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Charles Sing

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Pathik D Wadhwa; Roger Smith; Claudia Buss; Sonja Entringer; Naveed Farhana; James E Hixson; Calvin J Hobel; Lawrence Shimmin; Hyagriv N Simhan; Charles F Sing
Variation in the maternal corticotrophin releasing hormone-binding protein (CRH-BP) gene and birth weight in Blacks, Hispanics and Whites.
Li Ma; Charles F Sing; Eric Boerwinkle; Ariel Brautbar; Andrew G Clark; Alon Keinan
Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations.
Benjamin Koester; Thomas J Rea; Alexander S Szalay; Alan R Templeton; Charles F Sing
Long-range autocorrelations of CpG islands in the human genome.

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2012: Pathik D Wadhwa; Roger Smith; Claudia Buss; Sonja Entringer; Naveed Farhana; James E Hixson; Calvin J Hobel; Lawrence Shimmin; Hyagriv N Simhan; Charles F Sing
Variation in the maternal corticotrophin releasing hormone-binding protein (CRH-BP) gene and birth weight in Blacks, Hispanics and Whites.
PloS one 2012;7(9):e43931.
2012: Li Ma; Charles F Sing; Eric Boerwinkle; Ariel Brautbar; Andrew G Clark; Alon Keinan
Knowledge-driven analysis identifies a gene-gene interaction affecting high-density lipoprotein cholesterol levels in multi-ethnic populations.
PLoS genetics 2012;8(5):e1002714.
2012: Benjamin Koester; Thomas J Rea; Alexander S Szalay; Alan R Templeton; Charles F Sing
Long-range autocorrelations of CpG islands in the human genome.
PloS one 2012;7(1):e29889.
2010: Vinod K Misra; Calvin J Hobel; Charles F Sing
The effects of maternal weight gain patterns on term birth weight in African-American women.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2010;23(8):842-9.
2010: David Sing; Charles F Sing
Impact of direct soil exposures from airborne dust and geophagy on human health.
International journal of environmental research and public health 2010;7(3):1205-23.
2010: Jari H Stengård; Greg Dyson; Ruth Frikke-Schmidt; Anne Tybjaerg-Hansen; Borge G Nordestgaard; Charles F Sing
Context-dependent associations between variation in risk of ischemic heart disease and variation in the 5' promoter region of the apolipoprotein E gene in Danish women.
Circulation. Cardiovascular genetics 2010;3(1):22-30.
2009: Vinod K Misra; Calvin J Hobel; Charles F Sing
Placental blood flow and the risk of preterm delivery.
Placenta 2009;30(7):619-24.
2009: Gregory E Dyson; Ruth Frikke-Schmidt; Børge G Nordestgaard; Anne Tybjaerg-Hansen; Charles F Sing
Modifications to the Patient Rule-Induction Method that utilize non-additive combinations of genetic and environmental effects to define partitions that predict ischemic heart disease.
Genetic epidemiology 2009;33(4):317-24.
2008: Vinod K Misra; Calvin J Hobel; Charles F Sing
Ethnic heterogeneity in the longitudinal effects of placental vascular blood flow on birthweight.
American journal of obstetrics and gynecology 2008;198(1):72.e1-8.
2007: Aida M Andrés; andrew clark; Lawrence Shimmin; Eric Boerwinkle; Charles F Sing; James E Hixson
Understanding the accuracy of statistical haplotype inference with sequence data of known phase.
Genetic epidemiology 2007;31(7):659-71.
2007: Jari H Stengård; Ruth Frikke-Schmidt; A Tybjaerg-Hansen; B G Nordestgaard; Charles F Sing
Variation in 5' promoter region of the APOE gene contributes to predicting ischemic heart disease (IHD) in the population at large: the Copenhagen City Heart Study.
Annals of human genetics 2007;71(Pt 6):762-71.
2007: Gregory E Dyson; Ruth Frikke-Schmidt; Børge G Nordestgaard; Anne Tybjaerg-Hansen; Charles F Sing
An application of the patient rule-induction method for evaluating the contribution of the Apolipoprotein E and Lipoprotein Lipase genes to predicting ischemic heart disease.
Genetic epidemiology 2007;31(6):515-27.
2007: Ruth Frikke-Schmidt; Charles F Sing; Børge G Nordestgaard; Rolf Steffensen; Anne Tybjaerg-Hansen
Subsets of SNPs define rare genotype classes that predict ischemic heart disease.
Human genetics 2007;120(6):865-77.
2006: Bret Payseur; andrew clark; James E Hixson; Eric Boerwinkle; Charles F Sing
Contrasting multi-site genotypic distributions among discordant quantitative phenotypes: the APOA1/C3/A4/A5 gene cluster and cardiovascular disease risk factors.
Genetic epidemiology 2006;30(6):508-18.
2006: Kathy Klos; Charles F Sing; Eric Boerwinkle; Sara C Hamon; Thomas J Rea; Andrew Clark; Myriam Fornage; James E Hixson
Consistent effects of genes involved in reverse cholesterol transport on plasma lipid and apolipoprotein levels in CARDIA participants.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(8):1828-36.
2006: C M Brown; Thomas J Rea; Sara C Hamon; James E Hixson; Eric Boerwinkle; andrew clark; Charles F Sing
The contribution of individual and pairwise combinations of SNPs in the APOA1 and APOC3 genes to interindividual HDL-C variability.
Journal of molecular medicine (Berlin, Germany) 2006;84(7):561-72.
2006: Jari H Stengård; Sharon L R Kardia; Sara C Hamon; Ruth Frikke-Schmidt; Anne Tybjaerg-Hansen; Veikko Salomaa; Eric Boerwinkle; Charles F Sing
Contribution of regulatory and structural variations in APOE to predicting dyslipidemia.
Journal of lipid research 2006;47(2):318-28.
