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Graham Simmons

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TOP 3
Yanchen Zhou; Graham Simmons
Development of novel entry inhibitors targeting emerging viruses.
Graham Simmons; William M Switzer; Ning Tang; Leslie Tobler; Jiangqin Zhao; Harvey J Alter; James Bethel; Michael P Busch; John M Coffin; Kui Gao; Simone A Glynn; John Hackett; Walid Heneine; Indira K Hewlett; Jerry A Holmberg; Mary F Kearney; Steven H Kleinman; Anthony L Komaroff; Jeffrey Linnen; Shyh-Ching Lo; Judy A Mikovits; Max A Pfost; Francis W Ruscetti
Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study.
Yanchen Zhou; Juliet Agudelo; Sean M Amberg; Yen Ting Chen; Charles S Craik; David H Goetz; Elizabeth Hansell; Kai Lu; James McKerrow; William R Roush; Graham Simmons
Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay.

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All Publications

2012: Yanchen Zhou; Graham Simmons
Development of novel entry inhibitors targeting emerging viruses.
Expert review of anti-infective therapy 2012;10(10):1129-38.
2011: Graham Simmons; William M Switzer; Ning Tang; Leslie Tobler; Jiangqin Zhao; Harvey J Alter; James Bethel; Michael P Busch; John M Coffin; Kui Gao; Simone A Glynn; John Hackett; Walid Heneine; Indira K Hewlett; Jerry A Holmberg; Mary F Kearney; Steven H Kleinman; Anthony L Komaroff; Jeffrey Linnen; Shyh-Ching Lo; Judy A Mikovits; Max A Pfost; Francis W Ruscetti
Failure to confirm XMRV/MLVs in the blood of patients with chronic fatigue syndrome: a multi-laboratory study.
Science (New York, N.Y.) 2011;334(6057):814-7.
2011: Yanchen Zhou; Juliet Agudelo; Sean M Amberg; Yen Ting Chen; Charles S Craik; David H Goetz; Elizabeth Hansell; Kai Lu; James McKerrow; William R Roush; Graham Simmons
Inhibitors of SARS-CoV entry--identification using an internally-controlled dual envelope pseudovirion assay.
Antiviral research 2011;92(2):187-94.
2011: Graham Simmons; Stephanie Bertram; Ilona Glowacka; Imke Steffen; Chawaree Chaipan; Juliet Agudelo; Kai Lu; Andrew J Rennekamp; Heike Hofmann; Paul Bates; Stefan Pöhlmann
Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion.
Virology 2011;413(2):265-74.
2011: Graham Simmons; Simone A Glynn; Jerry A Holmberg; John M Coffin; Indira K Hewlett; Shyh-Ching Lo; Judy A Mikovits; William M Switzer; Jeffrey M Linnen; Michael P Busch
The Blood Xenotropic Murine Leukemia Virus-Related Virus Scientific Research Working Group: mission, progress, and plans.
Transfusion 2011;51(3):643-53.
2010: Chawaree Chaipan; Imke Steffen; Theodros Solomon Tsegaye; Stephanie Bertram; Ilona Glowacka; Yukinari Kato; Jan Schmökel; Jan Münch; Graham Simmons; Rita Gerardy-Schahn; Stefan Pöhlmann
Incorporation of podoplanin into HIV released from HEK-293T cells, but not PBMC, is required for efficient binding to the attachment factor CLEC-2.
Retrovirology 2010;7():47.
2007: Rachel L Kaletsky; Graham Simmons; Paul Bates
Proteolysis of the Ebola virus glycoproteins enhances virus binding and infectivity.
Journal of virology 2007;81(24):13378-84.
2006: Heike Hofmann; Graham Simmons; Andrew J Rennekamp; Chawaree Chaipan; Thomas Gramberg; Elke Heck; Martina Geier; Anja Wegele; Andrea Marzi; Paul Bates; Stefan Pöhlmann
Highly conserved regions within the spike proteins of human coronaviruses 229E and NL63 determine recognition of their respective cellular receptors.
