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Oliver Bock

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Kais Hussein; Hans Kreipe; Guntram Büsche; Gudrun Göhring; M Görner; H-P Horny; Oliver Bock
Systemic mastocytosis (SM) with associated BCR-ABL-positive myelogenous leukaemia (SM-AHNMD): evidence that mast cells do not belong to the leukaemic clone.
Kais Hussein; Guntram Büsche; Michaela Muth; Gudrun Göhring; Hans Kreipe; Oliver Bock
Expression of myelopoiesis-associated microRNA in bone marrow cells of atypical chronic myeloid leukaemia and chronic myelomonocytic leukaemia.
Michaela Muth; Kais Hussein; Christoph Jacobi; Hans Kreipe; Oliver Bock
Hypoxia-induced down-regulation of microRNA-449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression.

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All Publications

2011: Kais Hussein; Hans Kreipe; Guntram Büsche; Gudrun Göhring; M Görner; H-P Horny; Oliver Bock
Systemic mastocytosis (SM) with associated BCR-ABL-positive myelogenous leukaemia (SM-AHNMD): evidence that mast cells do not belong to the leukaemic clone.
Leukemia 2011;25(6):1050-3.
2011: Kais Hussein; Guntram Büsche; Michaela Muth; Gudrun Göhring; Hans Kreipe; Oliver Bock
Expression of myelopoiesis-associated microRNA in bone marrow cells of atypical chronic myeloid leukaemia and chronic myelomonocytic leukaemia.
Annals of hematology 2011;90(3):307-13.
2011: Michaela Muth; Kais Hussein; Christoph Jacobi; Hans Kreipe; Oliver Bock
Hypoxia-induced down-regulation of microRNA-449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression.
Journal of translational medicine 2011;9():24.
2011: Michaela Muth; Bianca M Engelhardt; Nicolaus Kröger; Kais Hussein; Jerome Schlué; Guntram Büsche; Hans H Kreipe; Oliver Bock
Thrombospondin-1 (TSP-1) in primary myelofibrosis (PMF) - a megakaryocyte-derived biomarker which largely discriminates PMF from essential thrombocythemia.
Annals of hematology 2011;90(1):33-40.
2010: Kais Hussein; Bianca M Engelhardt; Hans Kreipe; Oliver Bock
IDH mutation analysis is not suitable for the routine molecular diagnostic algorithm in myeloproliferative and myelodysplastic neoplasms.
Blood 2010;116(23):5073-4.
2010: Michaela Muth; Guntram Büsche; Oliver Bock; Kais Hussein; Hans Kreipe
Aberrant proplatelet formation in chronic myeloproliferative neoplasms.
Leukemia research 2010;34(11):1424-9.
2010: Danny Jonigk; Katharina Theophile; Kais Hussein; Oliver Bock; Ulrich Lehmann; Clemens L Bockmeyer; Jens Gottlieb; Stefan Fischer; Andre Simon; Tobias Welte; Lavinia Maegel; Hans Kreipe; Florian Laenger
Obliterative airway remodelling in transplanted and non-transplanted lungs.
Virchows Archiv : an international journal of pathology 2010;457(3):369-80.
2010: Kais Hussein; Katharina Theophile; Guntram Büsche; Brigitte Schlegelberger; Gudrun Göhring; Hans Kreipe; Oliver Bock
Aberrant microRNA expression pattern in myelodysplastic bone marrow cells.
Leukemia research 2010;34(9):1169-74.
2010: Kais Hussein; Katharina Theophile; Guntram Büsche; Brigitte Schlegelberger; Gudrun Göhring; Hans Kreipe; Oliver Bock
Significant inverse correlation of microRNA-150/MYB and microRNA-222/p27 in myelodysplastic syndrome.
Leukemia research 2010;34(3):328-34.
2010: Michaela Muth; Katharina Theophile; Kais Hussein; Christoph Jacobi; Hans Kreipe; Oliver Bock
"Hypoxia-induced down-regulation of microRNA-449a/b impairs control over targeted SERPINE1 (PAI-1) mRNA - a mechanism involved in SERPINE1 (PAI-1) overexpression".
Journal of translational medicine 2010;8():33.
2009: Kais Hussein; Nils von neuhoff; Guntram Büsche; Thomas Buhr; Hans Kreipe; Oliver Bock
Opposite expression pattern of Src kinase Lyn in acute and chronic haematological malignancies.
Annals of hematology 2009;88(11):1059-67.
2009: Kais Hussein; Oliver Bock; Katharina Theophile; Nils von neuhoff; Thomas Buhr; Jerome Schlué; Guntram Büsche; Hans Kreipe
JAK2(V617F) allele burden discriminates essential thrombocythemia from a subset of prefibrotic-stage primary myelofibrosis.
