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Diane Simeone

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Ethan V Abel; Diane M Simeone
Biology and clinical applications of pancreatic cancer stem cells.
Judy C Pang; Richard S Kwon; Rebecca M Minter; Diane M Simeone; Michael H Roh
The role of cytology in the preoperative assessment and management of patients with pancreaticobiliary tract neoplasms.
Erica Proctor; Meghna Waghray; Malica Yalamanchili; Filip Bednar; David G Heidt; Cheong Jun Lee; Chenwei Li; Diane M Simeone
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.

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All Publications

2013: Ethan V Abel; Diane M Simeone
Biology and clinical applications of pancreatic cancer stem cells.
Gastroenterology 2013;144(6):1241-8.
2013: Judy C Pang; Richard S Kwon; Rebecca M Minter; Diane M Simeone; Michael H Roh
The role of cytology in the preoperative assessment and management of patients with pancreaticobiliary tract neoplasms.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2013;17(3):501-10.
2013: Erica Proctor; Meghna Waghray; Malica Yalamanchili; Filip Bednar; David G Heidt; Cheong Jun Lee; Chenwei Li; Diane M Simeone
Bmi1 enhances tumorigenicity and cancer stem cell function in pancreatic adenocarcinoma.
PloS one 2013;8(2):e55820.
2012: Edgar Ben-Josef; Isaac R Francis; Scott W Hadley; Gazala Khan; Theodore S Lawrence; William Leslie; Daniel Normolle; Matthew Schipper; Diane M Simeone; Christopher J Sonnenday; Randall TenHaken; Ross Abrams; Mark M Zalupski
A phase I/II trial of intensity modulated radiation (IMRT) dose escalation with concurrent fixed-dose rate gemcitabine (FDR-G) in patients with unresectable pancreatic cancer.
International journal of radiation oncology, biology, physics 2012;84(5):1166-71.
2012: Wan-Ching Yen; V Pete Yeung; Lucia Beviglia; Marcus M Fischer; Austin Gurney; Mark Hynes; Ann M Kapoun; Edward Kim; John Lewicki; Diane M Simeone; Xiaomei Song; Jingjiang Wu; Timothy Hoey
Anti-DLL4 has broad spectrum activity in pancreatic cancer dependent on targeting DLL4-Notch signaling in both tumor and vasculature cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2012;18(19):5374-86.
2012: Mohamad El-Zaatari; Gail Kelsey; Jamie Lee; Caitlyn M Plonka; Diane M Simeone; Arthur Tessier; Lisa A Travnikar; Michelle A Anderson; Esperanza F Cantu; Stephanie Daignault; Juanita L Merchant
Plasma Shh levels reduced in pancreatic cancer patients.
Pancreas 2012;41(7):1019-28.
2012: Chandan Kumar; Iris Wei; Diane M Simeone
Emerging frontiers in pancreatic cancer research: elaboration of key genes, cells and the extracellular milieu.
Current opinion in gastroenterology 2012;28(5):516-22.
2012: Venkatasubbaiah A Venkatesha; Sonya D Zabludoff; Lili Zhao; Theodore S Lawrence; Jonathan Maybaum; Joshua D Parsels; Leslie A Parsels; Diane M Simeone; Meredith A Morgan
Sensitization of pancreatic cancer stem cells to gemcitabine by Chk1 inhibition.
Neoplasia (New York, N.Y.) 2012;14(6):519-25.
2012: Katie Partyka; Diane M Simeone; Peter Allen; Randall Brand; Richard S Kwon; Kevin A Maupin; Mitchell McDonald; Brian B Haab
Comparison of surgical and endoscopic sample collection for pancreatic cyst fluid biomarker identification.
Journal of proteome research 2012;11(5):2904-11.
2012: Jianhui Zhu; Diane M Simeone; Jintang He; Yashu Liu; David M Lubman
Identification of glycoprotein markers for pancreatic cancer CD24+CD44+ stem-like cells using nano-LC-MS/MS and tissue microarray.
Journal of proteome research 2012;11(4):2272-81.
2012: Filip Bednar; Diane M Simeone
Metformin and cancer stem cells: old drug, new targets.
Cancer prevention research (Philadelphia, Pa.) 2012;5(3):351-4.
2012: Rebecca M Minter; Diane M Simeone
Contemporary management of nonfunctioning pancreatic neuroendocrine tumors.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2012;16(2):435-46.
