FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Patrick Singleton

Research Profile

Anatomy

Chemicals & Drugs

Living Beings

Physiology

Disorders

Co-author Network

Publications

TOP 3
Yulia Ephstein; Joe G. N. Garcia; Weiguo Chen; Steven M Dudek; Prasad Vk Kanteti; Ravi Salgia; Patrick A Singleton; Lichun Wang; Jeffrey Jacobson
Critical role of S1PR1 and integrin β4 in HGF/c-Met-mediated increases in vascular integrity.
Xiaoguang Sun; Leonor Thomson; Michael S Wade; Jing Zhao; Tong Zhou; Patrick Belvitch; Eddie T Chiang; Steven M Dudek; Harry Ischiropoulos; Jeffrey Jacobson; Eleftheria Letsiou; Bin Liu; Roberto Machado; Liliana Moreno Vinasco; Viswanathan Natarajan; Ioannis Parastatidis; Saad Sammani; Patrick A Singleton; Joe G. N. Garcia
Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury.
Frances E Lennon; Jonathan Moss; Patrick A Singleton
The μ-opioid receptor in cancer progression: is there a direct effect?

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Patrick Singleton (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Yulia Ephstein; Joe G. N. Garcia; Weiguo Chen; Steven M Dudek; Prasad Vk Kanteti; Ravi Salgia; Patrick A Singleton; Lichun Wang; Jeffrey Jacobson
Critical role of S1PR1 and integrin β4 in HGF/c-Met-mediated increases in vascular integrity.
The Journal of biological chemistry 2013;288(4):2191-200.
2012: Xiaoguang Sun; Leonor Thomson; Michael S Wade; Jing Zhao; Tong Zhou; Patrick Belvitch; Eddie T Chiang; Steven M Dudek; Harry Ischiropoulos; Jeffrey Jacobson; Eleftheria Letsiou; Bin Liu; Roberto Machado; Liliana Moreno Vinasco; Viswanathan Natarajan; Ioannis Parastatidis; Saad Sammani; Patrick A Singleton; Joe G. N. Garcia
Sphingosine-1-phosphate receptor-3 is a novel biomarker in acute lung injury.
American journal of respiratory cell and molecular biology 2012;47(5):628-36.
2012: Frances E Lennon; Jonathan Moss; Patrick A Singleton
The μ-opioid receptor in cancer progression: is there a direct effect?
Anesthesiology 2012;116(4):940-5.
2012: Frances E Lennon; Bolot Mambetsariev; Tamara Mirzapoiazova; Jonathan Moss; Ravi Salgia; Patrick A Singleton
Overexpression of the μ-opioid receptor in human non-small cell lung cancer promotes Akt and mTOR activation, tumor growth, and metastasis.
Anesthesiology 2012;116(4):857-67.
2012: Peter Usatyuk; Srikanth Pendyala; Patrick A Singleton; Sara M Camp; Steven M Dudek; Joe G. N. Garcia; Irina A Gorshkova; Donghong He; Satish K Kalari; Jaideep Moitra; Viswanathan Natarajan
Novel role for non-muscle myosin light chain kinase (MLCK) in hyperoxia-induced recruitment of cytoskeletal proteins, NADPH oxidase activation, and reactive oxygen species generation in lung endothelium.
The Journal of biological chemistry 2012;287(12):9360-75.
2011: Biji Mathew; Frances E Lennon; Jessica Siegler; Tamara Mirzapoiazova; Nurbek Mambetsariev; Saad Sammani; Lynnette M Gerhold; Patrick J LaRiviere; Chin-Tu Chen; Joe G. N. Garcia; Ravi Salgia; Jonathan Moss; Patrick A Singleton
The novel role of the mu opioid receptor in lung cancer progression: a laboratory investigation.
Anesthesia and analgesia 2011;112(3):558-67.
2011: Tamara Mirzapoiazova; Jaideep Moitra; Liliana Moreno Vinasco; Saad Sammani; Jerry R Turner; Eddie T Chiang; Carrie Evenoski; T Wang; Patrick A Singleton; Yong Huang; Yves lussier; D Martin Watterson; Steven M Dudek; Joe G. N. Garcia
Non-muscle myosin light chain kinase isoform is a viable molecular target in acute inflammatory lung injury.
American journal of respiratory cell and molecular biology 2011;44(1):40-52.
2010: Steven M Dudek; Eddie T Chiang; Sara M Camp; Yurong Guo; Jing Zhao; Mary E Brown; Patrick A Singleton; Lichun Wang; Anjali Desai; Fernando T Arce; Ratnesh Lal; Jennifer E Van Eyk; Syed Z Imam; Joe G. N. Garcia
