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Patricia Simon-Assmann

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TOP 3
Patricia Simon-Assmann
The laminin family: founding members of the basement membrane.
Caroline Spenlé; Gertraud Orend; Patricia Simon-Assmann; Jeffrey H Miner
Laminin α5 guides tissue patterning and organogenesis.
C Spenlé; T Hussenet; Michèle Kedinger; J Lacroute; O Lefebvre; G Orend; Patricia Simon-Assmann
Dysregulation of laminins in intestinal inflammation.

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All Publications

2013: Patricia Simon-Assmann
The laminin family: founding members of the basement membrane.
Cell adhesion & migration 2013;7(1):44-7.
2013: Caroline Spenlé; Gertraud Orend; Patricia Simon-Assmann; Jeffrey H Miner
Laminin α5 guides tissue patterning and organogenesis.
Cell adhesion & migration 2013;7(1):90-100.
2012: C Spenlé; T Hussenet; Michèle Kedinger; J Lacroute; O Lefebvre; G Orend; Patricia Simon-Assmann
Dysregulation of laminins in intestinal inflammation.
Pathologie-biologie 2012;60(1):41-7.
2012: Léa Ritié; Caroline Spenlé; Christiane Arnold; Dominique Bagnard; Anne-Laure Bolcato-Bellemin; Christine Bole-Feysot; Bernard Jost; Michèle Kedinger; Annick Klein; Joël Lacroute; Olivier Lefebvre; Gertraud Orend; Patricia Simon-Assmann
Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice.
PloS one 2012;7(5):e37710.
2011: Céline Heng; Annick Klein; Olivier Lefebvre; Gertraud Orend; Patricia Simon-Assmann; Malia M Edwards; Dominique Bagnard
Functional role of laminin α1 chain during cerebellum development.
Cell adhesion & migration 2011;5(6):480-9.
2011: Patricia Simon-Assmann; Caroline Spenlé; Elmina Mammadova-Bach; Gertraud Orend; Olivier Lefebvre
Role of laminins in physiological and pathological angiogenesis.
The International journal of developmental biology 2011;55(4-5):455-65.
2010: Malia M Edwards; Elmina Mammadova-Bach; Fabien Alpy; Annick Klein; Wanda L Hicks; Michel Roux; Patricia Simon-Assmann; Richard S Smith; Gertraud Orend; Jiang Wu; Neal S Peachey; Jürgen K Naggert; Olivier Lefebvre; Patsy M Nishina
Mutations in Lama1 disrupt retinal vascular development and inner limiting membrane formation.
The Journal of biological chemistry 2010;285(10):7697-711.
2010: Patricia Simon-Assmann; C Spenle; Olivier Lefebvre; Michèle Kedinger
The role of the basement membrane as a modulator of intestinal epithelial-mesenchymal interactions.
Progress in molecular biology and translational science 2010;96():175-206.
2010: Dirk Zboralski; Bettina Warscheid; Susanne Klein-Scory; M Bassel Malas; Heiko Becker; Miriam Böckmann; Helmut E Meyer; Wolff Schmiegel; Patricia Simon-Assmann; Irmgard Schwarte-Waldhoff
Uncoupled responses of Smad4-deficient cancer cells to TNFalpha result in secretion of monomeric laminin-gamma2.
Molecular cancer 2010;9(1):65.
2009: Patricia Simon-Assmann; Anne-Laure Bolcato-Bellemin; Annick Klein; Michèle Kedinger
Tissue recombinants to study extracellular matrix targeting to basement membranes.
Methods in molecular biology (Clifton, N.J.) 2009;522():309-18.
2008: Cécile Rahuel; Anne Filipe; Léa Ritie; Wassim El Nemer; Natacha Patey-Mariaud; Dominique Eladari; Jean-Pierre Cartron; Patricia Simon-Assmann; Caroline Le Van Kim; Yves Colin
Genetic inactivation of the laminin alpha5 chain receptor Lu/BCAM leads to kidney and intestinal abnormalities in the mouse.
