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Robert Singer

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Chemicals & Drugs

Anatomy

Physiology

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Procedures

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Molecular Sequence Data

Phenomena

Nucleic Acid Hybridization

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Saccharomyces cerevisiae

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Co-Publications
Name
21
Shenoy, Shailesh
18
Bassell, Gary
16
Condeelis, John
12
Darzacq, Xavier
11
Lawrence, Jeanne
11
Shav-Tal, Yaron
9
Gu, Wei
9
Hüttelmaier, Stefan
8
Long, Roy
8
Zenklusen, Daniel
7
Oleynikov, Yuri
7
Kislauskis, Edward
7
Chartrand, Pascal
6
Bertrand, Edouard
5
Levsky, Jeffrey M.

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Publications

TOP 3
Larson Daniel R; Singer Robert H; Zenklusen Daniel
A single molecule view of gene expression.
Gu Wei; Pan Feng; Singer Robert H
Blocking beta-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells.
Dib Amel; Glebov Oleg K; Shou Yaping; Singer Robert H; Kuehl W Michael
A der(8)t(8;11) chromosome in the Karpas-620 myeloma cell line expresses only cyclin D1: yet both cyclin D1 and MYC are repositioned in close proximity to the 3'IGH enhancer.

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All Publications

2009: Larson Daniel R; Singer Robert H; Zenklusen Daniel
A single molecule view of gene expression.
Trends in cell biology 2009;19(11):630-7.
2009: Gu Wei; Pan Feng; Singer Robert H
Blocking beta-catenin binding to the ZBP1 promoter represses ZBP1 expression, leading to increased proliferation and migration of metastatic breast-cancer cells.
Journal of cell science 2009;122(Pt 11):1895-905.
2009: Dib Amel; Glebov Oleg K; Shou Yaping; Singer Robert H; Kuehl W Michael
A der(8)t(8;11) chromosome in the Karpas-620 myeloma cell line expresses only cyclin D1: yet both cyclin D1 and MYC are repositioned in close proximity to the 3'IGH enhancer.
DNA repair 2009;8(3):330-5.
2009: Maier Sandra; Daroqui M Cecilia; Scherer Stefan; Roepcke Stefan; Velcich Anna; Shenoy Shailesh M; Singer Robert H; Augenlicht Leonard H
Butyrate and vitamin D3 induce transcriptional attenuation at the cyclin D1 locus in colonic carcinoma cells.
Journal of cellular physiology 2009;218(3):638-42.
2009: Darzacq Xavier; Yao Jie; Larson Daniel R; Causse Sébastien Z; Bosanac Lana; de Turris Valeria; Ruda Vera M; Lionnet Timothee; Zenklusen Daniel; Guglielmi Benjamin; Tjian Robert; Singer Robert H
Imaging transcription in living cells.
Annual review of biophysics 2009;38():173-96.
2008: Zenklusen Daniel; Larson Daniel R; Singer Robert H
Single-RNA counting reveals alternative modes of gene expression in yeast.
Nature structural & molecular biology 2008;15(12):1263-71.
2008: Aizer Adva; Brody Yehuda; Ler Lian Wee; Sonenberg Nahum; Singer Robert H; Shav-Tal Yaron
The dynamics of mammalian P body transport, assembly, and disassembly in vivo.
Molecular biology of the cell 2008;19(10):4154-66.
2008: Singer Robert H
Highways for mRNA transport.
Cell 2008;134(5):722-3.
2008: Vainer G; Vainer-Mosse E; Pikarsky A; Shenoy S M; Oberman F; Yeffet A; Singer R H; Pikarsky E; Yisraeli J K
A role for VICKZ proteins in the progression of colorectal carcinomas: regulating lamellipodia formation.
The Journal of pathology 2008;215(4):445-56.
2008: Gu Wei; Wells Amber L; Pan Feng; Singer Robert H
Feedback regulation between zipcode binding protein 1 and beta-catenin mRNAs in breast cancer cells.
Molecular and cellular biology 2008;28(16):4963-74.
2008: Pezo Rossanna C; Singer Robert H
Nuclear microenvironment in cancer diagnosis and treatment.
Journal of cellular biochemistry 2008;104(6):1953-63.
2008: Pezo Rossanna C; Gandhi Saumil J; Shirley L Andrew; Pestell Richard G; Augenlicht Leonard H; Singer Robert H
Single-cell transcription site activation predicts chemotherapy response in human colorectal tumors.
Cancer research 2008;68(13):4977-82.
2008: Dictenberg Jason B; Swanger Sharon A; Antar Laura N; Singer Robert H; Bassell Gary J
A direct role for FMRP in activity-dependent dendritic mRNA transport links filopodial-spine morphogenesis to fragile X syndrome.
Developmental cell 2008;14(6):926-39.
2008: Darzacq Xavier; Singer Robert H
The dynamic range of transcription.
Molecular cell 2008;30(5):545-6.
2008: Deng Yingfeng; Singer Robert H; Gu Wei
Translation of ASH1 mRNA is repressed by Puf6p-Fun12p/eIF5B interaction and released by CK2 phosphorylation.
Genes & development 2008;22(8):1037-50.
2008: Rodriguez Alexis J; Czaplinski Kevin; Condeelis John S; Singer Robert H
Mechanisms and cellular roles of local protein synthesis in mammalian cells.
Current opinion in cell biology 2008;20(2):144-9.