2006: Thomas J Rea; Christine M Brown; Charles F Sing
Complex adaptive system models and the genetic analysis of plasma HDL-cholesterol concentration.
Perspectives in biology and medicine 2006;49(4):490-503.
2006: Sara C Hamon; Sharon L R Kardia; Eric Boerwinkle; Kiang Liu; Kathy Klos; andrew clark; Charles F Sing
Evidence for consistent intragenic and intergenic interactions between SNP effects in the APOA1/C3/A4/A5 gene cluster.
Human heredity 2006;61(2):87-96.
2005: andrew clark; Eric Boerwinkle; James E Hixson; Charles F Sing
Determinants of the success of whole-genome association testing.
Genome research 2005;15(11):1463-7.
2005: Kathy Klos; Sharon L R Kardia; James E Hixson; Stephen T Turner; Craig L Hanis; Eric Boerwinkle; Charles F Sing
Linkage analysis of plasma ApoE in three ethnic groups: multiple genes with context-dependent effects.
Annals of human genetics 2005;69(Pt 2):157-67.
2005: Kathy Klos; Sara C Hamon; andrew clark; Eric Boerwinkle; Kiang Liu; Charles F Sing
APOA5 polymorphisms influence plasma triglycerides in young, healthy African Americans and whites of the CARDIA Study.
Journal of lipid research 2005;46(3):564-71.
2005: Andrei Rodin; Thomas H Mosley; andrew clark; Charles F Sing; Eric Boerwinkle
Mining genetic epidemiology data with Bayesian networks application to APOE gene variation and plasma lipid levels.
Journal of computational biology : a journal of computational molecular cell biology 2005;12(1):1-11.
2005: Alan R Templeton; Taylor Maxwell; David Posada; Jari H Stengård; Eric Boerwinkle; Charles F Sing
Tree scanning: a method for using haplotype trees in phenotype/genotype association studies.
Genetics 2005;169(1):441-53.
2004: Sara C Hamon; J H Stengard; andrew clark; V Salomaa; Eric Boerwinkle; Charles F Sing
Evidence for non-additive influence of single nucleotide polymorphisms within the apolipoprotein E gene.
Annals of human genetics 2004;68(Pt 6):521-35.
2004: Ruth Frikke-Schmidt; Charles F Sing; Børge G Nordestgaard; Anne Tybjaerg-Hansen
Gender- and age-specific contributions of additional DNA sequence variation in the 5' regulatory region of the APOE gene to prediction of measures of lipid metabolism.
Human genetics 2004;115(4):331-45.
2004: Charles F Sing; Jari H Stengård; Sharon L R Kardia
Dynamic relationships between the genome and exposures to environments as causes of common human diseases.
World review of nutrition and dietetics 2004;93():77-91.
2003: Charles F Sing; Jari H Stengård; Sharon L R Kardia
Genes, environment, and cardiovascular disease.
Arteriosclerosis, thrombosis, and vascular biology 2003;23(7):1190-6.
2003: Stefan Kammerer; Lora L Burns-Hamuro; Yuliang Ma; Sara C Hamon; Jaume M Canaves; Michael M Shi; Matthew Nelson; Charles F Sing; Charles R Cantor; Susan S Taylor; Andreas Braun
Amino acid variant in the kinase binding domain of dual-specific A kinase-anchoring protein 2: a disease susceptibility polymorphism.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(7):4066-71.
2003: Sharon L R Kardia; Laura S Rozek; Julia Krushkal; Robert E Ferrell; Stephen T Turner; Richard Hutchinson; Andrew Brown; Charles F Sing; Eric Boerwinkle
Genome-wide linkage analyses for hypertension genes in two ethnically and geographically diverse populations.
American journal of hypertension 2003;16(2):154-7.
2002: Jari H Stengård; andrew clark; Kenneth M Weiss; Sharon L R Kardia; Deborah A Nickerson; Veikko Salomaa; Christian Ehnholm; Eric Boerwinkle; Charles F Sing
Contributions of 18 additional DNA sequence variations in the gene encoding apolipoprotein E to explaining variation in quantitative measures of lipid metabolism.
American journal of human genetics 2002;71(3):501-17.
2002: Suzanne Lussier-Cacan; Aline Bolduc; Marianne Xhignesse; Théophile Niyonsenga; Charles F Sing
Impact of alcohol intake on measures of lipid metabolism depends on context defined by gender, body mass index, cigarette smoking, and apolipoprotein E genotype.
Arteriosclerosis, thrombosis, and vascular biology 2002;22(5):824-31.
2001: Kathy Klos; Sharon L R Kardia; RE Ferrell; Stephen T Turner; Eric Boerwinkle; Charles F Sing
Genome-wide linkage analysis reveals evidence of multiple regions that influence variation in plasma lipid and apolipoprotein levels associated with risk of coronary heart disease.
Arteriosclerosis, thrombosis, and vascular biology 2001;21(6):971-8.
2001: M R Nelson; Sharon L R Kardia; R E Ferrell; Charles F Sing
A combinatorial partitioning method to identify multilocus genotypic partitions that predict quantitative trait variation.
Genome research 2001;11(3):458-70.
2000: KE Zerba; RE Ferrell; Charles F Sing
Complex adaptive systems and human health: the influence of common genotypes of the apolipoprotein E (ApoE) gene polymorphism and age on the relational order within a field of lipid metabolism traits.
Human genetics 2000;107(5):466-75.
2000: Gary L Schwartz; S T Turner; Jason Moore; Charles F Sing
Effect of time of day on intraindividual variability in ambulatory blood pressure.
American journal of hypertension 2000;13(11):1203-9.
2000: Alan R Templeton; Kenneth M Weiss; D A Nickerson; Eric Boerwinkle; Charles F Sing
Cladistic structure within the human Lipoprotein lipase gene and its implications for phenotypic association studies.
Genetics 2000;156(3):1259-75.
