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Kai Simons
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28
Parton, Robert
15
Shevchenko, Andrej
14
Dotti, Carlos
13
Zerial, Marino
11
Dupree, Paul
9
Lafont, F
8
Olkkonen, Vesa
8
Schuck, Sebastian
8
Verkade, P
8
Kurzchalia, Teymuras
7
Scheiffele, P
7
Pimplikar, Sanjay
7
Verkade, Paul
7
Keller, Philipp
7
Bagnat, Michel
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All Publications
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2009: Lingwood Daniel; Kaiser Hermann-Josef; Levental Ilya; Simons Kai
Lipid rafts as functional heterogeneity in cell membranes.
Biochemical Society transactions 2009;37(Pt 5):955-60.
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2009: Lingwood Daniel; Schuck Sebastian; Ferguson Charles; Gerl Mathias; Simons Kai
Morphological homeostasis by autophagy.
Autophagy 2009;5(7):1039-40.
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2009: Kaiser Hermann-Josef; Lingwood Daniel; Levental Ilya; Sampaio Julio L; Kalvodova Lucie; Rajendran Lawrence; Simons Kai
Order of lipid phases in model and plasma membranes.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(39):16645-50.
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2009: Kalvodova Lucie; Sampaio Julio L; Cordo Sandra; Ejsing Christer S; Shevchenko Andrej; Simons Kai
The lipidomes of vesicular stomatitis virus, semliki forest virus, and the host plasma membrane analyzed by quantitative shotgun mass spectrometry.
Journal of virology 2009;83(16):7996-8003.
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2009: Klemm Robin W; Ejsing Christer S; Surma Michal A; Kaiser Hermann-Josef; Gerl Mathias J; Sampaio Julio L; de Robillard Quentin; Ferguson Charles; Proszynski Tomasz J; Shevchenko Andrej; Simons Kai
Segregation of sphingolipids and sterols during formation of secretory vesicles at the trans-Golgi network.
The Journal of cell biology 2009;185(4):601-12.
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2009: Lingwood Daniel; Schuck Sebastian; Ferguson Charles; Gerl Mathias J; Simons Kai
Generation of cubic membranes by controlled homotypic interaction of membrane proteins in the endoplasmic reticulum.
The Journal of biological chemistry 2009;284(18):12041-8.
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2009: Zech Tobias; Ejsing Christer S; Gaus Katharina; de Wet Ben; Shevchenko Andrej; Simons Kai; Harder Thomas
Accumulation of raft lipids in T-cell plasma membrane domains engaged in TCR signalling.
The EMBO journal 2009;28(5):466-76.
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2009: Ejsing Christer S; Sampaio Julio L; Surendranath Vineeth; Duchoslav Eva; Ekroos Kim; Klemm Robin W; Simons Kai; Shevchenko Andrej
Global analysis of the yeast lipidome by quantitative shotgun mass spectrometry.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(7):2136-41.
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2008: Lingwood Daniel; Ries Jonas; Schwille Petra; Simons Kai
Plasma membranes are poised for activation of raft phase coalescence at physiological temperature.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(29):10005-10.
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2008: Rajendran Lawrence; Schneider Anja; Schlechtingen Georg; Weidlich Sebastian; Ries Jonas; Braxmeier Tobias; Schwille Petra; Schulz Jörg B; Schroeder Cornelia; Simons Mikael; Jennings Gary; Knölker Hans-Joachim; Simons Kai
Efficient inhibition of the Alzheimer's disease beta-secretase by membrane targeting.
Science (New York, N.Y.) 2008;320(5875):520-3.
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2008: Torkko Juha M; Manninen Aki; Schuck Sebastian; Simons Kai
Depletion of apical transport proteins perturbs epithelial cyst formation and ciliogenesis.
Journal of cell science 2008;121(Pt 8):1193-203.
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2008: Heimerl Susanne; Liebisch Gerhard; Le Lay Soazig; Böttcher Alfred; Wiesner Philipp; Lindtner Silke; Kurzchalia Teymuras V; Simons Kai; Schmitz Gerd
Caveolin-1 deficiency alters plasma lipid and lipoprotein profiles in mice.
Biochemical and biophysical research communications 2008;367(4):826-33.
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2007: Friedrichs Jens; Torkko Juha M; Helenius Jonne; Teräväinen Terhi P; Füllekrug Joachim; Muller Daniel J; Simons Kai; Manninen Aki
Contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy.
The Journal of biological chemistry 2007;282(40):29375-83.
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2007: Schuck Sebastian; Gerl Mathias J; Ang Agnes; Manninen Aki; Keller Patrick; Mellman Ira; Simons Kai
Rab10 is involved in basolateral transport in polarized Madin-Darby canine kidney cells.
