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Evan Simpson

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

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Co-Publications
Name
31
Jones, Margaret
28
Mendelson, Carole
25
Bulun, Serdar
19
Boon, Wah Chin
16
Clyne, Colin
15
Zhao, Y
13
Britt, Kara
13
Mahendroo, Mala
10
Hinshelwood, Margaret
10
Agarwal, VR
10
Corbin, Jo
9
Findlay, Jock
8
Michael, Dodson
8
Misso, Marie
7
McPhaul, Michael

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Publications

TOP 3
Chow Jenny D Y; Simpson Evan R; Boon Wah Chin
Alternative 5'-untranslated first exons of the mouse Cyp19A1 (aromatase) gene.
Simpson Evan R
Estrogens and the brain. Preface.
Hill Rachel A; Chua Hui Kheng; Jones Margaret E E; Simpson Evan R; Boon Wah Chin
Estrogen deficiency results in apoptosis in the frontal cortex of adult female aromatase knockout mice.

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All Publications

2009: Chow Jenny D Y; Simpson Evan R; Boon Wah Chin
Alternative 5'-untranslated first exons of the mouse Cyp19A1 (aromatase) gene.
The Journal of steroid biochemistry and molecular biology 2009;115(3-5):115-25.
2009: Simpson Evan R
Estrogens and the brain. Preface.
Seminars in reproductive medicine 2009;27(3):205.
2009: Hill Rachel A; Chua Hui Kheng; Jones Margaret E E; Simpson Evan R; Boon Wah Chin
Estrogen deficiency results in apoptosis in the frontal cortex of adult female aromatase knockout mice.
Molecular and cellular neurosciences 2009;41(1):1-7.
2009: Van Sinderen Michelle L; Boon Wah Chin; Ederveen Antwan G H; Kloosterboer Helenius J; Simpson Evan R; Jones Margaret E E
The estrogenic component of tibolone reduces adiposity in female aromatase knockout mice.
Menopause (New York, N.Y.) 2009;16(3):582-8.
2009: Chand Ashwini L; Simpson Evan R; Clyne Colin D
Aromatase expression is increased in BRCA1 mutation carriers.
BMC cancer 2009;9():148.
2008: McInnes Kerry J; Brown Kristy A; Knower Kevin C; Chand Ashwini L; Clyne Colin D; Simpson Evan R
Characterisation of aromatase expression in the human adipocyte cell line SGBS.
Breast cancer research and treatment 2008;112(3):429-35.
2008: Bayne Sharyn; Jones Margaret Ee; Li He; Pinto Alex R; Simpson Evan R; Liu Jun-Ping
Estrogen deficiency leads to telomerase inhibition, telomere shortening and reduced cell proliferation in the adrenal gland of mice.
Cell research 2008;18(11):1141-50.
2007: Gray Katherine T; Short Jennifer L; Simpson Evan R; Ventura Sabatino
The effects of targeted deletion of the aromatase enzyme on prostatic contractile responses to noradrenaline in mice.
The Journal of endocrinology 2007;195(3):495-502.
2007: Hill Rachel A; Chow Jenny; Fritzemeier Karlheinrich; Simpson Evan R; Boon Wah Chin
Fas/FasL-mediated apoptosis in the arcuate nucleus and medial preoptic area of male ArKO mice is ameliorated by selective estrogen receptor alpha and estrogen receptor beta agonist treatment, respectively.
Molecular and cellular neurosciences 2007;36(2):146-57.
2007: Jones M E E; McInnes K J; Boon W C; Simpson E R
Estrogen and adiposity--utilizing models of aromatase deficiency to explore the relationship.
The Journal of steroid biochemistry and molecular biology 2007;106(1-5):3-7.
2007: Jones Margaret E E; Boon Wah Chin; McInnes Kerry; Maffei Laura; Carani Cesare; Simpson Evan R
Recognizing rare disorders: aromatase deficiency.
Nature clinical practice. Endocrinology & metabolism 2007;3(5):414-21.
2007: Hill Rachel A; McInnes Kerry J; Gong Emily C H; Jones Margaret E E; Simpson Evan R; Boon Wah Chin
Estrogen deficient male mice develop compulsive behavior.
Biological psychiatry 2007;61(3):359-66.
2006: McInnes Kerry J; Corbould Anne; Simpson Evan R; Jones Margaret E
Regulation of adenosine 5',monophosphate-activated protein kinase and lipogenesis by androgens contributes to visceral obesity in an estrogen-deficient state.
Endocrinology 2006;147(12):5907-13.
2006: Plackett Timothy P; Oz Orhan K; Simpson Evan R; Kovacs Elizabeth J
Lack of aromatase improves cell-mediated immune response after burn.
Burns : journal of the International Society for Burn Injuries 2006;32(5):577-82.
2006: Pathirage Niroshani; Di Nezza Lisa A; Salmonsen Lois A; Jobling Tom; Simpson Evan R; Clyne Colin D
Expression of aromatase, estrogen receptors, and their coactivators in patients with endometrial cancer.
Fertility and sterility 2006;86(2):469-72.
2006: Jones Margaret E E; Boon Wah Chin; Proietto Joseph; Simpson Evan R
Of mice and men: the evolving phenotype of aromatase deficiency.
Trends in endocrinology and metabolism: TEM 2006;17(2):55-64.
2006: Simpson E R; Jones M E
Of mice and men: the many guises of estrogens.
Ernst Schering Foundation symposium proceedings 2006;(1):45-67.
2005: Safi Rachid; Kovacic Agnes; Gaillard Stéphanie; Murata Yoko; Simpson Evan R; McDonnell Donald P; Clyne Colin D
Coactivation of liver receptor homologue-1 by peroxisome proliferator-activated receptor gamma coactivator-1alpha on aromatase promoter II and its inhibition by activated retinoid X receptor suggest a novel target for breast-specific antiestrogen therapy.
Cancer research 2005;65(24):11762-70.
2005: Simpson Evan R; McInnes Kerry J
Sex and fat--can one factor handle both?
Cell metabolism 2005;2(6):346-7.
2005: Boon Wah Chin; Diepstraten Jeroen; van der Burg Jorien; Jones Margaret E E; Simpson Evan R; van den Buuse Maarten
Hippocampal NMDA receptor subunit expression and watermaze learning in estrogen deficient female mice.
Brain research. Molecular brain research 2005;140(1-2):127-32.
2005: Misso Marie L; Jang Christina; Adams Jennifer; Tran Jane; Murata Yoko; Bell Robin; Boon Wah Chin; Simpson Evan R; Davis Susan R
Differential expression of factors involved in fat metabolism with age and the menopause transition.
Maturitas 2005;51(3):299-306.
2005: Simpson E R; Misso M; Hewitt K N; Hill R A; Boon W C; Jones M E; Kovacic A; Zhou J; Clyne C D
Estrogen--the good, the bad, and the unexpected.
Endocrine reviews 2005;26(3):322-30.