2008: Chang Wakam; Zaarour Rania F; Reck-Peterson Samara; Rinn John; Singer Robert H; Snyder Michael; Novick Peter; Mooseker Mark S
Myo2p, a class V myosin in budding yeast, associates with a large ribonucleic acid-protein complex that contains mRNAs and subunits of the RNA-processing body.
RNA (New York, N.Y.) 2008;14(3):491-502.
2008: Chao Jeffrey A; Patskovsky Yury; Almo Steven C; Singer Robert H
Structural basis for the coevolution of a viral RNA-protein complex.
Nature structural & molecular biology 2008;15(1):103-5.
2008: Grünwald David; Singer Robert H; Czaplinski Kevin
Cell biology of mRNA decay.
Methods in enzymology 2008;448():553-77.
2008: Grünwald David; Shenoy Shailesh M; Burke Sean; Singer Robert H
Calibrating excitation light fluxes for quantitative light microscopy in cell biology.
Nature protocols 2008;3(11):1809-14.
2007: Pan Feng; Hüttelmaier Stefan; Singer Robert H; Gu Wei
ZBP2 facilitates binding of ZBP1 to beta-actin mRNA during transcription.
Molecular and cellular biology 2007;27(23):8340-51.
2007: Levsky Jeffrey M; Shenoy Shailesh M; Chubb Jonathan R; Hall Charles B; Capodieci Paola; Singer Robert H
The spatial order of transcription in mammalian cells.
Journal of cellular biochemistry 2007;102(3):609-17.
2007: Lapidus Kyle; Wyckoff Jeffrey; Mouneimne Ghassan; Lorenz Mike; Soon Lillian; Condeelis John S; Singer Robert H
ZBP1 enhances cell polarity and reduces chemotaxis.
Journal of cell science 2007;120(Pt 18):3173-8.
2007: Darzacq Xavier; Shav-Tal Yaron; de Turris Valeria; Brody Yehuda; Shenoy Shailesh M; Phair Robert D; Singer Robert H
In vivo dynamics of RNA polymerase II transcription.
Nature structural & molecular biology 2007;14(9):796-806.
2007: Zhang Honglai; Xing Lei; Singer Robert H; Bassell Gary J
QNQKE targeting motif for the SMN-Gemin multiprotein complexin neurons.
Journal of neuroscience research 2007;85(12):2657-67.
2007: Rodriguez Alexis J; Condeelis John; Singer Robert H; Dictenberg Jason B
Imaging mRNA movement from transcription sites to translation sites.
Seminars in cell & developmental biology 2007;18(2):202-8.
2007: Dong Shuyun; Li Chunfang; Zenklusen Daniel; Singer Robert H; Jacobson Allan; He Feng
YRA1 autoregulation requires nuclear export and cytoplasmic Edc3p-mediated degradation of its pre-mRNA.
Molecular cell 2007;25(4):559-73.
2007: Garcia M; Darzacq X; Delaveau T; Jourdren L; Singer R H; Jacq C
Mitochondria-associated yeast mRNAs and the biogenesis of molecular complexes.
Molecular biology of the cell 2007;18(2):362-8.
2007: Garcia Mathilde; Darzacq Xavier; Devaux Frederic; Singer Robert H; Jacq Claude
Yeast mitochondrial transcriptomics.
Methods in molecular biology (Clifton, N.J.) 2007;372():505-28.
2007: Loudig Olivier; Milova Ekaterina; Brandwein-Gensler Margaret; Massimi Aldo; Belbin Thomas J; Childs Geoffrey; Singer Robert H; Rohan Thomas; Prystowsky Michael B
Molecular restoration of archived transcriptional profiles by complementary-template reverse-transcription (CT-RT).
Nucleic acids research 2007;35(15):e94.
2006: Kittur Nupur; Darzacq Xavier; Roy Sujayita; Singer Robert H; Meier U Thomas
Dynamic association and localization of human H/ACA RNP proteins.
RNA (New York, N.Y.) 2006;12(12):2057-62.
2006: Czaplinski Kevin; Singer Robert H
Pathways for mRNA localization in the cytoplasm.
Trends in biochemical sciences 2006;31(12):687-93.
2006: Stöhr Nadine; Lederer Marcell; Reinke Claudia; Meyer Sylke; Hatzfeld Mechthild; Singer Robert H; Hüttelmaier Stefan
ZBP1 regulates mRNA stability during cellular stress.
The Journal of cell biology 2006;175(4):527-34.
2006: Rodriguez Alexis J; Shenoy Shailesh M; Singer Robert H; Condeelis John
Visualization of mRNA translation in living cells.
The Journal of cell biology 2006;175(1):67-76.
2006: Rideau Alexis P; Gooding Clare; Simpson Peter J; Monie Tom P; Lorenz Mike; Hüttelmaier Stefan; Singer Robert H; Matthews Stephen; Curry Stephen; Smith Christopher W J
A peptide motif in Raver1 mediates splicing repression by interaction with the PTB RRM2 domain.
Nature structural & molecular biology 2006;13(9):839-48.
2006: Zhang Honglai; Xing Lei; Rossoll Wilfried; Wichterle Hynek; Singer Robert H; Bassell Gary J
Multiprotein complexes of the survival of motor neuron protein SMN with Gemins traffic to neuronal processes and growth cones of motor neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(33):8622-32.
2006: Shav-Tal Yaron; Darzacq Xavier; Singer Robert H
Gene expression within a dynamic nuclear landscape.
The EMBO journal 2006;25(15):3469-79.
2006: Chubb Jonathan R; Trcek Tatjana; Shenoy Shailesh M; Singer Robert H
Transcriptional pulsing of a developmental gene.