2012: Andrew D Boyd; Doris Brown; Janet Hampton; Chris Henrickson; Diane M Simeone; Jeremy M G Taylor; Mark M Zalupski; Bin Zhu; Farideh Almani; Roseanne Armitage; Edgar Ben-Josef; Michelle B Riba
Screening for depression, sleep-related disturbances, and anxiety in patients with adenocarcinoma of the pancreas: a preliminary study.
TheScientificWorldJournal 2012;2012():650707.
2011: Filip Bednar; Diane M Simeone
Pancreatic cancer stem cell biology and its therapeutic implications.
Journal of gastroenterology 2011;46(12):1345-52.
2011: Chenwei Li; Marina Pasca di Magliano; Bedabrata Sarkar; Joseph Dosch; Mark Hynes; Theodore H Welling III; Jing-Jiang Wu; Diane M Simeone
c-Met is a marker of pancreatic cancer stem cells and therapeutic target.
Gastroenterology 2011;141(6):2218-2227.e5.
2011: Diane M Simeone
2011 American Pancreatic Association presidential address: demystifying the pancreas.
Pancreas 2011;40(8):1163-4.
2011: Edward J Kim; Diane M Simeone
Advances in pancreatic cancer.
Current opinion in gastroenterology 2011;27(5):460-6.
2011: Chen Li; Michelle A Anderson; John M Casper; Michael C Mullenix; Diane M Simeone; Ian M Thompson; Eugene Zolotarevsky; David M Lubman
A multiplexed bead assay for profiling glycosylation patterns on serum protein biomarkers of pancreatic cancer.
Electrophoresis 2011;32(15):2028-35.
2011: Leslie A Parsels; Yushen Qian; Daria M Tanska; Marisa Gross; Lili Zhao; Maria C Hassan; Sankari Arumugarajah; Joshua D Parsels; Linda Hylander-Gans; Diane M Simeone; Deborah Morosini; Jeffrey L Brown; Sonya D Zabludoff; Jonathan Maybaum; Theodore S Lawrence; Meredith A Morgan
Assessment of chk1 phosphorylation as a pharmacodynamic biomarker of chk1 inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(11):3706-15.
2011: Zhenxin Lin; Diane M Simeone; Michelle A Anderson; Randall E Brand; Xiaolei Xie; Kerby Shedden; Mack T Ruffin; David M Lubman
Mass spectrometric assay for analysis of haptoglobin fucosylation in pancreatic cancer.
Journal of proteome research 2011;10(5):2602-11.
2011: Ying Zhuge; Joyce Kaufman; Diane M Simeone; Herbert Chen; Omaida Velazquez
Is there still a glass ceiling for women in academic surgery?
Annals of surgery 2011;253(4):637-43.
2011: Tingting Yue; Kevin A Maupin; Brian Fallon; Michelle A Anderson; Ziding Feng; Herbert Zeh; Randall E Brand; Katie Partyka; Diane M Simeone; Karen Kaul; Dean E Brenner; A James Moser; Lin Li; Brian B Haab
Enhanced discrimination of malignant from benign pancreatic disease by measuring the CA 19-9 antigen on specific protein carriers.
PloS one 2011;6(12):e29180.
2011: Richard S Kwon; Diane M Simeone
The use of protein-based biomarkers for the diagnosis of cystic tumors of the pancreas.
International journal of proteomics 2011;2011():413646.
2010: Robert H Wilson; Malavika Chandra; Leng-Chun Chen; William R Lloyd; James M Scheiman; Diane M Simeone; Julianne Purdy; Barbara J McKenna; Mary-Ann Mycek
Photon-tissue interaction model enables quantitative optical analysis of human pancreatic tissues.
Optics express 2010;18(21):21612-21.
2010: Michelle A Anderson; Dean E Brenner; James M Scheiman; Diane M Simeone; Nalina Singh; Matthew J Sikora; Lili Zhao; Amy N Mertens; James M Rae
Reliable gene expression measurements from fine needle aspirates of pancreatic tumors: effect of amplicon length and quality assessment.
The Journal of molecular diagnostics : JMD 2010;12(5):566-75.
2010: Tasneem Patwa; Chen Li; Diane M Simeone; David M Lubman
Glycoprotein analysis using protein microarrays and mass spectrometry.
Mass spectrometry reviews 2010;29(5):830-44.
