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Tobias Sing

Research Profile

Living Beings

HIV-1
HIV

Physiology

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HIV Infections

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Publications

TOP 3
Stefano Alcaro; Claudia Alteri; Anna Artese; Ada Bertoli; Vincent Calvez; Francesca Ceccherini-Silberstein; Giosuè Costa; Diane Descamps; Philippe Flandre; Federica Forbici; Anne-Genevieve Marcelin; Bernard Masquelier; Francesco Ortuso; Lucia Parrotta; Carlo Federico Perno; Maria Mercedes Santoro; Tobias Sing; Valentina Svicher
Docking analysis and resistance evaluation of clinically relevant mutations associated with the HIV-1 non-nucleoside reverse transcriptase inhibitors nevirapine, efavirenz and etravirine.
Maria Trignetti; Tobias Sing; Valentina Svicher; Maria Mercedes Santoro; Federica Forbici; Roberta D'Arrigo; Maria Concetta Bellocchi; Mario Santoro; Patrizia Marconi; Mauro Zaccarelli; Maria Paola Trotta; Rita Bellagamba; Pasquale Narciso; Andrea Antinori; Thomas Lengauer; Carlo Federico Perno; Francesca Ceccherini-Silberstein
Dynamics of NRTI resistance mutations during therapy interruption.
Andrew J Low; David Marchant; Chanson J Brumme; Zabrina L Brumme; Winnie Dong; Tobias Sing; Hogg Robert; Julio S G Montaner; Vikram Gill; Peter K Cheung; P Richard Harrigan
CD4-dependent characteristics of coreceptor use and HIV type 1 V3 sequence in a large population of therapy-naive individuals.