Current biology : CB 2006;16(10):1018-25.
2006: Darzacq Xavier; Kittur Nupur; Roy Sujayita; Shav-Tal Yaron; Singer Robert H; Meier U Thomas
Stepwise RNP assembly at the site of H/ACA RNA transcription in human cells.
The Journal of cell biology 2006;173(2):207-18.
2006: Chubb Jonathan R; Bloomfield Gareth; Xu Qikai; Kaller Markus; Ivens Al; Skelton Jason; Turner Bryan M; Nellen Wolfgang; Shaulsky Gad; Kay Robert R; Bickmore Wendy A; Singer Robert H
Developmental timing in Dictyostelium is regulated by the Set1 histone methyltransferase.
Developmental biology 2006;292(2):519-32.
2006: Chang Lynne; Shav-Tal Yaron; Trcek Tatjana; Singer Robert H; Goldman Robert D
Assembling an intermediate filament network by dynamic cotranslation.
The Journal of cell biology 2006;172(5):747-58.
2005: Hüttelmaier Stefan; Zenklusen Daniel; Lederer Marcell; Dictenberg Jason; Lorenz Mike; Meng Xiuhua; Bassell Gary J; Condeelis John; Singer Robert H
Spatial regulation of beta-actin translation by Src-dependent phosphorylation of ZBP1.
Nature 2005;438(7067):512-5.
2005: Singer Robert H; Lawrence David S; Ovryn Ben; Condeelis John
Imaging of gene expression in living cells and tissues.
Journal of biomedical optics 2005;10(5):051406.
2005: Shav-Tal Yaron; Singer Robert H
RNA localization.
Journal of cell science 2005;118(Pt 18):4077-81.
2005: Capodieci Paola; Donovan Michael; Buchinsky Heidi; Jeffers Yusuf; Cordon-Cardo Carlos; Gerald William; Edelson Jon; Shenoy Shailesh M; Singer Robert H
Gene expression profiling in single cells within tissue.
Nature methods 2005;2(9):663-5.
2005: Mingle Lisa A; Okuhama Nataly N; Shi Jian; Singer Robert H; Condeelis John; Liu Gang
Localization of all seven messenger RNAs for the actin-polymerization nucleator Arp2/3 complex in the protrusions of fibroblasts.
Journal of cell science 2005;118(Pt 11):2425-33.
2005: Darzacq Xavier; Singer Robert H; Shav-Tal Yaron
Dynamics of transcription and mRNA export.
Current opinion in cell biology 2005;17(3):332-9.
2005: Faul Christian; Hüttelmaier Stefan; Oh Jun; Hachet Virginie; Singer Robert H; Mundel Peter
Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3.
The Journal of cell biology 2005;169(3):415-24.
2005: Shav-Tal Yaron; Blechman Janna; Darzacq Xavier; Montagna Cristina; Dye Billy T; Patton James G; Singer Robert H; Zipori Dov
Dynamic sorting of nuclear components into distinct nucleolar caps during transcriptional inhibition.
Molecular biology of the cell 2005;16(5):2395-413.
2005: Condeelis John; Singer Robert H
How and why does beta-actin mRNA target?
Biology of the cell / under the auspices of the European Cell Biology Organization 2005;97(1):97-110.
2005: Condeelis John; Singer Robert H; Segall Jeffrey E
The great escape: when cancer cells hijack the genes for chemotaxis and motility.
Annual review of cell and developmental biology 2005;21():695-718.
2004: Wang Weigang; Goswami Sumanta; Lapidus Kyle; Wells Amber L; Wyckoff Jeffrey B; Sahai Erik; Singer Robert H; Segall Jeffrey E; Condeelis John S
Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors.
Cancer research 2004;64(23):8585-94.
2004: Niessing Dierk; Hüttelmaier Stefan; Zenklusen Daniel; Singer Robert H; Burley Stephen K
She2p is a novel RNA binding protein with a basic helical hairpin motif.
Cell 2004;119(4):491-502.
2004: Shav-Tal Yaron; Singer Robert H; Darzacq Xavier
Imaging gene expression in single living cells.
Nature reviews. Molecular cell biology 2004;5(10):855-61.
2004: Shav-Tal Yaron; Darzacq Xavier; Shenoy Shailesh M; Fusco Dahlene; Janicki Susan M; Spector David L; Singer Robert H
Dynamics of single mRNPs in nuclei of living cells.
Science (New York, N.Y.) 2004;304(5678):1797-800.
2004: Gu Wei; Deng Yingfeng; Zenklusen Daniel; Singer Robert H
A new yeast PUF family protein, Puf6p, represses ASH1 mRNA translation and is required for its localization.
Genes & development 2004;18(12):1452-65.
2004: Lorenz Mike; Yamaguchi Hideki; Wang Yarong; Singer Robert H; Condeelis John
Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells.
Current biology : CB 2004;14(8):697-703.
2004: Lorenz Mike; DesMarais Vera; Macaluso Frank; Singer Robert H; Condeelis John
Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation.
Cell motility and the cytoskeleton 2004;57(4):207-17.
2004: Janicki Susan M; Tsukamoto Toshiro; Salghetti Simone E; Tansey William P; Sachidanandam Ravi; Prasanth Kannanganattu V; Ried Thomas; Shav-Tal Yaron; Bertrand Edouard; Singer Robert H; Spector David L
From silencing to gene expression: real-time analysis in single cells.
Cell 2004;116(5):683-98.
