation and emphysema assessed by volumetric CT scan in subjects with COPD.
Chest 2012;141(3):736-44.
2012: Woo Jin Kim; Gerard McElvaney; Stephen I Rennard; Robert A Sandhaus; Edwin K Silverman; Robert A Stockley; James M Stocks; James K Stoller; Charlie Strange; Gerard M Turino; Alice M Wood; Alan Freund Barker; Mark L Brantly; Edward J Campbell; Edward Eden; Dawn L DeMeo
Association of IREB2 and CHRNA3 polymorphisms with airflow obstruction in severe alpha-1 antitrypsin deficiency.
Respiratory research 2012;13():16.
2011: John M Brehm; Shannon Bruse; Wayne H Anderson; Lydiana Avila; Per Bakke; Soumyaroop Bhattacharya; Nadia Boutaoui; Michael H Cho; Soma Datta; Erick Forno; Amund Gulsvik; Koichi Hagiwara; Blanca Himes; Francine Jacobson; Augusto A Litonjua; David A Lomas; Thomas J Mariani; Edwin K Silverman; Manuel E Soto-Quiros; Yohannes Tesfaigzi; John P Ziniti; Juan C Celedón
Identification of FGF7 as a novel susceptibility locus for chronic obstructive pulmonary disease.
Thorax 2011;66(12):1085-90.
2011: Thomas J Hoffmann; Christoph Lange; Edwin K Silverman; Stijn Vansteelandt; Dawn L DeMeo; Nan M Laird
Combining disease models to test for gene-environment interaction in nuclear families.
Biometrics 2011;67(4):1260-70.
2011: Mateusz Siedlinski; Edwin K Silverman; Wayne Anderson; Per Bakke; Terri H beaty; Michael H Cho; James D Crapo; Amund Gulsvik; John E Hokanson; Xiangyang Kong; David A Lomas; Stephen I Rennard
Genome-wide association study of smoking behaviours in patients with COPD.
Thorax 2011;66(10):894-902.
2011: Jørgen Vestbo; Emiel Wouters; Julie C Yates; Alvar Agusti; Per Bakke; Peter M A Calverley; Bartolome Celli; Harvey O Coxson; Courtney Crim; Lisa D Edwards; David A Lomas; William MacNee; Bruce E Miller; Stephen I Rennard; Paul D Scanlon; Edwin K Silverman; Ruth Tal-Singer
Changes in forced expiratory volume in 1 second over time in COPD.
The New England journal of medicine 2011;365(13):1184-92.
2011: Blanca E Himes; Barbara J Klanderman; Christoph Lange; Jessica Lasky-Su; Thomas J Mariani; Benjamin A Raby; Jody Senter-Sylvia; Edwin K Silverman; Manuel E Soto-Quiros; Scott T Weiss; John Ziniti; Lydiana Avila; Juan C Celedón; Craig Hersh; Dawn L DeMeo
Association of SERPINE2 with asthma.
Chest 2011;140(3):667-74.
2011: Marilyn G Foreman; Nadia N Hansel; John E Hokanson; Barry Make; James Murphy; Elizabeth A Regan; Edwin K Silverman; George R Washko; Lening Zhang; James D Crapo; Dawn L DeMeo
Early-onset chronic obstructive pulmonary disease is associated with female sex, maternal factors, and African American race in the COPDGene Study.
American journal of respiratory and critical care medicine 2011;184(4):414-20.
2011: Deog Kyeom Kim; Barry J Make; Edwin K Silverman; George R Washko; Richard Casaburi; James D Crapo; Francine L Jacobson; Craig Hersh
Clinical and radiographic correlates of hypoxemia and oxygen therapy in the COPDGene study.
Respiratory medicine 2011;105(8):1211-21.
2011: Craig Hersh; John E Hokanson; David A Lynch; Barry J Make; Edwin K Silverman; George R Washko; James D Crapo
Family history is a risk factor for COPD.
Chest 2011;140(2):343-50.
2011: Emily S Wan; James D Crapo; John E Hokanson; David A Lynch; Barry J Make; James R Murphy; Elizabeth A Regan; Edwin K Silverman
Clinical and radiographic predictors of GOLD-unclassified smokers in the COPDGene study.
American journal of respiratory and critical care medicine 2011;184(1):57-63.
2011: Peter J Lipman; David A Lomas; Edwin K Silverman; Wayne Anderson; Per Bakke; Michael H Cho; Amund Gulsvik; Xiangyang Kong; Christoph Lange
On the follow-up of genome-wide association studies: an overall test for the most promising SNPs.
Genetic epidemiology 2011;35(5):303-9.
2011: Craig Hersh; Edwin K Silverman; Jody Gascon; Soumyaroop Bhattacharya; Barbara J Klanderman; Augusto A Litonjua; Véronique Lefebvre; David Sparrow; John J Reilly; Wayne H Anderson; David A Lomas; Thomas J Mariani
SOX5 is a candidate gene for chronic obstructive pulmonary disease susceptibility and is necessary for lung development.
American journal of respiratory and critical care medicine 2011;183(11):1482-9.
2011: Don D Sin; Ruth Tal-Singer; Donald Tashkin; Robert Wise; Xuekui Zhang; Nicholas A Anthonisen; Bartolome R Celli; John E Connett; Annelyse Duvoix; Lisa D Edwards; Nicholas Locantore; David A Lomas; William MacNee; S F Paul Man; Bruce E Miller; Edwin K Silverman
Serum PARC/CCL-18 concentrations and health outcomes in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2011;183(9):1187-92.
2011: George R Washko; Gary M Hunninghake; Isis E Fernandez; Mizuki Nishino; Yuka Okajima; Tsuneo Yamashiro; James C Ross; Raúl San José Estépar; David A Lynch; John M Brehm; Katherine P Andriole; Alejandro A Diaz; Ramin Khorasani; Katherine D'Aco; Frank C Sciurba; Edwin K Silverman; Hiroto Hatabu; Ivan O Rosas
Lung volumes and emphysema in smokers with interstitial lung abnormalities.
The New England journal of medicine 2011;364(10):897-906.
2011: Tsuneo Yamashiro; Raúl San José-Estépar; Shin Matsuoka; Brian J Bartholmai; James C Ross; Alejandro Diaz; Sadayuki Murayama; Edwin K Silverman; Hiroto Hatabu; George R Washko
Intrathoracic tracheal volume and collapsibility on inspiratory and end-expiratory ct scans correlations with lung volume and pulmonary function in 85 smokers.
Academic radiology 2011;18(3):299-305.
2011: Marilyn G Foreman; Xiangyang Kong; Dawn L DeMeo; Sreekumar G Pillai; Craig P Hersh; Per Bakke; Amund Gulsvik; David A Lomas; Augusto A Litonjua; Steven D Shapiro; Ruth Tal-Singer; Edwin K Silverman
Polymorphisms in surfactant protein-D are associated with chronic obstructive pulmonary disease.
American journal of respiratory cell and molecular biology 2011;44(3):316-22.
2011: Tsuneo Yamashiro; Shin Matsuoka; Raúl San José Estépar; Brian J Bartholmai; Alejandro Diaz; James C Ross; Sadayuki Murayama; Edwin K Silverman; Hiroto Hatabu; George R Washko
Kurtosis and skewness of density histograms on inspiratory and expiratory CT scans in smokers.