2005: Misso Marie L; Jang Christina; Adams Jennifer; Tran Jane; Murata Yoko; Bell Robin; Boon Wah Chin; Simpson Evan R; Davis Susan R
Adipose aromatase gene expression is greater in older women and is unaffected by postmenopausal estrogen therapy.
Menopause (New York, N.Y.) 2005;12(2):210-5.
2005: Britt Kara L; Simpson Evan R; Findlay Jock K
Effects of phytoestrogens on the ovarian and pituitary phenotypes of estrogen-deficient female aromatase knockout mice.
Menopause (New York, N.Y.) 2005;12(2):174-85.
2005: Misso M L; Hewitt K N; Boon W C; Murata Y; Jones M E E; Simpson E R
Cholesterol feeding prevents adiposity in the obese female aromatase knockout (ArKO) mouse.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2005;37(1):26-31.
2005: Zhou Jiong; Suzuki Takashi; Kovacic Agnes; Saito Ryoko; Miki Yasuhiro; Ishida Takanori; Moriya Takuya; Simpson Evan R; Sasano Hironobu; Clyne Colin D
Interactions between prostaglandin E(2), liver receptor homologue-1, and aromatase in breast cancer.
Cancer research 2005;65(2):657-63.
2005: Yan Ming; Jones Margaret E E; Hernandez Maria; Liu Dongling; Simpson Evan R; Chen Chen
Oestrogen replacement in vivo rescues the dysfunction of pituitary somatotropes in ovariectomised aromatase knockout mice.
Neuroendocrinology 2005;81(3):158-66.
2004: Hill Rachel A; Pompolo Sueli; Jones Margaret E E; Simpson Evan R; Boon Wah Chin
Estrogen deficiency leads to apoptosis in dopaminergic neurons in the medial preoptic area and arcuate nucleus of male mice.
Molecular and cellular neurosciences 2004;27(4):466-76.
2004: Britt Kara L; Saunders Philippa K; McPherson Stephen J; Misso Marie L; Simpson Evan R; Findlay Jock K
Estrogen actions on follicle formation and early follicle development.
Biology of reproduction 2004;71(5):1712-23.
2004: Britt Kara L; Stanton Peter G; Misso Marie; Simpson Evan R; Findlay Jock K
The effects of estrogen on the expression of genes underlying the differentiation of somatic cells in the murine gonad.
Endocrinology 2004;145(8):3950-60.
2004: Pezzi Vincenzo; Sirianni Rosa; Chimento Adele; Maggiolini Marcello; Bourguiba Sonia; Delalande Christelle; Carreau Serge; Andò Sebastiano; Simpson Evan R; Clyne Colin D
Differential expression of steroidogenic factor-1/adrenal 4 binding protein and liver receptor homolog-1 (LRH-1)/fetoprotein transcription factor in the rat testis: LRH-1 as a potential regulator of testicular aromatase expression.
Endocrinology 2004;145(5):2186-96.
2004: Watanabe M; Simpson E R; Pathirage N; Nakajin S; Clyne C D
Aromatase expression in the human fetal osteoblastic cell line SV-HFO.
Journal of molecular endocrinology 2004;32(2):533-45.
2004: Hewitt Kylie N; Pratis Kyriakos; Jones Margaret E E; Simpson Evan R
Estrogen replacement reverses the hepatic steatosis phenotype in the male aromatase knockout mouse.
Endocrinology 2004;145(4):1842-8.
2004: Simpson Evan R
Models of aromatase insufficiency.
Seminars in reproductive medicine 2004;22(1):25-30.
2004: Simpson Evan R
Aromatase: biologic relevance of tissue-specific expression.
Seminars in reproductive medicine 2004;22(1):11-23.
2004: Clyne Colin D; Kovacic Agnes; Speed Caroline J; Zhou Jiong; Pezzi Vincenzo; Simpson Evan R
Regulation of aromatase expression by the nuclear receptor LRH-1 in adipose tissue.
Molecular and cellular endocrinology 2004;215(1-2):39-44.
2004: Yan Ming; Jones Margaret E E; Hernandez Maria; Liu Dongling; Simpson Evan R; Chen Chen
Functional modification of pituitary somatotropes in the aromatase knockout mouse and the effect of estrogen replacement.
Endocrinology 2004;145(2):604-12.
2004: Kovacic Agnes; Speed Caroline J; Simpson Evan R; Clyne Colin D
Inhibition of aromatase transcription via promoter II by short heterodimer partner in human preadipocytes.
Molecular endocrinology (Baltimore, Md.) 2004;18(1):252-9.
2004: Simpson E R; McPherson S; Jones M; Robertson K; Boon W C; Risbridger G
Role of estrogens in the male reproductive tract.
Ernst Schering Research Foundation workshop 2004;(46):89-112.
2003: McCullough Louise D; Blizzard Kathleen; Simpson Evan R; Oz Orhan K; Hurn Patricia D
Aromatase cytochrome P450 and extragonadal estrogen play a role in ischemic neuroprotection.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(25):8701-5.
2003: Hewitt Kylie N; Boon Wah Chin; Murata Yoko; Jones Margaret E E; Simpson Evan R
The aromatase knockout mouse presents with a sexually dimorphic disruption to cholesterol homeostasis.
Endocrinology 2003;144(9):3895-903.
2003: Sofi Mariam; Young Morag J; Papamakarios Theodora; Simpson Evan R; Clyne Colin D
Role of CRE-binding protein (CREB) in aromatase expression in breast adipose.
Breast cancer research and treatment 2003;79(3):399-407.
2003: Misso Marie L; Murata Yoko; Boon Wah Chin; Jones Margaret E E; Britt Kara L; Simpson Evan R
Cellular and molecular characterization of the adipose phenotype of the aromatase-deficient mouse.
Endocrinology 2003;144(4):1474-80.
2002: Karuppu Darshini; Kalus Alan; Simpson Evan R; Clyne Colin
Aromatase and prostaglandin inter-relationships in breast adipose tissue: significance for breast cancer development.
Breast cancer research and treatment 2002;76(2):103-9.
2002: Britt Kara L; Kerr Jeff; O'Donnell Liza; Jones Margaret E E; Drummond Ann E; Davis Susan R; Simpson Evan R; Findlay Jock K
Estrogen regulates development of the somatic cell phenotype in the eutherian ovary.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(11):1389-97.
2002: Robertson Kirsten M; O'Donnell Liza; Simpson Evan R; Jones Margaret E E
The phenotype of the aromatase knockout mouse reveals dietary phytoestrogens impact significantly on testis function.
Endocrinology 2002;143(8):2913-21.
2002: Rubin Gary L; Duong Jenny H; Clyne Colin D; Speed Caroline J; Murata Yoko; Gong Changhong; Simpson Evan R
Ligands for the peroxisomal proliferator-activated receptor gamma and the retinoid X receptor inhibit aromatase cytochrome P450 (CYP19) expression mediated by promoter II in human breast adipose.
Endocrinology 2002;143(8):2863-71.
2002: Murata Y; Robertson K M; Jones M E E; Simpson E R
Effect of estrogen deficiency in the male: the ArKO mouse model.
Molecular and cellular endocrinology 2002;193(1-2):7-12.