2000: Deborah A Nickerson; Scott L Taylor; Stephanie M Fullerton; Kenneth M Weiss; andrew clark; Jari H Stengård; Veikko Salomaa; Eric Boerwinkle; Charles F Sing
Sequence diversity and large-scale typing of SNPs in the human apolipoprotein E gene.
Genome research 2000;10(10):1532-45.
2000: Stephanie M Fullerton; andrew clark; Kenneth M Weiss; Deborah A Nickerson; Scott L Taylor; J H Stengârd; Veikko Salomaa; E Vartiainen; M Perola; Eric Boerwinkle; Charles F Sing
Apolipoprotein E variation at the sequence haplotype level: implications for the origin and maintenance of a major human polymorphism.
American journal of human genetics 2000;67(4):881-900.
2000: Molly S Bray; Julia Krushkal; L Li; R Ferrell; Sharon L R Kardia; Charles F Sing; Stephen T Turner; Eric Boerwinkle
Positional genomic analysis identifies the beta(2)-adrenergic receptor gene as a susceptibility locus for human hypertension.
Circulation 2000;101(25):2877-82.
2000: Suzanne Lussier-Cacan; A Bolduc; Marianne Xhignesse; Théophile Niyonsenga; P W Connelly; Charles F Sing
Impact of age and body size on inter-individual variation in measures of lipid metabolism: influence of gender and apolipoprotein E genotype.
Clinical genetics 2000;57(1):35-47.
2000: Gary L Schwartz; S T Turner; Jason Moore; Charles F Sing
Predictors of interindividual variation in ambulatory blood pressure and their time or activity dependence.
American journal of hypertension 2000;13(1 Pt 1):52-60.
2000: Alan R Templeton; andrew clark; Kenneth M Weiss; D A Nickerson; Eric Boerwinkle; Charles F Sing
Recombinational and mutational hotspots within the human lipoprotein lipase gene.
American journal of human genetics 2000;66(1):69-83.
1999: Suzanne Lussier-Cacan; Marianne Xhignesse; A M Kessling; Jean Davignon; Charles F Sing
Sources of variation in plasma lipid and lipoprotein traits in a sample selected for health.
American journal of epidemiology 1999;150(11):1229-37.
1999: Jari H Stengård; Sharon L R Kardia; M Tervahauta; Christian Ehnholm; A Nissinen; Charles F Sing
Utility of the predictors of coronary heart disease mortality in a longitudinal study of elderly Finnish men aged 65 to 84 years is dependent on context defined by Apo E genotype and area of residence.
Clinical genetics 1999;56(5):367-77.
1999: Stephen T Turner; Eric Boerwinkle; Charles F Sing
Context-dependent associations of the ACE I/D polymorphism with blood pressure.
Hypertension 1999;34(4 Pt 2):773-8.
1999: M R Nelson; Sharon L R Kardia; RE Ferrell; Charles F Sing
Influence of apolipoprotein E genotype variation on the means, variances, and correlations of plasma lipids and apolipoproteins in children.
Annals of human genetics 1999;63(Pt 4):311-28.
1999: Julia Krushkal; R Ferrell; Stephen Mockrin; Stephen T Turner; Charles F Sing; Eric Boerwinkle
Genome-wide linkage analyses of systolic blood pressure using highly discordant siblings.
Circulation 1999;99(11):1407-10.
1999: Sharon L R Kardia; MB Haviland; RE Ferrell; Charles F Sing
The relationship between risk factor levels and presence of coronary artery calcification is dependent on apolipoprotein E genotype.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(2):427-35.
1998: KE Zerba; RE Ferrell; Charles F Sing
Genetic structure of five susceptibility gene regions for coronary artery disease: disequilibria within and among regions.
Human genetics 1998;103(3):346-54.
1998: Julia Krushkal; M Xiong; R Ferrell; Charles F Sing; Stephen T Turner; Eric Boerwinkle
Linkage and association of adrenergic and dopamine receptor genes in the distal portion of the long arm of chromosome 5 with systolic blood pressure variation.
Human molecular genetics 1998;7(9):1379-83.
1998: Jari H Stengård; Kenneth M Weiss; Charles F Sing
An ecological study of association between coronary heart disease mortality rates in men and the relative frequencies of common allelic variations in the gene coding for apolipoprotein E.
Human genetics 1998;103(2):234-41.
1998: andrew clark; Kenneth M Weiss; Deborah A Nickerson; Scott L Taylor; Anne V Buchanan; Jari H Stengård; Veikko Salomaa; E Vartiainen; M Perola; Eric Boerwinkle; Charles F Sing
Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase.
American journal of human genetics 1998;63(2):595-612.
1998: Deborah A Nickerson; Scott L Taylor; Kenneth M Weiss; andrew clark; R G Hutchinson; Jari H Stengård; Veikko Salomaa; E Vartiainen; Eric Boerwinkle; Charles F Sing
DNA sequence diversity in a 9.7-kb region of the human lipoprotein lipase gene.
Nature genetics 1998;19(3):233-40.
1998: Sharon L R Kardia; MB Haviland; Charles F Sing
Correlates of family history of coronary artery disease in children.
Journal of clinical epidemiology 1998;51(6):473-86.
1998: Myriam Fornage; C I Amos; S Kardia; Charles F Sing; S T Turner; E Boerwinkle
Variation in the region of the angiotensin-converting enzyme gene influences interindividual differences in blood pressure levels in young white males.
Circulation 1998;97(18):1773-9.
1997: S L Kardia; Charles F Sing; Stephen T Turner
The response of renal plasma flow to angiotensin II infusion in a population-based sample and its association with the parental history of essential hypertension.
Journal of hypertension 1997;15(5):483-93.
1997: Jari H Stengård; KE Zerba; S T Turner; Charles F Sing
A biometrical study of the relationship between sodium-lithium countertransport and triglycerides.
Annals of human genetics 1997;61(Pt 2):121-36.
