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Meng-Kwoon Sim

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Co-Publications
Name
8
Go, Mei-Lin
8
Tang, Feng Ru
4
Loke, Weng-Keong
4
murugan, dharmani
4
Mustafa, Mohd Rais
3
Achike, Francis
3
Lee, Wei Ling
3
Chen, Woei-Shin
3
Ling, EA
3
Xu, R
3
Min, Le
2
Lim, Siew-Lay
1
Chen, Peng Min
1
Ng, Huck-Hui
1
Phoon, Meng-Chee

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Publications

TOP 3
Narasaraju T; Sim M K; Ng H H; Phoon M C; Shanker N; Lal S K; Chow Vincent T K
Adaptation of human influenza H3N2 virus in a mouse pneumonitis model: insights into viral virulence, tissue tropism and host pathogenesis.
Dharmani M; Mustafa M R; Achike F I; Sim M K
Involvement of AT(1) angiotensin receptors in the vasomodulatory effect of des-aspartate-angiotensin I in the rat renal vasculature.
Sim Meng-Kwoon; Xu Xiao-Guang; Wong Yong-Chiat; Sim Sai-Zhen; Lee Kok-Onn
Des-aspartate-angiotensin I exerts hypoglycemic action via glucose transporter-4 translocation in type 2 diabetic KKAy mice and GK rats.

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All Publications

2009: Narasaraju T; Sim M K; Ng H H; Phoon M C; Shanker N; Lal S K; Chow Vincent T K
Adaptation of human influenza H3N2 virus in a mouse pneumonitis model: insights into viral virulence, tissue tropism and host pathogenesis.
Microbes and infection / Institut Pasteur 2009;11(1):2-11.
2008: Dharmani M; Mustafa M R; Achike F I; Sim M K
Involvement of AT(1) angiotensin receptors in the vasomodulatory effect of des-aspartate-angiotensin I in the rat renal vasculature.
Peptides 2008;29(10):1773-80.
2007: Sim Meng-Kwoon; Xu Xiao-Guang; Wong Yong-Chiat; Sim Sai-Zhen; Lee Kok-Onn
Des-aspartate-angiotensin I exerts hypoglycemic action via glucose transporter-4 translocation in type 2 diabetic KKAy mice and GK rats.
Endocrinology 2007;148(12):5925-32.
2007: Dharmani Murugan; Mustafa Mohd Rais; Achike Francis I; Sim Meng-Kwoon
Effects of angiotensin 1-7 on the actions of angiotensin II in the renal and mesenteric vasculature of hypertensive and streptozotocin-induced diabetic rats.
European journal of pharmacology 2007;561(1-3):144-50.
2006: Sim Meng-Kwoon; Chen Woei-Shin
Effects of losartan on angiotensin receptors in the hypertrophic rat heart.
Regulatory peptides 2006;137(3):140-6.
2005: Loke Weng-Keong; Sim Meng-Kwoon; Go Mei-Lin
Novel neuroprotective effects with O-benzyl derivative of pralidoxime in soman-intoxicated rodents.
European journal of pharmacology 2005;521(1-3):59-69.
2005: Dharmani M; Mustafa M R; Achike F I; Sim M K
Effect of des-aspartate-angiotensin I on the actions of angiotensin II in the isolated renal and mesenteric vasculature of hypertensive and STZ-induced diabetic rats.
Regulatory peptides 2005;129(1-3):213-9.
2005: Sim Meng-Kwoon; Min Le
Des-aspartate-angiotensin I and angiotensin AT1 receptors in rat cardiac ventricles.
Regulatory peptides 2005;129(1-3):133-7.
2004: Chua Hui-Lee; Jois Seetharama; Sim Meng-Kwoon; Go Mei-Lin
Transport of angiotensin peptides across the Caco-2 monolayer.
Peptides 2004;25(8):1327-38.
2004: Wen Qiang; Sim Meng-Kwoon; Tang Feng-Ru
Reduction of infarct size by orally administered des-aspartate-angiotensin I in the ischemic reperfused rat heart.
Regulatory peptides 2004;120(1-3):149-53.
2004: Mustafa M R; Dharmani M; Kunheen N K; Sim M K
Effects of des-aspartate-angiotensin I on the actions of angiotensin III in the renal and mesenteric vasculature of normo- and hypertensive rats.
Regulatory peptides 2004;120(1-3):15-22.