2004: Fusco Dahlene; Bertrand Edouard; Singer Robert H
Imaging of single mRNAs in the cytoplasm of living cells.
Progress in molecular and subcellular biology 2004;35():135-50.
2003: Darzacq Xavier; Powrie Erin; Gu Wei; Singer Robert H; Zenklusen Daniel
RNA asymmetric distribution and daughter/mother differentiation in yeast.
Current opinion in microbiology 2003;6(6):614-20.
2003: Gromak Natalia; Rideau Alexis; Southby Justine; Scadden A D J; Gooding Clare; Hüttelmaier Stefan; Singer Robert H; Smith Christopher W J
The PTB interacting protein raver1 regulates alpha-tropomyosin alternative splicing.
The EMBO journal 2003;22(23):6356-64.
2003: Eom Taesun; Antar Laura N; Singer Robert H; Bassell Gary J
Localization of a beta-actin messenger ribonucleoprotein complex with zipcode-binding protein modulates the density of dendritic filopodia and filopodial synapses.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(32):10433-44.
2003: Singer Robert H
RNA localization: visualization in real-time.
Current biology : CB 2003;13(17):R673-5.
2003: Matthiesen Steen H; Shenoy Shailesh M; Kim Kami; Singer Robert H; Satir Birgit H
Role of the parafusin orthologue, PRP1, in microneme exocytosis and cell invasion in Toxoplasma gondii.
Cellular microbiology 2003;5(9):613-24.
2003: Zhang Honglai L; Pan Feng; Hong Daewha; Shenoy Shailesh M; Singer Robert H; Bassell Gary J
Active transport of the survival motor neuron protein and the role of exon-7 in cytoplasmic localization.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(16):6627-37.
2003: Levsky Jeffrey M; Singer Robert H
Fluorescence in situ hybridization: past, present and future.
Journal of cell science 2003;116(Pt 14):2833-8.
2003: Colón-Ramos Daniel A; Salisbury Jeffrey L; Sanders Mark A; Shenoy Shailesh M; Singer Robert H; García-Blanco Mariano A
Asymmetric distribution of nuclear pore complexes and the cytoplasmic localization of beta2-tubulin mRNA in Chlamydomonas reinhardtii.
Developmental cell 2003;4(6):941-52.
2003: Tiruchinapalli Dhanrajan M; Oleynikov Yuri; Kelic Sofija; Shenoy Shailesh M; Hartley Adam; Stanton Patric K; Singer Robert H; Bassell Gary J
Activity-dependent trafficking and dynamic localization of zipcode binding protein 1 and beta-actin mRNA in dendrites and spines of hippocampal neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(8):3251-61.
2003: Oleynikov Yuri; Singer Robert H
Real-time visualization of ZBP1 association with beta-actin mRNA during transcription and localization.
Current biology : CB 2003;13(3):199-207.
2003: Fusco Dahlene; Accornero Nathalie; Lavoie Brigitte; Shenoy Shailesh M; Blanchard Jean Marie; Singer Robert H; Bertrand Edouard
Single mRNA molecules demonstrate probabilistic movement in living mammalian cells.
Current biology : CB 2003;13(2):161-7.
2003: Farina Kim L; Huttelmaier Stefan; Musunuru Kiran; Darnell Robert; Singer Robert H
Two ZBP1 KH domains facilitate beta-actin mRNA localization, granule formation, and cytoskeletal attachment.
The Journal of cell biology 2003;160(1):77-87.
2003: Levsky Jeffrey M; Singer Robert H
Gene expression and the myth of the average cell.
Trends in cell biology 2003;13(1):4-6.
2003: Femino Andrea M; Fogarty Kevin; Lifshitz Lawrence M; Carrington Walter; Singer Robert H
Visualization of single molecules of mRNA in situ.
Methods in enzymology 2003;361():245-304.
2002: Chartrand Pascal; Meng Xiu Hua; Huttelmaier Stefan; Donato Damiane; Singer Robert H
Asymmetric sorting of ash1p in yeast results from inhibition of translation by localization elements in the mRNA.
Molecular cell 2002;10(6):1319-30.
2002: Wang Weigang; Wyckoff Jeffrey B; Frohlich Victoria Centonze; Oleynikov Yuri; Hüttelmaier Stefan; Zavadil Jiri; Cermak Lukas; Bottinger Erwin P; Singer Robert H; White John G; Segall Jeffrey E; Condeelis John S
Single cell behavior in metastatic primary mammary tumors correlated with gene expression patterns revealed by molecular profiling.
Cancer research 2002;62(21):6278-88.
2002: Wilson Andrew J; Velcich Anna; Arango Diego; Kurland Amy R; Shenoy Shailesh M; Pezo Rossanna C; Levsky Jeffrey M; Singer Robert H; Augenlicht Leonard H
Novel detection and differential utilization of a c-myc transcriptional block in colon cancer chemoprevention.
Cancer research 2002;62(21):6006-10.
2002: Farina Kim L; Singer Robert H
The nuclear connection in RNA transport and localization.
Trends in cell biology 2002;12(10):466-72.
2002: Srisawat Chatchawan; Houser-Scott Felicia; Bertrand Edouard; Xiao Shaohua; Singer Robert H; Engelke David R
An active precursor in assembly of yeast nuclear ribonuclease P.
RNA (New York, N.Y.) 2002;8(10):1348-60.
2002: Levsky Jeffrey M; Shenoy Shailesh M; Pezo Rossanna C; Singer Robert H
Single-cell gene expression profiling.