2002: Clyne Colin D; Speed Caroline J; Zhou Jiong; Simpson Evan R
Liver receptor homologue-1 (LRH-1) regulates expression of aromatase in preadipocytes.
The Journal of biological chemistry 2002;277(23):20591-7.
2002: Drummond Ann E; Britt Kara L; Dyson Mitzi; Jones Margaret E; Kerr Jeff B; O'Donnell Liza; Simpson Evan R; Findlay Jock K
Ovarian steroid receptors and their role in ovarian function.
Molecular and cellular endocrinology 2002;191(1):27-33.
2002: Simpson Evan R
Aromatization of androgens in women: current concepts and findings.
Fertility and sterility 2002;77 Suppl 4():S6-10.
2002: Simpson Evan R; Dowsett Mitch
Aromatase and its inhibitors: significance for breast cancer therapy.
Recent progress in hormone research 2002;57():317-38.
2002: Simpson Evan R; Clyne Colin; Rubin Gary; Boon Wah Chin; Robertson Kirsten; Britt Kara; Speed Caroline; Jones Margaret
Aromatase--a brief overview.
Annual review of physiology 2002;64():93-127.
2001: Britt K L; Drummond A E; Dyson M; Wreford N G; Jones M E; Simpson E R; Findlay J K
The ovarian phenotype of the aromatase knockout (ArKO) mouse.
The Journal of steroid biochemistry and molecular biology 2001;79(1-5):181-5.
2001: Oz O K; Hirasawa G; Lawson J; Nanu L; Constantinescu A; Antich P P; Mason R P; Tsyganov E; Parkey R W; Zerwekh J E; Simpson E R
Bone phenotype of the aromatase deficient mouse.
The Journal of steroid biochemistry and molecular biology 2001;79(1-5):49-59.
2001: Jones M E; Thorburn A W; Britt K L; Hewitt K N; Misso M L; Wreford N G; Proietto J; Oz O K; Leury B J; Robertson K M; Yao S; Simpson E R
Aromatase-deficient (ArKO) mice accumulate excess adipose tissue.
The Journal of steroid biochemistry and molecular biology 2001;79(1-5):3-9.
2001: Simpson E R; Clyne C; Speed C; Rubin G; Bulun S
Tissue-specific estrogen biosynthesis and metabolism.
Annals of the New York Academy of Sciences 2001;949():58-67.
2001: Robertson K M; Simpson E R; Lacham-Kaplan O; Jones M E
Characterization of the fertility of male aromatase knockout mice.
Journal of andrology 2001;22(5):825-30.
2001: O'Donnell L; Robertson K M; Jones M E; Simpson E R
Estrogen and spermatogenesis.
Endocrine reviews 2001;22(3):289-318.
2001: Findlay J K; Britt K; Kerr J B; O'Donnell L; Jones M E; Drummond A E; Simpson E R
The road to ovulation: the role of oestrogens.
Reproduction, fertility, and development 2001;13(7-8):543-7.
2000: Simpson E R; Davis S R
Another role highlighted for estrogens in the male: sexual behavior.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14038-40.
2000: Jones M E; Thorburn A W; Britt K L; Hewitt K N; Wreford N G; Proietto J; Oz O K; Leury B J; Robertson K M; Yao S; Simpson E R
Aromatase-deficient (ArKO) mice have a phenotype of increased adiposity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12735-40.
2000: Simpson E R
Role of aromatase in sex steroid action.
Journal of molecular endocrinology 2000;25(2):149-56.
2000: Jones M E; Simpson E R
Oestrogens in male reproduction.
Baillière's best practice & research. Clinical endocrinology & metabolism 2000;14(3):505-16.
2000: Simpson E R
Biology of aromatase in the mammary gland.
Journal of mammary gland biology and neoplasia 2000;5(3):251-8.
2000: Britt K L; Drummond A E; Cox V A; Dyson M; Wreford N G; Jones M E; Simpson E R; Findlay J K
An age-related ovarian phenotype in mice with targeted disruption of the Cyp 19 (aromatase) gene.
Endocrinology 2000;141(7):2614-23.
2000: Findlay J K; Drummond A E; Britt K L; Dyson M; Wreford N G; Robertson D M; Groome N P; Jones M E; Simpson E R
The roles of activins, inhibins and estrogen in early committed follicles.
Molecular and cellular endocrinology 2000;163(1-2):81-7.
2000: Agarwal V R; Sinton C M; Liang C; Fisher C; German D C; Simpson E R
Upregulation of estrogen receptors in the forebrain of aromatase knockout (ArKO) mice.
Molecular and cellular endocrinology 2000;162(1-2):9-16.
2000: Oz O K; Zerwekh J E; Fisher C; Graves K; Nanu L; Millsaps R; Simpson E R
Bone has a sexually dimorphic response to aromatase deficiency.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(3):507-14.
2000: Shozu M; Zhao Y; Simpson E R
TGF-beta1 stimulates expression of the aromatase (CYP19) gene in human osteoblast-like cells and THP-1 cells.
Molecular and cellular endocrinology 2000;160(1-2):123-33.
1999: Liu Z; Simpson E R
Molecular mechanism for cooperation between Sp1 and steroidogenic factor-1 (SF-1) to regulate bovine CYP11A gene expression.
Molecular and cellular endocrinology 1999;153(1-2):183-96.
1999: Robertson K M; O'Donnell L; Jones M E; Meachem S J; Boon W C; Fisher C R; Graves K H; McLachlan R I; Simpson E R
Impairment of spermatogenesis in mice lacking a functional aromatase (cyp 19) gene.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(14):7986-91.
1998: Simpson E R
Genetic mutations resulting in estrogen insufficiency in the male.
Molecular and cellular endocrinology 1998;145(1-2):55-9.
1998: Fisher C R; Graves K H; Parlow A F; Simpson E R
Characterization of mice deficient in aromatase (ArKO) because of targeted disruption of the cyp19 gene.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(12):6965-70.
1998: Agarwal V R; Takayama K; Van Wyk J J; Sasano H; Simpson E R; Bulun S E
Molecular basis of severe gynecomastia associated with aromatase expression in a fibrolamellar hepatocellular carcinoma.
The Journal of clinical endocrinology and metabolism 1998;83(5):1797-800.
1998: Shozu M; Simpson E R
Aromatase expression of human osteoblast-like cells.
Molecular and cellular endocrinology 1998;139(1-2):117-29.
1998: Sun T; Zhao Y; Mangelsdorf D J; Simpson E R
Characterization of a region upstream of exon I.1 of the human CYP19 (aromatase) gene that mediates regulation by retinoids in human choriocarcinoma cells.
Endocrinology 1998;139(4):1684-91.
1998: Shozu M; Zhao Y; Bulun S E; Simpson E R
Multiple splicing events involved in regulation of human aromatase expression by a novel promoter, I.6.
Endocrinology 1998;139(4):1610-7.
1997: Shozu M; Zhao Y; Simpson E R
Estrogen biosynthesis in THP1 cells is regulated by promoter switching of the aromatase (CYP19) gene.