Traffic (Copenhagen, Denmark) 2007;8(1):47-60.
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2007: Lingwood Daniel; Simons Kai
Detergent resistance as a tool in membrane research.
Nature protocols 2007;2(9):2159-65.
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2007: Rajendran Lawrence; Knobloch Marlen; Geiger Kathrin D; Dienel Stephanie; Nitsch Roger; Simons Kai; Konietzko Uwe
Increased Abeta production leads to intracellular accumulation of Abeta in flotillin-1-positive endosomes.
Neuro-degenerative diseases 2007;4(2-3):164-70.
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2006: Vieira Otilia V; Gaus Katharina; Verkade Paul; Fullekrug Joachim; Vaz Winchil L C; Simons Kai
FAPP2, cilium formation, and compartmentalization of the apical membrane in polarized Madin-Darby canine kidney (MDCK) cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(49):18556-61.
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2006: Ejsing Christer S; Duchoslav Eva; Sampaio Julio; Simons Kai; Bonner Ron; Thiele Christoph; Ekroos Kim; Shevchenko Andrej
Automated identification and quantification of glycerophospholipid molecular species by multiple precursor ion scanning.
Analytical chemistry 2006;78(17):6202-14.
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2006: Rajendran Lawrence; Honsho Masanori; Zahn Tobias R; Keller Patrick; Geiger Kathrin D; Verkade Paul; Simons Kai
Alzheimer's disease beta-amyloid peptides are released in association with exosomes.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(30):11172-7.
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2006: Proszynski Tomasz J; Klemm Robin; Bagnat Michel; Gaus Katharina; Simons Kai
Plasma membrane polarization during mating in yeast cells.
The Journal of cell biology 2006;173(6):861-6.
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2006: Le Lay Soazig; Hajduch Eric; Lindsay Margaret R; Le Lièpvre Xavier; Thiele Christoph; Ferré Pascal; Parton Robert G; Kurzchalia Teymuras; Simons Kai; Dugail Isabelle
Cholesterol-induced caveolin targeting to lipid droplets in adipocytes: a role for caveolar endocytosis.
Traffic (Copenhagen, Denmark) 2006;7(5):549-61.
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2006: Schuck Sebastian; Simons Kai
Controversy fuels trafficking of GPI-anchored proteins.
The Journal of cell biology 2006;172(7):963-5.
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2006: Ejsing Christer S; Moehring Thomas; Bahr Ute; Duchoslav Eva; Karas Michael; Simons Kai; Shevchenko Andrej
Collision-induced dissociation pathways of yeast sphingolipids and their molecular profiling in total lipid extracts: a study by quadrupole TOF and linear ion trap-orbitrap mass spectrometry.
Journal of mass spectrometry : JMS 2006;41(3):372-89.
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2006: Meder Doris; Moreno Maria Joao; Verkade Paul; Vaz Winchil L C; Simons Kai
Phase coexistence and connectivity in the apical membrane of polarized epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(2):329-34.
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2006: Füllekrug Joachim; Shevchenko Anna; Shevchenko Andrej; Simons Kai
Identification of glycosylated marker proteins of epithelial polarity in MDCK cells by homology driven proteomics.
BMC biochemistry 2006;7():8.
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2005: Proszynski Tomasz J; Klemm Robin W; Gravert Maike; Hsu Peggy P; Gloor Yvonne; Wagner Jan; Kozak Karol; Grabner Hannes; Walzer Karen; Bagnat Michel; Simons Kai; Walch-Solimena Christiane
A genome-wide visual screen reveals a role for sphingolipids and ergosterol in cell surface delivery in yeast.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(50):17981-6.
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2005: Manninen Aki; Verkade Paul; Le Lay Soazig; Torkko Juha; Kasper Michael; Füllekrug Joachim; Simons Kai
Caveolin-1 is not essential for biosynthetic apical membrane transport.
Molecular and cellular biology 2005;25(22):10087-96.
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2005: Kalvodova Lucie; Kahya Nicoletta; Schwille Petra; Ehehalt Robert; Verkade Paul; Drechsel David; Simons Kai
Lipids as modulators of proteolytic activity of BACE: involvement of cholesterol, glycosphingolipids, and anionic phospholipids in vitro.
The Journal of biological chemistry 2005;280(44):36815-23.
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2005: Vieira Otilia V; Verkade Paul; Manninen Aki; Simons Kai
FAPP2 is involved in the transport of apical cargo in polarized MDCK cells.
The Journal of cell biology 2005;170(4):521-6.
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2005: Meder Doris; Simons Kai
Cell biology. Ras on the roundabout.