1997: Jason Moore; S L Reilly; R E Ferrell; Charles F Sing
The role of the apolipoprotein E polymorphism in the prediction of coronary artery disease age of onset.
Clinical genetics 1997;51(1):22-5.
1997: MB Haviland; RE Ferrell; Charles F Sing
Association between common alleles of the low-density lipoprotein receptor gene region and interindividual variation in plasma lipid and apolipoprotein levels in a population-based sample from Rochester, Minnesota.
Human genetics 1997;99(1):108-14.
1996: Stephen T Turner; Charles F Sing
Erythrocyte sodium transport and the probability of having hypertension.
Journal of hypertension 1996;14(7):829-37.
1996: Timothy R Rebbeck; Stephen T Turner; Charles F Sing
Probability of having hypertension: effects of sex, history of hypertension in parents, and other risk factors.
Journal of clinical epidemiology 1996;49(7):727-34.
1996: K E Zerba; RE Ferrell; Charles F Sing
Genotype-environment interaction: apolipoprotein E (ApoE) gene effects and age as an index of time and spatial context in the human.
Genetics 1996;143(1):463-78.
1996: Jari H Stengård; J Pekkanen; Christian Ehnholm; A Nissinen; Charles F Sing
Genotypes with the apolipoprotein epsilon4 allele are predictors of coronary heart disease mortality in a longitudinal study of elderly Finnish men.
Human genetics 1996;97(5):677-84.
1996: Gary L Schwartz; Stephen T Turner; Charles F Sing
Association of genetic variation with interindividual variation in ambulatory blood pressure.
Journal of hypertension 1996;14(2):251-8.
1996: Charles F Sing; MB Haviland; S L Reilly
Genetic architecture of common multifactorial diseases.
Ciba Foundation symposium 1996;197():211-29; discussion 229-32.
1995: MB Haviland; S Lussier-Cacan; J Davignon; Charles F Sing
Impact of apolipoprotein E genotype variation on means, variances, and correlations of plasma lipid, lipoprotein, and apolipoprotein traits in octogenarians.
American journal of medical genetics 1995;58(4):315-31.
1995: Myriam Fornage; S T Turner; Charles F Sing; Eric Boerwinkle
Variation at the M235T locus of the angiotensinogen gene and essential hypertension: a population-based case-control study from Rochester, Minnesota.
Human genetics 1995;96(3):295-300.
1995: MB Haviland; A M Kessling; J Davignon; Charles F Sing
Cladistic analysis of the apolipoprotein AI-CIII-AIV gene cluster using a healthy French Canadian sample. I. Haploid analysis.
Annals of human genetics 1995;59(Pt 2):211-31.
1995: M Roy; Charles F Sing; C Betard; J Davignon
Impact of a common mutation of the LDL receptor gene, in French-Canadian patients with familial hypercholesterolemia, on means, variances and correlations among traits of lipid metabolism.
Clinical genetics 1995;47(2):59-67.
1995: Jari H Stengård; K E Zerba; J Pekkanen; Christian Ehnholm; A Nissinen; Charles F Sing
Apolipoprotein E polymorphism predicts death from coronary heart disease in a longitudinal study of elderly Finnish men.
Circulation 1995;91(2):265-9.
1994: S L Reilly; RE Ferrell; Charles F Sing
The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, MN. III. Correlations and covariances.
American journal of human genetics 1994;55(5):1001-18.
1994: J Ferrières; Charles F Sing; M Roy; Jean Davignon; Suzanne Lussier-Cacan
Apolipoprotein E polymorphism and heterozygous familial hypercholesterolemia. Sex-specific effects.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(10):1553-60.
1994: Charles F Sing; K E Zerba; S L Reilly
Traversing the biological complexity in the hierarchy between genome and CAD endpoints in the population at large.
Clinical genetics 1994;46(1 Spec No):6-14.
1994: S L Reilly; Charles F Sing; Michael A Savageau; Stephen T Turner
Analysis of systems influencing renal hemodynamics and sodium excretion. I. Biochemical systems theory.
Integrative physiological and behavioral science : the official journal of the Pavlovian Society 1994;29(1):55-73.
1993: Timothy R Rebbeck; Stephen T Turner; Charles F Sing
Sodium-lithium countertransport genotype and the probability of hypertension in adults.
Hypertension 1993;22(4):560-8.
1993: Alan R Templeton; Charles F Sing
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. IV. Nested analyses with cladogram uncertainty and recombination.
Genetics 1993;134(2):659-69.
1992: Charles F Sing; MB Haviland; A R Templeton; K E Zerba; S L Reilly
Biological complexity and strategies for finding DNA variations responsible for inter-individual variation in risk of a common chronic disease, coronary artery disease.
Annals of medicine 1992;24(6):539-47.
1992: S L Reilly; RE Ferrell; B A Kottke; Charles F Sing
The gender-specific apolipoprotein E genotype influence on the distribution of plasma lipids and apolipoproteins in the population of Rochester, Minnesota. II. Regression relationships with concomitants.
American journal of human genetics 1992;51(6):1311-24.
1992: Stephen T Turner; Timothy R Rebbeck; Charles F Sing
Sodium-lithium countertransport and probability of hypertension in Caucasians 47 to 89 years old.
Hypertension 1992;20(6):841-50.
1992: Gary L Schwartz; Stephen T Turner; Charles F Sing
Twenty-four-hour blood pressure profiles in normotensive sons of hypertensive parents.
Hypertension 1992;20(6):834-40.
1992: Alan R Templeton; Keith A Crandall; Charles F Sing
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping and DNA sequence data. III. Cladogram estimation.
Genetics 1992;132(2):619-33.
1992: Charles F Sing; MB Haviland; K E Zerba; A R Templeton
Application of cladistics to the analysis of genotype-phenotype relationships.
European journal of epidemiology 1992;8 Suppl 1():3-9.
