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Jan Simoni

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Nimrit Goraya; Chan-Hee Jo; Jan Simoni; Donald E Wesson
A comparison of treating metabolic acidosis in CKD stage 4 hypertensive kidney disease with fruits and vegetables or sodium bicarbonate.
Jan Simoni; Donald E Wesson; Grace Simoni; Mario Feola
ATP-adenosine-glutathione cross-linked hemoglobin as clinically useful oxygen carrier.
Jan Simoni; Mario Feola; John A Griswold; John F Moeller; Grace Simoni; Donald E Wesson
Adenosine-5'-triphosphate-adenosine-glutathione cross-linked hemoglobin as erythropoiesis-stimulating agent.

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All Publications

2013: Nimrit Goraya; Chan-Hee Jo; Jan Simoni; Donald E Wesson
A comparison of treating metabolic acidosis in CKD stage 4 hypertensive kidney disease with fruits and vegetables or sodium bicarbonate.
Clinical journal of the American Society of Nephrology : CJASN 2013;8(3):371-81.
2012: Jan Simoni; Donald E Wesson; Grace Simoni; Mario Feola
ATP-adenosine-glutathione cross-linked hemoglobin as clinically useful oxygen carrier.
Current drug discovery technologies 2012;9(3):173-87.
2012: Jan Simoni; Mario Feola; John A Griswold; John F Moeller; Grace Simoni; Donald E Wesson
Adenosine-5'-triphosphate-adenosine-glutathione cross-linked hemoglobin as erythropoiesis-stimulating agent.
Artificial organs 2012;36(2):139-50.
2012: Jan Simoni
Artificial oxygen carriers: renewed commercial interest and scientific/technological advances.
Artificial organs 2012;36(2):123-6.
2010: Mohammad Otahbachi; Jan Simoni; Grace Simoni; John F Moeller; Cihan Cevik; Gary E Meyerrose; Chanwit Roongsritong
Gender differences in platelet aggregation in healthy individuals.
Journal of thrombosis and thrombolysis 2010;30(2):184-91.
2010: Sorot Phisitkul; Apurv Khanna; Jan Simoni; Kristine Broglio; Simon Sheather; Mohammad Hasan Rajab; Donald E Wesson
Amelioration of metabolic acidosis in patients with low GFR reduced kidney endothelin production and kidney injury, and better preserved GFR.
Kidney international 2010;77(7):617-23.
2010: Warangkana Chokesuwattanaskul; Yasir Yaqub; Jose A Suarez; Jan Simoni; Grace Simoni; Kenneth M Nugent; Rosalinda Jimenez; Alejandro Perez-Verdia
Effect of pioglitazone on platelet aggregation in a healthy cohort.
Cardiology 2010;116(4):253-6.
2009: Jan Simoni; Javier Villanueva-Meyer; Grace Simoni; John F Moeller; Donald E Wesson
Control of oxidative reactions of hemoglobin in the design of blood substitutes: role of the ascorbate-glutathione antioxidant system.
Artificial organs 2009;33(2):115-26.
2009: Jan Simoni; Grace Simoni; John F Moeller
Intrinsic toxicity of hemoglobin: how to counteract it.
Artificial organs 2009;33(2):100-9.
2008: Kantima Phisitkul; Khaled Hegazy; Temduang Chuahirun; Cathy Hudson; Jan Simoni; Hasan Rajab; Donald E Wesson
Continued smoking exacerbates but cessation ameliorates progression of early type 2 diabetic nephropathy.
The American journal of the medical sciences 2008;335(4):284-91.
2008: S Phisitkul; Callenda Hacker; Jan Simoni; Ruc Tran; Donald E Wesson
Dietary protein causes a decline in the glomerular filtration rate of the remnant kidney mediated by metabolic acidosis and endothelin receptors.
Kidney international 2008;73(2):192-9.
2007: Donald E Wesson; T Nathan; T Rose; Jan Simoni; Ruc Tran
Dietary protein induces endothelin-mediated kidney injury through enhanced intrinsic acid production.
Kidney international 2007;71(3):210-7.
2007: Jan Simoni; Grace Simoni; John F Moeller; James P Tsikouris; Donald E Wesson
Evaluation of angiotensin converting enzyme (ACE)-like activity of acellular hemoglobin.
Artificial cells, blood substitutes, and immobilization biotechnology 2007;35(2):191-210.
2006: Jan Simoni; Grace Simoni; John A Griswold; John F Moeller; James P Tsikouris; Apurv Khanna; Chanwit Roongsritong; Donald E Wesson
Role of free hemoglobin in 8-iso prostaglandin F2-alpha synthesis in chronic renal failure and its impact on CD163-Hb scavenger receptor and on coronary artery endothelium.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2006;52(6):652-61.
2006: James P Tsikouris; Craig D Cox; Jan Simoni; Charles F Seifert; Miranda C Peek; Gary E Meyerrose
Lack of effect on coronary atherosclerotic disease biomarkers with modest dosing of an angiotensin-converting enzyme inhibitor, angiotensin II type-1 receptor blocker, and the combination.