Science (New York, N.Y.) 2005;307(5716):1731-3.
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2005: Rajendran Lawrence; Simons Kai
Lipid rafts and membrane dynamics.
Journal of cell science 2005;118(Pt 6):1099-102.
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2005: Meder Doris; Shevchenko Anna; Simons Kai; Füllekrug Joachim
Gp135/podocalyxin and NHERF-2 participate in the formation of a preapical domain during polarization of MDCK cells.
The Journal of cell biology 2005;168(2):303-13.
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2004: Schuck Sebastian; Simons Kai
Polarized sorting in epithelial cells: raft clustering and the biogenesis of the apical membrane.
Journal of cell science 2004;117(Pt 25):5955-64.
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2004: Poole Kate; Meder Doris; Simons Kai; Müller Daniel
The effect of raft lipid depletion on microvilli formation in MDCK cells, visualized by atomic force microscopy.
FEBS letters 2004;565(1-3):53-8.
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2004: Füllekrug Joachim; Simons Kai
Lipid rafts and apical membrane traffic.
Annals of the New York Academy of Sciences 2004;1014():164-9.
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2004: Schuck Sebastian; Manninen Aki; Honsho Masanori; Füllekrug Joachim; Simons Kai
Generation of single and double knockdowns in polarized epithelial cells by retrovirus-mediated RNA interference.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):4912-7.
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2004: Proszynski Tomasz J; Simons Kai; Bagnat Michel
O-glycosylation as a sorting determinant for cell surface delivery in yeast.
Molecular biology of the cell 2004;15(4):1533-43.
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2004: Simons Kai; Vaz Winchil L C
Model systems, lipid rafts, and cell membranes.
Annual review of biophysics and biomolecular structure 2004;33():269-95.
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2003: Ekroos Kim; Ejsing Christer S; Bahr Ute; Karas Michael; Simons Kai; Shevchenko Andrej
Charting molecular composition of phosphatidylcholines by fatty acid scanning and ion trap MS3 fragmentation.
Journal of lipid research 2003;44(11):2181-92.
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2003: Schuck Sebastian; Honsho Masanori; Ekroos Kim; Shevchenko Andrej; Simons Kai
Resistance of cell membranes to different detergents.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):5795-800.
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2003: Lahtinen Ulla; Honsho Masanori; Parton Robert G; Simons Kai; Verkade Paul
Involvement of caveolin-2 in caveolar biogenesis in MDCK cells.
FEBS letters 2003;538(1-3):85-8.
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2003: Ehehalt Robert; Keller Patrick; Haass Christian; Thiele Christoph; Simons Kai
Amyloidogenic processing of the Alzheimer beta-amyloid precursor protein depends on lipid rafts.
The Journal of cell biology 2003;160(1):113-23.
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2002: Bagnat Michel; Simons Kai
Lipid rafts in protein sorting and cell polarity in budding yeast Saccharomyces cerevisiae.
Biological chemistry 2002;383(10):1475-80.
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2002: Bagnat Michel; Simons Kai
Cell surface polarization during yeast mating.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(22):14183-8.
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2002: Simons Kai; Ehehalt Robert
Cholesterol, lipid rafts, and disease.
The Journal of clinical investigation 2002;110(5):597-603.
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2002: Ehehalt Robert; Michel Beate; De Pietri Tonelli Davide; Zacchetti Daniele; Simons Kai; Keller Patrick
Splice variants of the beta-site APP-cleaving enzyme BACE1 in human brain and pancreas.
Biochemical and biophysical research communications 2002;293(1):30-7.
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2002: Ekroos Kim; Chernushevich Igor V; Simons Kai; Shevchenko Andrej
Quantitative profiling of phospholipids by multiple precursor ion scanning on a hybrid quadrupole time-of-flight mass spectrometer.
Analytical chemistry 2002;74(5):941-9.
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2001: Bagnat M; Chang A; Simons K
Plasma membrane proton ATPase Pma1p requires raft association for surface delivery in yeast.
Molecular biology of the cell 2001;12(12):4129-38.
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2001: Simons K
Lessons in science politics.
Nature reviews. Molecular cell biology 2001;2(12):931-3.
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2001: Lafont F; Simons K
Raft-partitioning of the ubiquitin ligases Cbl and Nedd4 upon IgE-triggered cell signaling.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(6):3180-4.
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2001: Keller P; Toomre D; Díaz E; White J; Simons K
Multicolour imaging of post-Golgi sorting and trafficking in live cells.
Nature cell biology 2001;3(2):140-9.
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2000: Simons K; Ikonen E
How cells handle cholesterol.
Science (New York, N.Y.) 2000;290(5497):1721-6.