1991: S L Reilly; RE Ferrell; B A Kottke; M I Kamboh; Charles F Sing
The gender-specific apolipoprotein E genotype influence on the distribution of lipids and apolipoproteins in the population of Rochester, MN. I. Pleiotropic effects on means and variances.
American journal of human genetics 1991;49(6):1155-66.
1991: K E Zerba; A M Kessling; J Davignon; Charles F Sing
Genetic structure and the search for genotype-phenotype relationships: an example from disequilibrium in the Apo B gene region.
Genetics 1991;129(2):525-33.
1991: Jaakko Kaprio; RE Ferrell; B A Kottke; M I Kamboh; Charles F Sing
Effects of polymorphisms in apolipoproteins E, A-IV, and H on quantitative traits related to risk for cardiovascular disease.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(5):1330-48.
1991: MB Haviland; A M Kessling; J Davignon; Charles F Sing
Estimation of Hardy-Weinberg and pairwise disequilibrium in the apolipoprotein AI-CIII-AIV gene cluster.
American journal of human genetics 1991;49(2):350-65.
1991: M Xhignesse; Suzanne Lussier-Cacan; Charles F Sing; A M Kessling; Jean Davignon
Influences of common variants of apolipoprotein E on measures of lipid metabolism in a sample selected for health.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1991;11(4):1100-10.
1991: L Pérusse; P P Moll; Charles F Sing
Evidence that a single gene with gender- and age-dependent effects influences systolic blood pressure determination in a population-based sample.
American journal of human genetics 1991;49(1):94-105.
1990: K E Zerba; J S Friedlaender; Charles F Sing
Heterogeneity of the blood pressure distribution among Solomon Islands societies with increasing acculturation.
American journal of physical anthropology 1990;81(4):493-511.
1990: B A Kottke; J S Friedlaender; K E Zerba; Charles F Sing
Lipid and apolipoprotein levels in six Solomon Island societies differ from those in a U.S. white population.
American journal of physical anthropology 1990;81(4):483-91.
1990: S L Reilly; B A Kottke; Charles F Sing
The effects of generation and gender on the joint distributions of lipid and apolipoprotein phenotypes in the population at large.
Journal of clinical epidemiology 1990;43(9):921-40.
1990: Charles F Sing; Jaakko Kaprio; L Perusse; P P Moll
Genetic differences in risk of disease within and between populations.
World review of nutrition and dietetics 1990;63():220-35.
1990: Charles F Sing; P P Moll
Genetics of atherosclerosis.
Annual review of genetics 1990;24():171-87.
1989: Jaakko Kaprio; RE Ferrell; B A Kottke; Charles F Sing
Smoking and reverse cholesterol transport: evidence for gene-environment interaction.
Clinical genetics 1989;36(4):266-8.
1989: Stephen T Turner; W H Weidman; V V Michels; T J Reed; C L Ormson; T Fuller; Charles F Sing
Distribution of sodium-lithium countertransport and blood pressure in Caucasians five to eighty-nine years of age.
Hypertension 1989;13(4):378-91.
1989: Charles F Sing; P P Moll
Genetics of variability of CHD risk.
International journal of epidemiology 1989;18(3 Suppl 1):S183-95.
1988: Alan R Templeton; Charles F Sing; A Kessling; S Humphries
A cladistic analysis of phenotype associations with haplotypes inferred from restriction endonuclease mapping. II. The analysis of natural populations.
Genetics 1988;120(4):1145-54.
1988: Gail P Jarvik; J Davignon; H Mailloux; Charles F Sing
Sources of interindividual variation in the quantitative levels of apolipoprotein B in pedigrees ascertained through a lipid clinic.
American journal of human genetics 1988;43(3):311-21.
1988: Jean Davignon; D Bouthillier; A C Nestruck; Charles F Sing
Apolipoprotein E polymorphism and atherosclerosis: insight from a study in octogenarians.
Transactions of the American Clinical and Climatological Association 1988;99():100-10.
1988: Jean Davignon; R E Gregg; Charles F Sing
Apolipoprotein E polymorphism and atherosclerosis.
Arteriosclerosis (Dallas, Tex.) 1988;8(1):1-21.
1987: A R Templeton; E Boerwinkle; Charles F Sing
A cladistic analysis of phenotypic associations with haplotypes inferred from restriction endonuclease mapping. I. Basic theory and an analysis of alcohol dehydrogenase activity in Drosophila.
Genetics 1987;117(2):343-51.
1987: R E Little; Charles F Sing
Father's drinking and infant birth weight: report of an association.
Teratology 1987;36(1):59-65.
1987: A C Nestruck; D Bouthillier; Charles F Sing; Jean Davignon
Apolipoprotein E polymorphism and plasma cholesterol response to probucol.
Metabolism: clinical and experimental 1987;36(8):743-7.
1987: Eric Boerwinkle; Charles F Sing
The use of measured genotype information in the analysis of quantitative phenotypes in man. III. Simultaneous estimation of the frequencies and effects of the apolipoprotein E polymorphism and residual polygenetic effects on cholesterol, betalipoprotein and triglyceride levels.
Annals of human genetics 1987;51(Pt 3):211-26.
1987: E Boerwinkle; S Visvikis; D Welsh; Josiane Steinmetz; S M Hanash; Charles F Sing
The use of measured genotype information in the analysis of quantitative phenotypes in man. II. The role of the apolipoprotein E polymorphism in determining levels, variability, and covariability of cholesterol, betalipoprotein, and triglycerides in a sample of unrelated individuals.
American journal of medical genetics 1987;27(3):567-82.
1987: D J Odenheimer; Sharada A Sarnaik; C F Whitten; D L Rucknagel; Charles F Sing
The relationship between fetal hemoglobin and disease severity in children with sickle cell anemia.
American journal of medical genetics 1987;27(3):525-35.