2004: Tang F R; Chia S C; Chen P M; Gao H; Lee W L; Yeo T S; Burgunder J M; Probst A; Sim M K; Ling E A
Metabotropic glutamate receptor 2/3 in the hippocampus of patients with mesial temporal lobe epilepsy, and of rats and mice after pilocarpine-induced status epilepticus.
Epilepsy research 2004;59(2-3):167-80.
2004: Chen W S; Sim M K
Effects of des-aspartate-angiotensin I on the expression of angiotensin AT1 and AT2 receptors in ventricles of hypertrophic rat hearts.
Regulatory peptides 2004;117(3):207-12.
2003: Sim M K; Qui X S
Angiotensins in plasma of hypertensive rats and human.
Regulatory peptides 2003;111(1-3):179-82.
2002: Chen Woei-Shin; Sim Meng-Kwoon; Go Mei-Lin
Structure-activity and structure-binding studies of des-Asp(1)-angiotensin I analogues on the rabbit pulmonary artery.
Regulatory peptides 2002;106(1-3):39-46.
2002: Loke Weng-Keong; Sim Meng-Kwoon; Go Mei-Lin
O-Substituted derivatives of pralidoxime: muscarinic properties and protection against soman effects in rats.
European journal of pharmacology 2002;442(3):279-87.
2002: Somanadhan Brinda; Loke Weng-Keong; Sim Meng-Kwoon; Go Mei-Lin
Quinuclidinone O-Alkynyloximes with muscarinic agonist activity.
Bioorganic & medicinal chemistry 2002;10(1):207-13.
2001: Tham M; Sim M K; Tang F R
Location of renin-angiotensin system components in the hypoglossal nucleus of the rat.
Regulatory peptides 2001;101(1-3):51-7.
2001: Tang F R; Lee W L; Yang J; Sim M K; Ling E A
Expression of metabotropic glutamate receptor 1alpha in the hippocampus of rat pilocarpine model of status epilepticus.
Epilepsy research 2001;46(2):179-89.
2001: Sim M K
Cardiovascular actions of chicken-meat extract in normo- and hypertensive rats.
The British journal of nutrition 2001;86(1):97-103.
2001: Tang F R; Lee W L; Yang J; Sim M K; Ling E A
Metabotropic glutamate receptor 8 in the rat hippocampus after pilocarpine induced status epilepticus.
Neuroscience letters 2001;300(3):137-40.
2000: Min L; Sim M K; Xu X G
Effects of des-aspartate-angiotensin I on angiotensin II-induced incorporation of phenylalanine and thymidine in cultured rat cardiomyocytes and aortic smooth muscle cells.
Regulatory peptides 2000;95(1-3):93-7.
2000: Lim S L; Sim M K; Loke W K
Acetylcholinesterase-independent action of diisopropyl-flurophosphate in the rat aorta.
European journal of pharmacology 2000;404(3):353-9.
2000: Tan L M; Sim M K
Actions of angiotensin peptides on the rabbit pulmonary artery.
Life sciences 2000;66(19):1839-47.
1999: Tang F R; Sim M K
Pre- and/or post-synaptic localisation of metabotropic glutamate receptor 1alpha (mGluR1alpha) and 2/3 (mGluR2/3) in the rat spinal cord.
Neuroscience research 1999;34(2):73-8.
1999: Xu R; Sim M K; Go M L
M3/M1-Selective antimuscarinic tropinyl and piperidinyl esters.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 1999;8(1):39-47.
1998: Xu R; Sim M K; Go M L
Synthesis and pharmacological characterization of O-alkynyloximes of tropinone and N-methylpiperidinone as muscarinic agonists.
Journal of medicinal chemistry 1998;41(17):3220-31.
1998: Han N L; Sim M K
Hypothalamic angiotensin receptor subtypes in normotensive and hypertensive rats.
The American journal of physiology 1998;275(2 Pt 2):H703-9.
1998: Sim M K; Min L
Effects of des-Asp-angiotensin I on experimentally-induced cardiac hypertrophy in rats.
International journal of cardiology 1998;63(3):223-7.
1998: Xu R; Sim M K; Go M L
Synthesis, antimuscarinic activity and quantitative structure-activity relationship (QSAR) of tropinyl and piperidinyl esters.
Chemical & pharmaceutical bulletin 1998;46(2):231-41.
1998: Lim B C; Sim M K
Actions of des-Asp angiotensin I on the aortic rings of the normo- and hypertensive rats.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1998;20(1):105-17.
1998: Sim M K; Lim S L
Angiotensin AT1 receptor subtypes in the rabbit pulmonary artery. A ligand binding study.
