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Gennady Bocharov

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Burkhard Ludewig; James Sharpe; Jens V Stein; Volker Thiel; Luisa Cervantes-Barragan; Gennady Bocharov
A global "imaging'' view on systems approaches in immunology.
H T Banks; Gennady Bocharov; Marie Doumic; Sandra Giest; Cristina Peligero; Tim Schenkel; Karyn L Sutton; W Clayton Thompson; Jordi Argilaguet; Andreas Meyerhans
A new model for the estimation of cell proliferation dynamics using CFSE data.
Gennady Bocharov; VA Chereshnev; A A Danilov; G I Marchuk; Yu V Vassilevski; Burkhard Ludewig
Simulation of the interferon-mediated protective field in lymphoid organs with their spatial and functional organization taken into consideration.

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All Publications

2012: Burkhard Ludewig; James Sharpe; Jens V Stein; Volker Thiel; Luisa Cervantes-Barragan; Gennady Bocharov
A global "imaging'' view on systems approaches in immunology.
European journal of immunology 2012;42(12):3116-25.
2011: H T Banks; Gennady Bocharov; Marie Doumic; Sandra Giest; Cristina Peligero; Tim Schenkel; Karyn L Sutton; W Clayton Thompson; Jordi Argilaguet; Andreas Meyerhans
A new model for the estimation of cell proliferation dynamics using CFSE data.
Journal of immunological methods 2011;373(1-2):143-60.
2011: Gennady Bocharov; VA Chereshnev; A A Danilov; G I Marchuk; Yu V Vassilevski; Burkhard Ludewig
Simulation of the interferon-mediated protective field in lymphoid organs with their spatial and functional organization taken into consideration.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections / translated from Russian 2011;439():194-6.
2011: Gennady Bocharov; Juan Quiel; Tatyana Luzyanina; Hagit Alon; Egor Chiglintsev; Valery Chereshnev; Martin Meier-Schellersheim; William E Paul; Zvi Grossman
Feedback regulation of proliferation vs. differentiation rates explains the dependence of CD4 T-cell expansion on precursor number.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(8):3318-23.
2011: Juan Quiel; Stephane Caucheteux; Arian Dominic John laurence; Nevil J Singh; Gennady Bocharov; Shlomo Z Ben-Sasson; Zvi Grossman; William E Paul
Antigen-stimulated CD4 T-cell expansion is inversely and log-linearly related to precursor number.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(8):3312-7.
2011: Javier P Martínez; Gennady Bocharov; Anna Ignatovich; Jochen Reiter; Matthias T Dittmar; Simon Wain-Hobson; Andreas Meyerhans
Fitness ranking of individual mutants drives patterns of epistatic interactions in HIV-1.
PloS one 2011;6(3):e18375.
2010: Gennady Bocharov; Roland Züst; Luisa Cervantes-Barragan; Tatyana Luzyanina; Egor Chiglintsev; VA Chereshnev; Volker Thiel; Burkhard Ludewig
A systems immunology approach to plasmacytoid dendritic cell function in cytopathic virus infections.
PLoS pathogens 2010;6(7):e1001017.
2009: Tatyana Luzyanina; Dirk Roose; Gennady Bocharov
Distributed parameter identification for a label-structured cell population dynamics model using CFSE histogram time-series data.
Journal of mathematical biology 2009;59(5):581-603.
2007: Urban Sester; Martina Sester; Hans Köhler; Hans W Pees; Barbara C Gärtner; Simon Wain-Hobson; Gennady Bocharov; Andreas Meyerhans
Maintenance of HIV-specific central and effector memory CD4 and CD8 T cells requires antigen persistence.
AIDS research and human retroviruses 2007;23(4):549-53.