COPD 2011;8(1):13-20.
2011: Megan Hardin; Craig Hersh; Barry J Make; Joyce D Schroeder; Edwin K Silverman; R Graham Barr; James D Crapo; Nadia N Hansel
The clinical features of the overlap between COPD and asthma.
Respiratory research 2011;12():127.
2011: Weiliang Qiu; Stephen Rennard; John H Riley; Edwin K Silverman; Dave Singh; Ruth Tal-Singer; Wayne H Anderson; Per Bakke; Terri H beaty; Bartolome R Celli; Michael H Cho; James D Crapo; Steven M Fox; Amund Gulsvik; Craig Hersh; Augusto A Litonjua; David A Lomas
Genetics of sputum gene expression in chronic obstructive pulmonary disease.
PloS one 2011;6(9):e24395.
2011: Soumyaroop Bhattacharya; Raphael Bueno; Dawn L DeMeo; John J Reilly; Steven D Shapiro; Edwin K Silverman; Sorachai Srisuma; Shivraj Tyagi; Thomas J Mariani
Peripheral blood gene expression profiles in COPD subjects.
Journal of clinical bioinformatics 2011;1(1):12.
2011: Deog Kyeom Kim; Craig Hersh; George R Washko; John E Hokanson; David A Lynch; John D Newell; James R Murphy; James D Crapo; Edwin K Silverman
Epidemiology, radiology, and genetics of nicotine dependence in COPD.
Respiratory research 2011;12():9.
2011: Shin Matsuoka; Tsuneo Yamashiro; Alejandro Diaz; Raúl San José Estépar; James C Ross; Edwin K Silverman; Yasuyuki Kobayashi; Mark T Dransfield; Brian J Bartholmai; Hiroto Hatabu; George R Washko
The relationship between small pulmonary vascular alteration and aortic atherosclerosis in chronic obstructive pulmonary disease: quantitative CT analysis.
Academic radiology 2011;18(1):40-6.
2011: Woo Jin Kim; E Hoffman; John Reilly; Craig Hersh; Dawn L DeMeo; George R Washko; Edwin K Silverman
Association of COPD candidate genes with computed tomography emphysema and airway phenotypes in severe COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2011;37(1):39-43.
2010: Truls Ingebrigtsen; Simon F Thomsen; Jørgen Vestbo; Sophie van der Sluis; Kirsten O Kyvik; Edwin K Silverman; Magnus Svartengren; Vibeke Backer
Genetic influences on Chronic Obstructive Pulmonary Disease - a twin study.
Respiratory medicine 2010;104(12):1890-5.
2010: Alejandro A Diaz; Clarissa Valim; Tsuneo Yamashiro; Raúl San José Estépar; James C Ross; Shin Matsuoka; Brian J Bartholmai; Hiroto Hatabu; Edwin K Silverman; George R Washko
Airway count and emphysema assessed by chest CT imaging predicts clinical outcome in smokers.
Chest 2010;138(4):880-7.
2010: Craig Hersh; Sreekumar G Pillai; Guohua Zhu; David A Lomas; Per Bakke; Amund Gulsvik; Dawn L DeMeo; Barbara J Klanderman; Ross Lazarus; Augusto A Litonjua; David Sparrow; John J Reilly; Alvar Agusti; Peter M A Calverley; Claudio F Donner; Robert D Levy; Barry Make; Peter D Paré; Stephen I Rennard; Jørgen Vestbo; Emiel F M Wouters; Mary Beth Scholand; Hilary Coon; John Hoidal; Edwin K Silverman
Multistudy fine mapping of chromosome 2q identifies XRCC5 as a chronic obstructive pulmonary disease susceptibility gene.
American journal of respiratory and critical care medicine 2010;182(5):605-13.
2010: I C Sørheim; Dawn L DeMeo; George R Washko; Augusto A Litonjua; David Sparrow; R Bowler; P Bakke; S G Pillai; H O Coxson; D A Lomas; Edwin K Silverman; Craig Hersh
Polymorphisms in the superoxide dismutase-3 gene are associated with emphysema in COPD.
COPD 2010;7(4):262-8.
2010: Tsuneo Yamashiro; Shin Matsuoka; Raúl San José Estépar; Mark T Dransfield; Alejandro Diaz; John J Reilly; Samuel Patz; Sadayuki Murayama; Edwin K Silverman; Hiroto Hatabu; George R Washko
Quantitative assessment of bronchial wall attenuation with thin-section CT: An indicator of airflow limitation in chronic obstructive pulmonary disease.
AJR. American journal of roentgenology 2010;195(2):363-9.
2010: Alejandro A Diaz; Brian Bartholmai; Raúl San José-Estépar; James Ross; Shin Matsuoka; Tsuneo Yamashiro; Hiroto Hatabu; John J Reilly; Edwin K Silverman; George R Washko
Relationship of emphysema and airway disease assessed by CT to exercise capacity in COPD.
Respiratory medicine 2010;104(8):1145-51.
2010: Inga-Cecilie Sørheim; Ane Johannessen; Amund Gulsvik; Per S Bakke; Edwin K Silverman; Dawn L DeMeo
Gender differences in COPD: are women more susceptible to smoking effects than men?
Thorax 2010;65(6):480-5.
2010: Tsuneo Yamashiro; Shin Matsuoka; Brian J Bartholmai; Raúl San José-Estépar; James C Ross; Alejandro Diaz; Sadayuki Murayama; Edwin K Silverman; Hiroto Hatabu; George R Washko
Collapsibility of lung volume by paired inspiratory and expiratory CT scans: correlations with lung function and mean lung density.
Academic radiology 2010;17(4):489-95.
2010: Emily S Wan; Barbara R Pober; George R Washko; Benjamin A Raby; Edwin K Silverman
Pulmonary function and emphysema in Williams-Beuren syndrome.
American journal of medical genetics. Part A 2010;152A(3):653-6.
2010: Michael H Cho; Nadia Boutaoui; Barbara J Klanderman; Jody S Sylvia; John P Ziniti; Craig P Hersh; Dawn L DeMeo; Gary M Hunninghake; Augusto A Litonjua; David Sparrow; Christoph Lange; Sungho Won; James R Murphy; Terri H beaty; Elizabeth A Regan; Barry J Make; John E Hokanson; James D Crapo; Xiangyang Kong; Wayne H Anderson; Ruth Tal-Singer; David A Lomas; Per Bakke; Amund Gulsvik; Sreekumar G Pillai; Edwin K Silverman
Variants in FAM13A are associated with chronic obstructive pulmonary disease.
Nature genetics 2010;42(3):200-2.
2010: George R Washko; Fernando J Martinez; Eric A Hoffman; Stephen H Loring; Raúl San José Estépar; Alejandro A Diaz; Frank C Sciurba; Edwin K Silverman; Meilan K Han; Malcolm M DeCamp; John J Reilly
Physiological and computed tomographic predictors of outcome from lung volume reduction surgery.
American journal of respiratory and critical care medicine 2010;181(5):494-500.
2010: Shin Matsuoka; George R Washko; Tsuneo Yamashiro; Raul San Jose Estepar; Alejandro Diaz; Edwin K Silverman; Eric Hoffman; Henry E Fessler; Gerard J Criner; Nathaniel Marchetti; Steven M Scharf; Fernando J Martinez; John J Reilly; Hiroto Hatabu
Pulmonary hypertension and computed tomography measurement of small pulmonary vessels in severe emphysema.