Science (New York, N.Y.) 2002;297(5582):836-40.
2002: Liu Gang; Grant Wayne M; Persky Daniel; Latham Vaughan M; Singer Robert H; Condeelis John
Interactions of elongation factor 1alpha with F-actin and beta-actin mRNA: implications for anchoring mRNA in cell protrusions.
Molecular biology of the cell 2002;13(2):579-92.
2002: Gu Wei; Pan Feng; Zhang Honglai; Bassell Gary J; Singer Robert H
A predominantly nuclear protein affecting cytoplasmic localization of beta-actin mRNA in fibroblasts and neurons.
The Journal of cell biology 2002;156(1):41-51.
2001: Matthiesen S H; Shenoy S M; Kim K; Singer R H; Satir B H
A parafusin-related Toxoplasma protein in Ca2+-regulated secretory organelles.
European journal of cell biology 2001;80(12):775-83.
2001: Hüttelmaier S; Illenberger S; Grosheva I; Rüdiger M; Singer R H; Jockusch B M
Raver1, a dual compartment protein, is a ligand for PTB/hnRNPI and microfilament attachment proteins.
The Journal of cell biology 2001;155(5):775-86.
2001: Zhang H L; Eom T; Oleynikov Y; Shenoy S M; Liebelt D A; Dictenberg J B; Singer R H; Bassell G J
Neurotrophin-induced transport of a beta-actin mRNP complex increases beta-actin levels and stimulates growth cone motility.
Neuron 2001;31(2):261-75.
2001: Latham V M; Yu E H; Tullio A N; Adelstein R S; Singer R H
A Rho-dependent signaling pathway operating through myosin localizes beta-actin mRNA in fibroblasts.
Current biology : CB 2001;11(13):1010-6.
2001: Gwizdek C; Bertrand E; Dargemont C; Lefebvre J C; Blanchard J M; Singer R H; Doglio A
Terminal minihelix, a novel RNA motif that directs polymerase III transcripts to the cell cytoplasm. Terminal minihelix and RNA export.
The Journal of biological chemistry 2001;276(28):25910-8.
2001: Shestakova E A; Singer R H; Condeelis J
The physiological significance of beta -actin mRNA localization in determining cell polarity and directional motility.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(13):7045-50.
2001: Long R M; Gu W; Meng X; Gonsalvez G; Singer R H; Chartrand P
An exclusively nuclear RNA-binding protein affects asymmetric localization of ASH1 mRNA and Ash1p in yeast.
The Journal of cell biology 2001;153(2):307-18.
2001: Fan Y; Braut S A; Lin Q; Singer R H; Skoultchi A I
Determination of transgenic loci by expression FISH.
Genomics 2001;71(1):66-9.
2001: Chartrand P; Singer R H; Long R M
RNP localization and transport in yeast.
Annual review of cell and developmental biology 2001;17():297-310.
2001: Bassell G J; Singer R H
Neuronal RNA localization and the cytoskeleton.
Results and problems in cell differentiation 2001;34():41-56.
2000: Vilardell J; Chartrand P; Singer R H; Warner J R
The odyssey of a regulated transcript.
RNA (New York, N.Y.) 2000;6(12):1773-80.
2000: Long R M; Gu W; Lorimer E; Singer R H; Chartrand P
She2p is a novel RNA-binding protein that recruits the Myo4p-She3p complex to ASH1 mRNA.
The EMBO journal 2000;19(23):6592-601.
2000: Kendall A; Hull M W; Bertrand E; Good P D; Singer R H; Engelke D R
A CBF5 mutation that disrupts nucleolar localization of early tRNA biosynthesis in yeast also suppresses tRNA gene-mediated transcriptional silencing.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(24):13108-13.
2000: Pereira M C; Singer R H; de Meirelles M N
Trypanosoma cruzi infection affects actin mRNA regulation in heart muscle cells.
The Journal of eukaryotic microbiology 2000;47(3):271-9.
2000: Pereira M C; Singer R H; de Meirelles M N
Ultrastructural distribution of poly (A)+ RNA during Trypanosoma cruzi-cardiomyocyte interaction in vitro: a quantitative analysis of the total mRNA content by in situ hybridization.
The Journal of eukaryotic microbiology 2000;47(3):264-70.
2000: Chartrand P; Bertrand E; Singer R H; Long R M
Sensitive and high-resolution detection of RNA in situ.
Methods in enzymology 2000;318():493-506.
1999: Zhang H L; Singer R H; Bassell G J
Neurotrophin regulation of beta-actin mRNA and protein localization within growth cones.
The Journal of cell biology 1999;147(1):59-70.
1999: Politz J C; Singer R H
In situ reverse transcription for detection of hybridization between oligonucleotides and their intracellular targets.
Methods (San Diego, Calif.) 1999;18(3):281-5.
1999: Samarsky D A; Ferbeyre G; Bertrand E; Singer R H; Cedergren R; Fournier M J
A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiency.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(12):6609-14.
1999: Greenberg R A; Chin L; Femino A; Lee K H; Gottlieb G J; Singer R H; Greider C W; DePinho R A
Short dysfunctional telomeres impair tumorigenesis in the INK4a(delta2/3) cancer-prone mouse.
Cell 1999;97(4):515-25.
1999: Chartrand P; Meng X H; Singer R H; Long R M
Structural elements required for the localization of ASH1 mRNA and of a green fluorescent protein reporter particle in vivo.
Current biology : CB 1999;9(6):333-6.