Endocrinology 1997;138(12):5125-35.
1997: Michael M D; Michael L F; Simpson E R
A CRE-like sequence that binds CREB and contributes to cAMP-dependent regulation of the proximal promoter of the human aromatase P450 (CYP19) gene.
Molecular and cellular endocrinology 1997;134(2):147-56.
1997: Hinshelwood M M; Michael M D; Simpson E R
The 5'-flanking region of the ovarian promoter of the bovine CYP19 gene contains a deletion in a cyclic adenosine 3',5'-monophosphate-like responsive sequence.
Endocrinology 1997;138(9):3704-10.
1997: Borroni R; Liu Z; Simpson E R; Hinshelwood M M
A putative binding site for Sp1 is involved in transcriptional regulation of CYP17 gene expression in bovine ovary.
Endocrinology 1997;138(5):2011-20.
1997: Hinshelwood M M; Dodson Michael M; Sun T; Simpson E R
Regulation of aromatase expression in the ovary and placenta: a comparison between two species.
The Journal of steroid biochemistry and molecular biology 1997;61(3-6):399-405.
1997: Zhao Y; Agarwal V R; Mendelson C R; Simpson E R
Transcriptional regulation of CYP19 gene (aromatase) expression in adipose stromal cells in primary culture.
The Journal of steroid biochemistry and molecular biology 1997;61(3-6):203-10.
1997: Bulun S E; Noble L S; Takayama K; Michael M D; Agarwal V; Fisher C; Zhao Y; Hinshelwood M M; Ito Y; Simpson E R
Endocrine disorders associated with inappropriately high aromatase expression.
The Journal of steroid biochemistry and molecular biology 1997;61(3-6):133-9.
1997: Liu Z; Simpson E R
Steroidogenic factor 1 (SF-1) and SP1 are required for regulation of bovine CYP11A gene expression in bovine luteal cells and adrenal Y1 cells.
Molecular endocrinology (Baltimore, Md.) 1997;11(2):127-37.
1997: Simpson E R; Michael M D; Agarwal V R; Hinshelwood M M; Bulun S E; Zhao Y
Cytochromes P450 11: expression of the CYP19 (aromatase) gene: an unusual case of alternative promoter usage.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1997;11(1):29-36.
1997: Agarwal V R; Ashanullah C I; Simpson E R; Bulun S E
Alternatively spliced transcripts of the aromatase cytochrome P450 (CYP19) gene in adipose tissue of women.
The Journal of clinical endocrinology and metabolism 1997;82(1):70-4.
1997: Simpson E R; Zhao Y; Agarwal V R; Michael M D; Bulun S E; Hinshelwood M M; Graham-Lorence S; Sun T; Fisher C R; Qin K; Mendelson C R
Aromatase expression in health and disease.
Recent progress in hormone research 1997;52():185-213; discussion 213-4.
1996: Zhao Y; Agarwal V R; Mendelson C R; Simpson E R
Estrogen biosynthesis proximal to a breast tumor is stimulated by PGE2 via cyclic AMP, leading to activation of promoter II of the CYP19 (aromatase) gene.
Endocrinology 1996;137(12):5739-42.
1996: Agarwal V R; Bulun S E; Leitch M; Rohrich R; Simpson E R
Use of alternative promoters to express the aromatase cytochrome P450 (CYP19) gene in breast adipose tissues of cancer-free and breast cancer patients.
The Journal of clinical endocrinology and metabolism 1996;81(11):3843-9.
1996: Zhao Y; Nichols J E; Valdez R; Mendelson C R; Simpson E R
Tumor necrosis factor-alpha stimulates aromatase gene expression in human adipose stromal cells through use of an activating protein-1 binding site upstream of promoter 1.4.
Molecular endocrinology (Baltimore, Md.) 1996;10(11):1350-7.
1996: Demeter Arlotto M; Michael M D; Kilgore M W; Simpson E R
17alpha-Hydroxylase gene expression in the bovine ovary: mechanisms regulating expression differ from those in adrenal cells.
The Journal of steroid biochemistry and molecular biology 1996;59(1):21-9.
1996: Simpson E R; Bulun S E; Nichols J E; Zhao Y
Estrogen biosynthesis in adipose tissue: regulation by paracrine and autocrine mechanisms.
The Journal of endocrinology 1996;150 Suppl():S51-7.
1996: Rink J D; Simpson E R; Barnard J J; Bulun S E
Cellular characterization of adipose tissue from various body sites of women.
The Journal of clinical endocrinology and metabolism 1996;81(7):2443-7.
1996: Amarneh B A; Simpson E R
Detection of aromatase cytochrome P450, 17 alpha-hydroxylase cytochrome P450 and NADPH:P450 reductase on the surface of cells in which they are expressed.
Molecular and cellular endocrinology 1996;119(1):69-74.
1996: Crichton M B; Nichols J E; Zhao Y; Bulun S E; Simpson E R
Expression of transcripts of interleukin-6 and related cytokines by human breast tumors, breast cancer cells, and adipose stromal cells.
Molecular and cellular endocrinology 1996;118(1-2):215-20.
1996: Simpson E R; Zhao Y
Estrogen biosynthesis in adipose. Significance in breast cancer development.
Annals of the New York Academy of Sciences 1996;784():18-26.
1996: Bulun S E; Sharda G; Rink J; Sharma S; Simpson E R
Distribution of aromatase P450 transcripts and adipose fibroblasts in the human breast.
The Journal of clinical endocrinology and metabolism 1996;81(3):1273-7.
1996: Conley A J; Corbin C J; Hinshelwood M M; Liu Z; Simpson E R; Ford J J; Harada N
Functional aromatase expression in porcine adrenal gland and testis.
Biology of reproduction 1996;54(2):497-505.
1996: Noble L S; Simpson E R; Johns A; Bulun S E
Aromatase expression in endometriosis.
The Journal of clinical endocrinology and metabolism 1996;81(1):174-9.
1995: Agarwal V R; Bulun S E; Simpson E R
Quantitative detection of alternatively spliced transcripts of the aromatase cytochrome P450 (CYP19) gene in aromatase-expressing human cells by competitive RT-PCR.
Molecular and cellular probes 1995;9(6):453-64.
1995: Hinshelwood M M; Liu Z; Conley A J; Simpson E R
Demonstration of tissue-specific promoters in nonprimate species that express aromatase P450 in placentae.
Biology of reproduction 1995;53(5):1151-9.
1995: Zhao Y; Nichols J E; Bulun S E; Mendelson C R; Simpson E R
Aromatase P450 gene expression in human adipose tissue. Role of a Jak/STAT pathway in regulation of the adipose-specific promoter.
The Journal of biological chemistry 1995;270(27):16449-57.
1995: Michael M D; Kilgore M W; Morohashi K; Simpson E R
Ad4BP/SF-1 regulates cyclic AMP-induced transcription from the proximal promoter (PII) of the human aromatase P450 (CYP19) gene in the ovary.
The Journal of biological chemistry 1995;270(22):13561-6.
1995: Graham-Lorence S; Amarneh B; White R E; Peterson J A; Simpson E R
A three-dimensional model of aromatase cytochrome P450.