Coronary artery disease 2006;17(5):439-45.
2006: Chanwit Roongsritong; Jason Bradley; Piraon Sutthiwan; Jan Simoni; Ahmed Arif; Gary E Meyerrose
Elevated carboxy-terminal peptide of procollagen type I in elderly patients with diastolic dysfunction.
The American journal of the medical sciences 2006;331(3):131-3.
2006: Donald E Wesson; Jan Simoni; Sharma Prabhakar
Endothelin-induced increased nitric oxide mediates augmented distal nephron acidification as a result of dietary protein.
Journal of the American Society of Nephrology : JASN 2006;17(2):406-13.
2005: Chanwit Roongsritong; Piraon Sutthiwan; Jason Bradley; Jan Simoni; Sherrie Power; Gary E Meyerrose
Spironolactone improves diastolic function in the elderly.
Clinical cardiology 2005;28(10):484-7.
2005: Larry Warmoth; Monette M Regalado; Jan Simoni; Ronald B Harrist; Donald E Wesson
Cigarette smoking enhances increased urine albumin excretion as a risk factor for glomerular filtration rate decline in primary hypertension.
The American journal of the medical sciences 2005;330(3):111-9.
2005: Apurv Khanna; Jan Simoni; Donald E Wesson
Endothelin-induced increased aldosterone activity mediates augmented distal nephron acidification as a result of dietary protein.
Journal of the American Society of Nephrology : JASN 2005;16(7):1929-35.
2005: Apurv Khanna; Jan Simoni; Callenda Hacker; Marie-Josee Duran; Donald E Wesson
Increased endothelin activity mediates augmented distal nephron acidification induced by dietary protein.
Transactions of the American Clinical and Climatological Association 2005;116():239-56; discussion 257-8.
2004: James P Tsikouris; Jan Simoni; Jose A Suarez; Piraon Sutthiwan; Martin Ziska; Gary E Meyerrose
Comparison of effects of quinapril versus enalapril on vasoactive substances following acute myocardial infarction.
The American journal of cardiology 2004;94(5):641-3, A9.
2004: Apurv Khanna; Jan Simoni; Callenda Hacker; Marie-Josee Duran; Donald E Wesson
Increased endothelin activity mediates augmented distal nephron acidification induced by dietary protein.
Journal of the American Society of Nephrology : JASN 2004;15(9):2266-75.
2004: James P Tsikouris; Jose A Suarez; Jan Simoni; Martin Ziska; Gary E Meyerrose
Exploring the effects of ACE inhibitor tissue penetration on vascular inflammation following acute myocardial infarction.
Coronary artery disease 2004;15(4):211-7.
2004: Temduang Chuahirun; Jan Simoni; Cathy Hudson; Timothy Seipel; Apurv Khanna; Ronald B Harrist; Donald E Wesson
Cigarette smoking exacerbates and its cessation ameliorates renal injury in type 2 diabetes.
The American journal of the medical sciences 2004;327(2):57-67.
2004: J Ashley Jefferson; Jan Simoni; Elizabeth Escudero; Maria-Elena Hurtado; Erik R Swenson; Donald E Wesson; George F Schreiner; Robert B Schoene; Richard J Johnson; Abdias Hurtado
Increased oxidative stress following acute and chronic high altitude exposure.
High altitude medicine & biology 2004;5(1):61-9.
2000: Jan Simoni; Grace Simoni; Donald E Wesson; John A Griswold; M Feola
A novel hemoglobin-adenosine-glutathione based blood substitute: evaluation of its effects on human blood ex vivo.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2000;46(6):679-92.
2000: M Feola; Jan Simoni
"Is there a need for blood substitutes in the new millennium and what should we expect in the way of safety and efficacy?".
Artificial cells, blood substitutes, and immobilization biotechnology 2000;28(2):vii-ix.
1998: Jan Simoni; Grace Simoni; Raul Martinez-Zaguilan; Donald E Wesson; CD Lox; SD Prien; R V Kumar
Improved blood substitute: evaluation of its effects on human endothelial cells.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1998;44(5):M356-67.
1998: Donald E Wesson; Jan Simoni; Dollie Green
Reduced extracellular pH increases endothelin-1 secretion by human renal microvascular endothelial cells.
The Journal of clinical investigation 1998;101(3):578-83.
1997: Jan Simoni; Grace Simoni; A Hartsell; M Feola
An improved blood substitute. In vivo evaluation of its renal effects.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1997;43(5):M714-25.
1997: Jan Simoni; Grace Simoni; CD Lox; SD Prien; Ruc Tran; G Tom Shires
Expression of adhesion molecules and von Willebrand factor in human coronary artery endothelial cells incubated with differently modified hemoglobin solutions.
Artificial cells, blood substitutes, and immobilization biotechnology 1997;25(1-2):211-25.