1987: P B Furspan; P T Jokelainen; Charles F Sing; D F Bohr
Genetic relationship between a lymphocyte membrane abnormality and blood pressure in spontaneously hypertensive stroke prone and Wistar-Kyoto rats.
Journal of hypertension 1987;5(3):293-7.
1987: R E Little; Charles F Sing
Genetic and environmental influences on human birth weight.
American journal of human genetics 1987;40(6):512-26.
1987: Charles F Sing; E A Boerwinkle
Genetic architecture of inter-individual variability in apolipoprotein, lipoprotein and lipid phenotypes.
Ciba Foundation symposium 1987;130():99-127.
1987: Alan R Templeton; J S Johnston; Charles F Sing
The proximate and ultimate control of aging in Drosophila and humans.
Basic life sciences 1987;42():123-33.
1987: S T Turner; E Boerwinkle; M Johnson; E Richelson; Charles F Sing
Sodium-lithium countertransport in ambulatory hypertensive and normotensive patients.
Hypertension 1987;9(1):24-34.
1986: C A Bruner; J H Myers; Charles F Sing; P T Jokelainen; R Clinton Webb
Genetic basis for altered vascular responses to ouabain and potassium-free solution in hypertension.
The American journal of physiology 1986;251(6 Pt 2):H1276-82.
1986: C A Bruner; J H Myers; Charles F Sing; P T Jokelainen; R Clinton Webb
Genetic association of hypertension and vascular changes in stroke-prone spontaneously hypertensive rats.
Hypertension 1986;8(10):904-10.
1986: F M Sessler; P T Jokelainen; Charles F Sing; A M Strack; Richard L Malvin
Renin heterogeneity in stroke-prone hypertensive and normotensive rats.
The American journal of physiology 1986;251(4 Pt 1):E367-72.
1986: E Boerwinkle; Charles F Sing
Bias of the contribution of single-locus effects to the variance of a quantitative trait.
American journal of human genetics 1986;39(1):137-44.
1986: R E Little; Charles F Sing
Association of father's drinking and infant's birth weight.
The New England journal of medicine 1986;314(25):1644-5.
1986: E Boerwinkle; R Chakraborty; Charles F Sing
The use of measured genotype information in the analysis of quantitative phenotypes in man. I. Models and analytical methods.
Annals of human genetics 1986;50(Pt 2):181-94.
1986: E Richelson; K Snyder; J Carlson; M Johnson; S Turner; A Lumry; E Boerwinkle; Charles F Sing
Lithium ion transport by erythrocytes of randomly selected blood donors and manic-depressive patients: lack of association with affective illness.
The American journal of psychiatry 1986;143(4):457-62.
1986: P P Moll; Charles F Sing; R R Williams; S J Mao; B A Kottke
The genetic determination of plasma apolipoprotein A-I levels measured by radioimmunoassay: a study of high-risk pedigrees.
American journal of human genetics 1986;38(3):361-72.
1986: R Kuick; E Boerwinkle; S M Hanash; Charles F Sing
A statistical analysis of spot variation using the two-dimensional polyacrylamide gel electrophoresis.
Computers and biomedical research, an international journal 1986;19(1):90-102.
1986: W R Clarke; H G Schrott; T L Burns; Charles F Sing; R M Lauer
Aggregation of blood pressure in the families of children with labile high systolic blood pressure. The Muscatine Study.
American journal of epidemiology 1986;123(1):67-80.
1986: E Boerwinkle; S T Turner; R Weinshilboum; M Johnson; E Richelson; Charles F Sing
Analysis of the distribution of erythrocyte sodium lithium countertransport in a sample representative of the general population.
Genetic epidemiology 1986;3(5):365-78.
1986: Charles F Sing; E Boerwinkle; S T Turner
Genetics of primary hypertension.
Clinical and experimental hypertension. Part A, Theory and practice 1986;8(4-5):623-51.
1986: J G Mongeau; P Biron; Charles F Sing
The influence of genetics and household environment upon the variability of normal blood pressure: the Montreal Adoption Survey.
Clinical and experimental hypertension. Part A, Theory and practice 1986;8(4-5):653-60.
1985: S T Turner; M Johnson; E Boerwinkle; E Richelson; H F Taswell; Charles F Sing
Sodium-lithium countertransport and blood pressure in healthy blood donors.
Hypertension 1985;7(6 Pt 1):955-62.
1985: Gail P Jarvik; R P Erickson; J Schultz; Charles F Sing
Failure to detect association of isolated cleft palate with HLA antigens.
Journal of immunogenetics 1985;12(4-5):259-62.
1985: R P Erickson; L A Heidel; J Kapur; J M Karolyi; D J Odenheimer; Gail P Jarvik; J S Schultz; Charles F Sing
HLA antigens, phytohemagglutinin stimulation, and corticosteroid response.
American journal of human genetics 1985;37(4):761-70.
1985: Charles F Sing; J Davignon
Role of the apolipoprotein E polymorphism in determining normal plasma lipid and lipoprotein variation.
American journal of human genetics 1985;37(2):268-85.
1985: Charles F Sing; E Boerwinkle; P P Moll
Strategies for elucidating the phenotypic and genetic heterogeneity of a chronic disease with a complex etiology.
Progress in clinical and biological research 1985;194():39-66.
1985: R P Erickson; Gail P Jarvik; J M Karolyi; J Kapur; D J Odenheimer; J S Schultz; Charles F Sing
HLA-B18 is associated with decreased levels of isoproterenol-stimulated cAMP in lymphocytes.
American journal of human genetics 1985;37(1):124-32.
1984: D Bouthillier; A C Nestruck; R Milne; Charles F Sing; A Barbeau; Jean Davignon
Distribution of apolipoprotein E phenotypes in Friedreich's ataxia.
The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques 1984;11(4 Suppl):626-30.
1984: P Coyle; D J Odenheimer; Charles F Sing
Cerebral infarction after middle cerebral artery occlusion in progenies of spontaneously stroke-prone and normal rats.