Journal of virology 2006;80(17):8639-52.
2006: Andrea Marzi; Armin Akhavan; Graham Simmons; Thomas Gramberg; Heike Hofmann; Paul Bates; Vishwanath R Lingappa; Stefan Pöhlmann
The signal peptide of the ebolavirus glycoprotein influences interaction with the cellular lectins DC-SIGN and DC-SIGNR.
Journal of virology 2006;80(13):6305-17.
2006: Zhaozhu Qiu; Susan T Hingley; Graham Simmons; Christopher Yu; Jayasri Das Sarma; Paul Bates; Susan R Weiss
Endosomal proteolysis by cathepsins is necessary for murine coronavirus mouse hepatitis virus type 2 spike-mediated entry.
Journal of virology 2006;80(12):5768-76.
2006: Graham Simmons; Andrew J Rennekamp; Paul Bates
Proteolysis of SARS-associated coronavirus spike glycoprotein.
Advances in experimental medicine and biology 2006;581():235-40.
2006: Sean M Amberg; Robert C Netter; Graham Simmons; Paul Bates
Expanded tropism and altered activation of a retroviral glycoprotein resistant to an entry inhibitor peptide.
Journal of virology 2006;80(1):353-9.
2005: Graham Simmons; Dhaval N Gosalia; Andrew J Rennekamp; Jacqueline D Reeves; Scott L Diamond; Paul Bates
Inhibitors of cathepsin L prevent severe acute respiratory syndrome coronavirus entry.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(33):11876-81.
2004: Andrea Marzi; Thomas Gramberg; Graham Simmons; Peggy Möller; Andrew J Rennekamp; Mandy Krumbiegel; Martina Geier; Jutta Eisemann; Nadine M Turza; Bertrand Saunier; Alexander Steinkasserer; Stephan Becker; Paul Bates; Heike Hofmann; Stefan Pöhlmann
DC-SIGN and DC-SIGNR interact with the glycoprotein of Marburg virus and the S protein of severe acute respiratory syndrome coronavirus.
Journal of virology 2004;78(21):12090-5.
2004: Graham Simmons; Jacqueline D Reeves; Andrew J Rennekamp; Sean M Amberg; Andrew J Piefer; Paul Bates
Characterization of severe acute respiratory syndrome-associated coronavirus (SARS-CoV) spike glycoprotein-mediated viral entry.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(12):4240-5.
2004: Graham Simmons; Anee Lee; Andrew J Rennekamp; Xin Fan; Paul Bates; Hao Shen
Identification of murine T-cell epitopes in Ebola virus nucleoprotein.
Virology 2004;318(1):224-30.
2003: Graham Simmons; Andrew J Rennekamp; Ning Chai; Luk Vandenberghe; James L Riley; Paul Bates
Folate receptor alpha and caveolae are not required for Ebola virus glycoprotein-mediated viral infection.
Journal of virology 2003;77(24):13433-8.
2003: Graham Simmons; Jacqueline D Reeves; Case C Grogan; Luk Vandenberghe; Frédéric Baribaud; J Charles Whitbeck; Emily Burke; Michael J Buchmeier; Elizabeth J Soilleux; James L Riley; Robert W Doms; Paul Bates; Stefan Pöhlmann
DC-SIGN and DC-SIGNR bind ebola glycoproteins and enhance infection of macrophages and endothelial cells.
Virology 2003;305(1):115-23.
2003: George Lin; Graham Simmons; Stefan Pöhlmann; Frédéric Baribaud; Houping Ni; George J Leslie; Beth Haggarty; Paul Bates; Drew Weissman; James A Hoxie; Robert W Doms
Differential N-linked glycosylation of human immunodeficiency virus and Ebola virus envelope glycoproteins modulates interactions with DC-SIGN and DC-SIGNR.
Journal of virology 2003;77(2):1337-46.
2002: Graham Simmons; Rouven J Wool-Lewis; Frédéric Baribaud; Robert C Netter; Paul Bates
Ebola virus glycoproteins induce global surface protein down-modulation and loss of cell adherence.
Journal of virology 2002;76(5):2518-28.