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2000: Simons K; Gruenberg J
Jamming the endosomal system: lipid rafts and lysosomal storage diseases.
Trends in cell biology 2000;10(11):459-62.
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2000: Simons K; Toomre D
Lipid rafts and signal transduction.
Nature reviews. Molecular cell biology 2000;1(1):31-9.
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2000: Lecat S; Verkade P; Thiele C; Fiedler K; Simons K; Lafont F
Different properties of two isoforms of annexin XIII in MDCK cells.
Journal of cell science 2000;113 ( Pt 14)():2607-18.
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2000: Plant P J; Lafont F; Lecat S; Verkade P; Simons K; Rotin D
Apical membrane targeting of Nedd4 is mediated by an association of its C2 domain with annexin XIIIb.
The Journal of cell biology 2000;149(7):1473-84.
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2000: Toomre D; Steyer J A; Keller P; Almers W; Simons K
Fusion of constitutive membrane traffic with the cell surface observed by evanescent wave microscopy.
The Journal of cell biology 2000;149(1):33-40.
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2000: Bagnat M; Keränen S; Shevchenko A; Shevchenko A; Simons K
Lipid rafts function in biosynthetic delivery of proteins to the cell surface in yeast.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3254-9.
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2000: Pralle A; Keller P; Florin E L; Simons K; Hörber J K
Sphingolipid-cholesterol rafts diffuse as small entities in the plasma membrane of mammalian cells.
The Journal of cell biology 2000;148(5):997-1008.
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2000: Verkade P; Harder T; Lafont F; Simons K
Induction of caveolae in the apical plasma membrane of Madin-Darby canine kidney cells.
The Journal of cell biology 2000;148(4):727-39.
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2000: Benting J; Lecat S; Zacchetti D; Simons K
Protein expression in Drosophila Schneider cells.
Analytical biochemistry 2000;278(1):59-68.
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1999: Benting J; Rietveld A; Ansorge I; Simons K
Acyl and alkyl chain length of GPI-anchors is critical for raft association in vitro.
FEBS letters 1999;462(1-2):47-50.
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1999: Füllekrug J; Scheiffele P; Simons K
VIP36 localisation to the early secretory pathway.
Journal of cell science 1999;112 ( Pt 17)():2813-21.
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1999: Benting J H; Rietveld A G; Simons K
N-Glycans mediate the apical sorting of a GPI-anchored, raft-associated protein in Madin-Darby canine kidney cells.
The Journal of cell biology 1999;146(2):313-20.
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1999: Cheong K H; Zacchetti D; Schneeberger E E; Simons K
VIP17/MAL, a lipid raft-associated protein, is involved in apical transport in MDCK cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(11):6241-8.
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1999: Rietveld A; Neutz S; Simons K; Eaton S
Association of sterol- and glycosylphosphatidylinositol-linked proteins with Drosophila raft lipid microdomains.
The Journal of biological chemistry 1999;274(17):12049-54.
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1999: Lafont F; Verkade P; Galli T; Wimmer C; Louvard D; Simons K
Raft association of SNAP receptors acting in apical trafficking in Madin-Darby canine kidney cells.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(7):3734-8.
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1999: Harder T; Simons K
Clusters of glycolipid and glycosylphosphatidylinositol-anchored proteins in lymphoid cells: accumulation of actin regulated by local tyrosine phosphorylation.
European journal of immunology 1999;29(2):556-62.
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1999: Scheiffele P; Rietveld A; Wilk T; Simons K
Influenza viruses select ordered lipid domains during budding from the plasma membrane.
The Journal of biological chemistry 1999;274(4):2038-44.
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1999: Toomre D; Keller P; White J; Olivo J C; Simons K
Dual-color visualization of trans-Golgi network to plasma membrane traffic along microtubules in living cells.
Journal of cell science 1999;112 ( Pt 1)():21-33.
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1998: Rietveld A; Simons K
The differential miscibility of lipids as the basis for the formation of functional membrane rafts.
Biochimica et biophysica acta 1998;1376(3):467-79.
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1998: Lafont F; Lecat S; Verkade P; Simons K
Annexin XIIIb associates with lipid microdomains to function in apical delivery.
The Journal of cell biology 1998;142(6):1413-27.
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1998: Simons M; Keller P; De Strooper B; Beyreuther K; Dotti C G; Simons K
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(11):6460-4.
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1998: Harder T; Scheiffele P; Verkade P; Simons K
Lipid domain structure of the plasma membrane revealed by patching of membrane components.
The Journal of cell biology 1998;141(4):929-42.
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1998: Ledesma M D; Simons K; Dotti C G
Neuronal polarity: essential role of protein-lipid complexes in axonal sorting.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(7):3966-71.