Stroke; a journal of cerebral circulation 1984;15(4):711-6.
1984: D J Odenheimer; C F Whitten; D A Rucknagel; Sharada A Sarnaik; Charles F Sing
Stability over time of hematological variables in 197 children with sickle cell anemia.
American journal of medical genetics 1984;18(3):461-70.
1984: P P Moll; Charles F Sing; S Lussier-Cacan; J Davignon
An application of a model for a genotype-dependent relationship between a concomitant (age) and a quantitative trait (LDL cholesterol) in pedigree data.
Genetic epidemiology 1984;1(4):301-14.
1984: E Boerwinkle; S T Turner; Charles F Sing
The role of the genetics of sodium lithium countertransport in the determination of blood pressure variability in the population at large.
Progress in clinical and biological research 1984;165():479-507.
1984: D Rucknagel; S Ferrucci; C F Whitten; I Sarniak; D Odenheimer; Charles F Sing; C Bruzdzinski
alpha-Thalassemia and HbF concentration in sickle cell anemia.
Progress in clinical and biological research 1984;165():103-20.
1983: C L Hanis; Charles F Sing; W R Clarke; H G Schrott
Multivariate models for human genetic analysis: aggregation, coaggregation, and tracking of systolic blood pressure and weight.
American journal of human genetics 1983;35(6):1196-210.
1983: D J Odenheimer; C F Whitten; D L Rucknagel; Sharada A Sarnaik; Charles F Sing
Heterogeneity of sickle-cell anemia based on a profile of hematological variables.
American journal of human genetics 1983;35(6):1224-40.
1983: D Bouthillier; Charles F Sing; J Davignon
Apolipoprotein E phenotyping with a single gel method: application to the study of informative matings.
Journal of lipid research 1983;24(8):1060-9.
1983: R L Clark; E Boerwinkle; G J Brewer; Charles F Sing
Studies of enzyme polymorphism in the Kamuela population of Drosophila mercatorum. III. Effects of variation at the alpha GPD locus and subflight stress on the energy charge and glycolytic intermediate concentrations.
Genetics 1983;104(4):661-75.
1983: J L Annest; Charles F Sing; P Biron; J G Mongeau
Familial aggregation of blood pressure and weight in adoptive families. III. Analysis of the role of shared genes and shared household environment in explaining family resemblance for height, weight and selected weight/height indices.
American journal of epidemiology 1983;117(4):492-506.
1983: P P Moll; Charles F Sing; W H Weidman; H Gordon; R D Ellefson; P A Hodgson; B A Kottke
Total cholesterol and lipoproteins in school children: prediction of coronary heart disease in adult relatives.
Circulation 1983;67(1):127-34.
1983: J Davignon; S Lussier-Cacan; A Gattereau; P P Moll; Charles F Sing
Interaction of two lipid disorders in a large French-Canadian kindred.
Arteriosclerosis (Dallas, Tex.) 1983;3(1):13-22.
1982: R L Clark; G J Brewer; Charles F Sing
Studies of enzyme polymorphisms in the Kamuela population of Drosophila mercatorum. II. Evaluation of glycolytic intermediates.
Biochemical genetics 1982;20(11-12):1085-1103.
1982: Charles F Sing; D R Risser; W F Howatt; R P Erickson
Phenotypic heterogeneity in cystic fibrosis.
American journal of medical genetics 1982;13(2):179-95.
1981: R L Clark; A R Templeton; Charles F Sing
Studies of Enzyme Polymorphisms in the Kamuela Population of D. MERCATORUM. I. Estimation of the Level of Polymorphism.
Genetics 1981;98(3):597-611.
1981: J S Schultz; A E Good; Charles F Sing; J Kapur
HLA profile and Reiter's syndrome.
Clinical genetics 1981;19(3):159-67.
1981: J D Orr; Charles F Sing; P P Moll
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan--VI. A search for genotype by environment interaction.
Journal of chronic diseases 1981;34(11):545-59.
1980: T E Gilroy; G J Brewer; Charles F Sing
Genetic control of glycolysis in human erythrocytes.
Genetics 1980;94(3):719-32.
1979: J L Annest; Charles F Sing; P Biron; J G Mongeau
Familial aggregation of blood pressure and weight in adoptive families. II. Estimation of the relative contributions of genetic and common environmental factors to blood pressure correlations between family members.
American journal of epidemiology 1979;110(4):492-503.
1979: J L Annest; Charles F Sing; P Biron; J G Mongeau
Familial aggregation of blood pressure and weight in adoptive families. I. Comparisons of blood pressure and weight statistics among families with adopted, natural, or both natural and adopted children.
American journal of epidemiology 1979;110(4):479-91.
1979: R P Erickson; M S Butley; Charles F Sing
H-2 and non-H-2 determined strain variation in palatal shelf and tongue adenosine 3':5' cyclic monophosphate: a possible role in the etiology of steroid-induced cleft palate.
Journal of immunogenetics 1979;6(4):253-62.
1979: Charles F Sing; J D Orr; P P Moll
The contribution of genes controlling total serum cholesterol to prediction of cardiovascular disease risk in the general population.
Progress in clinical and biological research 1979;32():587-618.
1979: P P Moll; R Powsner; Charles F Sing
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. V. Variance components estimated from pedigrees.
Annals of human genetics 1979;42(3):343-54.
1979: P P Moll; Charles F Sing
Sampling strategies for the analysis of quantitative traits.
Progress in clinical and biological research 1979;32():307-42.
1978: Charles F Sing; J D Orr
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. IV. Separation of polygene from common environment effects.
American journal of human genetics 1978;30(5):491-504.
1978: P P Moll; Charles F Sing; G J Brewer; T E Gilroy
Multivariate analysis of the genetic effects on red blood cell glycolysis.
Progress in clinical and biological research 1978;21():385-409.