American journal of physiology. Renal physiology 2008;294(2):F393-406.
2007: Patricia Simon-Assmann; Natacha Turck; M Sidhoum-Jenny; Gérard Gradwohl; Michèle Kedinger
In vitro models of intestinal epithelial cell differentiation.
Cell biology and toxicology 2007;23(4):241-56.
2006: Anders Stegmann; Morten Hansen; Yulan Wang; Janus B Larsen; Leif R Lund; Léa Ritié; Jeremy K Nicholson; Bjørn Quistorff; Patricia Simon-Assmann; Jesper T Troelsen; Jørgen Olsen
Metabolome, transcriptome, and bioinformatic cis-element analyses point to HNF-4 as a central regulator of gene expression during enterocyte differentiation.
Physiological genomics 2006;27(2):141-55.
2006: Mercè Martín; Patricia Simon-Assmann; Michèle Kedinger; Marianne Martin; Paul Mangeat; Francisco X Real; Myriam Fabre
DCC regulates cell adhesion in human colon cancer derived HT-29 cells and associates with ezrin.
European journal of cell biology 2006;85(8):769-83.
2006: Natacha Turck; Olivier Lefebvre; Isabelle Gross; Patrick Gendry; Michèle Kedinger; Patricia Simon-Assmann; Jean-François Launay
Effect of laminin-1 on intestinal cell differentiation involves inhibition of nuclear nucleolin.
Journal of cellular physiology 2006;206(2):545-55.
2005: Fabien Alpy; Léa Ritié; Francis Jaubert; François Becmeur; Agnès Méchine-Neuville; Olivier Lefebvre; Christiane Arnold; Lydia Sorokin; Michèle Kedinger; Patricia Simon-Assmann
The expression pattern of laminin isoforms in Hirschsprung disease reveals a distal peripheral nerve differentiation.
Human pathology 2005;36(10):1055-65.
2005: Fabien Alpy; I Jivkov; Lydia Sorokin; Annick Klein; Christiane Arnold; Y Huss; Michèle Kedinger; Patricia Simon-Assmann; Olivier Lefebvre
Generation of a conditionally null allele of the laminin alpha1 gene.
Genesis (New York, N.Y. : 2000) 2005;43(2):59-70.
2005: Natacha Turck; Isabelle Gross; Patrick Gendry; Jeanne Stutzmann; Jean-Noel Freund; Michèle Kedinger; Patricia Simon-Assmann; Jean-François Launay
Laminin isoforms: biological roles and effects on the intracellular distribution of nuclear proteins in intestinal epithelial cells.
Experimental cell research 2005;303(2):494-503.
2004: Owen J Sansom; Karen R Reed; Anthony J Hayes; Heather Ireland; Hannah Brinkmann; Ian P Newton; Eduard Batlle; Patricia Simon-Assmann; Hans Clevers; Inke S Nathke; Alan R Clarke; Douglas J Winton
Loss of Apc in vivo immediately perturbs Wnt signaling, differentiation, and migration.
Genes & development 2004;18(12):1385-90.
2004: Silvia A Piccinni; Anne-Laure Bolcato-Bellemin; Annick Klein; Yang Vincent; Michèle Kedinger; Patricia Simon-Assmann; Olivier Lefebvre
Kruppel-like factors regulate the Lama1 gene encoding the laminin alpha1 chain.
The Journal of biological chemistry 2004;279(10):9103-14.
2004: Natacha Turck; Sophie Richert; Patrick Gendry; Jeanne Stutzmann; Michèle Kedinger; Emmanuelle Leize; Patricia Simon-Assmann; Alain Van Dorsselaer; Jean-François Launay
Proteomic analysis of nuclear proteins from proliferative and differentiated human colonic intestinal epithelial cells.
Proteomics 2004;4(1):93-105.
2004: Thierry Massfelder; Hervé Lang; Eric Schordan; Véronique Lindner; Sylvie Rothhut; Sandra Welsch; Patricia Simon-Assmann; Mariette Barthelmebs; Didier Jacqmin; Jean-Jacques Helwig
Parathyroid hormone-related protein is an essential growth factor for human clear cell renal carcinoma and a target for the von Hippel-Lindau tumor suppressor gene.