1999: Politz J C; Tuft R A; Pederson T; Singer R H
Movement of nuclear poly(A) RNA throughout the interchromatin space in living cells.
Current biology : CB 1999;9(6):285-91.
1999: Shestakova E A; Wyckoff J; Jones J; Singer R H; Condeelis J
Correlation of beta-actin messenger RNA localization with metastatic potential in rat adenocarcinoma cell lines.
Cancer research 1999;59(6):1202-5.
1999: Bassell G J; Oleynikov Y; Singer R H
The travels of mRNAs through all cells large and small.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1999;13(3):447-54.
1999: Meirelles M N; Pereira M C; Singer R H; Soeiro M N; Garzoni L R; Silva D T; Barbosa H S; Araujo-Jorge T C; Masuda M O; Capella M A; Lopes A G; Vermelho A B
Trypanosoma cruzi-cardiomyocytes: new contributions regarding a better understanding of this interaction.
Memórias do Instituto Oswaldo Cruz 1999;94 Suppl 1():149-52.
1998: Barcellini-Couget S; Fenard D; Bertrand E; Singer R H; Lefebvre J C; Doglio A
3'-End modification of the adenoviral VA1 gene affects its expression in human cells: consequences for the design of chimeric VA1 RNA ribozymes.
Antisense & nucleic acid drug development 1998;8(5):379-90.
1998: Bertrand E; Chartrand P; Schaefer M; Shenoy S M; Singer R H; Long R M
Localization of ASH1 mRNA particles in living yeast.
Molecular cell 1998;2(4):437-45.
1998: Oleynikov Y; Singer R H
RNA localization: different zipcodes, same postman?
Trends in cell biology 1998;8(10):381-3.
1998: Bertrand E; Houser-Scott F; Kendall A; Singer R H; Engelke D R
Nucleolar localization of early tRNA processing.
Genes & development 1998;12(16):2463-8.
1998: Samarsky D A; Fournier M J; Singer R H; Bertrand E
The snoRNA box C/D motif directs nucleolar targeting and also couples snoRNA synthesis and localization.
The EMBO journal 1998;17(13):3747-57.
1998: Singer R H
Triplet-repeat transcripts: a role for DNA in disease.
Science (New York, N.Y.) 1998;280(5364):696-7.
1998: Chicurel M E; Singer R H; Meyer C J; Ingber D E
Integrin binding and mechanical tension induce movement of mRNA and ribosomes to focal adhesions.
Nature 1998;392(6677):730-3.
1998: Femino A M; Fay F S; Fogarty K; Singer R H
Visualization of single RNA transcripts in situ.
Science (New York, N.Y.) 1998;280(5363):585-90.
1998: Bassell G J; Zhang H; Byrd A L; Femino A M; Singer R H; Taneja K L; Lifshitz L M; Herman I M; Kosik K S
Sorting of beta-actin mRNA and protein to neurites and growth cones in culture.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(1):251-65.
1997: Singer R H; Green M R
Compartmentalization of eukaryotic gene expression: causes and effects.
Cell 1997;91(3):291-4.
1997: Long R M; Singer R H; Meng X; Gonzalez I; Nasmyth K; Jansen R P
Mating type switching in yeast controlled by asymmetric localization of ASH1 mRNA.
Science (New York, N.Y.) 1997;277(5324):383-7.
1997: Davis B M; McCurrach M E; Taneja K L; Singer R H; Housman D E
Expansion of a CUG trinucleotide repeat in the 3' untranslated region of myotonic dystrophy protein kinase transcripts results in nuclear retention of transcripts.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7388-93.
1997: Jacobson M R; Cao L G; Taneja K; Singer R H; Wang Y L; Pederson T
Nuclear domains of the RNA subunit of RNase P.
Journal of cell science 1997;110 ( Pt 7)():829-37.
1997: Ross A F; Oleynikov Y; Kislauskis E H; Taneja K L; Singer R H
Characterization of a beta-actin mRNA zipcode-binding protein.
Molecular and cellular biology 1997;17(4):2158-65.
1997: Kislauskis E H; Zhu X; Singer R H
beta-Actin messenger RNA localization and protein synthesis augment cell motility.
The Journal of cell biology 1997;136(6):1263-70.
1997: Fay F S; Taneja K L; Shenoy S; Lifshitz L; Singer R H
Quantitative digital analysis of diffuse and concentrated nuclear distributions of nascent transcripts, SC35 and poly(A).
Experimental cell research 1997;231(1):27-37.
1997: Bassell G; Singer R H
mRNA and cytoskeletal filaments.
Current opinion in cell biology 1997;9(1):109-15.
1996: Singer R H
RNA: traffic report.
Trends in cell biology 1996;6(12):486-9.
1996: Mathijs J M; Shenoy S M; Singer R H
Human immunodeficiency virus detection in lymph nodes by image analysis of in situ hybridization: basis of a diagnostic test for cadaveric donors.
Transplantation proceedings 1996;28(5):2945-9.
1996: Singer R H
Triplet repeats and human disease.
Molecular medicine today 1996;2(2):65-9.
1995: Long R M; Elliott D J; Stutz F; Rosbash M; Singer R H
Spatial consequences of defective processing of specific yeast mRNAs revealed by fluorescent in situ hybridization.
RNA (New York, N.Y.) 1995;1(10):1071-8.
1995: Politz J C; Taneja K L; Singer R H
Characterization of hybridization between synthetic oligodeoxynucleotides and RNA in living cells.
Nucleic acids research 1995;23(24):4946-53.