American journal of respiratory and critical care medicine 2010;181(3):218-25.
2010: James C Ross; Raúl San José-Estépar; Gordon Kindlmann; Alejandro Díaz; Carl-Fredrik Westin; Edwin K Silverman; George R Washko
Automatic lung lobe segmentation using particles, thin plate splines, and maximum a posteriori estimation.
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 2010;13(Pt 3):163-71.
2010: Alvar Agusti; Peter M A Calverley; Bartolome Celli; Harvey O Coxson; Lisa D Edwards; David A Lomas; William MacNee; Bruce E Miller; Steve Rennard; Edwin K Silverman; Ruth Tal-Singer; Emiel Wouters; Julie C Yates; Jørgen Vestbo
Characterisation of COPD heterogeneity in the ECLIPSE cohort.
Respiratory research 2010;11():122.
2010: Blanca E Himes; Jessica Lasky-Su; Ann C Wu; Jemma B Wilk; Gary M Hunninghake; Barbara Klanderman; Amy J Murphy; Ross Lazarus; Manuel E Soto-Quiros; Lydiana Avila; Juan C Celedón; Christoph Lange; George T O'Connor; Benjamin A Raby; Edwin K Silverman; Scott T Weiss
Asthma-susceptibility variants identified using probands in case-control and family-based analyses.
BMC medical genetics 2010;11():122.
2010: Michael H Cho; George R Washko; Thomas J Hoffmann; Gerard J Criner; Eric A Hoffman; Fernando J Martinez; Nan Laird; John J Reilly; Edwin K Silverman
Cluster analysis in severe emphysema subjects using phenotype and genotype data: an exploratory investigation.
Respiratory research 2010;11():30.
2010: Angela J Rogers; Benjamin A Raby; John Lima; Jessica Lasky-Su; Amy Murphy; Ross Lazarus; Barbara J Klanderman; Jody S Sylvia; John P Ziniti; Christoph Lange; Juan C Celedón; Edwin K Silverman; Scott T Weiss
Stronger evidence for replication of NPPA using genome-wide genotyping data.
American journal of respiratory and critical care medicine 2010;181(1):96.
2010: Thomas J Hoffmann; Christoph Lange; Stijn Vansteelandt; Benjamin A Raby; Dawn L DeMeo; Edwin K Silverman; Scott T Weiss; Nan M Laird
Parsing the effects of individual SNPs in candidate genes with family data.
Human heredity 2010;69(2):91-103.
2010: George R Washko; David A Lynch; Shin Matsuoka; James C Ross; Shigeaki Umeoka; Alejandro Diaz; Frank C Sciurba; Gary M Hunninghake; Raúl San José-Estépar; Edwin K Silverman; Ivan O Rosas; Hiroto Hatabu
Identification of early interstitial lung disease in smokers from the COPDGene Study.
Academic radiology 2010;17(1):48-53.
2009: Gary M Hunninghake; Michael H Cho; Yohannes Tesfaigzi; Manuel E Soto-Quiros; Lydiana Avila; Jessica Lasky-Su; Chris Stidley; Erik Melén; Cilla Söderhäll; Jenny Hallberg; Inger Kull; Juha Kere; Magnus Svartengren; Göran Pershagen; Magnus Wickman; Christoph Lange; Dawn L DeMeo; Craig Hersh; Barbara J Klanderman; Benjamin A Raby; David Sparrow; Steven D Shapiro; Edwin K Silverman; Augusto A Litonjua; Scott T Weiss; Juan C Celedón
MMP12, lung function, and COPD in high-risk populations.
The New England journal of medicine 2009;361(27):2599-608.
2009: Tsuneo Yamashiro; Shin Matsuoka; Raúl San José Estépar; Alejandro Diaz; John D Newell; Robert A Sandhaus; Patricia J Mergo; Mark L Brantly; Sadayuki Murayama; John Reilly; Hiroto Hatabu; Edwin K Silverman; George R Washko
Quantitative airway assessment on computed tomography in patients with alpha1-antitrypsin deficiency.
COPD 2009;6(6):468-77.
2009: Dawn L DeMeo; Thomas J Mariani; Soumyaroop Bhattacharya; Sorachai Srisuma; Christoph Lange; Augusto A Litonjua; Raphael Bueno; Sreekumar G Pillai; David A Lomas; David Sparrow; Steven D Shapiro; Gerard J Criner; hong pyo kim; Zhihua Chen; Augustine M K Choi; John Reilly; Edwin K Silverman
Integration of genomic and genetic approaches implicates IREB2 as a COPD susceptibility gene.
American journal of human genetics 2009;85(4):493-502.
2009: Craig Hersh; Nadia N Hansel; Kathleen C Barnes; David A Lomas; Sreekumar G Pillai; Harvey O Coxson; Rasika A Mathias; Nicholas M Rafaels; Robert Wise; John E Connett; Barbara J Klanderman; Francine L Jacobson; Ritu Gill; Augusto A Litonjua; David Sparrow; John Reilly; Edwin K Silverman
Transforming growth factor-beta receptor-3 is associated with pulmonary emphysema.
American journal of respiratory cell and molecular biology 2009;41(3):324-31.
2009: Woo Jin Kim; Edwin K Silverman; Eric Hoffman; Gerard J Criner; Zab Mosenifar; Frank C Sciurba; Barry Make; Vincent Carey; Raúl San José Estépar; Alejandro Diaz; John J Reilly; Fernando J Martinez; George R Washko
CT metrics of airway disease and emphysema in severe COPD.
Chest 2009;136(2):396-404.
2009: George R Washko; Mark T Dransfield; Raúl San José Estépar; Alejandro Diaz; Shin Matsuoka; Tsuneo Yamashiro; Hiroto Hatabu; Edwin K Silverman; William C Bailey; John Reilly
Airway wall attenuation: a biomarker of airway disease in subjects with COPD.
Journal of applied physiology (Bethesda, Md. : 1985) 2009;107(1):185-91.
2009: Edwin K Silverman; Robert A Sandhaus
Clinical practice. Alpha1-antitrypsin deficiency.
The New England journal of medicine 2009;360(26):2749-57.
2009: Angela J Rogers; Benjamin A Raby; Jessica Lasky-Su; Amy Murphy; Ross Lazarus; Barbara J Klanderman; Jody S Sylvia; John P Ziniti; Christoph Lange; Juan C Celedón; Edwin K Silverman; Scott Weiss
Assessing the reproducibility of asthma candidate gene associations, using genome-wide data.
American journal of respiratory and critical care medicine 2009;179(12):1084-90.
2009: Michael H Cho; Dawn M Ciulla; Barbara J Klanderman; Craig Hersh; Augusto A Litonjua; David Sparrow; Benjamin A Raby; Edwin K Silverman
Analysis of exonic elastin variants in severe, early-onset chronic obstructive pulmonary disease.
American journal of respiratory cell and molecular biology 2009;40(6):751-5.