1997: Jan Simoni; Grace Simoni; CD Lox; SD Prien; G Tom Shires
Modified hemoglobin solution, with desired pharmacological properties, does not activate nuclear transcription factor NF-kappa B in human vascular endothelial cells.
Artificial cells, blood substitutes, and immobilization biotechnology 1997;25(1-2):193-210.
1996: Jan Simoni; Grace Simoni; G Newman; M Feola
An improved blood substitute. In vivo evaluation of its hemodynamic effects.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1996;42(5):M773-82.
1995: Jan Simoni; Grace Simoni; Charles Lox; S D Prien; G Tom Shires
Evidence for the direct inhibition of endothelin-1 secretion by hemoglobin in human endothelial cells.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 1995;41(3):M641-51.
1995: Jan Simoni; Grace Simoni; E L Garcia; S D Prien; R M Tran; M Feola; G Tom Shires
Protective effect of selenium on hemoglobin mediated lipid peroxidation in vivo.
Artificial cells, blood substitutes, and immobilization biotechnology 1995;23(4):469-86.
1994: Jan Simoni; Grace Simoni; Charles Lox; M Feola
Reaction of human endothelial cells to bovine hemoglobin solutions and tumor necrosis factor.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):777-87.
1994: Jan Simoni; Grace Simoni; Charles Lox; D E McGunegle; M Feola
Cytokines and PAF release from human monocytes and macrophages: effect of hemoglobin and contaminants.
Artificial cells, blood substitutes, and immobilization biotechnology 1994;22(3):525-34.
1992: M Hirthler; Jan Simoni; M Dickson
Elevated levels of endotoxin, oxygen-derived free radicals, and cytokines during extracorporeal membrane oxygenation.
Journal of pediatric surgery 1992;27(9):1199-202.
1992: M Feola; Jan Simoni; R Angelillo; Z Luhruma; M Kabakele; M Manzombi; M Kaluila
Clinical trial of a hemoglobin based blood substitute in patients with sickle cell anemia.
Surgery, gynecology & obstetrics 1992;174(5):379-86.
1991: M Feola; Jan Simoni; P C Canizaro
Quality control of hemoglobin solutions. I. The purity of hemoglobin before modification.
Artificial organs 1991;15(3):243-8.
1990: M E Dickson; M A Hirthler; Jan Simoni; C A Bradley; J F Goldthorn
Stunned myocardium during extracorporeal membrane oxygenation.
American journal of surgery 1990;160(6):644-6.
1990: Jan Simoni; M Feola; R Tran; M Buckner; P C Canizaro
Biocompatibility of hemoglobin solutions. II. The inflammatory reaction of human monocytes and mouse peritoneal macrophages.
Artificial organs 1990;14(2):98-109.
1990: Jan Simoni; M Feola; P C Canizaro
Generation of free oxygen radicals and the toxicity of hemoglobin solutions.
Biomaterials, artificial cells, and artificial organs 1990;18(2):189-202.
1990: M Feola; Jan Simoni; R Tran; P C Canizaro
Nephrotoxicity of hemoglobin solutions.
Biomaterials, artificial cells, and artificial organs 1990;18(2):233-49.
1989: M Feola; Jan Simoni; R Tran; Charles Lox; P C Canizaro
Toxic factors in the red blood cell membrane.
The Journal of trauma 1989;29(8):1065-75.
1989: M Feola; Jan Simoni; D Fishman; R Tran; P C Canizaro
Biocompatibility of hemoglobin solutions. I. Reactions of vascular endothelial cells to pure and impure hemoglobins.
Artificial organs 1989;13(3):209-15.
1989: M K Dobke; Jan Simoni; J L Ninnemann; J Garrett; T J Harnar
Endotoxemia after burn injury: effect of early excision on circulating endotoxin levels.
The Journal of burn care & rehabilitation 1989;10(2):107-11.
1989: M Feola; Jan Simoni; R Tran; Charles Lox; P C Canizaro
The toxicity of erythrocytic stroma.
Progress in clinical and biological research 1989;319():361-80; discussion 381-2.
1988: M Feola; Jan Simoni; M Dobke; P C Canizaro
Complement activation and the toxicity of stroma-free hemoglobin solutions in primates.
Circulatory shock 1988;25(4):275-90.
1988: M Feola; Jan Simoni; P C Canizaro; R Tran; G Raschbaum; F J Behal
Toxicity of polymerized hemoglobin solutions.
Surgery, gynecology & obstetrics 1988;166(3):211-22.
1988: M Feola; Jan Simoni; R Tran; P C Canizaro
Mechanisms of toxicity of hemoglobin solutions.
Biomaterials, artificial cells, and artificial organs 1988;16(1-3):217-26.
1987: T J Harnar; M Dobke; Jan Simoni; J L Ninnemann
Toxic epidermal necrolysis complicated by severe wound sepsis: a case study.
The Journal of burn care & rehabilitation 1987;8(6):554-7.