1995: Taneja K L; McCurrach M; Schalling M; Housman D; Singer R H
Foci of trinucleotide repeat transcripts in nuclei of myotonic dystrophy cells and tissues.
The Journal of cell biology 1995;128(6):995-1002.
1994: Zhang G; Taneja K L; Singer R H; Green M R
Localization of pre-mRNA splicing in mammalian nuclei.
Nature 1994;372(6508):809-12.
1994: Kislauskis E H; Zhu X; Singer R H
Sequences responsible for intracellular localization of beta-actin messenger RNA also affect cell phenotype.
The Journal of cell biology 1994;127(2):441-51.
1994: Somasundaran M; Zapp M L; Beattie L K; Pang L; Byron K S; Bassell G J; Sullivan J L; Singer R H
Localization of HIV RNA in mitochondria of infected cells: potential role in cytopathogenicity.
The Journal of cell biology 1994;126(6):1353-60.
1994: Latham V M; Kislauskis E H; Singer R H; Ross A F
Beta-actin mRNA localization is regulated by signal transduction mechanisms.
The Journal of cell biology 1994;126(5):1211-9.
1994: Bassell G J; Powers C M; Taneja K L; Singer R H
Single mRNAs visualized by ultrastructural in situ hybridization are principally localized at actin filament intersections in fibroblasts.
The Journal of cell biology 1994;126(4):863-76.
1994: Bassell G J; Singer R H; Kosik K S
Association of poly(A) mRNA with microtubules in cultured neurons.
Neuron 1994;12(3):571-82.
1994: Bassell G J; Taneja K L; Kislauskis E H; Sundell C L; Powers C M; Ross A; Singer R H
Actin filaments and the spatial positioning of mRNAS.
Advances in experimental medicine and biology 1994;358():183-9.
1993: Rosbash M; Singer R H
RNA travel: tracks from DNA to cytoplasm.
Cell 1993;75(3):399-401.
1993: Singer R H
RNA zipcodes for cytoplasmic addresses.
Current biology : CB 1993;3(10):719-21.
1993: Kislauskis E H; Li Z; Singer R H; Taneja K L
Isoform-specific 3'-untranslated sequences sort alpha-cardiac and beta-cytoplasmic actin messenger RNAs to different cytoplasmic compartments.
The Journal of cell biology 1993;123(1):165-72.
1993: Pockwinse S M; Lawrence J B; Singer R H; Stein J L; Lian J B; Stein G S
Gene expression at single cell resolution associated with development of the bone cell phenotype: ultrastructural and in situ hybridization analysis.
Bone 1993;14(3):347-52.
1992: Kislauskis E H; Singer R H
Determinants of mRNA localization.
Current opinion in cell biology 1992;4(6):975-8.
1992: Taneja K L; Lifshitz L M; Fay F S; Singer R H
Poly(A) RNA codistribution with microfilaments: evaluation by in situ hybridization and quantitative digital imaging microscopy.
The Journal of cell biology 1992;119(5):1245-60.
1992: Singer R H
The cytoskeleton and mRNA localization.
Current opinion in cell biology 1992;4(1):15-9.
1991: Sundell C L; Singer R H
Requirement of microfilaments in sorting of actin messenger RNA.
Science (New York, N.Y.) 1991;253(5025):1275-7.
1991: Lawrence J B; Singer R H
Spatial organization of nucleic acid sequences within cells.
Seminars in cell biology 1991;2(2):83-101.
1991: McNeil J A; Johnson C V; Carter K C; Singer R H; Lawrence J B
Localizing DNA and RNA within nuclei and chromosomes by fluorescence in situ hybridization.
Genetic analysis, techniques and applications 1991;8(2):41-58.
1991: Pomeroy M E; Lawrence J B; Singer R H; Billings-Gagliardi S
Distribution of myosin heavy chain mRNA in embryonic muscle tissue visualized by ultrastructural in situ hybridization.
Developmental biology 1991;143(1):58-67.
1991: Johnson C V; Singer R H; Lawrence J B
Fluorescent detection of nuclear RNA and DNA: implications for genome organization.
Methods in cell biology 1991;35():73-99.
1990: Sundell C L; Singer R H
Actin mRNA localizes in the absence of protein synthesis.
The Journal of cell biology 1990;111(6 Pt 1):2397-403.
1990: Taneja K L; Singer R H
Detection and localization of actin mRNA isoforms in chicken muscle cells by in situ hybridization using biotinated oligonucleotide probes.
Journal of cellular biochemistry 1990;44(4):241-52.
1990: Lawrence J B; Singer R H; McNeil J A
Interphase and metaphase resolution of different distances within the human dystrophin gene.
Science (New York, N.Y.) 1990;249(4971):928-32.
1990: Lawrence J B; Marselle L M; Byron K S; Johnson C V; Sullivan J L; Singer R H
Subcellular localization of low-abundance human immunodeficiency virus nucleic acid sequences visualized by fluorescence in situ hybridization.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(14):5420-4.
1989: Takahashi E; Hori T; Lawrence J B; McNeil J; Singer R H; O'Connell P; Leppert M; White R
Human type II collagen gene (COL2A1) assigned to chromosome 12q13.1-q13.2 by in situ hybridization with biotinylated DNA probe.
Jinrui idengaku zasshi. The Japanese journal of human genetics 1989;34(4):307-11.
1989: Bashir R; Hochberg F; Singer R H
Detection of Epstein-Barr virus by in situ hybridization. Progress toward development of a nonisotopic diagnostic test.
The American journal of pathology 1989;135(6):1035-44.