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1998: Keller P; Simons K
Cholesterol is required for surface transport of influenza virus hemagglutinin.
The Journal of cell biology 1998;140(6):1357-67.
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1998: Scheiffele P; Verkade P; Fra A M; Virta H; Simons K; Ikonen E
Caveolin-1 and -2 in the exocytic pathway of MDCK cells.
The Journal of cell biology 1998;140(4):795-806.
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1997: Shevchenko A; Keller P; Scheiffele P; Mann M; Simons K
Identification of components of trans-Golgi network-derived transport vesicles and detergent-insoluble complexes by nanoelectrospray tandem mass spectrometry.
Electrophoresis 1997;18(14):2591-600.
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1997: Keller P; Simons K
Post-Golgi biosynthetic trafficking.
Journal of cell science 1997;110 ( Pt 24)():3001-9.
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1997: Ikonen E; de Almeid J B; Fath K R; Burgess D R; Ashman K; Simons K; Stow J L
Myosin II is associated with Golgi membranes: identification of p200 as nonmuscle myosin II on Golgi-derived vesicles.
Journal of cell science 1997;110 ( Pt 18)():2155-64.
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1997: Verkade P; Simons K
Robert Feulgen Lecture 1997. Lipid microdomains and membrane trafficking in mammalian cells.
Histochemistry and cell biology 1997;108(3):211-20.
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1997: Scheiffele P; Roth M G; Simons K
Interaction of influenza virus haemagglutinin with sphingolipid-cholesterol membrane domains via its transmembrane domain.
The EMBO journal 1997;16(18):5501-8.
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1997: Harder T; Simons K
Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains.
Current opinion in cell biology 1997;9(4):534-42.
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1996: Eaton S; Wepf R; Simons K
Roles for Rac1 and Cdc42 in planar polarization and hair outgrowth in the wing of Drosophila.
The Journal of cell biology 1996;135(5):1277-89.
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1996: Peränen J; Auvinen P; Virta H; Wepf R; Simons K
Rab8 promotes polarized membrane transport through reorganization of actin and microtubules in fibroblasts.
The Journal of cell biology 1996;135(1):153-67.
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1996: Ikonen E; Parton R G; Lafont F; Simons K
Analysis of the role of p200-containing vesicles in post-Golgi traffic.
Molecular biology of the cell 1996;7(6):961-74.
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1996: Yoshimori T; Keller P; Roth M G; Simons K
Different biosynthetic transport routes to the plasma membrane in BHK and CHO cells.
The Journal of cell biology 1996;133(2):247-56.
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1996: Fiedler K; Simons K
Characterization of VIP36, an animal lectin homologous to leguminous lectins.
Journal of cell science 1996;109 ( Pt 1)():271-6.
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1995: Zacchetti D; Peränen J; Murata M; Fiedler K; Simons K
VIP17/MAL, a proteolipid in apical transport vesicles.
FEBS letters 1995;377(3):465-9.
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1995: Fra A M; Masserini M; Palestini P; Sonnino S; Simons K
A photo-reactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface.
FEBS letters 1995;375(1-2):11-4.
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1995: Scheiffele P; Peränen J; Simons K
N-glycans as apical sorting signals in epithelial cells.
Nature 1995;378(6552):96-8.
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1995: Murata M; Peränen J; Schreiner R; Wieland F; Kurzchalia T V; Simons K
VIP21/caveolin is a cholesterol-binding protein.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(22):10339-43.
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1995: Parton R G; Simons K
Digging into caveolae.
Science (New York, N.Y.) 1995;269(5229):1398-9.
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1995: Fra A M; Williamson E; Simons K; Parton R G
De novo formation of caveolae in lymphocytes by expression of VIP21-caveolin.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(19):8655-9.
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1995: Eaton S; Simons K
Apical, basal, and lateral cues for epithelial polarization.
Cell 1995;82(1):5-8.
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1995: Cid-Arregui A; Parton R G; Simons K; Dotti C G
Nocodazole-dependent transport, and brefeldin A--sensitive processing and sorting, of newly synthesized membrane proteins in cultured neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(6):4259-69.
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1995: Bucci C; Lütcke A; Steele-Mortimer O; Olkkonen V M; Dupree P; Chiariello M; Bruni C B; Simons K; Zerial M
Co-operative regulation of endocytosis by three Rab5 isoforms.
FEBS letters 1995;366(1):65-71.
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1995: Ikonen E; Tagaya M; Ullrich O; Montecucco C; Simons K
Different requirements for NSF, SNAP, and Rab proteins in apical and basolateral transport in MDCK cells.
Cell 1995;81(4):571-80.