Abl tyrosine kinase phosphorylates nonmuscle Myosin light chain kinase to regulate endothelial barrier function.
Molecular biology of the cell 2010;21(22):4042-56.
2010: Patrick A Singleton; Tamara Mirzapoiazova; Yurong Guo; Saad Sammani; Nurbek Mambetsariev; Frances E Lennon; Liliana Moreno Vinasco; Joe G. N. Garcia
High-molecular-weight hyaluronan is a novel inhibitor of pulmonary vascular leakiness.
American journal of physiology. Lung cellular and molecular physiology 2010;299(5):L639-51.
2010: Saad Sammani; Liliana Moreno Vinasco; Tamara Mirzapoiazova; Patrick A Singleton; Eddie T Chiang; Carrie L Evenoski; T Wang; Biji Mathew; Aliya Husain; Jaideep Moitra; Xiaoguang Sun; Luis Nunez; Jeffrey Jacobson; Steven M Dudek; Viswanathan Natarajan; Joe G. N. Garcia
Differential effects of sphingosine 1-phosphate receptors on airway and vascular barrier function in the murine lung.
American journal of respiratory cell and molecular biology 2010;43(4):394-402.
2010: Patrick A Singleton; Jonathan Moss
Effect of perioperative opioids on cancer recurrence: a hypothesis.
Future oncology (London, England) 2010;6(8):1237-42.
2010: Leonardo Faoro; Patrick A Singleton; Gustavo M Cervantes; Frances E Lennon; Nicholas W Choong; Rajani Kanteti; Ben Ferguson; Aliya N Husain; Maria S Tretiakova; Nithya Ramnath; Everett E Vokes; Ravi Salgia
EphA2 mutation in lung squamous cell carcinoma promotes increased cell survival, cell invasion, focal adhesions, and mammalian target of rapamycin activation.
The Journal of biological chemistry 2010;285(24):18575-85.
2010: Nurbek Mambetsariev; Tamara Mirzapoiazova; Bolot Mambetsariev; Saad Sammani; Frances E Lennon; Joe G. N. Garcia; Patrick A Singleton
Hyaluronic Acid binding protein 2 is a novel regulator of vascular integrity.
Arteriosclerosis, thrombosis, and vascular biology 2010;30(3):483-90.
2010: Patrick A Singleton; Nurbek Mambetsariev; Frances E Lennon; Biji Mathew; Jessica H Siegler; Liliana Moreno Vinasco; Ravi Salgia; Jonathan Moss; Joe G. N. Garcia
Methylnaltrexone potentiates the anti-angiogenic effects of mTOR inhibitors.
Journal of angiogenesis research 2010;2(1):5.
2009: Patrick A Singleton; Srikanth Pendyala; Irina A Gorshkova; Nurbek Mambetsariev; Jaideep Moitra; Joe G. N. Garcia; Viswanathan Natarajan
Dynamin 2 and c-Abl are novel regulators of hyperoxia-mediated NADPH oxidase activation and reactive oxygen species production in caveolin-enriched microdomains of the endothelium.
The Journal of biological chemistry 2009;284(50):34964-75.
2009: Jing Zhao; Patrick A Singleton; Mary E Brown; Steven M Dudek; Joe G. N. Garcia
Phosphotyrosine protein dynamics in cell membrane rafts of sphingosine-1-phosphate-stimulated human endothelium: role in barrier enhancement.
Cellular signalling 2009;21(12):1945-60.
2009: Soundararajan Krishnaswamy; Rajani Kanteti; Jonathan S Duke-Cohan; Sivakumar Loganathan; Wanqing Liu; Patrick C Ma; Martin Sattler; Patrick A Singleton; Nithya Ramnath; Federico Innocenti; Dan L Nicolae; Zheng Ouyang; Jie Liang; John Minna; Mark F. Kozloff; Mark K Ferguson; Viswanathan Natarajan; Yi-Ching Wang; Joe G. N. Garcia; Everett E Vokes; Ravi Salgia
Ethnic differences and functional analysis of MET mutations in lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(18):5714-23.
2009: Nuala J Meyer; Yong Huang; Patrick A Singleton; Saad Sammani; Jaideep Moitra; Carrie L Evenoski; Aliya N Husain; Sumegha Mitra; Liliana Moreno Vinasco; Jeffrey Jacobson; Yves lussier; Joe G. N. Garcia
GADD45a is a novel candidate gene in inflammatory lung injury via influences on Akt signaling.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2009;23(5):1325-37.