2010: Baskaran Sundaram; J B Robbins; M D Zeglis; James M Scheiman; Diane M Simeone; Isaac R Francis
Mesenteric venous collateral vessels mimicking cystic pancreatic neoplasm.
The British journal of radiology 2010;83(992):e175-8.
2010: Lan Dai; Chen Li; Kerby Shedden; Cheong J Lee; Chenwei Li; HuyVuong Quoc; Diane M Simeone; David M Lubman
Quantitative proteomic profiling studies of pancreatic cancer stem cells.
Journal of proteome research 2010;9(7):3394-402.
2010: Meredith A Morgan; Leslie A Parsels; Lili Zhao; Joshua D Parsels; Mary A Davis; Maria C Hassan; Sankari Arumugarajah; Linda Hylander-Gans; Deborah Morosini; Diane M Simeone; Shilpy Sharma; Daniel Normolle; Sonya D Zabludoff; Jonathan Maybaum; Theodore S Lawrence
Mechanism of radiosensitization by the Chk1/2 inhibitor AZD7762 involves abrogation of the G2 checkpoint and inhibition of homologous recombinational DNA repair.
Cancer research 2010;70(12):4972-81.
2010: Brian B Haab; Andrew Porter; Tingting Yue; Lin Li; James M Scheiman; Michelle A Anderson; Dawn Barnes; C Max Schmidt; Ziding Feng; Diane M Simeone
Glycosylation variants of mucins and CEACAMs as candidate biomarkers for the diagnosis of pancreatic cystic neoplasms.
Annals of surgery 2010;251(5):937-45.
2010: Gazala N Khan; Marina Pasca di Magliano; Diane M Simeone
New frontiers in pancreatic cancer research.
Surgical oncology clinics of North America 2010;19(2):431-51.
2010: Chen Li; Hye-Yeung Kim; Huy Vuong; Tasneem Patwa; Manoj Pal; Randall E Brand; Diane M Simeone; David M Lubman
The identification of auto-antibodies in pancreatic cancer patient sera using a naturally fractionated Panc-1 cell line.
Cancer biomarkers : section A of Disease markers 2010;7(1):25-37.
2010: Cheong J Lee; Aaron C Spalding; Edgar Ben-Josef; Lidong Wang; Diane M Simeone
In vivo bioluminescent imaging of irradiated orthotopic pancreatic cancer xenografts in nonobese diabetic-severe combined immunodeficient mice: a novel method for targeting and assaying efficacy of ionizing radiation.
Translational oncology 2010;3(3):153-9.
2010: Joseph S Dosch; Marina Pasca di Magliano; Diane M Simeone
Pancreatic cancer and hedgehog pathway signaling: new insights.
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] 2010;10(2-3):151-7.
2010: Malavika Chandra; James M Scheiman; Diane M Simeone; Barbara J McKenna; Julianne Purdy; Mary-Ann Mycek
Spectral areas and ratios classifier algorithm for pancreatic tissue classification using optical spectroscopy.
Journal of biomedical optics 2010;15(1):010514.
2010: Nonthalee Pausawasdi; David G Heidt; Richard S Kwon; Diane M Simeone; James M Scheiman
Long-term follow-up of patients with incidentally discovered pancreatic cystic neoplasms evaluated by endoscopic ultrasound.
Surgery 2010;147(1):13-20.
2009: Sameer Desai; Edgar Ben-Josef; Kent Andrew Griffith; Diane M Simeone; Joel K Greenson; Isaac R Francis; Janet Hampton; Lisa M Colletti; Alfred E Chang; Theodore S Lawrence; Mark M Zalupski
Gemcitabine-based combination chemotherapy followed by radiation with capecitabine as adjuvant therapy for resected pancreas cancer.
International journal of radiation oncology, biology, physics 2009;75(5):1450-5.
2009: Philip A Philip; Margaret Mooney; Deborah Jaffe; Gail Eckhardt; Malcolm Moore; Neal J Meropol; Leisha A Emens; Eileen O'Reilly; Murray Korc; Lee Ellis; Jacqueline Benedetti; Mace Rothenberg; Christopher Willett; Margaret Tempero; Andrew Lowy; James Abbruzzese; Diane M Simeone; Sunil Hingorani; Jordan Berlin; Joel E Tepper
Consensus report of the national cancer institute clinical trials planning meeting on pancreas cancer treatment.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2009;27(33):5660-9.
