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Amy Simcoe

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Physiology

Chemicals & Drugs

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Publications

TOP 3
Jay A Grobler; Geethanjali Dornadula; Michele R Rice; Amy L Simcoe; Daria J Hazuda; Michael D Miller
HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitro.
Zhijian Lu; Joann Bohn; Thomas A Rano; Carrie A Rutkowski; Amy L Simcoe; David B Olsen; William A Schleif; Anthony Carella; Lori Gabryelski; Lixia Jin; Jiunn H Lin; Emilio A Emini; Kevin Chapman; James R Tata
Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus.
Steven W Ludmerer; Donald J Graham; Evelyn Boots; Edward M Murray; Amy L Simcoe; Eric J Markel; Jay A Grobler; Osvaldo A Flores; David B Olsen; Daria J Hazuda; Robert L LaFemina
Replication fitness and NS5B drug sensitivity of diverse hepatitis C virus isolates characterized by using a transient replication assay.

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All Publications

2007: Jay A Grobler; Geethanjali Dornadula; Michele R Rice; Amy L Simcoe; Daria J Hazuda; Michael D Miller
HIV-1 reverse transcriptase plus-strand initiation exhibits preferential sensitivity to non-nucleoside reverse transcriptase inhibitors in vitro.
The Journal of biological chemistry 2007;282(11):8005-10.
2005: Zhijian Lu; Joann Bohn; Thomas A Rano; Carrie A Rutkowski; Amy L Simcoe; David B Olsen; William A Schleif; Anthony Carella; Lori Gabryelski; Lixia Jin; Jiunn H Lin; Emilio A Emini; Kevin Chapman; James R Tata
Orally bioavailable highly potent HIV protease inhibitors against PI-resistant virus.
Bioorganic & medicinal chemistry letters 2005;15(23):5311-4.
2005: Steven W Ludmerer; Donald J Graham; Evelyn Boots; Edward M Murray; Amy L Simcoe; Eric J Markel; Jay A Grobler; Osvaldo A Flores; David B Olsen; Daria J Hazuda; Robert L LaFemina
Replication fitness and NS5B drug sensitivity of diverse hepatitis C virus isolates characterized by using a transient replication assay.
Antimicrobial agents and chemotherapy 2005;49(5):2059-69.
2003: Zhijian Lu; Subharekha Raghavan; Joann Bohn; Mark Charest; Mark Stahlhut; Carrie A Rutkowski; Amy L Simcoe; David B Olsen; William A Schleif; Anthony Carella; Lori Gabryelski; Lixia Jin; Jiunn H Lin; Emilio A Emini; Kevin Chapman; James R Tata
Design and synthesis of highly potent HIV protease inhibitors with activity against resistant virus.
Bioorganic & medicinal chemistry letters 2003;13(10):1821-4.
2003: Jay A Grobler; Eric J Markel; John F Fay; Donald J Graham; Amy L Simcoe; Steven W Ludmerer; Edward M Murray; Giovanni Migliaccio; Osvaldo A Flores
Identification of a key determinant of hepatitis C virus cell culture adaptation in domain II of NS3 helicase.
The Journal of biological chemistry 2003;278(19):16741-6.
2003: Steven S Carroll; Joanne E Tomassini; Michele Bosserman; Krista Getty; Mark Stahlhut; Anne B Eldrup; Balkrishen Bhat; Dawn Hall; Amy L Simcoe; Robert L LaFemina; Carrie A Rutkowski; Bohdan Wolanski; Zhucheng Yang; Giovanni Migliaccio; Raffaele De Francesco; Lawrence C Kuo; Malcolm MacCoss; David B Olsen
Inhibition of hepatitis C virus RNA replication by 2'-modified nucleoside analogs.
The Journal of biological chemistry 2003;278(14):11979-84.