2009: Patrick A Singleton; Santipongse Chatchavalvanich; Panfeng Fu; Junjie Xing; Anna A Birukova; Jennifer A Fortune; Alexander M Klibanov; Joe G. N. Garcia; Konstantin G Birukov
Akt-mediated transactivation of the S1P1 receptor in caveolin-enriched microdomains regulates endothelial barrier enhancement by oxidized phospholipids.
Circulation research 2009;104(8):978-86.
2008: Patrick A Singleton; Joe G. N. Garcia; Jonathan Moss
Synergistic effects of methylnaltrexone with 5-fluorouracil and bevacizumab on inhibition of vascular endothelial growth factor-induced angiogenesis.
Molecular cancer therapeutics 2008;7(6):1669-79.
2008: Liliana Moreno Vinasco; Mardi Gomberg-Maitland; Michael L Maitland; Apurva A Desai; Patrick A Singleton; Saad Sammani; Lee Sam; Yang Liu; Aliya N Husain; Roberto M Lang; Mark J Ratain; Yves lussier; Joe G. N. Garcia
Genomic assessment of a multikinase inhibitor, sorafenib, in a rodent model of pulmonary hypertension.
Physiological genomics 2008;33(2):278-91.
2007: Patrick A Singleton; Ravi Salgia; Liliana Moreno Vinasco; Jaideep Moitra; Saad Sammani; Tamara Mirzapoiazova; Joe G. N. Garcia
CD44 regulates hepatocyte growth factor-mediated vascular integrity. Role of c-Met, Tiam1/Rac1, dynamin 2, and cortactin.
The Journal of biological chemistry 2007;282(42):30643-57.
2007: Steven M Dudek; S M Camp; Eddie T Chiang; Patrick A Singleton; Peter Usatyuk; Yutong Zhao; Viswanathan Natarajan; Joe G. N. Garcia
Pulmonary endothelial cell barrier enhancement by FTY720 does not require the S1P1 receptor.
Cellular signalling 2007;19(8):1754-64.
2007: Patrick A Singleton; Liliana Moreno Vinasco; Saad Sammani; Sherry L Wanderling; Jonathan Moss; Joe G. N. Garcia
Attenuation of vascular permeability by methylnaltrexone: role of mOP-R and S1P3 transactivation.
American journal of respiratory cell and molecular biology 2007;37(2):222-31.
2007: Yurong Guo; Patrick A Singleton; Austin Rowshan; Marjan Gucek; Robert N Cole; David Raymond Graham; Jennifer E Van Eyk; Joe G. N. Garcia
Quantitative proteomics analysis of human endothelial cell membrane rafts: evidence of MARCKS and MRP regulation in the sphingosine 1-phosphate-induced barrier enhancement.
Molecular & cellular proteomics : MCP 2007;6(4):689-96.
2006: Patrick A Singleton; Steven M Dudek; Shwu-Fan Ma; Joe G. N. Garcia
Transactivation of sphingosine 1-phosphate receptors is essential for vascular barrier regulation. Novel role for hyaluronan and CD44 receptor family.
The Journal of biological chemistry 2006;281(45):34381-93.
2006: Jeffrey Jacobson; Steven M Dudek; Patrick A Singleton; Irina Kolosova; Alexander Dmitriyevich Verin; Joe G. N. Garcia
Endothelial cell barrier enhancement by ATP is mediated by the small GTPase Rac and cortactin.
American journal of physiology. Lung cellular and molecular physiology 2006;291(2):L289-95.
2006: Patrick A Singleton; Mark W Lingen; Mary Jo Fekete; Joe G. N. Garcia; Jonathan Moss
Methylnaltrexone inhibits opiate and VEGF-induced angiogenesis: role of receptor transactivation.
Microvascular research 2006;72(1-2):3-11.
2005: Patrick A Singleton; Steven M Dudek; Eddie T Chiang; Joe G. N. Garcia
Regulation of sphingosine 1-phosphate-induced endothelial cytoskeletal rearrangement and barrier enhancement by S1P1 receptor, PI3 kinase, Tiam1/Rac1, and alpha-actinin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(12):1646-56.
2005: James H Finigan; Steven M Dudek; Patrick A Singleton; Eddie T Chiang; Jeffrey Jacobson; Sara M Camp; Shui Q Ye; Joe G. N. Garcia
Activated protein C mediates novel lung endothelial barrier enhancement: role of sphingosine 1-phosphate receptor transactivation.
The Journal of biological chemistry 2005;280(17):17286-93.