Experimental hematology 2009;37(10):1186-1193.e7.
2009: Kais Hussein; Katharina Theophile; Katrin Denzer; Hans Kreipe; Oliver Bock
Expression of adhesion factor CD239 in bone marrow cells in chronic myeloproliferative diseases.
Journal of thrombosis and thrombolysis 2009;28(3):299-303.
2009: Oliver Bock; Michaela Muth; Katharina Theophile; Melissa Winter; Kais Hussein; Guntram Büsche; Nicolaus Kröger; Hans Kreipe
Identification of new target molecules PTK2, TGFBR2 and CD9 overexpressed during advanced bone marrow remodelling in primary myelofibrosis.
British journal of haematology 2009;146(5):510-20.
2009: Kais Hussein; Katharina Theophile; Thomas Buhr; Alexandra Beller; Hans Kreipe; Oliver Bock
Different lineage involvement in myelodysplastic/myeloproliferative disease with combined MPLW515L and JAK2V617F mutation.
British journal of haematology 2009;145(5):673-5.
2009: Kais Hussein; Oliver Bock; K Theophile; K Schulz-Bischof; A Porwit; Jerome Schlue; Danny Jonigk; Hans Kreipe
MPLW515L mutation in acute megakaryoblastic leukaemia.
Leukemia 2009;23(5):852-5.
2009: Kais Hussein; Wiebke Dralle; Katharina Theophile; Hans Kreipe; Oliver Bock
Megakaryocytic expression of miRNA 10a, 17-5p, 20a and 126 in Philadelphia chromosome-negative myeloproliferative neoplasm.
Annals of hematology 2009;88(4):325-32.
2008: Katharina Theophile; Kais Hussein; Hans Kreipe; Oliver Bock
Expression profiling of apoptosis-related genes in megakaryocytes: BNIP3 is downregulated in primary myelofibrosis.
Experimental hematology 2008;36(12):1728-38.
2008: Michael Mengel; Oliver Bock; M Priess; Hermann Haller; Hans Kreipe; Wilfried Gwinner
Expression of pro- and antifibrotic genes in protocol biopsies from renal allografts with interstitial fibrosis and tubular atrophy.
Clinical nephrology 2008;69(6):408-16.
2008: Katharina Theophile; Danny Jonigk; Hans Kreipe; Oliver Bock
Amplification of mRNA from laser-microdissected single or clustered cells in formalin-fixed and paraffin-embedded tissues for application in quantitative real-time PCR.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2008;17(2):101-6.
2008: Oliver Bock; Julia Höftmann; Katharina Theophile; Kais Hussein; Birgitt Wiese; Jerome Schlué; Hans Kreipe
Bone morphogenetic proteins are overexpressed in the bone marrow of primary myelofibrosis and are apparently induced by fibrogenic cytokines.
The American journal of pathology 2008;172(4):951-60.
2008: Katharina Theophile; Guntram Buesche; Hans Kreipe; Oliver Bock
The expression levels of telomerase catalytic subunit hTERT and oncogenic MYC in essential thrombocythemia are affected by the molecular subtype.
Annals of hematology 2008;87(4):263-8.
2008: Guntram Buesche; H Teoman; W Wilczak; Arnold Ganser; H Hecker; Ludwig Wilkens; Gudrun Göhring; Brigitte Schlegelberger; Oliver Bock; Axel Georgii; Hans Kreipe
Marrow fibrosis predicts early fatal marrow failure in patients with myelodysplastic syndromes.
Leukemia 2008;22(2):313-22.
2007: Guntram Buesche; Arnold Ganser; Brigitte Schlegelberger; Nils von neuhoff; Dorothea Gadzicki; H Hecker; Oliver Bock; B Frye; Hans Kreipe
Marrow fibrosis and its relevance during imatinib treatment of chronic myeloid leukemia.
Leukemia 2007;21(12):2420-7.
2007: Kais Hussein; Oliver Bock; Matthias Ballmaier; Gudrun Göhring; Doris Steinemann; Ulrich Lehmann; J Kemper; Thomas Buhr; Hans Kreipe
Familial polycythemia vera with non-germline JAK2(V617F) mutation sparing the abnormal and clonal granulopoiesis.
Leukemia 2007;21(12):2566-8.
2007: Guntram Büsche; Kais Hussein; Oliver Bock; Hans Kreipe
Insights into JAK2-V617F mutation in CML.
The lancet oncology 2007;8(10):863-4.
2007: Oliver Bock; Kais Hussein; Hans Kreipe
Stem cell defects in Philadelphia chromosome negative chronic myeloproliferative disorders: a phenotypic and molecular puzzle?
Current stem cell research & therapy 2007;2(3):253-63.