2009: Blanca E Himes; Gary M Hunninghake; James W Baurley; Nicholas M Rafaels; Patrick Sleiman; David P Strachan; Jemma B Wilk; Saffron A G Willis-Owen; Barbara Klanderman; Jessica Lasky-Su; Ross Lazarus; Amy J Murphy; Manuel E Soto-Quiros; Lydiana Avila; Terri H beaty; Rasika A Mathias; Ingo Ruczinski; Kathleen C Barnes; Juan C Celedón; William O C M Cookson; W James Gauderman; Frank D Gilliland; Hakon Hakonarson; Christoph Lange; Miriam F Moffatt; George T O'Connor; Benjamin A Raby; Edwin K Silverman; Scott Weiss
Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.
American journal of human genetics 2009;84(5):581-93.
2009: Woo Jin Kim; Craig Hersh; Dawn L DeMeo; John Reilly; Edwin K Silverman
Genetic association analysis of COPD candidate genes with bronchodilator responsiveness.
Respiratory medicine 2009;103(4):552-7.
2009: Peter J Castaldi; Craig Hersh; John Reilly; Edwin K Silverman
Genetic associations with hypoxemia and pulmonary arterial pressure in COPD.
Chest 2009;135(3):737-44.
2009: Soumyaroop Bhattacharya; Sorachai Srisuma; Dawn L Demeo; Steven D Shapiro; Raphael Bueno; Edwin K Silverman; John Reilly; Thomas J Mariani
Molecular biomarkers for quantitative and discrete COPD phenotypes.
American journal of respiratory cell and molecular biology 2009;40(3):359-67.
2009: James C Ross; Raúl San José Estépar; Alejandro Díaz; Carl-Fredrik Westin; Ron Kikinis; Edwin K Silverman; George R Washko
Lung extraction, lobe segmentation and hierarchical region assessment for quantitative analysis on high resolution computed tomography images.
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 2009;12(Pt 2):690-8.
2009: Dawn L DeMeo; Edward J Campbell; M L Brantly; Alan Freund Barker; E Eden; N G McElvaney; Stephen I Rennard; James M Stocks; James K Stoller; Charlton B. Strange; G Turino; R A Sandhaus; Edwin K Silverman
Heritability of lung function in severe alpha-1 antitrypsin deficiency.
Human heredity 2009;67(1):38-45.
2008: Raúl San José-Estépar; John Reilly; Edwin K Silverman; George R Washko
Three-dimensional airway measurements and algorithms.
Proceedings of the American Thoracic Society 2008;5(9):905-9.
2008: Michael H Cho; Dawn Ciulla; Barbara J Klanderman; Benjamin A Raby; Edwin K Silverman
High-resolution melting curve analysis of genomic and whole-genome amplified DNA.
Clinical chemistry 2008;54(12):2055-8.
2008: Marilyn G Foreman; Dawn L DeMeo; Craig Hersh; Vincent J Carey; Vincent S Fan; John Reilly; Steven D Shapiro; Edwin K Silverman
Polymorphic variation in surfactant protein B is associated with COPD exacerbations.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2008;32(4):938-44.
2008: Stijn Vansteelandt; Dawn L DeMeo; Jessica Lasky-Su; Jordan W Smoller; Amy J Murphy; Matt McQueen; Kady Schneiter; Juan C Celedon; Scott Weiss; Edwin K Silverman; Christoph Lange
Testing and estimating gene-environment interactions in family-based association studies.
Biometrics 2008;64(2):458-67.
2008: Michael H Cho; Barbara J Klanderman; Augusto A Litonjua; David Sparrow; Edwin K Silverman; Benjamin A Raby
Folliculin mutations are not associated with severe COPD.
BMC medical genetics 2008;9():120.
2008: Dawn L DeMeo; Edward J Campbell; Alan Freund Barker; Mark L Brantly; Edward Eden; Noel G McElvaney; Stephen I Rennard; Robert A Sandhaus; James M Stocks; James K Stoller; Charlton B. Strange; Gerard M Turino; Edwin K Silverman
IL10 polymorphisms are associated with airflow obstruction in severe alpha1-antitrypsin deficiency.
American journal of respiratory cell and molecular biology 2008;38(1):114-20.
2007: Edwin K Silverman
Exacerbations in chronic obstructive pulmonary disease: do they contribute to disease progression?
Proceedings of the American Thoracic Society 2007;4(8):586-90.
2007: Craig Hersh; Francine L Jacobson; Ritu Gill; Edwin K Silverman
Computed tomography phenotypes in severe, early-onset chronic obstructive pulmonary disease.
COPD 2007;4(4):331-7.
2007: Marilyn G Foreman; Dawn L DeMeo; Craig Hersh; John Reilly; Edwin K Silverman
Clinical determinants of exacerbations in severe, early-onset COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;30(6):1124-30.
2007: Dawn L DeMeo; Robert A Sandhaus; Alan Freund Barker; Mark L Brantly; Edward Eden; Noel G McElvaney; Stephen I Rennard; Esteban Burchard; James M Stocks; James K Stoller; Charlton B. Strange; Gerard M Turino; Edward J Campbell; Edwin K Silverman
Determinants of airflow obstruction in severe alpha-1-antitrypsin deficiency.
Thorax 2007;62(9):806-13.
2007: Florence T Wang; Howard Hu; Joel Schwartz; Jennifer Weuve; Avron Spiro; David Sparrow; Huiling Nie; Edwin K Silverman; Scott Weiss; Robert O Wright
Modifying effects of the HFE polymorphisms on the association between lead burden and cognitive decline.
Environmental health perspectives 2007;115(8):1210-5.
2007: Benjamin A Raby; Barbara J Klanderman; Amy Murphy; Salvatore Mazza; Carlos A Camargo; Edwin K Silverman; Scott Weiss
A common mitochondrial haplogroup is associated with elevated total serum IgE levels.
The Journal of allergy and clinical immunology 2007;120(2):351-8.
2007: Gary M Hunninghake; Manuel E Soto-Quirós; Lydiana Avila; Jessica Su; Amy Murphy; Dawn L DeMeo; Ngoc P Ly; Catherine Liang; Jody S Sylvia; Barbara J Klanderman; Christoph Lange; Benjamin A Raby; Edwin K Silverman; Juan C Celedón
Polymorphisms in IL13, total IgE, eosinophilia, and asthma exacerbations in childhood.
The Journal of allergy and clinical immunology 2007;120(1):84-90.
2007: Dawn L DeMeo; Craig Hersh; Eric A Hoffman; Augusto A Litonjua; Ross Lazarus; David Sparrow; Joshua O Benditt; Gerard J Criner; Barry Make; Fernando J Martinez; Paul D Scanlon; Frank C Sciurba; James P Utz; John Reilly; Edwin K Silverman
Genetic determinants of emphysema distribution in the national emphysema treatment trial.
American journal of respiratory and critical care medicine 2007;176(1):42-8.
2007: Gary M Hunninghake; Manuel E Soto-Quiros; Lydiana Avila; Ngoc P Ly; Catherine Liang; Jody S Sylvia; Barbara J Klanderman; Edwin K Silverman; Juan C Celedón
Sensitization to Ascaris lumbricoides and severity of childhood asthma in Costa Rica.
The Journal of allergy and clinical immunology 2007;119(3):654-61.