2009: Robert H Wilson; Malavika Chandra; James M Scheiman; Diane M Simeone; Barbara J McKenna; Julianne Purdy; Mary-Ann Mycek
Optical spectroscopy detects histological hallmarks of pancreatic cancer.
Optics express 2009;17(20):17502-16.
2009: Randall E Brand; Julia B Greer; Eugene Zolotarevsky; Rhonda Brand; Hongyan Du; Diane M Simeone; Anna Zisman; Addi Gorchow; Shih-Yuan Connie Lee; Hemant K Roy; Michelle A Anderson
Pancreatic cancer patients who smoke and drink are diagnosed at younger ages.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2009;7(9):1007-12.
2009: Ilona Kryczek; Mousumi Banerjee; Pui Cheng; Linhua Vatan; Wojciech Szeliga; Shuang Wei; Emina Huang; Emily Finlayson; Diane M Simeone; Theodore H Welling III; Alfred E Chang; George Coukos; J Rebecca Liu; Weiping Zou
Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments.
Blood 2009;114(6):1141-9.
2009: Diane M Simeone
The evolution of the SUS.
Surgery 2009;146(2):131-7.
2009: Bedabrata Sarkar; Joseph Dosch; Diane M Simeone
Cancer stem cells: a new theory regarding a timeless disease.
Chemical reviews 2009;109(7):3200-8.
2009: Tasneem H Patwa; Chen Li; Laila M Poisson; Hye-Yeung Kim; Manoj Pal; Debashis Ghosh; Diane M Simeone; David M Lubman
The identification of phosphoglycerate kinase-1 and histone H4 autoantibodies in pancreatic cancer patient serum using a natural protein microarray.
Electrophoresis 2009;30(12):2215-26.
2009: Ilona Kryczek; J Rebecca Liu; Guobin Wang; Ke Wu; Xiaogong Shu; Wojciech Szeliga; Linhua Vatan; Emily Virginia Anne Finlayson; Emina Huang; Diane M Simeone; Bruce G Redman; Theodore H Welling III; Alfred E Chang; Weiping Zou
FOXP3 defines regulatory T cells in human tumor and autoimmune disease.
Cancer research 2009;69(9):3995-4000.
2009: Filip Bednar; Diane M Simeone
Pancreatic cancer stem cells and relevance to cancer treatments.
Journal of cellular biochemistry 2009;107(1):40-5.
2009: Lidong Wang; David G Heidt; Cheong J Lee; Huibin Yang; Craig D Logsdon; Lizhi Zhang; Eric R Fearon; Mats Ljungman; Diane M Simeone
Oncogenic function of ATDC in pancreatic cancer through Wnt pathway activation and beta-catenin stabilization.
Cancer cell 2009;15(3):207-19.
2009: Chen Li; Diane M Simeone; Dean E Brenner; Michelle A Anderson; Kerby Shedden; Mack T Ruffin; David M Lubman
Pancreatic cancer serum detection using a lectin/glyco-antibody array method.
Journal of proteome research 2009;8(2):483-92.
2009: Chenwei Li; C J Lee; Diane M Simeone
Identification of human pancreatic cancer stem cells.
Methods in molecular biology (Clifton, N.J.) 2009;568():161-73.
2009: Tasneem H Patwa; Yinghua Qiu; Jia Zhao; Diane M Simeone; David M Lubman
All-liquid separations, protein microarrays, and mass spectrometry to interrogate serum proteomes: an application to serum glycoproteomics.
Methods in molecular biology (Clifton, N.J.) 2009;520():75-87.
2008: Jia Zhao; Tasneem H Patwa; David M Lubman; Diane M Simeone
Protein biomarkers in cancer: natural glycoprotein microarray approaches.
Current opinion in molecular therapeutics 2008;10(6):602-10.
2008: Diane M Simeone
Pancreatic cancer stem cells: implications for the treatment of pancreatic cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(18):5646-8.
2008: Tobias Grote; Doris R Siwak; Herbert A Fritsche; Corwin Joy; Gordon B Mills; Diane M Simeone; david whitcomb; Craig D Logsdon
Validation of reverse phase protein array for practical screening of potential biomarkers in serum and plasma: accurate detection of CA19-9 levels in pancreatic cancer.
Proteomics 2008;8(15):3051-60.