2007: Oliver Bock; Kais Hussein; Kai Brakensiek; Thomas Buhr; Jerome Schlué; Birgitt Wiese; Hans Kreipe
The suppressor of cytokine signalling-1 (SOCS-1) gene is overexpressed in Philadelphia chromosome negative chronic myeloproliferative disorders.
Leukemia research 2007;31(6):799-803.
2007: Kais Hussein; Oliver Bock; Anna Seegers; Michael Flasshove; Felicitas Henneke; Guntram Buesche; Hans H Kreipe
Myelofibrosis evolving during imatinib treatment of a chronic myeloproliferative disease with coexisting BCR-ABL translocation and JAK2V617F mutation.
Blood 2007;109(9):4106-7.
2007: Kais Hussein; Kai Brakensiek; Guntram Buesche; Thomas Buhr; Birgitt Wiese; Hans Kreipe; Oliver Bock
Different involvement of the megakaryocytic lineage by the JAK2 V617F mutation in Polycythemia vera, essential thrombocythemia and chronic idiopathic myelofibrosis.
Annals of hematology 2007;86(4):245-53.
2007: Oliver Bock
[Molecular diagnosis of chronic myeloproliferative diseases and myelodysplastic syndromes].
Verhandlungen der Deutschen Gesellschaft für Pathologie 2007;91():140-53.
2007: Kais Hussein; Oliver Bock; Hans Kreipe
Histological and molecular classification of chronic myeloproliferative disorders in the age of JAK2: persistence of old questions despite new answers.
Pathobiology : journal of immunopathology, molecular and cellular biology 2007;74(2):72-80.
2006: Kais Hussein; Kai Brakensiek; Matthias Ballmaier; Matthias Bormann; Gudrun Göhring; Thomas Buhr; Oliver Bock; Hans Kreipe
B-CLL developing in a patient with PV is not affected by V617F mutation of the Janus kinase 2.
European journal of haematology 2006;77(6):539-41.
2006: Oliver Bock; Kais Hussein; Michael Neusch; Jerome Schlué; Birgitt Wiese; Hans Kreipe
Transcription factor Fli-1 expression by bone marrow cells in chronic myeloproliferative disorders is independent of an underlying JAK2 (V617F) mutation.
European journal of haematology 2006;77(6):463-70.
2006: Ulrika Schade; Oliver Bock; Sylke Vornhusen; Anna Jäger; Guntram Büsche; Ulrich Lehmann; Hans Kreipe
Bone marrow infiltration pattern in B-cell chronic lymphocytic leukemia is related to immunoglobulin heavy-chain variable region mutation status and expression of 70-kd zeta-associated protein (ZAP-70).
Human pathology 2006;37(9):1153-61.
2006: Oliver Bock; Johanne Neuse; Kais Hussein; Kai Brakensiek; Guntram Buesche; Thomas Buhr; Birgitt Wiese; Hans Kreipe
Aberrant collagenase expression in chronic idiopathic myelofibrosis is related to the stage of disease but not to the JAK2 mutation status.
The American journal of pathology 2006;169(2):471-81.
2006: Oliver Bock; Guntram Büsche; Christina Koop; Sabine Schröter; Thomas Buhr; Hans Kreipe
Detection of the single hotspot mutation in the JH2 pseudokinase domain of Janus kinase 2 in bone marrow trephine biopsies derived from chronic myeloproliferative disorders.
The Journal of molecular diagnostics : JMD 2006;8(2):170-7.
2005: Fatma Akdere; Oliver Bock; Ulrich Lehmann; Ebru Serinsöz; Axel Haverich; Hans Kreipe; Michael Mengel
Quantitative mRNA expression analysis of co-stimulatory molecules in sequential biopsies from heart allografts.
Transplant international : official journal of the European Society for Organ Transplantation 2005;18(10):1197-202.
2005: Oliver Bock; Gero Loch; Ulrika Schade; Guntram Büsche; Reinhard Wasielewski; Birgitt Wiese; Hans Kreipe
Osteosclerosis in advanced chronic idiopathic myelofibrosis is associated with endothelial overexpression of osteoprotegerin.
British journal of haematology 2005;130(1):76-82.
2005: Ebru Serinsöz; Oliver Bock; Wilfried Gwinner; Anke Schwarz; Hermann Haller; Hans Kreipe; Michael Mengel
Local complement C3 expression is upregulated in humoral and cellular rejection of renal allografts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(6):1490-4.
2005: Oliver Bock; Gero Loch; Ulrika Schade; Reinhard von Wasielewski; Jerome Schlué; Hans Kreipe
Aberrant expression of transforming growth factor beta-1 (TGF beta-1) per se does not discriminate fibrotic from non-fibrotic chronic myeloproliferative disorders.
The Journal of pathology 2005;205(5):548-57.