2007: Hara Levy; Leslie A Kalish; Ian Huntington; Nathaniel Weller; Craig Gerard; Edwin K Silverman; Juan C Celedón; Gerald B Pier; Scott Weiss
Inflammatory markers of lung disease in adult patients with cystic fibrosis.
Pediatric pulmonology 2007;42(3):256-62.
2007: Craig Hersh; Manuel E Soto-Quirós; Lydiana Avila; Stephen L Lake; Catherine Liang; Eduardo Fournier; Mitzi Spesny; Jody S Sylvia; Ross Lazarus; Thomas Hudson; Andrei Verner; Barbara J Klanderman; Nelson B Freimer; Edwin K Silverman; Juan C Celedón
Genome-wide linkage analysis of pulmonary function in families of children with asthma in Costa Rica.
Thorax 2007;62(3):224-30.
2007: Craig Hersh; George R Washko; Francine L Jacobson; Ritu Gill; Raul San Jose Estepar; John Reilly; Edwin K Silverman
Interobserver variability in the determination of upper lobe-predominant emphysema.
Chest 2007;131(2):424-31.
2007: Benjamin A Raby; Manuel E Soto-Quiros; Lydiana Avila; Stephen L Lake; Amy Murphy; Catherine Liang; Eduardo Fournier; Mitzi Spesny; Jody S Sylvia; Andrei Verner; Thomas J Hudson; Barbara J Klanderman; Nelson B Freimer; Edwin K Silverman; Juan C Celedón
Sex-specific linkage to total serum immunoglobulin E in families of children with asthma in Costa Rica.
Human molecular genetics 2007;16(3):243-53.
2007: Craig Hersh; Dawn L DeMeo; John Reilly; Edwin K Silverman
Xenobiotic metabolizing enzyme gene polymorphisms predict response to lung volume reduction surgery.
Respiratory research 2007;8():59.
2007: Edwin K Silverman
Haplotype thinking in lung disease.
Proceedings of the American Thoracic Society 2007;4(1):4-8.
2007: Juan C Celedón; Manuel E Soto-Quiros; Lydiana Avila; Stephen L Lake; Catherine Liang; Eduardo Fournier; Mitzi Spesny; Craig Hersh; Jody S Sylvia; Thomas J Hudson; Andrei Verner; Barbara J Klanderman; Nelson B Freimer; Edwin K Silverman; Scott Weiss
Significant linkage to airway responsiveness on chromosome 12q24 in families of children with asthma in Costa Rica.
Human genetics 2007;120(5):691-9.
2006: Craig Hersh; Dawn L DeMeo; Benjamin A Raby; Augusto A Litonjua; Jody S Sylvia; David Sparrow; John Reilly; Edwin K Silverman
Genetic linkage and association analysis of COPD-related traits on chromosome 8p.
COPD 2006;3(4):189-94.
2006: Craig Hersh; David T Miller; David J Kwiatkowski; Edwin K Silverman
Genetic determinants of C-reactive protein in COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2006;28(6):1156-62.
2006: Dawn L DeMeo; Thomas J Mariani; Christoph Lange; Stephen L Lake; Augusto A Litonjua; Juan Celedón; John Reilly; Harold A Chapman; David Sparrow; Avrum Spira; Jennifer Beane; Victor Pinto-Plata; Frank E Speizer; Steve Shapiro; Scott Weiss; Edwin K Silverman
The SERPINE2 gene is associated with chronic obstructive pulmonary disease.
Proceedings of the American Thoracic Society 2006;3(6):502.
2006: Craig Hersh; Dawn L DeMeo; Ross Lazarus; Juan C Celedón; Benjamin A Raby; John Reilly; Edwin K Silverman
Genetic determinants of functional impairment in chronic obstructive pulmonary disease.
Proceedings of the American Thoracic Society 2006;3(6):476.
2006: Soumyaroop Bhattacharya; Sorachai Srisuma; Dawn L DeMeo; John Reilly; Raphael Bueno; Edwin K Silverman; Thomas J Mariani
Microarray data-based prioritization of chronic obstructive pulmonary disease susceptibility genes.
Proceedings of the American Thoracic Society 2006;3(6):472.
2006: Edwin K Silverman
Progress in chronic obstructive pulmonary disease genetics.
Proceedings of the American Thoracic Society 2006;3(5):405-8.
2006: Craig Hersh; Dawn L DeMeo; Ross Lazarus; Juan C Celedón; Benjamin A Raby; Joshua O Benditt; Gerard J Criner; Barry Make; Fernando J Martinez; Paul D Scanlon; Frank C Sciurba; James P Utz; John Reilly; Edwin K Silverman
Genetic association analysis of functional impairment in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2006;173(9):977-84.
2006: Benjamin A Raby; Kristel van Steen; Ross Lazarus; Juan C Celedón; Edwin K Silverman; Scott Weiss
Eotaxin polymorphisms and serum total IgE levels in children with asthma.
The Journal of allergy and clinical immunology 2006;117(2):298-305.
2006: Dawn L DeMeo; Thomas J Mariani; Christoph Lange; Sorachai Srisuma; Augusto A Litonjua; Juan C Celedon; Stephen L Lake; John Reilly; Harold A Chapman; Brigham H Mecham; Kathleen J Haley; Jody S Sylvia; David Sparrow; Avrum Spira; Jennifer Beane; Victor Pinto-Plata; Frank E Speizer; Steven D Shapiro; Scott Weiss; Edwin K Silverman
The SERPINE2 gene is associated with chronic obstructive pulmonary disease.
American journal of human genetics 2006;78(2):253-64.
2006: Raúl San José Estépar; George G Washko; Edwin K Silverman; John Reilly; Ron Kikinis; Carl-Fredrik Westin
Accurate airway wall estimation using phase congruency.
Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention 2006;9(Pt 2):125-34.
2006: Benjamin A Raby; Eun-Sook Hwang; Kristel van Steen; Kelan G Tantisira; Stanford Peng; Augusto A Litonjua; Ross Lazarus; Cosmas Giallourakis; John D Rioux; David Sparrow; Edwin K Silverman; Laurie H Glimcher; Scott Weiss
T-bet polymorphisms are associated with asthma and airway hyperresponsiveness.
American journal of respiratory and critical care medicine 2006;173(1):64-70.
2005: Cassandra M Kelleher; Edwin K Silverman; Thomas J Broekelmann; Augusto A Litonjua; Melvin Hernandez; Jody S Sylvia; Joan Stoler; John Reilly; Harold A Chapman; Frank E Speizer; Scott Weiss; Robert P Mecham; Benjamin A Raby
A functional mutation in the terminal exon of elastin in severe, early-onset chronic obstructive pulmonary disease.
American journal of respiratory cell and molecular biology 2005;33(4):355-62.
2005: Dawn L DeMeo; John Reilly; Leo C Ginns; Jody S Sylvia; Edwin K Silverman
Concordance of genotypes in pre- and post-lung transplantation DNA samples.
American journal of respiratory cell and molecular biology 2005;33(4):402-5.
2005: Adrienne G Randolph; Christoph Lange; Edwin K Silverman; Ross Lazarus; Scott Weiss
Extended haplotype in the tumor necrosis factor gene cluster is associated with asthma and asthma-related phenotypes.
American journal of respiratory and critical care medicine 2005;172(6):687-92.