Cancer research 2004;64(1):180-8.
2003: Anne-Laure Bolcato-Bellemin; Olivier Lefebvre; Christiane Arnold; Lydia Sorokin; Jeffrey H Miner; Michèle Kedinger; Patricia Simon-Assmann
Laminin alpha5 chain is required for intestinal smooth muscle development.
Developmental biology 2003;260(2):376-90.
2003: Jørgen Olsen; Lene T Kirkeby; Marianne M Brorsson; Sally Dabelsteen; Jesper T Troelsen; Randi Bordoy; Kirsten Fenger; Lars-Inge Larsson; Patricia Simon-Assmann
Converging signals synergistically activate the LAMC2 promoter and lead to accumulation of the laminin gamma 2 chain in human colon carcinoma cells.
The Biochemical journal 2003;371(Pt 1):211-21.
2002: Agnès Méchine-Neuville; Olivier Lefebvre; Jean-Pierre Bellocq; Michèle Kedinger; Patricia Simon-Assmann
[Increased expression of HOXA9 gene in Hirschsprung disease].
Gastroentérologie clinique et biologique 2002;26(12):1110-7.
2001: A De Arcangelis; Olivier Lefebvre; Agnès Méchine-Neuville; Christiane Arnold; Annick Klein; L Rémy; Michèle Kedinger; Patricia Simon-Assmann
Overexpression of laminin alpha1 chain in colonic cancer cells induces an increase in tumor growth.
International journal of cancer. Journal international du cancer 2001;94(1):44-53.
2000: Daniel Aberdam; Thierry Virolle; Patricia Simon-Assmann
Transcriptional regulation of laminin gene expression.
Microscopy research and technique 2000;51(3):228-37.
2000: Jeanne Stutzmann; A Bellissent-Waydelich; L Fontao; Jean-François Launay; Patricia Simon-Assmann
Adhesion complexes implicated in intestinal epithelial cell-matrix interactions.
Microscopy research and technique 2000;51(2):179-90.
2000: J Olsen; Olivier Lefebvre; C Fritsch; Jesper T Troelsen; V Orian-Rousseau; Michèle Kedinger; Patricia Simon-Assmann
Involvement of activator protein 1 complexes in the epithelium-specific activation of the laminin gamma2-chain gene promoter by hepatocyte growth factor (scatter factor).
The Biochemical journal 2000;347(Pt 2):407-17.
2000: Patricia Simon-Assmann; Michèle Kedinger
Tissue recombinants to study extracellular matrix targeting to basement membranes.
Methods in molecular biology (Clifton, N.J.) 2000;139():311-9.
1999: A Bellissent-Waydelich; M T Vanier; C Albigès-Rizo; Patricia Simon-Assmann
Talin concentrates to the midbody region during mammalian cell cytokinesis.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999;47(11):1357-68.
1999: Olivier Lefebvre; Lydia Sorokin; Michèle Kedinger; Patricia Simon-Assmann
Developmental expression and cellular origin of the laminin alpha2, alpha4, and alpha5 chains in the intestine.
Developmental biology 1999;210(1):135-50.
1999: C Fritsch; V Orian-Rousseaul; Olivier Lefebvre; Patricia Simon-Assmann; Jean-Marie Reimund; B Duclos; Michèle Kedinger
Characterization of human intestinal stromal cell lines: response to cytokines and interactions with epithelial cells.
Experimental cell research 1999;248(2):391-406.
1998: Patricia Simon-Assmann; Olivier Lefebvre; A Bellissent-Waydelich; J Olsen; V Orian-Rousseau; A De Arcangelis
The laminins: role in intestinal morphogenesis and differentiation.
Annals of the New York Academy of Sciences 1998;859():46-64.