Protein science : a publication of the Protein Society 1995;4(6):1065-80.
1995: Amarneh B; Simpson E R
Expression of a recombinant derivative of human aromatase P450 in insect cells utilizing the baculovirus vector system.
Molecular and cellular endocrinology 1995;109(2):R1-5.
1995: Zhao Y; Mendelson C R; Simpson E R
Characterization of the sequences of the human CYP19 (aromatase) gene that mediate regulation by glucocorticoids in adipose stromal cells and fetal hepatocytes.
Molecular endocrinology (Baltimore, Md.) 1995;9(3):340-9.
1995: Nichols J E; Bulun S E; Simpson E R
Effects of conditioned medium from different cultured cell types on aromatase expression in adipose stromal cells.
Journal of the Society for Gynecologic Investigation 1995;2(1):45-50.
1994: Bulun S E; Economos K; Miller D; Simpson E R
CYP19 (aromatase cytochrome P450) gene expression in human malignant endometrial tumors.
The Journal of clinical endocrinology and metabolism 1994;79(6):1831-4.
1994: McAllister J M; Byrd W; Simpson E R
The effects of growth factors and phorbol esters on steroid biosynthesis in isolated human theca interna and granulosa-lutein cells in long term culture.
The Journal of clinical endocrinology and metabolism 1994;79(1):106-12.
1994: Conte F A; Grumbach M M; Ito Y; Fisher C R; Simpson E R
A syndrome of female pseudohermaphrodism, hypergonadotropic hypogonadism, and multicystic ovaries associated with missense mutations in the gene encoding aromatase (P450arom).
The Journal of clinical endocrinology and metabolism 1994;78(6):1287-92.
1994: Simpson E R; Mahendroo M S; Means G D; Kilgore M W; Hinshelwood M M; Graham-Lorence S; Amarneh B; Ito Y; Fisher C R; Michael M D
Aromatase cytochrome P450, the enzyme responsible for estrogen biosynthesis.
Endocrine reviews 1994;15(3):342-55.
1994: Bulun S E; Mahendroo M S; Simpson E R
Aromatase gene expression in adipose tissue: relationship to breast cancer.
The Journal of steroid biochemistry and molecular biology 1994;49(4-6):319-26.
1994: Bulun S E; Simpson E R; Word R A
Expression of the CYP19 gene and its product aromatase cytochrome P450 in human uterine leiomyoma tissues and cells in culture.
The Journal of clinical endocrinology and metabolism 1994;78(3):736-43.
1994: Toda K; Simpson E R; Mendelson C R; Shizuta Y; Kilgore M W
Expression of the gene encoding aromatase cytochrome P450 (CYP19) in fetal tissues.
Molecular endocrinology (Baltimore, Md.) 1994;8(2):210-7.
1994: Bulun S E; Simpson E R
Competitive reverse transcription-polymerase chain reaction analysis indicates that levels of aromatase cytochrome P450 transcripts in adipose tissue of buttocks, thighs, and abdomen of women increase with advancing age.
The Journal of clinical endocrinology and metabolism 1994;78(2):428-32.
1994: Bulun S E; Rosenthal I M; Brodie A M; Inkster S E; Zeller W P; DiGeorge A M; Frasier S D; Kilgore M W; Simpson E R
Use of tissue-specific promoters in the regulation of aromatase cytochrome P450 gene expression in human testicular and ovarian sex cord tumors, as well as in normal fetal and adult gonads.
The Journal of clinical endocrinology and metabolism 1994;78(2):1616-21.
1994: Bulun S E; Simpson E R
Regulation of aromatase expression in human tissues.
Breast cancer research and treatment 1994;30(1):19-29.
1994: Simpson E R; Mahendroo M S; Nichols J E; Bulun S E
Aromatase gene expression in adipose tissue: relationship to breast cancer.
International journal of fertility and menopausal studies 1994;39 Suppl 2():75-83.
1993: Ito Y; Fisher C R; Conte F A; Grumbach M M; Simpson E R
Molecular basis of aromatase deficiency in an adult female with sexual infantilism and polycystic ovaries.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(24):11673-7.
1993: Bulun S E; Rosenthal I M; Brodie A M; Inkster S E; Zeller W P; DiGeorge A M; Frasier S D; Kilgore M W; Simpson E R
Use of tissue-specific promoters in the regulation of aromatase cytochrome P450 gene expression in human testicular and ovarian sex cord tumors, as well as in normal fetal and adult gonads.
The Journal of clinical endocrinology and metabolism 1993;77(6):1616-21.
1993: Amarneh B; Corbin C J; Peterson J A; Simpson E R; Graham-Lorence S
Functional domains of human aromatase cytochrome P450 characterized by linear alignment and site-directed mutagenesis.
Molecular endocrinology (Baltimore, Md.) 1993;7(12):1617-24.
1993: Bulun S E; Price T M; Aitken J; Mahendroo M S; Simpson E R
A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription.
The Journal of clinical endocrinology and metabolism 1993;77(6):1622-8.
1993: Hinshelwood M M; Corbin C J; Tsang P C; Simpson E R
Isolation and characterization of a complementary deoxyribonucleic acid insert encoding bovine aromatase cytochrome P450.
Endocrinology 1993;133(5):1971-7.
1993: Mahendroo M S; Mendelson C R; Simpson E R
Tissue-specific and hormonally controlled alternative promoters regulate aromatase cytochrome P450 gene expression in human adipose tissue.
The Journal of biological chemistry 1993;268(26):19463-70.
1993: Lauber M E; Picton H M; Begeot M; Momoi K; Waterman M R; Simpson E R
Regulation of CYP11A gene expression in bovine ovarian granulosa cells in primary culture by cAMP and phorbol esters is conferred by a common cis-acting element.
Molecular and cellular endocrinology 1993;94(2):235-42.
1993: Lauber M E; Kagawa N; Waterman M R; Simpson E R
cAMP-dependent and tissue-specific expression of genes encoding steroidogenic enzymes in bovine luteal and granulosa cells in primary culture.
Molecular and cellular endocrinology 1993;93(2):227-33.
1993: Bulun S E; Mahendroo M S; Simpson E R
Polymerase chain reaction amplification fails to detect aromatase cytochrome P450 transcripts in normal human endometrium or decidua.
The Journal of clinical endocrinology and metabolism 1993;76(6):1458-63.
1993: Simpson E R; Mahendroo M S; Means G D; Kilgore M W; Corbin C J; Mendelson C R
Tissue-specific promoters regulate aromatase cytochrome P450 expression.
The Journal of steroid biochemistry and molecular biology 1993;44(4-6):321-30.
1993: Demeter-Arlotto M; Rainey W E; Simpson E R
Maintenance and regulation of 17 alpha-hydroxylase expression by bovine thecal cells in primary culture.
Endocrinology 1993;132(3):1353-8.
1993: Simpson E R; Mahendroo M S; Means G D; Kilgore M W; Corbin C J; Mendelson C R
Tissue-specific promoters regulate aromatase cytochrome P450 expression.