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1995: Fiedler K; Simons K
The role of N-glycans in the secretory pathway.
Cell 1995;81(3):309-12.
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1995: Lütcke A; Olkkonen V M; Dupree P; Lütcke H; Simons K; Zerial M
Isolation of a murine cDNA clone encoding Rab19, a novel tissue-specific small GTPase.
Gene 1995;155(2):257-60.
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1995: Fiedler K; Lafont F; Parton R G; Simons K
Annexin XIIIb: a novel epithelial specific annexin is implicated in vesicular traffic to the apical plasma membrane.
The Journal of cell biology 1995;128(6):1043-53.
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1995: Ikonen E; Fiedler K; Parton R G; Simons K
Prohibitin, an antiproliferative protein, is localized to mitochondria.
FEBS letters 1995;358(3):273-7.
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1995: Lafont F; Simons K; Ikonen E
Dissecting the molecular mechanisms of polarized membrane traffic: reconstitution of three transport steps in epithelial cells using streptolysin-O permeabilization.
Cold Spring Harbor symposia on quantitative biology 1995;60():753-62.
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1994: Lafont F; Burkhardt J K; Simons K
Involvement of microtubule motors in basolateral and apical transport in kidney cells.
Nature 1994;372(6508):801-3.
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1994: Fra A M; Williamson E; Simons K; Parton R G
Detergent-insoluble glycolipid microdomains in lymphocytes in the absence of caveolae.
The Journal of biological chemistry 1994;269(49):30745-8.
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1994: Parton R G; Joggerst B; Simons K
Regulated internalization of caveolae.
The Journal of cell biology 1994;127(5):1199-215.
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1994: Lütcke A; Parton R G; Murphy C; Olkkonen V M; Dupree P; Valencia A; Simons K; Zerial M
Cloning and subcellular localization of novel rab proteins reveals polarized and cell type-specific expression.
Journal of cell science 1994;107 ( Pt 12)():3437-48.
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1994: Pimplikar S W; Simons K
Activators of protein kinase A stimulate apical but not basolateral transport in epithelial Madin-Darby canine kidney cells.
The Journal of biological chemistry 1994;269(29):19054-9.
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1994: Pimplikar S W; Ikonen E; Simons K
Basolateral protein transport in streptolysin O-permeabilized MDCK cells.
The Journal of cell biology 1994;125(5):1025-35.
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1994: Huber L A; Madison D L; Simons K; Pfeiffer S E
Myelin membrane biogenesis by oligodendrocytes. Developmental regulation of low molecular weight GTP-binding proteins.
FEBS letters 1994;347(2-3):273-8.
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1994: Fiedler K; Parton R G; Kellner R; Etzold T; Simons K
VIP36, a novel component of glycolipid rafts and exocytic carrier vesicles in epithelial cells.
The EMBO journal 1994;13(7):1729-40.
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1994: Huber L A; Beug H; Simons K; Reichmann E
Two-dimensional gel mapping of small GTPases reveals transformation-specific changes during oncogenesis.
Electrophoresis 1994;15(3-4):469-73.
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1994: Olkkonen V M; Peterson J R; Dupree P; Lütcke A; Zerial M; Simons K
Isolation of a mouse cDNA encoding Rab23, a small novel GTPase expressed predominantly in the brain.
Gene 1994;138(1-2):207-11.
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1994: Olkkonen V M; Dupree P; Simons K; Liljeström P; Garoff H
Expression of exogenous proteins in mammalian cells with the Semliki Forest virus vector.
Methods in cell biology 1994;43 Pt A():43-53.
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1993: Olkkonen V M; Dupree P; Killisch I; Lütcke A; Zerial M; Simons K
Molecular cloning and subcellular localization of three GTP-binding proteins of the rab subfamily.
Journal of cell science 1993;106 ( Pt 4)():1249-61.
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1993: Simons K; Zerial M
Rab proteins and the road maps for intracellular transport.
Neuron 1993;11(5):789-99.
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1993: Ikonen E; Parton R G; Hunziker W; Simons K; Dotti C G
Transcytosis of the polymeric immunoglobulin receptor in cultured hippocampal neurons.
Current biology : CB 1993;3(10):635-44.
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1993: Huber L A; de Hoop M J; Dupree P; Zerial M; Simons K; Dotti C
Protein transport to the dendritic plasma membrane of cultured neurons is regulated by rab8p.
The Journal of cell biology 1993;123(1):47-55.
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1993: Huber L A; Pimplikar S; Parton R G; Virta H; Zerial M; Simons K
Rab8, a small GTPase involved in vesicular traffic between the TGN and the basolateral plasma membrane.