1978: T E Gilroy; G J Brewer; Charles F Sing
Quantitative genetics of human erythrocyte glycolytic intermediate concentrations.
Progress in clinical and biological research 1978;21():363-83.
1977: P P Moll; Charles F Sing; G J Brewer
A path analysis of the causal relationships between red cell glycolytic intermediates, ADP and ATP in sickle cell anemia.
Bio Systems 1977;9(4):245-56.
1977: D G Smith; Charles F Sing
Genetic-environmental interactions in the variation of blood pressure in Tecumseh, Michigan.
Journal of chronic diseases 1977;30(12):781-91.
1976: Charles F Sing; J D Orr
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. III. Identification of genetic effects using 12 polymorphic genetic blood marker systems.
American journal of human genetics 1976;28(5):453-64.
1976: D G Smith; Charles F Sing
Sampling biases in longitudinal genetic-epidemiologic surveys.
Human biology 1976;48(3):529-39.
1976: A R Templeton; H L Carson; Charles F Sing
The population genetics of parthenogenetic strains of Drosophila mercatorium. II The capacity for parthenogenesis in a natural, bisexual population.
Genetics 1976;82(3):527-42.
1976: A R Templeton; Charles F Sing; B Brokaw
The unit of selection in Drosophila mercatorum. I. The interation of selection and meiosis in parthenogenetic strains.
Genetics 1976;82(2):349-76.
1976: D G Smith; Charles F Sing
The effect of sample attrition on the frequency distribution of blood pressure and genetic marker phenotypes representing a natural unselected community: Tecumseh, Michigan.
American journal of physical anthropology 1976;44(1):139-49.
1975: Charles F Sing; E D Rothman
A consideration of the chi-square test of Hardy--Weinberg equilibrium in a non-multinomial situation.
Annals of human genetics 1975;39(2):141-5.
1975: Charles F Sing; M A Chamberlain; W D Block; S Feiler
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan. I. Analysis of the frequency distribution for evidence of a genetic polymorphism.
American journal of human genetics 1975;27(3):333-47.
1975: J D Orr; Charles F Sing; W D Block
Analysis of genetic and environmental sources of variation in serum cholesterol in Tecumseh, Michigan: II. The role of education, occupation, and income.
Social biology 1975;22(1):34-43.
1974: E D Rothman; Charles F Sing; A R Templeton
A model for analysis of population structure.
Genetics 1974;78(3):943-60.
1974: G J Brewer; Charles F Sing; J W Eaton; J V Weil; L F Brewer; R F Grover
Effects on hemoglobin oxygen affinity of smoking in residents of intermediate altitude.
The Journal of laboratory and clinical medicine 1974;84(2):191-205.
1974: Charles F Sing; J S Schultz; D C Shreffler
The genetics of the Lp antigen. II. A family study and proposed models of genetic control.
Annals of human genetics 1974;38(1):47-56.
1974: J S Schultz; D C Schreffler; Charles F Sing; N R Harvie
The genetics of the Lp antigen. I. Its quantitation and distribution in a sample population.
Annals of human genetics 1974;38(1):39-46.
1973: Charles F Sing; G J Brewer; B Thirtle
Inherited biochemical variation in Drosophila melanogaster: noise or signal? I. Single-locus analysis.
Genetics 1973;75(2):381-404.
1972: P Sinnock; Charles F Sing
Analysis of multilocus genetic systems in Tecumseh, Michigan. II. Consideration of the correlation between nonalleles in gametes.
American journal of human genetics 1972;24(4):393-415.
1972: P Sinnock; Charles F Sing
Analysis of multilocus genetic systems in Tecumseh, Michigan. I. Definition of the data set and tests for goodness-of-fit to expectations based on gene, gamete, and single-locus phenotype frequencies.
American journal of human genetics 1972;24(4):381-92.
1971: Charles F Sing; G J Brewer
Evidence for nonrandom multiplicity of gene products in 22 plant genera.
Biochemical genetics 1971;5(3):243-51.
1971: Charles F Sing; D C Shreffler; J V Neel; J A Napier
Studies on genetic selection in a completely ascertained caucasian population. II. Family analyses of 11 blood group systems.
American journal of human genetics 1971;23(2):164-98.
1971: D C Shreffler; Charles F Sing; J V Neel; H Gershowitz; J A Napier
Studies on genetic selection in a completely ascertained caucasian population. I. Frequencies, age and sex effects, and phenotype associations for 12 blood group systems.
American journal of human genetics 1971;23(2):150-63.
1970: L R Weitkamp; S A Guttormsen; D C Shreffler; Charles F Sing; J A Napier
Genetic linkage relations of the loci for 6-phosphogluconate dehydrogenase and adenosine deaminase in man.
American journal of human genetics 1970;22(2):216-20.
1969: G J Brewer; Charles F Sing; E R Sears
Studies of isozyme patterns in nullisomic-tetrasomic combinations of hexaploid wheat.
Proceedings of the National Academy of Sciences of the United States of America 1969;64(4):1224-9.
1969: L R Weitkamp; Charles F Sing; D C Shreffler; S A Guttormsen
The genetic linkage relations of adenylate kinase: further data on the ABO-AK linkage group.
American journal of human genetics 1969;21(6):600-5.
1969: C Knutsen; Charles F Sing; G J Brewer
Hexokinase isozyme variability in Drosophila robusta.
Biochemical genetics 1969;3(5):475-83.
1968: Ananda S Prasad; Liborio Tranchida; E T Konno; L Berman; S Albert; Charles F Sing; G J Brewer
Hereditary sideroblastic anemia and glucose-6-phosphate dehydrogenase deficiency in a Negro family.
The Journal of clinical investigation 1968;47(6):1415-24.
1967: J W MacCluer; R Griffith; Charles F Sing; W J Schull
Some genetic programs to supplement self-instruction in FORTRAN.
American journal of human genetics 1967;19(3 Pt 1):189-221.