2008: Diane M Simeone
SSAT/AGA/ASGE state of the art conference on cystic neoplasms of the pancreas.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2008;12(8):1475-7.
2008: Huibin Yang; Cheong J Lee; Lizhi Zhang; Maria Dolors Sans; Diane M Simeone
Regulation of transforming growth factor beta-induced responses by protein kinase A in pancreatic acinar cells.
American journal of physiology. Gastrointestinal and liver physiology 2008;295(1):G170-G178.
2008: Cheong J Lee; Joseph Dosch; Diane M Simeone
Pancreatic cancer stem cells.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(17):2806-12.
2008: Tasneem H Patwa; Yanfei Wang; Diane M Simeone; David M Lubman
Enhanced detection of autoantibodies on protein microarrays using a modified protein digestion technique.
Journal of proteome research 2008;7(6):2553-61.
2008: Christopher J Sonnenday; Diane M Simeone
"Criminal" profiling of the pancreas: when is aggressive therapy indicated for a non-aggressive entity?
Annals of surgery 2008;247(4):580-2.
2008: Cheong J Lee; Chenwei Li; Diane M Simeone
Human pancreatic cancer stem cells: implications for how we treat pancreatic cancer.
Translational oncology 2008;1(1):14-8.
2008: C J Lee; James M Scheiman; Michelle A Anderson; O J Hines; H A Reber; James Farrell; Michael L Kochman; P J Foley; J Drebin; Y S Oh; Gregory Ginsberg; N Ahmad; N B Merchant; J Isbell; A A Parikh; J B Stokes; T Bauer; R B Adams; Diane M Simeone
Risk of malignancy in resected cystic tumors of the pancreas < or =3 cm in size: is it safe to observe asymptomatic patients? A multi-institutional report.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2008;12(2):234-42.
2007: Malavika Chandra; James M Scheiman; David Heidt; Diane M Simeone; Barbara J McKenna; Mary-Ann Mycek
Probing pancreatic disease using tissue optical spectroscopy.
Journal of biomedical optics 2007;12(6):060501.
2007: David E Misek; Tasneem H Patwa; David M Lubman; Diane M Simeone
Early detection and biomarkers in pancreatic cancer.
Journal of the National Comprehensive Cancer Network : JNCCN 2007;5(10):1034-41.
2007: Sameer P Desai; Edgar Ben-Josef; Daniel Normolle; Isaac R Francis; Joel K Greenson; Diane M Simeone; Alfred E Chang; Lisa M Colletti; Theodore S Lawrence; Mark M Zalupski
Phase I study of oxaliplatin, full-dose gemcitabine, and concurrent radiation therapy in pancreatic cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2007;25(29):4587-92.
2007: Jianzhong Chen; Michelle A Anderson; David E Misek; Diane M Simeone; David M Lubman
Characterization of apolipoprotein and apolipoprotein precursors in pancreatic cancer serum samples via two-dimensional liquid chromatography and mass spectrometry.
Journal of chromatography. A 2007;1162(2):117-25.
2007: Piero Dalerba; Scott J Dylla; In-Kyung Park; Rui Liu; Xinhao Wang; Robert W Cho; Timothy Hoey; Austin Gurney; Emina H Huang; Diane M Simeone; Andrew A Shelton; Giorgio Parmiani; Chiara Castelli; Michael F Clarke
Phenotypic characterization of human colorectal cancer stem cells.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(24):10158-63.
2007: Diane M Simeone; Baoan Ji; Mousumi Banerjee; Thiruvengadam Arumugam; Dawei Li; Michelle A Anderson; Ann Marie Bamberger; Joel K Greenson; Randal E Brand; Vijaya Ramachandran; Craig D Logsdon
CEACAM1, a novel serum biomarker for pancreatic cancer.
Pancreas 2007;34(4):436-43.
2007: Jia Zhao; Tasneem H Patwa; Weilian Qiu; Kerby Shedden; Robert Hinderer; David E Misek; Michelle A Anderson; Diane M Simeone; David M Lubman
Glycoprotein microarrays with multi-lectin detection: unique lectin binding patterns as a tool for classifying normal, chronic pancreatitis and pancreatic cancer sera.
Journal of proteome research 2007;6(5):1864-74.
2007: Songming Chen; Tom LaRoche; Darren Hamelinck; Derek Bergsma; Dean E Brenner; Diane M Simeone; Randall E Brand; Brian B Haab
Multiplexed analysis of glycan variation on native proteins captured by antibody microarrays.