1989: Singer R H; Byron K S; Lawrence J B; Sullivan J L
Detection of HIV-1-infected cells from patients using nonisotopic in situ hybridization.
Blood 1989;74(6):2295-301.
1989: Singer R H; Langevin G L; Lawrence J B
Ultrastructural visualization of cytoskeletal mRNAs and their associated proteins using double-label in situ hybridization.
The Journal of cell biology 1989;108(6):2343-53.
1989: Lawrence J B; Taneja K; Singer R H
Temporal resolution and sequential expression of muscle-specific genes revealed by in situ hybridization.
Developmental biology 1989;133(1):235-46.
1989: Lawrence J B; Singer R H; Marselle L M
Highly localized tracks of specific transcripts within interphase nuclei visualized by in situ hybridization.
Cell 1989;57(3):493-502.
1989: Singer R H; Lawrence J B; Silva F; Langevin G L; Pomeroy M; Billings-Gagliardi S
Strategies for ultrastructural visualization of biotinated probes hybridized to messenger RNA in situ.
Current topics in microbiology and immunology 1989;143():55-69.
1988: Lawrence J B; Singer R H; Villnave C A; Stein J L; Stein G S
Intracellular distribution of histone mRNAs in human fibroblasts studied by in situ hybridization.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(2):463-7.
1988: Lawrence J B; Villnave C A; Singer R H
Sensitive, high-resolution chromatin and chromosome mapping in situ: presence and orientation of two closely integrated copies of EBV in a lymphoma line.
Cell 1988;52(1):51-61.
1987: Taneja K; Singer R H
Use of oligodeoxynucleotide probes for quantitative in situ hybridization to actin mRNA.
Analytical biochemistry 1987;166(2):389-98.
1987: Moreland R B; Langevin G L; Singer R H; Garcea R L; Hereford L M
Amino acid sequences that determine the nuclear localization of yeast histone 2B.
Molecular and cellular biology 1987;7(11):4048-57.
1986: Lawrence J B; Singer R H
Intracellular localization of messenger RNAs for cytoskeletal proteins.
Cell 1986;45(3):407-15.
1985: Lawrence J B; Singer R H
Quantitative analysis of in situ hybridization methods for the detection of actin gene expression.
Nucleic acids research 1985;13(5):1777-99.
1984: Singer R H; Pudney J A
Filament-directed intercellular contacts during differentiation of cultured chick myoblasts.
Tissue & cell 1984;16(1):17-29.
1983: Oblas B; Boyd N D; Singer R H
Analysis of receptor-ligand interactions using nitrocellulose gel transfer: application to Torpedo acetylcholine receptor and alpha-bungarotoxin.
Analytical biochemistry 1983;130(1):1-8.
1982: Singer R H; Ward D C
Actin gene expression visualized in chicken muscle tissue culture by using in situ hybridization with a biotinated nucleotide analog.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(23):7331-5.
1981: Ettienne E M; Swartz K; Singer R H
Increased turnover of proteins from the sarcoplasmic reticulum of dystrophic chicken muscle cells in tissue culture.
The Journal of biological chemistry 1981;256(12):6408-12.
1981: Kabat-Zinn J; Singer R H
Sea urchin tube feet: unique structures that allow a cytological and molecular approach to the study of actin and its gene expression.
The Journal of cell biology 1981;89(1):109-14.
1980: Pudney J; Singer R H
Intracellular filament bundles in whole mounts of chick and human myoblasts extracted with triton X-100.
Tissue & cell 1980;12(4):595-612.
1979: Pudney J; Singer R H
Electron microscopic visualization of the filamentous reticulum in whole cultured presumptive chick myoblasts.
The American journal of anatomy 1979;156(3):321-36.
1978: Ettienne E M; Singer R H
Ca2+ binding, ATP-dependent Ca2+ transport, and total tissue Ca2+ in embryonic and adult avian dystrophic pectoralis.
The Journal of membrane biology 1978;44(3-4):195-210.
1978: Kessler-Icekson G; Singer R H; Yaffe D
The capacity of polyadenylated RNA from myogenic cells treated with actinomycin D to direct protein synthesis in a cell-free system.
European journal of biochemistry / FEBS 1978;88(2):403-10.
1978: Singer R H; Kessler-Icekson G
Stability of polyadenylated RNA in differentiating myogenic cells.
European journal of biochemistry / FEBS 1978;88(2):395-402.
1978: Huang H L; Singer R H; Lazarides E
Actin-containing microprocesses in the fusion of cultured chick myoblasts.
Muscle & nerve 1978;1(3):219-29.
1977: Murphy R A; Singer R H; Saide J D; Pantazis N J; Blanchard M H; Byron K S; Arnason B G; Young M
Synthesis and secretion of a high molecular weight form of nerve growth factor by skeletal muscle cells in culture.
Proceedings of the National Academy of Sciences of the United States of America 1977;74(10):4496-500.
1975: Spradling A; Singer R H; Lengyel J; Penman S
Methods with insect cells in suspension culture. I. Aedes albopictus.
Methods in cell biology 1975;10():185-94.
1973: Singer R H; Penman S
Messenger RNA in HeLa cells: kinetics of formation and decay.
Journal of molecular biology 1973;78(2):321-34.
1972: Singer R H; Penman S
Stability of HeLa cell mRNA in actinomycin.
Nature 1972;240(5376):100-2.
1972: Singer R H
Analysis of limb morphogenesis in a model system.
Developmental biology 1972;28(1):113-22.

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