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Neal Simon

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Karine M Fabio; Carrie Garippa; Christophe D Guillon; Ned D Heindel; Carl J Lacey; Shi-Fang Lu; Michael J Brownstein; Neal G Simon
Pharmacokinetics and metabolism of SRX246: A potent and selective vasopressin 1a antagonist.
Karine Fabio; Craig F Ferris; Christophe D Guillon; Ned D Heindel; Graham Jones; Carl J Lacey; Shi-Fang Lu; Michael Placzek; Michael J Brownstein; Neal G Simon
Synthesis and evaluation of potent and selective human V1a receptor antagonists as potential ligands for PET or SPECT imaging.
Qianxing Mo; Shifang Lu; Carrie Garippa; Michael J Brownstein; Neal G Simon
Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus.

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All Publications

2013: Karine M Fabio; Carrie Garippa; Christophe D Guillon; Ned D Heindel; Carl J Lacey; Shi-Fang Lu; Michael J Brownstein; Neal G Simon
Pharmacokinetics and metabolism of SRX246: A potent and selective vasopressin 1a antagonist.
Journal of pharmaceutical sciences 2013;102(6):2033-43.
2012: Karine Fabio; Craig F Ferris; Christophe D Guillon; Ned D Heindel; Graham Jones; Carl J Lacey; Shi-Fang Lu; Michael Placzek; Michael J Brownstein; Neal G Simon
Synthesis and evaluation of potent and selective human V1a receptor antagonists as potential ligands for PET or SPECT imaging.
Bioorganic & medicinal chemistry 2012;20(3):1337-45.
2009: Qianxing Mo; Shifang Lu; Carrie Garippa; Michael J Brownstein; Neal G Simon
Genome-wide analysis of DHEA- and DHT-induced gene expression in mouse hypothalamus and hippocampus.
The Journal of steroid biochemistry and molecular biology 2009;114(3-5):135-43.
2008: Neal G Simon; Christophe D Guillon; Karine Fabio; Ned D Heindel; Shi-Fang Lu; Marvin Miller; Craig F Ferris; Michael J Brownstein; Carrie Garripa; Gary A Koppel
Vasopressin antagonists as anxiolytics and antidepressants: recent developments.
Recent patents on CNS drug discovery 2008;3(2):77-93.
2007: Christophe D Guillon; Gary A Koppel; Michael J Brownstein; Michael O Chaney; Craig F Ferris; Shi-Fang Lu; Karine M Fabio; Marvin J Miller; Ned D Heindel; David C Hunden; Robin D G Cooper; Stephen W Kaldor; Jeffrey J Skelton; Bruce A Dressman; Michael P Clay; Mitchell I Steinberg; Robert F Bruns; Neal G Simon
Azetidinones as vasopressin V1a antagonists.
Bioorganic & medicinal chemistry 2007;15(5):2054-80.
2006: Qianxing Mo; Shi-Fang Lu; Neal G Simon
Dehydroepiandrosterone and its metabolites: differential effects on androgen receptor trafficking and transcriptional activity.
The Journal of steroid biochemistry and molecular biology 2006;99(1):50-8.
2006: Craig F Ferris; Shi-Fang Lu; Tara L Messenger; Christophe D Guillon; Ned D Heindel; Marvin Miller; Gary A Koppel; F Robert Bruns; Neal G Simon
Orally active vasopressin V1a receptor antagonist, SRX251, selectively blocks aggressive behavior.
Pharmacology, biochemistry, and behavior 2006;83(2):169-74.
2006: Neal G Simon; Qianxing Mo; Shan Hu; Carrie Garippa; Shi-Fang Lu
Hormonal pathways regulating intermale and interfemale aggression.
International review of neurobiology 2006;73():99-123.
2005: Shan Hu; Shi-Fang Lu; Jay R Kaplan; Michael R Adams; Neal G Simon
ERbeta protein expression in female cynomolgus monkey and CF-1 mouse brain: Western analysis.
Journal of neurobiology 2005;64(3):298-309.
2004: Qianxing Mo; Shi-Fang Lu; Shan Hu; Neal G Simon
DHEA and DHEA sulfate differentially regulate neural androgen receptor and its transcriptional activity.
Brain research. Molecular brain research 2004;126(2):165-72.
2004: Neal G Simon; Jay R Kaplan; Shan Hu; Thomas C Register; Michael R Adams