Nature methods 2007;4(5):437-44.
2007: Emina H Huang; David G Heidt; Chen-Wei Li; Diane M Simeone
Cancer stem cells: a new paradigm for understanding tumor progression and therapeutic resistance.
Surgery 2007;141(4):415-9.
2007: Vijaya Ramachandran; Thiruvengadam Arumugam; Rosa F Hwang; Joel K Greenson; Diane M Simeone; Craig D Logsdon
Adrenomedullin is expressed in pancreatic cancer and stimulates cell proliferation and invasion in an autocrine manner via the adrenomedullin receptor, ADMR.
Cancer research 2007;67(6):2666-75.
2007: Jia Zhao; Weilian Qiu; Diane M Simeone; David M Lubman
N-linked glycosylation profiling of pancreatic cancer serum using capillary liquid phase separation coupled with mass spectrometric analysis.
Journal of proteome research 2007;6(3):1126-38.
2007: David G Heidt; Charles F Burant; Diane M Simeone
Total pancreatectomy: indications, operative technique, and postoperative sequelae.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2007;11(2):209-16.
2007: Chenwei Li; David G Heidt; Piero Dalerba; Charles F Burant; Lanjing Zhang; Volkan Adsay; Max S Wicha; Michael F Clarke; Diane M Simeone
Identification of pancreatic cancer stem cells.
Cancer research 2007;67(3):1030-7.
2006: Diane M Simeone; Lizhi Zhang; Mary K Treutelaar; Lanjing Zhang; Kathleen Graziano; Craig D Logsdon; Charles F Burant
Islet hypertrophy following pancreatic disruption of Smad4 signaling.
American journal of physiology. Endocrinology and metabolism 2006;291(6):E1305-16.
2006: Tasneem H Patwa; Jia Zhao; Michelle A Anderson; Diane M Simeone; David M Lubman
Screening of glycosylation patterns in serum using natural glycoprotein microarrays and multi-lectin fluorescence detection.
Analytical chemistry 2006;78(18):6411-21.
2006: Chul Yoo; Jia Zhao; Manoj Pal; Katherine Hersberger; Christian G. Huber; Diane M Simeone; David G Beer; David M Lubman
Automated integration of monolith-based protein separation with on-plate digestion for mass spectrometric analysis of esophageal adenocarcinoma human epithelial samples.
Electrophoresis 2006;27(18):3643-51.
2006: Jia Zhao; Diane M Simeone; David G Heidt; Michelle A Anderson; David M Lubman
Comparative serum glycoproteomics using lectin selected sialic acid glycoproteins with mass spectrometric analysis: application to pancreatic cancer serum.
Journal of proteome research 2006;5(7):1792-802.
2006: Erika A Newman; Diane M Simeone; Michael W Mulholland
Adjuvant treatment strategies for pancreatic cancer.
Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract 2006;10(6):916-26.
2006: Lizhi Zhang; Li Chenwei; Redah Mahmood; Kenneth L van Golen; Joel K Greenson; Gangyong Li; Nisha J D'Silva; Xiangquan Li; Charles F Burant; Craig D Logsdon; Diane M Simeone
Identification of a putative tumor suppressor gene Rap1GAP in pancreatic cancer.
Cancer research 2006;66(2):898-906.
2005: Thiruvengadam Arumugam; Diane M Simeone; Kenneth L van Golen; Craig D Logsdon
S100P promotes pancreatic cancer growth, survival, and invasion.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(15):5356-64.
2004: Charles E Binkley; Lizhi Zhang; Joel K Greenson; Thomas J Giordano; Rork Kuick; David E Misek; Samir Hanash; Craig D Logsdon; Diane M Simeone
The molecular basis of pancreatic fibrosis: common stromal gene expression in chronic pancreatitis and pancreatic adenocarcinoma.
Pancreas 2004;29(4):254-63.
2004: Lizhi Zhang; Zheng Fu; Charles E Binkley; Thomas J Giordano; Charles F Burant; Craig D Logsdon; Diane M Simeone
Raf kinase inhibitory protein inhibits beta-cell proliferation.
Surgery 2004;136(3):708-15.
2004: Su-Hyung Hong; David E Misek; Hong Wang; Eric Puravs; Thomas J Giordano; Joel K Greenson; Dean E Brenner; Diane M Simeone; Craig D Logsdon; Samir M Hanash
An autoantibody-mediated immune response to calreticulin isoforms in pancreatic cancer.