2005: Shweta Choudhry; Pedro C Avila; Sylvette Nazario; Ngim Ung; Jennifer Kho; Jose R Rodriguez-Santana; Jesus Casal; Hui-Ju Tsai; Alfonso Torres; Elad Ziv; Monica Toscano; Jody S Sylvia; MariaElena Alioto; Michael Salazar; Ivan Gomez; Joanne K Fagan; Jorge Salas; Craig M Lilly; Henry Matallana; Richard A Castro; Moisés Selman; Scott Weiss; Jean G Ford; Jeffrey M Drazen; William Rodriguez-Cintron; Rocio Chapela; Edwin K Silverman; Esteban González Burchard
CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma.
American journal of respiratory and critical care medicine 2005;172(2):173-82.
2005: M Dahl; Craig Hersh; Ngoc P Ly; Catherine S Berkey; Edwin K Silverman; B G Nordestgaard
The protease inhibitor PI*S allele and COPD: a meta-analysis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2005;26(1):67-76.
2005: Kristel van Steen; Matthew B McQueen; Alan Herbert; Benjamin A Raby; Helen N Lyon; Dawn L DeMeo; Amy Murphy; Jessica Su; Soma Datta; Carsten Rosenow; Michael F Christman; Edwin K Silverman; Nan M Laird; Scott Weiss; Christoph Lange
Genomic screening and replication using the same data set in family-based association testing.
Nature genetics 2005;37(7):683-91.
2005: Craig Hersh; Dawn L DeMeo; Christoph Lange; Augusto A Litonjua; John Reilly; David Kwiatkowski; Nan M Laird; Jody S Sylvia; David Sparrow; Frank E Speizer; Scott Weiss; Edwin K Silverman
Attempted replication of reported chronic obstructive pulmonary disease candidate gene associations.
American journal of respiratory cell and molecular biology 2005;33(1):71-8.
2005: Hara Levy; Benjamin A Raby; Stephen L Lake; Kelan G Tantisira; David Kwiatkowski; Ross Lazarus; Edwin K Silverman; Brent Richter; Walter T Klimecki; Donata Vercelli; Fernando D Martinez; Scott Weiss
Association of defensin beta-1 gene polymorphisms with asthma.
The Journal of allergy and clinical immunology 2005;115(2):252-8.
2004: Dawn L DeMeo; Juan C Celedón; Christoph Lange; John Reilly; Harold A Chapman; Jody S Sylvia; Frank E Speizer; Scott Weiss; Edwin K Silverman
Genome-wide linkage of forced mid-expiratory flow in chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2004;170(12):1294-301.
2004: Benjamin A Raby; Ross Lazarus; Edwin K Silverman; Stephen L Lake; Christoph Lange; Matthias Wjst; Scott Weiss
Association of vitamin D receptor gene polymorphisms with childhood and adult asthma.
American journal of respiratory and critical care medicine 2004;170(10):1057-65.
2004: Craig Hersh; Dawn L DeMeo; Essam Al-Ansari; Vincent J Carey; John Reilly; Leo C Ginns; Edwin K Silverman
Predictors of survival in severe, early onset COPD.
Chest 2004;126(5):1443-51.
2004: Craig Hersh; M Dahl; Ngoc P Ly; Catherine S Berkey; B G Nordestgaard; Edwin K Silverman
Chronic obstructive pulmonary disease in alpha1-antitrypsin PI MZ heterozygotes: a meta-analysis.
Thorax 2004;59(10):843-9.
2004: Adrienne G Randolph; Christoph Lange; Edwin K Silverman; Ross Lazarus; Eric S Silverman; Benjamin A Raby; Alison Brown; Al Ozonoff; Brent Richter; Scott Weiss
The IL12B gene is associated with asthma.
American journal of human genetics 2004;75(4):709-15.
2004: Ross Lazarus; Benjamin A Raby; Christoph Lange; Edwin K Silverman; David J Kwiatkowski; Donata Vercelli; Walt J Klimecki; Fernando D Martinez; Scott Weiss
TOLL-like receptor 10 genetic variation is associated with asthma in two independent samples.
American journal of respiratory and critical care medicine 2004;170(6):594-600.
2004: Juan C Celedón; Christoph Lange; Benjamin A Raby; Augusto A Litonjua; Lyle Palmer; Dawn L DeMeo; John Reilly; David J Kwiatkowski; Harold A Chapman; Nan M Laird; Jody S Sylvia; Melvin Hernandez; Frank E Speizer; Scott Weiss; Edwin K Silverman
The transforming growth factor-beta1 (TGFB1) gene is associated with chronic obstructive pulmonary disease (COPD).
Human molecular genetics 2004;13(15):1649-56.
2004: Augusto A Litonjua; Edwin K Silverman; Kelan G Tantisira; David Sparrow; Jody S Sylvia; Scott Weiss
Beta 2-adrenergic receptor polymorphisms and haplotypes are associated with airways hyperresponsiveness among nonsmoking men.
Chest 2004;126(1):66-74.
2004: Kelan G Tantisira; Stephen L Lake; Eric S Silverman; Lyle Palmer; Ross Lazarus; Edwin K Silverman; Stephen B Liggett; Erwin W Gelfand; Lanny J Rosenwasser; Brent Richter; Elliot Israel; Michael E Wechsler; Stacey Gabriel; David Altshuler; Eric Lander; Jeffrey M Drazen; Scott Weiss
Corticosteroid pharmacogenetics: association of sequence variants in CRHR1 with improved lung function in asthmatics treated with inhaled corticosteroids.
Human molecular genetics 2004;13(13):1353-9.
2004: Benjamin A Raby; Edwin K Silverman; David J Kwiatkowski; Christoph Lange; Ross Lazarus; Scott Weiss
ADAM33 polymorphisms and phenotype associations in childhood asthma.
The Journal of allergy and clinical immunology 2004;113(6):1071-8.
2004: Robert O Wright; Edwin K Silverman; Joel Schwartz; Shirng-Wern Tsaih; Jody M Senter; David Sparrow; Scott Weiss; Antonio Aro; Howard Hu
Association between hemochromatosis genotype and lead exposure among elderly men: the normative aging study.
Environmental health perspectives 2004;112(6):746-50.
2004: Dawn L DeMeo; Edwin K Silverman
Alpha1-antitrypsin deficiency. 2: genetic aspects of alpha(1)-antitrypsin deficiency: phenotypes and genetic modifiers of emphysema risk.
Thorax 2004;59(3):259-64.
2004: Helen N Lyon; Christoph Lange; Stephen L Lake; Edwin K Silverman; Adrienne G Randolph; David Kwiatkowski; Benjamin A Raby; Ross Lazarus; Katy M Weiland; Nan M Laird; Scott Weiss
IL10 gene polymorphisms are associated with asthma phenotypes in children.
Genetic epidemiology 2004;26(2):155-65.
2004: Esteban González Burchard; Pedro C Avila; Sylvette Nazario; Jesus Casal; Alfonso Torres; Jose R Rodriguez-Santana; Monica Toscano; Jody S Sylvia; MariaElena Alioto; Michael Salazar; Ivan Gomez; Joanne K Fagan; Jorge Salas; Craig M Lilly; Henry Matallana; Elad Ziv; Richard Castro; Moisés Selman; Rocio Chapela; Dean Sheppard; Scott Weiss; Jean G Ford; Homer A Boushey; William Rodriguez-Cintron; Jeffrey M Drazen; Edwin K Silverman
Lower bronchodilator responsiveness in Puerto Rican than in Mexican subjects with asthma.