Receptors & channels 1998;5(6):323-9.
1997: Tang F R; Sim M K
Expression of glutamate receptor subunits 2/3 and 4 in the hypoglossal nucleus of the rat after neurectomy.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1997;117(3):453-6.
1997: Sim M K; Lim B C
Determination of aminopeptidase X activity in tissues of normo- and hypertensive rats by capillary electrophoresis.
Journal of chromatography. B, Biomedical sciences and applications 1997;697(1-2):259-62.
1997: Tang F R; Sim M K
Metabotropic glutamate receptor subtype-1 alpha (mGluR1 alpha) immunoreactivity in ependymal cells of the rat caudal medulla oblongata and spinal cord.
Neuroscience letters 1997;225(3):177-80.
1997: Xu C L; Sim M K
Effect of oral feeding of essence of chicken on the level of 5-hydroxyindole acetic acid in the cerebrospinal fluid of the rat.
International journal of food sciences and nutrition 1997;48(2):113-7.
1996: Sim M K; Chai S K
Subtypes of losartan-sensitive angiotensin receptor in the rabbit pulmonary artery.
British journal of pharmacology 1996;117(7):1504-6.
1995: Radhakrishnan R; Sim M K
Actions of D-amino acid-substituted analogues of des-Asp-angiotensin I on the central pressor action of angiotensin III.
European journal of pharmacology 1995;294(1):337-9.
1995: Xu C L; Sim M K
Reduction of dihydroxyphenylacetic acid by a novel enzyme in the rat brain.
Biochemical pharmacology 1995;50(9):1333-7.
1995: Sim M K; Soh K S
Effects of des-Asp-angiotensin I on the electrically stimulated contraction of the rabbit pulmonary artery.
European journal of pharmacology 1995;284(1-2):215-9.
1995: Sim M K; Yuan H T
Effects of des-Asp-angiotensin I on the contractile action of angiotensin II and angiotensin III.
European journal of pharmacology 1995;278(2):175-8.
1994: Sim M K; Choo M H; Qiu X S
Degradation of angiotensin I to [des-Asp1]angiotensin I by a novel aminopeptidase in the rat hypothalamus.
Biochemical pharmacology 1994;48(5):1043-6.
1994: Sim M K; Qiu X S
Formation of des-Asp-angiotensin I in the hypothalamic extract of normo- and hypertensive rats.
Blood pressure 1994;3(4):260-4.
1994: Radhakrishnan R; Sim M K
Enhanced pressor response to angiotensin III in spontaneously hypertensive rats: effects of losartan.
European journal of pharmacology 1994;259(1):87-90.
1994: Sim M K; Radhakrishnan R
Novel central action of des-Asp-angiotensin I.
European journal of pharmacology 1994;257(1-2):R1-3.
1994: Sim M K; Radhakrishnan R
In vivo study of angiotensin II tachyphylaxis in freely moving normo- and hypertensive rats.
Pharmacology & toxicology 1994;74(4-5):223-7.
1994: Lim B C; Sim M K
Determination of angiotensins by capillary electrophoresis.
Journal of chromatography. B, Biomedical applications 1994;655(1):127-31.
1994: Sim M K; Radhakrishnan R
Effect of pentobarbital and chlordiazepoxide on the central pressor action of angiotensins in normo- and hypertensive rats.
European journal of pharmacology 1994;253(1-2):171-4.
1994: Parhar I S; Sim M K
Central dopaminergic neurons in tilapia: effects of gonadectomy and hypothalamic lesion.
Neuroscience research 1994;18(4):255-66.
1993: Sim M K
Degradation of angiotensin I in the endothelium and smooth muscle of the rat aorta.
Biochemical pharmacology 1993;45(7):1524-7.
1993: Kuttan S C; Sim M K
Angiotensin II-induced tachyphylaxis in aortas of normo- and hypertensive rats: changes in receptor affinity.
European journal of pharmacology 1993;232(2-3):173-80.
1993: Sim M K; Manjeet S
Muscarinic receptors in the aortae of normo- and hypertensive rats: a binding study.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1993;15(2):409-21.
1993: Kuttan S C; Sim M K
Actions of norepinephrine and angiotensin II on aortic rings of adult and aged normotensive and hypertensive rats.
Journal of cardiovascular pharmacology 1993;21(3):371-5.
1992: Sim M K; Lim S E
Discovery of a novel soluble form of monoamine oxidase in the rat brain.