Cancer research 2004;64(15):5504-10.
2004: Jiro Okami; Diane M Simeone; Craig D Logsdon
Silencing of the hypoxia-inducible cell death protein BNIP3 in pancreatic cancer.
Cancer research 2004;64(15):5338-46.
2004: Lizhi Zhang; Chao Jun Duan; Charles E Binkley; Gangyong Li; Michael D Uhler; Craig D Logsdon; Diane M Simeone
A transforming growth factor beta-induced Smad3/Smad4 complex directly activates protein kinase A.
Molecular and cellular biology 2004;24(5):2169-80.
2004: Thiruvengadam Arumugam; Diane M Simeone; Ann Marie Schmidt; Craig D Logsdon
S100P stimulates cell proliferation and survival via receptor for activated glycation end products (RAGE).
The Journal of biological chemistry 2004;279(7):5059-65.
2004: Brian S Knipp; Gorav Ailawadi; John W Ford; David A Peterson; Matthew J Eagleton; Karen J Roelofs; Kevin K Hannawa; Michael P Deogracias; Baoan Ji; Craig D Logsdon; Kathleen Graziano; Diane M Simeone; Robert W Thompson; Peter K Henke; James C Stanley; Gilbert R Upchurch Jr
Increased MMP-9 expression and activity by aortic smooth muscle cells after nitric oxide synthase inhibition is associated with increased nuclear factor-kappaB and activator protein-1 activity.
The Journal of surgical research 2004;116(1):70-80.
2003: Kerby Shedden; Jeremy Taylor; Thomas J Giordano; Rork Kuick; David E Misek; Gad Rennert; Donald R Schwartz; Stephen B Gruber; Craig D Logsdon; Diane M Simeone; Sharon L R Kardia; Joel K Greenson; Kathleen R Cho; David G Beer; Eric R Fearon; Samir Hanash
Accurate molecular classification of human cancers based on gene expression using a simple classifier with a pathological tree-based framework.
The American journal of pathology 2003;163(5):1985-95.
2003: Mary K Treutelaar; Jennifer M Skidmore; Claudia L Dias-Leme; Manami Hara; Lizhi Zhang; Diane M Simeone; Donna M Martin; Charles F Burant
Nestin-lineage cells contribute to the microvasculature but not endocrine cells of the islet.
Diabetes 2003;52(10):2503-12.
2003: Craig D Logsdon; Diane M Simeone; Charles E Binkley; Thiruvengadam Arumugam; Joel K Greenson; Thomas J Giordano; David E Misek; Rork Kuick; Samir Hanash
Molecular profiling of pancreatic adenocarcinoma and chronic pancreatitis identifies multiple genes differentially regulated in pancreatic cancer.
Cancer research 2003;63(10):2649-57.
2002: Baoan Ji; Yan Bi; Diane M Simeone; richard mortensen; Craig D Logsdon
Human pancreatic acinar cells do not respond to cholecystokinin.
Pharmacology & toxicology 2002;91(6):327-32.
2002: Charles E Binkley; Sandro Cinti; Diane M Simeone; Lisa M Colletti
Bacillus anthracis as an agent of bioterrorism: a review emphasizing surgical treatment.
Annals of surgery 2002;236(1):9-16.
2002: Charles F Burant; Diane M Simeone
Connecting islet development and developing useful islets.
Trends in endocrinology and metabolism: TEM 2002;13(2):48-9.
2002: Xueqing Chen; Baoan Ji; Bing Han; Stephen A Ernst; Diane M Simeone; Craig D Logsdon
NF-kappaB activation in pancreas induces pancreatic and systemic inflammatory response.
Gastroenterology 2002;122(2):448-57.
2001: Baoan Ji; Yan Bi; Diane M Simeone; richard mortensen; Craig D Logsdon
Human pancreatic acinar cells lack functional responses to cholecystokinin and gastrin.
Gastroenterology 2001;121(6):1380-90.
2001: Robert A Cowles; Cheryl A Moyer; Seema S Sonnad; Diane M Simeone; James A Knol; Frederic E Eckhauser; Michael W Mulholland; Lisa M Colletti
Doctor-patient communication in surgery: attitudes and expectations of general surgery patients about the involvement and education of surgical residents.