1998: V Orian-Rousseau; Daniel Aberdam; Patricia Rousselle; Anthea J Messent; Jelena Gavrilovic; Guerrino Meneguzzi; Michèle Kedinger; Patricia Simon-Assmann
Human colonic cancer cells synthesize and adhere to laminin-5. Their adhesion to laminin-5 involves multiple receptors among which is integrin alpha2beta1.
Journal of cell science 1998;111 ( Pt 14)():1993-2004.
1998: Michèle Kedinger; Olivier Lefebvre; Isabelle Duluc; Jean-Noel Freund; Patricia Simon-Assmann
Cellular and molecular partners involved in gut morphogenesis and differentiation.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 1998;353(1370):847-56.
1997: O Lorentz; Isabelle Duluc; A D Arcangelis; Patricia Simon-Assmann; Michèle Kedinger; Jean-Noel Freund
Key role of the Cdx2 homeobox gene in extracellular matrix-mediated intestinal cell differentiation.
The Journal of cell biology 1997;139(6):1553-65.
1997: L Camps; M Kédinger; Patricia Simon-Assmann; D López-Tejero
Effect of prenatal exposure to ethanol on intestinal development of rat fetuses.
Journal of pediatric gastroenterology and nutrition 1997;24(3):302-11.
1997: C Fritsch; Patricia Simon-Assmann; Michèle Kedinger; Gareth Simon Evans
Cytokines modulate fibroblast phenotype and epithelial-stroma interactions in rat intestine.
Gastroenterology 1997;112(3):826-38.
1996: V Orian-Rousseau; Daniel Aberdam; L Fontao; L Chevalier; Guerrino Meneguzzi; Michèle Kedinger; Patricia Simon-Assmann
Developmental expression of laminin-5 and HD1 in the intestine: epithelial to mesenchymal shift for the laminin gamma-2 chain subunit deposition.
Developmental dynamics : an official publication of the American Association of Anatomists 1996;206(1):12-23.
1996: A De Arcangelis; P Neuville; R Boukamel; Olivier Lefebvre; Michèle Kedinger; Patricia Simon-Assmann
Inhibition of laminin alpha 1-chain expression leads to alteration of basement membrane assembly and cell differentiation.
The Journal of cell biology 1996;133(2):417-30.
1995: Patricia Simon-Assmann; Michèle Kedinger; A De Arcangelis; V Rousseau; P Simo
Extracellular matrix components in intestinal development.
Experientia 1995;51(9-10):883-900.
1994: Patricia Simon-Assmann; B Duclos; V Orian-Rousseau; C Arnold; C Mathelin; E Engvall; Michèle Kedinger
Differential expression of laminin isoforms and alpha 6-beta 4 integrin subunits in the developing human and mouse intestine.
Developmental dynamics : an official publication of the American Association of Anatomists 1994;201(1):71-85.
1994: Patricia Simon-Assmann; C Leberquier; N Molto; T Uezato; F Bouziges; Michèle Kedinger
Adhesive properties and integrin expression profiles of two colonic cancer populations differing by their spreading on laminin.
Journal of cell science 1994;107 ( Pt 3)():577-87.
1994: A De Arcangelis; P Simo; T Lesuffleur; Michèle Kedinger; Patricia Simon-Assmann
[Expression of laminin is correlated to the differentiation of human colonic cancer cells].
Gastroentérologie clinique et biologique 1994;18(6-7):630-7.
1992: P Simo; F Bouziges; J C Lissitzky; L Sorokin; Michèle Kedinger; Patricia Simon-Assmann
Dual and asynchronous deposition of laminin chains at the epithelial-mesenchymal interface in the gut.
Gastroenterology 1992;102(6):1835-45.
1992: P Simo; Patricia Simon-Assmann; C Arnold; Michèle Kedinger
Mesenchyme-mediated effect of dexamethasone on laminin in cocultures of embryonic gut epithelial cells and mesenchyme-derived cells.
Journal of cell science 1992;101 ( Pt 1)():161-71.