2005: Ebru Serinsöz; Oliver Bock; Torsten Kirsch; Hermann Haller; Ulrich Lehmann; Hans Kreipe; Michael Mengel
Compartment-specific quantitative gene expression analysis after laser microdissection from archival renal allograft biopsies.
Clinical nephrology 2005;63(3):193-201.
2005: Mathewos Tessema; Florian Länger; Oliver Bock; Axel Seltsam; Kathleen Metzig; Britta Hasemeier; Hans Kreipe; Ulrich Lehmann
Down-regulation of the IGF-2/H19 locus during normal and malignant hematopoiesis is independent of the imprinting pattern.
International journal of oncology 2005;26(2):499-507.
2005: Oliver Bock; Gero Loch; Guntram Büsche; Reinhard von Wasielewski; Jerome Schlué; Hans Kreipe
Aberrant expression of platelet-derived growth factor (PDGF) and PDGF receptor-alpha is associated with advanced bone marrow fibrosis in idiopathic myelofibrosis.
Haematologica 2005;90(1):133-4.
2004: Oliver Bock; Mathewos Tessema; Ebru Serinsöz; Reinhard von Wasielewski; Guntram Büsche; Hans Kreipe
Aberrant expression of insulin-like growth factor-2 (IGF-2) in Philadelphia chromosome negative chronic myeloproliferative disorders.
Leukemia research 2004;28(11):1145-51.
2004: Ebru Serinsöz; Michael Neusch; Guntram Büsche; Reinhard Wasielewski; Hans Kreipe; Oliver Bock
Aberrant expression of beta-catenin discriminates acute myeloid leukaemia from acute lymphoblastic leukaemia.
British journal of haematology 2004;126(3):313-9.
2004: Oliver Bock; Jerome Schlué; Michael Mengel; Guntram Büsche; Ebru Serinsöz; Hans Kreipe
Thrombopoietin receptor (Mpl) expression by megakaryocytes in myeloproliferative disorders.
The Journal of pathology 2004;203(1):609-15.
2004: Oliver Bock; Ebru Serinsöz; Jerome Schlué; Hans Kreipe
Different expression levels of the telomerase catalytic subunit hTERT in myeloproliferative and myelodysplastic diseases.
Leukemia research 2004;28(5):457-60.
2004: Oliver Bock; Michael Neusch; Guntram Büsche; Michael Mengel; Hans Kreipe
Constitutive expression of the FK506 binding protein 51 (FKBP51) in bone marrow cells and megakaryocytes derived from idiopathic myelofibrosis and non-neoplastic haematopoiesis.
European journal of haematology 2004;72(4):239-44.
2003: Oliver Bock; Ebru Serinsöz; Michael Neusch; Jerome Schlué; Hans Kreipe
The polycythaemia rubra vera-1 gene is constitutively expressed by bone marrow cells and does not discriminate polycythaemia vera from reactive and other chronic myeloproliferative disorders.
British journal of haematology 2003;123(3):472-4.
2003: Oliver Bock; Dunja Reising; Hans Kreipe
Multiplex RT-PCR for the detection of common BCR-ABL fusion transcripts in paraffin-embedded tissues from patients with chronic myeloid leukemia and acute lymphoblastic leukemia.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2003;12(3):119-23.
2003: Oliver Bock; Jerome Schlué; Hans Kreipe
Reduced expression of H19 in bone marrow cells from chronic myeloproliferative disorders.
Leukemia 2003;17(4):815-6.
2003: Oliver Bock; Ulrich Lehmann; Hans Kreipe
Quantitative intra-individual monitoring of BCR-ABL transcript levels in archival bone marrow trephines of patients with chronic myeloid leukemia.
The Journal of molecular diagnostics : JMD 2003;5(1):54-60.
2002: Oliver Bock; Jerome Schlué; Ulrich Lehmann; Reinhard von Wasielewski; Florian Länger; Hans Kreipe
Megakaryocytes from chronic myeloproliferative disorders show enhanced nuclear bFGF expression.
Blood 2002;100(6):2274-5.
2001: Ulrich Lehmann; Oliver Bock; Florian Länger; Hans Kreipe
Demonstration of light chain restricted clonal B-lymphoid infiltrates in archival bone marrow trephines by quantitative real-time polymerase chain reaction.
The American journal of pathology 2001;159(6):2023-9.
2001: Oliver Bock; Hans Kreipe; U Lehmann
One-step extraction of RNA from archival biopsies.
Analytical biochemistry 2001;295(1):116-7.
2000: Ulrich Lehmann; Oliver Bock; Sabine Glöckner; Hans Kreipe
Quantitative molecular analysis of laser-microdissected paraffin-embedded human tissues.
Pathobiology : journal of immunopathology, molecular and cellular biology 2000;68(4-5):202-8.