Clinical chemistry 1993;39(2):317-24.
1993: Trzeciak W H; LeHoux J G; Waterman M R; Simpson E R
Dexamethasone inhibits corticotropin-induced accumulation of CYP11A and CYP17 messenger RNAs in bovine adrenocortical cells.
Molecular endocrinology (Baltimore, Md.) 1993;7(2):206-13.
1992: Lephart E D; Simpson E R; McPhaul M J; Kilgore M W; Wilson J D; Ojeda S R
Brain aromatase cytochrome P-450 messenger RNA levels and enzyme activity during prenatal and perinatal development in the rat.
Brain research. Molecular brain research 1992;16(3-4):187-92.
1992: Momoi K; Waterman M R; Simpson E R; Zanger U M
3',5'-cyclic adenosine monophosphate-dependent transcription of the CYP11A (cholesterol side chain cleavage cytochrome P450) gene involves a DNA response element containing a putative binding site for transcription factor Sp1.
Molecular endocrinology (Baltimore, Md.) 1992;6(10):1682-90.
1992: Yanase T; Waterman M R; Zachmann M; Winter J S; Simpson E R; Kagimoto M
Molecular basis of apparent isolated 17,20-lyase deficiency: compound heterozygous mutations in the C-terminal region (Arg(496)----Cys, Gln(461)----Stop) actually cause combined 17 alpha-hydroxylase/17,20-lyase deficiency.
Biochimica et biophysica acta 1992;1139(4):275-9.
1992: Lephart E D; Simpson E R; McPhaul M J
Ovarian aromatase cytochrome P-450 mRNA levels correlate with enzyme activity and serum estradiol levels in anestrous, pregnant and lactating rats.
Molecular and cellular endocrinology 1992;85(3):205-14.
1992: Lephart E D; Doody K J; McPhaul M J; Simpson E R
Inverse relationship between ovarian aromatase cytochrome P450 and 5 alpha-reductase enzyme activities and mRNA levels during the estrous cycle in the rat.
The Journal of steroid biochemistry and molecular biology 1992;42(5):439-47.
1992: Imai T; Yanase T; Waterman M R; Simpson E R; Pratt J J
Canadian Mennonites and individuals residing in the Friesland region of The Netherlands share the same molecular basis of 17 alpha-hydroxylase deficiency.
Human genetics 1992;89(1):95-6.
1992: Price T; Aitken J; Simpson E R
Relative expression of aromatase cytochrome P450 in human fetal tissues as determined by competitive polymerase chain reaction amplification.
The Journal of clinical endocrinology and metabolism 1992;74(4):879-83.
1992: Ahlgren R; Yanase T; Simpson E R; Winter J S; Waterman M R
Compound heterozygous mutations (Arg 239----stop, Pro 342----Thr) in the CYP17 (P45017 alpha) gene lead to ambiguous external genitalia in a male patient with partial combined 17 alpha-hydroxylase/17,20-lyase deficiency.
The Journal of clinical endocrinology and metabolism 1992;74(3):667-72.
1992: Kilgore M W; Means G D; Mendelson C R; Simpson E R
Alternative promotion of aromatase P-450 expression in the human placenta.
Molecular and cellular endocrinology 1992;83(1):R9-16.
1991: Sanghera M K; Simpson E R; McPhaul M J; Kozlowski G; Conley A J; Lephart E D
Immunocytochemical distribution of aromatase cytochrome P450 in the rat brain using peptide-generated polyclonal antibodies.
Endocrinology 1991;129(6):2834-44.
1991: Means G D; Kilgore M W; Mahendroo M S; Mendelson C R; Simpson E R
Tissue-specific promoters regulate aromatase cytochrome P450 gene expression in human ovary and fetal tissues.
Molecular endocrinology (Baltimore, Md.) 1991;5(12):2005-13.
1991: Biason A; Mantero F; Scaroni C; Simpson E R; Waterman M R
Deletion within the CYP17 gene together with insertion of foreign DNA is the cause of combined complete 17 alpha-hydroxylase/17,20-lyase deficiency in an Italian patient.
Molecular endocrinology (Baltimore, Md.) 1991;5(12):2037-45.
1991: Graham-Lorence S; Khalil M W; Lorence M C; Mendelson C R; Simpson E R
Structure-function relationships of human aromatase cytochrome P-450 using molecular modeling and site-directed mutagenesis.
The Journal of biological chemistry 1991;266(18):11939-46.
1991: Mahendroo M S; Means G D; Mendelson C R; Simpson E R
Tissue-specific expression of human P-450AROM. The promoter responsible for expression in adipose tissue is different from that utilized in placenta.
The Journal of biological chemistry 1991;266(17):11276-81.
1991: Lauber M E; Bengtson T; Waterman M R; Simpson E R
Regulation of CYP11A (P450SCC) and CYP17 (P450(17) alpha) gene expression in bovine luteal cells in primary culture.
The Journal of biological chemistry 1991;266(17):11170-5.
1991: Zanger U M; Lund J; Simpson E R; Waterman M R
Activation of transcription in cell-free extracts by a novel cAMP-responsive sequence from the bovine CYP17 gene.
The Journal of biological chemistry 1991;266(18):11417-20.
1991: Lephart E D; Simpson E R; Trzeciak W H
Rat adrenal 5 alpha-reductase mRNA content and enzyme activity are sex hormone dependent.
Journal of molecular endocrinology 1991;6(2):163-70.
1991: Doody K J; Lephart E D; Stirling D; Lorence M C; Magness R R; McPhaul M J; Simpson E R
Expression of mRNA species encoding steroidogenic enzymes in the rat ovary.
Journal of molecular endocrinology 1991;6(2):153-62.
1991: Yanase T; Simpson E R; Waterman M R
17 alpha-hydroxylase/17,20-lyase deficiency: from clinical investigation to molecular definition.
Endocrine reviews 1991;12(1):91-108.
1991: Stirling D; Waterman M R; Simpson E R
Expression of mRNA encoding basic fibroblast growth factor (bFGF) in bovine corpora lutea and cultured luteal cells.
Journal of reproduction and fertility 1991;91(1):1-8.
1991: Lauber M E; Waterman M R; Simpson E R
Expression of genes encoding steroidogenic enzymes in the bovine corpus luteum.
Journal of reproduction and fertility. Supplement 1991;43():57-64.
1990: Lephart E D; Andersson S; Simpson E R
Expression of neural 5 alpha-reductase messenger ribonucleic acid: comparison to 5 alpha-reductase activity during prenatal development in the rat.
Endocrinology 1990;127(3):1121-8.
1990: McAllister J M; Mason J I; Byrd W; Trant J M; Waterman M R; Simpson E R
Proliferating human granulosa-lutein cells in long term monolayer culture: expression of aromatase, cholesterol side-chain cleavage, and 3 beta-hydroxysteroid dehydrogenase.
The Journal of clinical endocrinology and metabolism 1990;71(1):26-33.
1990: Yanase T; Sanders D; Shibata A; Matsui N; Simpson E R; Waterman M R
Combined 17 alpha-hydroxylase/17,20-lyase deficiency due to a 7-basepair duplication in the N-terminal region of the cytochrome P45017 alpha (CYP17) gene.