1991: P Simo; Patricia Simon-Assmann; F Bouziges; C Leberquier; Michèle Kedinger; P Ekblom; L Sorokin
Changes in the expression of laminin during intestinal development.
Development (Cambridge, England) 1991;112(2):477-87.
1991: F Bouziges; P Simo; Patricia Simon-Assmann; K Haffen; Michèle Kedinger
Altered deposition of basement-membrane molecules in co-cultures of colonic cancer cells and fibroblasts.
International journal of cancer. Journal international du cancer 1991;48(1):101-8.
1991: F Bouziges; Patricia Simon-Assmann; P Simo; Michèle Kedinger
Changes in glycosaminoglycan expression in the rat developing intestine.
Cell biology international reports 1991;15(2):97-106.
1990: F Bouziges; Patricia Simon-Assmann; C Leberquier; Jacques Marescaux; J P Bellocq; K Haffen; Michèle Kedinger
Changes in glycosaminoglycan synthesis and in heparan sulfate deposition in human colorectal adenocarcinomas.
International journal of cancer. Journal international du cancer 1990;46(2):189-97.
1990: Michèle Kedinger; Patricia Simon-Assmann; F Bouziges; C Arnold; E Alexandre; K Haffen
Smooth muscle actin expression during rat gut development and induction in fetal skin fibroblastic cells associated with intestinal embryonic epithelium.
Differentiation; research in biological diversity 1990;43(2):87-97.
1990: Patricia Simon-Assmann; F Bouziges; Jean-Noel Freund; F Perrin-Schmitt; Michèle Kedinger
Type IV collagen mRNA accumulates in the mesenchymal compartment at early stages of murine developing intestine.
The Journal of cell biology 1990;110(3):849-57.
1990: Michel Dauça; F Bouziges; S Colin; Michèle Kedinger; M K Keller; J Schilt; Patricia Simon-Assmann; K Haffen
Development of the vertebrate small intestine and mechanisms of cell differentiation.
The International journal of developmental biology 1990;34(1):205-18.
1990: Patricia Simon-Assmann; P Simo; F Bouziges; K Haffen; Michèle Kedinger
Synthesis of basement membrane proteins in the small intestine.
Digestion 1990;46 Suppl 2():12-21.
1989: Patricia Simon-Assmann; F Bouziges; M Vigny; Michèle Kedinger
Origin and deposition of basement membrane heparan sulfate proteoglycan in the developing intestine.
The Journal of cell biology 1989;109(4 Pt 1):1837-48.
1989: B Czernichow; Patricia Simon-Assmann; Michèle Kedinger; C Arnold; M Parache; Jacques Marescaux; Alain Zweibaum; K Haffen
Sucrase-isomaltase expression and enterocytic ultrastructure of human colorectal tumors.
International journal of cancer. Journal international du cancer 1989;44(2):238-44.
1989: F Bouziges; Patricia Simon-Assmann; C Leberquier; K Haffen; Michèle Kedinger
Glycosaminoglycan expression in intestinal epithelial skin-fibroblastic cell cocultures. Fibroblastic cell-mediated effects of glucocorticoids.
Journal of cell science 1989;92 ( Pt 4)():679-85.
1988: Patricia Simon-Assmann; F Bouziges; C Arnold; K Haffen; Michèle Kedinger
Epithelial-mesenchymal interactions in the production of basement membrane components in the gut.
Development (Cambridge, England) 1988;102(2):339-47.
1988: Michèle Kedinger; Patricia Simon-Assmann; F Bouziges; K Haffen
Epithelial-mesenchymal interactions in intestinal epithelial differentiation.
Scandinavian journal of gastroenterology. Supplement 1988;151():62-9.
1987: M Kédinger; Patricia Simon-Assmann; E Alexandre; K Haffen
Importance of a fibroblastic support for in vitro differentiation of intestinal endodermal cells and for their response to glucocorticoids.
Cell differentiation 1987;20(2-3):171-82.
1987: M Kedinger; Patricia Simon-Assmann; K Haffen
Growth and differentiation of intestinal endodermal cells in a coculture system.