Biochemical pharmacology 1992;43(6):1181-4.
1992: Sim M K; Kuttan S C
Effects of noradrenaline and prostaglandin F2 alpha on angiotensin-induced contraction and tachyphylaxis in rat aortic rings.
Pharmacology & toxicology 1992;70(1):60-4.
1992: Manjeet S; Sim M K
Muscarinic receptors in the aortae of normo- and hypertensive rats.
Japanese journal of pharmacology 1992;58 Suppl 2():357P.
1992: Sim M K; Lim B C
Scopolamine-sensitive endothelial muscarinic receptors.
Japanese journal of pharmacology 1992;58 Suppl 2():356P.
1992: Sim M K; Chan C S
Effect of experimentally-induced hypertension on angiotensin converting enzyme activity in the aortic endothelium and smooth muscle cum adventitia of the Sprague Dawley rat.
Life sciences 1992;50(23):1821-5.
1991: Kuttan S C; Sim M K
Endothelium-dependent response of the rabbit aorta to femtomolar concentrations of angiotensin II.
Journal of cardiovascular pharmacology 1991;17(6):929-34.
1991: Sim M K
Central monoamine oxidase and phenolsulfotransferase activities in spontaneously hypertensive rats.
Life sciences 1991;48(20):1985-90.
1990: Sim M K; Manjeet S
Properties of muscarinic receptors mediating second messenger responses in the rabbit aorta.
European journal of pharmacology 1990;189(6):399-404.
1990: Sim M K; Hsu T P
Sensitive assays for the determination of monoamine oxidase and phenol sulphotransferase activity in small tissue samples.
Journal of pharmacological methods 1990;24(3):157-63.
1990: Sim M K; Hsu T P
Levels of dopamine and 3,4-dihydroxyphenylacetic acid in the adenohypophysis of normo- and hypertensive rats.
Clinical and experimental hypertension. Part A, Theory and practice 1990;12(3):343-53.
1990: Mok J S; Hutchinson J S; Sim M K
Effects of dopamine on blood pressure and heart rate after microinjection into the hypothalamus of spontaneously hypertensive and normotensive Wistar-Kyoto rats.
Clinical and experimental hypertension. Part A, Theory and practice 1990;12(1):15-36.
1990: Sim M K
Angiotensin converting enzyme in the endothelium and smooth muscle cum adventitia of the normo- and hypertensive rat aorta.
Clinical and experimental hypertension. Part A, Theory and practice 1990;12(6):1107-13.
1989: Manjeet S; Sim M K
Atropine- and scopolamine-resistant subtypes of muscarinic receptors in the rabbit aorta.
European journal of pharmacology 1989;174(1):99-105.
1989: Sim M K; Chua M E
EEG in anaesthetized rats.
Pharmacology & toxicology 1989;65(2):119-20.
1989: Sim M K; Manjeet S
Endothelial muscarinic receptors in the rabbit aorta.
European journal of pharmacology 1989;163(2-3):399-400.
1988: Sim M K
Tuberoinfundibular transport of intrahypothalamic-administered dopamine in normo- and hypertensive rats.
Clinical and experimental hypertension. Part A, Theory and practice 1988;10(6):1023-30.
1987: Mok J S; Sim M K
The actions of dopamine on the blood pressure and heart rate of conscious hypertensive rats: evidence for reduced dopaminergic activity in rats of the Japanese strains.
Clinical and experimental hypertension. Part A, Theory and practice 1987;9(10):1615-35.
1987: Manjeet S; Sim M K
Decreased Na+K+ATPase activity in the aortic endothelium and smooth muscle of the spontaneously hypertensive rats.
Clinical and experimental hypertension. Part A, Theory and practice 1987;9(4):797-812.
1987: Sim M K; Chua M E
Angiotensin converting enzyme activity in strains of normo- and hypertensive rats.
Clinical and experimental hypertension. Part A, Theory and practice 1987;9(11):1763-70.
1986: Sim M K; Hutchinson J S; Chua M E
Effects of captopril on the sleep EEG of spontaneously hypertensive rats.
Clinical and experimental pharmacology & physiology 1986;13(3):259-63.
1986: Sim M K; Chua M E
Inhibition of acetylcholinesterase by various opioids.
Clinical and experimental pharmacology & physiology 1986;13(2):159-62.
1985: Sim M K; Chua M E
Altered responsiveness of the aorta of hypertensive rats to histamine and acetylcholine.
Japanese journal of pharmacology 1985;39(4):551-3.

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