The Journal of cell biology 1993;123(1):35-45.
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1993: Olkkonen V M; Liljeström P; Garoff H; Simons K; Dotti C G
Expression of heterologous proteins in cultured rat hippocampal neurons using the Semliki Forest virus vector.
Journal of neuroscience research 1993;35(4):445-51.
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1993: Fiedler K; Kobayashi T; Kurzchalia T V; Simons K
Glycosphingolipid-enriched, detergent-insoluble complexes in protein sorting in epithelial cells.
Biochemistry 1993;32(25):6365-73.
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1993: Dotti C G; Kartenbeck J; Simons K
Polarized distribution of the viral glycoproteins of vesicular stomatitis, fowl plague and Semliki Forest viruses in hippocampal neurons in culture: a light and electron microscopy study.
Brain research 1993;610(1):141-7.
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1993: Dupree P; Parton R G; Raposo G; Kurzchalia T V; Simons K
Caveolae and sorting in the trans-Golgi network of epithelial cells.
The EMBO journal 1993;12(4):1597-605.
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1993: Pimplikar S W; Simons K
Regulation of apical transport in epithelial cells by a Gs class of heterotrimeric G protein.
Nature 1993;362(6419):456-8.
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1993: Pimplikar S W; Simons K
Role of heterotrimeric G proteins in polarized membrane transport.
Journal of cell science. Supplement 1993;17():27-32.
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1992: Parton R G; Simons K; Dotti C G
Axonal and dendritic endocytic pathways in cultured neurons.
The Journal of cell biology 1992;119(1):123-37.
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1992: Kobayashi T; Storrie B; Simons K; Dotti C G
A functional barrier to movement of lipids in polarized neurons.
Nature 1992;359(6396):647-50.
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1992: Kurzchalia T V; Gorvel J P; Dupree P; Parton R; Kellner R; Houthaeve T; Gruenberg J; Simons K
Interactions of rab5 with cytosolic proteins.
The Journal of biological chemistry 1992;267(26):18419-23.
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1992: Bucci C; Parton R G; Mather I H; Stunnenberg H; Simons K; Hoflack B; Zerial M
The small GTPase rab5 functions as a regulatory factor in the early endocytic pathway.
Cell 1992;70(5):715-28.
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1992: Kurzchalia T V; Dupree P; Parton R G; Kellner R; Virta H; Lehnert M; Simons K
VIP21, a 21-kD membrane protein is an integral component of trans-Golgi-network-derived transport vesicles.
The Journal of cell biology 1992;118(5):1003-14.
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1992: Kobayashi T; Pimplikar S W; Parton R G; Bhakdi S; Simons K
Sphingolipid transport from the trans-Golgi network to the apical surface in permeabilized MDCK cells.
FEBS letters 1992;300(3):227-31.
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1992: Chavrier P; Simons K; Zerial M
The complexity of the Rab and Rho GTP-binding protein subfamilies revealed by a PCR cloning approach.
Gene 1992;112(2):261-4.
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1992: Simons K; Dupree P; Fiedler K; Huber L A; Kobayashi T; Kurzchalia T; Olkkonen V; Pimplikar S; Parton R; Dotti C
Biogenesis of cell-surface polarity in epithelial cells and neurons.
Cold Spring Harbor symposia on quantitative biology 1992;57():611-9.
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1991: Chavrier P; Gorvel J P; Stelzer E; Simons K; Gruenberg J; Zerial M
Hypervariable C-terminal domain of rab proteins acts as a targeting signal.
Nature 1991;353(6346):769-72.
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1991: Parton R G; Simons K
Endocytosis in the kidney: insights from the MDCK cell system.
Seminars in nephrology 1991;11(4):440-52.
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1991: Brändli A W; Adamson E D; Simons K
Transcytosis of epidermal growth factor. The epidermal growth factor receptor mediates uptake but not transcytosis.
The Journal of biological chemistry 1991;266(13):8560-6.
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1991: Parton R G; Dotti C G; Bacallao R; Kurtz I; Simons K; Prydz K
pH-induced microtubule-dependent redistribution of late endosomes in neuronal and epithelial cells.
The Journal of cell biology 1991;113(2):261-74.
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1991: Dotti C G; Parton R G; Simons K
Polarized sorting of glypiated proteins in hippocampal neurons.
Nature 1991;349(6305):158-61.
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1990: Brändli A W; Parton R G; Simons K
Transcytosis in MDCK cells: identification of glycoproteins transported bidirectionally between both plasma membrane domains.
The Journal of cell biology 1990;111(6 Pt 2):2909-21.
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1990: Chavrier P; Vingron M; Sander C; Simons K; Zerial M
Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line.
