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Robert Simpson
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Research Profile (preview)
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Network (preview)
10
Kladde, MP
5
Xu, M
3
Weiss, K
2
Workman, Jerry
2
Ducker, Charles
1
Angerer, Lynne
1
Koshland, Douglas
1
Ma, Hong
1
Peterson, Craig
1
Van Etten, James
1
Landsman, David
1
Angerer, Robert
1
Surcel, Alexandra
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Publications
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All Publications
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2008: Surcel Alexandra; Koshland Douglas; Ma Hong; Simpson Robert T
Cohesin interaction with centromeric minichromosomes shows a multi-complex rod-shaped structure.
PloS one 2008;3(6):e2453.
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2005: Ruan Chun; Workman Jerry L; Simpson Robert T
The DNA repair protein yKu80 regulates the function of recombination enhancer during yeast mating type switching.
Molecular and cellular biology 2005;25(19):8476-85.
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2005: Ercan Sevinc; Reese Joseph C; Workman Jerry L; Simpson Robert T
Yeast recombination enhancer is stimulated by transcription activation.
Molecular and cellular biology 2005;25(18):7976-87.
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2004: Ercan Sevinc; Simpson Robert T
Global chromatin structure of 45,000 base pairs of chromosome III in a- and alpha-cell yeast and during mating-type switching.
Molecular and cellular biology 2004;24(22):10026-35.
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2004: Simpson Robert T; Ducker Charles E; Diller John D; Ruan Chun
Purification of native, defined chromatin segments.
Methods in enzymology 2004;375():158-70.
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2001: Wang X; Simpson R T
Chromatin structure mapping in Saccharomyces cerevisiae in vivo with DNase I.
Nucleic acids research 2001;29(9):1943-50.
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2000: Gavin I M; Kladde M P; Simpson R T
Tup1p represses Mcm1p transcriptional activation and chromatin remodeling of an a-cell-specific gene.
The EMBO journal 2000;19(21):5875-83.
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2000: Ducker C E; Simpson R T
The organized chromatin domain of the repressed yeast a cell-specific gene STE6 contains two molecules of the corepressor Tup1p per nucleosome.
The EMBO journal 2000;19(3):400-9.
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1999: Ravindra A; Weiss K; Simpson R T
High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating-type locus HMRa.
Molecular and cellular biology 1999;19(12):7944-50.
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1999: Simpson R T
In vivo methods to analyze chromatin structure.
Current opinion in genetics & development 1999;9(2):225-9.
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1999: Kladde M P; Xu M; Simpson R T
DNA methyltransferases as probes for chromatin structure in yeast.
Methods in molecular biology (Clifton, N.J.) 1999;119():395-416.
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1999: Kladde M P; Xu M; Simpson R T
DNA methyltransferases as probes of chromatin structure in vivo.
Methods in enzymology 1999;304():431-47.
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1998: Weiss K; Simpson R T
High-resolution structural analysis of chromatin at specific loci: Saccharomyces cerevisiae silent mating type locus HMLalpha.
Molecular and cellular biology 1998;18(9):5392-403.
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1998: Xu M; Kladde M P; Van Etten J L; Simpson R T
Cloning, characterization and expression of the gene coding for a cytosine-5-DNA methyltransferase recognizing GpC.
Nucleic acids research 1998;26(17):3961-6.
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1998: Simpson R T
Chromatin structure and analysis of mechanisms of activators and repressors.
Methods (San Diego, Calif.) 1998;15(4):283-94.
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1998: Patterton H G; Landel C C; Landsman D; Peterson C L; Simpson R T
The biochemical and phenotypic characterization of Hho1p, the putative linker histone H1 of Saccharomyces cerevisiae.
The Journal of biological chemistry 1998;273(13):7268-76.
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1998: Xu M; Simpson R T; Kladde M P
Gal4p-mediated chromatin remodeling depends on binding site position in nucleosomes but does not require DNA replication.
Molecular and cellular biology 1998;18(3):1201-12.
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1998: Kladde M P; Simpson R T
Rapid detection of functional expression of C-5-DNA methyltransferases in yeast.
Nucleic acids research 1998;26(5):1354-5.
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1997: Gavin I M; Simpson R T
Interplay of yeast global transcriptional regulators Ssn6p-Tup1p and Swi-Snf and their effect on chromatin structure.
The EMBO journal 1997;16(20):6263-71.
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1997: Weiss K; Simpson R T
Cell type-specific chromatin organization of the region that governs directionality of yeast mating type switching.
The EMBO journal 1997;16(14):4352-60.
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1996: Kladde M P; Xu M; Simpson R T
Direct study of DNA-protein interactions in repressed and active chromatin in living cells.
The EMBO journal 1996;15(22):6290-300.
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1996: Kladde M P; Simpson R T
Chromatin structure mapping in vivo using methyltransferases.
Methods in enzymology 1996;274():214-33.
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1995: Patterton H G; Simpson R T
Modified curved DNA that could allow local DNA underwinding at the nucleosomal pseudodyad fails to position a nucleosome in vivo.
Nucleic acids research 1995;23(20):4170-9.