The Journal of clinical endocrinology and metabolism 1990;70(5):1325-9.
1990: Doody K J; Lorence M C; Mason J I; Simpson E R
Expression of messenger ribonucleic acid species encoding steroidogenic enzymes in human follicles and corpora lutea throughout the menstrual cycle.
The Journal of clinical endocrinology and metabolism 1990;70(4):1041-5.
1990: Simpson E R; Lund J; Ahlgren R; Waterman M R
Regulation by cyclic AMP of the genes encoding steroidogenic enzymes: when the light finally shines...
Molecular and cellular endocrinology 1990;70(2):C25-8.
1990: Waterman M R; Lund J; Ahlgren R; Wu D; Simpson E R
Regulation of steroid hydroxylase gene expression and steroid hormone biosynthesis.
Biochemical Society transactions 1990;18(1):26-8.
1990: Ahlgren R; Simpson E R; Waterman M R; Lund J
Characterization of the promoter/regulatory region of the bovine CYP11A (P-450scc) gene. Basal and cAMP-dependent expression.
The Journal of biological chemistry 1990;265(6):3313-9.
1990: Lund J; Ahlgren R; Wu D H; Kagimoto M; Simpson E R; Waterman M R
Transcriptional regulation of the bovine CYP17 (P-450(17)alpha) gene. Identification of two cAMP regulatory regions lacking the consensus cAMP-responsive element (CRE).
The Journal of biological chemistry 1990;265(6):3304-12.
1990: Stirling D; Magness R R; Stone R; Waterman M R; Simpson E R
Angiotensin II inhibits luteinizing hormone-stimulated cholesterol side chain cleavage expression and stimulates basic fibroblast growth factor expression in bovine luteal cells in primary culture.
The Journal of biological chemistry 1990;265(1):5-8.
1990: Mendelson C R; Means G D; Mahendroo M S; Corbin C J; Steinkampf M P; Graham-Lorence S; Simpson E R
Use of molecular probes to study regulation of aromatase cytochrome P-450.
Biology of reproduction 1990;42(1):1-10.
1990: Waterman M R; Simpson E R
Steroidogenic capacity in the adrenal cortex and its regulation.
Progress in drug research. Fortschritte der Arzneimittelforschung. Progrès des recherches pharmaceutiques 1990;34():359-81.
1990: Simpson E R; Price T; Aitken J; Mahendroo M; Means G; Kilgore M
The aromatase enzyme: from cloning to cancer.
Princess Takamatsu symposia 1990;21():75-87.
1989: Means G D; Mahendroo M S; Corbin C J; Mathis J M; Powell F E; Mendelson C R; Simpson E R
Structural analysis of the gene encoding human aromatase cytochrome P-450, the enzyme responsible for estrogen biosynthesis.
The Journal of biological chemistry 1989;264(32):19385-91.
1989: Yanase T; Kagimoto M; Suzuki S; Hashiba K; Simpson E R; Waterman M R
Deletion of a phenylalanine in the N-terminal region of human cytochrome P-450(17 alpha) results in partial combined 17 alpha-hydroxylase/17,20-lyase deficiency.
The Journal of biological chemistry 1989;264(30):18076-82.
1989: McAllister J M; Kerin J F; Trant J M; Estabrook R W; Mason J I; Waterman M R; Simpson E R
Regulation of cholesterol side-chain cleavage and 17 alpha-hydroxylase/lyase activities in proliferating human theca interna cells in long term monolayer culture.
Endocrinology 1989;125(4):1959-66.
1989: Kagimoto K; Waterman M R; Kagimoto M; Ferreira P; Simpson E R; Winter J S
Identification of a common molecular basis for combined 17 alpha-hydroxylase/17,20-lyase deficiency in two Mennonite families.
Human genetics 1989;82(3):285-6.
1989: Bhasker C R; Adler B S; Dee A; John M E; Kagimoto M; Zuber M X; Ahlgren R; Wang X D; Simpson E R; Waterman M R
Structural characterization of the bovine CYP17 (17 alpha-hydroxylase) gene.
Archives of biochemistry and biophysics 1989;271(2):479-87.
1989: Simpson E R; Merrill J C; Hollub A J; Graham-Lorence S; Mendelson C R
Regulation of estrogen biosynthesis by human adipose cells.
Endocrine reviews 1989;10(2):136-48.
1989: Boggaram V; John M E; Simpson E R; Waterman M R
Effect of ACTH on the stability of mRNAs encoding bovine adrenocortical P-450scc, P-45011 beta, P-45017 alpha, P-450C21 and adrenodoxin.
Biochemical and biophysical research communications 1989;160(3):1227-32.
1989: Mathis J M; Houser W H; Bresnick E; Cidlowski J A; Hines R N; Prough R A; Simpson E R
Glucocorticoid regulation of the rat cytochrome P450c (P450IA1) gene: receptor binding within intron I.
Archives of biochemistry and biophysics 1989;269(1):93-105.
1989: Lund J; Mason J I; Simpson E R; Waterman M R
Developmental regulation of P-45017 alpha gene expression in fetal bovine adrenal.
Endocrine research 1989;15(1-2):17-29.
1989: Waterman M R; Mason J I; Zuber M X; Lorence M C; Clark B J; Trant J M; Barnes H J; Simpson E R; Estabrook R W
Expression of P-450 enzyme activities in heterologous cells by transfection.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1989;13():155-63.
1988: Corbin C J; Graham-Lorence S; McPhaul M; Mason J I; Mendelson C R; Simpson E R
Isolation of a full-length cDNA insert encoding human aromatase system cytochrome P-450 and its expression in nonsteroidogenic cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):8948-52.
1988: McPhaul M J; Noble J F; Simpson E R; Mendelson C R; Wilson J D
The expression of a functional cDNA encoding the chicken cytochrome P-450arom (aromatase) that catalyzes the formation of estrogen from androgen.
The Journal of biological chemistry 1988;263(31):16358-63.
1988: Yanase T; Kagimoto M; Matsui N; Simpson E R; Waterman M R
Combined 17 alpha-hydroxylase/17,20-lyase deficiency due to a stop codon in the N-terminal region of 17 alpha-hydroxylase cytochrome P-450.
Molecular and cellular endocrinology 1988;59(3):249-53.
1988: Steinkampf M P; Mendelson C R; Simpson E R
Effects of epidermal growth factor and insulin-like growth factor I on the levels of mRNA encoding aromatase cytochrome P-450 of human ovarian granulosa cells.
Molecular and cellular endocrinology 1988;59(1-2):93-9.
1988: Rodgers R J; Waterman M R; Simpson E R; Magness R R
Immunoblot analysis of cholesterol side-chain cleavage cytochrome P-450 and adrenodoxin in corpora lutea of cyclic and late-pregnant sheep.
Journal of reproduction and fertility 1988;83(2):843-50.
1988: Rodgers R J; Mitchell M D; Simpson E R
Secretion of progesterone and prostaglandins by cells of bovine corpora lutea from three stages of the luteal phase.