Molecular and cellular biology 1990;10(12):6578-85.
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1990: Wandinger-Ness A; Bennett M K; Antony C; Simons K
Distinct transport vesicles mediate the delivery of plasma membrane proteins to the apical and basolateral domains of MDCK cells.
The Journal of cell biology 1990;111(3):987-1000.
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1990: Simons K; Wandinger-Ness A
Polarized sorting in epithelia.
Cell 1990;62(2):207-10.
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1990: Dotti C G; Simons K
Polarized sorting of viral glycoproteins to the axon and dendrites of hippocampal neurons in culture.
Cell 1990;62(1):63-72.
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1990: Chavrier P; Parton R G; Hauri H P; Simons K; Zerial M
Localization of low molecular weight GTP binding proteins to exocytic and endocytic compartments.
Cell 1990;62(2):317-29.
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1990: Prydz K; Brändli A W; Bomsel M; Simons K
Surface distribution of the mannose 6-phosphate receptors in epithelial Madin-Darby canine kidney cells.
The Journal of biological chemistry 1990;265(21):12629-35.
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1990: Van der Sluijs P; Bennett M K; Antony C; Simons K; Kreis T E
Binding of exocytic vesicles from MDCK cells to microtubules in vitro.
Journal of cell science 1990;95 ( Pt 4)():545-53.
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1989: Bomsel M; Prydz K; Parton R G; Gruenberg J; Simons K
Endocytosis in filter-grown Madin-Darby canine kidney cells.
The Journal of cell biology 1989;109(6 Pt 2):3243-58.
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1989: Bacallao R; Antony C; Dotti C; Karsenti E; Stelzer E H; Simons K
The subcellular organization of Madin-Darby canine kidney cells during the formation of a polarized epithelium.
The Journal of cell biology 1989;109(6 Pt 1):2817-32.
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1989: Parton R G; Prydz K; Bomsel M; Simons K; Griffiths G
Meeting of the apical and basolateral endocytic pathways of the Madin-Darby canine kidney cell in late endosomes.
The Journal of cell biology 1989;109(6 Pt 2):3259-72.
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1989: Brändli A W; Simons K
A restricted set of apical proteins recycle through the trans-Golgi network in MDCK cells.
The EMBO journal 1989;8(11):3207-13.
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1989: de Curtis I; Simons K
Isolation of exocytic carrier vesicles from BHK cells.
Cell 1989;58(4):719-27.
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1989: Griffiths G; Fuller S D; Back R; Hollinshead M; Pfeiffer S; Simons K
The dynamic nature of the Golgi complex.
The Journal of cell biology 1989;108(2):277-97.
-
1989: Bennett M K; Wandinger-Ness A; De Curtis I; Antony C; Simons K; Kartenbeck J
Perforated cells for studying intracellular membrane transport.
Methods in cell biology 1989;31():103-26.
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1988: Bennett M K; Wandinger-Ness A; Simons K
Release of putative exocytic transport vesicles from perforated MDCK cells.
The EMBO journal 1988;7(13):4075-85.
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1988: de Curtis I; Simons K
Dissection of Semliki Forest virus glycoprotein delivery from the trans-Golgi network to the cell surface in permeabilized BHK cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(21):8052-6.
-
1988: Brändli A W; Hansson G C; Rodriguez-Boulan E; Simons K
A polarized epithelial cell mutant deficient in translocation of UDP-galactose into the Golgi complex.
The Journal of biological chemistry 1988;263(31):16283-90.
-
1988: Simons K; van Meer G
Lipid sorting in epithelial cells.
Biochemistry 1988;27(17):6197-202.
-
1988: de Curtis I; Howell K E; Simons K
Isolation of a fraction enriched in the trans-Golgi network from baby hamster kidney cells.
Experimental cell research 1988;175(2):248-65.
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1988: Griffiths G; Hoflack B; Simons K; Mellman I; Kornfeld S
The mannose 6-phosphate receptor and the biogenesis of lysosomes.
Cell 1988;52(3):329-41.
-
1988: de Curtis I; Simons K
Characterization of the trans-Golgi network in BHK cells.
Progress in clinical and biological research 1988;270():101-13.
-
1987: Simons K
Membrane traffic in an epithelial cell line derived from the dog kidney.
Kidney international. Supplement 1987;23():S201-10.
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1987: van Meer G; Stelzer E H; Wijnaendts-van-Resandt R W; Simons K
Sorting of sphingolipids in epithelial (Madin-Darby canine kidney) cells.
The Journal of cell biology 1987;105(4):1623-35.
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1987: Simons K; Virta H
Perforated MDCK cells support intracellular transport.
The EMBO journal 1987;6(8):2241-7.
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