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1994: Patterton H G; Simpson R T
Nucleosomal location of the STE6 TATA box and Mat alpha 2p-mediated repression.
Molecular and cellular biology 1994;14(6):4002-10.
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1994: Cooper J P; Roth S Y; Simpson R T
The global transcriptional regulators, SSN6 and TUP1, play distinct roles in the establishment of a repressive chromatin structure.
Genes & development 1994;8(12):1400-10.
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1994: Kladde M P; Simpson R T
Positioned nucleosomes inhibit Dam methylation in vivo.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(4):1361-5.
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1993: Murphy M R; Shimizu M; Roth S Y; Dranginis A M; Simpson R T
DNA-protein interactions at the S.cerevisiae alpha 2 operator in vivo.
Nucleic acids research 1993;21(14):3295-300.
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1993: Simpson R T; Roth S Y; Morse R H; Patterton H G; Cooper J P; Murphy M; Kladde M P; Shimizu M
Nucleosome positioning and transcription.
Cold Spring Harbor symposia on quantitative biology 1993;58():237-45.
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1992: Morse R H; Roth S Y; Simpson R T
A transcriptionally active tRNA gene interferes with nucleosome positioning in vivo.
Molecular and cellular biology 1992;12(9):4015-25.
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1992: Roth S Y; Shimizu M; Johnson L; Grunstein M; Simpson R T
Stable nucleosome positioning and complete repression by the yeast alpha 2 repressor are disrupted by amino-terminal mutations in histone H4.
Genes & development 1992;6(3):411-25.
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1991: Shimizu M; Roth S Y; Szent-Gyorgyi C; Simpson R T
Nucleosomes are positioned with base pair precision adjacent to the alpha 2 operator in Saccharomyces cerevisiae.
The EMBO journal 1991;10(10):3033-41.
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1991: Simpson R T
Nucleosome positioning: occurrence, mechanisms, and functional consequences.
Progress in nucleic acid research and molecular biology 1991;40():143-84.
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1991: Roth S Y; Simpson R T
Yeast minichromosomes.
Methods in cell biology 1991;35():289-314.
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1990: Roth S Y; Dean A; Simpson R T
Yeast alpha 2 repressor positions nucleosomes in TRP1/ARS1 chromatin.
Molecular and cellular biology 1990;10(5):2247-60.
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1990: Simpson R T
Nucleosome positioning can affect the function of a cis-acting DNA element in vivo.
Nature 1990;343(6256):387-9.
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1989: Dean A; Pederson D S; Simpson R T
Isolation of yeast plasmid chromatin.
Methods in enzymology 1989;170():26-41.
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1988: Morse R H; Simpson R T
DNA in the nucleosome.
Cell 1988;54(3):285-7.
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1988: Angerer L M; Chambers S A; Yang Q; Venkatesan M; Angerer R C; Simpson R T
Expression of a collagen gene in mesenchyme lineages of the Strongylocentrotus purpuratus embryo.
Genes & development 1988;2(2):239-46.
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1987: Morse R H; Pederson D S; Dean A; Simpson R T
Yeast nucleosomes allow thermal untwisting of DNA.
Nucleic acids research 1987;15(24):10311-30.
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1986: Pederson D S; Venkatesan M; Thoma F; Simpson R T
Isolation of an episomal yeast gene and replication origin as chromatin.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(19):7206-10.
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1986: Venkatesan M; Simpson R T
Isolation and characterization of spicule proteins from Strongylocentrotus purpuratus.
Experimental cell research 1986;166(1):259-64.
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1986: Venkatesan M; de Pablo F; Vogeli G; Simpson R T
Structure and developmentally regulated expression of a Strongylocentrotus purpuratus collagen gene.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(10):3351-5.
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1986: Pederson D S; Thoma F; Simpson R T
Core particle, fiber, and transcriptionally active chromatin structure.
Annual review of cell biology 1986;2():117-47.
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1985: FitzGerald P C; Simpson R T
Effects of sequence alterations in a DNA segment containing the 5 S RNA gene from Lytechinus variegatus on positioning of a nucleosome core particle in vitro.
The Journal of biological chemistry 1985;260(28):15318-24.
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1985: Simpson R T; Thoma F; Brubaker J M
Chromatin reconstituted from tandemly repeated cloned DNA fragments and core histones: a model system for study of higher order structure.
Cell 1985;42(3):799-808.
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1985: Clarke M F; FitzGerald P C; Brubaker J M; Simpson R T
Sequence-specific interaction of histones with the simian virus 40 enhancer region in vitro.
The Journal of biological chemistry 1985;260(23):12394-7.
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1985: Thoma F; Simpson R T
Local protein-DNA interactions may determine nucleosome positions on yeast plasmids.
Nature 1985;315(6016):250-2.
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1984: Thoma F; Bergman L W; Simpson R T
Nuclease digestion of circular TRP1ARS1 chromatin reveals positioned nucleosomes separated by nuclease-sensitive regions.
Journal of molecular biology 1984;177(4):715-33.
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1980: Simpson R T; Bergman L W
Structure of sea urchin sperm chromatin core particle.
The Journal of biological chemistry 1980;255(22):10702-9.
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