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Cedric Bobst

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Publications

TOP 3
Son N Nguyen; Cedric E Bobst; Igor A Kaltashov
Mass spectrometry-guided optimization and characterization of a biologically active transferrin-lysozyme model drug conjugate.
Igor A Kaltashov; Cedric E Bobst; Rinat R Abzalimov
Mass spectrometry-based methods to study protein architecture and dynamics.
Gauri S Joshi; Cedric E Bobst; Michael Zianni; F Robert Tabita
Regulatory twist and synergistic role of metabolic coinducer- and response regulator-mediated CbbR-cbbI interactions in Rhodopseudomonas palustris CGA010.

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All Publications

2013: Son N Nguyen; Cedric E Bobst; Igor A Kaltashov
Mass spectrometry-guided optimization and characterization of a biologically active transferrin-lysozyme model drug conjugate.
Molecular pharmaceutics 2013;10(5):1998-2007.
2013: Igor A Kaltashov; Cedric E Bobst; Rinat R Abzalimov
Mass spectrometry-based methods to study protein architecture and dynamics.
Protein science : a publication of the Protein Society 2013;22(5):530-44.
2013: Gauri S Joshi; Cedric E Bobst; Michael Zianni; F Robert Tabita
Regulatory twist and synergistic role of metabolic coinducer- and response regulator-mediated CbbR-cbbI interactions in Rhodopseudomonas palustris CGA010.
Journal of bacteriology 2013;195(7):1381-8.
2013: Rinat R Abzalimov; Cedric E Bobst; Paul A Salinas; Philip Savickas; John J Thomas; Igor A Kaltashov
Studies of pH-dependent self-association of a recombinant form of arylsulfatase A with electrospray ionization mass spectrometry and size-exclusion chromatography.
Analytical chemistry 2013;85(3):1591-6.
2012: Ashley N Steere; Deshui Zhang; Steve C Pettit; Cedric E Bobst; Ning Huang; Igor A Kaltashov; Anne B Mason
Biochemical and structural characterization of recombinant human serum transferrin from rice (Oryza sativa L.).
Journal of inorganic biochemistry 2012;116():37-44.
2012: Cedric E Bobst; Wei-Chiang Shen; Shunhai Wang; Igor A Kaltashov
Mass spectrometry study of a transferrin-based protein drug reveals the key role of protein aggregation for successful oral delivery.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(34):13544-8.
2012: Gauri S Joshi; Cedric E Bobst; Michael Zianni; F Robert Tabita
Further unraveling the regulatory twist by elucidating metabolic coinducer-mediated CbbR-cbbI promoter interactions in Rhodopseudomonas palustris CGA010.
Journal of bacteriology 2012;194(6):1350-60.
2012: Igor A Kaltashov; Rachael Leverence; Mingxuan Zhang; Cedric E Bobst; Dmitry R Gumerov
Transferrin as a model system for method development to study structure, dynamics and interactions of metalloproteins using mass spectrometry.
Biochimica et biophysica acta 2012;1820(3):417-26.
2012: Cedric E Bobst; Igor A Kaltashov
Localizing flexible regions in proteins using hydrogen-deuterium exchange mass spectrometry.
Methods in molecular biology (Clifton, N.J.) 2012;896():375-85.
2012: Igor A Kaltashov; Guanbo Wang; Rinat R Abzalimov; Burcu Baykal; Cedric E Bobst; Shunhai Wang
Advances and challenges in analytical characterization of biotechnology products: mass spectrometry-based approaches to study properties and behavior of protein therapeutics.
Biotechnology advances 2012;30(1):210-22.
2011: Cedric E Bobst; Igor A Kaltashov
Advanced mass spectrometry-based methods for the analysis of conformational integrity of biopharmaceutical products.