Gut 1987;28 Suppl():237-41.
1987: K Haffen; M Kedinger; Patricia Simon-Assmann
Mesenchyme-dependent differentiation of epithelial progenitor cells in the gut.
Journal of pediatric gastroenterology and nutrition 1987;6(1):14-23.
1987: M Kedinger; K Haffen; Patricia Simon-Assmann
Intestinal tissue and cell cultures.
Differentiation; research in biological diversity 1987;36(1):71-85.
1986: Patricia Simon-Assmann; B Lacroix; M Kedinger; K Haffen
Maturation of brush border hydrolases in human fetal intestine maintained in organ culture.
Early human development 1986;13(1):65-74.
1986: M Kedinger; Patricia Simon-Assmann; B Lacroix; A Marxer; Hans-Peter Hauri; K Haffen
Fetal gut mesenchyme induces differentiation of cultured intestinal endodermal and crypt cells.
Developmental biology 1986;113(2):474-83.
1986: Patricia Simon-Assmann; M Kedinger; K Haffen
Immunocytochemical localization of extracellular-matrix proteins in relation to rat intestinal morphogenesis.
Differentiation; research in biological diversity 1986;32(1):59-66.
1986: M Kedinger; Patricia Simon-Assmann; B Lacroix
[Development of the digestive function: regulation of the maturation of intestinal brush border enzymes].
Reproduction, nutrition, development 1986;26(2B):691-702.
1985: B Lacroix; M Kedinger; Patricia Simon-Assmann; K Haffen
Enzymatic response to glucocorticoids of the chick intestinal endoderm associated with various mesenchymal cell types.
Biology of the cell / under the auspices of the European Cell Biology Organization 1985;54(3):235-9.
1984: B Lacroix; M Kedinger; Patricia Simon-Assmann; K Haffen
Early organogenesis of human small intestine: scanning electron microscopy and brush border enzymology.
Gut 1984;25(9):925-30.
1984: B Lacroix; M Kedinger; Patricia Simon-Assmann; Monique Rousset; Alain Zweibaum; K Haffen
Developmental pattern of brush border enzymes in the human fetal colon. Correlation with some morphogenetic events.
Early human development 1984;9(2):95-103.
1984: Patricia Simon-Assmann; M Kédinger; J F Grenier; K Haffen
Organ culture of fetal rat intestine. Effects on brush border enzyme activities of the combined administration of dexamethasone and cycloheximide or actinomycin D.
Enzyme 1984;31(2):65-72.
1984: Patricia Simon-Assmann; M Kedinger; K Haffen
Ability of L-triiodothyronine to modulate glucocorticoid-evoked brush border enzyme activities in cultured fetal rat intestine.
Cell biology international reports 1984;8(1):41-5.
1984: B Lacroix; M Kedinger; Patricia Simon-Assmann; K Haffen
Effects of human fetal gastroenteric mesenchymal cells on some developmental aspects of animal gut endoderm.
Differentiation; research in biological diversity 1984;28(2):129-35.
1983: M Kedinger; Patricia Simon-Assmann; B Lacroix; K Haffen
Role of glucocorticoids on the maturation of brush border enzymes in fetal rat gut endoderm.
Experientia 1983;39(10):1150-2.
1983: K Haffen; B Lacroix; M Kedinger; Patricia Simon-Assmann
Inductive properties of fibroblastic cell cultures derived from rat intestinal mucosa on epithelial differentiation.
Differentiation; research in biological diversity 1983;23(3):226-33.
1982: Patricia Simon-Assmann; M Kedinger; J F Grenier; K Haffen
Control of brush border enzymes by dexamethasone in the fetal rat intestine cultured in vitro.
Journal of pediatric gastroenterology and nutrition 1982;1(2):257-65.
1982: K Haffen; M Kedinger; Patricia Simon-Assmann; B Lacroix
Mesenchyme-dependent differentiation of intestinal brush-border enzymes in the gizzard endoderm of the chick embryo.
Progress in clinical and biological research 1982;85 Pt B():261-70.