The Journal of endocrinology 1988;118(1):121-6.
1988: Kagimoto M; Winter J S; Kagimoto K; Simpson E R; Waterman M R
Structural characterization of normal and mutant human steroid 17 alpha-hydroxylase genes: molecular basis of one example of combined 17 alpha-hydroxylase/17,20 lyase deficiency.
Molecular endocrinology (Baltimore, Md.) 1988;2(6):564-70.
1988: Kagimoto M; Kagimoto K; Simpson E R; Waterman M R
Transcription of the bovine adrenodoxin gene produces two species of mRNA of which only one is translated into adrenodoxin.
The Journal of biological chemistry 1988;263(18):8925-8.
1988: Zuber M X; Mason J I; Simpson E R; Waterman M R
Simultaneous transfection of COS-1 cells with mitochondrial and microsomal steroid hydroxylases: incorporation of a steroidogenic pathway into nonsteroidogenic cells.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(3):699-703.
1988: Waterman M R; Mason J I; Simpson E R
Regulation of steroid hydroxylase gene expression.
Progress in clinical and biological research 1988;274():543-55.
1988: Simpson E R; Waterman M R
Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH.
Annual review of physiology 1988;50():427-40.
1987: Trzeciak W H; Duda T; Waterman M R; Simpson E R
Tetradecanoyl phorbol acetate suppresses follicle-stimulating hormone-induced synthesis of the cholesterol side-chain cleavage enzyme complex in rat ovarian granulosa cells.
The Journal of biological chemistry 1987;262(31):15246-50.
1987: Simpson E R; Evans C T; Corbin C J; Powell F E; Ledesma D B; Mendelson C R
Sequencing of cDNA inserts encoding aromatase cytochrome P-450 (P-450AROM).
Molecular and cellular endocrinology 1987;52(3):267-72.
1987: Mendelson C R; Simpson E R
Regulation of estrogen biosynthesis by human adipose cells in vitro.
Molecular and cellular endocrinology 1987;52(3):169-76.
1987: Trzeciak W H; Duda T; Waterman M R; Simpson E R
Effects of epidermal growth factor on the synthesis of the cholesterol side-chain cleavage enzyme complex in rat ovarian granulosa cells in primary culture.
Molecular and cellular endocrinology 1987;52(1-2):43-50.
1987: Steinkampf M P; Mendelson C R; Simpson E R
Regulation by follicle-stimulating hormone of the synthesis of aromatase cytochrome P-450 in human granulosa cells.
Molecular endocrinology (Baltimore, Md.) 1987;1(7):465-71.
1987: Mendelson C R; Merrill J C; Steinkampf M P; Simpson E R
Regulation of the synthesis of aromatase cytochrome P-450 in human adipose stromal and ovarian granulosa cells.
Steroids 1987;50(1-3):51-9.
1987: Simpson E R; Evans C T; Mendelson C R
Aromatase cytochrome P-450: preparation of polyclonal and monoclonal antibodies and a cDNA insert.
Steroids 1987;50(1-3):3-9.
1987: Bradshaw K D; Waterman M R; Couch R T; Simpson E R; Zuber M X
Characterization of complementary deoxyribonucleic acid for human adrenocortical 17 alpha-hydroxylase: a probe for analysis of 17 alpha-hydroxylase deficiency.
Molecular endocrinology (Baltimore, Md.) 1987;1(5):348-54.
1987: Evans C T; Corbin C J; Saunders C T; Merrill J C; Simpson E R; Mendelson C R
Regulation of estrogen biosynthesis in human adipose stromal cells. Effects of dibutyryl cyclic AMP, epidermal growth factor, and phorbol esters on the synthesis of aromatase cytochrome P-450.
The Journal of biological chemistry 1987;262(14):6914-20.
1987: Rodgers R J; Waterman M R; Simpson E R
Levels of messenger ribonucleic acid encoding cholesterol side-chain cleavage cytochrome P-450, 17 alpha-hydroxylase cytochrome P-450, adrenodoxin, and low density lipoprotein receptor in bovine follicles and corpora lutea throughout the ovarian cycle.
Molecular endocrinology (Baltimore, Md.) 1987;1(3):274-9.
1987: Rodgers R J; Mason J I; Waterman M R; Simpson E R
Regulation of the synthesis of 3-hydroxy-3-methylglutaryl coenzyme A reductase in the bovine ovary in vivo and in vitro.
Molecular endocrinology (Baltimore, Md.) 1987;1(2):172-80.
1987: Simpson E R; Mason J I; John M E; Zuber M X; Rodgers R J; Waterman M R
Regulation of the biosynthesis of steroidogenic enzymes.
Journal of steroid biochemistry 1987;27(4-6):801-5.
1987: Mendelson C R; Evans C T; Simpson E R
Regulation of aromatase in estrogen-producing cells.
Journal of steroid biochemistry 1987;27(4-6):753-7.
1986: Evans C T; Ledesma D B; Schulz T Z; Simpson E R; Mendelson C R
Isolation and characterization of a complementary DNA specific for human aromatase-system cytochrome P-450 mRNA.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(17):6387-91.
1986: John M E; John M C; Boggaram V; Simpson E R; Waterman M R
Transcriptional regulation of steroid hydroxylase genes by corticotropin.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(13):4715-9.
1986: John M E; Okamura T; Dee A; Adler B; John M C; White P C; Simpson E R; Waterman M R
Bovine steroid 21-hydroxylase: regulation of biosynthesis.
Biochemistry 1986;25(10):2846-53.
1986: Mathis J M; Prough R A; Hines R N; Bresnick E; Simpson E R
Regulation of cytochrome P-450c by glucocorticoids and polycyclic aromatic hydrocarbons in cultured fetal rat hepatocytes.
Archives of biochemistry and biophysics 1986;246(1):439-48.
1986: Zuber M X; John M E; Okamura T; Simpson E R; Waterman M R
Bovine adrenocortical cytochrome P-450(17 alpha). Regulation of gene expression by ACTH and elucidation of primary sequence.
The Journal of biological chemistry 1986;261(5):2475-82.
1986: Waterman M R; Mason J I; Zuber M X; John M E; Rodgers R J; Simpson E R
Control of gene expression of adrenal steroid hydroxylases and related enzymes.
Endocrine research 1986;12(4):393-408.
1985: Okamura T; John M E; Zuber M X; Simpson E R; Waterman M R
Molecular cloning and amino acid sequence of the precursor form of bovine adrenodoxin: evidence for a previously unidentified COOH-terminal peptide.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(17):5705-9.
1985: John M E; John M C; Simpson E R; Waterman M R
Regulation of cytochrome P-45011 beta gene expression by adrenocorticotropin.
The Journal of biological chemistry 1985;260(9):5760-7.
1984: John M E; John M C; Ashley P; MacDonald R J; Simpson E R; Waterman M R
Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(18):5628-32.
1984: John M E; Simpson E R; Boggaram V; Waterman M R
Molecular cloning of steroid hydroxylases.
Endocrine research 1984;10(3-4):319-33.

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