Increased aggressive behavior and decreased affiliative behavior in adult male monkeys after long-term consumption of diets rich in soy protein and isoflavones.
Hormones and behavior 2004;45(4):278-84.
2003: Shi-Fang Lu; Qianxing Mo; Shan Hu; Carrie Garippa; Neal G Simon
Dehydroepiandrosterone upregulates neural androgen receptor level and transcriptional activity.
Journal of neurobiology 2003;57(2):163-71.
1999: S Lu; Neal G Simon; Y Wang; Shan Hu
Neural androgen receptor regulation: effects of androgen and antiandrogen.
Journal of neurobiology 1999;41(4):505-12.
1999: A Cologer-Clifford; Neal G Simon; M L Richter; S A Smoluk; S Lu
Androgens and estrogens modulate 5-HT1A and 5-HT1B agonist effects on aggression.
Physiology & behavior 1999;65(4-5):823-8.
1998: Shi-Fang Lu; S E McKenna; A Cologer-Clifford; E A Nau; Neal G Simon
Androgen receptor in mouse brain: sex differences and similarities in autoregulation.
Endocrinology 1998;139(4):1594-601.
1998: Neal G Simon; A Cologer-Clifford; Shi-Fang Lu; S E McKenna; Shan Hu
Testosterone and its metabolites modulate 5HT1A and 5HT1B agonist effects on intermale aggression.
Neuroscience and biobehavioral reviews 1998;23(2):325-36.
1997: A Cologer-Clifford; Neal G Simon; Shi-Fang Lu; S A Smoluk
Serotonin agonist-induced decreases in intermale aggression are dependent on brain region and receptor subtype.
Pharmacology, biochemistry, and behavior 1997;58(2):425-30.
1996: A Cologer-Clifford; S A Smoluk; Neal G Simon
Effects of serotonergic1A and 1B agonists in androgenic versus estrogenic systems for aggression.
Annals of the New York Academy of Sciences 1996;794():339-42.
1996: Neal G Simon; S E McKenna; Shi-Fang Lu; A Cologer-Clifford
Development and expression of hormonal systems regulating aggression.
Annals of the New York Academy of Sciences 1996;794():8-17.
1993: S E McKenna; Neal G Simon
Genetic differences in progestin sensitivity in CD-1 and SW female mice.
Physiology & behavior 1993;54(1):167-70.
1992: S E McKenna; Neal G Simon; A Cologer-Clifford
An assessment of agonist/antagonist effects of tamoxifen in the female mouse brain.
Hormones and behavior 1992;26(4):536-44.
1992: A Cologer-Clifford; Neal G Simon; B M Jubilan
Genotype, uterine position, and testosterone sensitivity in older female mice.
Physiology & behavior 1992;51(5):1047-50.
1991: Neal G Simon; A Cologer-Clifford
In utero contiguity to males does not influence morphology, behavioral sensitivity to testosterone, or hypothalamic androgen binding in CF-1 female mice.
Hormones and behavior 1991;25(4):518-30.
1991: W P Klein; Neal G Simon
Timing of neonatal testosterone exposure in the differentiation of estrogenic regulatory systems for aggression.
Physiology & behavior 1991;50(1):91-3.
1990: X A Chen; Neal G Simon
Genetic variation in hypothalamic methyltrienolone (R1881) binding in male mice.
Physiology & behavior 1990;47(3):589-92.
1988: Neal G Simon; M Perry
Medroxyprogesterone acetate and tamoxifen do not decrease aggressive behavior in CF-1 male mice.
Pharmacology, biochemistry, and behavior 1988;30(4):829-33.
1987: Neal G Simon; R E Whalen
Sexual differentiation of androgen-sensitive and estrogen-sensitive regulatory systems for aggressive behavior.
Hormones and behavior 1987;21(4):493-500.
1987: Neal G Simon; David Masters
Activation of male-typical aggression by testosterone but not its metabolites in C57BL/6J female mice.
Physiology & behavior 1987;41(5):405-7.
1985: Neal G Simon; R E Whalen; M P Tate
Induction of male-typical aggression by androgens but not by estrogens in adult female mice.
Hormones and behavior 1985;19(2):204-12.
1984: R E Whalen; Neal G Simon
Biological motivation.
Annual review of psychology 1984;35():257-76.