American journal of respiratory and critical care medicine 2004;169(3):386-92.
2004: Christoph Lange; Kristel van Steen; Toby Andrew; Helen N Lyon; Dawn L DeMeo; Benjamin A Raby; Amy Murphy; Edwin K Silverman; Alex MacGregor; Scott Weiss; Nan M Laird
A family-based association test for repeatedly measured quantitative traits adjusting for unknown environmental and/or polygenic effects.
Statistical applications in genetics and molecular biology 2004;3():Article17.
2004: Scott Weiss; Stephen L Lake; Eric S Silverman; Edwin K Silverman; Brent Richter; Jeffrey M Drazen; Kelan G Tantisira
Asthma steroid pharmacogenetics: a study strategy to identify replicated treatment responses.
Proceedings of the American Thoracic Society 2004;1(4):364-7.
2004: Steve Horvath; Xin Xu; Stephen L Lake; Edwin K Silverman; Scott Weiss; Nan M Laird
Family-based tests for associating haplotypes with general phenotype data: application to asthma genetics.
Genetic epidemiology 2004;26(1):61-9.
2003: Denise L Lind; Shweta Choudhry; Ngim Ung; Elad Ziv; Pedro C Avila; Keyan Salari; Connie Ha; Elizabeth G Lovins; Natasha E Coyle; Sylvette Nazario; Jesus Casal; Alfonso Torres; Jose R Rodriguez-Santana; Henry Matallana; Craig M Lilly; Jorge Salas; Moisés Selman; Homer A Boushey; Scott Weiss; Rocio Chapela; Jean G Ford; William Rodriguez-Cintron; Edwin K Silverman; Dean Sheppard; Pui-Yan Kwok; Esteban González Burchard
ADAM33 is not associated with asthma in Puerto Rican or Mexican populations.
American journal of respiratory and critical care medicine 2003;168(11):1312-6.
2003: Robert O Wright; Howard Hu; Edwin K Silverman; Shirng-Wern Tsaih; Joel Schwartz; David Bellinger; Eduardo Palazuelos; Scott Weiss; Mauricio Hernandez-Avila
Apolipoprotein E genotype predicts 24-month bayley scales infant development score.
Pediatric research 2003;54(6):819-25.
2003: Edwin K Silverman; David J Kwiatkowski; Jody S Sylvia; Ross Lazarus; Jeffrey M Drazen; Christoph Lange; Nan M Laird; Scott Weiss
Family-based association analysis of beta2-adrenergic receptor polymorphisms in the childhood asthma management program.
The Journal of allergy and clinical immunology 2003;112(5):870-6.
2003: Christoph Lange; Dawn L DeMeo; Edwin K Silverman; Scott Weiss; Nan M Laird
Using the noninformative families in family-based association tests: a powerful new testing strategy.
American journal of human genetics 2003;73(4):801-11.
2003: Benjamin A Raby; Edwin K Silverman; Ross Lazarus; Christoph Lange; David J Kwiatkowski; Scott Weiss
Chromosome 12q harbors multiple genetic loci related to asthma and asthma-related phenotypes.
Human molecular genetics 2003;12(16):1973-9.
2003: Lyle Palmer; Juan C Celedón; Harold A Chapman; Frank E Speizer; Scott Weiss; Edwin K Silverman
Genome-wide linkage analysis of bronchodilator responsiveness and post-bronchodilator spirometric phenotypes in chronic obstructive pulmonary disease.
Human molecular genetics 2003;12(10):1199-210.
2003: Dawn L DeMeo; Edwin K Silverman
Genetics of chronic obstructive pulmonary disease.
Seminars in respiratory and critical care medicine 2003;24(2):151-60.
2003: Christoph Lange; Edwin K Silverman; Xin Xu; Scott Weiss; Nan M Laird
A multivariate family-based association test using generalized estimating equations: FBAT-GEE.
Biostatistics (Oxford, England) 2003;4(2):195-206.
2003: Christoph Lange; Helen N Lyon; Dawn L DeMeo; Benjamin A Raby; Edwin K Silverman; Scott Weiss
A new powerful non-parametric two-stage approach for testing multiple phenotypes in family-based association studies.
Human heredity 2003;56(1-3):10-7.
2003: Stephen L Lake; Helen N Lyon; Kelan G Tantisira; Edwin K Silverman; Scott Weiss; Nan M Laird; D J Schaid
Estimation and tests of haplotype-environment interaction when linkage phase is ambiguous.
Human heredity 2003;55(1):56-65.
2003: Ross Lazarus; Walter T Klimecki; Benjamin A Raby; Donata Vercelli; Lyle Palmer; David J Kwiatkowski; Edwin K Silverman; Fernando D Martinez; Scott Weiss
Single-nucleotide polymorphisms in the Toll-like receptor 9 gene (TLR9): frequencies, pairwise linkage disequilibrium, and haplotypes in three U.S. ethnic groups and exploratory case-control disease association studies.
Genomics 2003;81(1):85-91.
2002: Ross Lazarus; Donata Vercelli; Lyle Palmer; Walt J Klimecki; Edwin K Silverman; Brent Richter; Alberto Riva; Marco F Ramoni; Fernando D Martinez; Scott Weiss; David J Kwiatkowski
Single nucleotide polymorphisms in innate immunity genes: abundant variation and potential role in complex human disease.
Immunological reviews 2002;190():9-25.
2002: Benjamin A Raby; Walter T Klimecki; Catherine Laprise; Yannick Renaud; Janet Faith; Mathieu Lemire; Celia Greenwood; Katherine M Weiland; Christoph Lange; Lyle Palmer; Ross Lazarus; Donata Vercelli; David J Kwiatkowski; Edwin K Silverman; Fernando D Martinez; Thomas J Hudson; Scott Weiss
Polymorphisms in toll-like receptor 4 are not associated with asthma or atopy-related phenotypes.
American journal of respiratory and critical care medicine 2002;166(11):1449-56.
2002: Dawn L DeMeo; Christoph Lange; Edwin K Silverman; Jody M Senter; Jeffrey M Drazen; M J Barth; Nan M Laird; Scott Weiss
Univariate and multivariate family-based association analysis of the IL-13 ARG130GLN polymorphism in the Childhood Asthma Management Program.
Genetic epidemiology 2002;23(4):335-48.
2002: Ross Lazarus; Walter T Klimecki; Lyle Palmer; David J Kwiatkowski; Edwin K Silverman; Alison Brown; Fernando D Martinez; Scott Weiss
Single-nucleotide polymorphisms in the interleukin-10 gene: differences in frequencies, linkage disequilibrium patterns, and haplotypes in three United States ethnic groups.
Genomics 2002;80(2):223-8.
2002: Edwin K Silverman; Lyle Palmer; Jonathan D Mosley; Matthew Barth; Jody M Senter; Alison Brown; Jeffrey M Drazen; David J Kwiatkowski; Harold A Chapman; Edward J Campbell; Michael A Province; D C Rao; John Reilly; Leo C Ginns; Frank E Speizer; Scott Weiss
Genomewide linkage analysis of quantitative spirometric phenotypes in severe early-onset chronic obstructive pulmonary disease.