Journal of the American College of Surgeons 2001;193(1):73-80.
2001: Diane M Simeone; Lian Zhang; Kathleen Graziano; B Nicke; T Pham; C Schaefer; Craig D Logsdon
Smad4 mediates activation of mitogen-activated protein kinases by TGF-beta in pancreatic acinar cells.
American journal of physiology. Cell physiology 2001;281(1):C311-9.
2001: Lian Zhang; Kathleen Graziano; T Pham; Craig D Logsdon; Diane M Simeone
Adenovirus-mediated gene transfer of dominant-negative Smad4 blocks TGF-beta signaling in pancreatic acinar cells.
American journal of physiology. Gastrointestinal and liver physiology 2001;280(6):G1247-53.
2001: Diane M Simeone; James M Scheiman; Norman W Thompson
The "serendipitous" surgical cure of the Zollinger-Ellison syndrome in a patient with multiple endocrine neoplasia type 1 despite an unsuspected diagnosis of either disease.
Journal of clinical gastroenterology 2001;32(3):268-71.
2000: Diane M Simeone; T Pham; Craig D Logsdon
Disruption of TGFbeta signaling pathways in human pancreatic cancer cells.
Annals of surgery 2000;232(1):73-80.
1999: Diane M Simeone; A Hassan; James M Scheiman
Giant peptic ulcer: a surgical or medical disease?
Surgery 1999;126(3):474-8.
1999: Diane M Simeone; Thomas Pranikoff
Images in clinical medicine. Mesenteric cyst.
The New England journal of medicine 1999;341(9):659.
1997: Diane M Simeone; A Cascarelli; Craig D Logsdon
Adenoviral-mediated gene transfer of a constitutively active retinoblastoma gene inhibits human pancreatic tumor cell proliferation.
Surgery 1997;122(2):428-33; discussion 433-4.
1996: J Few; Norman W Thompson; P Angelos; Diane M Simeone; Thomas J Giordano; T Reeve
Riedel's thyroiditis: treatment with tamoxifen.
Surgery 1996;120(6):993-8; discussion 998-9.
1996: AJ Michaels; S J Gerndt; Paul A Taheri; Stewart C Wang; Wendy L Wahl; Diane M Simeone; david m williams; Lazar J Greenfield; JL Rodriguez
Blunt force injury of the abdominal aorta.
The Journal of trauma 1996;41(1):105-9.
1996: Diane M Simeone; B C Kimball; Michael W Mulholland
Acetylcholine-induced calcium signaling associated with muscarinic receptor activation in cultured myenteric neurons.
Journal of the American College of Surgeons 1996;182(6):473-81.
1995: Diane M Simeone; K Sandelin; Norman W Thompson
Undescended superior parathyroid gland: a potential cause of failed cervical exploration for hyperparathyroidism.
Surgery 1995;118(6):949-56.
1995: Diane M Simeone; David I Yule; Craig D Logsdon; John Williams
Ca2+ signaling through secretagogue and growth factor receptors on pancreatic AR42J cells.
Regulatory peptides 1995;55(2):197-206.
1995: Diane M Simeone; B C Kimball; Michael W Mulholland
Bombesin-mediated calcium fluxes in myenteric plexus neurons.
Peptides 1995;16(7):1307-11.
1994: Diane M Simeone; G Romanchuk; Michael W Mulholland
Dual pathways regulate neurite outgrowth in enteric ganglia.
The American journal of physiology 1994;267(4 Pt 1):G723-9.
1994: Michael W Mulholland; G Romanchuk; K Lally; Diane M Simeone
Nerve growth factor promotes neurite outgrowth in guinea pig myenteric plexus ganglia.
The American journal of physiology 1994;267(4 Pt 1):G716-22.
1993: Michael W Mulholland; Diane M Simeone
Prostaglandin E2 stimulation of acetylcholine release from guinea pig myenteric plexus neurons.
American journal of surgery 1993;166(5):552-6.
1993: Michael W Mulholland; Diane M Simeone
Bombesin-stimulated acetylcholine release from myenteric plexus neurons.
The Journal of surgical research 1993;54(5):389-92.
1992: Michael W Mulholland; G Romanchuk; Diane M Simeone; K Flowe
Stimulation of myenteric plexus neurite outgrowth by insulin and insulin-like growth factors I and II.
Life sciences 1992;51(23):1789-96.