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All Publications

2011: Stefano Alcaro; Claudia Alteri; Anna Artese; Ada Bertoli; Vincent Calvez; Francesca Ceccherini-Silberstein; Giosuè Costa; Diane Descamps; Philippe Flandre; Federica Forbici; Anne-Genevieve Marcelin; Bernard Masquelier; Francesco Ortuso; Lucia Parrotta; Carlo Federico Perno; Maria Mercedes Santoro; Tobias Sing; Valentina Svicher
Docking analysis and resistance evaluation of clinically relevant mutations associated with the HIV-1 non-nucleoside reverse transcriptase inhibitors nevirapine, efavirenz and etravirine.
ChemMedChem 2011;6(12):2203-13.
2009: Maria Trignetti; Tobias Sing; Valentina Svicher; Maria Mercedes Santoro; Federica Forbici; Roberta D'Arrigo; Maria Concetta Bellocchi; Mario Santoro; Patrizia Marconi; Mauro Zaccarelli; Maria Paola Trotta; Rita Bellagamba; Pasquale Narciso; Andrea Antinori; Thomas Lengauer; Carlo Federico Perno; Francesca Ceccherini-Silberstein
Dynamics of NRTI resistance mutations during therapy interruption.
AIDS research and human retroviruses 2009;25(1):57-64.
2008: Andrew J Low; David Marchant; Chanson J Brumme; Zabrina L Brumme; Winnie Dong; Tobias Sing; Hogg Robert; Julio S G Montaner; Vikram Gill; Peter K Cheung; P Richard Harrigan
CD4-dependent characteristics of coreceptor use and HIV type 1 V3 sequence in a large population of therapy-naive individuals.
AIDS research and human retroviruses 2008;24(2):219-28.
2007: Bernd Kupfer; Tobias Sing; Peter Schüffler; Rabea Hall; Ralf Kurz; Astrid McKeown; Karl-Eduard Schneweis; Wolfgang Eberl; Johannes Oldenburg; Hans H Brackmann; Jürgen K Rockstroh; Ulrich Spengler; Martin Däumer; Rolf Kaiser; Thomas Lengauer; Bertfried Matz
Fifteen years of env C2V3C3 evolution in six individuals infected clonally with human immunodeficiency virus type 1.
Journal of medical virology 2007;79(11):1629-39.
2007: Francesca Ceccherini-Silberstein; Valentina Svicher; Tobias Sing; Anna Artese; Maria Mercedes Santoro; Federica Forbici; Ada Bertoli; Stefano Alcaro; Guido Palamara; Antonella d'Arminio Monforte; Jan Balzarini; Andrea Antinori; Thomas Lengauer; Carlo Federico Perno
Characterization and structural analysis of novel mutations in human immunodeficiency virus type 1 reverse transcriptase involved in the regulation of resistance to nonnucleoside inhibitors.
Journal of virology 2007;81(20):11507-19.
2007: Andrew J Low; Winnie Dong; Dennison Chan; Tobias Sing; Ronald Swanstrom; Mark Jensen; Satish Pillai; Benjamin Good; P Richard Harrigan
Current V3 genotyping algorithms are inadequate for predicting X4 co-receptor usage in clinical isolates.
AIDS (London, England) 2007;21(14):F17-24.
2007: Oliver Sander; Tobias Sing; Ingolf Sommer; Andrew J Low; Peter K Cheung; P Richard Harrigan; Thomas Lengauer; Francisco S Domingues
Structural descriptors of gp120 V3 loop for the prediction of HIV-1 coreceptor usage.
PLoS computational biology 2007;3(3):e58.
2007: Katharina Skrabal; Andrew J Low; Winnie Dong; Tobias Sing; Peter K Cheung; Fabrizio Mammano; P Richard Harrigan
Determining human immunodeficiency virus coreceptor use in a clinical setting: degree of correlation between two phenotypic assays and a bioinformatic model.
Journal of clinical microbiology 2007;45(2):279-84.
2007: Tobias Sing; Andrew J Low; Niko Beerenwinkel; Oliver Sander; Peter K Cheung; Francisco S Domingues; Joachim Büch; Martin Däumer; Rolf Kaiser; Thomas Lengauer; P Richard Harrigan
Predicting HIV coreceptor usage on the basis of genetic and clinical covariates.
Antiviral therapy 2007;12(7):1097-106.
2007: Andre Altmann; Niko Beerenwinkel; Tobias Sing; Igor Savenkov; Martin Doumer; Rolf Kaiser; Soo-Yon Rhee; W Jeffrey Fessel; Robert W Shafer; Thomas Lengauer
Improved prediction of response to antiretroviral combination therapy using the genetic barrier to drug resistance.
Antiviral therapy 2007;12(2):169-78.
2006: Clara Lehmann; Martin Däumer; Ibrahim Boussaad; Tobias Sing; Niko Beerenwinkel; Thomas Lengauer; Norbert Schmeisser; Christoph Wyen; Gerd Fätkenheuer; Rolf Kaiser
Stable coreceptor usage of HIV in patients with ongoing treatment failure on HAART.
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology 2006;37(4):300-4.
2006: Valentina Svicher; Tobias Sing; Maria Mercedes Santoro; Federica Forbici; Fátima Rodríguez-Barrios; Ada Bertoli; Niko Beerenwinkel; Maria Concetta Bellocchi; Federico Gago; Antonella d'Arminio Monforte; Andrea Antinori; Thomas Lengauer; Francesca Ceccherini-Silberstein; Carlo Federico Perno
Involvement of novel human immunodeficiency virus type 1 reverse transcriptase mutations in the regulation of resistance to nucleoside inhibitors.
Journal of virology 2006;80(14):7186-98.
2006: Jens Verheyen; Elena Litau; Tobias Sing; Martin Däumer; Melanie Balduin; Mark Oette; Gerd Fätkenheuer; Jürgen K Rockstroh; Ulrike Schuldenzucker; Daniel Hoffmann; Herbert Pfister; Rolf Kaiser
Compensatory mutations at the HIV cleavage sites p7/p1 and p1/p6-gag in therapy-naive and therapy-experienced patients.
Antiviral therapy 2006;11(7):879-87.
2005: Niko Beerenwinkel; Tobias Sing; Thomas Lengauer; Jörg Rahnenführer; Kirsten Roomp; Igor Savenkov; Roman Fischer; Daniel Hoffmann; Joachim Selbig; Klaus Korn; Hauke Walter; Thomas Berg; Patrick Braun; Gerd Fätkenheuer; Mark Oette; Jürgen Rockstroh; Bernd Kupfer; Rolf Kaiser; Martin Däumer
Computational methods for the design of effective therapies against drug resistant HIV strains.
Bioinformatics (Oxford, England) 2005;21(21):3943-50.
2005: Tobias Sing; Oliver Sander; Niko Beerenwinkel; Thomas Lengauer
ROCR: visualizing classifier performance in R.
Bioinformatics (Oxford, England) 2005;21(20):3940-1.
2005: Niko Beerenwinkel; Martin Däumer; Tobias Sing; Jörg Rahnenführer; Thomas Lengauer; Joachim Selbig; Daniel Hoffmann; Rolf Kaiser
Estimating HIV evolutionary pathways and the genetic barrier to drug resistance.
The Journal of infectious diseases 2005;191(11):1953-60.