American journal of human genetics 2002;70(5):1229-39.
2002: Manuel E Soto-Quiros; Edwin K Silverman; Lars A Hanson; Scott Weiss; Juan C Celedón
Maternal history, sensitization to allergens, and current wheezing, rhinitis, and eczema among children in Costa Rica.
Pediatric pulmonology 2002;33(4):237-43.
2002: Edwin K Silverman; Jonathan D Mosley; Lyle Palmer; Matthew Barth; Jody M Senter; Alison Brown; Jeffrey M Drazen; David J Kwiatkowski; Harold A Chapman; Edward J Campbell; Michael A Province; D C Rao; John Reilly; Leo C Ginns; Frank E Speizer; Scott Weiss
Genome-wide linkage analysis of severe, early-onset chronic obstructive pulmonary disease: airflow obstruction and chronic bronchitis phenotypes.
Human molecular genetics 2002;11(6):623-32.
2002: Juan C Celedón; Manuel E Soto-Quiros; Lyle Palmer; Jody M Senter; Jonathan D Mosley; Edwin K Silverman; Scott Weiss
Lack of association between a polymorphism in the interleukin-13 gene and total serum immunoglobulin E level among nuclear families in Costa Rica.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 2002;32(3):387-90.
2002: Edwin K Silverman
Genetic Epidemiology of COPD.
Chest 2002;121(3 Suppl):1S-6S.
2001: Juan C Celedón; Manuel E Soto-Quiros; Edwin K Silverman; L Hanson; Scott Weiss
Risk factors for childhood asthma in Costa Rica.
Chest 2001;120(3):785-90.
2001: Edwin K Silverman; Jonathan D Mosley; D C Rao; Lyle Palmer; Michael A Province; Robert C Elston; Scott Weiss; Edward J Campbell
Linkage analysis of alpha 1-antitrypsin deficiency: lessons for complex diseases.
Human heredity 2001;52(4):223-32.
2001: Elliot Israel; Jeffrey M Drazen; Stephen B Liggett; Homer A Boushey; Reuben M Cherniack; Vernon M Chinchilli; Dan M Cooper; John V Fahy; James E Fish; Jean G Ford; Monica Kraft; Susan J Kunselman; Stephen C Lazarus; Robert F Lemanske; Richard J Martin; Diane E McLean; Stephen P Peters; Edwin K Silverman; Christine A Sorkness; Stanley J Szefler; Scott Weiss; CN Yandava
Effect of polymorphism of the beta(2)-adrenergic receptor on response to regular use of albuterol in asthma.
International archives of allergy and immunology 2001;124(1-3):183-6.
2001: Edwin K Silverman
Genetics of chronic obstructive pulmonary disease.
Novartis Foundation symposium 2001;234():45-58; discussion 58-64.
2000: Edwin K Silverman; Scott Weiss; Jeffrey M Drazen; Harold A Chapman; Vincent J Carey; Edward J Campbell; P Denish; R A Silverman; Juan C Celedon; John Reilly; Leo C Ginns; Frank E Speizer
Gender-related differences in severe, early-onset chronic obstructive pulmonary disease.
American journal of respiratory and critical care medicine 2000;162(6):2152-8.
2000: Michael E Wechsler; Hartmut Grasemann; Aaron Deykin; Edwin K Silverman; CN Yandava; Elliot Israel; Matthew Wand; Jeffrey M Drazen
Exhaled nitric oxide in patients with asthma: association with NOS1 genotype.
American journal of respiratory and critical care medicine 2000;162(6):2043-7.
2000: Juan C Celedon; Edwin K Silverman; Scott Weiss; Binyan Wang; Zhian Fang; Xiping Xu
Application of an algorithm for the diagnosis of asthma in Chinese families: limitations and alternatives for the phenotypic assessment of asthma in family-based genetic studies.
American journal of respiratory and critical care medicine 2000;162(5):1679-84.
2000: Elliot Israel; Jeffrey M Drazen; Stephen B Liggett; Homer A Boushey; Reuben M Cherniack; Vernon M Chinchilli; Dan M Cooper; John V Fahy; James E Fish; Jean G Ford; Monica Kraft; Susan J Kunselman; Stephen C Lazarus; Robert F Lemanske; Richard J Martin; Diane E McLean; Stephen P Peters; Edwin K Silverman; Christine A Sorkness; Stanley J Szefler; Scott Weiss; CN Yandava
The effect of polymorphisms of the beta(2)-adrenergic receptor on the response to regular use of albuterol in asthma.
American journal of respiratory and critical care medicine 2000;162(1):75-80.
2000: Hartmut Grasemann; CN Yandava; Karin Storm van's Gravesande; Aaron Deykin; A Pillari; J Ma; Larry A Sonna; Craig M Lilly; M J Stampfer; Elliot Israel; Edwin K Silverman; Jeffrey M Drazen
A neuronal NO synthase (NOS1) gene polymorphism is associated with asthma.
Biochemical and biophysical research communications 2000;272(2):391-4.
2000: Jeffrey M Drazen; Edwin K Silverman; T H Lee
Heterogeneity of therapeutic responses in asthma.
British medical bulletin 2000;56(4):1054-70.
1999: Juan C Celedon; Frank E Speizer; Jeffrey M Drazen; Scott Weiss; Edward J Campbell; Vincent J Carey; John Reilly; Leo C Ginns; Edwin K Silverman
Bronchodilator responsiveness and serum total IgE levels in families of probands with severe early-onset COPD.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;14(5):1009-14.
1999: Esteban González Burchard; Edwin K Silverman; Lanny J Rosenwasser; Larry Borish; CN Yandava; A Pillari; Scott Weiss; Jeffrey D Hasday; Craig M Lilly; Jean G Ford; Jeffrey M Drazen
Association between a sequence variant in the IL-4 gene promoter and FEV(1) in asthma.
American journal of respiratory and critical care medicine 1999;160(3):919-22.
1998: Edwin K Silverman; Harold A Chapman; Jeffrey M Drazen; Scott Weiss; B Rosner; Edward J Campbell; W J O'DONNELL; John Reilly; Leo C Ginns; Steven J Mentzer; John Wain; Frank E Speizer
Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis.
American journal of respiratory and critical care medicine 1998;157(6 Pt 1):1770-8.
1997: Jeffrey M Drazen; Edwin K Silverman
Genetics of asthma: conference summary.
American journal of respiratory and critical care medicine 1997;156(4 Pt 2):S69-71.
1997: KH In; K Asano; D Beier; J Grobholz; Patricia W Finn; Edwin K Silverman; Eric S Silverman; T Collins; AR Fischer; T P Keith; K Serino; S W Kim; George T De Sanctis; CN Yandava; A Pillari; P Rubin; J Kemp; Elliot Israel; W Busse; D Ledford; John Joseph Murray; A Segal; D Tinkleman; Jeffrey M Drazen
Naturally occurring mutations in the human 5-lipoxygenase gene promoter that modify transcription factor binding and reporter gene transcription.
The Journal of clinical investigation 1997;99(5):1130-7.
1996: Edwin K Silverman; Frank E Speizer
Risk factors for the development of chronic obstructive pulmonary disease.
The Medical clinics of North America 1996;80(3):501-22.