2007: Tatyana Luzyanina; Dirk Roose; Tim Schenkel; Martina Sester; Stephan Ehl; Andreas Meyerhans; Gennady Bocharov
Numerical modelling of label-structured cell population growth using CFSE distribution data.
Theoretical biology & medical modelling 2007;4():26.
2007: Tatyana Luzyanina; Sonja Mrusek; John T Edwards; Dirk Roose; Stephan Ehl; Gennady Bocharov
Computational analysis of CFSE proliferation assay.
Journal of mathematical biology 2007;54(1):57-89.
2005: Gennady Bocharov; Neville J Ford; John Edwards; Tanja Breinig; Simon Wain-Hobson; Andreas Meyerhans
A genetic-algorithm approach to simulating human immunodeficiency virus evolution reveals the strong impact of multiply infected cells and recombination.
The Journal of general virology 2005;86(Pt 11):3109-18.
2005: Gennady Bocharov; Neville J Ford; Burkhard Ludewig
A mathematical approach for optimizing dendritic cell-based immunotherapy.
Methods in molecular medicine 2005;109():19-34.
2004: Burkhard Ludewig; Philippe Krebs; Tobias Junt; Helen Metters; Neville J Ford; Roy M Anderson; Gennady Bocharov
Determining control parameters for dendritic cell-cytotoxic T lymphocyte interaction.
European journal of immunology 2004;34(9):2407-18.
2004: Gennady Bocharov; Burkhard Ludewig; Antonio Bertoletti; Paul Klenerman; Tobias Junt; Philippe Krebs; Tatyana Luzyanina; Cristophe Fraser; Roy M Anderson
Underwhelming the immune response: effect of slow virus growth on CD8+-T-lymphocyte responses.
Journal of virology 2004;78(5):2247-54.
2003: Andreas Meyerhans; Andreas Jung; Reinhard Maier; Jean-Pierre Vartanian; Gennady Bocharov; Simon Wain-Hobson
The non-clonal and transitory nature of HIV in vivo.
Swiss medical weekly 2003;133(33-34):451-4.
2003: Gennady Bocharov; Paul Klenerman; Stephan Ehl
Modelling the dynamics of LCMV infection in mice: II. Compartmental structure and immunopathology.
Journal of theoretical biology 2003;221(3):349-78.
2003: Burkhard Ludewig; Philippe Krebs; Tobias Junt; Gennady Bocharov
Dendritic cell homeostasis in the regulation of self-reactivity.
Current pharmaceutical design 2003;9(3):221-31.
2002: Andreas Jung; Reinhard Maier; Jean-Pierre Vartanian; Gennady Bocharov; Volker Jung; Ulrike Fischer; Eckart Meese; Simon Wain-Hobson; Andreas Meyerhans
Recombination: Multiply infected spleen cells in HIV patients.
Nature 2002;418(6894):144.
2001: Tatyana Luzyanina; K Engelborghs; Stephan Ehl; Paul Klenerman; Gennady Bocharov
Low level viral persistence after infection with LCMV: a quantitative insight through numerical bifurcation analysis.
Mathematical biosciences 2001;173(1):1-23.
2001: Gennady Bocharov; Paul Klenerman; Stephan Ehl
Predicting the dynamics of antiviral cytotoxic T-cell memory in response to different stimuli: cell population structure and protective function.
Immunology and cell biology 2001;79(1):74-86.
2000: W Barchet; Stephan Oehen; Paul Klenerman; Dominik Wodarz; Gennady Bocharov; Alun L Lloyd; Martin A Nowak; Hans Hengartner; Rolf M Zinkernagel; Stephan Ehl
Direct quantitation of rapid elimination of viral antigen-positive lymphocytes by antiviral CD8(+) T cells in vivo.
European journal of immunology 2000;30(5):1356-63.
1998: Stephan Ehl; Paul Klenerman; Rolf M Zinkernagel; Gennady Bocharov
The impact of variation in the number of CD8(+) T-cell precursors on the outcome of virus infection.
Cellular immunology 1998;189(1):67-73.
1998: Gennady Bocharov
Modelling the dynamics of LCMV infection in mice: conventional and exhaustive CTL responses.
Journal of theoretical biology 1998;192(3):283-308.