Current pharmaceutical biotechnology 2011;12(10):1517-29.
2011: Shunhai Wang; Cedric E Bobst; Igor A Kaltashov
Pitfalls in protein quantitation using acid-catalyzed O18 labeling: hydrolysis-driven deamidation.
Analytical chemistry 2011;83(18):7227-32.
2011: Gauri S Joshi; Cedric E Bobst; F Robert Tabita
Unravelling the regulatory twist--regulation of CO2 fixation in Rhodopseudomonas palustris CGA010 mediated by atypical response regulator(s).
Molecular microbiology 2011;80(3):756-71.
2010: Cedric E Bobst; John J Thomas; Paul A Salinas; Philip Savickas; Igor A Kaltashov
Impact of oxidation on protein therapeutics: conformational dynamics of intact and oxidized acid-β-glucocerebrosidase at near-physiological pH.
Protein science : a publication of the Protein Society 2010;19(12):2366-78.
2010: Ashley N Steere; Samantha E Roberts; Shaina L Byrne; N Dennis Chasteen; Cedric E Bobst; Igor A Kaltashov; Valerie C Smith; Ross T A MacGillivray; Anne Mason
Properties of a homogeneous C-lobe prepared by introduction of a TEV cleavage site between the lobes of human transferrin.
Protein expression and purification 2010;72(1):32-41.
2010: Igor A Kaltashov; Cedric E Bobst; Rinat R Abzalimov; Steven A Berkowitz; Damian Houde
Conformation and dynamics of biopharmaceuticals: transition of mass spectrometry-based tools from academe to industry.
Journal of the American Society for Mass Spectrometry 2010;21(3):323-37.
2009: Igor A Kaltashov; Cedric E Bobst; Rinat R Abzalimov
H/D exchange and mass spectrometry in the studies of protein conformation and dynamics: is there a need for a top-down approach?
Analytical chemistry 2009;81(19):7892-9.
2009: Cedric E Bobst; Mingxuan Zhang; Igor A Kaltashov
Existence of a noncanonical state of iron-bound transferrin at endosomal pH revealed by hydrogen exchange and mass spectrometry.
Journal of molecular biology 2009;388(5):954-67.
2009: Anne Mason; Peter J Halbrooks; Nicholas G James; Shaina L Byrne; John K Grady; N Dennis Chasteen; Cedric E Bobst; Igor A Kaltashov; Valerie C Smith; Ross T A MacGillivray; Stephen J Everse
Structural and functional consequences of the substitution of glycine 65 with arginine in the N-lobe of human transferrin.
Biochemistry 2009;48(9):1945-53.
2008: Cedric E Bobst; Rinat R Abzalimov; Damian Houde; Marek Kloczewiak; Rohin Mhatre; Steven A Berkowitz; Igor A Kaltashov
Detection and characterization of altered conformations of protein pharmaceuticals using complementary mass spectrometry-based approaches.
Analytical chemistry 2008;80(19):7473-81.
2004: Cedric E Bobst; F Robert Tabita
The role of cysteine 160 in thiamine diphosphate binding of the Calvin-Benson-Bassham cycle transketolase of Rhodobacter sphaeroides.
Archives of biochemistry and biophysics 2004;426(1):43-54.
2004: Frank W Larimer; Patrick S G Chain; Loren Hauser; Jane Lamerdin; Stephanie Malfatti; Long Do; Miriam Land; Dale A Pelletier; J Thomas Beatty; Andrew S Lang; F Robert Tabita; Janet L Gibson; Thomas Hanson; Cedric E Bobst; Janelle L Torres y Torres; Caroline Peres; Faith H Harrison; Jane Gibson; Caroline S Harwood
Complete genome sequence of the metabolically versatile photosynthetic bacterium Rhodopseudomonas palustris.
Nature biotechnology 2004;22(1):55-61.
2001: K S Yoon; Cedric E Bobst; Craig Hemann; Russ Hille; F Robert Tabita
Spectroscopic and functional properties of novel 2[4Fe-4S] cluster-containing ferredoxins from the green sulfur bacterium Chlorobium tepidum.
The Journal of biological chemistry 2001;276(47):44027-36.